sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3dd8 | 2C7 | Carbonic anhydrase 2 | 4.2.1.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3dd8 | 2C7 | Carbonic anhydrase 2 | 4.2.1.1 | 1.000 | |
| 3eft | 3BS | Carbonic anhydrase 2 | 4.2.1.1 | 0.775 | |
| 3s8x | E59 | Carbonic anhydrase 2 | 4.2.1.1 | 0.775 | |
| 3k2f | NKX | Carbonic anhydrase 2 | 4.2.1.1 | 0.752 | |
| 1i90 | INM | Carbonic anhydrase 2 | 4.2.1.1 | 0.750 | |
| 1if4 | FBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.744 | |
| 3sax | E50 | Carbonic anhydrase 2 | 4.2.1.1 | 0.741 | |
| 1zsb | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.739 | |
| 2eu3 | FF3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.739 | |
| 3b4f | TUO | Carbonic anhydrase 2 | 4.2.1.1 | 0.736 | |
| 3daz | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.736 | |
| 3mho | J43 | Carbonic anhydrase 2 | 4.2.1.1 | 0.735 | |
| 4ilx | 1EZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.729 | |
| 1bnv | AL7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.728 | |
| 3ml2 | SU0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.728 | |
| 4kni | E1E | Carbonic anhydrase 2 | 4.2.1.1 | 0.728 | |
| 1i9n | IOA | Carbonic anhydrase 2 | 4.2.1.1 | 0.727 | |
| 3oim | VZ5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.725 | |
| 4itp | 1GD | Carbonic anhydrase 2 | 4.2.1.1 | 0.725 | |
| 1g1d | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.722 | |
| 1if6 | FBU | Carbonic anhydrase 2 | 4.2.1.1 | 0.718 | |
| 2weh | FB1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.716 | |
| 1bnm | AL8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.715 | |
| 3sbh | E65 | Carbonic anhydrase 2 | 4.2.1.1 | 0.715 | |
| 3m2n | J74 | Carbonic anhydrase 2 | 4.2.1.1 | 0.714 | |
| 1kwr | SG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.713 | |
| 1i91 | INQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.712 | |
| 1a42 | BZU | Carbonic anhydrase 2 | 4.2.1.1 | 0.708 | |
| 1okm | SAB | Carbonic anhydrase 2 | 4.2.1.1 | 0.707 | |
| 2h15 | B19 | Carbonic anhydrase 2 | 4.2.1.1 | 0.706 | |
| 3ffp | LC1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.705 | |
| 3m67 | E36 | Carbonic anhydrase 2 | 4.2.1.1 | 0.705 | |
| 3m98 | E02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.705 | |
| 3n3j | WWV | Carbonic anhydrase 2 | 4.2.1.1 | 0.704 | |
| 1i8z | INL | Carbonic anhydrase 2 | 4.2.1.1 | 0.703 | |
| 3bet | CTF | Carbonic anhydrase 2 | 4.2.1.1 | 0.700 | |
| 3po6 | DT9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.698 | |
| 1bnn | AL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.694 | |
| 2weg | FBV | Carbonic anhydrase 2 | 4.2.1.1 | 0.694 | |
| 3mmf | D9H | Carbonic anhydrase 2 | 4.2.1.1 | 0.690 | |
| 1g52 | F2B | Carbonic anhydrase 2 | 4.2.1.1 | 0.689 | |
| 3mna | DWH | Carbonic anhydrase 2 | 4.2.1.1 | 0.689 | |
| 1bn4 | AL9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.687 | |
| 3sbi | E90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.687 | |
| 1bn1 | AL5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.681 | |
| 1bnw | TPD | Carbonic anhydrase 2 | 4.2.1.1 | 0.681 | |
| 3oik | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.680 | |
| 3m40 | J45 | Carbonic anhydrase 2 | 4.2.1.1 | 0.672 | |
| 1bnt | AL2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.671 | |
| 1g4j | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.669 | |
| 1oq5 | CEL | Carbonic anhydrase 2 | 4.2.1.1 | 0.669 | |
| 3igp | DT7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.669 | |
| 4ito | MPX | Carbonic anhydrase 2 | 4.2.1.1 | 0.669 | |
| 3n0n | P9B | Carbonic anhydrase 2 | 4.2.1.1 | 0.665 | |
| 3n4b | WWZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.664 | |
| 3d9z | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.662 | |
| 3mzc | S6I | Carbonic anhydrase 2 | 4.2.1.1 | 0.660 | |
| 3oy0 | OY0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.660 | |
| 3mhl | J71 | Carbonic anhydrase 2 | 4.2.1.1 | 0.658 | |
| 2wej | FB2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.657 | |
| 3qyk | IE2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.656 | |
| 3t84 | SG6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.655 | |
| 1cil | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.654 | |
| 1kwq | SG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.654 | |
| 4iwz | 1GO | Carbonic anhydrase 2 | 4.2.1.1 | 0.654 | |
| 1cny | EG3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.651 | |
| 4bf6 | X0Q | Carbonic anhydrase 2 | 4.2.1.1 | 0.651 | |
| 3oys | OYS | Carbonic anhydrase 2 | 4.2.1.1 | 0.650 | |
| 3hku | TOR | Carbonic anhydrase 2 | 4.2.1.1 | 0.647 | |
| 3mhi | J90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.647 | |
| 3m96 | E38 | Carbonic anhydrase 2 | 4.2.1.1 | 0.646 | |
| 3s9t | E49 | Carbonic anhydrase 2 | 4.2.1.1 | 0.645 | |
| 3m5e | JDR | Carbonic anhydrase 2 | 4.2.1.1 | 0.643 | |
| 3n2p | AYX | Carbonic anhydrase 2 | 4.2.1.1 | 0.642 | |
