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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4x9mFADUncharacterized protein MG039 homolog

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
4x9mFADUncharacterized protein MG039 homolog/1.000
3cukFADD-amino-acid oxidase1.4.3.30.515
3dmeFADPutative conserved exported protein/0.514
2qo9ANPEphrin type-A receptor 32.7.10.10.512
1kifFADD-amino-acid oxidase1.4.3.30.509
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.503
4ocpADPN-acetylhexosamine 1-kinase2.7.1.1620.503
2igoFADPyranose 2-oxidase/0.502
3q3cNADNAD-dependent L-serine dehydrogenase/0.497
4pl0ANPMicrocin-J25 export ATP-binding/permease protein McjD/0.497
1e3eNAIAlcohol dehydrogenase 41.1.1.10.490
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.489
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.489
4mihFADPyranose 2-oxidase1.1.3.100.489
4zohFADPutative oxidoreductase FAD-binding subunit/0.489
1jpaANPEphrin type-B receptor 22.7.10.10.488
1jueFMNDihydroorotate dehydrogenase A (fumarate)1.3.98.10.488
2rghFADAlpha-Glycerophosphate Oxidase/0.485
2zjmF1MBeta-secretase 13.4.23.460.485
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.485
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.484
1l7eNAINAD(P) transhydrogenase subunit alpha part 11.6.1.20.484
3q43D66M1 family aminopeptidase3.4.110.484
1vyrFMNPentaerythritol tetranitrate reductase/0.483
4l03NAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.483
2fgjATPAlpha-hemolysin translocation ATP-binding protein HlyB/0.482
3o03NAPDehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase)/0.482
3h06VBPGlutamate receptor 2/0.480
4xfjANPArgininosuccinate synthase/0.480
4yr9NADL-threonine 3-dehydrogenase, mitochondrial1.1.1.1030.480
1bsvNDPGDP-L-fucose synthase/0.478
2ignFADPyranose 2-oxidase/0.478
3c1y2BADNA integrity scanning protein DisA/0.478
3etdNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.478
3etgNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.478
4gk2L66Ephrin type-A receptor 32.7.10.10.478
4kxn6K62'-deoxynucleoside 5'-phosphate N-hydrolase 1/0.478
1gqtACPRibokinase/0.477
3atzFMNProstaglandin F2a synthase/0.477
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.476
3a292T0Fructose-1,6-bisphosphatase 13.1.3.110.476
3uqdATPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.476
3a1nNADNDP-sugar epimerase/0.475
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.475
1cjkFOKAdenylate cyclase type 2/0.474
1cjkFOKAdenylate cyclase type 5/0.474
2oorNADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.474
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.472
1tqf32PBeta-secretase 13.4.23.460.472
2c54NADGDP-mannose 3,5-epimerase5.1.3.180.472
2qo7ANPEphrin type-A receptor 32.7.10.10.472
2x0iNAIMalate dehydrogenase/0.472
4dn5AGSMitogen-activated protein kinase kinase kinase 142.7.11.250.472
4qecNAPElxO/0.472
1lf2R37Plasmepsin-23.4.23.390.471
4ef8FMNDihydroorotate dehydrogenase (fumarate)/0.471
1icuFMNOxygen-insensitive NAD(P)H nitroreductase/0.470
4eakATP5'-AMP-activated protein kinase subunit gamma-1/0.470
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.470
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.469
3sufSUEPolyprotein/0.469
