sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4nqn | Y1Z | Bromodomain-containing protein 9 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4nqn | Y1Z | Bromodomain-containing protein 9 | / | 1.000 | |
| 4uyg | 73B | Bromodomain-containing protein 2 | / | 0.572 | |
| 5fe1 | 12Q | Histone acetyltransferase KAT2B | 2.3.1.48 | 0.554 | |
| 4bjx | 73B | Bromodomain-containing protein 4 | / | 0.518 | |
| 2bdy | UNB | Prothrombin | 3.4.21.5 | 0.516 | |
| 4mr6 | 1K0 | Bromodomain-containing protein 2 | / | 0.513 | |
| 4j1p | 1K0 | Bromodomain-containing protein 2 | / | 0.511 | |
| 4o74 | R78 | Bromodomain-containing protein 4 | / | 0.511 | |
| 4flp | JQ1 | Bromodomain testis-specific protein | / | 0.509 | |
| 4ogi | R78 | Bromodomain-containing protein 4 | / | 0.509 | |
| 4mr5 | 1K0 | Bromodomain-containing protein 2 | / | 0.508 | |
| 4a9o | A9O | Bromodomain-containing protein 2 | / | 0.507 | |
| 4akn | S5B | Bromodomain-containing protein 2 | / | 0.507 | |
| 2yem | WSH | Bromodomain-containing protein 4 | / | 0.505 | |
| 3nn6 | HNK | 6-hydroxy-L-nicotine oxidase | / | 0.504 | |
| 3d0b | SNX | Heat shock protein HSP 90-alpha | / | 0.501 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.501 | |
| 2yel | WSH | Bromodomain-containing protein 4 | / | 0.500 | |
| 4j3i | 1K0 | Bromodomain-containing protein 4 | / | 0.500 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.499 | |
| 4ir5 | IR5 | Bromodomain adjacent to zinc finger domain protein 2B | / | 0.499 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.498 | |
| 4jq4 | IMN | Aldo-keto reductase family 1 member C2 | / | 0.498 | |
| 4nr5 | 2LL | CREB-binding protein | / | 0.498 | |
| 5bt5 | 2LO | Bromodomain-containing protein 2 | / | 0.498 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.497 | |
| 4a9l | P9L | Bromodomain-containing protein 4 | / | 0.496 | |
| 4i6f | 1C7 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.496 | |
| 2h55 | DZ8 | Heat shock protein HSP 90-alpha | / | 0.495 | |
| 4mr4 | 1K0 | Bromodomain-containing protein 4 | / | 0.495 | |
| 4hxr | 1A4 | Bromodomain-containing protein 4 | / | 0.494 | |
| 3zyu | 1GH | Bromodomain-containing protein 4 | / | 0.493 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.492 | |
| 3ad9 | NAD | Subunit alpha of sarocosine oxidase | / | 0.491 | |
| 4c67 | L5S | Bromodomain-containing protein 4 | / | 0.490 | |
| 4kxj | P34 | Nucleoprotein | / | 0.490 | |
| 4bw2 | UTH | Bromodomain-containing protein 4 | / | 0.489 | |
| 4j0r | 1H2 | Bromodomain-containing protein 4 | / | 0.489 | |
| 2fwy | H64 | Heat shock protein HSP 90-alpha | / | 0.488 | |
| 4aoi | 4K0 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.488 | |
| 4mep | 24Y | Bromodomain-containing protein 4 | / | 0.488 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.487 | |
| 1zgv | 501 | Prothrombin | 3.4.21.5 | 0.487 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.487 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.487 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.486 | |
| 4hy6 | FJ1 | Heat shock protein HSP 90-alpha | / | 0.486 | |
| 3o0i | P54 | Heat shock protein HSP 90-alpha | / | 0.485 | |
| 4lyw | 21Q | Bromodomain-containing protein 4 | / | 0.484 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.483 | |
| 2xvw | 9NR | Serum albumin | / | 0.483 | |
| 3o6o | 94M | Heat shock protein 83 | / | 0.483 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.483 | |
| 4nra | 2LW | Bromodomain adjacent to zinc finger domain protein 2B | / | 0.483 | |
| 5kbw | RBF | Riboflavin transporter RibU | / | 0.482 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.481 | |
| 1uyi | PUZ | Heat shock protein HSP 90-alpha | / | 0.481 | |
| 2fsz | OHT | Estrogen receptor beta | / | 0.481 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.481 | |
| 3bi6 | 396 | Wee1-like protein kinase | 2.7.10.2 | 0.481 | |
| 4qzu | RTL | Retinol-binding protein 2 | / | 0.481 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.480 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.480 | |
| 4ap7 | F47 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.480 | |
| 4dh6 | 0KN | Beta-secretase 1 | 3.4.23.46 | 0.480 | |
| 2wi7 | 2KL | Heat shock protein HSP 90-alpha | / | 0.479 | |
| 3aqa | BYH | Bromodomain-containing protein 2 | / | 0.479 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.478 | |
| 2xvv | 9DN | Serum albumin | / | 0.478 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.478 | |
| 4nqm | Y1Z | Bromodomain-containing protein 4 | / | 0.477 | |
| 1uyc | PU7 | Heat shock protein HSP 90-alpha | / | 0.476 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.476 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.476 | |
| 1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.475 | |
| 2fai | 459 | Estrogen receptor | / | 0.475 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.475 | |
| 4hxs | 1A3 | Bromodomain-containing protein 4 | / | 0.475 | |
