sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1iki | REY | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1iki | REY | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 1.000 | |
| 1yqs | BSA | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.725 | |
| 1ikg | REX | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.638 | |
| 1pw1 | HEL | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.572 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.508 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.507 | |
| 1w34 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.502 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.501 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.500 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.500 | |
| 3o7b | SAH | Ribosomal RNA small subunit methyltransferase Nep1 | / | 0.500 | |
| 4i10 | 1BS | Beta-secretase 1 | 3.4.23.46 | 0.499 | |
| 4jic | FMN | GTN Reductase | / | 0.499 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.497 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.497 | |
| 4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.497 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.491 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.490 | |
| 4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.489 | |
| 2fut | H1S | Heparin and heparin-sulfate lyase | / | 0.487 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.486 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.486 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.485 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.485 | |
| 1cnf | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.484 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.484 | |
| 1qbq | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.484 | |
| 1qbq | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.484 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.483 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.482 | |
| 4gm4 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.482 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.481 | |
| 3axk | NDP | Ribulose bisphosphate carboxylase large chain | 4.1.1.39 | 0.481 | |
| 3g0y | P9A | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.481 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.481 | |
| 3rpe | FAD | Putative modulator of drug activity | / | 0.481 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.480 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.480 | |
| 4j4n | D44 | Peptidylprolyl isomerase | / | 0.480 | |
| 1d0l | BLG | Membrane-bound lytic murein transglycosylase B | 4.2.2.n1 | 0.479 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.479 | |
| 3m2v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.478 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.478 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.477 | |
| 2a5h | SAM | L-lysine 2,3-aminomutase | 5.4.3.2 | 0.477 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.477 | |
| 2ohv | NHL | Glutamate racemase | / | 0.476 | |
| 3t64 | DU3 | Deoxyuridine 5'-triphosphate nucleotidohydrolase | / | 0.476 | |
| 3toz | NAD | Shikimate dehydrogenase (NADP(+)) | / | 0.476 | |
| 4xbj | IN5 | Alanine racemase, biosynthetic | / | 0.476 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.475 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.475 | |
| 3gka | FMN | N-ethylmaleimide reductase | / | 0.475 | |
| 3ndc | SAH | Precorrin-4 C(11)-methyltransferase | 2.1.1.133 | 0.475 | |
| 4eu9 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.475 | |
| 4j0t | 6T9 | Beta-secretase 1 | 3.4.23.46 | 0.475 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.475 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.474 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.474 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.474 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.474 | |
| 1umk | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.474 | |
| 2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.474 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.474 | |
| 2hs6 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.474 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.474 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.474 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.474 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.473 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.473 | |
| 5eio | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.473 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.472 | |
| 3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.472 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.472 | |
| 4gcm | NAP | Thioredoxin reductase | 1.8.1.9 | 0.472 | |
| 4req | 5AD | Methylmalonyl-CoA mutase large subunit | 5.4.99.2 | 0.472 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.471 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.471 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.470 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.470 | |