4gk3L87Ephrin type-A receptor 32.7.10.10.469
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.469
2x0rNADMalate dehydrogenase/0.468
2xrlDXTTetracycline repressor protein class D/0.468
2yyuC5POrotidine 5'-phosphate decarboxylase/0.468
5eccNAPDehydrofolate reductase type I/0.468
1bwsNDPGDP-L-fucose synthase/0.467
1ng4FADGlycine oxidase1.4.3.190.467
1u2gAPRNAD(P) transhydrogenase subunit alpha part 11.6.1.20.467
3oibFDAPutative acyl-CoA dehydrogenase/0.467
4gddNAIUDP-galactopyranose mutase/0.467
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.466
1gheACOAcetyltransferase2.3.10.466
1nuqNXXNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.466
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.466
3nugNADPyridoxal 4-dehydrogenase1.1.1.1070.466
3ruhNADUDP-N-acetylglucosamine 4-epimerase/0.466
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.466
4l7f1V5Mitogen-activated protein kinase 82.7.11.240.466
1drhNAPDihydrofolate reductase1.5.1.30.465
1i3mUD1UDP-glucose 4-epimerase/0.465
2d8aNADL-threonine 3-dehydrogenase/0.465
2xpwOTCTetracycline repressor protein class D/0.465
4n9iPCGCatabolite expression activator/0.465
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.464
2gcgNDPGlyoxylate reductase/hydroxypyruvate reductase1.1.1.790.464
2gtnLIEMitogen-activated protein kinase 14/0.464
3atyFMNProstaglandin F2a synthase/0.464
3f1kNAPUncharacterized oxidoreductase YciK10.464
3inmNDPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.464
3isjA8DPantothenate synthetase6.3.2.10.464
1kc1NDPdTDP-4-dehydrorhamnose reductase1.1.1.1330.463
2a0wDIHPurine nucleoside phosphorylase2.4.2.10.463
2nliFMNLactate oxidase/0.463
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.463
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.463
3p62FMNPentaerythritol tetranitrate reductase/0.463
4ji91M3Tyrosine-protein kinase JAK2/0.463
1i24UPGUDP-sulfoquinovose synthase, chloroplastic3.13.1.10.462
1rneC60Renin3.4.23.150.462
2ggsNDPdTDP-4-dehydrorhamnose reductase/0.462
2ywwATPAspartate carbamoyltransferase regulatory chain/0.462
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.462
3muoZPRProlyl endopeptidase/0.462
4idtT28Mitogen-activated protein kinase kinase kinase 142.7.11.250.462
4o9kCMKArabinose 5-phosphate isomerase/0.462
2xb5I7TTetracycline repressor protein class D/0.461
3copADPGlycogen synthase2.4.1.210.461
3sdkP3NProteasome subunit beta type-53.4.25.10.461
3sdkP3NProteasome subunit beta type-63.4.25.10.461
4fhj0TZPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
4g2fC07Ephrin type-A receptor 32.7.10.10.461
4gyy12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.461
5jscFADPutative acyl-CoA dehydrogenase/0.461
1fwkADPHomoserine kinase2.7.1.390.460
1h50FMNPentaerythritol tetranitrate reductase/0.460
1i59ANPChemotaxis protein CheA2.7.13.30.460
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.460
1n2bPAFPantothenate synthetase6.3.2.10.460
2bunFADAppA protein/0.460
2q5g1FAPeroxisome proliferator-activated receptor delta/0.460
2ql6ADPNicotinamide riboside kinase 1/0.460
2xfsJ01Uncharacterized protein/0.460
3oqkS52Renin3.4.23.150.460
3otwCOAPhosphopantetheine adenylyltransferase/0.460
3tjzGNPADP-ribosylation factor 1/0.460
