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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1ecb5GPAmidophosphoribosyltransferase

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
1ecb5GPAmidophosphoribosyltransferase/1.000
3q9bB3NAcetylpolyamine amidohydrolase/0.551
4b68NAPL-ornithine N(5)-monooxygenase/0.517
3cgtBCDCyclomaltodextrin glucanotransferase2.4.1.190.505
5czySAMEukaryotic huntingtin interacting protein B/0.501
2f3rG5PGuanylate kinase2.7.4.80.498
2pncCLUPrimary amine oxidase, liver isozyme/0.498
4gz612VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.498
1ni4TPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.496
1ni4TPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.496
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.496
2dvoITTdITP/XTP pyrophosphatase3.6.1.190.493
3ry2BTNStreptavidin/0.491
4dan2FAPurine nucleoside phosphorylase DeoD-type2.4.2.10.491
4jzr4JREgl nine homolog 1/0.491
4xczT3QQdtf/0.491
1n4pCYS_VAL_ILE_LEU_GERGeranylgeranyl transferase type-1 subunit beta2.5.1.590.489
4briUNPEctonucleoside triphosphate diphosphohydrolase I/0.489
1ao05GPAmidophosphoribosyltransferase/0.488
2fhnBNIAvidin-related protein 4/5/0.488
3ndjJHZMethyltransferase/0.487
3af3GCPPantothenate kinase2.7.1.330.485
4q4kFMNUncharacterized protein/0.485
2a0yDIHPurine nucleoside phosphorylase2.4.2.10.484
2izfBTNStreptavidin/0.484
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.484
3tjlFMNNADPH dehydrogenase/0.483
2r8oT5XTransketolase 1/0.482
4j7hTRHPCZA361.3/0.481
2g1n1IGRenin3.4.23.150.480
2vkeTACTetracycline repressor protein class D/0.480
3eq02TSProthrombin3.4.21.50.480
1pq944BOxysterols receptor LXR-beta/0.479
2pk3A2RGDP-6-deoxy-D-mannose reductase/0.479
1s3uTQDDihydrofolate reductase1.5.1.30.478
4ubvCOASteroid 3-ketoacyl-CoA thiolase/0.478
1ngsTPPTransketolase 12.2.1.10.477
2bfmTOPPteridine reductase 11.5.1.330.477
2flhZEACytokinin-specific binding protein/0.477
3gu3SAHMethyltransferase/0.477
4jeyPLPAcetylornithine/succinyldiaminopimelate aminotransferase2.6.1.110.477
1rt9IMHPurine nucleoside phosphorylase2.4.2.10.476
2v58LZJBiotin carboxylase6.3.4.140.476
2zatNAPDehydrogenase/reductase SDR family member 41.1.1.1840.476
4kxjP34Nucleoprotein/0.476
1s20NAD2,3-diketo-L-gulonate reductase1.1.1.1300.475
3fhxPLPPyridoxal kinase2.7.1.350.475
3t2wBTNAvidin/streptavidin/0.475
4bqzGNPEctonucleoside triphosphate diphosphohydrolase 2/0.475
4xxvNAD3-isopropylmalate dehydrogenase/0.475
4n3l2FNProthrombin3.4.21.50.474
1gpuTHDTransketolase 12.2.1.10.473
3i2834NBifunctional epoxide hydrolase 23.3.2.100.473
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.473
4yddMD1DMSO reductase family type II enzyme, molybdopterin subunit/0.473
1b2lNDCAlcohol dehydrogenase1.1.1.10.472
1e2nRCAThymidine kinase/0.472
1k4mNADNicotinate-nucleotide adenylyltransferase2.7.7.180.471
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.471
3fhxPXLPyridoxal kinase2.7.1.350.471
4f0e0RUPoly [ADP-ribose] polymerase 152.4.2.300.471
