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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3w2mZRODihydroorotate dehydrogenase (fumarate)1.3.98.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
3w2mZRODihydroorotate dehydrogenase (fumarate)1.3.98.11.000
3w3oROEDihydroorotate dehydrogenase (fumarate)1.3.98.10.637
3w2nRODDihydroorotate dehydrogenase (fumarate)1.3.98.10.626
3w1tWRODihydroorotate dehydrogenase (fumarate)1.3.98.10.602
3w2uROUDihydroorotate dehydrogenase (fumarate)1.3.98.10.541
3w1xXRODihydroorotate dehydrogenase (fumarate)1.3.98.10.540
3w2jQRODihydroorotate dehydrogenase (fumarate)1.3.98.10.527
3f03FMNPentaerythritol tetranitrate reductase/0.524
3w1rMRODihydroorotate dehydrogenase (fumarate)1.3.98.10.523
3w1qYRODihydroorotate dehydrogenase (fumarate)1.3.98.10.514
2dftADPShikimate kinase2.7.1.710.511
4eagATP5'-AMP-activated protein kinase subunit gamma-1/0.510
1h63FMNPentaerythritol tetranitrate reductase/0.501
3h06VBPGlutamate receptor 2/0.501
1h51FMNPentaerythritol tetranitrate reductase/0.498
4loi1YCStimulator of interferon genes protein/0.498
3atzFMNProstaglandin F2a synthase/0.492
3p62FMNPentaerythritol tetranitrate reductase/0.487
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.487
1icpFMN12-oxophytodienoate reductase 11.3.1.420.485
4hmz18TdTDP-4-dehydro-6-deoxyglucose 3-epimerase5.1.3.270.485
1ez4NADL-lactate dehydrogenase1.1.1.270.484
1h50FMNPentaerythritol tetranitrate reductase/0.484
1xe55FEPlasmepsin-23.4.23.390.484
2il2LIXRenin3.4.23.150.483
4e2dFMNDehydrogenase/0.483
3p82FMNPentaerythritol tetranitrate reductase/0.482
1bwsNDPGDP-L-fucose synthase/0.481
3kb1ADPIron-sulfur cluster carrier protein/0.481
4g74FADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.481
3f1kNAPUncharacterized oxidoreductase YciK10.480
3mgdACOPredicted acetyltransferase/0.480
1vyrFMNPentaerythritol tetranitrate reductase/0.479
4g9kFADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.479
4iaxLIZNeutrophil gelatinase-associated lipocalin/0.479
4jicFMNGTN Reductase/0.479
1bwlFMNNADPH dehydrogenase 11.6.99.10.478
1nzdUPGDNA beta-glucosyltransferase/0.478
1xe65FPPlasmepsin-23.4.23.390.478
2zuiCAMCamphor 5-monooxygenase1.14.15.10.477
3fwgCAMCamphor 5-monooxygenase1.14.15.10.477
3p74FMNPentaerythritol tetranitrate reductase/0.477
3o03NAPDehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase)/0.476
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.475
1c9k5GPBifunctional adenosylcobalamin biosynthesis protein CobU/0.474
1t87CAMCamphor 5-monooxygenase1.14.15.10.474
2ad5ADPCTP synthase/0.474
2hfuMEVMevalonate kinase/0.474
2o4cNADErythronate-4-phosphate dehydrogenase/0.474
3qt62P0Mevalonate diphosphate decarboxylase/0.474
3tjzGNPADP-ribosylation factor 1/0.474
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.474
1x1bSAHC-20 methyltransferase/0.473
1gcoNADGlucose 1-dehydrogenase1.1.1.470.472
3s1dZIRCytokinin dehydrogenase 11.5.99.120.472
3u9eCOALmo1369 protein/0.472
4nmdFDABifunctional protein PutA/0.472
3cisATPUniversal stress protein Rv2623/0.471
3kjiADPCO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC/0.471
1a5bIGPTryptophan synthase alpha chain/0.470
2zsaADPPantothenate kinase2.7.1.330.470
4eywL0RCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.470
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.470
2abbFMNPentaerythritol tetranitrate reductase/0.469
1nzfUPGDNA beta-glucosyltransferase/0.468
1x1aSAMC-20 methyltransferase/0.468
2c27ACOMycothiol acetyltransferase2.3.1.1890.468
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.468
