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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4o7nADPPhosphoribosylaminoimidazole-succinocarboxamide synthase6.3.2.6

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4o7nADPPhosphoribosylaminoimidazole-succinocarboxamide synthase6.3.2.61.000
2ywvADPPhosphoribosylaminoimidazole-succinocarboxamide synthase/0.600
4fgrADPPhosphoribosylaminoimidazole-succinocarboxamide synthase6.3.2.60.587
4o7lADPPhosphoribosylaminoimidazole-succinocarboxamide synthase6.3.2.60.561
4nyeADPPhosphoribosylaminoimidazole-succinocarboxamide synthase6.3.2.60.511
1wuuANPGalactokinase2.7.1.60.507
1z6tADPApoptotic protease-activating factor 1/0.499
4l8u9AZSerum albumin/0.498
3l6jZ90Alr2278 protein/0.496
3mqe416Prostaglandin G/H synthase 21.14.99.10.496
2x7hPFNProstaglandin reductase 310.494
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.493
4ge70K5Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.490
4xiwAZMCarbonic anhydrase, alpha type/0.490
2z02ATPPhosphoribosylaminoimidazole-succinocarboxamide synthase6.3.2.60.489
3cgbCOACoenzyme A disulfide reductase/0.488
2jbsFMNp-hydroxyphenylacetate 3-hydroxylase, oxygenase component/0.485
4zgsNADPutative D-lactate dehydrogenase/0.485
4p5fAR6Inosine-uridine nucleoside N-ribohydrolase/0.484
1kquBR4Phospholipase A2, membrane associated/0.483
2g37FADProline dehydrogenase/0.480
4l5b1UXDeoxycytidine kinase2.7.1.740.480
1fx9MJIPhospholipase A2, major isoenzyme3.1.1.40.479
3sf6FDAGlutaryl-CoA dehydrogenase/0.479
4cukNAID-lactate dehydrogenase/0.479
1vceSAHDiphthine synthase/0.476
2hk9NAPShikimate dehydrogenase (NADP(+))/0.476
2jn3JN3Fatty acid-binding protein, liver/0.475
3bnkFMNFlavoredoxin/0.475
1jm6ADP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial2.7.11.20.474
2b7aIZATyrosine-protein kinase JAK2/0.474
2v9jATP5'-AMP-activated protein kinase subunit gamma-1/0.474
2zu9GDPMannosyl-3-phosphoglycerate synthase2.4.1.2170.474
2gesCOKPantothenate kinase2.7.1.330.473
4b2gV1NUncharacterized protein/0.473
2ejzSAHDiphthine synthase/0.472
2qo4CHDFatty acid-binding protein 10-A, liver basic/0.472
3ituIBMcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.472
4geb0LDKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.472
4u0zAPCAdenosine monophosphate-protein transferase FICD2.7.7.n10.472
2e07SAHDiphthine synthase/0.471
2y8qADP5'-AMP-activated protein kinase subunit gamma-1/0.471
3kxoKXOHematopoietic prostaglandin D synthase/0.471
3pe2E1BCasein kinase II subunit alpha2.7.11.10.471
4fvz4KJNitric oxide synthase, brain1.14.13.390.471
2pr2DG1Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.470
3gueUPGUTP-glucose-1-phosphate uridylyltransferase 2, putative/0.470
3zecANPAdenosine monophosphate-protein transferase SoFic2.7.7.n10.470
4cdmFO1Deoxyribodipyrimidine photolyase/0.470
1bwsNDPGDP-L-fucose synthase/0.469
1rc4DDFDihydrofolate reductase1.5.1.30.469
1touB1VFatty acid-binding protein, adipocyte/0.469
3q43D66M1 family aminopeptidase3.4.110.469
4cjwCBJIntegrase/0.469
4ehzJAKTyrosine-protein kinase JAK1/0.469
2v7a627Tyrosine-protein kinase ABL12.7.10.20.468
3p3c3P3UDP-3-O-acyl-N-acetylglucosamine deacetylase/0.468
1fxsNAPGDP-L-fucose synthase/0.467
1nquRDL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.467
1xddAAYIntegrin alpha-L/0.467