3wb2YGPUncharacterized protein MJ0488/0.460
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.459
2fy4COACholine O-acetyltransferase2.3.1.60.459
2g8yNADHydroxycarboxylate dehydrogenase B/0.459
2o12FMNChorismate synthase/0.459
3ivgFG5Pantothenate synthetase6.3.2.10.459
3oev3OEProteasome subunit beta type-53.4.25.10.459
3oev3OEProteasome subunit beta type-63.4.25.10.459
3rn8RN8Glutamate receptor 2/0.459
3ruaNADUDP-N-acetylglucosamine 4-epimerase/0.459
4b3aTACTetracycline repressor protein class D/0.459
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.459
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.459
1dr2TAPDihydrofolate reductase1.5.1.30.458
1h63FMNPentaerythritol tetranitrate reductase/0.458
1hncGDNGlutathione S-transferase Mu 22.5.1.180.458
1ryiFADGlycine oxidase1.4.3.190.458
2du8FADD-amino-acid oxidase1.4.3.30.458
2j5xGSPADP-ribosylation factor 6/0.458
2y6o1N1Ephrin type-A receptor 42.7.10.10.458
3af4GCPPantothenate kinase2.7.1.330.458
3d3wNAPL-xylulose reductase1.1.1.100.458
3ddw055Glycogen phosphorylase, liver form2.4.1.10.458
3hx4ANPCalmodulin-domain protein kinase 1/0.458
3ibqATPPyridoxal kinase/0.458
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.458
3sdi3SDProteasome subunit beta type-53.4.25.10.458
3sdi3SDProteasome subunit beta type-63.4.25.10.458
4cax646Glycylpeptide N-tetradecanoyltransferase2.3.1.970.458
4ryvZEAProtein LlR18A/0.458
1jipKTN6-deoxyerythronolide B hydroxylase/0.457
1q12ATPMaltose/maltodextrin import ATP-binding protein MalK/0.457
3b70NAPEnoyl reductase LovC10.457
3nbvANPKetohexokinase/0.457
3uoyFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.457
3uwqU5POrotidine 5'-phosphate decarboxylase/0.457
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.457
5hwsNAP2-dehydropantoate 2-reductase/0.457
1bim0QBRenin3.4.23.150.456
1fxsNAPGDP-L-fucose synthase/0.456
1jedADPSulfate adenylyltransferase/0.456
1lm1FMNFerredoxin-dependent glutamate synthase 21.4.7.10.456
1rj6AZMCarbonic anhydrase 144.2.1.10.456
2hu2NADC-terminal binding protein 1/0.456
2x0eTYDWsaF/0.456
3il1B5DGlutamate receptor 2/0.456
3kb6NADD-lactate dehydrogenase/0.456
3q44D50M1 family aminopeptidase3.4.110.456
3upkUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.456
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.456
4dieC5PCytidylate kinase/0.456
4m9aFDAAcyl-CoA dehydrogenase/0.456
1lbcCYZGlutamate receptor 2/0.455
2ggqTTPDual sugar-1-phosphate nucleotidylyltransferase/0.455
2x7hPFNProstaglandin reductase 310.455
3bw2FMNPutative 2-nitropropane dioxygenase/0.455
3ig6438Urokinase-type plasminogen activator3.4.21.730.455
3k4cFADPyranose 2-oxidase/0.455
3oriAGSSerine/threonine protein kinase/0.455
3own3OWRenin3.4.23.150.455
3p82FMNPentaerythritol tetranitrate reductase/0.455
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.455
1naiNADUDP-glucose 4-epimerase5.1.3.20.454
1nuuNADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.454
1yb5NAPQuinone oxidoreductase1.6.5.50.454
2bbwGP5Adenylate kinase 4, mitochondrial/0.454
2gjlFMNNitronate monooxygenase1.13.12.160.454
2lbaCHOFatty acid binding protein 6/0.454
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.454
3allFAD2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase/0.454
