sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3ml2 | SU0 | Carbonic anhydrase 2 | 4.2.1.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3ml2 | SU0 | Carbonic anhydrase 2 | 4.2.1.1 | 1.000 | |
| 4ilx | 1EZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.924 | |
| 3bet | CTF | Carbonic anhydrase 2 | 4.2.1.1 | 0.880 | |
| 4ito | MPX | Carbonic anhydrase 2 | 4.2.1.1 | 0.847 | |
| 3n3j | WWV | Carbonic anhydrase 2 | 4.2.1.1 | 0.828 | |
| 3oim | VZ5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.825 | |
| 3n4b | WWZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.818 | |
| 3mzc | S6I | Carbonic anhydrase 2 | 4.2.1.1 | 0.797 | |
| 3mna | DWH | Carbonic anhydrase 2 | 4.2.1.1 | 0.783 | |
| 4itp | 1GD | Carbonic anhydrase 2 | 4.2.1.1 | 0.779 | |
| 2wej | FB2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.773 | |
| 3daz | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.770 | |
| 3mmf | D9H | Carbonic anhydrase 2 | 4.2.1.1 | 0.766 | |
| 3oys | OYS | Carbonic anhydrase 2 | 4.2.1.1 | 0.755 | |
| 1bnt | AL2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.752 | |
| 1g1d | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.751 | |
| 3k2f | NKX | Carbonic anhydrase 2 | 4.2.1.1 | 0.748 | |
| 1i90 | INM | Carbonic anhydrase 2 | 4.2.1.1 | 0.747 | |
| 3mho | J43 | Carbonic anhydrase 2 | 4.2.1.1 | 0.746 | |
| 3qyk | IE2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.743 | |
| 3dd8 | 2C7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.739 | |
| 1cil | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.735 | |
| 4bf6 | X0Q | Carbonic anhydrase 2 | 4.2.1.1 | 0.735 | |
| 1kwr | SG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.731 | |
| 3n0n | P9B | Carbonic anhydrase 2 | 4.2.1.1 | 0.727 | |
| 2weg | FBV | Carbonic anhydrase 2 | 4.2.1.1 | 0.726 | |
| 2h15 | B19 | Carbonic anhydrase 2 | 4.2.1.1 | 0.723 | |
| 4iwz | 1GO | Carbonic anhydrase 2 | 4.2.1.1 | 0.716 | |
| 3m2n | J74 | Carbonic anhydrase 2 | 4.2.1.1 | 0.714 | |
| 3eft | 3BS | Carbonic anhydrase 2 | 4.2.1.1 | 0.713 | |
| 2weh | FB1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.712 | |
| 1a42 | BZU | Carbonic anhydrase 2 | 4.2.1.1 | 0.706 | |
| 1bn4 | AL9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.706 | |
| 1if4 | FBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.706 | |
| 3m98 | E02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.705 | |
| 3s8x | E59 | Carbonic anhydrase 2 | 4.2.1.1 | 0.702 | |
| 1bnw | TPD | Carbonic anhydrase 2 | 4.2.1.1 | 0.698 | |
| 3oy0 | OY0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.692 | |
| 1bnn | AL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.689 | |
| 1bnm | AL8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.687 | |
| 3sbh | E65 | Carbonic anhydrase 2 | 4.2.1.1 | 0.687 | |
| 3d9z | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.686 | |
| 3oyq | OYQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.681 | |
| 3sbi | E90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.681 | |
| 1cny | EG3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.679 | |
| 1bn1 | AL5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.678 | |
| 4kni | E1E | Carbonic anhydrase 2 | 4.2.1.1 | 0.678 | |
| 1i9n | IOA | Carbonic anhydrase 2 | 4.2.1.1 | 0.676 | |
| 1if6 | FBU | Carbonic anhydrase 2 | 4.2.1.1 | 0.672 | |
| 1cnx | EG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.665 | |
| 1i91 | INQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.665 | |
| 1oq5 | CEL | Carbonic anhydrase 2 | 4.2.1.1 | 0.665 | |
| 2eu3 | FF3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.665 | |
| 1okm | SAB | Carbonic anhydrase 2 | 4.2.1.1 | 0.664 | |
| 3b4f | TUO | Carbonic anhydrase 2 | 4.2.1.1 | 0.662 | |
| 3myq | E27 | Carbonic anhydrase 2 | 4.2.1.1 | 0.661 | |
| 2weo | FBW | Carbonic anhydrase 2 | 4.2.1.1 | 0.660 | |
| 2q1q | OSP | Carbonic anhydrase 2 | 4.2.1.1 | 0.656 | |
| 1bnv | AL7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.655 | |
| 4dz7 | D02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.655 | |
| 2pow | I7C | Carbonic anhydrase 2 | 4.2.1.1 | 0.654 | |
| 3ffp | LC1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.654 | |
| 3dcw | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.653 | |
| 4bf1 | 9FK | Carbonic anhydrase 2 | 4.2.1.1 | 0.653 | |
| 1cnw | EG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.652 | |
| 1zsb | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.652 | |
| 3dd0 | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.650 | |
| 1i8z | INL | Carbonic anhydrase 2 | 4.2.1.1 | 0.649 | |
| 3igp | DT7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.647 | |
| 3n2p | AYX | Carbonic anhydrase 2 | 4.2.1.1 | 0.647 | |
| 3f4x | KLT | Carbonic anhydrase 2 | 4.2.1.1 | 0.646 | |
| 2h4n | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.645 | |
| 1bnq | AL4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.644 | |
| 3nb5 | R21 | Carbonic anhydrase 2 | 4.2.1.1 | 0.643 | |
| 3ni5 | C1H | Carbonic anhydrase 2 | 4.2.1.1 | 0.643 | |
| 1g52 | F2B | Carbonic anhydrase 2 | 4.2.1.1 | 0.642 | |
| 4k13 | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.642 | |
| 4knj | E1F | Carbonic anhydrase 2 | 4.2.1.1 | 0.642 | |
