sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4xym | COA | Acyl-CoA synthetase (NDP forming) |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4xym | COA | Acyl-CoA synthetase (NDP forming) | / | 1.000 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.634 | |
| 4xz3 | COA | Acyl-CoA synthetase (NDP forming) | / | 0.627 | |
| 4yak | ACO | Acyl-CoA synthetase (NDP forming) | / | 0.559 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.517 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.513 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.512 | |
| 1zdw | FLV | Prenyltransferase | / | 0.509 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.502 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.498 | |
| 3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.498 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.497 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.497 | |
| 3akm | 11D | Fatty acid-binding protein, intestinal | / | 0.497 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.496 | |
| 4gl4 | NAI | Alcohol dehydrogenase class-3 | / | 0.496 | |
| 4ktf | 1TM | Cytochrome P450 | / | 0.496 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.494 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.493 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.493 | |
| 3pd4 | A3G | Threonine--tRNA ligase | 6.1.1.3 | 0.493 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.492 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.491 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.490 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.489 | |
| 2vtd | LKM | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.489 | |
| 3akn | 11D | Fatty acid-binding protein, intestinal | / | 0.489 | |
| 3qeo | LLT | Deoxycytidine kinase | 2.7.1.74 | 0.489 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.488 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.488 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.488 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.488 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.487 | |
| 4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.486 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.485 | |
| 1r2j | FAD | FkbI | / | 0.485 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.485 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.485 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.484 | |
| 3tvq | DQH | Multifunctional cyclase-dehydratase-3-O-methyl transferase TcmN | 2.1.1 | 0.484 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.483 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.483 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.483 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.483 | |
| 2lfo | GCH | Fatty acid-binding protein, liver | / | 0.482 | |
| 4iae | 1DX | Alr2278 protein | / | 0.481 | |
| 2oby | NAP | Quinone oxidoreductase PIG3 | 1 | 0.480 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.480 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.480 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.480 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.480 | |
| 4rri | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.480 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.479 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.479 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.479 | |
| 3nd1 | SAH | Precorrin-6A synthase (Deacetylating) | / | 0.479 | |
| 3r7k | FDA | Probable acyl CoA dehydrogenase | / | 0.479 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.478 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.478 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.477 | |
| 2ejz | SAH | Diphthine synthase | / | 0.477 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.477 | |
| 2vte | IK4 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.477 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.477 | |
| 3iqi | ASN_GLU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.477 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.476 | |
| 1osv | CHC | Bile acid receptor | / | 0.476 | |
| 1xkv | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.476 | |
| 4ktl | 1CQ | Cytochrome P450 | / | 0.476 | |
| 4yao | FMN | NADPH--cytochrome P450 reductase | / | 0.476 | |
| 1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.475 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.475 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.475 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.475 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.475 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.475 | |
| 3nx2 | FER | Ferulic acid decarboxylase | / | 0.475 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.475 | |
| 4v2g | ITC | Tetracycline repressor protein class D | / | 0.475 | |