| 4knj | E1F | Carbonic anhydrase 2 | 4.2.1.1 | 0.642 | |
| 4mo8 | 2VQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.642 | |
| 3nb5 | R21 | Carbonic anhydrase 2 | 4.2.1.1 | 0.641 | |
| 1ttm | 667 | Carbonic anhydrase 2 | 4.2.1.1 | 0.640 | |
| 2h4n | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.635 | |
| 3v2j | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.632 | |
| 3d8w | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.630 | |
| 3f4x | KLT | Carbonic anhydrase 2 | 4.2.1.1 | 0.630 | |
| 3ni5 | C1H | Carbonic anhydrase 2 | 4.2.1.1 | 0.630 | |
| 4kp8 | E1G | Carbonic anhydrase 12 | 4.2.1.1 | 0.629 | |
| 3m2y | BE0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.628 | |
| 4n16 | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.627 | |
| 3myq | E27 | Carbonic anhydrase 2 | 4.2.1.1 | 0.625 | |
| 3p5l | IT5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.624 | |
| 3dcs | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.623 | |
| 3kig | DA4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.622 | |
| 5flt | VJJ | Carbonic anhydrase 2 | 4.2.1.1 | 0.621 | |
| 2weo | FBW | Carbonic anhydrase 2 | 4.2.1.1 | 0.619 | |
| 2q1q | OSP | Carbonic anhydrase 2 | 4.2.1.1 | 0.618 | |
| 1bn3 | AL6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.616 | |
| 1g54 | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.615 | |
| 1cnw | EG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.614 | |
| 2pow | I7C | Carbonic anhydrase 2 | 4.2.1.1 | 0.611 | |
| 4k13 | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.611 | |
| 2x7t | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.609 | |
| 3bl1 | BL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.609 | |
| 3mdz | EZL | Carbonic anhydrase 7 | 4.2.1.1 | 0.607 | |
| 3oyq | OYQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.607 | |
| 1if5 | FBT | Carbonic anhydrase 2 | 4.2.1.1 | 0.605 | |
| 3t82 | SG4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.605 | |
| 1g4o | BSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.603 | |
| 3dd0 | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.601 | |
| 1okn | STB | Carbonic anhydrase 2 | 4.2.1.1 | 0.600 | |
| 3dcc | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.597 | |
| 4bf1 | 9FK | Carbonic anhydrase 2 | 4.2.1.1 | 0.596 | |
| 2wd2 | MS5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.595 | |
| 4kap | 1QV | Carbonic anhydrase 2 | 4.2.1.1 | 0.590 | |
| 3znc | BZ1 | Carbonic anhydrase 4 | 4.2.1.1 | 0.589 | |
| 4pxx | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.588 | |
| 3dc3 | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.587 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.587 | |
| 1xpz | 4TZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.586 | |
| 1g45 | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.584 | |
| 4ht2 | V50 | Carbonic anhydrase 12 | 4.2.1.1 | 0.584 | |
| 1if8 | SBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.583 | |
| 1okl | MNS | Carbonic anhydrase 2 | 4.2.1.1 | 0.582 | |
| 3t85 | SG7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.582 | |
| 1jd0 | AZM | Carbonic anhydrase 12 | 4.2.1.1 | 0.581 | |
| 1bnq | AL4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.576 | |
| 4dz7 | D02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.574 | |
| 2x7u | WZA | Carbonic anhydrase 2 | 4.2.1.1 | 0.573 | |
| 1bnu | AL3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.572 | |
| 1eou | SMS | Carbonic anhydrase 2 | 4.2.1.1 | 0.569 | |
| 1xq0 | 4TR | Carbonic anhydrase 2 | 4.2.1.1 | 0.566 | |
| 3dcw | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.561 | |
| 4lu3 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.554 | |
| 4x5s | AZM | Carbonic anhydrase (Carbonate dehydratase) | / | 0.554 | |
| 3l14 | I7B | Carbonic anhydrase 2 | 4.2.1.1 | 0.553 | |
| 3fw3 | ETS | Carbonic anhydrase 4 | 4.2.1.1 | 0.551 | |
| 1i9q | IOF | Carbonic anhydrase 2 | 4.2.1.1 | 0.550 | |
| 1yda | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.547 | |
| 4kp5 | E1F | Carbonic anhydrase 12 | 4.2.1.1 | 0.546 | |
| 4m2r | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.545 | |
| 3f7u | AG4 | Carbonic anhydrase 4 | 4.2.1.1 | 0.543 | |
| 1i9p | IOE | Carbonic anhydrase 2 | 4.2.1.1 | 0.540 | |
| 4m2v | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.535 | |
| 1cnx | EG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.531 | |
| 4uov | AZM | Carbonate dehydratase | / | 0.530 | |
| 3f7b | AG5 | Carbonic anhydrase 4 | 4.2.1.1 | 0.528 | |
| 3mhc | ARZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.525 | |
| 1if7 | SBR | Carbonic anhydrase 2 | 4.2.1.1 | 0.523 | |
| 4knm | E1E | Carbonic anhydrase 13 | 4.2.1.1 | 0.520 | |
| 3lxe | TOR | Carbonic anhydrase 1 | 4.2.1.1 | 0.517 | |
| 4hu1 | V13 | Carbonic anhydrase 13 | 4.2.1.1 | 0.511 | |
| 1rj6 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.506 | |