| 3sax | E50 | Carbonic anhydrase 2 | 4.2.1.1 | 0.641 | |
| 3d8w | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.640 | |
| 3m5e | JDR | Carbonic anhydrase 2 | 4.2.1.1 | 0.639 | |
| 3oik | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.639 | |
| 1g54 | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.638 | |
| 3s9t | E49 | Carbonic anhydrase 2 | 4.2.1.1 | 0.635 | |
| 3m40 | J45 | Carbonic anhydrase 2 | 4.2.1.1 | 0.632 | |
| 4kap | 1QV | Carbonic anhydrase 2 | 4.2.1.1 | 0.630 | |
| 3mhi | J90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.629 | |
| 3v2j | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.627 | |
| 4mo8 | 2VQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.627 | |
| 4m2r | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.625 | |
| 3dc3 | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.624 | |
| 3l14 | I7B | Carbonic anhydrase 2 | 4.2.1.1 | 0.623 | |
| 1if5 | FBT | Carbonic anhydrase 2 | 4.2.1.1 | 0.622 | |
| 3dcs | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.622 | |
| 4pxx | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.617 | |
| 3mhl | J71 | Carbonic anhydrase 2 | 4.2.1.1 | 0.612 | |
| 1ttm | 667 | Carbonic anhydrase 2 | 4.2.1.1 | 0.611 | |
| 3m2y | BE0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.610 | |
| 3t84 | SG6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.610 | |
| 1kwq | SG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.605 | |
| 1g4j | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.604 | |
| 3kig | DA4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.603 | |
| 3po6 | DT9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.603 | |
| 2x7t | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.600 | |
| 3dcc | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.600 | |
| 1xq0 | 4TR | Carbonic anhydrase 2 | 4.2.1.1 | 0.599 | |
| 3p5l | IT5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.599 | |
| 4n16 | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.599 | |
| 4m2v | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.598 | |
| 3bl1 | BL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.597 | |
| 1xpz | 4TZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.594 | |
| 3m67 | E36 | Carbonic anhydrase 2 | 4.2.1.1 | 0.593 | |
| 1g4o | BSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.591 | |
| 1okn | STB | Carbonic anhydrase 2 | 4.2.1.1 | 0.591 | |
| 2x7u | WZA | Carbonic anhydrase 2 | 4.2.1.1 | 0.591 | |
| 3m96 | E38 | Carbonic anhydrase 2 | 4.2.1.1 | 0.591 | |
| 2wd2 | MS5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.589 | |
| 5flt | VJJ | Carbonic anhydrase 2 | 4.2.1.1 | 0.585 | |
| 1eou | SMS | Carbonic anhydrase 2 | 4.2.1.1 | 0.584 | |
| 1okl | MNS | Carbonic anhydrase 2 | 4.2.1.1 | 0.576 | |
| 3mdz | EZL | Carbonic anhydrase 7 | 4.2.1.1 | 0.572 | |
| 4kp8 | E1G | Carbonic anhydrase 12 | 4.2.1.1 | 0.572 | |
| 1bn3 | AL6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.570 | |
| 1if8 | SBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.567 | |
| 1jd0 | AZM | Carbonic anhydrase 12 | 4.2.1.1 | 0.567 | |
| 3hku | TOR | Carbonic anhydrase 2 | 4.2.1.1 | 0.567 | |
| 3t82 | SG4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.567 | |
| 3znc | BZ1 | Carbonic anhydrase 4 | 4.2.1.1 | 0.565 | |
| 4ht2 | V50 | Carbonic anhydrase 12 | 4.2.1.1 | 0.565 | |
| 1g45 | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.561 | |
| 3t85 | SG7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.560 | |
| 1bnu | AL3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.556 | |
| 1i9q | IOF | Carbonic anhydrase 2 | 4.2.1.1 | 0.554 | |
| 4lu3 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.554 | |
| 1if7 | SBR | Carbonic anhydrase 2 | 4.2.1.1 | 0.548 | |
| 4x5s | AZM | Carbonic anhydrase (Carbonate dehydratase) | / | 0.541 | |
| 4kp5 | E1F | Carbonic anhydrase 12 | 4.2.1.1 | 0.531 | |
| 3f7u | AG4 | Carbonic anhydrase 4 | 4.2.1.1 | 0.529 | |
| 1rj6 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.528 | |
| 4knn | E1F | Carbonic anhydrase 13 | 4.2.1.1 | 0.528 | |
| 4k0z | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.525 | |
| 4uov | AZM | Carbonate dehydratase | / | 0.525 | |
| 3mhc | ARZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.524 | |
| 3f7b | AG5 | Carbonic anhydrase 4 | 4.2.1.1 | 0.523 | |
| 4knm | E1E | Carbonic anhydrase 13 | 4.2.1.1 | 0.523 | |
| 3fw3 | ETS | Carbonic anhydrase 4 | 4.2.1.1 | 0.518 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.510 | |
| 1yda | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.508 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.508 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.506 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.505 | |
| 4k0t | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.501 | |
| 3lxe | TOR | Carbonic anhydrase 1 | 4.2.1.1 | 0.500 | |
| 3dbu | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.497 | |
| 4iae | 1DX | Alr2278 protein | / | 0.497 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.496 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.496 | |
| 5fl4 | 9FK | Carbonic anhydrase 9 | 4.2.1.1 | 0.496 | |