| 1kqw | RTL | Cellular retinol-binding protein type II | / | 0.474 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.474 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.474 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.474 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.473 | |
| 1foa | UD1 | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | 2.4.1.101 | 0.473 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.473 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.473 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.473 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.473 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.473 | |
| 4ubv | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.473 | |
| 1beu | IPL | Tryptophan synthase alpha chain | / | 0.472 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.472 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.472 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.472 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.472 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.472 | |
| 4g73 | NAI | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.472 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.472 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.471 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.471 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.471 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.471 | |
| 1fx9 | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.470 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.470 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.470 | |
| 3bl7 | DD1 | m7GpppX diphosphatase | 3.6.1.59 | 0.470 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.470 | |
| 4imf | SI3 | N-acetylneuraminate lyase | / | 0.470 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.469 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.469 | |
| 3gob | HXX | DdmC | / | 0.469 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.469 | |
| 4jda | A9S | Abscisic acid receptor PYL3 | / | 0.469 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.469 | |
| 5c1m | CLR | Mu-type opioid receptor | / | 0.469 | |
| 2pb6 | SAH | Diphthine synthase | / | 0.468 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.468 | |
| 3hwx | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.468 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.468 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.468 | |
| 4dja | FAD | (6-4) photolyase | / | 0.468 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.468 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.468 | |
| 4xcv | NDP | Probable hydroxyacid dehydrogenase protein | / | 0.468 | |
| 1dgm | ADN | Adenosine kinase | 2.7.1.20 | 0.467 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.467 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.467 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.467 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.467 | |
| 2xpu | TDC | Tetracycline repressor protein class D | / | 0.467 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.467 | |
| 4xr9 | NAD | CalS8 | / | 0.467 | |
| 5ej6 | TD6 | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.467 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.466 | |
| 1y7l | ASN_LEU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.466 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.466 | |
| 2fto | CB3 | Thymidylate synthase | / | 0.466 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.466 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.466 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.466 | |
| 4rr9 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.466 | |
| 4rww | 2BA | Lmo2692 protein | / | 0.466 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.466 | |
| 1a5b | IGP | Tryptophan synthase alpha chain | / | 0.465 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.465 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.465 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.465 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.465 | |
| 3lnb | COA | N-acetyltransferase family protein | / | 0.465 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.465 | |
| 3vuc | HHE | Renin | 3.4.23.15 | 0.465 | |
| 3zs7 | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.465 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.465 | |
| 4ej1 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.465 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.465 | |
| 4zow | CLM | Multidrug transporter MdfA | / | 0.465 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.464 | |
| 1fxf | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.464 | |
| 1m8g | NAD | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.464 | |
| 1ozh | HE3 | Acetolactate synthase, catabolic | 2.2.1.6 | 0.464 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.464 | |
| 3c15 | FOK | Adenylate cyclase type 2 | / | 0.464 | |