2bxoOPBSerum albumin/0.467
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.467
2g226IGRenin3.4.23.150.466
4g73NAIRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.466
4u0sADPAdenosine monophosphate-protein transferase FICD2.7.7.n10.466
1di8DTQCyclin-dependent kinase 22.7.11.220.465
1vbiNADMalate/L-lactate dehydrogenase family protein/0.465
1vbmYSATyrosine--tRNA ligase6.1.1.10.465
1yqzCOACoenzyme A disulfide reductase/0.465
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.465
2vesGVRUDP-3-O-acyl-N-acetylglucosamine deacetylase/0.465
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.465
4euxHW1Nitric oxide synthase, brain1.14.13.390.465
4nieNBHNuclear receptor ROR-gamma/0.465
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.464
2r0pK2CPutative FAD-monooxygenase/0.464
2z9dFMNFMN-dependent NADH-azoreductase/0.464
3jynNDPQuinone oxidoreductase/0.464
3of4FMNNitroreductase/0.464
1e8zSTUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.463
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.463
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.463
3sfeFADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/0.463
4a83DXCMajor pollen allergen Bet v 1-A/0.463
4dieC5PCytidylate kinase/0.463
4ipw1G7Mycocyclosin synthase1.14.21.90.463
5dozNDPJamJ/0.463
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.462
3vtbTKAVitamin D3 receptor/0.462
4b4w9L9Bifunctional protein FolD/0.462
4eqwCOACoenzyme A disulfide reductase/0.462
4u07ATPAdenosine monophosphate-protein transferase FICD2.7.7.n10.462
1tysTMPThymidylate synthase/0.461
2jb4A14Isopenicillin N synthase1.21.3.10.461
2w71L23Biotin carboxylase6.3.4.140.461
3ec7NADInositol 2-dehydrogenase/0.461
3vt7VDXVitamin D3 receptor/0.461
4a2aATPCell division protein FtsA/0.461
4ge40KEKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.461
4jubTPPBenzoylformate decarboxylase4.1.1.70.461
4nxwADPMitochondrial dynamics protein MID51/0.461
4yaw2AMNADPH--cytochrome P450 reductase/0.461
1m67BOAGlycerol-3-phosphate dehydrogenase [NAD(+)], glycosomal1.1.1.80.460
1olmVTQSEC14-like protein 2/0.460
1xuzMMNCapsule biosynthesis protein/0.460
1zdwFLVPrenyltransferase/0.460
2cmjNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.460
2w2lNADD-mandelate dehydrogenase/0.460
3b70NAPEnoyl reductase LovC10.460
3oqkS52Renin3.4.23.150.460
3qi2GDPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.460
3zoiM2WIsopenicillin N synthase1.21.3.10.460
4x7wMVIMycinamicin III 3''-O-methyltransferase2.1.1.2370.460
1juvNDPDihydrofolate reductase1.5.1.30.459
1rx0FADIsobutyryl-CoA dehydrogenase, mitochondrial1.3.990.459
2c1zKMPAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.459
2cjfRP43-dehydroquinate dehydratase4.2.1.100.459
2zl9VDAVitamin D3 receptor/0.459
3enkUPGUDP-glucose 4-epimerase/0.459
3tnlNADShikimate dehydrogenase (NADP(+))/0.459
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.459
4dyn0MRNucleoprotein/0.459
4eqsCOACoenzyme A disulfide reductase/0.459
4wudANPDNA gyrase subunit B/0.459
1in5ADPHolliday junction ATP-dependent DNA helicase RuvB/0.458
1z4uPH9Polyprotein/0.458
2ph5NADHomospermidine synthase/0.458
2wwjY28Lysine-specific demethylase 4A/0.458
4a322CDGlycylpeptide N-tetradecanoyltransferase/0.458
4g1z0VPVitamin D3 receptor A/0.458
4jxrACOAcetyltransferase/0.458