| 3rz8 | RZ8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.495 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.492 | |
| 2yoz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.492 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.492 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.491 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.490 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.490 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.490 | |
| 3zs7 | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.490 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.489 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.488 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.488 | |
| 4c49 | HCY | Corticosteroid-binding globulin | / | 0.488 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.487 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.486 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.485 | |
| 3akm | 11D | Fatty acid-binding protein, intestinal | / | 0.485 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.485 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.485 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.485 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.484 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.484 | |
| 3nl6 | TPS | Uncharacterized protein | / | 0.484 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.482 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.482 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.482 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.482 | |
| 3hdy | GDU | UDP-galactopyranose mutase | / | 0.482 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.482 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.482 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.481 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.481 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.480 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.480 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.480 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.480 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.480 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.479 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.479 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.479 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.478 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.478 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.478 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.478 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.477 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.477 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.477 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.476 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.476 | |
| 2dxd | ANP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.475 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.475 | |
| 1s64 | 778 | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.474 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.474 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.474 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.474 | |
| 4gd4 | 0WS | Lysine-specific demethylase 4A | 1.14.11 | 0.474 | |
| 1obb | NAD | Alpha-glucosidase | 3.2.1.20 | 0.473 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.473 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.473 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.473 | |
| 3pdq | KC6 | Lysine-specific demethylase 4A | 1.14.11 | 0.473 | |
| 3zht | TD9 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.473 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.472 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.472 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.472 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.472 | |
| 4ejv | LCL | Transcriptional regulator TcaR | / | 0.472 | |
| 5c1d | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.472 | |
| 6std | MS2 | Scytalone dehydratase | 4.2.1.94 | 0.472 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.471 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.471 | |
| 3dd1 | 25D | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.471 | |
| 4wdg | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.471 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.470 | |
| 1u1c | BAU | Uridine phosphorylase | 2.4.2.3 | 0.470 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.470 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.470 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.470 | |
| 4iah | 1DX | Alr2278 protein | / | 0.470 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.470 | |
| 4n1g | CEI | Obelin | / | 0.470 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.469 | |
| 1qpf | 858 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.469 | |
| 3akn | 11D | Fatty acid-binding protein, intestinal | / | 0.469 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.469 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.469 | |