| 3c15 | FOK | Adenylate cyclase type 5 | / | 0.464 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.464 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.464 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.464 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.464 | |
| 4kto | FAD | Putative isovaleryl-CoA dehydrogenase protein | / | 0.464 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.463 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.463 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.463 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.463 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.463 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.463 | |
| 4dpu | AGS | Mevalonate diphosphate decarboxylase | / | 0.463 | |
| 4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 4n4v | 2GY | Tankyrase-1 | 2.4.2.30 | 0.463 | |
| 1cjv | FOK | Adenylate cyclase type 2 | / | 0.462 | |
| 1cjv | FOK | Adenylate cyclase type 5 | / | 0.462 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.462 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.462 | |
| 1wp4 | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.462 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.462 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.462 | |
| 2j5x | GSP | ADP-ribosylation factor 6 | / | 0.462 | |
| 2rir | NAP | Dipicolinate synthase subunit A | / | 0.462 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.462 | |
| 4ap1 | NAP | Steroid monooxygenase | / | 0.462 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.462 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.462 | |
| 1k27 | MTM | S-methyl-5'-thioadenosine phosphorylase | / | 0.461 | |
| 2ab8 | MTP | Adenosine kinase | 2.7.1.20 | 0.461 | |
| 2e15 | SAH | Diphthine synthase | / | 0.461 | |
| 2oc9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.461 | |
| 3ant | S82 | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.461 | |
| 3own | 3OW | Renin | 3.4.23.15 | 0.461 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.461 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.461 | |
| 1f4e | TPR | Thymidylate synthase | / | 0.460 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 1q20 | PLO | Sulfotransferase family cytosolic 2B member 1 | 2.8.2.2 | 0.460 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.460 | |
| 2jcv | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.460 | |
| 2npn | SAM | Putative cobalamin synthesis related protein | / | 0.460 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.460 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.460 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.460 | |
| 3g5h | YTT | Mycocyclosin synthase | 1.14.21.9 | 0.460 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.460 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.460 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.459 | |
| 1kvk | ATP | Mevalonate kinase | 2.7.1.36 | 0.459 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.459 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.459 | |
| 2e4n | SAH | Diphthine synthase | / | 0.459 | |
| 2fvl | NAP | Aldo-keto reductase family 1 member C4 | 1.1.1.225 | 0.459 | |
| 2ou5 | FMN | Pyridoxamine 5'-phosphate oxidase-related FMN-binding protein | / | 0.459 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.459 | |
| 3vsw | R31 | Renin | 3.4.23.15 | 0.459 | |
| 3w1w | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.459 | |
| 3zbr | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.459 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.459 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.459 | |
| 4jic | FMN | GTN Reductase | / | 0.459 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.459 | |
| 5ej4 | TD6 | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.459 | |
| 2fa3 | ACO | Hydroxymethylglutaryl-CoA synthase | / | 0.458 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.458 | |
| 3csd | EMO | Putative ketoacyl reductase | 1.3.1 | 0.458 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 3f63 | GTX | Glutathione transferase GST1-4 | / | 0.458 | |
| 3own | 3OX | Renin | 3.4.23.15 | 0.458 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.458 | |
| 4iah | 1DX | Alr2278 protein | / | 0.458 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.457 | |
| 1fwm | CB3 | Thymidylate synthase | / | 0.457 | |
| 1gpd | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.457 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.457 | |
| 2jcx | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.457 | |
| 2owg | SAH | Diphthine synthase | / | 0.457 | |
| 3ad9 | NAD | Subunit alpha of sarocosine oxidase | / | 0.457 | |
| 3h06 | VBP | Glutamate receptor 2 | / | 0.457 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 3maa | FKP | Adenylate cyclase type 2 | / | 0.457 | |
| 3maa | FKP | Adenylate cyclase type 5 | / | 0.457 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 3zht | TD9 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.457 | |
| 4i13 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.457 | |