| 3l3m | A92 | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.470 | |
| 1ta6 | 177 | Prothrombin | 3.4.21.5 | 0.469 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.469 | |
| 2wzw | NDP | Nitroreductase NfnB | / | 0.469 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.469 | |
| 3hlw | CE3 | Beta-lactamase | / | 0.469 | |
| 4f9g | C2E | Stimulator of interferon genes protein | / | 0.469 | |
| 4fgc | PQ0 | NADPH-dependent 7-cyano-7-deazaguanine reductase | 1.7.1.13 | 0.469 | |
| 5ein | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.469 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.468 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.468 | |
| 2vyq | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.468 | |
| 2w6z | L21 | Biotin carboxylase | 6.3.4.14 | 0.468 | |
| 3keq | NAD | Redox-sensing transcriptional repressor Rex | / | 0.468 | |
| 3p84 | FMN | Pentaerythritol tetranitrate reductase | / | 0.468 | |
| 3qgi | 33F | Genome polyprotein | 2.7.7.48 | 0.468 | |
| 3vjl | W94 | Dipeptidyl peptidase 4 | / | 0.468 | |
| 1r6u | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.467 | |
| 1zgi | 382 | Prothrombin | 3.4.21.5 | 0.467 | |
| 2jh5 | 895 | Prothrombin | 3.4.21.5 | 0.467 | |
| 1y7l | ASN_LEU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.466 | |
| 3zho | FMN | NAD(P)H dehydrogenase (quinone) | / | 0.466 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.466 | |
| 4usq | FAD | Pyridine nucleotide-disulfide oxidoreductase | / | 0.466 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.465 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.465 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.465 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.465 | |
| 3bxo | UPP | dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose | / | 0.465 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.465 | |
| 4ef4 | C2E | Stimulator of interferon genes protein | / | 0.465 | |
| 4gdc | NDP | UDP-galactopyranose mutase | / | 0.465 | |
| 4yj2 | GTP | Tubulin alpha-1B chain | / | 0.465 | |
| 4xnw | 2ID | P2Y purinoceptor 1 | / | 0.465 | |
| 1ra8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 2b4t | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.464 | |
| 2i3g | NAP | N-acetyl-gamma-glutamyl-phosphate reductase | 1.2.1.38 | 0.464 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.464 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.464 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.464 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.464 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.464 | |
| 4e2d | FMN | Dehydrogenase | / | 0.464 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.463 | |
| 1v3q | 2DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.463 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.463 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.463 | |
| 2xje | U5P | Cytosolic purine 5'-nucleotidase | 3.1.3.5 | 0.463 | |
| 4hyv | PEP | Pyruvate kinase 1 | 2.7.1.40 | 0.463 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.462 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.462 | |
| 2vj6 | VG5 | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.462 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.462 | |
| 3nut | SAH | Precorrin-3 methylase | / | 0.462 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.462 | |
| 1a9c | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.461 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.461 | |
| 1h36 | R88 | Squalene--hopene cyclase | 4.2.1.129 | 0.461 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.461 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.461 | |
| 2ofi | ADK | 3-methyladenine DNA glycosylase I | / | 0.461 | |
| 3wyc | NAP | Meso-diaminopimelate D-dehydrogenase | 1.4.1.16 | 0.461 | |
| 4cr8 | NAD | N-acylmannosamine 1-dehydrogenase | 1.1.1.233 | 0.461 | |
| 4eud | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.461 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.461 | |
| 1a8p | FAD | Ferredoxin--NADP reductase | / | 0.460 | |
| 1tll | FMN | Nitric oxide synthase, brain | 1.14.13.39 | 0.460 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.460 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.460 | |
| 4rvg | TYD | D-mycarose 3-C-methyltransferase | / | 0.460 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 1mbb | EEB | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.459 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.459 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.459 | |
| 2aq7 | TL5 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.459 | |
| 2b3d | FAD | Modulator of drug activity B | / | 0.459 | |
| 2hxz | H7J | Cathepsin S | 3.4.22.27 | 0.459 | |
| 2iib | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.459 | |
| 2j2p | SC2 | Ficolin-2 | / | 0.459 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.459 | |
| 3lqs | PSZ | D-alanine aminotransferase | 2.6.1.21 | 0.459 | |
| 3lzx | NAP | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.459 | |