| 4dbc | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.469 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.469 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.469 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.469 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.468 | |
| 2idk | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.468 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.468 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.468 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.468 | |
| 4ise | 1FW | Glucokinase | 2.7.1.2 | 0.468 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.468 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.467 | |
| 1nzx | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.467 | |
| 3gka | FMN | N-ethylmaleimide reductase | / | 0.467 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.467 | |
| 1mxf | MTX | Putative pteridine reductase 2 | / | 0.466 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.466 | |
| 2d3a | ADP | Glutamine synthetase root isozyme 3 | 6.3.1.2 | 0.466 | |
| 2vrb | NAP | Triphenylmethane reductase | / | 0.466 | |
| 3cav | CI2 | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.466 | |
| 4xr9 | NAD | CalS8 | / | 0.466 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.465 | |
| 1q45 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.465 | |
| 1sa4 | JAN | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.465 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.465 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.465 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.465 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.464 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.464 | |
| 2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.464 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.464 | |
| 2fxf | ACO | Diamine acetyltransferase 1 | / | 0.464 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.464 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.464 | |
| 3mj4 | URM | UDP-galactopyranose mutase | / | 0.464 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.463 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.463 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 1o97 | FAD | Electron transfer flavoprotein subunit alpha | / | 0.463 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.463 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.463 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.463 | |
| 4xoq | F42 | Coenzyme F420:L-glutamate ligase | / | 0.463 | |
| 1a9z | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.462 | |
| 1bzm | MZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.462 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.462 | |
| 2e9d | B76 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.462 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.462 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.462 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.462 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.462 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
| 4a6r | TA8 | Probable aminotransferase | / | 0.462 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.462 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.461 | |
| 2zvc | SAH | Precorrin-3 C17-methyltransferase | / | 0.461 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.461 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.461 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.461 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.460 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.460 | |
| 1zdw | FLV | Prenyltransferase | / | 0.460 | |
| 2vtd | LKM | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.460 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.460 | |
| 3pl8 | FAD | Pyranose 2-oxidase | / | 0.460 | |
| 3ruh | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.460 | |
| 4fhj | 0TZ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.460 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.459 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.459 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.459 | |
| 2hs6 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.459 | |
| 2ohv | NHL | Glutamate racemase | / | 0.459 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.459 | |
| 2q3o | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.459 | |
| 3fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.459 | |
| 3fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.459 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.459 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.459 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.459 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.458 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.458 | |
| 1f4e | TPR | Thymidylate synthase | / | 0.458 | |
| 1ld8 | U49 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.458 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.458 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.458 | |
| 2v59 | LZK | Biotin carboxylase | 6.3.4.14 | 0.458 | |