| 1mrq | STR | Aldo-keto reductase family 1 member C1 | / | 0.456 | |
| 1o97 | FAD | Electron transfer flavoprotein subunit alpha | / | 0.456 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.456 | |
| 1wxj | IPL | Tryptophan synthase alpha chain | / | 0.456 | |
| 2dsg | SAH | Diphthine synthase | / | 0.456 | |
| 2huv | SAH | Diphthine synthase | / | 0.456 | |
| 2qw0 | 34Z | 4-chlorobenzoyl CoA ligase | / | 0.456 | |
| 2v58 | LZJ | Biotin carboxylase | 6.3.4.14 | 0.456 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.456 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.456 | |
| 3oag | LPQ | Renin | 3.4.23.15 | 0.456 | |
| 4aos | NAP | Steroid monooxygenase | / | 0.456 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.456 | |
| 4ol0 | GTP | GTP-binding nuclear protein Ran | / | 0.456 | |
| 5a9s | NAP | Putative dehydrogenase | / | 0.456 | |
| 5cvh | ADP | Casein kinase II subunit alpha | 2.7.11.1 | 0.456 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.455 | |
| 1ee9 | NAD | Methylenetetrahydrofolate dehydrogenase [NAD(+)] | 1.5.1.15 | 0.455 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.455 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.455 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.455 | |
| 2f6r | ACO | Bifunctional coenzyme A synthase | / | 0.455 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.455 | |
| 2p9d | SAH | Diphthine synthase | / | 0.455 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 2wya | HMG | Hydroxymethylglutaryl-CoA synthase, mitochondrial | 2.3.3.10 | 0.455 | |
| 2yei | XQI | Heat shock protein HSP 90-alpha | / | 0.455 | |
| 2zyn | BCD | Periplasmic binding protein | / | 0.455 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.455 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.455 | |
| 3zcs | CAW | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.455 | |
| 4g2g | TDH | Mycocyclosin synthase | 1.14.21.9 | 0.455 | |
| 4kln | AGS | Transitional endoplasmic reticulum ATPase | 3.6.4.6 | 0.455 | |
| 4qai | FMN | NADPH dehydrogenase | / | 0.455 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.455 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.455 | |
| 1a4i | NDP | C-1-tetrahydrofolate synthase, cytoplasmic | 1.5.1.5 | 0.454 | |
| 1cjk | FOK | Adenylate cyclase type 2 | / | 0.454 | |
| 1cjk | FOK | Adenylate cyclase type 5 | / | 0.454 | |
| 1l2t | ATP | Uncharacterized ABC transporter ATP-binding protein MJ0796 | / | 0.454 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.454 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.454 | |
| 1ow3 | GDP | Transforming protein RhoA | / | 0.454 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 2a1o | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.454 | |
| 2pca | SAH | Diphthine synthase | / | 0.454 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.454 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.454 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.454 | |
| 2y3r | TRK | TamL | / | 0.454 | |
| 2z6r | SAH | Diphthine synthase | / | 0.454 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.454 | |
| 3oix | FMN | Dihydroorotate dehydrogenase | / | 0.454 | |
| 4a6r | TA8 | Probable aminotransferase | / | 0.454 | |
| 4e0u | 0MV | Cyclic dipeptide N-prenyltransferase | / | 0.454 | |
| 4oqy | NDP | (S)-imine reductase | / | 0.454 | |
| 4r81 | FMN | Predicted NADH dehydrogenase | / | 0.454 | |
| 5eja | TD6 | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.454 | |
| 1f5f | DHT | Sex hormone-binding globulin | / | 0.453 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 1jip | KTN | 6-deoxyerythronolide B hydroxylase | / | 0.453 | |
| 1m8k | NAD | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.453 | |
| 1sd1 | FMC | S-methyl-5'-thioadenosine phosphorylase | / | 0.453 | |
| 2hl0 | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.453 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.453 | |
| 2v59 | LZK | Biotin carboxylase | 6.3.4.14 | 0.453 | |
| 2vn1 | FK5 | Peptidylprolyl isomerase | / | 0.453 | |
| 2xs0 | ANP | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.453 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 3ndc | SAH | Precorrin-4 C(11)-methyltransferase | 2.1.1.133 | 0.453 | |
| 3zhu | TD8 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.453 | |
| 3zxs | FAD | Deoxyribodipyrimidine photolyase-related protein | / | 0.453 | |
| 4bmp | FMN | Protein NrdI | / | 0.453 | |
| 4e5p | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.453 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.453 | |
| 4ilx | 1EZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.453 | |
| 4rr6 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.453 | |
| 4rrm | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.453 | |
| 4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.453 | |
| 5gcn | COA | HAT A1 | / | 0.453 | |
| 4zj8 | SUV | Orexin receptor type 1 | / | 0.453 | |
| 1eio | GCH | Gastrotropin | / | 0.452 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.452 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.452 | |