| 4jay | NAP | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.459 | |
| 4lcj | NAD | C-terminal-binding protein 2 | / | 0.459 | |
| 1foa | UD1 | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | 2.4.1.101 | 0.458 | |
| 1j0x | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.458 | |
| 2hfu | MEV | Mevalonate kinase | / | 0.458 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.458 | |
| 2q85 | 973 | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.458 | |
| 2xiq | 5AD | Methylmalonyl-CoA mutase, mitochondrial | / | 0.458 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 3gvh | NAD | Malate dehydrogenase | / | 0.458 | |
| 3tr0 | 5GP | Guanylate kinase | / | 0.458 | |
| 4n4v | 2GY | Tankyrase-1 | 2.4.2.30 | 0.458 | |
| 4yfy | 0FX | VioF | / | 0.458 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.457 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.457 | |
| 1h6c | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.457 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.457 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.457 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.457 | |
| 1x27 | ASP_ASP_TYR_VAL_PTR | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.457 | |
| 1xva | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.457 | |
| 3dzk | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.457 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.457 | |
| 3i8p | 840 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.457 | |
| 3iqi | ASN_GLU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.457 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.457 | |
| 3tjl | FMN | NADPH dehydrogenase | / | 0.457 | |
| 4m5p | FMN | NADPH dehydrogenase | / | 0.457 | |
| 1iay | AVG | 1-aminocyclopropane-1-carboxylate synthase 2 | 4.4.1.14 | 0.456 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.456 | |
| 3kmx | G00 | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.456 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.456 | |
| 4tnz | TTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.456 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.455 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.455 | |
| 1sdw | IYT | Peptidyl-glycine alpha-amidating monooxygenase | 1.14.17.3 | 0.455 | |
| 1wng | SAH | Diphthine synthase | / | 0.455 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.455 | |
| 2ab8 | MTP | Adenosine kinase | 2.7.1.20 | 0.455 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.455 | |
| 2yd0 | BES | Endoplasmic reticulum aminopeptidase 1 | 3.4.11 | 0.455 | |
| 2zvb | SAH | Precorrin-3 C17-methyltransferase | / | 0.455 | |
| 3phj | DHK | Shikimate dehydrogenase (NADP(+)) | / | 0.455 | |
| 4brd | ANP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.455 | |
| 4rww | 2BA | Lmo2692 protein | / | 0.455 | |
| 4xr9 | NAD | CalS8 | / | 0.455 | |
| 4yp6 | NAP | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.455 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.454 | |
| 1pwy | AC2 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.454 | |
| 1tow | CRZ | Fatty acid-binding protein, adipocyte | / | 0.454 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.454 | |
| 2ilv | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.454 | |
| 3iqg | ASN_TRP_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.454 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 4b63 | NAP | L-ornithine N(5)-monooxygenase | / | 0.454 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.454 | |
| 4d89 | BXD | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 4to4 | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.454 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.453 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.453 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 2dft | ADP | Shikimate kinase | 2.7.1.71 | 0.453 | |
| 2e07 | SAH | Diphthine synthase | / | 0.453 | |
| 2e8u | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.453 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.453 | |
| 2xys | SY9 | Soluble acetylcholine receptor | / | 0.453 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.453 | |
| 4du6 | GTP | GTP cyclohydrolase 1 | / | 0.453 | |
| 4gg1 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.453 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.453 | |
| 4tqg | NDP | Putative dTDP-d-glucose 4 6-dehydratase | / | 0.453 | |
| 4djh | JDC | Kappa-type opioid receptor | / | 0.453 | |
| 1icq | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.452 | |
| 1j37 | X8Z | Angiotensin-converting enzyme | 3.4.15.1 | 0.452 | |
| 1qx4 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.452 | |
| 1tco | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.452 | |
| 1tco | FK5 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | 3.1.3.16 | 0.452 | |
| 1ypg | UIR | Prothrombin | 3.4.21.5 | 0.452 | |
| 2wzy | SQX | Soluble acetylcholine receptor | / | 0.452 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.452 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.452 | |
| 3gxf | IFM | Glucosylceramidase | 3.2.1.45 | 0.452 | |