2hs6FMN12-oxophytodienoate reductase 31.3.1.420.468
2hs8FMN12-oxophytodienoate reductase 31.3.1.420.468
2j5xGSPADP-ribosylation factor 6/0.468
2q46NAPUncharacterized protein At5g02240/0.468
3enkUPGUDP-glucose 4-epimerase/0.468
3p67FMNPentaerythritol tetranitrate reductase/0.468
1h7wFMNDihydropyrimidine dehydrogenase [NADP(+)]1.3.1.20.467
4jc51K5Stimulator of interferon genes protein/0.467
1ikgREXD-alanyl-D-alanine carboxypeptidase3.4.16.40.466
2j08IRFDeoxyribodipyrimidine photo-lyase4.1.99.30.466
3imgBZ2Pantothenate synthetase6.3.2.10.466
4hbgNDP3-oxoacyl-[acyl-carrier-protein] reductase1.1.1.1000.466
4q72FADBifunctional protein PutA/0.466
1hdgNADGlyceraldehyde-3-phosphate dehydrogenase/0.465
1kp3ATPArgininosuccinate synthase6.3.4.50.465
1rf7DHFDihydrofolate reductase1.5.1.30.465
2b37NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.465
3gqvNAPEnoyl reductase LovC10.465
3tr05GPGuanylate kinase/0.465
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.464
4h8aNAIUreidoglycolate dehydrogenase (NAD(+))1.1.1.3500.464
4i9n1E5L-lactate dehydrogenase A chain1.1.1.270.464
4itmATPTetraacyldisaccharide 4'-kinase/0.464
4kbyC2EStimulator of interferon genes protein/0.464
1h74ADPHomoserine kinase2.7.1.390.463
2a5kAZPReplicase polyprotein 1ab3.4.220.463
3gfbNADL-threonine 3-dehydrogenase/0.463
3gwfNAPCyclohexanone monooxygenase/0.463
3p8jFMNPentaerythritol tetranitrate reductase/0.463
4rvdSAMD-mycarose 3-C-methyltransferase/0.463
4xguADPPutative pachytene checkpoint protein 2/0.463
1h73ANPHomoserine kinase2.7.1.390.462
2gmhFADElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial1.5.5.10.462
2gv8NDPThiol-specific monooxygenase1.14.130.462
2q1wNADPutative nucleotide sugar epimerase/ dehydratase/0.462
3hgoFMN12-oxophytodienoate reductase 31.3.1.420.462
3lqfNADGalactitol dehydrogenase/0.462
4a862ANMajor pollen allergen Bet v 1-A/0.462
4hmsFMNPhenazine biosynthesis protein PhzG1.40.462
4m55NADUDP-glucuronic acid decarboxylase 14.1.1.350.462
4mkhAP5Adenylate kinase/0.462
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.462
4uwmFMN3,6-diketocamphane 1,6 monooxygenase1.14.130.462
5ftfADPTPR domain protein/0.462
1yrdCAMCamphor 5-monooxygenase1.14.15.10.461
2a94AP0L-lactate dehydrogenase1.1.1.270.461
2ft9CHDFatty acid-binding protein 2, liver/0.461
2gjlFMNNitronate monooxygenase1.13.12.160.461
2he5NDPAldo-keto reductase family 1 member C211.1.10.461
3gkaFMNN-ethylmaleimide reductase/0.461
4bqpNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.461
4l7f1V5Mitogen-activated protein kinase 82.7.11.240.461
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.461
4yj2GTPTubulin alpha-1B chain/0.461
1fxsNAPGDP-L-fucose synthase/0.460
1jueFMNDihydroorotate dehydrogenase A (fumarate)1.3.98.10.460
1tqf32PBeta-secretase 13.4.23.460.460
2eklNADD-3-phosphoglycerate dehydrogenase/0.460
2jahNDPClavaldehyde dehydrogenase/0.460
2q85973UDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.460
3w6hAZMCarbonic anhydrase 14.2.1.10.460
4q71FADBifunctional protein PutA/0.460
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.459
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.459
1icqFMN12-oxophytodienoate reductase 11.3.1.420.459
1udaUFGUDP-glucose 4-epimerase5.1.3.20.459
2iibC5PAlpha-2,3/2,6-sialyltransferase/sialidase/0.459
2qs3UBEGlutamate receptor ionotropic, kainate 1/0.459
2rh9IGPTryptophan synthase alpha chain/0.459
3il1B5DGlutamate receptor 2/0.459
3wrmCAMCamphor 5-monooxygenase1.14.15.10.459
4lol1YEStimulator of interferon genes protein/0.459
4tmbFMNOld yellow enzyme/0.459
4yr9NADL-threonine 3-dehydrogenase, mitochondrial1.1.1.1030.459