4u8iFDAUDP-galactopyranose mutase/0.458
5bp9SAHPutative methyltransferase protein/0.458
5bylGCPBifunctional AAC/APH2.3.10.458
1dfoFFOSerine hydroxymethyltransferase2.1.2.10.457
1fdtESTEstradiol 17-beta-dehydrogenase 11.1.1.620.457
1jdzFMBPurine nucleoside phosphorylase/0.457
1o04NADAldehyde dehydrogenase, mitochondrial1.2.1.30.457
1o8cNDPProbable acrylyl-CoA reductase AcuI1.3.1.840.457
3cgdCOACoenzyme A disulfide reductase/0.457
3pxyJWSCyclin-dependent kinase 22.7.11.220.457
3rbqGLY_ALA_GLY_DAOProtein unc-119 homolog A/0.457
3up0D7SaceDAF-12/0.457
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.457
4fhj0TZPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
4hw319GInduced myeloid leukemia cell differentiation protein Mcl-1/0.457
4jq3NAPAldo-keto reductase family 1 member C2/0.457
4jqh1MFAlr2278 protein/0.457
4tuvCPZCytochrome P450 1191.140.457
5droZH2UDP-3-O-acyl-N-acetylglucosamine deacetylase/0.457
1j7uANPAminoglycoside 3'-phosphotransferase2.7.1.950.456
2bf7HBIPteridine reductase 11.5.1.330.456
2pb4SAHDiphthine synthase/0.456
2pj4414Carboxypeptidase B/0.456
2y60M8FIsopenicillin N synthase1.21.3.10.456
2y8lADP5'-AMP-activated protein kinase subunit gamma-1/0.456
3vri1KXHLA class I histocompatibility antigen, B-57 alpha chain/0.456
4da8BG2Purine nucleoside phosphorylase DeoD-type2.4.2.10.456
4kzoNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.456
1bpwNADBetaine aldehyde dehydrogenase1.2.1.80.455
1nzdUPGDNA beta-glucosyltransferase/0.455
1wp4NDP3-hydroxyisobutyrate dehydrogenase/0.455
2bf4FADNADPH--cytochrome P450 reductase/0.455
2dsgSAHDiphthine synthase/0.455
2el0SAHDiphthine synthase/0.455
2pciSAHDiphthine synthase/0.455
2vwqNAPGlucose 1-dehydrogenase/0.455
2zsaADPPantothenate kinase2.7.1.330.455
3gc9B45Mitogen-activated protein kinase 112.7.11.240.455
3i0pNADMalate dehydrogenase, putative/0.455
3tm5SFGUncharacterized protein/0.455
3uyk0CXProbable NDP-rhamnosyltransferase/0.455
4ddl0JQcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.455
4eakATP5'-AMP-activated protein kinase subunit gamma-1/0.455
4obwSAM2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial/0.455
4umxNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.455
5dldUD1UDP-N-Acetylglucosamine 2-epimerase/0.455
1aquESTEstrogen sulfotransferase, testis isoform2.8.2.40.454
1p0hACOMycothiol acetyltransferase2.3.1.1890.454
1u3cFADCryptochrome-1/0.454
1uaeUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.454
2f6rACOBifunctional coenzyme A synthase/0.454
2mm3CHOGastrotropin/0.454
2owfSAHDiphthine synthase/0.454
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.454
3g1rFIT3-oxo-5-beta-steroid 4-dehydrogenase/0.454
3giyFMN(S)-mandelate dehydrogenase1.1.99.310.454
3wv9FEGHmd co-occurring protein HcgE/0.454
4g6hNAIRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.454
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.454
4xoqF42Coenzyme F420:L-glutamate ligase/0.454
5c3jFADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/0.454
5cyoGDPSeptin-9/0.454
1gky5GPGuanylate kinase2.7.4.80.453
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.453
1r6uTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.453
2eglSAHDiphthine synthase/0.453
2i0y5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.453
2vbdV10Isopenicillin N synthase1.21.3.10.453