| 3ryk | TYD | dTDP-4-dehydrorhamnose 3,5-epimerase | / | 0.452 | |
| 3t0i | SAH | Putative methyltransferase | / | 0.452 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.452 | |
| 4f32 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | / | 0.452 | |
| 4fiz | CUE | 17beta-hydroxysteroid dehydrogenase | / | 0.452 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.452 | |
| 4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.451 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 1uma | IN2 | Prothrombin | 3.4.21.5 | 0.451 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.451 | |
| 2gby | BRN | HTH-type transcriptional regulator QacR | / | 0.451 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.451 | |
| 2hs8 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.451 | |
| 2oc9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.451 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 3egk | M18 | Prothrombin | 3.4.21.5 | 0.451 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.451 | |
| 4de3 | DN8 | Beta-lactamase | / | 0.451 | |
| 4gdd | NAI | UDP-galactopyranose mutase | / | 0.451 | |
| 4rp8 | ASC | Ascorbate-specific PTS system EIIC component | / | 0.451 | |
| 1kvu | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.450 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.450 | |
| 1z41 | FMN | NADPH dehydrogenase | / | 0.450 | |
| 2emr | SAH | Diphthine synthase | / | 0.450 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.450 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.450 | |
| 3muo | ZPR | Prolyl endopeptidase | / | 0.450 | |
| 4de2 | DN3 | Beta-lactamase | / | 0.450 | |
| 4js1 | CTN | Beta-galactoside alpha-2,6-sialyltransferase 1 | 2.4.99.1 | 0.450 | |
| 4nvk | 2NY | Peroxidase | / | 0.450 | |
| 4w5k | PLP | Aspartate aminotransferase, mitochondrial | / | 0.450 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.449 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.449 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.449 | |
| 2gz7 | D3F | Orf1a polyprotein | / | 0.449 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.449 | |
| 2xvh | FAD | Putative flavin-containing monooxygenase | / | 0.449 | |
| 2y1t | DUD | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.449 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3eku | CY9 | Actin-5C | / | 0.449 | |
| 3m2u | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.449 | |
| 3opx | U5P | Suppressor of disruption of TFIIS | / | 0.449 | |
| 4a6n | FAD | TetX family tetracycline inactivation enzyme | / | 0.449 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.449 | |
| 4h6p | FMN | Chromate reductase | / | 0.449 | |
| 5cho | FAD | Flavin reductase | / | 0.449 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.448 | |
| 1j9z | FAD | NADPH--cytochrome P450 reductase | / | 0.448 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.448 | |
| 1npd | NAD | Quinate/shikimate dehydrogenase | / | 0.448 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.448 | |
| 1rct | NOS | Purine nucleoside phosphorylase | 2.4.2.1 | 0.448 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.448 | |
| 1ywg | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.448 | |
| 2dxi | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.448 | |
| 2ome | NAD | C-terminal-binding protein 2 | / | 0.448 | |
| 2w6q | OA5 | Biotin carboxylase | 6.3.4.14 | 0.448 | |
| 3gjw | GJW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.448 | |
| 3i0o | SMI | Spectinomycin phosphotransferase | / | 0.448 | |
| 3t2v | KKJ | Peptidoglycan recognition protein 1 | / | 0.448 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.448 | |
| 4fdu | IHS | Putative multiple inositol polyphosphate histidine phosphatase 1 | / | 0.448 | |
| 5dw6 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.448 | |
| 7req | 2CP | Methylmalonyl-CoA mutase large subunit | 5.4.99.2 | 0.448 | |
| 1a5b | IGP | Tryptophan synthase alpha chain | / | 0.447 | |
| 1m4i | COA | Aminoglycoside 2'-N-acetyltransferase | 2.3.1 | 0.447 | |
| 1o1s | 1NH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.447 | |
| 1v45 | 3DG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.447 | |
| 1w35 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.447 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.447 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.447 | |
| 2viy | VG3 | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.447 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.447 | |
| 3h2s | NDP | Putative NADH-flavin reductase | / | 0.447 | |
| 3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.447 | |
| 3lzw | NAP | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.447 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 5c1d | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.447 | |
| 5e5h | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.447 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.446 | |
| 1itz | TPP | Transketolase, chloroplastic | 2.2.1.1 | 0.446 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.446 | |
