sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4qtn | NNR | Nicotinamide riboside transporter PnuC |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4qtn | NNR | Nicotinamide riboside transporter PnuC | / | 1.000 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.514 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.510 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.506 | |
| 1ypk | CCR | Prothrombin | 3.4.21.5 | 0.504 | |
| 3v2u | ATP | Protein GAL3 | / | 0.504 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.502 | |
| 1fml | RTL | Retinol dehydratase | / | 0.501 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.501 | |
| 2cn0 | F25 | Prothrombin | 3.4.21.5 | 0.501 | |
| 1r2j | FAD | FkbI | / | 0.496 | |
| 2zfq | 45U | Prothrombin | 3.4.21.5 | 0.496 | |
| 1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.495 | |
| 1thn | ADP | Anti-sigma F factor | / | 0.495 | |
| 2ay9 | 5PV | Aromatic-amino-acid aminotransferase | 2.6.1.57 | 0.495 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.494 | |
| 1sb1 | 165 | Prothrombin | 3.4.21.5 | 0.493 | |
| 2zc9 | 22U | Prothrombin | 3.4.21.5 | 0.493 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.493 | |
| 1c4v | IH2 | Prothrombin | 3.4.21.5 | 0.492 | |
| 4u16 | 3C0 | Muscarinic acetylcholine receptor M3 | / | 0.492 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.491 | |
| 4c49 | HCY | Corticosteroid-binding globulin | / | 0.491 | |
| 4k39 | SAM | Anaerobic sulfatase-maturating enzyme | 1.8.98 | 0.491 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.490 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.489 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.489 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.488 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.488 | |
| 1fvp | FMA | Non-fluorescent flavoprotein | / | 0.487 | |
| 2bdy | UNB | Prothrombin | 3.4.21.5 | 0.487 | |
| 2zda | 32U | Prothrombin | 3.4.21.5 | 0.487 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.486 | |
| 2hps | CTZ | Ca2+-triggered coelenterazine-binding protein 1 | / | 0.486 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.485 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.485 | |
| 3dha | C6L | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.485 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.485 | |
| 4k36 | SAM | Anaerobic sulfatase-maturating enzyme | 1.8.98 | 0.485 | |
| 1t4c | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.484 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.484 | |
| 1og4 | NAI | T-cell ecto-ADP-ribosyltransferase 2 | / | 0.483 | |
| 1til | ATP | Anti-sigma F factor | / | 0.483 | |
| 1ycg | FMN | Nitric oxide reductase | 1 | 0.483 | |
| 4ax9 | N5N | Prothrombin | 3.4.21.5 | 0.483 | |
| 2zhf | 49U | Prothrombin | 3.4.21.5 | 0.482 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.482 | |
| 2ipj | FFA | Aldo-keto reductase family 1 member C2 | / | 0.481 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.481 | |
| 3p17 | 99P | Prothrombin | 3.4.21.5 | 0.481 | |
| 1c4y | IH3 | Prothrombin | 3.4.21.5 | 0.480 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.480 | |
| 1ypl | RA8 | Prothrombin | 3.4.21.5 | 0.480 | |
| 3qto | 10P | Prothrombin | 3.4.21.5 | 0.480 | |
| 3zc3 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.480 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.480 | |
| 4bj9 | UHB | Tankyrase-2 | 2.4.2.30 | 0.479 | |
| 1u1g | BBB | Uridine phosphorylase | 2.4.2.3 | 0.478 | |
| 2anm | CDO | Prothrombin | 3.4.21.5 | 0.478 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.478 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.477 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.477 | |
| 2bn4 | FMN | NADPH--cytochrome P450 reductase | / | 0.477 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.477 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.477 | |
| 3keq | NAD | Redox-sensing transcriptional repressor Rex | / | 0.477 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.477 | |
| 4j7h | TRH | PCZA361.3 | / | 0.477 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.476 | |
| 2r2m | I50 | Prothrombin | 3.4.21.5 | 0.476 | |
| 1icq | OPD | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.475 | |
| 2hxz | H7J | Cathepsin S | 3.4.22.27 | 0.475 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.475 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.475 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.475 | |
| 3qtv | 06P | Prothrombin | 3.4.21.5 | 0.475 | |
| 1nzq | 162 | Prothrombin | 3.4.21.5 | 0.474 | |
| 1uae | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.474 | |
| 3wtk | TH4 | Acetylcholine-binding protein | / | 0.474 | |
| 1pwy | AC2 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.473 | |
| 1v3q | 2DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.473 | |
| 2wgg | TLM | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.473 | |