| 3rz8 | RZ8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.506 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.504 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.504 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.501 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.501 | |
| 1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.500 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.500 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.500 | |
| 4knn | E1F | Carbonic anhydrase 13 | 4.2.1.1 | 0.499 | |
| 4k0z | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.497 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.496 | |
| 4rp8 | ASC | Ascorbate-specific PTS system EIIC component | / | 0.496 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.495 | |
| 4ca8 | 3ES | Angiotensin-converting enzyme | 3.4.15.1 | 0.494 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.492 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.491 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.491 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.490 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.490 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.489 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.488 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.487 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.487 | |
| 4h9t | HL4 | Phosphotriesterase | / | 0.486 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.485 | |
| 4w5k | PLP | Aspartate aminotransferase, mitochondrial | / | 0.485 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.484 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.483 | |
| 1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.482 | |
| 4k0t | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.482 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.482 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.481 | |
| 1n95 | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.481 | |
| 1n95 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.481 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.481 | |
| 2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.481 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.481 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.481 | |
| 4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.481 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.481 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.480 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.480 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.480 | |
| 4c49 | HCY | Corticosteroid-binding globulin | / | 0.480 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.480 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.479 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.479 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.478 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.478 | |
| 1bl4 | AP1 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.477 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.477 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.477 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.476 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.476 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.476 | |
| 2dg4 | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.475 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.475 | |
| 3dbu | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.475 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.474 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.474 | |
| 4b64 | NAP | L-ornithine N(5)-monooxygenase | / | 0.474 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.474 | |
| 4iae | 1DX | Alr2278 protein | / | 0.474 | |
| 5fl4 | 9FK | Carbonic anhydrase 9 | 4.2.1.1 | 0.474 | |
| 1j37 | X8Z | Angiotensin-converting enzyme | 3.4.15.1 | 0.473 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.472 | |
| 2ab8 | MTP | Adenosine kinase | 2.7.1.20 | 0.472 | |
| 2bn4 | FMN | NADPH--cytochrome P450 reductase | / | 0.472 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.472 | |
| 2i7p | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.472 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.472 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.472 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.472 | |
| 1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.471 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.471 | |
| 3g70 | A5T | Renin | 3.4.23.15 | 0.471 | |
| 3ksq | Z96 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.471 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.471 | |
| 5bnw | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.471 | |
| 5c4f | UPG | Histo-blood group ABO system transferase | / | 0.471 | |
| 6std | MS2 | Scytalone dehydratase | 4.2.1.94 | 0.471 | |
| 1nsg | RAD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.470 | |
| 1nsg | RAD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.470 | |