| 1owe | 675 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.446 | |
| 1ri1 | GTG | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.446 | |
| 2e8q | SAH | Diphthine synthase | / | 0.446 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.446 | |
| 2g26 | 3LG | Renin | 3.4.23.15 | 0.446 | |
| 2ggb | U17 | Methionine aminopeptidase | / | 0.446 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.446 | |
| 2y05 | RAL | Prostaglandin reductase 1 | / | 0.446 | |
| 2zcv | NDP | Quinone oxidoreductase 2 | 1.6.5.2 | 0.446 | |
| 2zhe | 13U | Prothrombin | 3.4.21.5 | 0.446 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.446 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.446 | |
| 3hyg | 099 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.446 | |
| 3k5f | AYH | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 3khu | UPG | UDP-glucose 6-dehydrogenase | 1.1.1.22 | 0.446 | |
| 3nub | UD0 | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.446 | |
| 3ou2 | SAH | SAM-dependent methyltransferase | / | 0.446 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.446 | |
| 4axa | RKD | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.446 | |
| 4fqs | LYA | Thymidylate synthase ThyA | / | 0.446 | |
| 4fuj | 1U9 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.446 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.446 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.446 | |
| 4l4f | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.446 | |
| 4qai | FMN | NADPH dehydrogenase | / | 0.446 | |
| 4rvd | SAM | D-mycarose 3-C-methyltransferase | / | 0.446 | |
| 1k4m | NAD | Nicotinate-nucleotide adenylyltransferase | 2.7.7.18 | 0.445 | |
| 1n95 | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.445 | |
| 1n95 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.445 | |
| 1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 1wxj | IPL | Tryptophan synthase alpha chain | / | 0.445 | |
| 1x2e | ATX | Proline iminopeptidase | 3.4.11.5 | 0.445 | |
| 1ydt | IQB | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.445 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.445 | |
| 2npi | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.445 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.445 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.445 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.445 | |
| 3hgs | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.445 | |
| 3ivg | FG5 | Pantothenate synthetase | 6.3.2.1 | 0.445 | |
| 3oad | LPO | Renin | 3.4.23.15 | 0.445 | |
| 3pka | Y02 | Methionine aminopeptidase 2 | / | 0.445 | |
| 3qbj | NXZ | Dipeptidyl peptidase 4 | / | 0.445 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.445 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.445 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 4k28 | NAD | Shikimate dehydrogenase family protein | / | 0.445 | |
| 4loi | 1YC | Stimulator of interferon genes protein | / | 0.445 | |
| 4rnu | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.445 | |
| 4rnv | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.445 | |
| 5cfp | C2E | Stimulator of interferon genes protein | / | 0.445 | |
| 1l2t | ATP | Uncharacterized ABC transporter ATP-binding protein MJ0796 | / | 0.444 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.444 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.444 | |
| 2a2c | ADP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.444 | |
| 2cnd | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.444 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.444 | |
| 2gg0 | U11 | Methionine aminopeptidase | / | 0.444 | |
| 2xuf | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 3c35 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.444 | |
| 3dme | FAD | Putative conserved exported protein | / | 0.444 | |
| 3hy9 | 098 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.444 | |
| 3pkd | Y10 | Methionine aminopeptidase 2 | / | 0.444 | |
| 3v2u | ATP | Protein GAL3 | / | 0.444 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 4nv1 | TYD | Formyl transferase | / | 0.444 | |
| 4to5 | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.444 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.444 | |
| 4xfj | ANP | Argininosuccinate synthase | / | 0.444 | |
| 5jy1 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.444 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.443 | |
| 1dgm | ADN | Adenosine kinase | 2.7.1.20 | 0.443 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.443 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.443 | |
| 1p4a | PCP | Pur operon repressor | / | 0.443 | |
| 1q45 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.443 | |
| 1qpl | 587 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.443 | |
| 1s63 | 778 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.443 | |
| 1udb | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.443 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.443 | |
| 2dsg | SAH | Diphthine synthase | / | 0.443 | |
| 2g21 | L1B | Renin | 3.4.23.15 | 0.443 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.443 | |