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.458
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.458
2cy0NAPShikimate dehydrogenase (NADP(+))/0.458
2i3gNAPN-acetyl-gamma-glutamyl-phosphate reductase1.2.1.380.458
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.458
2i51FMNPyridoxamine 5'-phosphate oxidase-related, FMN-binding/0.458
3axkNDPRibulose bisphosphate carboxylase large chain4.1.1.390.458
3ijoB4DGlutamate receptor 2/0.458
3ru9NADUDP-N-acetylglucosamine 4-epimerase/0.458
3w8eNAD3-hydroxybutyrate dehydrogenase/0.458
3zhbNAPPutative dehydrogenase/0.458
4gdcNDPUDP-galactopyranose mutase/0.458
4ki8ADP60 kDa chaperonin/0.458
4tmcFMNOld yellow enzyme/0.458
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.458
1pjcNADAlanine dehydrogenase/0.457
2g226IGRenin3.4.23.150.457
2ou5FMNPyridoxamine 5'-phosphate oxidase-related FMN-binding protein/0.457
2vcmM11Isopenicillin N synthase1.21.3.10.457
3ag6PAJPantothenate synthetase/0.457
3hl0NADMaleylacetate reductase/0.457
3otwCOAPhosphopantetheine adenylyltransferase/0.457
4bb3KKAIsopenicillin N synthase1.21.3.10.457
4c13UMLUDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase/0.457
4i1iNADMalate dehydrogenase/0.457
4k36SAMAnaerobic sulfatase-maturating enzyme1.8.980.457
4m4922YL-lactate dehydrogenase A chain1.1.1.270.457
4xq6FMNDihydroorotate dehydrogenase (quinone)/0.457
1hkuNADC-terminal-binding protein 11.1.10.456
1nooCAHCamphor 5-monooxygenase1.14.15.10.456
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.456
1o76CAMCamphor 5-monooxygenase1.14.15.10.456
1p31EPUUDP-N-acetylmuramate--L-alanine ligase6.3.2.80.456
1wc4APCAdenylate cyclase/0.456
2cmjNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.456
2qw034Z4-chlorobenzoyl CoA ligase/0.456
3dszLIZNeutrophil gelatinase-associated lipocalin/0.456
3fwfCAMCamphor 5-monooxygenase1.14.15.10.456
3w0nANPHygromycin-B 4-O-kinase2.7.1.1630.456
3w2lVRODihydroorotate dehydrogenase (fumarate)1.3.98.10.456
4k6fNAPPutative Acetoacetyl-CoA reductase/0.456
4qxp1YEStimulator of interferon genes protein/0.456
1ds7FMNOxygen-insensitive NAD(P)H nitroreductase/0.455
1nvtNAPShikimate dehydrogenase (NADP(+))/0.455
1q8uH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.455
1tytFADTrypanothione reductase1.8.1.120.455
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.455
2dfvNADL-threonine 3-dehydrogenase/0.455
2qtcTDKPyruvate dehydrogenase E1 component1.2.4.10.455
3gy0NAPNAD(P)-dependent oxidoreductase/0.455
4bfxZVXPantothenate kinase2.7.1.330.455
4emtC2EStimulator of interferon genes protein/0.455
4eu8COASuccinyl-CoA:acetate CoA-transferase/0.455
4ew3DXZTrifunctional purine biosynthetic protein adenosine-32.1.2.20.455
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.455
4rnvFMNNADPH dehydrogenase 11.6.99.10.455
4v2gITCTetracycline repressor protein class D/0.455
1beuIPLTryptophan synthase alpha chain/0.454
1e7qNAPGDP-L-fucose synthase/0.454
1geeNADGlucose 1-dehydrogenase1.1.1.470.454
1xddAAYIntegrin alpha-L/0.454
2ay3MPPAromatic-amino-acid aminotransferase2.6.1.570.454
2f3rG5PGuanylate kinase2.7.4.80.454
2ztmNADD(-)-3-hydroxybutyrate dehydrogenase/0.454
3bkkKAFAngiotensin-converting enzyme3.2.10.454
3oetNADErythronate-4-phosphate dehydrogenase/0.454
3pqfNADL-lactate dehydrogenase1.1.1.270.454
3q9bB3NAcetylpolyamine amidohydrolase/0.454
3r9uFADThioredoxin reductase/0.454
4kgnSAHtRNA (cytidine(34)-2'-O)-methyltransferase/0.454
4lcjNADC-terminal-binding protein 2/0.454
4zgsNADPutative D-lactate dehydrogenase/0.454
1i5cADPChemotaxis protein CheA2.7.13.30.453