| 3ppk | FNI | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.473 | |
| 4n82 | FMN | Ribonucleotide reductase (NrdI family protein), putative | / | 0.473 | |
| 1xm1 | GAH | Prothrombin | 3.4.21.5 | 0.472 | |
| 3clx | X22 | E3 ubiquitin-protein ligase XIAP | 6.3.2 | 0.472 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.472 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.471 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.471 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.471 | |
| 2aou | CQA | Histamine N-methyltransferase | 2.1.1.8 | 0.471 | |
| 2e17 | SAH | Diphthine synthase | / | 0.471 | |
| 2jh5 | 895 | Prothrombin | 3.4.21.5 | 0.471 | |
| 3c27 | DKK | Prothrombin | 3.4.21.5 | 0.471 | |
| 1el4 | CTZ | Obelin | / | 0.470 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 3lfz | ADP | Uncharacterized protein MJ1225 | / | 0.470 | |
| 3qwc | 98P | Prothrombin | 3.4.21.5 | 0.470 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.470 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.470 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.470 | |
| 1d9i | 00P | Prothrombin | 3.4.21.5 | 0.469 | |
| 1jqd | SAH | Histamine N-methyltransferase | 2.1.1.8 | 0.469 | |
| 1r6u | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.469 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 2eh5 | SAH | Diphthine synthase | / | 0.469 | |
| 2zb8 | IMN | Prostaglandin reductase 2 | 1.3.1.48 | 0.469 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.469 | |
| 3ho9 | N3A | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.469 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.469 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.469 | |
| 3pz2 | 3PZ | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.469 | |
| 3wth | IM4 | Acetylcholine-binding protein | / | 0.469 | |
| 1ygk | RRC | Pyridoxal kinase | 2.7.1.35 | 0.468 | |
| 3c1o | NAP | Eugenol synthase | / | 0.468 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 4irn | FAD | AnaB | / | 0.468 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.467 | |
| 1ppj | ANY | Cytochrome b | / | 0.467 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.467 | |
| 2ejz | SAH | Diphthine synthase | / | 0.467 | |
| 3c4h | DRL | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.467 | |
| 3w5h | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.467 | |
| 3zhv | TDW | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.467 | |
| 4r1f | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.467 | |
| 1d3p | BT3 | Prothrombin | 3.4.21.5 | 0.466 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 1ja0 | FMN | NADPH--cytochrome P450 reductase | / | 0.466 | |
| 1odj | GMP | Purine nucleoside phosphorylase | / | 0.466 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 1xp8 | AGS | Protein RecA | / | 0.466 | |
| 1y6o | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.466 | |
| 2aq7 | TL5 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.466 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 2xys | SY9 | Soluble acetylcholine receptor | / | 0.466 | |
| 3bi6 | 396 | Wee1-like protein kinase | 2.7.10.2 | 0.466 | |
| 4ajf | F03 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.466 | |
| 4s1i | PLP | Pyridoxal kinase, putative | / | 0.466 | |
| 4x5f | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 4xo7 | ASD | Aldo-keto reductase family 1 member C2 | / | 0.466 | |
| 1jwt | BLI | Prothrombin | 3.4.21.5 | 0.465 | |
| 1udt | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.465 | |
| 1z71 | L17 | Prothrombin | 3.4.21.5 | 0.465 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.465 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.465 | |
| 3dhc | CYK | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.465 | |
| 4ixd | 1HV | Integrin alpha-L | / | 0.465 | |
| 4qoh | STL | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.465 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 2huq | SAH | Diphthine synthase | / | 0.464 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.464 | |
| 2zfr | 46U | Prothrombin | 3.4.21.5 | 0.464 | |
| 3cb2 | GDP | Tubulin gamma-1 chain | / | 0.464 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 3nhl | YTR | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.464 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.464 | |
| 4f3g | KAI | Glutamate receptor 3 | / | 0.464 | |
| 4gv2 | 5ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.464 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.463 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 1kyv | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.463 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 1oyt | FSN | Prothrombin | 3.4.21.5 | 0.463 | |
| 1s36 | CEI | Obelin | / | 0.463 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.463 | |
| 1ypg | UIR | Prothrombin | 3.4.21.5 | 0.463 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.463 | |
| 2p6l | SAH | Diphthine synthase | / | 0.463 | |