| 2zs8 | ADP | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.443 | |
| 3mau | EXT | Putative sphingosine-1-phosphate lyase | / | 0.443 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.443 | |
| 4acu | QN7 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 4djx | 0KQ | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4fm8 | 0UQ | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.443 | |
| 4jnk | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.443 | |
| 4lxk | 1YT | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.443 | |
| 4ypu | SAM | Histone-lysine N-methyltransferase ASH1L | 2.1.1.43 | 0.443 | |
| 5ao1 | DG3 | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.443 | |
| 1a9z | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.442 | |
| 1e7q | NAP | GDP-L-fucose synthase | / | 0.442 | |
| 1ivs | VAA | Valine--tRNA ligase | 6.1.1.9 | 0.442 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.442 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 1ppj | ANY | Cytochrome b | / | 0.442 | |
| 1rkw | PNT | HTH-type transcriptional regulator QacR | / | 0.442 | |
| 1tou | B1V | Fatty acid-binding protein, adipocyte | / | 0.442 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.442 | |
| 2dfv | NAD | L-threonine 3-dehydrogenase | / | 0.442 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.442 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.442 | |
| 2pbw | DOQ | Glutamate receptor ionotropic, kainate 1 | / | 0.442 | |
| 2qc8 | ADP | Glutamine synthetase | 6.3.1.2 | 0.442 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.442 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.442 | |
| 4ax9 | N5N | Prothrombin | 3.4.21.5 | 0.442 | |
| 4c72 | TLG | 3-oxoacyl-ACP synthase | / | 0.442 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.442 | |
| 4e2b | FMN | Dehydrogenase | / | 0.442 | |
| 4kgk | GTP | Uncharacterized protein | / | 0.442 | |
| 4rvf | TYD | D-mycarose 3-C-methyltransferase | / | 0.442 | |
| 4z26 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.442 | |
| 1mew | XMP | Inosine-5'-monophosphate dehydrogenase | / | 0.441 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.441 | |
| 1trk | TPP | Transketolase 1 | 2.2.1.1 | 0.441 | |
| 1uxy | EPU | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.441 | |
| 2aqb | TL6 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.441 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.441 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.441 | |
| 2q3r | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.441 | |
| 3cty | FAD | Probable thioredoxin reductase | / | 0.441 | |
| 3dzi | RGT | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.441 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.441 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.441 | |
| 3kji | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.441 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.441 | |
| 3pm1 | ET | HTH-type transcriptional regulator QacR | / | 0.441 | |
| 4ddh | MS0 | Pantothenate synthetase | 6.3.2.1 | 0.441 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.441 | |
| 4mpr | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.441 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.441 | |
| 5ah5 | LSS | Leucine--tRNA ligase | / | 0.441 | |
| 5cfl | C2E | Stimulator of interferon genes protein | / | 0.441 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.440 | |
| 1cs4 | FOK | Adenylate cyclase type 2 | / | 0.440 | |
| 1cs4 | FOK | Adenylate cyclase type 5 | / | 0.440 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.440 | |
| 1gvr | TNL | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 1h62 | ANB | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 1jol | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1opm | IYG | Peptidyl-glycine alpha-amidating monooxygenase | 1.14.17.3 | 0.440 | |
| 1ulb | GUN | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 2cmo | M1L | Glutamate receptor 2 | / | 0.440 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 2zsi | GA4 | Gibberellin receptor GID1A | 3 | 0.440 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.440 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.440 | |
| 3g0c | RUF | Dipeptidyl peptidase 4 | / | 0.440 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.440 | |
| 3ojx | FMN | NADPH--cytochrome P450 reductase | / | 0.440 | |
| 4b64 | NAP | L-ornithine N(5)-monooxygenase | / | 0.440 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.440 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.440 | |
| 4gv7 | MEW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.440 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.440 | |
| 4kp8 | E1G | Carbonic anhydrase 12 | 4.2.1.1 | 0.440 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.440 | |
| 4oi4 | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.440 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.440 | |
| 4qnw | FMN | Chanoclavine-I aldehyde reductase easA | / | 0.440 | |
| 5czy | SAM | Eukaryotic huntingtin interacting protein B | / | 0.440 |