| 4j0s | 1H3 | Bromodomain-containing protein 4 | / | 0.475 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.475 | |
| 5eq1 | BEA | Peregrin | / | 0.475 | |
| 1nyx | DRF | Peroxisome proliferator-activated receptor gamma | / | 0.474 | |
| 2e7z | MGD | Acetylene hydratase | / | 0.474 | |
| 2pks | G44 | Prothrombin | 3.4.21.5 | 0.474 | |
| 2wi4 | ZZ4 | Heat shock protein HSP 90-alpha | / | 0.474 | |
| 2zhw | 12U | Prothrombin | 3.4.21.5 | 0.474 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.474 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.474 | |
| 4bw1 | S5B | Bromodomain-containing protein 4 | / | 0.474 | |
| 4fxf | ATP | Pyruvate kinase PKM | 2.7.1.40 | 0.474 | |
| 4guy | KLJ | Macrophage metalloelastase | 3.4.24.65 | 0.474 | |
| 4men | 25K | Bromodomain-containing protein 4 | / | 0.474 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.473 | |
| 3ft8 | MOJ | Heat shock protein HSP 90-alpha | / | 0.473 | |
| 4a9n | A9N | Bromodomain-containing protein 2 | / | 0.473 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.473 | |
| 4gg5 | 0J3 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.473 | |
| 4gur | FAD | Lysine-specific histone demethylase 1B | 1 | 0.473 | |
| 4o78 | SAV | Bromodomain-containing protein 4 | / | 0.473 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.472 | |
| 1yzq | GNP | Ras-related protein Rab-6A | / | 0.471 | |
| 2wkm | PFY | Hepatocyte growth factor receptor | 2.7.10.1 | 0.471 | |
| 2yei | XQI | Heat shock protein HSP 90-alpha | / | 0.471 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.471 | |
| 3sqw | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.471 | |
| 4bdr | KAI | Glutamate receptor ionotropic, kainate 2 | / | 0.471 | |
| 5dfc | EAM | Bromodomain-containing protein 2 | / | 0.471 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.471 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.470 | |
| 1u2r | SO1 | Elongation factor 2 | / | 0.470 | |
| 2ij7 | TPF | Mycocyclosin synthase | 1.14.21.9 | 0.470 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.470 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.470 | |
| 4alh | A9P | Bromodomain-containing protein 2 | / | 0.470 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.470 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.469 | |
| 2mok | FMN | Flavodoxin 1 | / | 0.469 | |
| 2z2w | 770 | Wee1-like protein kinase | 2.7.10.2 | 0.469 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.469 | |
| 3hz1 | 42C | Heat shock protein HSP 90-alpha | / | 0.469 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.469 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.468 | |
| 2yac | 937 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.468 | |
| 3qdd | 94M | Heat shock protein HSP 90-alpha | / | 0.468 | |
| 4bw3 | 9BM | Bromodomain-containing protein 4 | / | 0.468 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.468 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 2ek4 | SAH | Diphthine synthase | / | 0.467 | |
| 2ykj | YKJ | Heat shock protein HSP 90-alpha | / | 0.467 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.467 | |
| 4lsj | LSJ | Glucocorticoid receptor | / | 0.467 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.466 | |
| 1uwh | BAX | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.466 | |
| 2ag0 | TPP | Benzaldehyde lyase | / | 0.466 | |
| 2yk2 | YJW | Heat shock protein HSP 90-alpha | / | 0.466 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.466 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.466 | |
| 3ho2 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.466 | |
| 4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.466 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.465 | |
| 1l5r | 700 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.465 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.465 | |
| 1uy9 | PU6 | Heat shock protein HSP 90-alpha | / | 0.465 | |
| 2ag1 | TPP | Benzaldehyde lyase | / | 0.465 | |
| 2hu6 | 37A | Macrophage metalloelastase | 3.4.24.65 | 0.465 | |
| 2x1z | PID | Peridinin-chlorophyll a-binding protein 1, chloroplastic | / | 0.465 | |
| 3biz | 61E | Wee1-like protein kinase | 2.7.10.2 | 0.465 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.465 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.465 | |
| 1ae8 | AZL | Prothrombin | 3.4.21.5 | 0.464 | |
| 1dfo | PLG | Serine hydroxymethyltransferase | 2.1.2.1 | 0.464 | |
| 1qv0 | CZH | Obelin | / | 0.464 | |
| 1uyh | PU0 | Heat shock protein HSP 90-alpha | / | 0.464 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 2ydw | WSH | Bromodomain-containing protein 2 | / | 0.464 | |
| 3qiy | QI1 | Botulinum neurotoxin type A | 3.4.24.69 | 0.464 | |
| 4l4f | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.464 | |
| 1aiq | CB3 | Thymidylate synthase | / | 0.463 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.463 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.463 | |