| 2zi2 | 24U | Prothrombin | 3.4.21.5 | 0.463 | |
| 3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.463 | |
| 4heu | 15J | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.463 | |
| 4uaj | FAD | Na(+)-translocating NADH-quinone reductase subunit F | / | 0.463 | |
| 4zzj | CNA | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.463 | |
| 1dr4 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 1enp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic | 1.3.1.9 | 0.462 | |
| 1u71 | MXA | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 2a2x | NA9 | Prothrombin | 3.4.21.5 | 0.462 | |
| 2in6 | 839 | Wee1-like protein kinase | 2.7.10.2 | 0.462 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.462 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.462 | |
| 2zgx | 29U | Prothrombin | 3.4.21.5 | 0.462 | |
| 3c35 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.462 | |
| 3d4b | DZD | NAD-dependent protein deacetylase | / | 0.462 | |
| 3zec | ANP | Adenosine monophosphate-protein transferase SoFic | 2.7.7.n1 | 0.462 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.462 | |
| 4oex | 5EO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.462 | |
| 1mrq | STR | Aldo-keto reductase family 1 member C1 | / | 0.461 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.461 | |
| 1xmm | M7G | m7GpppX diphosphatase | 3.6.1.59 | 0.461 | |
| 2acw | UPG | Glycosyltransferase | / | 0.461 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.461 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.461 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.461 | |
| 2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.461 | |
| 3c1t | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.461 | |
| 4cax | 646 | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.461 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.461 | |
| 4i9z | 5BA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.461 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.460 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.460 | |
| 2zff | 53U | Prothrombin | 3.4.21.5 | 0.460 | |
| 2zgb | 21U | Prothrombin | 3.4.21.5 | 0.460 | |
| 2zhq | 27U | Prothrombin | 3.4.21.5 | 0.460 | |
| 3dge | ADP | Sensor histidine kinase | / | 0.460 | |
| 3g5i | DNB | Pyrimidine-specific ribonucleoside hydrolase RihA | / | 0.460 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.460 | |
| 3ufl | 508 | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.460 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.460 | |
| 4fwe | FAD | Lysine-specific histone demethylase 1B | 1 | 0.460 | |
| 4i6f | 1C7 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.460 | |
| 4wbd | ADP | Putative cysteine ligase BshC | / | 0.460 | |
| 5cmx | 0G6 | Prothrombin | 3.4.21.5 | 0.460 | |
| 5dp2 | NAP | CurF | / | 0.460 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.459 | |
| 2eeq | SAH | Diphthine synthase | / | 0.459 | |
| 2ejk | SAH | Diphthine synthase | / | 0.459 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.459 | |
| 2nmt | MIM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.459 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.459 | |
| 3qvr | FAD | Glucose oxidase | 1.1.3.4 | 0.459 | |
| 3vo2 | FAD | Ferredoxin--NADP reductase | / | 0.459 | |
| 3zia | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.459 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.459 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.459 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.459 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.459 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.459 | |
| 4x7u | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.459 | |
| 4xwt | U5P | Ribonuclease J | / | 0.459 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.458 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.458 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.458 | |
| 1jdz | FMB | Purine nucleoside phosphorylase | / | 0.458 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 1pr4 | MTP | Purine nucleoside phosphorylase DeoD-type | / | 0.458 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.458 | |
| 2p6i | SAH | Diphthine synthase | / | 0.458 | |
| 2p9d | SAH | Diphthine synthase | / | 0.458 | |
| 2znk | 31U | Prothrombin | 3.4.21.5 | 0.458 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.458 | |
| 3biz | 61E | Wee1-like protein kinase | 2.7.10.2 | 0.458 | |
| 3bw2 | FMN | Putative 2-nitropropane dioxygenase | / | 0.458 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 3ojx | FAD | NADPH--cytochrome P450 reductase | / | 0.458 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.458 | |
| 4bb2 | STR | Corticosteroid-binding globulin | / | 0.458 | |
| 4k38 | SAM | Anaerobic sulfatase-maturating enzyme | 1.8.98 | 0.458 | |
| 5fmm | MGT | Polymerase basic protein 2 | / | 0.458 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 1w6j | R71 | Lanosterol synthase | 5.4.99.7 | 0.457 | |