| 1lf2 | R37 | Plasmepsin-2 | 3.4.23.39 | 0.452 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.452 | |
| 2abj | CBC | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.452 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.452 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.452 | |
| 2ic5 | GDP | Ras-related C3 botulinum toxin substrate 3 | / | 0.452 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 3bxx | QUE | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.452 | |
| 3ha5 | SFG | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.452 | |
| 3qyk | IE2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.452 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.452 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.452 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.452 | |
| 4e2b | FMN | Dehydrogenase | / | 0.452 | |
| 4hxy | NDP | Plm1 | / | 0.452 | |
| 4i6a | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.452 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.452 | |
| 4y9q | C2E | Uncharacterized protein | / | 0.452 | |
| 5bp9 | SAH | Putative methyltransferase protein | / | 0.452 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.452 | |
| 1a9z | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.451 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.451 | |
| 1o6r | R19 | Squalene--hopene cyclase | 4.2.1.129 | 0.451 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.451 | |
| 1rsg | FAD | Polyamine oxidase FMS1 | / | 0.451 | |
| 1tl7 | FOK | Adenylate cyclase type 2 | / | 0.451 | |
| 1tl7 | FOK | Adenylate cyclase type 5 | / | 0.451 | |
| 1ywg | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.451 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.451 | |
| 2bxm | IMN | Serum albumin | / | 0.451 | |
| 2j83 | BAT | Ulilysin | 3.4.24 | 0.451 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 3da2 | 4MD | Carbonic anhydrase 13 | 4.2.1.1 | 0.451 | |
| 3eld | SFG | Methyltransferase | / | 0.451 | |
| 3eon | 341 | Glutaryl-CoA dehydrogenase | / | 0.451 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.451 | |
| 3h4v | DVP | Pteridine reductase 1 | 1.5.1.33 | 0.451 | |
| 3ioc | A5D | Pantothenate synthetase | 6.3.2.1 | 0.451 | |
| 3s3v | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 3ute | FAD | UDP-galactopyranose mutase | / | 0.451 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.451 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.451 | |
| 4mt9 | 2D6 | Tankyrase-1 | 2.4.2.30 | 0.451 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.451 | |
| 4x7w | MVI | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.451 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.451 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.450 | |
| 1gpe | FAD | Glucose oxidase | 1.1.3.4 | 0.450 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.450 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.450 | |
| 2fhj | H4Z | Formylmethanofuran--tetrahydromethanopterin formyltransferase | 2.3.1.101 | 0.450 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 2p33 | J07 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.450 | |
| 2rkv | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.450 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.450 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.450 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.450 | |
| 3ig6 | 438 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.450 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 3ljt | LA3 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.450 | |
| 3t1t | GDP | Probable gliding protein mglA | / | 0.450 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.450 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.450 | |
| 4azw | ATP | O-antigen chain terminator bifunctional methyltransferase/kinase WbdD | / | 0.450 | |
| 4dbc | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.450 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.450 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.450 | |
| 4mv1 | ADP | Biotin carboxylase | 6.3.4.14 | 0.450 | |
| 4r1l | ADP | Phenylacetate-coenzyme A ligase | / | 0.450 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 1p44 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.449 | |
| 1tka | N3T | Transketolase 1 | 2.2.1.1 | 0.449 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.449 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.449 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.449 | |
| 2jfh | LK1 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.449 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.449 | |
| 3d9z | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.449 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.449 | |