| 2fon | FAD | Acyl-coenzyme A oxidase | / | 0.463 | |
| 2hps | CTZ | Ca2+-triggered coelenterazine-binding protein 1 | / | 0.463 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.463 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 2zhq | 27U | Prothrombin | 3.4.21.5 | 0.463 | |
| 3dux | 64U | Prothrombin | 3.4.21.5 | 0.463 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.463 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.463 | |
| 3zvu | A8S | Abscisic acid receptor PYR1 | / | 0.463 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.463 | |
| 4ug2 | NGI | Adenosine receptor A2a | / | 0.463 | |
| 1knp | FAD | L-aspartate oxidase | 1.4.3.16 | 0.462 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 2qg2 | A91 | Heat shock protein HSP 90-alpha | / | 0.462 | |
| 3b9l | AZZ | Serum albumin | / | 0.462 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.462 | |
| 3dds | 26B | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.462 | |
| 3hz1 | 37D | Heat shock protein HSP 90-alpha | / | 0.462 | |
| 4c66 | H4C | Bromodomain-containing protein 4 | / | 0.462 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.462 | |
| 4r1l | ADP | Phenylacetate-coenzyme A ligase | / | 0.462 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.462 | |
| 5cmx | 0G6 | Prothrombin | 3.4.21.5 | 0.462 | |
| 1jtu | LYB | Thymidylate synthase | / | 0.461 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.461 | |
| 1xj7 | DHT | Androgen receptor | / | 0.461 | |
| 2aa5 | STR | Mineralocorticoid receptor | / | 0.461 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.461 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.461 | |
| 3zhr | TPP | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.461 | |
| 3zze | 6XP | Hepatocyte growth factor receptor | 2.7.10.1 | 0.461 | |
| 1d4d | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.460 | |
| 1flm | FMN | FMN-binding protein | / | 0.460 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.460 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 1yim | CM4 | Estrogen receptor | / | 0.460 | |
| 2op1 | 8PC | Enoyl-ACP reductase | / | 0.460 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 2zf0 | 51U | Prothrombin | 3.4.21.5 | 0.460 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.460 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.460 | |
| 3sqx | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.460 | |
| 4c71 | 7RD | 3-oxoacyl-ACP synthase | / | 0.460 | |
| 4meq | 25O | Bromodomain-containing protein 4 | / | 0.460 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.460 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 1kmy | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.459 | |
| 1pq6 | 965 | Oxysterols receptor LXR-beta | / | 0.459 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 2bxq | IMN | Serum albumin | / | 0.459 | |
| 2gfx | PMN | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.459 | |
| 2p2x | SAH | Diphthine synthase | / | 0.459 | |
| 4fa3 | 0SL | Aldo-keto reductase family 1 member C3 | / | 0.459 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.459 | |
| 4l4c | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.459 | |
| 1axw | MTX | Thymidylate synthase | / | 0.458 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 1tdu | DUR | Thymidylate synthase | / | 0.458 | |
| 1uy7 | PU4 | Heat shock protein HSP 90-alpha | / | 0.458 | |
| 1uy8 | PU5 | Heat shock protein HSP 90-alpha | / | 0.458 | |
| 1ypk | CCR | Prothrombin | 3.4.21.5 | 0.458 | |
| 1z6l | FAD | Polyamine oxidase FMS1 | / | 0.458 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.458 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.458 | |
| 2piv | DHT | Androgen receptor | / | 0.458 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.458 | |
| 3akl | ADP | Serine/threonine-protein kinase CtkA | 2.7.11.1 | 0.458 | |
| 3d74 | NBB | Pheromone-binding protein ASP1 | / | 0.458 | |
| 3h0a | 9RA | Retinoic acid receptor RXR-alpha | / | 0.458 | |
| 3mcy | ZH1 | FimH | / | 0.458 | |
| 3zxz | KRW | Hepatocyte growth factor receptor | 2.7.10.1 | 0.458 | |
| 4ask | K0I | Lysine-specific demethylase 6B | 1.14.11 | 0.458 | |
| 4xwr | FAD | Cholesterol oxidase | 1.1.3.6 | 0.458 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.457 | |
| 1qzf | CB3 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.457 | |
| 2v2z | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.457 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.457 | |
| 3dhc | CYK | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.457 | |
| 3kdt | 7HA | Peroxisome proliferator-activated receptor alpha | / | 0.457 | |
| 4g2y | NI5 | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.457 | |
| 4hby | 13F | Bromodomain-containing protein 4 | / | 0.457 | |
| 4uoh | ADP | Nucleoside diphosphate kinase | / | 0.457 | |