3s1dZIRCytokinin dehydrogenase 11.5.99.120.454
3sf6FDAGlutaryl-CoA dehydrogenase/0.454
3x2vATPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.454
3zuxTCHTransporter/0.454
4a99FADTetX family tetracycline inactivation enzyme/0.454
4ajp88NL-lactate dehydrogenase A chain1.1.1.270.454
4b5nFMNNAD(P)H:flavin oxidoreductase Sye4/0.454
4i6aHMG3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.454
4m5pFMNNADPH dehydrogenase/0.454
5c8wPCGcGMP-dependent protein kinase 22.7.11.120.454
5dp2NAPCurF/0.454
1f8gNADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.453
1nboNADGlyceraldehyde-3-phosphate dehydrogenase A, chloroplastic1.2.1.130.453
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.453
2is0I03Beta-secretase 13.4.23.460.453
2qfvNAPIsocitrate dehydrogenase [NADP], mitochondrial1.1.1.420.453
2rioADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.453
2w9hTOPDihydrofolate reductase1.5.1.30.453
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.453
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.453
3rucNADUDP-N-acetylglucosamine 4-epimerase/0.453
3wagTYDGlycosyltransferase/0.453
4gllNADUDP-glucuronic acid decarboxylase 14.1.1.350.453
4h8aNAIUreidoglycolate dehydrogenase (NAD(+))1.1.1.3500.453
4lcjNADC-terminal-binding protein 2/0.453
4n9wGDPPhosphatidyl-myo-inositol mannosyltransferase2.4.1.570.453
4tmcFMNOld yellow enzyme/0.453
5js6NAD17-beta-hydroxysteroid dehydrogenase 141.1.10.453
1gzuNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.452
1h6cNDPGlucose--fructose oxidoreductase1.1.99.280.452
1hwzNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.452
1ia1NDPDihydrofolate reductase1.5.1.30.452
1oyaFMNNADPH dehydrogenase 11.6.99.10.452
1u7tNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.452
1wntNAPL-xylulose reductase1.1.1.100.452
2henADPEphrin type-B receptor 22.7.10.10.452
2ituITQEpidermal growth factor receptor2.7.10.10.452
2pamTYDTDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase5.3.2.30.452
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.452
2vkvTDCTetracycline repressor protein class D/0.452
3ak4NADNADH-dependent quinuclidinone reductase/0.452
3hyoADPPyridoxal kinase/0.452
3pe6ZYHMonoglyceride lipase/0.452
4frkDWDBeta-secretase 13.4.23.460.452
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.452
5fklTDCTetracycline repressor protein class D/0.452
1llqNADNAD-dependent malic enzyme, mitochondrial1.1.1.380.451
1p4aPCPPur operon repressor/0.451
1q8yADPSerine/threonine-protein kinase SKY12.7.11.10.451
1towCRZFatty acid-binding protein, adipocyte/0.451
2b7aIZATyrosine-protein kinase JAK2/0.451
2o7oDXTTetracycline repressor protein class D/0.451
3bk2U5PRibonuclease J/0.451
3c212BADNA integrity scanning protein DisA/0.451
3ik6HCZGlutamate receptor 2/0.451
3lsiFADPyranose 2-oxidase/0.451
4jq9FADDihydrolipoyl dehydrogenase/0.451
1bw9NADPhenylalanine dehydrogenase/0.450
1h74ADPHomoserine kinase2.7.1.390.450
1lrjUD1UDP-glucose 4-epimerase5.1.3.20.450
1m78NDPDihydrofolate reductase1.5.1.30.450
1t0lNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.450
1vyw292Cyclin-dependent kinase 22.7.11.220.450
2fxv5GPXanthine phosphoribosyltransferase2.4.2.220.450
2i4qUA4Renin3.4.23.150.450
2p5uNADUDP-glucose 4-epimerase/0.450