| 3jqp | A2P | Ferredoxin--NADP reductase, apicoplast | / | 0.449 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.449 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.449 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.449 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.449 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.449 | |
| 3v1s | 0LH | Strictosidine synthase | 4.3.3.2 | 0.449 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.449 | |
| 4eji | 0QA | Cytochrome P450 2A13 | 1.14.14.1 | 0.449 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.449 | |
| 4h0x | NAD | Iota toxin component Ia | / | 0.449 | |
| 4ubt | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.449 | |
| 5jsc | FAD | Putative acyl-CoA dehydrogenase | / | 0.449 | |
| 1b5e | DCM | Deoxycytidylate 5-hydroxymethyltransferase | 2.1.2.8 | 0.448 | |
| 1m9m | 6NI | Nitric oxide synthase, endothelial | 1.14.13.39 | 0.448 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.448 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.448 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 1zio | AP5 | Adenylate kinase | / | 0.448 | |
| 2bxq | IMN | Serum albumin | / | 0.448 | |
| 2huq | SAH | Diphthine synthase | / | 0.448 | |
| 2iya | ZIO | Oleandomycin glycosyltransferase | / | 0.448 | |
| 2jfg | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.448 | |
| 2uxp | CLM | HTH-type transcriptional regulator TtgR | / | 0.448 | |
| 2xvf | FAD | Putative flavin-containing monooxygenase | / | 0.448 | |
| 2z4s | ADP | Chromosomal replication initiator protein DnaA | / | 0.448 | |
| 2zcv | NDP | Quinone oxidoreductase 2 | 1.6.5.2 | 0.448 | |
| 3bgx | TMP | Thymidylate synthase | / | 0.448 | |
| 3c14 | FOK | Adenylate cyclase type 2 | / | 0.448 | |
| 3c14 | FOK | Adenylate cyclase type 5 | / | 0.448 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.448 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.448 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 4dsh | FDA | Uncharacterized protein | / | 0.448 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 4g47 | TZF | Mycocyclosin synthase | 1.14.21.9 | 0.448 | |
| 4jnc | 1LF | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.448 | |
| 4x28 | FDA | Acyl-CoA dehydrogenase FadE26 | / | 0.448 | |
| 4x28 | FDA | Acyl-CoA dehydrogenase FadE27 | / | 0.448 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.448 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.447 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 1egd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.447 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.447 | |
| 2ek2 | SAH | Diphthine synthase | / | 0.447 | |
| 2ekl | NAD | D-3-phosphoglycerate dehydrogenase | / | 0.447 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.447 | |
| 3ed1 | GA3 | Gibberellin receptor GID1 | / | 0.447 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.447 | |
| 3uk6 | ADP | RuvB-like 2 | 3.6.4.12 | 0.447 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.447 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.447 | |
| 4f65 | 0S9 | Fibroblast growth factor receptor 1 | / | 0.447 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.447 | |
| 4gyz | D5M | Tyrosyl-DNA phosphodiesterase 2 | 3.1.4 | 0.447 | |
| 4lva | 20M | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.447 | |
| 4x7z | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.447 | |
| 4yp7 | NAP | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.447 | |
| 1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.446 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 1h74 | ADP | Homoserine kinase | 2.7.1.39 | 0.446 | |
| 1kfb | IGP | Tryptophan synthase alpha chain | / | 0.446 | |
| 1mp0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.446 | |
| 1u0h | FOK | Adenylate cyclase type 2 | / | 0.446 | |
| 1u0h | FOK | Adenylate cyclase type 5 | / | 0.446 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.446 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.446 | |
| 2zjw | REF | Casein kinase II subunit alpha | 2.7.11.1 | 0.446 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 3kb1 | ADP | Iron-sulfur cluster carrier protein | / | 0.446 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.446 | |
| 3pe2 | E1B | Casein kinase II subunit alpha | 2.7.11.1 | 0.446 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.446 | |
| 4ii4 | BYC | 1,2-phenylacetyl-CoA epoxidase, subunit A | 1.14.13.149 | 0.446 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.446 | |
| 4ly9 | 1YY | Glucokinase regulatory protein | / | 0.446 | |
| 4v12 | POG | MaoC like domain protein | / | 0.446 | |
| 5esd | TDP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.446 | |
| 1cju | FOK | Adenylate cyclase type 2 | / | 0.445 | |
| 1cju | FOK | Adenylate cyclase type 5 | / | 0.445 | |
| 1f28 | UMP | Thymidylate synthase | 2.1.1.45 | 0.445 | |
| 1fdw | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.445 | |
| 1gs4 | ZK5 | Androgen receptor | / | 0.445 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.445 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 2d8a | NAD | L-threonine 3-dehydrogenase | / | 0.445 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.445 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.445 | |