| 1x8b | 824 | Wee1-like protein kinase | 2.7.10.2 | 0.457 | |
| 1ypm | RA4 | Prothrombin | 3.4.21.5 | 0.457 | |
| 2dsh | SAH | Diphthine synthase | / | 0.457 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.457 | |
| 3c36 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.457 | |
| 3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.457 | |
| 3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.457 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.457 | |
| 3n3b | FMN | Protein NrdI | / | 0.457 | |
| 4ajm | 3A6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.457 | |
| 4dbu | BT9 | Aldo-keto reductase family 1 member C3 | / | 0.457 | |
| 4yaw | 2AM | NADPH--cytochrome P450 reductase | / | 0.457 | |
| 4zow | CLM | Multidrug transporter MdfA | / | 0.457 | |
| 1nhk | CMP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.456 | |
| 1nqu | RDL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.456 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.456 | |
| 1qv0 | CZH | Obelin | / | 0.456 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.456 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.456 | |
| 2bjs | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 2eni | SAH | Diphthine synthase | / | 0.456 | |
| 2gev | COK | Pantothenate kinase | 2.7.1.33 | 0.456 | |
| 2gvc | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.456 | |
| 2hxd | DUP | dCTP deaminase, dUMP-forming | 3.5.4.30 | 0.456 | |
| 2pca | SAH | Diphthine synthase | / | 0.456 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 2xf3 | J01 | Uncharacterized protein | / | 0.456 | |
| 3c49 | KU8 | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.456 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.456 | |
| 4k37 | SAM | Anaerobic sulfatase-maturating enzyme | 1.8.98 | 0.456 | |
| 4u14 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.456 | |
| 1h35 | R01 | Squalene--hopene cyclase | 4.2.1.129 | 0.455 | |
| 1h42 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.455 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.455 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.455 | |
| 2rdn | 1PL | 1-deoxypentalenic acid 11-beta-hydroxylase | 1.14.11.35 | 0.455 | |
| 2uuk | 897 | Prothrombin | 3.4.21.5 | 0.455 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.455 | |
| 2zfp | 19U | Prothrombin | 3.4.21.5 | 0.455 | |
| 3b1p | NOS | PfkB carbohydrate kinase family protein | / | 0.455 | |
| 3gey | P34 | Poly [ADP-ribose] polymerase 15 | 2.4.2.30 | 0.455 | |
| 3qe2 | FAD | NADPH--cytochrome P450 reductase | / | 0.455 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.455 | |
| 4a1o | AMZ | Bifunctional purine biosynthesis protein PurH | 2.1.2.3 | 0.455 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
| 4f0e | 0RU | Poly [ADP-ribose] polymerase 15 | 2.4.2.30 | 0.455 | |
| 4r81 | FMN | Predicted NADH dehydrogenase | / | 0.455 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.455 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.454 | |
| 1umk | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.454 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.454 | |
| 2jh0 | 701 | Prothrombin | 3.4.21.5 | 0.454 | |
| 2ziq | 26U | Prothrombin | 3.4.21.5 | 0.454 | |
| 3ce0 | P34 | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.454 | |
| 3cr0 | 809 | Wee1-like protein kinase | 2.7.10.2 | 0.454 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 3wi2 | P98 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.454 | |
| 4kp7 | 1UQ | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.454 | |
| 4n8i | COA | Putative 4-hydroxybutyrate coenzyme A transferase | / | 0.454 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.454 | |
| 1aqu | EST | Estrogen sulfotransferase, testis isoform | 2.8.2.4 | 0.453 | |
| 1gjr | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.453 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 1q5d | EPB | Epothilone C/D epoxidase | 1.14 | 0.453 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.453 | |
| 1u2r | SO1 | Elongation factor 2 | / | 0.453 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.453 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.453 | |
| 3w5u | FAD | Ferredoxin | / | 0.453 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.453 | |
| 4b2g | V1N | Uncharacterized protein | / | 0.453 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.453 | |
| 4iae | 1DX | Alr2278 protein | / | 0.453 | |
| 4qem | HC4 | Phospholipase A2 VRV-PL-VIIIa | / | 0.453 | |
| 4y7c | FAD | NADPH--cytochrome P450 reductase | / | 0.453 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.452 | |
| 1h85 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.452 | |
| 1t13 | INI | 6,7-dimethyl-8-ribityllumazine synthase 2 | / | 0.452 | |
| 1vce | SAH | Diphthine synthase | / | 0.452 | |
| 2e16 | SAH | Diphthine synthase | / | 0.452 | |
| 2emu | SAH | Diphthine synthase | / | 0.452 | |
| 2g0l | FLN | Neocarzinostatin | / | 0.452 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.452 | |