1rxhBNIStreptavidin/0.470
3g0cRUFDipeptidyl peptidase 4/0.470
4xd1T3QQdtf/0.469
1ndjBTNStreptavidin/0.468
1rszDIHPurine nucleoside phosphorylase2.4.2.10.468
1yw8A75Methionine aminopeptidase 2/0.468
2aviBTNAvidin/0.468
2ed4NAD4-hydroxyphenylacetate 3-monooxygenase reductase component1.5.1.360.468
2fjdSFDAdenylylsulfate reductase, subunit A (AprA)/0.468
2q7oIMHPurine nucleoside phosphorylase2.4.2.10.468
3b9xNOSPyrimidine-specific ribonucleoside hydrolase RihB3.2.2.80.468
3pftFMNFlavin reductase/0.468
3qvpFADGlucose oxidase1.1.3.40.468
4b63NAPL-ornithine N(5)-monooxygenase/0.468
4bfxZVXPantothenate kinase2.7.1.330.468
5dp2NAPCurF/0.468
1h50FMNPentaerythritol tetranitrate reductase/0.467
1lcwSHMStreptavidin/0.467
1qx4FADNADH-cytochrome b5 reductase 31.6.2.20.467
1t57FMNConserved protein/0.467
4jlm1NNDeoxycytidine kinase2.7.1.740.467
5bt9NAP3-oxoacyl-(Acyl-carrier-protein) reductase/0.467
1jjeBYSBeta-lactamase/0.466
2b36NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.466
2cftPLPPyridoxal phosphate phosphatase/0.466
2yg4FADPutrescine oxidase/0.466
4l1xNAPAldo-keto reductase family 1 member C2/0.466
2nmtMIMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.465
2nnqT4BFatty acid-binding protein, adipocyte/0.465
2qo9ANPEphrin type-A receptor 32.7.10.10.465
2vcmM11Isopenicillin N synthase1.21.3.10.465
3bi6396Wee1-like protein kinase2.7.10.20.465
3fktSIIBeta-secretase 13.4.23.460.465
3isjA8DPantothenate synthetase6.3.2.10.465
3nmpPYVAbscisic acid receptor PYL2/0.465
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.465
4p9dTMPDeoxycytidylate deaminase/0.465
4wrkDUPDUTPase/0.465
6req3CPMethylmalonyl-CoA mutase large subunit5.4.99.20.465
2gesCOKPantothenate kinase2.7.1.330.464
2q1tNADPutative nucleotide sugar epimerase/ dehydratase/0.464
3dmeFADPutative conserved exported protein/0.464
3dvaTPWPyruvate dehydrogenase E1 component subunit alpha1.2.4.10.464
3dvaTPWPyruvate dehydrogenase E1 component subunit beta1.2.4.10.464
4yekTHMThymidine phosphorylase/0.464
1gj5130Prothrombin3.4.21.50.463
2gvdFKPAdenylate cyclase type 2/0.463
2gvdFKPAdenylate cyclase type 5/0.463
2jbsFMNp-hydroxyphenylacetate 3-hydroxylase, oxygenase component/0.463
2r5nTPPTransketolase 1/0.463
2x9dITCTetracycline repressor protein class D/0.463
2zsbADPPantothenate kinase2.7.1.330.463
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.463
3zeiAWHO-acetylserine sulfhydrylase/0.463
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.463
4l4fCAMCamphor 5-monooxygenase1.14.15.10.463
4nmdFDABifunctional protein PutA/0.463
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.463
1xgjHTCBeta-lactamase3.5.2.60.462
2wf3ZY3Beta-secretase 13.4.23.460.462
3dhbC6LN-acyl homoserine lactonase AiiA3.1.1.810.462
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.462
2a0wDIHPurine nucleoside phosphorylase2.4.2.10.461
2ag5NAD3-hydroxybutyrate dehydrogenase type 2/0.461
2geuCOKPantothenate kinase2.7.1.330.461
2wggTLM3-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.461