| 1wxj | IPL | Tryptophan synthase alpha chain | / | 0.470 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.470 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.470 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.470 | |
| 2jbs | FMN | p-hydroxyphenylacetate 3-hydroxylase, oxygenase component | / | 0.470 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.470 | |
| 4lzw | THM | Uridine phosphorylase | / | 0.470 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.469 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.469 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.469 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.469 | |
| 3ruh | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.469 | |
| 1n95 | FTH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.468 | |
| 2fap | RAD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.468 | |
| 2fap | RAD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.468 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.468 | |
| 3p80 | P80 | Pentaerythritol tetranitrate reductase | / | 0.468 | |
| 3vil | SA0 | Beta-glucosidase | / | 0.468 | |
| 3ziu | LSS | Leucyl-tRNA synthetase | / | 0.468 | |
| 4aws | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.468 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.468 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.467 | |
| 1tow | CRZ | Fatty acid-binding protein, adipocyte | / | 0.467 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.467 | |
| 2xiq | 5AD | Methylmalonyl-CoA mutase, mitochondrial | / | 0.467 | |
| 4eb5 | PLP | Cysteine desulfurase IscS 2 | / | 0.467 | |
| 4iah | 1DX | Alr2278 protein | / | 0.467 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.466 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.466 | |
| 2lfo | GCH | Fatty acid-binding protein, liver | / | 0.466 | |
| 2xug | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.466 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.466 | |
| 3fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.466 | |
| 3fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.466 | |
| 3gjw | GJW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.466 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.466 | |
| 3uzz | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.466 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.466 | |
| 4gdd | NAI | UDP-galactopyranose mutase | / | 0.466 | |
| 4m0f | 1YK | Acetylcholinesterase | 3.1.1.7 | 0.466 | |
| 1kfb | IGP | Tryptophan synthase alpha chain | / | 0.465 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.465 | |
| 3b1d | PLS | BetaC-S lyase | / | 0.465 | |
| 3cav | CI2 | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.465 | |
| 3myt | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.465 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.465 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.465 | |
| 2aba | STR | Pentaerythritol tetranitrate reductase | / | 0.464 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.464 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.464 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.464 | |
| 3dzk | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.464 | |
| 3rvh | HQ2 | Lysine-specific demethylase 4A | 1.14.11 | 0.464 | |
| 3tr0 | 5GP | Guanylate kinase | / | 0.464 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.464 | |
| 1ld8 | U49 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.463 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.463 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.463 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.463 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.463 | |
| 3w3n | RX8 | Toll-like receptor 8 | / | 0.463 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.463 | |
| 4fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.463 | |
| 4fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.463 | |
| 4gd4 | 0WS | Lysine-specific demethylase 4A | 1.14.11 | 0.463 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.463 | |
| 4rls | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.463 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.462 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.462 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.462 | |
| 1tl7 | FOK | Adenylate cyclase type 2 | / | 0.462 | |
| 1tl7 | FOK | Adenylate cyclase type 5 | / | 0.462 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.462 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.462 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.462 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.462 | |
| 2xuq | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.462 | |
| 2yoz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.462 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.462 | |
| 1a9z | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.461 | |