| 2v2z | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.452 | |
| 3bl7 | DD1 | m7GpppX diphosphatase | 3.6.1.59 | 0.452 | |
| 3fr4 | F8A | Fatty acid-binding protein, adipocyte | / | 0.452 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.452 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.452 | |
| 3lxe | TOR | Carbonic anhydrase 1 | 4.2.1.1 | 0.452 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.452 | |
| 4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.452 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.452 | |
| 4rn6 | 15U | Prothrombin | 3.4.21.5 | 0.452 | |
| 4tjy | 3GN | Tankyrase-2 | 2.4.2.30 | 0.452 | |
| 4x5g | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 4yao | FAD | NADPH--cytochrome P450 reductase | / | 0.452 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.451 | |
| 1k7l | 544 | Peroxisome proliferator-activated receptor alpha | / | 0.451 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.451 | |
| 1qpl | 587 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.451 | |
| 1tll | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.451 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.451 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.451 | |
| 1zdw | FLV | Prenyltransferase | / | 0.451 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 2lfo | GCH | Fatty acid-binding protein, liver | / | 0.451 | |
| 2v3o | I26 | Prothrombin | 3.4.21.5 | 0.451 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 2yp0 | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.451 | |
| 3ikt | NAD | Redox-sensing transcriptional repressor Rex | / | 0.451 | |
| 3qfr | FAD | NADPH--cytochrome P450 reductase | / | 0.451 | |
| 3vil | SA0 | Beta-glucosidase | / | 0.451 | |
| 4c2z | 646 | Glycylpeptide N-tetradecanoyltransferase 1 | / | 0.451 | |
| 4dbw | 511 | Aldo-keto reductase family 1 member C3 | / | 0.451 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.451 | |
| 1amo | FMN | NADPH--cytochrome P450 reductase | / | 0.450 | |
| 1gg5 | E09 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1v35 | NAI | Enoyl-ACP reductase | / | 0.450 | |
| 1w1w | AGS | Structural maintenance of chromosomes protein 1 | / | 0.450 | |
| 1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.450 | |
| 2a9z | 26A | Adenosine kinase | 2.7.1.20 | 0.450 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.450 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.450 | |
| 2w6o | OA3 | Biotin carboxylase | 6.3.4.14 | 0.450 | |
| 2yg4 | FAD | Putrescine oxidase | / | 0.450 | |
| 2zg0 | 50U | Prothrombin | 3.4.21.5 | 0.450 | |
| 3eks | CY9 | Actin-5C | / | 0.450 | |
| 3eku | CY9 | Actin-5C | / | 0.450 | |
| 3fsj | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.450 | |
| 3hii | PNT | Amiloride-sensitive amine oxidase [copper-containing] | / | 0.450 | |
| 3hk1 | B64 | Fatty acid-binding protein, adipocyte | / | 0.450 | |
| 3sf6 | FDA | Glutaryl-CoA dehydrogenase | / | 0.450 | |
| 4a16 | H34 | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 4gts | 7TP | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.450 | |
| 4xmx | BES | Aminopeptidase N | 3.4.11.2 | 0.450 | |
| 1jnr | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.449 | |
| 1jra | FAD | FAD-linked sulfhydryl oxidase ERV2 | 1.8.3.2 | 0.449 | |
| 1mu8 | CDB | Prothrombin | 3.4.21.5 | 0.449 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.449 | |
| 1re0 | AFB | ADP-ribosylation factor 1 | / | 0.449 | |
| 1re0 | AFB | ARF guanine-nucleotide exchange factor 1 | / | 0.449 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.449 | |
| 1xf0 | ASD | Aldo-keto reductase family 1 member C3 | / | 0.449 | |
| 2c1z | KMP | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.449 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 2pau | D5M | 5'-deoxynucleotidase YfbR | / | 0.449 | |
| 2x86 | ADP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.449 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.449 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.449 | |
| 3oji | PYV | Abscisic acid receptor PYL3 | / | 0.449 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.449 | |
| 4a3u | FMN | NADH:flavin oxidoreductase/NADH oxidase | / | 0.449 | |
| 4bam | MM9 | Prothrombin | 3.4.21.5 | 0.449 | |
| 4bjb | P34 | Tankyrase-2 | 2.4.2.30 | 0.449 | |
| 4jhi | EMU | Nodulin-13 | / | 0.449 | |
| 4jsr | 1NQ | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.449 | |
| 4li6 | 1XO | Tankyrase-1 | 2.4.2.30 | 0.449 | |
| 1eno | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic | 1.3.1.9 | 0.448 | |
| 1gaq | FAD | Ferredoxin | / | 0.448 | |
| 1o5g | CR9 | Prothrombin | 3.4.21.5 | 0.448 | |
| 1ogj | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.448 | |
| 1qh0 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.448 | |