| 2onm | ADP | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.445 | |
| 3dt2 | GTP | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | 4.1.1.32 | 0.445 | |
| 3dv3 | MEK | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.445 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.445 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.445 | |
| 3rua | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.445 | |
| 3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.445 | |
| 3zvm | ADP | Bifunctional polynucleotide phosphatase/kinase | 2.7.1.78 | 0.445 | |
| 4a2z | VIQ | Glycylpeptide N-tetradecanoyltransferase | / | 0.445 | |
| 4en4 | ATP | Pyridoxal kinase | 2.7.1.35 | 0.445 | |
| 4g6h | NAI | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.445 | |
| 5flt | VJJ | Carbonic anhydrase 2 | 4.2.1.1 | 0.445 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.445 | |
| 1b5d | DCM | Deoxycytidylate 5-hydroxymethyltransferase | 2.1.2.8 | 0.444 | |
| 1bnt | AL2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.444 | |
| 1dv2 | ATP | Biotin carboxylase | 6.3.4.14 | 0.444 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.444 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 1l8q | ADP | Chromosomal replication initiator protein DnaA | / | 0.444 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 1r8b | ATP | CCA-adding enzyme | 2.7.7.72 | 0.444 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.444 | |
| 1upc | TPP | N(2)-(2-carboxyethyl)arginine synthase | / | 0.444 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 2fb2 | SAM | GTP 3',8-cyclase | 4.1.99.18 | 0.444 | |
| 2i7p | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.444 | |
| 2ij7 | TPF | Mycocyclosin synthase | 1.14.21.9 | 0.444 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.444 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2wed | PP6 | Penicillopepsin-1 | 3.4.23.20 | 0.444 | |
| 3c1t | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.444 | |
| 3cgf | JNF | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.444 | |
| 3igp | DT7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.444 | |
| 3lfm | 3DT | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.444 | |
| 3p8z | 36A | Genome polyprotein | 2.1.1.56 | 0.444 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.444 | |
| 4bgi | I4I | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 4boe | CLR | Japanin | / | 0.444 | |
| 4bqh | 9VU | UDP-N-acetylglucosamine pyrophosphorylase, putative | / | 0.444 | |
| 4cax | 646 | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.444 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.444 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.444 | |
| 5hsa | FAS | Alcohol oxidase 1 | 1.1.3.13 | 0.444 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.443 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.443 | |
| 1ra2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1ve3 | SAM | Uncharacterized protein | / | 0.443 | |
| 1xq0 | 4TR | Carbonic anhydrase 2 | 4.2.1.1 | 0.443 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.443 | |
| 1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.443 | |
| 2bxo | OPB | Serum albumin | / | 0.443 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 2cvu | CDP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.443 | |
| 2cvz | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.443 | |
| 2el3 | SAH | Diphthine synthase | / | 0.443 | |
| 2fxf | ACO | Diamine acetyltransferase 1 | / | 0.443 | |
| 2p1t | 3TN | Retinoic acid receptor RXR-alpha | / | 0.443 | |
| 2web | PP4 | Penicillopepsin-1 | 3.4.23.20 | 0.443 | |
| 2yxu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.443 | |
| 3t3q | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.443 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 4ejv | LCL | Transcriptional regulator TcaR | / | 0.443 | |
| 4h6p | FMN | Chromate reductase | / | 0.443 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.443 | |
| 4zgs | NAD | Putative D-lactate dehydrogenase | / | 0.443 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.442 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 1h35 | R01 | Squalene--hopene cyclase | 4.2.1.129 | 0.442 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
| 1tdu | DUR | Thymidylate synthase | / | 0.442 | |
| 2a1m | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.442 | |
| 2brb | PFQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.442 | |
| 2fon | FAD | Acyl-coenzyme A oxidase | / | 0.442 | |
| 2hr8 | SAH | Diphthine synthase | / | 0.442 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.442 | |
| 2nni | MTK | Cytochrome P450 2C8 | / | 0.442 | |
| 2w6o | OA3 | Biotin carboxylase | 6.3.4.14 | 0.442 | |
| 3aw9 | GDU | NAD-dependent epimerase/dehydratase | / | 0.442 | |
| 3b1d | PLS | BetaC-S lyase | / | 0.442 | |