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.453
1rdwLARActin, alpha skeletal muscle/0.453
2a5hSAML-lysine 2,3-aminomutase5.4.3.20.453
2watCOAFatty acid synthase subunit alpha2.3.1.860.453
2yxuATPPyridoxal kinase2.7.1.350.453
3b70NAPEnoyl reductase LovC10.453
3h3t16HCollagen type IV alpha-3-binding protein/0.453
3jypNADQuinate/shikimate dehydrogenase (NAD(+))/0.453
3m2vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.453
3w233RODihydroorotate dehydrogenase (fumarate)1.3.98.10.453
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.453
4eudCOASuccinyl-CoA:acetate CoA-transferase/0.453
4iawLIZNeutrophil gelatinase-associated lipocalin/0.453
4iqgNAPShort-chain dehydrogenase/reductase SDR/0.453
4jnkNAIL-lactate dehydrogenase A chain1.1.1.270.453
4tqgNDPPutative dTDP-d-glucose 4 6-dehydratase/0.453
4u8jFDAUDP-galactopyranose mutase/0.453
5cwa0GAAnthranilate synthase component 14.1.3.270.453
1h74AGSHomoserine kinase2.7.1.390.452
2g1r3IGRenin3.4.23.150.452
2oapANPType II secretion system protein (GspE-2)/0.452
2rghFADAlpha-Glycerophosphate Oxidase/0.452
3ivgFG5Pantothenate synthetase6.3.2.10.452
3m1vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.452
3m1vCOMMethyl-coenzyme M reductase I subunit beta2.8.4.10.452
4eki0QKHistone-lysine N-methyltransferase, H3 lysine-79 specific2.1.1.430.452
4ipw1G7Mycocyclosin synthase1.14.21.90.452
4k39SAMAnaerobic sulfatase-maturating enzyme1.8.980.452
4n5nNAPAcetoacetyl-CoA reductase1.1.1.360.452
4q73FADBifunctional protein PutA/0.452
5b0oADPFlagellum-specific ATP synthase3.6.3.140.452
5d3qGDPDynamin-13.6.5.50.452
5eccNAPDehydrofolate reductase type I/0.452
1gpdNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.451
1icsFMN12-oxophytodienoate reductase 11.3.1.420.451
1nuuNADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.451
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.451
2xyd3ESAngiotensin-converting enzyme3.2.10.451
3a1nNADNDP-sugar epimerase/0.451
3etgNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.451
3ibqATPPyridoxal kinase/0.451
3vweCOAAlpha-tubulin N-acetyltransferase 1/0.451
4a8v2ANMajor pollen allergen Bet v 1-J/0.451
4b2gV1NUncharacterized protein/0.451
4djaFAD(6-4) photolyase/0.451
4ejmNAPPutative zinc-binding dehydrogenase/0.451
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.451
4gu5FADCryptochrome-1/0.451
4hmvWUBPhenazine biosynthesis protein PhzG1.40.451
4p63NADProbable deoxyhypusine synthase2.5.1.460.451
4u8nFDAUDP-galactopyranose mutase/0.451
4udrFAD5-(hydroxymethyl)furfural oxidase/0.451
4xwtU5PRibonuclease J/0.451
5a88ADPRiboflavin biosynthesis protein RibF2.7.1.260.451
5c41ACPRibokinase/0.451
1ib0NADNADH-cytochrome b5 reductase 31.6.2.20.450
1jkx138Phosphoribosylglycinamide formyltransferase/0.450
1w6hTITPlasmepsin-23.4.23.390.450
2ga9AGSPoly(A) polymerase catalytic subunit2.7.7.190.450
2ii6C5PAlpha-2,3/2,6-sialyltransferase/sialidase/0.450
2iyfERYOleandomycin glycosyltransferase2.4.10.450
2ohvNHLGlutamate racemase/0.450
2p5uNADUDP-glucose 4-epimerase/0.450
2wsiFADFAD synthase2.7.7.20.450
2x0rNADMalate dehydrogenase/0.450
2ztvNADD(-)-3-hydroxybutyrate dehydrogenase/0.450
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.450
3flwFLWMitogen-activated protein kinase 14/0.450
3h4lANPDNA mismatch repair protein PMS1/0.450
3h86AP5Adenylate kinase/0.450
3pw8ACO1,2-phenylacetyl-CoA epoxidase, subunit A1.14.13.1490.450
3wrjCAMCamphor 5-monooxygenase1.14.15.10.450
4dbvNDPGlyceraldehyde-3-phosphate dehydrogenase/0.450
4du82P0Mevalonate diphosphate decarboxylase/0.450
4k7yFMNNADPH dehydrogenase 11.6.99.10.450
4lutDCSAlanine racemase/0.450