2vbpVB1Isopenicillin N synthase1.21.3.10.453
2watCOAFatty acid synthase subunit alpha2.3.1.860.453
3o26NDPSalutaridine reductase/0.453
4at0FADPossible succinate dehydrogenase/0.453
4bb3KKAIsopenicillin N synthase1.21.3.10.453
4yqfGDPSeptin-9/0.453
1egdFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.452
1kbjFMNCytochrome b2, mitochondrial1.1.2.30.452
1mczRMNBenzoylformate decarboxylase4.1.1.70.452
1rf7DHFDihydrofolate reductase1.5.1.30.452
1u2gAPRNAD(P) transhydrogenase subunit alpha part 11.6.1.20.452
2gjlFMNNitronate monooxygenase1.13.12.160.452
2hr8SAHDiphthine synthase/0.452
2nnqT4BFatty acid-binding protein, adipocyte/0.452
2rc3NADCBS domain/0.452
2v58LZJBiotin carboxylase6.3.4.140.452
3bxxQUEDihydroflavonol 4-reductase1.1.1.2190.452
3inmNDPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.452
3o57ZG2cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.452
3s1aATPCircadian clock protein kinase KaiC2.7.11.10.452
3vthAPCCarbamoyltransferase/0.452
4b4vL34Bifunctional protein FolD/0.452
4b6s2HN3-dehydroquinate dehydratase4.2.1.100.452
4dpy2P0Mevalonate diphosphate decarboxylase/0.452
4iah1DXAlr2278 protein/0.452
4jtqNAPAldo-keto reductase family 1 member C2/0.452
4jufTPPBenzoylformate decarboxylase4.1.1.70.452
4l4xNDPAmphI/0.452
4nu5NADPhosphonate dehydrogenase1.20.1.10.452
5iu4ZMAAdenosine receptor A2a/0.452
4xnw2IDP2Y purinoceptor 1/0.452
1dgfNDPCatalase1.11.1.60.451
1eyyNAPNADP-dependent fatty aldehyde dehydrogenase1.2.1.40.451
1hb1OCVIsopenicillin N synthase1.21.3.10.451
1s3zCOAAminoglycoside N(6')-acetyltransferase type 1/0.451
1z0aGDPRas-related protein Rab-2A/0.451
2ed3SAHDiphthine synthase/0.451
2ejkSAHDiphthine synthase/0.451
3cgeCOACoenzyme A disulfide reductase/0.451
3fhxPLPPyridoxal kinase2.7.1.350.451
3uleC69Actin-related protein 3/0.451
4gapNADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.451
4k9nTZDBenzoylformate decarboxylase4.1.1.70.451
4nu6NADPhosphonate dehydrogenase1.20.1.10.451
4nxvGDPMitochondrial dynamics protein MID51/0.451
4twnB96Ephrin type-A receptor 32.7.10.10.451
5dqrFAD7-hydroxymethyl chlorophyll a reductase, chloroplastic1.17.7.20.451
1hk5T44Serum albumin/0.450
1kt6RTLRetinol-binding protein 4/0.450
1umlFR4Adenosine deaminase3.5.4.40.450
2dshSAHDiphthine synthase/0.450
2en5SAHDiphthine synthase/0.450
4e5kNADPhosphonate dehydrogenase1.20.1.10.450
4eetFMNPhototropin-22.7.11.10.450
4jlk1NODeoxycytidine kinase2.7.1.740.450
4k0zMZMCarbonic anhydrase 24.2.1.10.450
4ockANPN-acetylhexosamine 1-kinase2.7.1.1620.450
4ph9IBPProstaglandin G/H synthase 21.14.99.10.450
4zs2FLUAlpha-ketoglutarate-dependent dioxygenase FTO/0.450
1o9bNAIQuinate/shikimate dehydrogenase/0.449
1qoqIGPTryptophan synthase alpha chain/0.449
1wc5APCAdenylate cyclase/0.449
1yzqGNPRas-related protein Rab-6A/0.449
2e08SAHDiphthine synthase/0.449
2ed5SAHDiphthine synthase/0.449
2rh9IGPTryptophan synthase alpha chain/0.449
2uxoTACHTH-type transcriptional regulator TtgR/0.449
2wjoQUDBeta-secretase 13.4.23.460.449
2zdyADP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial2.7.11.20.449
3c212BADNA integrity scanning protein DisA/0.449
3d8vUD1Bifunctional protein GlmU/0.449
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.449
3hy310F5-formyltetrahydrofolate cyclo-ligase6.3.3.20.449
3tdaPN0Cytochrome P450 2D6/0.449