| 1til | ATP | Anti-sigma F factor | / | 0.457 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.457 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.457 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.457 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.457 | |
| 3qj0 | QI3 | Botulinum neurotoxin type A | 3.4.24.69 | 0.457 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.457 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.457 | |
| 4e2d | FMN | Dehydrogenase | / | 0.457 | |
| 4lut | DCS | Alanine racemase | / | 0.457 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.456 | |
| 3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.456 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.456 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.456 | |
| 3w3l | RX8 | Toll-like receptor 8 | / | 0.456 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.456 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 4jic | FMN | GTN Reductase | / | 0.456 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.456 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.456 | |
| 1jzq | ILA | Isoleucine--tRNA ligase | 6.1.1.5 | 0.455 | |
| 1rc4 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.455 | |
| 2iya | ZIO | Oleandomycin glycosyltransferase | / | 0.455 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 3keq | NAD | Redox-sensing transcriptional repressor Rex | / | 0.455 | |
| 3n19 | FNR | Xenobiotic reductase | / | 0.455 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.455 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.455 | |
| 4o7u | THF | Thymidylate synthase | / | 0.455 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.455 | |
| 1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.454 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.454 | |
| 2j9l | ATP | H(+)/Cl(-) exchange transporter 5 | / | 0.454 | |
| 2v4l | ABJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.454 | |
| 3m2v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.454 | |
| 3q7f | ED2 | Uncharacterized protein | / | 0.454 | |
| 3sf6 | FDA | Glutaryl-CoA dehydrogenase | / | 0.454 | |
| 3sfy | 3FY | Uncharacterized protein | / | 0.454 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.454 | |
| 4dvi | 2IW | Tankyrase-1 | 2.4.2.30 | 0.454 | |
| 4nv1 | 4TG | Formyl transferase | / | 0.454 | |
| 4u7w | NDP | MxaA | / | 0.454 | |
| 4zj8 | SUV | Orexin receptor type 1 | / | 0.454 | |
| 1bl4 | AP1 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.453 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.453 | |
| 1mmk | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.453 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.453 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.453 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.453 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.453 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 3r1r | ATP | Ribonucleoside-diphosphate reductase 1 subunit alpha | 1.17.4.1 | 0.453 | |
| 3rud | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.453 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.453 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.453 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.453 | |
| 4x5g | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1b5e | DCM | Deoxycytidylate 5-hydroxymethyltransferase | 2.1.2.8 | 0.452 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.452 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 1vjt | NAD | Alpha-glucosidase, putative | / | 0.452 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.452 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.452 | |
| 2a84 | ATP | Pantothenate synthetase | 6.3.2.1 | 0.452 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.452 | |
| 2e8u | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.452 | |
| 2hdj | NDP | Aldo-keto reductase family 1 member C2 | / | 0.452 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.452 | |
| 2q3r | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.452 | |
| 2ydb | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.452 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.452 | |
| 3rf7 | NAD | Iron-containing alcohol dehydrogenase | / | 0.452 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.452 | |
| 4e2b | FMN | Dehydrogenase | / | 0.452 | |
| 4ea1 | 3RX | Dehydrosqualene synthase | / | 0.452 | |
| 4r81 | FMN | Predicted NADH dehydrogenase | / | 0.452 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.452 | |
| 5fd8 | A5A | Putative carboxypeptidase yocD | / | 0.452 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.452 | |
| 1ni1 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.451 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.451 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.451 | |
| 2cmo | M1L | Glutamate receptor 2 | / | 0.451 | |
| 2e77 | FMN | Lactate oxidase | / | 0.451 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.451 | |
| 3f63 | GTX | Glutathione transferase GST1-4 | / | 0.451 | |
| 3fbu | COA | Acetyltransferase, GNAT family | / | 0.451 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.451 | |
| 3k1w | BFX | Renin | 3.4.23.15 | 0.451 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.451 | |
