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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2gtbAZPOrf1ab polyprotein

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
2gtbAZPOrf1ab polyprotein/1.000
2a5kAZPReplicase polyprotein 1ab3.4.220.642
1xe55FEPlasmepsin-23.4.23.390.521
2qiqCYVReplicase polyprotein 1ab/0.519
4ke11R6Beta-secretase 13.4.23.460.513
3qgf46FGenome polyprotein2.7.7.480.508
4frkDWDBeta-secretase 13.4.23.460.502
2g1y5IGRenin3.4.23.150.500
2hydADPPutative multidrug export ATP-binding/permease protein SAV18663.6.30.500
2g1r3IGRenin3.4.23.150.495
3v3m0ENReplicase polyprotein 1a3.4.19.120.495
2ejkSAHDiphthine synthase/0.493
3qt62P0Mevalonate diphosphate decarboxylase/0.491
1g63FMNEpidermin decarboxylase4.1.10.490
1w6hTITPlasmepsin-23.4.23.390.490
2a5hSAML-lysine 2,3-aminomutase5.4.3.20.489
3vydVYDRenin3.4.23.150.489
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.488
4bfzZVZPantothenate kinase2.7.1.330.488
3ixp834Ecdysone receptor/0.487
3phiNDPShikimate dehydrogenase (NADP(+))/0.486
4eu9COASuccinyl-CoA:acetate CoA-transferase/0.486
4fxy0W2Neurolysin, mitochondrial3.4.24.160.486
1kp2ATPArgininosuccinate synthase6.3.4.50.484
2huqSAHDiphthine synthase/0.483
4acxS8ZBeta-secretase 13.4.23.460.483
2dsgSAHDiphthine synthase/0.482
3hl0NADMaleylacetate reductase/0.482
3vqsJT1Genome polyprotein/0.482
2op9WR1Orf1ab polyprotein/0.481
1t2cNAIL-lactate dehydrogenase1.1.1.270.480
2ek4SAHDiphthine synthase/0.480
2q7oIMHPurine nucleoside phosphorylase2.4.2.10.480
4a862ANMajor pollen allergen Bet v 1-A/0.480
2g1s4IGRenin3.4.23.150.479
4c4oNADSADH/0.479
1psa0ZLPepsin A3.4.23.10.478
2ed3SAHDiphthine synthase/0.478
2g20L1ARenin3.4.23.150.478
3uozFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.477
4q71FADBifunctional protein PutA/0.477
1a5bIGPTryptophan synthase alpha chain/0.476
1rneC60Renin3.4.23.150.476
2il2LIXRenin3.4.23.150.476
2z3lPHE_ARG_TYR_LEU_GLYLeucyl/phenylalanyl-tRNA--protein transferase2.3.2.60.476
4a8v2ANMajor pollen allergen Bet v 1-J/0.476
2dxvSAHDiphthine synthase/0.475
2ikuLIYRenin3.4.23.150.475
1fy7COAHistone acetyltransferase ESA1/0.474
1lbcCYZGlutamate receptor 2/0.474
1kbo340NAD(P)H dehydrogenase [quinone] 11.6.5.20.473
1kkq471Peroxisome proliferator-activated receptor alpha/0.473
2a94AP0L-lactate dehydrogenase1.1.1.270.473
2uxpCLMHTH-type transcriptional regulator TtgR/0.473
4g7gVFVLanosterol 14-alpha-demethylase/0.472
5dp2NAPCurF/0.472
1bil0IURenin3.4.23.150.471
1g1aNADdTDP-glucose 4,6-dehydratase/0.471
2e8qSAHDiphthine synthase/0.471
3pqbVGPPutative oxidoreductase/0.471
4a87NARMajor pollen allergen Bet v 1-A/0.471
4azy7F3Beta-secretase 13.4.23.460.471
4eywL0RCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.471
1beuIPLTryptophan synthase alpha chain/0.470
1x1aSAMC-20 methyltransferase/0.470
2g226IGRenin3.4.23.150.470
2he5NDPAldo-keto reductase family 1 member C211.1.10.470
2pncCLUPrimary amine oxidase, liver isozyme/0.470
3phjDHKShikimate dehydrogenase (NADP(+))/0.470
3qv1NADGlyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic1.2.1.130.470