2zseACPPantothenate kinase2.7.1.330.461
3to3ATPPetrobactin biosynthesis protein AsbB/0.461
4iqgNAPShort-chain dehydrogenase/reductase SDR/0.461
4rlh0WEEnoyl-[acyl-carrier-protein] reductase [NADH]/0.461
5c4cUPGHisto-blood group ABO system transferase/0.461
3aosJH2Hemolymph juvenile hormone binding protein/0.460
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.460
1cjvFOKAdenylate cyclase type 2/0.459
1cjvFOKAdenylate cyclase type 5/0.459
1kiaSAMGlycine N-methyltransferase2.1.1.200.459
2izkGLLStreptavidin/0.459
2o12FMNChorismate synthase/0.459
3h2sNDPPutative NADH-flavin reductase/0.459
3wdsNADNADH-dependent quinuclidinone reductase/0.459
4br0AU1Ectonucleoside triphosphate diphosphohydrolase 2/0.459
1q84TZ4Acetylcholinesterase3.1.1.70.458
1ycfFMNNitric oxide reductase10.458
2pakTYDTDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase5.3.2.30.458
2xpuTDCTetracycline repressor protein class D/0.458
3autNAIGlucose 1-dehydrogenase 41.1.1.470.458
3ed1GA3Gibberellin receptor GID1/0.458
3exhTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.458
3exhTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.458
3ozc4CTS-methyl-5'-thioadenosine phosphorylase/0.458
3wznBTNStreptavidin/0.458
1p0pBCHCholinesterase3.1.1.80.457
1ppjANYCytochrome b/0.457
1u5cBIKL-lactate dehydrogenase1.1.1.270.457
1yciNDFHypoxia-inducible factor 1-alpha inhibitor1.14.11.300.457
2iibC5PAlpha-2,3/2,6-sialyltransferase/sialidase/0.457
4ggzBTNBll1558 protein/0.457
1nzq162Prothrombin3.4.21.50.456
1tduCB3Thymidylate synthase/0.456
2bf7HBIPteridine reductase 11.5.1.330.456
2fj1CTCTetracycline repressor protein class D/0.456
2pg0FADAcyl-CoA dehydrogenase/0.456
2r8pT6FTransketolase 1/0.456
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.456
3c1kT15Prothrombin3.4.21.50.456
3juoAJDPhenazine biosynthesis protein A/B/0.456
3mauPLRPutative sphingosine-1-phosphate lyase/0.456
4m0cFMNFMN-dependent NADH-azoreductase 1/0.456
4m5pFMNNADPH dehydrogenase/0.456
1f4fTP3Thymidylate synthase/0.455
1h5qNAPNADP-dependent mannitol dehydrogenase1.1.1.1380.455
1o2g696Prothrombin3.4.21.50.455
1pqc444Oxysterols receptor LXR-beta/0.455
1qrsATPGlutamine--tRNA ligase6.1.1.180.455
2z52H23Geranylgeranyl pyrophosphate synthase/0.455
3arvSAUChitinase A/0.455
3bgsDIHPurine nucleoside phosphorylase2.4.2.10.455
3p0hFSEPutative tyrosyl-tRNA synthetase/0.455
4bamMM9Prothrombin3.4.21.50.455
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.455
4fhd0TTSpore photoproduct lyase/0.455
4hmz18TdTDP-4-dehydro-6-deoxyglucose 3-epimerase5.1.3.270.455
4i4z2NE1,4-dihydroxy-2-naphthoyl-CoA synthase/0.455
4mr72BVGamma-aminobutyric acid type B receptor subunit 1/0.455
4twnB96Ephrin type-A receptor 32.7.10.10.455
3sn6P0GBeta-2 adrenergic receptor/0.455
1h61PDNPentaerythritol tetranitrate reductase/0.454
1tduDURThymidylate synthase/0.454
1txtCAAHMG-CoA synthase/0.454
1v35NAIEnoyl-ACP reductase/0.454
1w76GNTAcetylcholinesterase3.1.1.70.454
2ea4F79Methionine aminopeptidase 2/0.454
2g28TDKPyruvate dehydrogenase E1 component1.2.4.10.454