| 4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 4id9 | NAD | Putative UDP-glucose 4-epimerase | / | 0.451 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.451 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.451 | |
| 1icq | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.450 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.450 | |
| 2b3v | ACO | Diamine acetyltransferase 1 | / | 0.450 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.450 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.450 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.450 | |
| 2vkv | TDC | Tetracycline repressor protein class D | / | 0.450 | |
| 2xb9 | XNW | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.450 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.450 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.450 | |
| 3biy | 01K | Histone acetyltransferase p300 | / | 0.450 | |
| 3da2 | 4MD | Carbonic anhydrase 13 | 4.2.1.1 | 0.450 | |
| 3fvl | BHK | Carboxypeptidase A1 | 3.4.17.1 | 0.450 | |
| 4bfy | ZVY | Pantothenate kinase | 2.7.1.33 | 0.450 | |
| 4i13 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 4jfi | 1KT | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.450 | |
| 4lnb | ED5 | CaaX farnesyltransferase beta subunit Ram1 | / | 0.450 | |
| 4m0f | 1YK | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 4pt0 | NAD | Aldehyde dehydrogenase | / | 0.450 | |
| 4rnu | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.450 | |
| 4v12 | POG | MaoC like domain protein | / | 0.450 | |
| 5dw6 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.450 | |
| 1beu | IPL | Tryptophan synthase alpha chain | / | 0.449 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.449 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.449 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.449 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.449 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.449 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.449 | |
| 2pak | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.449 | |
| 2qc8 | ADP | Glutamine synthetase | 6.3.1.2 | 0.449 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.449 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.449 | |
| 3zhs | TD6 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.449 | |
| 4isg | 1FY | Glucokinase | 2.7.1.2 | 0.449 | |
| 4uoc | NCN | CinA-like protein | / | 0.449 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.449 | |
| 1c7o | PPG | Hemolysin | / | 0.448 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 1ee9 | NAD | Methylenetetrahydrofolate dehydrogenase [NAD(+)] | 1.5.1.15 | 0.448 | |
| 1foa | UD1 | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | 2.4.1.101 | 0.448 | |
| 1u1d | 181 | Uridine phosphorylase | 2.4.2.3 | 0.448 | |
| 1vkg | CRI | Histone deacetylase 8 | 3.5.1.98 | 0.448 | |
| 1wzi | NDP | Malate dehydrogenase | / | 0.448 | |
| 1yry | MSG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.448 | |
| 2ab8 | MTP | Adenosine kinase | 2.7.1.20 | 0.448 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.448 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 3euf | BAU | Uridine phosphorylase 1 | / | 0.448 | |
| 3ha7 | B32 | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.448 | |
| 3nd6 | ATP | Phosphopantetheine adenylyltransferase | / | 0.448 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.448 | |
| 3zhu | TD8 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.448 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 4ej1 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.448 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.448 | |
| 4rnw | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.448 | |
| 4xba | 5GP | Aprataxin-like protein | 3 | 0.448 | |
| 5kgp | ACO | Predicted acetyltransferase | / | 0.448 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.447 | |
| 1cju | FOK | Adenylate cyclase type 2 | / | 0.447 | |
| 1cju | FOK | Adenylate cyclase type 5 | / | 0.447 | |
| 1kfb | IGP | Tryptophan synthase alpha chain | / | 0.447 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.447 | |
| 1r6t | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.447 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.447 | |
| 2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.447 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 3hxe | BD8 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.447 | |
| 3inr | GDU | UDP-galactopyranose mutase | 5.4.99.9 | 0.447 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.447 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.447 | |
| 3qvr | FAD | Glucose oxidase | 1.1.3.4 | 0.447 | |
| 3rvh | HQ2 | Lysine-specific demethylase 4A | 1.14.11 | 0.447 | |
| 4ap1 | NAP | Steroid monooxygenase | / | 0.447 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.447 | |
| 4fwe | FAD | Lysine-specific histone demethylase 1B | 1 | 0.447 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 4h6k | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.447 | |
| 4y17 | LAE | Transcriptional regulator of ftsQAZ gene cluster | / | 0.447 | |
| 4yco | FMN | tRNA-dihydrouridine(16) synthase | / | 0.447 | |