| 1nqv | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.456 | |
| 1sbr | VIB | Putative HMP/thiamine-binding protein YkoF | / | 0.456 | |
| 1v45 | 3DG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.456 | |
| 1yrc | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 3k7m | FAD | 6-hydroxy-L-nicotine oxidase | / | 0.456 | |
| 3qiz | QI2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.456 | |
| 4egn | TWO | Cytochrome P450 | / | 0.456 | |
| 4ktt | SAM | S-adenosylmethionine synthase isoform type-2 | 2.5.1.6 | 0.456 | |
| 4lr6 | 1XA | Bromodomain-containing protein 4 | / | 0.456 | |
| 4py6 | R78 | Bromodomain protein, putative | / | 0.456 | |
| 3p0g | P0G | Beta-2 adrenergic receptor | / | 0.456 | |
| 2acl | REA | Retinoic acid receptor RXR-alpha | / | 0.455 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
| 2i1m | 5CN | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.455 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.455 | |
| 2uz1 | TPP | Benzaldehyde lyase | / | 0.455 | |
| 3bbp | GTP | Ras-related protein Rab-6A | / | 0.455 | |
| 3ozc | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.455 | |
| 4d04 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.455 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.455 | |
| 4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.455 | |
| 1daj | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1e1l | NAP | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.454 | |
| 1p7t | ACO | Malate synthase G | / | 0.454 | |
| 1sd1 | FMC | S-methyl-5'-thioadenosine phosphorylase | / | 0.454 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 2dxx | SAH | Diphthine synthase | / | 0.454 | |
| 2e83 | FMN | FMN-binding protein | / | 0.454 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.454 | |
| 2wqo | VGK | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.454 | |
| 2zfq | 45U | Prothrombin | 3.4.21.5 | 0.454 | |
| 3eq0 | 2TS | Prothrombin | 3.4.21.5 | 0.454 | |
| 3g11 | P9C | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.454 | |
| 3gyi | FAD | Cholesterol oxidase | 1.1.3.6 | 0.454 | |
| 4cfk | LY2 | Bromodomain-containing protein 4 | / | 0.454 | |
| 4if5 | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.454 | |
| 4lrg | 1XB | Bromodomain-containing protein 4 | / | 0.454 | |
| 4rek | FAD | Cholesterol oxidase | 1.1.3.6 | 0.454 | |
| 1uyd | PU8 | Heat shock protein HSP 90-alpha | / | 0.453 | |
| 1uye | PU9 | Heat shock protein HSP 90-alpha | / | 0.453 | |
| 1uyf | PU1 | Heat shock protein HSP 90-alpha | / | 0.453 | |
| 2bl9 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.453 | |
| 2fjd | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.453 | |
| 2piw | DHT | Androgen receptor | / | 0.453 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.453 | |
| 3qg2 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.453 | |
| 3zc5 | W9Z | Hepatocyte growth factor receptor | 2.7.10.1 | 0.453 | |
| 4mv8 | ACP | Biotin carboxylase | 6.3.4.14 | 0.453 | |
| 1j3j | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.452 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 1s17 | GNR | Peptide deformylase | / | 0.452 | |
| 1xq3 | R18 | Androgen receptor | / | 0.452 | |
| 2bak | AQZ | Mitogen-activated protein kinase 14 | / | 0.452 | |
| 2dwb | ANP | Aurora kinase A | 2.7.11.1 | 0.452 | |
| 2hux | SAH | Diphthine synthase | / | 0.452 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.452 | |
| 2pb6 | SAH | Diphthine synthase | / | 0.452 | |
| 2qw8 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.452 | |
| 2rku | R78 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.452 | |
| 2w71 | L23 | Biotin carboxylase | 6.3.4.14 | 0.452 | |
| 2xkd | T3M | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.452 | |
| 2xlr | NAP | Putative flavin-containing monooxygenase | / | 0.452 | |
| 2zgb | 21U | Prothrombin | 3.4.21.5 | 0.452 | |
| 3d73 | NBB | Pheromone-binding protein ASP1 | / | 0.452 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.452 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3qto | 10P | Prothrombin | 3.4.21.5 | 0.452 | |
| 4a9y | AQZ | Mitogen-activated protein kinase 14 | / | 0.452 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.452 | |
| 4f3i | 0S6 | Bromodomain-containing protein 4 | / | 0.452 | |
| 4hrq | AZG | Cytidine and deoxycytidylate deaminase zinc-binding region | / | 0.452 | |
| 4mf1 | 29Y | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.452 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.452 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.451 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.451 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.451 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.451 | |
| 2zfp | 19U | Prothrombin | 3.4.21.5 | 0.451 | |
| 3a6q | FMN | FMN-binding protein | / | 0.451 | |
| 3c36 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.451 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.451 | |