2o7pNAPRiboflavin biosynthesis protein RibD/0.454
2y60M8FIsopenicillin N synthase1.21.3.10.454
3ansS38Bifunctional epoxide hydrolase 23.3.2.100.454
4an4DUDPutative glycosyl transferase/0.454
4df2FMNNADPH dehydrogenase/0.454
4emdC5P4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.454
4jnkZHKL-lactate dehydrogenase A chain1.1.1.270.454
4psbGA3Cytokinin-specific binding protein/0.454
1a4wQWEProthrombin3.4.21.50.453
1df8BTNStreptavidin/0.453
1kicNOSIAG-nucleoside hydrolase/0.453
1re0AFBADP-ribosylation factor 1/0.453
1re0AFBARF guanine-nucleotide exchange factor 1/0.453
1stpBTNStreptavidin/0.453
1yryMSGPurine nucleoside phosphorylase2.4.2.10.453
1zp4FAD5,10-methylenetetrahydrofolate reductase1.5.1.200.453
2a1hGBNBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.453
2ftoTMPThymidylate synthase/0.453
2p9gNAID-3-phosphoglycerate dehydrogenase1.1.1.950.453
3akn11DFatty acid-binding protein, intestinal/0.453
3ko8NADNAD-dependent epimerase/dehydratase/0.453
3ll9ADPIsopentenyl phosphate kinase/0.453
3zkuHCVIsopenicillin N synthase1.21.3.10.453
4araC56Acetylcholinesterase3.1.1.70.453
1h2bNAJNAD-dependent alcohol dehydrogenase/0.452
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.452
1sdmADPKinesin heavy chain-like protein/0.452
1tilATPAnti-sigma F factor/0.452
1v2hGUNPurine nucleoside phosphorylase2.4.2.10.452
1wsbFMNFlavodoxin/0.452
1wxjIPLTryptophan synthase alpha chain/0.452
1x1cSAHC-20 methyltransferase/0.452
2abbFMNPentaerythritol tetranitrate reductase/0.452
2b35NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.452
2vkvTDCTetracycline repressor protein class D/0.452
2vprTDCTetracycline repressor protein class H/0.452
2zscBTNTamavidin2/0.452
3ggs2FDPurine nucleoside phosphorylase2.4.2.10.452
3klbFMNUncharacterized protein/0.452
4dbzNDPPutative ketoacyl reductase1.3.10.452
4n3cUD1UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.452
4rjeFNRLactate oxidase/0.452
1culFOKAdenylate cyclase type 2/0.451
1culFOKAdenylate cyclase type 5/0.451
1g0rTHMGlucose-1-phosphate thymidylyltransferase/0.451
1gjrFADFerredoxin--NADP reductase1.18.1.20.451
1gky5GPGuanylate kinase2.7.4.80.451
1icsFMN12-oxophytodienoate reductase 11.3.1.420.451
1t4u81AProthrombin3.4.21.50.451
3cb2GDPTubulin gamma-1 chain/0.451
3djfBC3Purine nucleoside phosphorylase/0.451
3dwbRDFEndothelin-converting enzyme 13.4.24.710.451
3h3sH15Collagen type IV alpha-3-binding protein/0.451
3r43ID8Aldo-keto reductase family 1 member C3/0.451
4adcPLPSuccinylornithine transaminase2.6.1.810.451
4mr92BXGamma-aminobutyric acid type B receptor subunit 1/0.451
5fm7ADPRuvB-like helicase/0.451
1kqoDNDNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.450
1mvtDTMDihydrofolate reductase1.5.1.30.450
1n2vBDIQueuine tRNA-ribosyltransferase2.4.2.290.450
1rr6IMHPurine nucleoside phosphorylase2.4.2.10.450
1zrb062Prothrombin3.4.21.50.450
2hzqSTRApolipoprotein D/0.450
2oc9IMHPurine nucleoside phosphorylase2.4.2.10.450
2vkmBSDBeta-secretase 13.4.23.460.450