| 1rx0 | FAD | Isobutyryl-CoA dehydrogenase, mitochondrial | 1.3.99 | 0.448 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.448 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.448 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 2qw8 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.448 | |
| 2vtd | LKM | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.448 | |
| 2yg3 | FAD | Putrescine oxidase | / | 0.448 | |
| 2yx6 | ADP | Uncharacterized protein | / | 0.448 | |
| 3fr2 | 8CA | Fatty acid-binding protein, adipocyte | / | 0.448 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.448 | |
| 3n39 | FMN | Protein NrdI | / | 0.448 | |
| 3prf | FP3 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.448 | |
| 3q7f | ED2 | Uncharacterized protein | / | 0.448 | |
| 3qfc | FAD | NADPH--cytochrome P450 reductase | / | 0.448 | |
| 3uk6 | ADP | RuvB-like 2 | 3.6.4.12 | 0.448 | |
| 3zht | TD9 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.448 | |
| 5iqf | GDP | Bifunctional AAC/APH | 2.3.1 | 0.448 | |
| 1lvu | 9PP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.447 | |
| 1q23 | FUA | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.447 | |
| 1u1d | 181 | Uridine phosphorylase | 2.4.2.3 | 0.447 | |
| 2e07 | SAH | Diphthine synthase | / | 0.447 | |
| 2e8u | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.447 | |
| 2p6d | SAH | Diphthine synthase | / | 0.447 | |
| 2po3 | T4K | 4-dehydrase | / | 0.447 | |
| 2wjo | QUD | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.447 | |
| 3l3l | L3L | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.447 | |
| 3rbq | GLY_ALA_GLY_ALA_DAO | Protein unc-119 homolog A | / | 0.447 | |
| 3wav | DWV | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | 3.1.4.39 | 0.447 | |
| 4a2z | VIQ | Glycylpeptide N-tetradecanoyltransferase | / | 0.447 | |
| 4c71 | 7RD | 3-oxoacyl-ACP synthase | / | 0.447 | |
| 4fri | DWA | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4ge9 | 0L0 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.447 | |
| 4jt9 | 1NS | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.447 | |
| 4wdf | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.447 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.447 | |
| 5fd8 | A5A | Putative carboxypeptidase yocD | / | 0.447 | |
| 1c4u | IH1 | Prothrombin | 3.4.21.5 | 0.446 | |
| 1jqi | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | / | 0.446 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.446 | |
| 1n8w | COA | Malate synthase G | / | 0.446 | |
| 1pua | COA | HAT A1 | / | 0.446 | |
| 1ry8 | RUT | Aldo-keto reductase family 1 member C3 | / | 0.446 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.446 | |
| 2b3d | FAD | Modulator of drug activity B | / | 0.446 | |
| 2flh | ZEA | Cytokinin-specific binding protein | / | 0.446 | |
| 2owu | SAH | Diphthine synthase | / | 0.446 | |
| 2w6p | OA4 | Biotin carboxylase | 6.3.4.14 | 0.446 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.446 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3maa | FKP | Adenylate cyclase type 2 | / | 0.446 | |
| 3maa | FKP | Adenylate cyclase type 5 | / | 0.446 | |
| 4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.446 | |
| 4b65 | NDP | L-ornithine N(5)-monooxygenase | / | 0.446 | |
| 4h6p | FMN | Chromate reductase | / | 0.446 | |
| 4ho6 | UTP | Glucose-1-phosphate thymidylyltransferase | / | 0.446 | |
| 4tnz | TTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.446 | |
| 4wqm | FAD | Toluene-4-monooxygenase electron transfer component | 1.18.1.3 | 0.446 | |
| 1bx1 | FAD | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 0.445 | |
| 1gaw | FAD | Ferredoxin | / | 0.445 | |
| 1gpn | HUB | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.445 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.445 | |
| 2acl | L05 | Oxysterols receptor LXR-alpha | / | 0.445 | |
| 2e15 | SAH | Diphthine synthase | / | 0.445 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.445 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.445 | |
| 2h21 | SAM | Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic | 2.1.1.127 | 0.445 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.445 | |
| 2zdv | 37U | Prothrombin | 3.4.21.5 | 0.445 | |
| 2zs9 | ADP | Pantothenate kinase | 2.7.1.33 | 0.445 | |
| 3c15 | FOK | Adenylate cyclase type 2 | / | 0.445 | |
| 3c15 | FOK | Adenylate cyclase type 5 | / | 0.445 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3gjw | GJW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.445 | |
| 3hzi | ATP | Serine/threonine-protein kinase toxin HipA | / | 0.445 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.445 | |
| 3ojw | FMN | NADPH--cytochrome P450 reductase | / | 0.445 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.445 | |
| 4b66 | NAP | L-ornithine N(5)-monooxygenase | / | 0.445 | |
| 4lb2 | DM5 | Serum albumin | / | 0.445 | |
| 4wfr | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.445 | |
| 5d6l | CAU | Beta-2 adrenergic receptor | / | 0.445 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 1mue | CDD | Prothrombin | 3.4.21.5 | 0.444 | |