4uymVOR14-alpha sterol demethylase Cyp51B/0.470
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.469
1mjbACOHistone acetyltransferase ESA1/0.469
1xe65FPPlasmepsin-23.4.23.390.469
2eniSAHDiphthine synthase/0.469
2oapANPType II secretion system protein (GspE-2)/0.469
3sp9IL2Peroxisome proliferator-activated receptor delta/0.469
4b7754MBeta-secretase 13.4.23.460.469
1kp3ATPArgininosuccinate synthase6.3.4.50.468
1yb5NAPQuinone oxidoreductase1.6.5.50.468
1zxmANPDNA topoisomerase 2-alpha5.99.1.30.468
2ek7SAHDiphthine synthase/0.468
2npiATPmRNA cleavage and polyadenylation factor CLP1/0.468
3b04OOPIsopentenyl-diphosphate delta-isomerase/0.468
3lpkZ76Beta-secretase 13.4.23.460.468
4djaFAD(6-4) photolyase/0.468
2c20NADUDP-glucose 4-epimerase/0.467
2e17SAHDiphthine synthase/0.467
2eldSAHDiphthine synthase/0.467
2g1o2IGRenin3.4.23.150.467
3g70A5TRenin3.4.23.150.467
3gwfNAPCyclohexanone monooxygenase/0.467
4a81DXCMajor pollen allergen Bet v 1-A/0.467
4lutDCSAlanine racemase/0.467
2pchSAHDiphthine synthase/0.466
2ya3J7V5'-AMP-activated protein kinase subunit gamma-1/0.466
3kb1ADPIron-sulfur cluster carrier protein/0.466
3rueNADUDP-N-acetylglucosamine 4-epimerase/0.466
4a83DXCMajor pollen allergen Bet v 1-A/0.466
1yqxNAPSinapyl alcohol dehydrogenase/0.465
2cmjNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.465
2emuSAHDiphthine synthase/0.465
2eudGCQRibonucleoside-diphosphate reductase large chain 11.17.4.10.465
2p6lSAHDiphthine synthase/0.465
2v16C47Renin3.4.23.150.465
2zatNAPDehydrogenase/reductase SDR family member 41.1.1.1840.465
3iqiASN_GLU_ASN_ILECysteine synthase2.5.1.470.465
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.465
3u9eCOALmo1369 protein/0.465
3vyfVYFRenin3.4.23.150.465
3wleNAD(R)-specific carbonyl reductase/0.465
4bfxZVXPantothenate kinase2.7.1.330.465
4m83ERYOleandomycin glycosyltransferase2.4.10.465
2eglSAHDiphthine synthase/0.464
2el0SAHDiphthine synthase/0.464
2emrSAHDiphthine synthase/0.464
2ovhAS0Progesterone receptor/0.464
4acuQN7Beta-secretase 13.4.23.460.464
4eagATP5'-AMP-activated protein kinase subunit gamma-1/0.464
4nbwNADShort-chain dehydrogenase/reductase SDR/0.464
5einNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.464
1l2tATPUncharacterized ABC transporter ATP-binding protein MJ0796/0.463
2dv7SAHDiphthine synthase/0.463
2ed4NAD4-hydroxyphenylacetate 3-monooxygenase reductase component1.5.1.360.463
2g1n1IGRenin3.4.23.150.463
2pb4SAHDiphthine synthase/0.463
3bc3OPTCathepsin L13.4.22.150.463
4a802ANMajor pollen allergen Bet v 1-A/0.463
4em4FADCoenzyme A disulfide reductase/0.463
4loi1YCStimulator of interferon genes protein/0.463
1i7gAZ2Peroxisome proliferator-activated receptor alpha/0.462
1o9bNAIQuinate/shikimate dehydrogenase/0.462
1qorNDPQuinone oxidoreductase 1/0.462
1w0kADPATP synthase subunit alpha, mitochondrial/0.462
1w0kADPATP synthase subunit beta, mitochondrial3.6.3.140.462
1wngSAHDiphthine synthase/0.462
2ejzSAHDiphthine synthase/0.462
2hk9NAPShikimate dehydrogenase (NADP(+))/0.462