2wd8VGFPteridine reductase/0.450
3c3xNAPEugenol synthase 11.1.1.3180.450
3dz7O8MS-adenosylmethionine decarboxylase proenzyme4.1.1.500.450
3exfTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.450
3exfTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.450
3gonANPPhosphomevalonate kinase/0.450
3p8iFMNPentaerythritol tetranitrate reductase/0.450
3pqbVGPPutative oxidoreductase/0.450
3rsv3RSBeta-secretase 13.4.23.460.450
3zbsOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.450
4b66NAPL-ornithine N(5)-monooxygenase/0.450
4bc7FADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.450
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.450
4gyy12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.450
4lb2DM5Serum albumin/0.450
4q0kGA3Phytohormone-binding protein/0.450
1n5dNDPCarbonyl reductase [NADPH] 1/0.449
2o4gTMPThree-prime repair exonuclease 13.1.11.20.449
2v5aLZLBiotin carboxylase6.3.4.140.449
2vceU2FUDP-glycosyltransferase 72B1/0.449
2wmdZZ0NmrA-like family domain-containing protein 1/0.449
2yutNAPPutative short-chain oxidoreductase/0.449
3g0bT22Dipeptidyl peptidase 4/0.449
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.449
3nytULPUDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase2.6.1.980.449
3ojxFMNNADPH--cytochrome P450 reductase/0.449
3ov7ATPCCA-adding enzyme2.7.7.720.449
3tfyCOAN-alpha-acetyltransferase 502.3.10.449
4l4eCAMCamphor 5-monooxygenase1.14.15.10.449
4uwmFMN3,6-diketocamphane 1,6 monooxygenase1.14.130.449
5c3aURMHisto-blood group ABO system transferase/0.449
1ay0TPPTransketolase 12.2.1.10.448
1dgmADNAdenosine kinase2.7.1.200.448
1g63FMNEpidermin decarboxylase4.1.10.448
1kr2TADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.448
2e07SAHDiphthine synthase/0.448
2ea1GPGRibonuclease I3.1.27.60.448
2ea2F77Methionine aminopeptidase 2/0.448
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.448
2wf1ZY1Beta-secretase 13.4.23.460.448
3tfyMET_LEU_GLY_PRON-alpha-acetyltransferase 502.3.10.448
3zxiTYATyrosine--tRNA ligase, mitochondrial6.1.1.10.448
4e2xTYDMethyltransferase/0.448
4xnw2IDP2Y purinoceptor 1/0.448
1a9p9DIPurine nucleoside phosphorylase2.4.2.10.447
1b5eDCMDeoxycytidylate 5-hydroxymethyltransferase2.1.2.80.447
1kt8ILPBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.447
1oc1ASVIsopenicillin N synthase1.21.3.10.447
1ykgFMNSulfite reductase [NADPH] flavoprotein alpha-component/0.447
2abjPLPBranched-chain-amino-acid aminotransferase, cytosolic2.6.1.420.447
2f99AKVAklanonic acid methyl ester cyclase AcmA5.5.1.230.447
2pb6SAHDiphthine synthase/0.447
2q9fC3SCholesterol 24-hydroxylase/0.447
2ztuNADD(-)-3-hydroxybutyrate dehydrogenase/0.447
3fsjD7KBenzoylformate decarboxylase4.1.1.70.447
3k8o229Purine nucleoside phosphorylase2.4.2.10.447
3qwc98PProthrombin3.4.21.50.447
4b79NADProbable short-chain dehydrogenase/0.447
4bkqNAIEnoyl-[acyl-carrier-protein] reductase [NADH]/0.447
4dc0NDPPutative ketoacyl reductase1.3.10.447
4fx2FMNFlavodoxin/0.447
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.447