| 3i7i | 518 | Collagenase 3 | 3.4.24 | 0.451 | |
| 3own | 3OX | Renin | 3.4.23.15 | 0.451 | |
| 3qzy | FAD | FAD-linked sulfhydryl oxidase | / | 0.451 | |
| 4bdo | KAI | Glutamate receptor ionotropic, kainate 2 | / | 0.451 | |
| 4i0f | 1BF | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 4zir | ANP | Energy-coupling factor transporter ATP-binding protein EcfA2 | 3.6.3 | 0.451 | |
| 4zir | ANP | Energy-coupling factor transporter ATP-binding protein EcfA1 | / | 0.451 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 1g28 | FMN | PHY3 | / | 0.450 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.450 | |
| 1thn | ADP | Anti-sigma F factor | / | 0.450 | |
| 1zrb | 062 | Prothrombin | 3.4.21.5 | 0.450 | |
| 2aq7 | TL5 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.450 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 2jh0 | 701 | Prothrombin | 3.4.21.5 | 0.450 | |
| 2pca | SAH | Diphthine synthase | / | 0.450 | |
| 2vb8 | TLM | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.450 | |
| 2wya | HMG | Hydroxymethylglutaryl-CoA synthase, mitochondrial | 2.3.3.10 | 0.450 | |
| 3dnd | LL2 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.450 | |
| 3eks | CY9 | Actin-5C | / | 0.450 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.450 | |
| 3lxi | CAM | Cytochrome P450 | / | 0.450 | |
| 3qwc | 98P | Prothrombin | 3.4.21.5 | 0.450 | |
| 3v0t | ATR | Perakine reductase | 1.1.1.317 | 0.450 | |
| 4a9m | P9M | Bromodomain-containing protein 2 | / | 0.450 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 4l0q | NAD | Alcohol dehydrogenase class-3 | / | 0.450 | |
| 4m11 | MXM | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.450 | |
| 4u0m | GTP | Cyclic GMP-AMP synthase | / | 0.450 | |
| 5d6l | CAU | Beta-2 adrenergic receptor | / | 0.450 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.449 | |
| 1uy6 | PU3 | Heat shock protein HSP 90-alpha | / | 0.449 | |
| 2acl | L05 | Oxysterols receptor LXR-alpha | / | 0.449 | |
| 2hm9 | TRR | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 2i1v | ADP | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 | 2.7.1.105 | 0.449 | |
| 2rl5 | 2RL | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.449 | |
| 2zda | 32U | Prothrombin | 3.4.21.5 | 0.449 | |
| 3ddw | 055 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.449 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3owj | 1EL | Casein kinase II subunit alpha | 2.7.11.1 | 0.449 | |
| 3vg9 | ZMA | Adenosine receptor A2a | / | 0.449 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.449 | |
| 4alg | 1GH | Bromodomain-containing protein 2 | / | 0.449 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 4hxo | 1A6 | Bromodomain-containing protein 4 | / | 0.449 | |
| 1e26 | GPB | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1e7a | PFL | Serum albumin | / | 0.448 | |
| 1snu | STU | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.448 | |
| 1usc | FMN | Monooxygenase | / | 0.448 | |
| 1ypj | UIB | Prothrombin | 3.4.21.5 | 0.448 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.448 | |
| 2bbq | PFG | Thymidylate synthase | / | 0.448 | |
| 2m56 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 2toh | HBI | Tyrosine 3-monooxygenase | 1.14.16.2 | 0.448 | |
| 3dhb | C6L | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.448 | |
| 3h59 | H59 | Genome polyprotein | 2.7.7.48 | 0.448 | |
| 3hxd | BD7 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.448 | |
| 3zra | ORB | Progesterone receptor | / | 0.448 | |
| 4bah | MEL | Prothrombin | 3.4.21.5 | 0.448 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.448 | |
| 4efu | EFU | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 4g8c | C6L | Alpha/beta hydrolase fold protein | / | 0.448 | |
| 4mub | OAQ | Sulfotransferase oxamniquine resistance protein | / | 0.448 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.448 | |
| 4nqg | CZH | Mitrocomin | / | 0.448 | |
| 4nyv | 15E | CREB-binding protein | / | 0.448 | |
| 4r3a | ANP | Blue-light-activated histidine kinase 2 | 2.7.13.3 | 0.448 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.448 | |
| 5hwp | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.448 | |
| 1bnt | AL2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.447 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1swt | BTN | Streptavidin | / | 0.447 | |
| 1umc | TDP | 2-oxoisovalerate dehydrogenase subunit alpha | 1.2.4.4 | 0.447 | |
| 1umc | TDP | 2-oxoisovalerate dehydrogenase subunit beta | 1.2.4.4 | 0.447 | |
| 2e4n | SAH | Diphthine synthase | / | 0.447 | |
| 2pch | SAH | Diphthine synthase | / | 0.447 | |
| 2zc9 | 22U | Prothrombin | 3.4.21.5 | 0.447 | |
| 3dog | NNN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 3e39 | FMN | Nitroreductase | / | 0.447 | |
| 3el7 | PD3 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.447 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.447 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.447 | |