3w8rACPUridine kinase/0.449
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
4bftZVTPantothenate kinase2.7.1.330.449
4bfvZVVPantothenate kinase2.7.1.330.449
4bgiI4IEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.449
4dpwAGSMevalonate diphosphate decarboxylase/0.449
4egbNADdTDP-glucose 4,6-dehydratase/0.449
4ge90L0Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.449
4h6rFDAProline dehydrogenase/0.449
4lxhC1EAlpha/beta hydrolase fold/0.449
4rvuNDPProbable quinone reductase Qor (NADPH:quinone reductase) (Zeta-crystallin homolog protein)/0.449
1e1qADPATP synthase subunit beta, mitochondrial3.6.3.140.448
1q19SSCCarbapenam-3-carboxylate synthase6.3.3.60.448
1u1f183Uridine phosphorylase2.4.2.30.448
1uzwCDHIsopenicillin N synthase1.21.3.10.448
1wvgCXYCDP-glucose 4,6-dehydratase4.2.1.450.448
1zarADPRIO-type serine/threonine-protein kinase Rio22.7.11.10.448
2bjhFERFeruloyl esterase A3.1.1.730.448
2e0aANP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial2.7.11.20.448
2e4nSAHDiphthine synthase/0.448
2e77FMNLactate oxidase/0.448
2h447CAcGMP-specific 3',5'-cyclic phosphodiesterase/0.448
2pb6SAHDiphthine synthase/0.448
2pcmSAHDiphthine synthase/0.448
2z7hGG3Geranylgeranyl pyrophosphate synthase/0.448
2zlcVDXVitamin D3 receptor/0.448
3bloQEIQueuine tRNA-ribosyltransferase2.4.2.290.448
3btsNADGalactose/lactose metabolism regulatory protein GAL80/0.448
3ixp834Ecdysone receptor/0.448
3lpkZ76Beta-secretase 13.4.23.460.448
4bfuZVUPantothenate kinase2.7.1.330.448
4dz5NAPAldo-keto reductase family 1 member C3/0.448
4fehFADDecaprenylphosphoryl-beta-D-ribose oxidase/0.448
4g8jTHMUridine phosphorylase/0.448
4i1nFOLDihydrofolate reductase1.5.1.30.448
4mwzSAMPhosphoethanolamine N-methyltransferase, putative/0.448
4ocpADPN-acetylhexosamine 1-kinase2.7.1.1620.448
4xfjANPArgininosuccinate synthase/0.448
1menGARTrifunctional purine biosynthetic protein adenosine-32.1.2.20.447
1s19MC9Vitamin D3 receptor/0.447
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.447
2ev9NAPShikimate dehydrogenase (NADP(+))/0.447
2hs0ATPPhosphoribosylformylglycinamidine synthase subunit PurL/0.447
2nliFMNLactate oxidase/0.447
2rg5279Mitogen-activated protein kinase 14/0.447
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
2x8hFADThioredoxin glutathione reductase/0.447
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.447
3fznD7KBenzoylformate decarboxylase4.1.1.70.447
3h3cP1EProtein-tyrosine kinase 2-beta2.7.10.20.447
3ts1TYATyrosine--tRNA ligase6.1.1.10.447
3vhxGTPADP-ribosylation factor 6/0.447
4f6s0SQCyclin-dependent kinase 82.7.11.220.447
4hj6FMNLOV protein/0.447
4ia7BIVVitamin D3 receptor A/0.447
4l9q9TPSerum albumin/0.447
4relKMPGlycosyltransferase/0.447
4rxsTTPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.447
4u9zCOAAlpha-tubulin N-acetyltransferase 1/0.447
4zwpM44Xaa-Pro dipeptidase3.4.13.90.447
7catNDPCatalase1.11.1.60.447
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.446
1kruIPTGalactoside O-acetyltransferase2.3.1.180.446
1mczTDPBenzoylformate decarboxylase4.1.1.70.446
1oc1ASVIsopenicillin N synthase1.21.3.10.446
1txtCAAHMG-CoA synthase/0.446
2dxwSAHDiphthine synthase/0.446
2e8qSAHDiphthine synthase/0.446
2hb8MVDVitamin D3 receptor/0.446
2iviACWIsopenicillin N synthase1.21.3.10.446
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.446
2ouyCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.446
3akm11DFatty acid-binding protein, intestinal/0.446
3b1dPLSBetaC-S lyase/0.446
3junAJDPhenazine biosynthesis protein A/B/0.446
3qm4PN0Cytochrome P450 2D6/0.446
3sn7540cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.446
3upkUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.446
3wycNAPMeso-diaminopimelate D-dehydrogenase1.4.1.160.446
4eqrCOACoenzyme A disulfide reductase/0.446
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.446
4lzwTHMUridine phosphorylase/0.446
1itzTPPTransketolase, chloroplastic2.2.1.10.445
1j49NADD-lactate dehydrogenase1.1.1.280.445
2bu9HFVIsopenicillin N synthase1.21.3.10.445
2cmvNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.445
2du8FADD-amino-acid oxidase1.4.3.30.445
2e17SAHDiphthine synthase/0.445
2ek3SAHDiphthine synthase/0.445
2eniSAHDiphthine synthase/0.445
2harOCCVitamin D3 receptor/0.445
2hc4VDXVitamin D3 receptor A/0.445
2ydbNAP2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.445
3ac1KZITyrosine-protein kinase Lck2.7.10.20.445
3csoXNIGenome polyprotein2.7.7.480.445
3nmnPYVAbscisic acid receptor PYL1/0.445
3ntgD72Prostaglandin G/H synthase 21.14.99.10.445
3owj1ELCasein kinase II subunit alpha2.7.11.10.445
3rtnRTNBeta-secretase 13.4.23.460.445
3w2fNADNADH-cytochrome b5 reductase 31.6.2.20.445
4dyp0MSNucleoprotein/0.445
4fcd0T6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.445
4gl4NAIAlcohol dehydrogenase class-3/0.445
4hvb19PPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
4l17DNQGlutamate receptor 2/0.445
4ng2OHNTranscriptional activator protein LasR/0.445
5k2cZMAAdenosine receptor A2a/0.445
1akcPPEAspartate aminotransferase, mitochondrial2.6.1.10.444
1b48HAGGlutathione S-transferase A42.5.1.180.444
1bk0ACVIsopenicillin N synthase1.21.3.10.444
1bxrANPCarbamoyl-phosphate synthase large chain/0.444
1fcbFMNCytochrome b2, mitochondrial1.1.2.30.444
1fduESTEstradiol 17-beta-dehydrogenase 11.1.1.620.444
1jjeBYSBeta-lactamase/0.444
1pjkANPCasein kinase II subunit alpha2.7.11.10.444
1swtBTNStreptavidin/0.444
1t9gFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.444
2ch6ADPN-acetyl-D-glucosamine kinase2.7.1.590.444
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.444
2oyeIM8Prostaglandin G/H synthase 11.14.99.10.444
2p6kSAHDiphthine synthase/0.444
2vczVC3Hematopoietic prostaglandin D synthase/0.444
3a1cACPProbable copper-exporting P-type ATPase A3.6.3.540.444
3br3ETHTH-type transcriptional regulator QacR/0.444
3c3xNAPEugenol synthase 11.1.1.3180.444
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
3gu83GUDeath-associated protein kinase 12.7.11.10.444
3h3sH15Collagen type IV alpha-3-binding protein/0.444
3lu8IQXSerum albumin/0.444
3qtuX44Cyclin-dependent kinase 22.7.11.220.444
3r83Z14Cyclin-dependent kinase 22.7.11.220.444
4at2ASDPossible succinate dehydrogenase/0.444
4dbzNDPPutative ketoacyl reductase1.3.10.444
4g8zTOPDihydrofolate reductase1.5.1.30.444
4jlm1NNDeoxycytidine kinase2.7.1.740.444
4kcfAKMFAD-dependent oxidoreductase/0.444
4o701QKBromodomain-containing protein 4/0.444
4xba5GPAprataxin-like protein30.444
4y9lFADAcyl-CoA dehydrogenase family member 11/0.444
5hwrCOAHydroxymethylglutaryl-CoA synthase/0.444
1a8rGTPGTP cyclohydrolase 13.5.4.160.443
1g0nNDPTetrahydroxynaphthalene reductase1.1.1.2520.443