2iyfERYOleandomycin glycosyltransferase2.4.10.462
2rlcCHDCholoylglycine hydrolase3.5.1.240.462
2y8lADP5'-AMP-activated protein kinase subunit gamma-1/0.462
2ym2FADPhenylacetone monooxygenase1.14.13.920.462
3duyAFJBeta-secretase 13.4.23.460.462
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.462
3lqfNADGalactitol dehydrogenase/0.462
3vkjFNRIsopentenyl-diphosphate delta-isomerase/0.462
3wqmB29Diterpene synthase3.1.7.80.462
3wrhCAMCamphor 5-monooxygenase1.14.15.10.462
4eakATP5'-AMP-activated protein kinase subunit gamma-1/0.462
4frjDWBBeta-secretase 13.4.23.460.462
1eioGCHGastrotropin/0.461
1q12ATPMaltose/maltodextrin import ATP-binding protein MalK/0.461
1tqf32PBeta-secretase 13.4.23.460.461
2huxSAHDiphthine synthase/0.461
3h3t16HCollagen type IV alpha-3-binding protein/0.461
3qwbNDPProbable quinone oxidoreductase1.6.5.50.461
3rfaSAMDual-specificity RNA methyltransferase RlmN/0.461
4ambDUDPutative glycosyl transferase/0.461
4j57FADThioredoxin reductase 21.8.1.90.461
1me6IVSPlasmepsin-23.4.23.390.460
1x27ASP_TYR_VAL_HIS_PTRTyrosine-protein kinase Lck2.7.10.20.460
2hunNAD336aa long hypothetical dTDP-glucose 4,6-dehydratase/0.460
2y1tDUDSPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS3.6.1.230.460
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.460
4cvmANPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.460
4g3jVNTLanosterol 14-alpha-demethylase/0.460
4gl4NAIAlcohol dehydrogenase class-3/0.460
4p9dTMPDeoxycytidylate deaminase/0.460
1fm4DXCMajor pollen allergen Bet v 1-L/0.459
3w6uNAP6-phosphogluconate dehydrogenase, NAD-binding protein/0.459
4dh60KNBeta-secretase 13.4.23.460.459
4djx0KQBeta-secretase 13.4.23.460.459
4g74FADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.459
4ycpFMNtRNA-dihydrouridine(16) synthase/0.459
2dv4SAHDiphthine synthase/0.458
2ed5SAHDiphthine synthase/0.458
2ewmNAD(S)-1-Phenylethanol dehydrogenase1.1.1.3110.458
2fzwNADAlcohol dehydrogenase class-31.1.1.10.458
2rqfJH3Hemolymph juvenile hormone binding protein/0.458
4k28NADShikimate dehydrogenase family protein/0.458
4lol1YEStimulator of interferon genes protein/0.458
5kwvANPPantothenate synthetase/0.458
1u3dFADCryptochrome-1/0.457
2fb2SAMGTP 3',8-cyclase4.1.99.180.457
2oz57XYUncharacterized protein/0.457
2pb5SAHDiphthine synthase/0.457
2po7CHDFerrochelatase, mitochondrial4.99.1.10.457
2vn0TDZCytochrome P450 2C8/0.457
3omuIBDHeat shock protein 83/0.457
3own3OWRenin3.4.23.150.457
4egbNADdTDP-glucose 4,6-dehydratase/0.457
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.456
1mjaCOAHistone acetyltransferase ESA1/0.456
1vi2NADQuinate/shikimate dehydrogenase/0.456
2dxwSAHDiphthine synthase/0.456
2dxxSAHDiphthine synthase/0.456
2gd6ACOProbable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase )/0.456
2hutSAHDiphthine synthase/0.456
2q5g1FAPeroxisome proliferator-activated receptor delta/0.456
2vkeTACTetracycline repressor protein class D/0.456
2vouFAD2,6-dihydroxypyridine 3-monooxygenase1.14.13.100.456
2yj4ATPCopper-transporting ATPase/0.456