| 1jcq | 739 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.461 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 2ejz | SAH | Diphthine synthase | / | 0.461 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.461 | |
| 3lu1 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.461 | |
| 3qj0 | QI3 | Botulinum neurotoxin type A | 3.4.24.69 | 0.461 | |
| 4b63 | NAP | L-ornithine N(5)-monooxygenase | / | 0.461 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.461 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.461 | |
| 4nv1 | 4TG | Formyl transferase | / | 0.461 | |
| 1cnf | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.460 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.460 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.460 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.460 | |
| 1vot | HUP | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.460 | |
| 2x94 | X94 | Angiotensin-converting enzyme | 3.4.15.1 | 0.460 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.460 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.460 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 4wdg | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.460 | |
| 1cjv | FOK | Adenylate cyclase type 2 | / | 0.459 | |
| 1cjv | FOK | Adenylate cyclase type 5 | / | 0.459 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.459 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.459 | |
| 1yqs | BSA | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.459 | |
| 2acl | L05 | Oxysterols receptor LXR-alpha | / | 0.459 | |
| 2d3a | ADP | Glutamine synthetase root isozyme 3 | 6.3.1.2 | 0.459 | |
| 3w6h | AZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.459 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.459 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.459 | |
| 4jic | FMN | GTN Reductase | / | 0.459 | |
| 1ni1 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.458 | |
| 1u1g | BBB | Uridine phosphorylase | 2.4.2.3 | 0.458 | |
| 2hs8 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.458 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.458 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.458 | |
| 2r59 | PH0 | Leukotriene A-4 hydrolase | 3.3.2.6 | 0.458 | |
| 2xje | U5P | Cytosolic purine 5'-nucleotidase | 3.1.3.5 | 0.458 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.458 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.458 | |
| 4e2d | FMN | Dehydrogenase | / | 0.458 | |
| 4g8j | THM | Uridine phosphorylase | / | 0.458 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.457 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.457 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.457 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.457 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.457 | |
| 2xuf | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.457 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 3hdy | GDU | UDP-galactopyranose mutase | / | 0.457 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.457 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.456 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.456 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.456 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.456 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.456 | |
| 2hs6 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.456 | |
| 2onm | ADP | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.456 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.456 | |
| 3own | 3OX | Renin | 3.4.23.15 | 0.456 | |
| 3q7f | ED2 | Uncharacterized protein | / | 0.456 | |
| 3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.456 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.456 | |
| 3zvm | ADP | Bifunctional polynucleotide phosphatase/kinase | 2.7.1.78 | 0.456 | |
| 1kw9 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.455 | |
| 1q45 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.455 | |
| 1xva | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.455 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.455 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.455 | |
| 2ydb | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.455 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.455 | |
| 3rgz | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.455 | |
| 4c71 | 7RD | 3-oxoacyl-ACP synthase | / | 0.455 | |
| 4i9n | 1E5 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.455 | |
| 4l0q | NAD | Alcohol dehydrogenase class-3 | / | 0.455 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.455 | |
| 5hwo | HMG | Hydroxymethylglutaryl-CoA synthase | / | 0.455 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.454 | |
| 2a5h | SAM | L-lysine 2,3-aminomutase | 5.4.3.2 | 0.454 | |
| 2lba | CHO | Fatty acid binding protein 6 | / | 0.454 | |