| 3ipu | O40 | Oxysterols receptor LXR-alpha | / | 0.447 | |
| 3nf8 | CDQ | Gag-Pol polyprotein | / | 0.447 | |
| 4gg7 | 0J8 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.447 | |
| 4gpj | 0Q1 | Bromodomain-containing protein 4 | / | 0.447 | |
| 4h96 | 14Q | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 4okw | 198 | Androgen receptor | / | 0.447 | |
| 4pkw | GM6 | Lethal factor | 3.4.24.83 | 0.447 | |
| 1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.446 | |
| 1gs4 | ZK5 | Androgen receptor | / | 0.446 | |
| 1gw2 | FER | Peroxidase C1A | 1.11.1.7 | 0.446 | |
| 1jtq | LY3 | Thymidylate synthase | / | 0.446 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.446 | |
| 2iws | NP4 | ATP-dependent molecular chaperone HSP82 | / | 0.446 | |
| 2uuj | 896 | Prothrombin | 3.4.21.5 | 0.446 | |
| 2uyw | BTN | Avd protein | / | 0.446 | |
| 2z4j | DHT | Androgen receptor | / | 0.446 | |
| 3dd1 | 25D | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.446 | |
| 3ed1 | GA3 | Gibberellin receptor GID1 | / | 0.446 | |
| 3g0y | P9A | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.446 | |
| 3jpu | TY4 | Transcriptional activator protein LasR | / | 0.446 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 4bmp | FMN | Protein NrdI | / | 0.446 | |
| 4eer | FMN | Phototropin-2 | 2.7.11.1 | 0.446 | |
| 4fwf | FAD | Lysine-specific histone demethylase 1B | 1 | 0.446 | |
| 4j52 | 1J3 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.446 | |
| 4kky | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.446 | |
| 4nyw | 2O3 | CREB-binding protein | / | 0.446 | |
| 4oed | DHT | Androgen receptor | / | 0.446 | |
| 1bvr | THT | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.445 | |
| 1ikg | REX | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.445 | |
| 1piw | NAP | NADP-dependent alcohol dehydrogenase 6 | 1.1.1.2 | 0.445 | |
| 1pvg | ANP | DNA topoisomerase 2 | 5.99.1.3 | 0.445 | |
| 1srh | MOB | Streptavidin | / | 0.445 | |
| 1w1w | AGS | Structural maintenance of chromosomes protein 1 | / | 0.445 | |
| 1wl4 | COA | Acetyl-CoA acetyltransferase, cytosolic | 2.3.1.9 | 0.445 | |
| 2a1m | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 2bxm | IMN | Serum albumin | / | 0.445 | |
| 2c31 | TZD | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.445 | |
| 2dv3 | SAH | Diphthine synthase | / | 0.445 | |
| 2huv | SAH | Diphthine synthase | / | 0.445 | |
| 2p5c | SAH | Diphthine synthase | / | 0.445 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.445 | |
| 2yki | YKI | Heat shock protein HSP 90-alpha | / | 0.445 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.445 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.445 | |
| 3keq | NAD | Redox-sensing transcriptional repressor Rex | / | 0.445 | |
| 3lt2 | FT3 | Enoyl-ACP reductase | / | 0.445 | |
| 3uxv | GUN | NADPH-dependent 7-cyano-7-deazaguanine reductase | / | 0.445 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.445 | |
| 4eh7 | IRG | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 4gt8 | ADP | Sensor protein VraS | 2.7.13.3 | 0.445 | |
| 4h4c | 10D | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase | / | 0.445 | |
| 4kou | C04 | Uncharacterized protein | / | 0.445 | |
| 4p6w | MOF | Glucocorticoid receptor | / | 0.445 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.445 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.445 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.444 | |
| 1h66 | RH1 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 1i91 | INQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.444 | |
| 1iwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 1opb | RET | Retinol-binding protein 2 | / | 0.444 | |
| 1orh | SAH | Protein arginine N-methyltransferase 1 | / | 0.444 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 1vzq | SHY | Prothrombin | 3.4.21.5 | 0.444 | |
| 1wxj | IPL | Tryptophan synthase alpha chain | / | 0.444 | |
| 1xud | PB4 | Collagenase 3 | 3.4.24 | 0.444 | |
| 2a4x | BLM | Mitomycin-binding protein | / | 0.444 | |
| 2c94 | TSF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.444 | |
| 2eh5 | SAH | Diphthine synthase | / | 0.444 | |
| 2fzb | TOL | Aldose reductase | 1.1.1.21 | 0.444 | |
| 2j9l | ATP | H(+)/Cl(-) exchange transporter 5 | / | 0.444 | |
| 2rgo | FAD | Alpha-Glycerophosphate Oxidase | / | 0.444 | |
| 2wd9 | IBP | Acyl-coenzyme A synthetase ACSM2A, mitochondrial | 6.2.1.2 | 0.444 | |
| 2ylp | TES | Androgen receptor | / | 0.444 | |
| 3aiv | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic | 3.2.1.182 | 0.444 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3ful | 52D | Leukotriene A-4 hydrolase | 3.3.2.6 | 0.444 | |
| 3gyj | FAD | Cholesterol oxidase | 1.1.3.6 | 0.444 | |
| 3nhj | A2Z | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.444 | |