| 5c4f | UPG | Histo-blood group ABO system transferase | / | 0.447 | |
| 5iw5 | NMN | NADH pyrophosphatase | / | 0.447 | |
| 1esn | ANP | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.446 | |
| 1kp3 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.446 | |
| 1q20 | PLO | Sulfotransferase family cytosolic 2B member 1 | 2.8.2.2 | 0.446 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.446 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.446 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.446 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.446 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.446 | |
| 3w0u | HPW | Lactoylglutathione lyase | 4.4.1.5 | 0.446 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 5a01 | 12V | O-glycosyltransferase | / | 0.446 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.445 | |
| 1b8u | NAD | Malate dehydrogenase | / | 0.445 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 1ld7 | U66 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.445 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.445 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.445 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.445 | |
| 1ra8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1rf7 | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1wnz | 2VA | Isoleucine--tRNA ligase | 6.1.1.5 | 0.445 | |
| 2g0n | GDP | Ras-related C3 botulinum toxin substrate 3 | / | 0.445 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.445 | |
| 2hps | CTZ | Ca2+-triggered coelenterazine-binding protein 1 | / | 0.445 | |
| 2lfo | GCH | Fatty acid-binding protein, liver | / | 0.445 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.445 | |
| 2std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.445 | |
| 2xda | JPS | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.445 | |
| 3c35 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.445 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.445 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.445 | |
| 3px2 | T3Q | dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase | 2.1.1.235 | 0.445 | |
| 4ba5 | PXG | Probable aminotransferase | / | 0.445 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.445 | |
| 4f5d | C2E | Stimulator of interferon genes protein | / | 0.445 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.445 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.445 | |
| 4j7h | TRH | PCZA361.3 | / | 0.445 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.445 | |
| 4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.445 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.444 | |
| 1ejb | INJ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.444 | |
| 1kw9 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.444 | |
| 1vji | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.444 | |
| 1w76 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 2ed4 | NAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.444 | |
| 2fk8 | SAM | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.444 | |
| 2lba | CHO | Fatty acid binding protein 6 | / | 0.444 | |
| 2pob | GW4 | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 2rdn | 1PL | 1-deoxypentalenic acid 11-beta-hydroxylase | 1.14.11.35 | 0.444 | |
| 2vqo | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.444 | |
| 2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 2zsh | GA3 | Gibberellin receptor GID1A | 3 | 0.444 | |
| 3eku | CY9 | Actin-5C | / | 0.444 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.444 | |
| 3mdd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.444 | |
| 4drk | I63 | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.444 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.444 | |
| 4ifn | 12O | Kelch-like ECH-associated protein 1 | / | 0.444 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.444 | |
| 4rel | KMP | Glycosyltransferase | / | 0.444 | |
| 1aka | PLP | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.443 | |
| 1ege | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.443 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.443 | |
| 2ejz | SAH | Diphthine synthase | / | 0.443 | |
| 2yp0 | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.443 | |
| 3bj8 | COA | Diamine acetyltransferase 1 | / | 0.443 | |
| 3eo8 | FMN | Putative nitroreductase | / | 0.443 | |
| 3fr2 | 8CA | Fatty acid-binding protein, adipocyte | / | 0.443 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.443 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.443 | |
| 3p3c | 3P3 | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.443 | |
| 3sl2 | ATP | Sensor histidine kinase WalK | / | 0.443 | |
| 3vp6 | HLD | Glutamate decarboxylase 1 | 4.1.1.15 | 0.443 | |
| 4acu | QN7 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.443 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.443 | |
| 4glx | 0XS | DNA ligase | 6.5.1.2 | 0.443 | |
| 4h9t | HL4 | Phosphotriesterase | / | 0.443 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.443 | |
| 4rr6 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.443 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.443 | |