| 3e33 | ED7 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.454 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 4drm | 0MC | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.454 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.453 | |
| 1sa4 | JAN | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.453 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.453 | |
| 2fvl | NAP | Aldo-keto reductase family 1 member C4 | 1.1.1.225 | 0.453 | |
| 2gou | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.453 | |
| 2hdj | NDP | Aldo-keto reductase family 1 member C2 | / | 0.453 | |
| 2std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.453 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.453 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 3bl7 | DD1 | m7GpppX diphosphatase | 3.6.1.59 | 0.453 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 3qeo | LLT | Deoxycytidine kinase | 2.7.1.74 | 0.453 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.453 | |
| 4fgc | PQ0 | NADPH-dependent 7-cyano-7-deazaguanine reductase | 1.7.1.13 | 0.453 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.453 | |
| 4x7u | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.453 | |
| 4xr9 | NAD | CalS8 | / | 0.453 | |
| 5a01 | 12V | O-glycosyltransferase | / | 0.453 | |
| 5c1g | GDU | Histo-blood group ABO system transferase | / | 0.453 | |
| 1o1s | 1NH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.452 | |
| 1odj | GMP | Purine nucleoside phosphorylase | / | 0.452 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.452 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.452 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.452 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.452 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.452 | |
| 2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.452 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3fr2 | 8CA | Fatty acid-binding protein, adipocyte | / | 0.452 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.452 | |
| 4a6r | TA8 | Probable aminotransferase | / | 0.452 | |
| 4dbc | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.452 | |
| 4ejv | LCL | Transcriptional regulator TcaR | / | 0.452 | |
| 4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.452 | |
| 4n1g | CEI | Obelin | / | 0.452 | |
| 4twr | NAD | NAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase | / | 0.452 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.451 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.451 | |
| 1tco | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.451 | |
| 1tco | FK5 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | 3.1.3.16 | 0.451 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.451 | |
| 3bj8 | COA | Diamine acetyltransferase 1 | / | 0.451 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 3hdq | GDU | UDP-galactopyranose mutase | / | 0.451 | |
| 3v2u | ATP | Protein GAL3 | / | 0.451 | |
| 3zht | TD9 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.451 | |
| 4j4n | D44 | Peptidylprolyl isomerase | / | 0.451 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1ld7 | U66 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.450 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.450 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.450 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.450 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 3mkn | DNB | Pyrimidine-specific ribonucleoside hydrolase RihB | / | 0.450 | |
| 3uzz | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.450 | |
| 4jay | NAP | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.450 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.450 | |
| 4r81 | FMN | Predicted NADH dehydrogenase | / | 0.450 | |
| 4yp6 | NAP | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.450 | |
| 5fd8 | A5A | Putative carboxypeptidase yocD | / | 0.450 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.449 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.449 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.449 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.449 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.449 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.449 | |
| 3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.449 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.449 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 1q20 | PLO | Sulfotransferase family cytosolic 2B member 1 | 2.8.2.2 | 0.448 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 2zvc | SAH | Precorrin-3 C17-methyltransferase | / | 0.448 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.448 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.448 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.448 | |
| 3ru7 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.448 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.448 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 4yco | FMN | tRNA-dihydrouridine(16) synthase | / | 0.448 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.448 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.447 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.447 | |