2vkeTACTetracycline repressor protein class D/0.450
2vx07X7Ephrin type-B receptor 42.7.10.10.450
3a4vNADNDP-sugar epimerase/0.450
3bhtMFRCyclin-dependent kinase 22.7.11.220.450
3cxw7CPSerine/threonine-protein kinase pim-12.7.11.10.450
3gy0NAPNAD(P)-dependent oxidoreductase/0.450
3ogxH1SPeptidoglycan recognition protein 1/0.450
3p74FMNPentaerythritol tetranitrate reductase/0.450
3rufNADUDP-N-acetylglucosamine 4-epimerase/0.450
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.450
3wdsNADNADH-dependent quinuclidinone reductase/0.450
4hiaFMNLOV protein/0.450
4hmsFMNPhenazine biosynthesis protein PhzG1.40.450
4jb1FADUDP-N-acetylenolpyruvoylglucosamine reductase/0.450
4z24FADPutative GMC-type oxidoreductase R13510.450
5a3cNADSIR2 family protein/0.450
4xnw2IDP2Y purinoceptor 1/0.450
1kqcFMNOxygen-insensitive NAD(P)H nitroreductase/0.449
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.449
2c29NAPDihydroflavonol 4-reductase/0.449
2g5cNADPrephenate dehydrogenase/0.449
2qfxNDPIsocitrate dehydrogenase [NADP], mitochondrial1.1.1.420.449
2w06FRVCyclin-dependent kinase 22.7.11.220.449
3b6zCO7Enoyl reductase LovC10.449
3hgoFMN12-oxophytodienoate reductase 31.3.1.420.449
3in6FMNUncharacterized protein/0.449
3mddFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.449
3owj1ELCasein kinase II subunit alpha2.7.11.10.449
3qlrNDPDihydrofolate reductase1.5.1.30.449
3r324CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.449
3sglFADtRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC/0.449
3w1tWRODihydroorotate dehydrogenase (fumarate)1.3.98.10.449
3wfjNAD2-dehydropantoate 2-reductase/0.449
4b8zNAPGDP-L-fucose synthase1.1.1.2710.449
4cdmFO1Deoxyribodipyrimidine photolyase/0.449
4dbzNDPPutative ketoacyl reductase1.3.10.449
4fj2NAP17beta-hydroxysteroid dehydrogenase/0.449
4wh3ATPN-acetylhexosamine 1-kinase2.7.1.1620.449
1uu9BI33-phosphoinositide-dependent protein kinase 12.7.11.10.448
1xe55FEPlasmepsin-23.4.23.390.448
2c3qGTXGlutathione S-transferase theta-12.5.1.180.448
2getCOKPantothenate kinase2.7.1.330.448
2ktdPUCProstaglandin-H2 D-isomerase5.3.99.20.448
2rl1UD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.448
3clsFADElectron transfer flavoprotein subunit alpha/0.448
3cr3ADPPTS-dependent dihydroxyacetone kinase, ADP-binding subunit DhaL2.70.448
3gkaFMNN-ethylmaleimide reductase/0.448
3h86AP5Adenylate kinase/0.448
3ndrNADPyridoxal 4-dehydrogenase1.1.1.1070.448
3nl6TPSUncharacterized protein/0.448
3qwbNDPProbable quinone oxidoreductase1.6.5.50.448
3umpATPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.448
5hg0SAMPantothenate synthetase/0.448
5iqiGNPBifunctional AAC/APH2.3.10.448
1cf3FADGlucose oxidase1.1.3.40.447
1egeFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.447
1g1aNADdTDP-glucose 4,6-dehydratase/0.447
1g41ADPATP-dependent protease ATPase subunit HslU/0.447
1kvsUPGUDP-glucose 4-epimerase5.1.3.20.447
1u1cBAUUridine phosphorylase2.4.2.30.447
2qocANPEphrin type-A receptor 32.7.10.10.447
2vnaNAPProstaglandin reductase 21.3.1.480.447
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.447
3elbC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.447
3gggNADPrephenate dehydrogenase/0.447
3jqpA2PFerredoxin--NADP reductase, apicoplast/0.447