4k6fNAPPutative Acetoacetyl-CoA reductase/0.447
4locBTNPyruvate carboxylase/0.447
4rnwFMNNADPH dehydrogenase 11.6.99.10.447
1b8nIMGPurine nucleoside phosphorylase2.4.2.10.446
1cs4FOKAdenylate cyclase type 2/0.446
1cs4FOKAdenylate cyclase type 5/0.446
1d3dBZTProthrombin3.4.21.50.446
1tkaN3TTransketolase 12.2.1.10.446
1u0hFOKAdenylate cyclase type 2/0.446
1u0hFOKAdenylate cyclase type 5/0.446
2a0xDIHPurine nucleoside phosphorylase2.4.2.10.446
2bpoFADNADPH--cytochrome P450 reductase/0.446
2ed3SAHDiphthine synthase/0.446
2ekaSAHDiphthine synthase/0.446
2g25TDKPyruvate dehydrogenase E1 component1.2.4.10.446
2r2mI50Prothrombin3.4.21.50.446
2rm2W43Genome polyprotein/0.446
2wo7ASVIsopenicillin N synthase1.21.3.10.446
2xvhNAPPutative flavin-containing monooxygenase/0.446
2zhe13UProthrombin3.4.21.50.446
3ekuCY9Actin-5C/0.446
3elePLPAminotransferase/0.446
3fr5I4AFatty acid-binding protein, adipocyte/0.446
3imeBZ2Pantothenate synthetase6.3.2.10.446
3ohh3HHBeta-secretase 13.4.23.460.446
3sqxANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.446
3tklGTPRas-related protein Rab-1A/0.446
4jayNAPUDP-N-acetylenolpyruvoylglucosamine reductase/0.446
4nwiCTN7-methylguanosine phosphate-specific 5'-nucleotidase/0.446
4zzi1NSNAD-dependent protein deacetylase sirtuin-13.5.10.446
5ayaX8ZMetallo-beta-lactamase/0.446
1enoNADEnoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic1.3.1.90.445
1hkuNADC-terminal-binding protein 11.1.10.445
1obnASVIsopenicillin N synthase1.21.3.10.445
1pj6FOLDimethylglycine oxidase1.5.3.100.445
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.445
1rfgGMPPurine nucleoside phosphorylase2.4.2.10.445
2a9z26AAdenosine kinase2.7.1.200.445
2e8qSAHDiphthine synthase/0.445
2rd2QSIGlutamine--tRNA ligase6.1.1.180.445
2wnsOMPUridine 5'-monophosphate synthase2.4.2.100.445
2xlpNAPPutative flavin-containing monooxygenase/0.445
2xugTZ4Acetylcholinesterase3.1.1.70.445
2xujTZ5Acetylcholinesterase3.1.1.70.445
2zevIPEGeranylgeranyl pyrophosphate synthase/0.445
3aezGDPPantothenate kinase2.7.1.330.445
3b1dPLSBetaC-S lyase/0.445
3gwdNAPCyclohexanone monooxygenase/0.445
3iifAPRCore histone macro-H2A.1/0.445
3uxvGUNNADPH-dependent 7-cyano-7-deazaguanine reductase/0.445
4e32DWNMethyltransferase/0.445
4ek1CAMCamphor 5-monooxygenase1.14.15.10.445
4zu44TGWxcM-like protein/0.445
5js6NAD17-beta-hydroxysteroid dehydrogenase 141.1.10.445
7catNDPCatalase1.11.1.60.445
1ib0FADNADH-cytochrome b5 reductase 31.6.2.20.444
1k02FMNNADPH dehydrogenase 11.6.99.10.444
1qs2NADVip2Ac/0.444
1tl7FOKAdenylate cyclase type 2/0.444
1tl7FOKAdenylate cyclase type 5/0.444
1udaUFGUDP-glucose 4-epimerase5.1.3.20.444
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.444
2pk3GDDGDP-6-deoxy-D-mannose reductase/0.444
2qtrNXXProbable nicotinate-nucleotide adenylyltransferase/0.444
2xk4OL2Serine/threonine-protein kinase Nek22.7.11.10.444
2zsiGA4Gibberellin receptor GID1A30.444
2zuiCAMCamphor 5-monooxygenase1.14.15.10.444
3af2ACPPantothenate kinase2.7.1.330.444