1orrCDPCDP-paratose 2-epimerase/0.443
1q0zAKAAclacinomycin methylesterase RdmC3.1.1.950.443
1qjfACSIsopenicillin N synthase1.21.3.10.443
1z1fSTLResveratrol synthase/0.443
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.443
2h2aDNDProbable nicotinate-nucleotide adenylyltransferase/0.443
2ix5FADAcyl-coenzyme A oxidase 4, peroxisomal1.3.3.60.443
2j6xFMNLactate oxidase/0.443
2o23NAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.443
2oatPFMOrnithine aminotransferase, mitochondrial2.6.1.130.443
2qo6CHDFatty acid-binding protein 10-A, liver basic/0.443
2v3aFADRubredoxin-NAD(+) reductase1.18.1.10.443
2vouFAD2,6-dihydroxypyridine 3-monooxygenase1.14.13.100.443
2wksCB63-dehydroquinate dehydratase4.2.1.100.443
2wufKEM4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.443
2xysSY9Soluble acetylcholine receptor/0.443
3d8bADPFidgetin-like protein 13.6.40.443
3hyoADPPyridoxal kinase/0.443
3jypNADQuinate/shikimate dehydrogenase (NAD(+))/0.443
3lpiZ74Beta-secretase 13.4.23.460.443
3o56ZG1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.443
3oibFDAPutative acyl-CoA dehydrogenase/0.443
3pcrGTPADP-ribosylation factor 6/0.443
3q8hAO92-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase/0.443
3v0p4GWHisto-blood group ABO system transferase/0.443
4da6GA2Purine nucleoside phosphorylase DeoD-type2.4.2.10.443
4fqsLYAThymidylate synthase ThyA/0.443
4hjfC2EGGDEF family protein/0.443
4hxyNDPPlm1/0.443
4is3NAD3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 21.17.98.10.443
4k9oTPPBenzoylformate decarboxylase4.1.1.70.443
4lsl1YQGag-Pol polyprotein2.7.7.490.443
4mxeACON-acetyltransferase ESCO12.3.10.443
4prvADPDNA gyrase subunit B/0.443
4ubvCOASteroid 3-ketoacyl-CoA thiolase/0.443
4y93746Tyrosine-protein kinase/0.443
5br7FADUDP-galactopyranose mutase/0.443
5fm7ADPRuvB-like helicase/0.443
1ascNPLAspartate aminotransferase2.6.1.10.442
1e8xATPPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.442
1kqnNADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.442
1o01NADAldehyde dehydrogenase, mitochondrial1.2.1.30.442
2c4jGSOGlutathione S-transferase Mu 22.5.1.180.442
2c59NADGDP-mannose 3,5-epimerase5.1.3.180.442
2dv7SAHDiphthine synthase/0.442
2f98NGVAklanonic acid methyl ester cyclase AcmA5.5.1.230.442
2gblATPCircadian clock protein kinase KaiC2.7.11.10.442
2gmhFADElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial1.5.5.10.442
2ntvP1HEnoyl-[acyl-carrier-protein] reductase [NADH]/0.442
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.442
2p5cSAHDiphthine synthase/0.442
2v6gNAP3-oxo-Delta(4,5)-steroid 5-beta-reductase/0.442
3aezGDPPantothenate kinase2.7.1.330.442
3dvlATPCircadian clock protein kinase KaiC2.7.11.10.442
3gpcCOAAcyl-coenzyme A synthetase ACSM2A, mitochondrial6.2.1.20.442
3gwfFADCyclohexanone monooxygenase/0.442
3iakEV1cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.442
3m34TPPTransketolase/0.442
3p2oNADBifunctional protein FolD/0.442
3pm1ETHTH-type transcriptional regulator QacR/0.442
3tjzGNPADP-ribosylation factor 1/0.442
3vt9YI4Vitamin D3 receptor/0.442
3w32W32Epidermal growth factor receptor2.7.10.10.442
3w78CBDFMN-dependent NADH-azoreductase/0.442
4i6aHMG3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.442
4jlj1NMDeoxycytidine kinase2.7.1.740.442
4oztP1AEcdysone receptor, putative/0.442