3qbhQBHBeta-secretase 13.4.23.460.447
3r83Z14Cyclin-dependent kinase 22.7.11.220.447
3sptUD1Bifunctional protein GlmU/0.447
3vjoANPEpidermal growth factor receptor2.7.10.10.447
4b68NAPL-ornithine N(5)-monooxygenase/0.447
4nxuADPMitochondrial dynamics protein MID51/0.447
5a3bAPRSIR2 family protein/0.447
5lc1NADL-threonine 3-dehydrogenase/0.447
1bil0IURenin3.4.23.150.446
1bwlFMNNADPH dehydrogenase 11.6.99.10.446
1oaaNAPSepiapterin reductase1.1.1.1530.446
1p31EPUUDP-N-acetylmuramate--L-alanine ligase6.3.2.80.446
1y57MPZProto-oncogene tyrosine-protein kinase Src2.7.10.20.446
1zemNADXylitol dehydrogenase/0.446
2avvMK1Gag-Pol polyprotein3.4.23.160.446
2balPQAMitogen-activated protein kinase 14/0.446
2j9lATPH(+)/Cl(-) exchange transporter 5/0.446
2q2qNADBeta-D-hydroxybutyrate dehydrogenase/0.446
2vttLZDCyclin-dependent kinase 22.7.11.220.446
2vx17X8Ephrin type-B receptor 42.7.10.10.446
2xlsNAPPutative flavin-containing monooxygenase/0.446
2ztlNADD(-)-3-hydroxybutyrate dehydrogenase/0.446
3jziJZLBiotin carboxylase6.3.4.140.446
4dptAGSMevalonate diphosphate decarboxylase/0.446
4dpuAGSMevalonate diphosphate decarboxylase/0.446
4dymIYZActivin receptor type-12.7.11.300.446
4f32N323-oxoacyl-[acyl-carrier-protein] synthase 2/0.446
4friDWABeta-secretase 13.4.23.460.446
4jr7GNPCasein kinase II subunit alpha2.7.11.10.446
4kne1CYDihydrofolate reductase1.5.1.30.446
4kw51W6Decaprenylphosphoryl-beta-D-ribose oxidase/0.446
4mk928RGenome polyprotein2.7.7.480.446
4qms1N1Serine/threonine-protein kinase 242.7.11.10.446
4rf2NAPNADPH dependent R-specific alcohol dehydrogenase/0.446
1dr3HBIDihydrofolate reductase1.5.1.30.445
1h51FMNPentaerythritol tetranitrate reductase/0.445
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.445
1ndzFR5Adenosine deaminase3.5.4.40.445
1w4zNAPPutative ketoacyl reductase1.3.10.445
2ft9CHDFatty acid-binding protein 2, liver/0.445
2pzjNADPutative nucleotide sugar epimerase/ dehydratase/0.445
2xhd7T9Glutamate receptor 2/0.445
3c1tMYCDihydroflavonol 4-reductase1.1.1.2190.445
3coy53HPantothenate synthetase6.3.2.10.445
3ctyFADProbable thioredoxin reductase/0.445
3ixj586Beta-secretase 13.4.23.460.445
3oxfSAHHistone-lysine N-methyltransferase SMYD32.1.1.430.445
3ukfFDAUDP-galactopyranose mutase/0.445
3ukkFADUDP-galactopyranose mutase/0.445
3umoATPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.445
3uylTYDProbable NDP-rhamnosyltransferase/0.445
3zkyWT4Isopenicillin N synthase1.21.3.10.445
4ambDUDPutative glycosyl transferase/0.445
4jbiNDPAlcohol dehydrogenase (Zinc)/0.445
4q71FADBifunctional protein PutA/0.445
4rpjFADUDP-galactopyranose mutase5.4.99.90.445
4ycpFMNtRNA-dihydrouridine(16) synthase/0.445
5e92ANPTGF-beta receptor type-22.7.11.300.445
1bygSTUTyrosine-protein kinase CSK/0.444
1dhrNADDihydropteridine reductase1.5.1.340.444
1gcoNADGlucose 1-dehydrogenase1.1.1.470.444
1ju2FAD(R)-mandelonitrile lyase 24.1.2.100.444
1kbo340NAD(P)H dehydrogenase [quinone] 11.6.5.20.444
1n3sGTPGTP cyclohydrolase 13.5.4.160.444
1r6uTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.444
1snyNAPLD36273p/0.444
2d2iNAPGlyceraldehyde-3-phosphate dehydrogenase/0.444
2hq9FADMll6688 protein/0.444
2jb4A14Isopenicillin N synthase1.21.3.10.444
2npxFADNADH peroxidase1.11.1.10.444