| 3e8x | NAP | BH1520 protein | / | 0.442 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.442 | |
| 3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.442 | |
| 3qj0 | QI3 | Botulinum neurotoxin type A | 3.4.24.69 | 0.442 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.442 | |
| 3to3 | ATP | Petrobactin biosynthesis protein AsbB | / | 0.442 | |
| 4a31 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.442 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.442 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.442 | |
| 4b1r | ITC | Tetracycline repressor protein class D | / | 0.442 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.442 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.442 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.442 | |
| 4mv4 | ACP | Biotin carboxylase | 6.3.4.14 | 0.442 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.442 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.442 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.442 | |
| 4qzu | RTL | Retinol-binding protein 2 | / | 0.442 | |
| 4rrc | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.442 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.441 | |
| 1jmh | UMP | Thymidylate synthase | / | 0.441 | |
| 1mbt | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.441 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 1y6o | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.441 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.441 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 2bpo | FAD | NADPH--cytochrome P450 reductase | / | 0.441 | |
| 2dft | ADP | Shikimate kinase | 2.7.1.71 | 0.441 | |
| 2emr | SAH | Diphthine synthase | / | 0.441 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.441 | |
| 3b2s | B2S | Trichothecene 3-O-acetyltransferase | / | 0.441 | |
| 3dhc | CYK | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.441 | |
| 3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.441 | |
| 3gpc | COA | Acyl-coenzyme A synthetase ACSM2A, mitochondrial | 6.2.1.2 | 0.441 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.441 | |
| 3o56 | ZG1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.441 | |
| 3sqw | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.441 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.441 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.441 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 4ele | 31I | Dihydrofolate reductase | / | 0.441 | |
| 4ey2 | 0RM | Metallo-beta-lactamase type 2 | / | 0.441 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.441 | |
| 4jbs | P52 | Endoplasmic reticulum aminopeptidase 2 | 3.4.11 | 0.441 | |
| 4nr4 | 2LK | CREB-binding protein | / | 0.441 | |
| 4u03 | GTP | Cyclic GMP-AMP synthase | / | 0.441 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.441 | |
| 1g41 | ADP | ATP-dependent protease ATPase subunit HslU | / | 0.440 | |
| 1h65 | GDP | Translocase of chloroplast 34 | 3.6.5 | 0.440 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.440 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.440 | |
| 1rx0 | FAD | Isobutyryl-CoA dehydrogenase, mitochondrial | 1.3.99 | 0.440 | |
| 1tou | B1V | Fatty acid-binding protein, adipocyte | / | 0.440 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1vjt | NAD | Alpha-glucosidase, putative | / | 0.440 | |
| 2bei | ACO | Diamine acetyltransferase 2 | 2.3.1.57 | 0.440 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.440 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.440 | |
| 2nnq | T4B | Fatty acid-binding protein, adipocyte | / | 0.440 | |
| 2qn3 | F55 | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.440 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.440 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 2y4g | TIR | TamL | / | 0.440 | |
| 2z4j | DHT | Androgen receptor | / | 0.440 | |
| 3a1c | ACP | Probable copper-exporting P-type ATPase A | 3.6.3.54 | 0.440 | |
| 3b9l | AZZ | Serum albumin | / | 0.440 | |
| 3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.440 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.440 | |
| 3qge | 26F | Genome polyprotein | 2.7.7.48 | 0.440 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.440 | |
| 4dvi | 2IW | Tankyrase-1 | 2.4.2.30 | 0.440 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.440 | |
| 4ejn | 0R4 | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.440 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 4ixd | 1HV | Integrin alpha-L | / | 0.440 | |
| 4mkh | AP5 | Adenylate kinase | / | 0.440 | |
| 4mlp | 2CX | Cryptochrome-2 | / | 0.440 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.440 | |
| 4o67 | 1SY | Cyclic GMP-AMP synthase | / | 0.440 | |
| 4rvn | COA | Phenylacetate-coenzyme A ligase | / | 0.440 | |
| 4yp6 | NAP | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.440 | |
| 4z4p | SAH | Histone-lysine N-methyltransferase 2D | 2.1.1.43 | 0.440 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.440 | |
| 5eso | TDP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.440 |