4rnwFMNNADPH dehydrogenase 11.6.99.10.450
5a9sNAPPutative dehydrogenase/0.450
5cypGSPSeptin-9/0.450
1adfTADAlcohol dehydrogenase E chain1.1.1.10.449
1b2lNDCAlcohol dehydrogenase1.1.1.10.449
1dnpFADDeoxyribodipyrimidine photo-lyase4.1.99.30.449
1lbcCYZGlutamate receptor 2/0.449
1rfvADPPyridoxal kinase2.7.1.350.449
1u1gBBBUridine phosphorylase2.4.2.30.449
2ahrNAPPyrroline-5-carboxylate reductase/0.449
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.449
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.449
2fj1CTCTetracycline repressor protein class D/0.449
2hm1LIQBeta-secretase 13.4.23.460.449
2i7pACOPantothenate kinase 32.7.1.330.449
2lfoGCHFatty acid-binding protein, liver/0.449
2rbeNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.449
2xfsJ01Uncharacterized protein/0.449
2zdyADP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial2.7.11.20.449
3d3wNAPL-xylulose reductase1.1.1.100.449
3hk1B64Fatty acid-binding protein, adipocyte/0.449
3iahNAPPutative oxoacyl-(Acyl carrier protein) reductase/0.449
3ixp834Ecdysone receptor/0.449
3lqsPSZD-alanine aminotransferase2.6.1.210.449
3oixFMNDihydroorotate dehydrogenase/0.449
3p84FMNPentaerythritol tetranitrate reductase/0.449
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.449
4b4vL34Bifunctional protein FolD/0.449
4m83ERYOleandomycin glycosyltransferase2.4.10.449
4qfyDCPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.449
4zjuNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.449
1hygNAPL-2-hydroxycarboxylate dehydrogenase (NAD(P)(+))/0.448
1p0hACOMycothiol acetyltransferase2.3.1.1890.448
1qyw5SDEstradiol 17-beta-dehydrogenase 11.1.1.620.448
1udcUFMUDP-glucose 4-epimerase5.1.3.20.448
2ejzSAHDiphthine synthase/0.448
2fsvNADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.448
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.448
2iko7IGRenin3.4.23.150.448
2j08FADDeoxyribodipyrimidine photo-lyase4.1.99.30.448
2lbaCHOFatty acid binding protein 6/0.448
2x8hFADThioredoxin glutathione reductase/0.448
2zaxCAMCamphor 5-monooxygenase1.14.15.10.448
3d4pNADL-lactate dehydrogenase 11.1.1.270.448
3fccATPD-alanine--poly(phosphoribitol) ligase subunit 1/0.448
3fhyATPPyridoxal kinase2.7.1.350.448
3l63CAMCamphor 5-monooxygenase1.14.15.10.448
3mk6ACOPantothenate kinase 32.7.1.330.448
3nd1SAHPrecorrin-6A synthase (Deacetylating)/0.448
3ohh3HHBeta-secretase 13.4.23.460.448
3r6sCMPCRP-like cAMP-activated global transcriptional regulator/0.448
3sz0FADSulfide-quinone reductase/0.448
3t2kFADSulfide-quinone reductase/0.448
3ty3GGGHomoisocitrate dehydrogenase1.1.1.870.448
3w2eNADNADH-cytochrome b5 reductase 31.6.2.20.448
4b4dFADFerredoxin-NADP reductase/0.448
4b8wNAPGDP-L-fucose synthase1.1.1.2710.448
4cdmFADDeoxyribodipyrimidine photolyase/0.448
4cvmANPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.448
4dbzNDPPutative ketoacyl reductase1.3.10.448
4dd8BATDisintegrin and metalloproteinase domain-containing protein 83.4.240.448
4eb7PLPCysteine desulfurase IscS 2/0.448
4h6rFDAProline dehydrogenase/0.448
4ke11R6Beta-secretase 13.4.23.460.448
4nd2A3DLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.448
5hs1VORLanosterol 14-alpha demethylase/0.448
1n3sGTPGTP cyclohydrolase 13.5.4.160.447
1rfuADPPyridoxal kinase2.7.1.350.447
1tehNADAlcohol dehydrogenase class-31.1.1.10.447
1u4oNDDL-lactate dehydrogenase1.1.1.270.447
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.447
2e8hSAHDiphthine synthase/0.447
2gtbAZPOrf1ab polyprotein/0.447
2j07HDFDeoxyribodipyrimidine photo-lyase4.1.99.30.447
2znq401Peroxisome proliferator-activated receptor delta/0.447