| 3o4r | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.444 | |
| 3oet | NAD | Erythronate-4-phosphate dehydrogenase | / | 0.444 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.444 | |
| 3u7l | UDB | Peptide deformylase | / | 0.444 | |
| 3v8t | 477 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.444 | |
| 3zgl | 10E | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase | / | 0.444 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 4heu | 15J | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 4iwq | 1FV | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.444 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.444 | |
| 4k6i | 9RA | Retinoic acid receptor RXR-alpha | / | 0.444 | |
| 4nvk | 2NY | Peroxidase | / | 0.444 | |
| 4x7u | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.444 | |
| 5d4u | SAM | Uncharacterized protein MJ0489 | / | 0.444 | |
| 5d5b | CAU | Beta-2 adrenergic receptor | / | 0.444 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.443 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 1kw8 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.443 | |
| 1mcz | RMN | Benzoylformate decarboxylase | 4.1.1.7 | 0.443 | |
| 1utt | CP8 | Macrophage metalloelastase | 3.4.24.65 | 0.443 | |
| 1ztq | 033 | Collagenase 3 | 3.4.24 | 0.443 | |
| 2bgi | FAD | NADPH:ferredoxin reductase | / | 0.443 | |
| 2gpj | FAD | Siderophore-interacting protein | / | 0.443 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2jlb | UDM | Uncharacterized protein | / | 0.443 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.443 | |
| 2ovm | AS0 | Progesterone receptor | / | 0.443 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 3a3y | OBN | Sodium/potassium-transporting ATPase subunit alpha | / | 0.443 | |
| 3c3e | FO1 | 2-phospho-L-lactate transferase | / | 0.443 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.443 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 3gjw | GJW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.443 | |
| 3nun | JMZ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.443 | |
| 3q5k | D1U | Heat shock protein 83-1 | / | 0.443 | |
| 3wtk | TH4 | Acetylcholine-binding protein | / | 0.443 | |
| 3zo4 | QWI | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.443 | |
| 4biw | ANP | Sensor histidine kinase CpxA | / | 0.443 | |
| 4dld | TZG | Glutamate receptor ionotropic, kainate 1 | / | 0.443 | |
| 4inb | 1F6 | Gag protein | / | 0.443 | |
| 4ise | 1FW | Glucokinase | 2.7.1.2 | 0.443 | |
| 4wh3 | ATP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.443 | |
| 4z1f | H71 | Heat shock protein 75 kDa, mitochondrial | / | 0.443 | |
| 1dg7 | WRB | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1ftl | DNQ | Glutamate receptor 2 | / | 0.442 | |
| 1h69 | ARH | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 1kw6 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.442 | |
| 1lkd | BP6 | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.442 | |
| 1rdt | 570 | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 1svg | I04 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.442 | |
| 1xow | R18 | Androgen receptor | / | 0.442 | |
| 1ypl | RA8 | Prothrombin | 3.4.21.5 | 0.442 | |
| 2c31 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.442 | |
| 2fk8 | SAM | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.442 | |
| 2in6 | 839 | Wee1-like protein kinase | 2.7.10.2 | 0.442 | |
| 2oax | SNL | Mineralocorticoid receptor | / | 0.442 | |
| 2owb | 626 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.442 | |
| 2p1v | 5TN | Retinoic acid receptor RXR-alpha | / | 0.442 | |
| 2xls | FAD | Putative flavin-containing monooxygenase | / | 0.442 | |
| 2y3p | SM8 | DNA gyrase subunit A | / | 0.442 | |
| 2yee | 2EC | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 3d9z | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.442 | |
| 3fr2 | 8CA | Fatty acid-binding protein, adipocyte | / | 0.442 | |
| 3ipq | 965 | Oxysterols receptor LXR-alpha | / | 0.442 | |
| 3ml8 | ML8 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 3mnp | DEX | Glucocorticoid receptor | / | 0.442 | |
| 3tp0 | FO5 | HTH-type transcriptional regulator EthR | / | 0.442 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 4c6z | TLE | 3-oxoacyl-ACP synthase | / | 0.442 | |
| 4eil | CB3 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.442 | |
| 4h6z | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.442 | |
| 4imf | SI3 | N-acetylneuraminate lyase | / | 0.442 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
| 4okx | 198 | Androgen receptor | / | 0.442 | |
| 4u9y | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.442 | |
| 4u15 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.442 | |
| 1bif | AGS | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 | 2.7.1.105 | 0.441 | |
| 1fpq | SAM | Isoliquiritigenin 2'-O-methyltransferase | / | 0.441 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1vza | UMP | Thymidylate synthase | / | 0.441 | |