2tctCTCTetracycline repressor protein class D/0.444
2xx91NFGlutamate receptor 2/0.444
3a7rLAQLipoate-protein ligase A6.3.1.200.444
3cvuFADRE11660p/0.444
3d91REMRenin3.4.23.150.444
3f03FMNPentaerythritol tetranitrate reductase/0.444
3qrwNDPPutative ketoacyl reductase1.3.10.444
3ru9NADUDP-N-acetylglucosamine 4-epimerase/0.444
3wbbNAPMeso-diaminopimelate D-dehydrogenase/0.444
4g95OAGDihydrofolate reductase1.5.1.30.444
4gid0GHBeta-secretase 13.4.23.460.444
4ijp1EHSerine/threonine-protein kinase PRP4 homolog2.7.11.10.444
4jnkZHKL-lactate dehydrogenase A chain1.1.1.270.444
5e8wSTUTGF-beta receptor type-12.7.11.300.444
1c70L75Protease/0.443
1h74AGSHomoserine kinase2.7.1.390.443
1mg5NAIAlcohol dehydrogenase1.1.1.10.443
1np7FADCryptochrome DASH/0.443
1o0sNAINAD-dependent malic enzyme, mitochondrial1.1.1.380.443
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.443
1xs7MMIBeta-secretase 13.4.23.460.443
2abbFMNPentaerythritol tetranitrate reductase/0.443
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.443
2ohvNHLGlutamate racemase/0.443
2ojtUBAGlutamate receptor ionotropic, kainate 1/0.443
2qs3UBEGlutamate receptor ionotropic, kainate 1/0.443
2x9dITCTetracycline repressor protein class D/0.443
2z4y252Geranylgeranyl pyrophosphate synthase/0.443
2zdt46CMitogen-activated protein kinase 102.7.11.240.443
3bbrBHYGlutamate receptor 2/0.443
3d84NDPDihydrofolate reductase1.5.1.30.443
3mdmFJZCholesterol 24-hydroxylase/0.443
3ms421NGlycogen phosphorylase, muscle form2.4.1.10.443
3td7FADProbable FAD-linked sulfhydryl oxidase R5961.8.3.20.443
3u4r08FGenome polyprotein2.7.7.480.443
4fh5UTPTerminal uridylyltransferase cid1/0.443
4fj1NAP17beta-hydroxysteroid dehydrogenase/0.443
4fuj1U9Urokinase-type plasminogen activator3.4.21.730.443
4yagNAIC alpha-dehydrogenase/0.443
1pr9NAPL-xylulose reductase1.1.1.100.442
1q43CMPPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2/0.442
2fsvNADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.442
2geuCOKPantothenate kinase2.7.1.330.442
2oapANPType II secretion system protein (GspE-2)/0.442
2omeNADC-terminal-binding protein 2/0.442
2pchSAHDiphthine synthase/0.442
2x7bCOAN-alpha-acetyltransferase2.3.10.442
2zb3NDPProstaglandin reductase 21.3.1.480.442
3bhiNAPCarbonyl reductase [NADPH] 11.1.1.1840.442
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
3gbuATPUncharacterized sugar kinase PH14592.7.10.442
3gstGPRGlutathione S-transferase Mu 12.5.1.180.442
3lpjZ75Beta-secretase 13.4.23.460.442
3qf9NM8Serine/threonine-protein kinase pim-12.7.11.10.442
3qfrFMNNADPH--cytochrome P450 reductase/0.442
3ruvANPChaperonin/0.442
4bfsZVSPantothenate kinase2.7.1.330.442
4cbqFADThioredoxin reductase/0.442
4d7mTDCTetracycline repressor protein class D/0.442
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.442
4kzoNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.442
4ocvANPAminoglycoside phosphotransferase/0.442
4riyADPEpidermal growth factor receptor2.7.10.10.442
4u7wNDPMxaA/0.442
5cnnANPEpidermal growth factor receptor2.7.10.10.442
5cpbNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
5d3qGDPDynamin-13.6.5.50.442
5fs7FADApoptosis-inducing factor 1, mitochondrial1.1.10.442
1dxyNADD-2-hydroxyisocaproate dehydrogenase1.1.10.441
1hzjUD1UDP-glucose 4-epimerase/0.441