| 1p91 | SAM | 23S rRNA (guanine(745)-N(1))-methyltransferase | / | 0.444 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.444 | |
| 1sq5 | ADP | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 1uk1 | FRQ | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.444 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 1xds | DRA | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.444 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.444 | |
| 2fap | RAD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.444 | |
| 2fap | RAD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.444 | |
| 2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.444 | |
| 2nnq | T4B | Fatty acid-binding protein, adipocyte | / | 0.444 | |
| 2on6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.444 | |
| 2qqf | A1R | NAD-dependent protein deacetylase HST2 | 3.5.1 | 0.444 | |
| 2v57 | PRL | TetR family transcriptional regulator | / | 0.444 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 2zhw | 12U | Prothrombin | 3.4.21.5 | 0.444 | |
| 3gc4 | AAQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.444 | |
| 3nub | UD0 | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.444 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.444 | |
| 4b1e | 6T6 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4dk7 | 0KS | Oxysterols receptor LXR-beta | / | 0.444 | |
| 4paa | THG | Dimethylglycine dehydrogenase, mitochondrial | 1.5.8.4 | 0.444 | |
| 4qfx | DGT | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.444 | |
| 4utl | FNR | Xenobiotic reductase | / | 0.444 | |
| 1evj | NAD | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.443 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.443 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 1ta6 | 177 | Prothrombin | 3.4.21.5 | 0.443 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.443 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.443 | |
| 2bn4 | FAD | NADPH--cytochrome P450 reductase | / | 0.443 | |
| 2fzj | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 2vrb | NAP | Triphenylmethane reductase | / | 0.443 | |
| 2w8y | 486 | Progesterone receptor | / | 0.443 | |
| 2wmd | ZZ0 | NmrA-like family domain-containing protein 1 | / | 0.443 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.443 | |
| 3ddw | 055 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.443 | |
| 3dhk | 23U | Prothrombin | 3.4.21.5 | 0.443 | |
| 3djl | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.443 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3fpk | FAD | Ferredoxin-NADP reductase | / | 0.443 | |
| 3p2o | NAD | Bifunctional protein FolD | / | 0.443 | |
| 3sfx | JAN | Uncharacterized protein | / | 0.443 | |
| 3zhu | TD8 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.443 | |
| 4af7 | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.443 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.443 | |
| 4bfs | ZVS | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 4br0 | AU1 | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.443 | |
| 4drh | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.443 | |
| 4drh | RAP | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.443 | |
| 4f7i | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.443 | |
| 4g2r | H1L | Probable propionyl-CoA carboxylase beta chain 6 | 6.4.1.3 | 0.443 | |
| 5dsy | UHB | Poly [ADP-ribose] polymerase 2 | 2.4.2.30 | 0.443 | |
| 1dmw | HBI | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.442 | |
| 1g60 | SAM | Modification methylase MboII | 2.1.1.72 | 0.442 | |
| 1g7u | PEP | 2-dehydro-3-deoxyphosphooctonate aldolase | 2.5.1.55 | 0.442 | |
| 1hvy | D16 | Thymidylate synthase | 2.1.1.45 | 0.442 | |
| 1kms | LIH | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1sui | FRE | Caffeoyl-CoA O-methyltransferase | 2.1.1.104 | 0.442 | |
| 1tl7 | ONM | Adenylate cyclase type 2 | / | 0.442 | |
| 1tl7 | ONM | Adenylate cyclase type 5 | / | 0.442 | |
| 1tou | B1V | Fatty acid-binding protein, adipocyte | / | 0.442 | |
| 2bf4 | FAD | NADPH--cytochrome P450 reductase | / | 0.442 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.442 | |
| 2ipi | AKY | Aclacinomycin-N/aclacinomycin-A oxidase | / | 0.442 | |
| 2ok8 | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.442 | |
| 2pch | SAH | Diphthine synthase | / | 0.442 | |
| 2r0c | FAD | Putative FAD-monooxygenase | / | 0.442 | |
| 2vqq | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.442 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 3cge | COA | Coenzyme A disulfide reductase | / | 0.442 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 3fzn | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.442 | |
| 3hy9 | 098 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.442 | |
| 3ojx | FMN | NADPH--cytochrome P450 reductase | / | 0.442 | |
| 3q8u | ADP | Nucleoside diphosphate kinase | / | 0.442 | |
| 3r7m | SUZ | Aldo-keto reductase family 1 member C3 | / | 0.442 | |