| 1kw0 | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.447 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.447 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.447 | |
| 1w76 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.447 | |
| 2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.447 | |
| 2b3v | ACO | Diamine acetyltransferase 1 | / | 0.447 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.447 | |
| 2gby | BRN | HTH-type transcriptional regulator QacR | / | 0.447 | |
| 2r8v | ACO | Amino-acid acetyltransferase | / | 0.447 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 2wqp | WQP | Polysialic acid capsule biosynthesis protein SiaC | / | 0.447 | |
| 2ym2 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.447 | |
| 3fr4 | F8A | Fatty acid-binding protein, adipocyte | / | 0.447 | |
| 3lnc | 5GP | Guanylate kinase | / | 0.447 | |
| 3lqs | PSZ | D-alanine aminotransferase | 2.6.1.21 | 0.447 | |
| 3r7k | FDA | Probable acyl CoA dehydrogenase | / | 0.447 | |
| 4wdf | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.447 | |
| 1bxs | NAD | Retinal dehydrogenase 1 | 1.2.1.36 | 0.446 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.446 | |
| 1k4m | NAD | Nicotinate-nucleotide adenylyltransferase | 2.7.7.18 | 0.446 | |
| 1toj | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.446 | |
| 1w4l | GL8 | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 2ed4 | NAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.446 | |
| 2vat | COA | Acetyl-CoA--deacetylcephalosporin C acetyltransferase | 2.3.1.175 | 0.446 | |
| 2xda | JPS | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.446 | |
| 2ym1 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.446 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.446 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.446 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.446 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.445 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.445 | |
| 2gyu | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 2xtn | GTP | GTPase IMAP family member 2 | / | 0.445 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 2z1q | FAD | Acyl-CoA dehydrogenase | / | 0.445 | |
| 3gka | FMN | N-ethylmaleimide reductase | / | 0.445 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.445 | |
| 4bis | 8HQ | Lysine-specific demethylase 4A | 1.14.11 | 0.445 | |
| 4bqz | GNP | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.445 | |
| 4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.445 | |
| 4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 4yer | ADP | Antibiotic ABC transporter, ATP-binding protein, putative | / | 0.445 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.444 | |
| 1c7o | PPG | Hemolysin | / | 0.444 | |
| 1fkf | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.444 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.444 | |
| 2x91 | LPR | Angiotensin-converting enzyme | 3.4.15.1 | 0.444 | |
| 2xuj | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.444 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.444 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.444 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 1ivs | VAA | Valine--tRNA ligase | 6.1.1.9 | 0.443 | |
| 1kp3 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.443 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.443 | |
| 2hps | CTZ | Ca2+-triggered coelenterazine-binding protein 1 | / | 0.443 | |
| 2i7n | ACO | Pantothenate kinase 1 | 2.7.1.33 | 0.443 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.443 | |
| 2vn1 | FK5 | Peptidylprolyl isomerase | / | 0.443 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.443 | |
| 3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.443 | |
| 3c3e | GDP | 2-phospho-L-lactate transferase | / | 0.443 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.443 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.443 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.443 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.443 | |
| 4c13 | UML | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase | / | 0.443 | |
| 4lut | DCS | Alanine racemase | / | 0.443 | |
| 4u7w | NDP | MxaA | / | 0.443 | |
| 4xba | 5GP | Aprataxin-like protein | 3 | 0.443 | |
| 5kgp | ACO | Predicted acetyltransferase | / | 0.443 | |
| 1a5b | IGP | Tryptophan synthase alpha chain | / | 0.442 | |
| 1akb | PPD | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.442 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 1fkb | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.442 | |
| 1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.442 | |