3h3sH15Collagen type IV alpha-3-binding protein/0.456
3rbaCODPhosphopantetheine adenylyltransferase/0.456
4ipw1G7Mycocyclosin synthase1.14.21.90.456
4q72FADBifunctional protein PutA/0.456
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.456
2g21L1BRenin3.4.23.150.455
2g247IGRenin3.4.23.150.455
2vbpVB1Isopenicillin N synthase1.21.3.10.455
3eheNADUDP-glucose 4-epimerase (GalE-1)/0.455
3f03FMNPentaerythritol tetranitrate reductase/0.455
3pw8ACO1,2-phenylacetyl-CoA epoxidase, subunit A1.14.13.1490.455
3t3c017Gag-Pol polyprotein3.4.23.160.455
3tjzGNPADP-ribosylation factor 1/0.455
3tr05GPGuanylate kinase/0.455
4bftZVTPantothenate kinase2.7.1.330.455
4ead0NPThymidine phosphorylase2.4.2.40.455
4emtC2EStimulator of interferon genes protein/0.455
4h1e10JBeta-secretase 13.4.23.460.455
4k39SAMAnaerobic sulfatase-maturating enzyme1.8.980.455
1rfuADPPyridoxal kinase2.7.1.350.454
1tehNADAlcohol dehydrogenase class-31.1.1.10.454
2cvuCDPRibonucleoside-diphosphate reductase large chain 11.17.4.10.454
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.454
2yimMC4Probable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase )/0.454
2znpK55Peroxisome proliferator-activated receptor delta/0.454
3jv7NADSecondary alcohol dehydrogenase/0.454
4b68FADL-ornithine N(5)-monooxygenase/0.454
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.454
4bmsNAPAlclohol dehydrogenase/short-chain dehydrogenase/0.454
4h3f10OBeta-secretase 13.4.23.460.454
4ktoFADPutative isovaleryl-CoA dehydrogenase protein/0.454
4trnNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.454
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.453
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.453
1y0s331Peroxisome proliferator-activated receptor delta/0.453
2bjfDXCCholoylglycine hydrolase3.5.1.240.453
2gilGTPRas-related protein Rab-6A/0.453
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.453
2i4qUA4Renin3.4.23.150.453
2p83MR0Beta-secretase 13.4.23.460.453
2pr2DG1Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.453
2xuoTZ4Acetylcholinesterase3.1.1.70.453
3csoXNIGenome polyprotein2.7.7.480.453
3q43D66M1 family aminopeptidase3.4.110.453
3te5NAI5'-AMP-activated protein kinase subunit gamma/0.453
3vvpBNUUncharacterized protein/0.453
3zdfNADGlyceraldehyde-3-phosphate dehydrogenase/0.453
3zw9NADPeroxisomal bifunctional enzyme1.1.1.350.453
4dc0NDPPutative ketoacyl reductase1.3.10.453
4dfg0JVGag-Pol polyprotein3.4.23.160.453
4v2gITCTetracycline repressor protein class D/0.453
4x7wMVIMycinamicin III 3''-O-methyltransferase2.1.1.2370.453
1f8fNADBenzyl alcohol dehydrogenase/0.452
1pjcNADAlanine dehydrogenase/0.452
1t4cCOAFormyl-CoA:oxalate CoA-transferase/0.452
2d29FADAcyl-CoA dehydrogenase/0.452
2dv3SAHDiphthine synthase/0.452
2hr8SAHDiphthine synthase/0.452
2jcvNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.452
2owfSAHDiphthine synthase/0.452
2qbmCAMCamphor 5-monooxygenase1.14.15.10.452
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.452
3dr8ACOL-methionine sulfoximine/L-methionine sulfone acetyltransferase/0.452