| 4u0s | ADP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.443 | |
| 4x7u | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.443 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1u1g | BBB | Uridine phosphorylase | 2.4.2.3 | 0.442 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.442 | |
| 2nnq | T4B | Fatty acid-binding protein, adipocyte | / | 0.442 | |
| 2r0c | FAD | Putative FAD-monooxygenase | / | 0.442 | |
| 2vte | IK4 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.442 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 2x95 | X95 | Angiotensin-converting enzyme | 3.4.15.1 | 0.442 | |
| 3af0 | GDP | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 3bgs | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.442 | |
| 3ikt | NAD | Redox-sensing transcriptional repressor Rex | / | 0.442 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.442 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.442 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.442 | |
| 3tvq | DQH | Multifunctional cyclase-dehydratase-3-O-methyl transferase TcmN | 2.1.1 | 0.442 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.442 | |
| 4fhf | 0TT | Spore photoproduct lyase | / | 0.442 | |
| 4gll | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.442 | |
| 4tmc | FMN | Old yellow enzyme | / | 0.442 | |
| 4x7w | MVI | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.442 | |
| 4y1b | NAP | AntE | / | 0.442 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 1egd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.441 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.441 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.441 | |
| 1ni1 | 2C5 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.441 | |
| 1r2j | FAD | FkbI | / | 0.441 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.441 | |
| 1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.441 | |
| 3c1t | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.441 | |
| 3cxw | 7CP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.441 | |
| 3hdq | GDU | UDP-galactopyranose mutase | / | 0.441 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.441 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.441 | |
| 3rgz | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.441 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.441 | |
| 3ziu | LSS | Leucyl-tRNA synthetase | / | 0.441 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.441 | |
| 4dlc | UMP | Deoxyuridine triphosphatase, putative | / | 0.441 | |
| 4elf | 35I | Dihydrofolate reductase | / | 0.441 | |
| 4k37 | SAM | Anaerobic sulfatase-maturating enzyme | 1.8.98 | 0.441 | |
| 4xwt | U5P | Ribonuclease J | / | 0.441 | |
| 4yao | FMN | NADPH--cytochrome P450 reductase | / | 0.441 | |
| 4ycp | FMN | tRNA-dihydrouridine(16) synthase | / | 0.441 | |
| 4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.441 | |
| 1b8v | NAD | Malate dehydrogenase | / | 0.440 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 1gox | FMN | Peroxisomal (S)-2-hydroxy-acid oxidase | 1.1.3.15 | 0.440 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.440 | |
| 1j9z | FAD | NADPH--cytochrome P450 reductase | / | 0.440 | |
| 1l8a | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.440 | |
| 1n5q | TNC | ActVA 6 protein | / | 0.440 | |
| 1n95 | FTH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.440 | |
| 1tgv | 5UD | Uridine phosphorylase | 2.4.2.3 | 0.440 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.440 | |
| 2oc4 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 2pam | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.440 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.440 | |
| 2xpc | 051 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.440 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 2ydd | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.440 | |
| 3aw9 | GDU | NAD-dependent epimerase/dehydratase | / | 0.440 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.440 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.440 | |
| 3hgs | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.440 | |
| 3oet | NAD | Erythronate-4-phosphate dehydrogenase | / | 0.440 | |
| 3own | 3OX | Renin | 3.4.23.15 | 0.440 | |
| 3p80 | P80 | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 3p84 | FMN | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.440 | |
| 4aws | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.440 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.440 | |
| 4drm | 0MC | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.440 | |
| 4ejn | 0R4 | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.440 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.440 | |
| 4isu | IKM | Glutamate receptor 2 | / | 0.440 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.440 | |
| 4ocp | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.440 | |
| 4prx | ADP | DNA gyrase subunit B | / | 0.440 | |
| 4rp8 | ASC | Ascorbate-specific PTS system EIIC component | / | 0.440 | |
| 4xq6 | FMN | Dihydroorotate dehydrogenase (quinone) | / | 0.440 | |
| 4zow | CLM | Multidrug transporter MdfA | / | 0.440 |