| 1til | ATP | Anti-sigma F factor | / | 0.442 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.442 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.442 | |
| 2dxd | ANP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.442 | |
| 2gev | COK | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 2idk | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.442 | |
| 2rdn | 1PL | 1-deoxypentalenic acid 11-beta-hydroxylase | 1.14.11.35 | 0.442 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3anm | SYD | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.442 | |
| 3faz | NOS | Purine nucleoside phosphorylase | / | 0.442 | |
| 3hxd | BD7 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.442 | |
| 3maa | FKP | Adenylate cyclase type 2 | / | 0.442 | |
| 3maa | FKP | Adenylate cyclase type 5 | / | 0.442 | |
| 3mau | EXT | Putative sphingosine-1-phosphate lyase | / | 0.442 | |
| 3o5r | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.442 | |
| 3ruc | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.442 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.442 | |
| 3tvq | DQH | Multifunctional cyclase-dehydratase-3-O-methyl transferase TcmN | 2.1.1 | 0.442 | |
| 3zs7 | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.442 | |
| 4dri | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.442 | |
| 4dri | RAP | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.442 | |
| 4ehy | ADP | Tetraacyldisaccharide 4'-kinase | / | 0.442 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 1fap | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.441 | |
| 1fap | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.441 | |
| 1gax | VAA | Valine--tRNA ligase | 6.1.1.9 | 0.441 | |
| 1h36 | R88 | Squalene--hopene cyclase | 4.2.1.129 | 0.441 | |
| 1jum | BER | HTH-type transcriptional regulator QacR | / | 0.441 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.441 | |
| 1wze | NAD | Malate dehydrogenase | / | 0.441 | |
| 2a92 | NAI | L-lactate dehydrogenase | / | 0.441 | |
| 2a9z | 26A | Adenosine kinase | 2.7.1.20 | 0.441 | |
| 2bf4 | FAD | NADPH--cytochrome P450 reductase | / | 0.441 | |
| 2q85 | 973 | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.441 | |
| 2uuo | LK3 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.441 | |
| 2vd7 | PD2 | Lysine-specific demethylase 4A | 1.14.11 | 0.441 | |
| 3a0t | ADP | Sensor histidine kinase | / | 0.441 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.441 | |
| 3k1w | BFX | Renin | 3.4.23.15 | 0.441 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3m2u | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.441 | |
| 3pdq | KC6 | Lysine-specific demethylase 4A | 1.14.11 | 0.441 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3ru9 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.441 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.441 | |
| 4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.441 | |
| 4rvf | TYD | D-mycarose 3-C-methyltransferase | / | 0.441 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.441 | |
| 5c1d | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.441 | |
| 5doz | NDP | JamJ | / | 0.441 | |
| 1cju | FOK | Adenylate cyclase type 2 | / | 0.440 | |
| 1cju | FOK | Adenylate cyclase type 5 | / | 0.440 | |
| 1dtp | APU | Diphtheria toxin | / | 0.440 | |
| 1gpn | HUB | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 1gtr | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.440 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 1l7x | 700 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.440 | |
| 1nhk | CMP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.440 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.440 | |
| 1w19 | T5P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.440 | |
| 1w34 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.440 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.440 | |
| 2aj4 | ANP | Galactokinase | 2.7.1.6 | 0.440 | |
| 2anb | 5GP | Guanylate kinase | 2.7.4.8 | 0.440 | |
| 2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.440 | |
| 2iml | FMN | Uncharacterized protein | / | 0.440 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.440 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.440 | |
| 3b9x | NOS | Pyrimidine-specific ribonucleoside hydrolase RihB | 3.2.2.8 | 0.440 | |
| 3bgs | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.440 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.440 | |
| 3kjg | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.440 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 4gcm | NAP | Thioredoxin reductase | 1.8.1.9 | 0.440 | |
| 4nv1 | 0FX | Formyl transferase | / | 0.440 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.440 | |
| 4x7z | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.440 | |
| 5er0 | FAD | Uncharacterized NAD(FAD)-dependent dehydrogenase | / | 0.440 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.440 | |
| 5jy1 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.440 |