1i3lGDUUDP-glucose 4-epimerase/0.441
1i3nUD1UDP-glucose 4-epimerase/0.441
1looGTPAdenylosuccinate synthetase isozyme 1/0.441
1mp0NADAlcohol dehydrogenase class-31.1.1.10.441
1qmfKEFPenicillin-binding protein 2x/0.441
1svmATPLarge T antigen3.6.40.441
1w4aAPCNTPase P4/0.441
1y0s331Peroxisome proliferator-activated receptor delta/0.441
2e77FMNLactate oxidase/0.441
2eixFADNADH-cytochrome b5 reductase/0.441
2hunNAD336aa long hypothetical dTDP-glucose 4,6-dehydratase/0.441
2rl2UD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.441
2wq6FADRE11660p/0.441
2y8qADP5'-AMP-activated protein kinase subunit gamma-1/0.441
3ad9NADSubunit alpha of sarocosine oxidase/0.441
3cvyFADRE11660p/0.441
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.441
3iaaTYDCalG2/0.441
3imgBZ2Pantothenate synthetase6.3.2.10.441
3p67FMNPentaerythritol tetranitrate reductase/0.441
3pce3HPProtocatechuate 3,4-dioxygenase alpha chain1.13.11.30.441
3pce3HPProtocatechuate 3,4-dioxygenase beta chain1.13.11.30.441
3pqbVGPPutative oxidoreductase/0.441
3rfxNADUronate dehydrogenase/0.441
3vweCOAAlpha-tubulin N-acetyltransferase 1/0.441
4fi1ATPCasein kinase II subunit alpha2.7.11.10.441
4fj0NAP17beta-hydroxysteroid dehydrogenase/0.441
4fryNADPutative signal-transduction protein with CBS domains/0.441
4imfSI3N-acetylneuraminate lyase/0.441
4jnkNAIL-lactate dehydrogenase A chain1.1.1.270.441
4m87NADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.441
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.441
4ockANPN-acetylhexosamine 1-kinase2.7.1.1620.441
4qysPLRTryptophan synthase beta chain 24.2.1.200.441
4rjeFNRLactate oxidase/0.441
4u0mATPCyclic GMP-AMP synthase/0.441
4yvz3ATDNA integrity scanning protein DisA/0.441
5kghACOPredicted acetyltransferase/0.441
6gswGPSGlutathione S-transferase Mu 12.5.1.180.441
1d0lBLGMembrane-bound lytic murein transglycosylase B4.2.2.n10.440
1ptjSNDNAD(P) transhydrogenase subunit alpha part 11.6.1.20.440
1udaUFGUDP-glucose 4-epimerase5.1.3.20.440
1xelUPGUDP-glucose 4-epimerase5.1.3.20.440
2b53D23Cyclin-dependent kinase 22.7.11.220.440
2dvlFADAcyl-CoA dehydrogenase/0.440
2gblATPCircadian clock protein kinase KaiC2.7.11.10.440
2nmtNHMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.440
2q4bNAPUncharacterized protein At5g02240/0.440
2tpsTPSThiamine-phosphate synthase/0.440
2wf4ZY4Beta-secretase 13.4.23.460.440
2wxvWXVCyclin-dependent kinase 22.7.11.220.440
2y3sTIRTamL/0.440
3iaeD7KBenzaldehyde lyase/0.440
3invNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.440
3kjrNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.440
3lsmSFDPyranose 2-oxidase/0.440
3nw3MU2Peptidoglycan recognition protein 1/0.440
3nx4NAPPutative oxidoreductase/0.440
3tdwGDPGentamicin resistance protein/0.440
3umvFADDeoxyribodipyrimidine photo-lyase4.1.99.30.440
3vnhFUUKelch-like ECH-associated protein 1/0.440
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.440
4is3NAD3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 21.17.98.10.440
4kwhNAPReductase homolog/0.440
4s1iPLPPyridoxal kinase, putative/0.440
4yxm2BADNA integrity scanning protein DisA/0.440
4z5wILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.440
5adhAPRAlcohol dehydrogenase E chain1.1.1.10.440