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.442
5iu86DZAdenosine receptor A2a/0.442
1blzACVIsopenicillin N synthase1.21.3.10.441
1cbqRE9Cellular retinoic acid-binding protein 2/0.441
1ejiTHFSerine hydroxymethyltransferase, cytosolic/0.441
1i5bANPChemotaxis protein CheA2.7.13.30.441
1i75NOJCyclomaltodextrin glucanotransferase2.4.1.190.441
1oj4CDM4-diphosphocytidyl-2-C-methyl-D-erythritol kinase2.7.1.1480.441
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.441
1ro98BRcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.441
1sojIBMcGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.441
1xdpATPPolyphosphate kinase/0.441
1zprCB3Thymidylate synthase/0.441
2daaDCSD-alanine aminotransferase2.6.1.210.441
2dekSAHDiphthine synthase/0.441
2dxvSAHDiphthine synthase/0.441
2e1zB4PPropionate kinase/0.441
2e8sSAHDiphthine synthase/0.441
2e95B75Geranylgeranyl pyrophosphate synthase/0.441
2nnlNAPDihydroflavonol 4-reductase1.1.1.2190.441
2o1xTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.441
3cgcCOACoenzyme A disulfide reductase/0.441
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
3gytDL4Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.441
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
3uwlFOZThymidylate synthase/0.441
3v4tUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.441
3w0gW07Vitamin D3 receptor/0.441
4g090VDHistidinol dehydrogenase/0.441
4gyzD5MTyrosyl-DNA phosphodiesterase 23.1.40.441
4i02CMPcAMP-activated global transcriptional regulator CRP/0.441
4iae1DXAlr2278 protein/0.441
4kx6FADFumarate reductase flavoprotein subunit1.3.5.40.441
4nfhPFBAlcohol dehydrogenase E chain1.1.1.10.441
4r1fADPDNA topoisomerase 2-alpha5.99.1.30.441
5di3GNPADP-ribosylation factor-like protein 3/0.441
1adfTADAlcohol dehydrogenase E chain1.1.1.10.440
1bsvNDPGDP-L-fucose synthase/0.440
1enoNADEnoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic1.3.1.90.440
1fxfMJIPhospholipase A2, major isoenzyme3.1.1.40.440
1joaFADNADH peroxidase1.11.1.10.440
1tsxUMPThymidylate synthase/0.440
1u1cBAUUridine phosphorylase2.4.2.30.440
1uy9PU6Heat shock protein HSP 90-alpha/0.440
1ysx4EBSerum albumin/0.440
2bt4CA23-dehydroquinate dehydratase4.2.1.100.440
2c27ACOMycothiol acetyltransferase2.3.1.1890.440
2onmADPAldehyde dehydrogenase, mitochondrial1.2.1.30.440
2p5fSAHDiphthine synthase/0.440
2w6nOA2Biotin carboxylase6.3.4.140.440
3dd125DGlycogen phosphorylase, liver form2.4.1.10.440
3dds26BGlycogen phosphorylase, liver form2.4.1.10.440
3hmvHBTcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.440
3m13FADMonomeric sarcosine oxidase1.5.3.10.440
3otwCOAPhosphopantetheine adenylyltransferase/0.440
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.440
3ske054Genome polyprotein2.7.7.480.440
3uhmRFNUDP-3-O-acyl-N-acetylglucosamine deacetylase/0.440
3uptTPPTransketolase/0.440
3w9rA8SAbscisic acid receptor PYL9/0.440
4a2zVIQGlycylpeptide N-tetradecanoyltransferase/0.440
4awkCI1Polymerase acidic protein/0.440
4cf1IY7Integrase/0.440
4dc0NDPPutative ketoacyl reductase1.3.10.440
4jtrIZPAldo-keto reductase family 1 member C2/0.440
4llkMEWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.440
4ng5PFBAlcohol dehydrogenase E chain1.1.1.10.440
4pt0NADAldehyde dehydrogenase/0.440
4djhJDCKappa-type opioid receptor/0.440