3c1oNAPEugenol synthase/0.444
3gfbNADL-threonine 3-dehydrogenase/0.444
3iobA4DPantothenate synthetase6.3.2.10.444
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
3o3jBB4Peptide deformylase 1B, chloroplastic/mitochondrial3.5.1.880.444
3p62FMNPentaerythritol tetranitrate reductase/0.444
3up0D7SaceDAF-12/0.444
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.444
3zkyWT4Isopenicillin N synthase1.21.3.10.444
4esoNAPPutative oxidoreductase/0.444
4hkfACOAlpha-tubulin N-acetyltransferase 1/0.444
4r1lADPPhenylacetate-coenzyme A ligase/0.444
4tmcFMNOld yellow enzyme/0.444
4u3jGTPTubulin beta chain/0.444
5eghPCEctonucleotide pyrophosphatase/phosphodiesterase family member 6/0.444
1afeALZProthrombin3.4.21.50.443
1kh3ANPArgininosuccinate synthase/0.443
1mueCDDProthrombin3.4.21.50.443
1piwNAPNADP-dependent alcohol dehydrogenase 61.1.1.20.443
1rpnNDPGDP-mannose 4,6-dehydratase/0.443
1z6tADPApoptotic protease-activating factor 1/0.443
1zxmANPDNA topoisomerase 2-alpha5.99.1.30.443
2pdtFADVivid PAS protein VVD/0.443
2pzjNADPutative nucleotide sugar epimerase/ dehydratase/0.443
2uupLK4UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.443
3bxoUPPdTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose/0.443
3c27DKKProthrombin3.4.21.50.443
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.443
3qj0QI3Botulinum neurotoxin type A3.4.24.690.443
3ziuLSSLeucyl-tRNA synthetase/0.443
4b64NAPL-ornithine N(5)-monooxygenase/0.443
4bftZVTPantothenate kinase2.7.1.330.443
4brgGNPEctonucleoside triphosphate diphosphohydrolase I/0.443
4eagATP5'-AMP-activated protein kinase subunit gamma-1/0.443
4g8jTHMUridine phosphorylase/0.443
4u0sADPAdenosine monophosphate-protein transferase FICD2.7.7.n10.443
5jsfNAD17-beta-hydroxysteroid dehydrogenase 141.1.10.443
1fxuGU7Purine nucleoside phosphorylase2.4.2.10.442
1h51FMNPentaerythritol tetranitrate reductase/0.442
1h63FMNPentaerythritol tetranitrate reductase/0.442
1ju9NADAlcohol dehydrogenase E chain1.1.1.10.442
1odnAPVIsopenicillin N synthase1.21.3.10.442
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.442
1uhoVDNcGMP-specific 3',5'-cyclic phosphodiesterase/0.442
1vftDCSAlanine racemase/0.442
1yplRA8Prothrombin3.4.21.50.442
1zx1CB1Ribosyldihydronicotinamide dehydrogenase [quinone]/0.442
2hs6FMN12-oxophytodienoate reductase 31.3.1.420.442
2jgsBTNAvidin/0.442
2xviFADPutative flavin-containing monooxygenase/0.442
3f03FMNPentaerythritol tetranitrate reductase/0.442
3fun798Leukotriene A-4 hydrolase3.3.2.60.442
3o26NDPSalutaridine reductase/0.442
3p2kSAM16S rRNA (adenine(1408)-N(1))-methyltransferase2.1.1.1800.442
3tleGSUMicrocin C7 self-immunity protein MccF/0.442
4a86H35Major pollen allergen Bet v 1-A/0.442
4bfsZVSPantothenate kinase2.7.1.330.442
4cf6CBDNAD(P)H dehydrogenase [quinone] 11.6.5.20.442
4dz5NAPAldo-keto reductase family 1 member C3/0.442
4i8vBHFCytochrome P450 1A11.14.14.10.442
4i9n1E5L-lactate dehydrogenase A chain1.1.1.270.442
4iarERM5-hydroxytryptamine receptor 1B/0.442
4lsaBLDProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.442
4rpgGDUUDP-galactopyranose mutase5.4.99.90.442
4tnzTTPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.442
1b9iPXG3-amino-5-hydroxybenzoate synthase4.2.1.1440.441
1tysTMPThymidylate synthase/0.441
1xs7MMIBeta-secretase 13.4.23.460.441
2a59LMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.441
2a94AP0L-lactate dehydrogenase1.1.1.270.441
2bdyUNBProthrombin3.4.21.50.441
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.441
2hl2SSAThreonine--tRNA ligase6.1.1.30.441
2nnlNAPDihydroflavonol 4-reductase1.1.1.2190.441
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.441
2ohjFMNType A flavoprotein FprA10.441
2q1wNADPutative nucleotide sugar epimerase/ dehydratase/0.441
2q7hYLYPyrrolysine--tRNA ligase/0.441
2vqbNAPPutative flavin-containing monooxygenase/0.441
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
3fp0FP015-O-acetyltransferase/0.441
3fwgCAMCamphor 5-monooxygenase1.14.15.10.441
3hxcBD6Geranylgeranyl transferase type-2 subunit beta2.5.1.600.441
3mteSAM16S rRNA (adenine(1408)-N(1))-methyltransferase2.1.1.1800.441
3s1dZIRCytokinin dehydrogenase 11.5.99.120.441
4awsFMNNADH:flavin oxidoreductase Sye1/0.441
4earIM5Purine nucleoside phosphorylase2.4.2.10.441
4rphGDUUDP-galactopyranose mutase5.4.99.90.441
4zwpM44Xaa-Pro dipeptidase3.4.13.90.441
5hwoHMGHydroxymethylglutaryl-CoA synthase/0.441
1lvu9PPPurine nucleoside phosphorylase2.4.2.10.440
1me6IVSPlasmepsin-23.4.23.390.440
1q23FUAChloramphenicol acetyltransferase2.3.1.280.440
1tkcM6TTransketolase 12.2.1.10.440
1v5y4HCMajor NAD(P)H-flavin oxidoreductase1.6.990.440
1zemNADXylitol dehydrogenase/0.440
2daaDCSD-alanine aminotransferase2.6.1.210.440
2e0nSAHPrecorrin-2 C20-methyltransferase/0.440
2ejzSAHDiphthine synthase/0.440
2fhlBNIAvidin-related protein 4/5/0.440
2huxSAHDiphthine synthase/0.440
2i65NADADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.440
2ifaFMNUncharacterized protein/0.440
2jf0HBPAcetylcholinesterase3.1.1.70.440
2oapANPType II secretion system protein (GspE-2)/0.440
2pja33ZCarboxypeptidase B/0.440
2pnjCHDFerrochelatase, mitochondrial4.99.1.10.440
2qf2GDPPhosphoenolpyruvate carboxykinase, cytosolic [GTP]4.1.1.320.440
2yyeAPCSelenide, water dikinase2.7.9.30.440
2zs8ADPPantothenate kinase2.7.1.330.440
3af4GCPPantothenate kinase2.7.1.330.440
3dhaC6LN-acyl homoserine lactonase AiiA3.1.1.810.440
3dziRGTADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.440
3gdpFAD(R)-mandelonitrile lyase 24.1.2.100.440
3hdyGDUUDP-galactopyranose mutase/0.440
3lq4TDPPyruvate dehydrogenase E1 component1.2.4.10.440
3zhoFMNNAD(P)H dehydrogenase (quinone)/0.440
3zksWZVBeta-secretase 23.4.23.450.440
4eywL0RCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.440
4f0rMTA5-methylthioadenosine/S-adenosylhomocysteine deaminase/0.440
4gv08MEPoly [ADP-ribose] polymerase 32.4.2.300.440
4j491J1Uncharacterized protein/0.440
4j75TYMTryptophan--tRNA ligase/0.440
5ch7MD1DMSO reductase family type II enzyme, molybdopterin subunit/0.440