2zs9ADPPantothenate kinase2.7.1.330.447
3h8bNSYCathepsin L13.4.22.150.447
3in6FMNUncharacterized protein/0.447
3upf0BUPolyprotein/0.447
3zhyFM61-deoxy-D-xylulose 5-phosphate reductoisomerase/0.447
4z0hNADGlyceraldehyde-3-phosphate dehydrogenase GAPC1, cytosolic1.2.1.120.447
5bsfNADPyrroline-5-carboxylate reductase/0.447
1culFOKAdenylate cyclase type 2/0.446
1culFOKAdenylate cyclase type 5/0.446
1f4fTP3Thymidylate synthase/0.446
1fm4DXCMajor pollen allergen Bet v 1-L/0.446
1rj6AZMCarbonic anhydrase 144.2.1.10.446
2ed4NAD4-hydroxyphenylacetate 3-monooxygenase reductase component1.5.1.360.446
2gsdNADFormate dehydrogenase/0.446
2ilvC5PAlpha-2,3/2,6-sialyltransferase/sialidase/0.446
2qjoNADBifunctional NMN adenylyltransferase/Nudix hydrolase2.7.7.10.446
3atyFMNProstaglandin F2a synthase/0.446
3b6zCO7Enoyl reductase LovC10.446
3fr5I4AFatty acid-binding protein, adipocyte/0.446
3iqhTYR_ASP_ILECysteine synthase2.5.1.470.446
3s87ADPRibonucleoside-diphosphate reductase large chain 11.17.4.10.446
3uceNDPDehydrogenase/0.446
3uoyNAP2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.446
4a6nFADTetX family tetracycline inactivation enzyme/0.446
4df2FMNNADPH dehydrogenase/0.446
4egbNADdTDP-glucose 4,6-dehydratase/0.446
4f5yC2EStimulator of interferon genes protein/0.446
4hhz15SPoly [ADP-ribose] polymerase 12.4.2.300.446
4is3NAD3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 21.17.98.10.446
4oxyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.446
4tlzNAPKtzI/0.446
4xiwAZMCarbonic anhydrase, alpha type/0.446
4z38FMNMlnA/0.446
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.446
1drhNAPDihydrofolate reductase1.5.1.30.445
1n2eAPCPantothenate synthetase6.3.2.10.445
1qrpHH0Pepsin A-43.4.23.10.445
1t86CAMCamphor 5-monooxygenase1.14.15.10.445
1wngSAHDiphthine synthase/0.445
1z48FMNNADPH dehydrogenase/0.445
2a1nCAMCamphor 5-monooxygenase1.14.15.10.445
2a7r5GPGMP reductase 2/0.445
2bz5AB4Heat shock protein HSP 90-alpha/0.445
2o23NAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.445
2oc4IMHPurine nucleoside phosphorylase2.4.2.10.445
2oc9IMHPurine nucleoside phosphorylase2.4.2.10.445
3bbhSFGRibosomal RNA small subunit methyltransferase Nep12.1.10.445
3bc3OPTCathepsin L13.4.22.150.445
3h3cP1EProtein-tyrosine kinase 2-beta2.7.10.20.445
3h3r14HCollagen type IV alpha-3-binding protein/0.445
3hgrFMN12-oxophytodienoate reductase 11.3.1.420.445
3kxw1ZZSaframycin Mx1 synthetase B/0.445
3nl6TPSUncharacterized protein/0.445
3otbDGTProbable tRNA(His) guanylyltransferase2.7.7.790.445
3ruhNADUDP-N-acetylglucosamine 4-epimerase/0.445
4eu9COASuccinyl-CoA:acetate CoA-transferase/0.445
4h1vGNPDynamin-1-like protein3.6.5.50.445
4k28NADShikimate dehydrogenase family protein/0.445
4rnuFMNNADPH dehydrogenase 11.6.99.10.445
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.444
1mj9COAHistone acetyltransferase ESA1/0.444
1ojtFADDihydrolipoyl dehydrogenase/0.444
1qlhNADAlcohol dehydrogenase E chain1.1.1.10.444
1r6uTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.444
1t88CAMCamphor 5-monooxygenase1.14.15.10.444
1ty9FMNPhenazine biosynthesis protein PhzG1.40.444
1yb5NAPQuinone oxidoreductase1.6.5.50.444
2b53D23Cyclin-dependent kinase 22.7.11.220.444
2dphNADFormaldehyde dismutase/0.444
2ejvNADL-threonine 3-dehydrogenase/0.444
2ijmATPFocal adhesion kinase 12.7.10.20.444
2j9gANPBiotin carboxylase6.3.4.140.444
2q1uNADPutative nucleotide sugar epimerase/ dehydratase/0.444
2qimZEAClass 10 plant pathogenesis-related protein/0.444
2x9dITCTetracycline repressor protein class D/0.444
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.444