| 2a9z | 26A | Adenosine kinase | 2.7.1.20 | 0.441 | |
| 2c42 | TPP | Pyruvate synthase | / | 0.441 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.441 | |
| 2cmf | F11 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 2cul | FAD | GidA-related protein | / | 0.441 | |
| 2izf | BTN | Streptavidin | / | 0.441 | |
| 2p6i | SAH | Diphthine synthase | / | 0.441 | |
| 2pk3 | GDD | GDP-6-deoxy-D-mannose reductase | / | 0.441 | |
| 2xke | WI2 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.441 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 2yjx | YJX | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 2z4s | ADP | Chromosomal replication initiator protein DnaA | / | 0.441 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 2zgx | 29U | Prothrombin | 3.4.21.5 | 0.441 | |
| 3a0i | AJI | Glucokinase | 2.7.1.2 | 0.441 | |
| 3c35 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.441 | |
| 3d76 | NBB | Pheromone-binding protein ASP1 | / | 0.441 | |
| 3ih0 | ANP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.441 | |
| 3inx | JZC | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 3pch | CHB | Protocatechuate 3,4-dioxygenase beta chain | 1.13.11.3 | 0.441 | |
| 3qgf | 46F | Genome polyprotein | 2.7.7.48 | 0.441 | |
| 3zbx | 6XE | Hepatocyte growth factor receptor | 2.7.10.1 | 0.441 | |
| 3zdi | UGJ | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.441 | |
| 3zv5 | BPY | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.441 | |
| 4ajf | F03 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 4cf7 | ADP | Adenylate kinase | / | 0.441 | |
| 4da6 | GA2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.441 | |
| 4deg | 0JJ | Hepatocyte growth factor receptor | 2.7.10.1 | 0.441 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.441 | |
| 4eji | 0QA | Cytochrome P450 2A13 | 1.14.14.1 | 0.441 | |
| 4eue | NAI | Trans-2-enoyl-CoA reductase [NADH] | / | 0.441 | |
| 4g31 | 0WH | Eukaryotic translation initiation factor 2-alpha kinase 3 | 2.7.11.1 | 0.441 | |
| 4hxn | 1A7 | Bromodomain-containing protein 4 | / | 0.441 | |
| 4iom | FOL | Formate--tetrahydrofolate ligase | / | 0.441 | |
| 4isg | 1FY | Glucokinase | 2.7.1.2 | 0.441 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.441 | |
| 4j7x | SAS | Sepiapterin reductase | 1.1.1.153 | 0.441 | |
| 4x7w | MVI | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.441 | |
| 5epe | SAH | Uncharacterized protein | / | 0.441 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.441 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.440 | |
| 1dis | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.440 | |
| 1jd0 | AZM | Carbonic anhydrase 12 | 4.2.1.1 | 0.440 | |
| 1mue | CDD | Prothrombin | 3.4.21.5 | 0.440 | |
| 1nhz | 486 | Glucocorticoid receptor | / | 0.440 | |
| 1nzq | 162 | Prothrombin | 3.4.21.5 | 0.440 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.440 | |
| 1r2j | FAD | FkbI | / | 0.440 | |
| 1til | ATP | Anti-sigma F factor | / | 0.440 | |
| 1udt | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.440 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 2g28 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.440 | |
| 2pdl | TOL | Aldose reductase | 1.1.1.21 | 0.440 | |
| 2qbn | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 2wi6 | ZZ6 | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 2zhf | 49U | Prothrombin | 3.4.21.5 | 0.440 | |
| 3a25 | SAM | tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase | / | 0.440 | |
| 3cr0 | 809 | Wee1-like protein kinase | 2.7.10.2 | 0.440 | |
| 3dd8 | 2C7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.440 | |
| 3dlp | 174 | 4-chlorobenzoyl CoA ligase | / | 0.440 | |
| 3fc6 | REA | Retinoic acid receptor RXR-alpha | / | 0.440 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.440 | |
| 3oia | A31 | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 3p17 | 99P | Prothrombin | 3.4.21.5 | 0.440 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.440 | |
| 3sl2 | ATP | Sensor histidine kinase WalK | / | 0.440 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.440 | |
| 4ej1 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 4ffr | ATP | Uncharacterized protein | / | 0.440 | |
| 4fkx | CDP | Nucleoside diphosphate kinase | / | 0.440 | |
| 4gll | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.440 | |
| 4i9i | 1DY | Tankyrase-1 | 2.4.2.30 | 0.440 | |
| 4ixg | IXG | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 4l4a | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 4l4b | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.440 | |
| 4qzs | JQ1 | Bromodomain-containing protein 4 | / | 0.440 | |
| 4u9a | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.440 | |
| 5c4f | UPG | Histo-blood group ABO system transferase | / | 0.440 | |
| 5cc9 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.440 |