| 3u57 | DH8 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.442 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.442 | |
| 4b63 | NAP | L-ornithine N(5)-monooxygenase | / | 0.442 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 4dbs | 0HV | Aldo-keto reductase family 1 member C3 | / | 0.442 | |
| 4g2w | NI0 | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.442 | |
| 4h7c | 10H | Aldo-keto reductase family 1 member C3 | / | 0.442 | |
| 4hhz | 15S | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.442 | |
| 4lxk | 1YT | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4u07 | ATP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.442 | |
| 1beu | IPL | Tryptophan synthase alpha chain | / | 0.441 | |
| 1e64 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.441 | |
| 1fnb | FAD | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 0.441 | |
| 1mcz | RMN | Benzoylformate decarboxylase | 4.1.1.7 | 0.441 | |
| 1ni1 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.441 | |
| 1o2g | 696 | Prothrombin | 3.4.21.5 | 0.441 | |
| 1ogi | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.441 | |
| 1rkw | PNT | HTH-type transcriptional regulator QacR | / | 0.441 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.441 | |
| 1t4v | 14A | Prothrombin | 3.4.21.5 | 0.441 | |
| 1w87 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.441 | |
| 1yry | MSG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 2e99 | B08 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.441 | |
| 2eld | SAH | Diphthine synthase | / | 0.441 | |
| 2f38 | 15M | Aldo-keto reductase family 1 member C3 | / | 0.441 | |
| 2hut | SAH | Diphthine synthase | / | 0.441 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.441 | |
| 2qjp | ANJ | Cytochrome b | / | 0.441 | |
| 2re8 | GSU | Glutamine--tRNA ligase | 6.1.1.18 | 0.441 | |
| 2toh | HBI | Tyrosine 3-monooxygenase | 1.14.16.2 | 0.441 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.441 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.441 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 3hwx | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.441 | |
| 3jq6 | DX1 | Pteridine reductase, putative | / | 0.441 | |
| 3p84 | FMN | Pentaerythritol tetranitrate reductase | / | 0.441 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.441 | |
| 4b67 | NAP | L-ornithine N(5)-monooxygenase | / | 0.441 | |
| 4dyp | 0MS | Nucleoprotein | / | 0.441 | |
| 4eb5 | PLP | Cysteine desulfurase IscS 2 | / | 0.441 | |
| 4epq | 0RR | Poly(ADP-ribose) glycohydrolase | / | 0.441 | |
| 4ez8 | DHF | Thymidylate synthase | 2.1.1.45 | 0.441 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.441 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.441 | |
| 4nqg | CZH | Mitrocomin | / | 0.441 | |
| 4to4 | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.441 | |
| 4x7z | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.441 | |
| 4zgs | NAD | Putative D-lactate dehydrogenase | / | 0.441 | |
| 1c7o | PPG | Hemolysin | / | 0.440 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.440 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.440 | |
| 1e2n | RCA | Thymidine kinase | / | 0.440 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.440 | |
| 1h66 | RH1 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 1re7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1sg0 | STL | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.440 | |
| 1toj | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.440 | |
| 1uyi | PUZ | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.440 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.440 | |
| 2dr3 | ADP | UPF0273 protein PH0284 | / | 0.440 | |
| 2dvo | ITT | dITP/XTP pyrophosphatase | 3.6.1.19 | 0.440 | |
| 2fa3 | ACO | Hydroxymethylglutaryl-CoA synthase | / | 0.440 | |
| 2gg0 | U11 | Methionine aminopeptidase | / | 0.440 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.440 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.440 | |
| 2pks | G44 | Prothrombin | 3.4.21.5 | 0.440 | |
| 2wba | FAD | Trypanothione reductase | 1.8.1.12 | 0.440 | |
| 2yg5 | FAD | Putrescine oxidase | / | 0.440 | |
| 3fow | IMH | Purine nucleoside phosphorylase | / | 0.440 | |
| 3gcn | TYR_GLN_PHE | Serine endoprotease DegS | 3.4.21.107 | 0.440 | |
| 3jyq | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.440 | |
| 3kp4 | MII | Transcriptional regulator TcaR | / | 0.440 | |
| 3r8h | ZOM | Aldo-keto reductase family 1 member C3 | / | 0.440 | |
| 3rup | ADP | Biotin carboxylase | 6.3.4.14 | 0.440 | |
| 3std | MQ0 | Scytalone dehydratase | 4.2.1.94 | 0.440 | |
| 4c6z | TLE | 3-oxoacyl-ACP synthase | / | 0.440 | |
| 4eqw | COA | Coenzyme A disulfide reductase | / | 0.440 | |
| 4fam | 0SZ | Aldo-keto reductase family 1 member C3 | / | 0.440 | |
| 4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.440 | |
| 5ein | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.440 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.440 |