3c212BADNA integrity scanning protein DisA/0.444
3fhxPLPPyridoxal kinase2.7.1.350.444
3fwiCAMCamphor 5-monooxygenase1.14.15.10.444
3hgsFMN12-oxophytodienoate reductase 31.3.1.420.444
3triNAPPyrroline-5-carboxylate reductase/0.444
4anwO92Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
4cd2FOLDihydrofolate reductase1.5.1.30.444
4d89BXDBeta-secretase 13.4.23.460.444
4eph0RKCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.444
4gddNAIUDP-galactopyranose mutase/0.444
4i5vB4PDiadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase 2/0.444
4kkyCAMCamphor 5-monooxygenase1.14.15.10.444
4qxr1YEStimulator of interferon genes protein/0.444
5einNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.444
5f8eSAHPossible transcriptional regulatory protein/0.444
1dz4CAMCamphor 5-monooxygenase1.14.15.10.443
1f8fNADBenzyl alcohol dehydrogenase/0.443
1qbqHFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.443
1qbqHFPProtein farnesyltransferase subunit beta2.5.1.580.443
1qcjAPTAntiviral protein I3.2.2.220.443
1qr0COA4'-phosphopantetheinyl transferase sfp2.7.80.443
1qy8RDIEndoplasmin/0.443
1vhzAPRADP compounds hydrolase NudE3.6.10.443
1x1dSAHC-20 methyltransferase/0.443
1ykfNAPNADP-dependent isopropanol dehydrogenase1.1.1.800.443
2a92NAIL-lactate dehydrogenase/0.443
2b4rAESGlyceraldehyde-3-phosphate dehydrogenase/0.443
2d3aADPGlutamine synthetase root isozyme 36.3.1.20.443
2rcyNAPPyrroline-5-carboxylate reductase/0.443
2x7bCOAN-alpha-acetyltransferase2.3.10.443
2y4gTIRTamL/0.443
2ztlNADD(-)-3-hydroxybutyrate dehydrogenase/0.443
3kjgADPCO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC/0.443
3oquA8SAbscisic acid receptor PYL9/0.443
3pvt3HC1,2-phenylacetyl-CoA epoxidase, subunit A1.14.13.1490.443
3vdqNAD3-hydroxybutyrate dehydrogenase/0.443
4b00I6XBeta-secretase 13.4.23.460.443
4b0qGMFBeta-secretase 13.4.23.460.443
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.443
4e2bFMNDehydrogenase/0.443
4fm80UQBeta-secretase 13.4.23.460.443
4fv4EK7Mitogen-activated protein kinase 12.7.11.240.443
4lcg1WMUDP-3-O-acyl-N-acetylglucosamine deacetylase/0.443
4qnwFMNChanoclavine-I aldehyde reductase easA/0.443
5c77SAHProtein arginine N-methyltransferase SFM1/0.443
5dmhADP3-oxo-tetronate kinase/0.443
5iqdGNPBifunctional AAC/APH2.3.10.443
5jy1NADPutative short-chain dehydrogenase/reductase/0.443
1iqrFADDeoxyribodipyrimidine photo-lyase4.1.99.30.442
1j21ATPArgininosuccinate synthase/0.442
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.442
1ma0NADAlcohol dehydrogenase class-31.1.1.10.442
1ndhFADNADH-cytochrome b5 reductase 31.6.2.20.442
1xg5NAPDehydrogenase/reductase SDR family member 11/0.442
1yqdNAPSinapyl alcohol dehydrogenase/0.442
1z7yAA5Cysteine synthase 12.5.1.470.442
2aqhNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
2b8l5HABeta-secretase 13.4.23.460.442
2jkvNAP6-phosphogluconate dehydrogenase, decarboxylating1.1.1.440.442
2q3rFMN12-oxophytodienoate reductase 11.3.1.420.442
2vbdV10Isopenicillin N synthase1.21.3.10.442
2z9dFMNFMN-dependent NADH-azoreductase/0.442
2zfaFMNLactate oxidase/0.442
3etdNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.442
3f63GTXGlutathione transferase GST1-4/0.442
3kjrNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.442
3mvqNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.442
3o0qADNVitamin B12-dependent ribonucleotide reductase/0.442
3rpeFADPutative modulator of drug activity/0.442
3sopGDPNeuronal-specific septin-3/0.442
3w4yFADMitochondrial FAD-linked sulfhydryl oxidase ERV11.8.3.20.442
4a4zANPAntiviral helicase SKI23.6.4.130.442
4a87NARMajor pollen allergen Bet v 1-A/0.442
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.442
4g090VDHistidinol dehydrogenase/0.442
4ge40KEKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.442
4l98LRGPeroxisome proliferator-activated receptor gamma/0.442
4ure1PSCyclohexanol dehydrogenase/0.442
1d0lBLGMembrane-bound lytic murein transglycosylase B4.2.2.n10.441
1dz6CAMCamphor 5-monooxygenase1.14.15.10.441
1j49NADD-lactate dehydrogenase1.1.1.280.441
1lsjNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.441
1m78NDPDihydrofolate reductase1.5.1.30.441
1nahNADUDP-glucose 4-epimerase5.1.3.20.441
1pmn984Mitogen-activated protein kinase 102.7.11.240.441
1qy5NECEndoplasmin/0.441
1vfrFMNMajor NAD(P)H-flavin oxidoreductase1.6.990.441
1w34FADFerredoxin--NADP reductase1.18.1.20.441
2b4tAESGlyceraldehyde-3-phosphate dehydrogenase/0.441
2bpoNAPNADPH--cytochrome P450 reductase/0.441
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.441
2briANPUridylate kinase2.7.4.220.441
2emuSAHDiphthine synthase/0.441
2gnfY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
2pwlACPFibroblast growth factor receptor 2/0.441
2vn0TDZCytochrome P450 2C8/0.441
2xgs44PUncharacterized protein/0.441
3eksCY9Actin-5C/0.441
3h3qH13Collagen type IV alpha-3-binding protein/0.441
3inmNDPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.441
3r9iADPSeptum site-determining protein MinD/0.441
3tz3B36Acetyl-CoA carboxylase/0.441
3w2wATPCRISPR system Cmr subunit Cmr2/0.441
3wv9FEGHmd co-occurring protein HcgE/0.441
4azmT4BFatty acid-binding protein, epidermal/0.441
4cdmFO1Deoxyribodipyrimidine photolyase/0.441
4ew2DXYTrifunctional purine biosynthetic protein adenosine-32.1.2.20.441
4fxy0W2Neurolysin, mitochondrial3.4.24.160.441
4jia1K3Tyrosine-protein kinase JAK2/0.441
4nd3NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.441
4x3mADNRNA 2'-O ribose methyltransferase/0.441
5cyoGDPSeptin-9/0.441
5fs7FADApoptosis-inducing factor 1, mitochondrial1.1.10.441
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.440
1hzjUD1UDP-glucose 4-epimerase/0.440
1lf2R37Plasmepsin-23.4.23.390.440
1uu9BI33-phosphoinositide-dependent protein kinase 12.7.11.10.440
1yqxNAPSinapyl alcohol dehydrogenase/0.440
1zxnADPDNA topoisomerase 2-alpha5.99.1.30.440
2a1oCAMCamphor 5-monooxygenase1.14.15.10.440
2aqiNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
2b4qNAPRhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase1.1.1.1000.440
2cndFADNitrate reductase [NADH]1.7.1.10.440
2fhnBNIAvidin-related protein 4/5/0.440
2g5w8PG12-oxophytodienoate reductase 31.3.1.420.440
2hsdNAD3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.440
2jb4A14Isopenicillin N synthase1.21.3.10.440
2rhgIGPTryptophan synthase alpha chain/0.440
2uxoTACHTH-type transcriptional regulator TtgR/0.440
2vkeTACTetracycline repressor protein class D/0.440
2vyqFADFerredoxin--NADP reductase1.18.1.20.440
2xcmADPCytosolic heat shock protein 90/0.440
2xpuTDCTetracycline repressor protein class D/0.440
3flkNAITartrate dehydrogenase/decarboxylase1.1.1.930.440
3fwjCAMCamphor 5-monooxygenase1.14.15.10.440
3g49NAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.440
3gyeFMNDihydroorotate dehydrogenase (fumarate)/0.440
3k5c0BIBeta-secretase 13.4.23.460.440
3mdmFJZCholesterol 24-hydroxylase/0.440
3tscNADUncharacterized protein/0.440
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.440
4dpuAGSMevalonate diphosphate decarboxylase/0.440
4fw8NAI3-oxoacyl-(Acyl-carrier-protein) reductase/0.440
4h9tHL4Phosphotriesterase/0.440
4x5iFOLDihydrofolate reductase1.5.1.30.440
5a0112VO-glycosyltransferase/0.440