3f3sNADLambda-crystallin homolog/0.452
3pgqGY3Acetyl-CoA carboxylase/0.452
3ukoNADAlcohol dehydrogenase class-3/0.452
3vucHHERenin3.4.23.150.452
4d89BXDBeta-secretase 13.4.23.460.452
4ejmNAPPutative zinc-binding dehydrogenase/0.452
4hmsFMNPhenazine biosynthesis protein PhzG1.40.452
4ho6UTPGlucose-1-phosphate thymidylyltransferase/0.452
5f8eSAHPossible transcriptional regulatory protein/0.452
1bk0ACVIsopenicillin N synthase1.21.3.10.451
1bxkNADdTDP-glucose 4,6-dehydratase 2/0.451
1cf3FADGlucose oxidase1.1.3.40.451
1mj9COAHistone acetyltransferase ESA1/0.451
1tytFADTrypanothione reductase1.8.1.120.451
2ifaFMNUncharacterized protein/0.451
2pcaSAHDiphthine synthase/0.451
2xc3RT8Steroid C26-monooxygenase1.14.13.1410.451
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
3d84NDPDihydrofolate reductase1.5.1.30.451
3oqfS51Renin3.4.23.150.451
4l0qNADAlcohol dehydrogenase class-3/0.451
4yp6NAPNicotinamide-nucleotide adenylyltransferase2.7.7.10.451
1k7fIAVTryptophan synthase alpha chain/0.450
1zeoC01Peroxisome proliferator-activated receptor gamma/0.450
2ahrNAPPyrroline-5-carboxylate reductase/0.450
2e07SAHDiphthine synthase/0.450
2e08SAHDiphthine synthase/0.450
2ejjSAHDiphthine synthase/0.450
2ggsNDPdTDP-4-dehydrorhamnose reductase/0.450
2j83BATUlilysin3.4.240.450
2pbwDOQGlutamate receptor ionotropic, kainate 1/0.450
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.450
2xy3DUPSPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS3.6.1.230.450
2zcvNDPQuinone oxidoreductase 21.6.5.20.450
2zvcSAHPrecorrin-3 C17-methyltransferase/0.450
3k5c0BIBeta-secretase 13.4.23.460.450
3own3OXRenin3.4.23.150.450
3p84FMNPentaerythritol tetranitrate reductase/0.450
3wv9FEGHmd co-occurring protein HcgE/0.450
4cqlNADEstradiol 17-beta-dehydrogenase 81.1.1.620.450
4ejvLCLTranscriptional regulator TcaR/0.450
4fj2NAP17beta-hydroxysteroid dehydrogenase/0.450
4gh5NADShort-chain dehydrogenase/reductase SDR/0.450
4i1c1BEBeta-secretase 13.4.23.460.450
4kvzSAHPtnL protein/0.450
5a9sNAPPutative dehydrogenase/0.450
1f20FADNitric oxide synthase, brain1.14.13.390.449
1xddAAYIntegrin alpha-L/0.449
2gv8NDPThiol-specific monooxygenase1.14.130.449
2hizLIJBeta-secretase 13.4.23.460.449
2q1uNADPutative nucleotide sugar epimerase/ dehydratase/0.449
3c35KAIGlutamate receptor ionotropic, kainate 1/0.449
3cobADPKinesin heavy chain-like protein/0.449
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.449
3ixj586Beta-secretase 13.4.23.460.449
3s1dZIRCytokinin dehydrogenase 11.5.99.120.449
3t3r9PLCytochrome P450 2A61.14.130.449
4a6bQG8Gag-Pol polyprotein3.4.23.160.449
4bfvZVVPantothenate kinase2.7.1.330.449
4fw8NAI3-oxoacyl-(Acyl-carrier-protein) reductase/0.449
4kgkGTPUncharacterized protein/0.449
4yqfGDPSeptin-9/0.449
5irnADPNucleotide binding oligomerization domain containing 2/0.449
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.448
1u3cFADCryptochrome-1/0.448
1vbiNADMalate/L-lactate dehydrogenase family protein/0.448
2a2cADPN-acetylgalactosamine kinase2.7.1.1570.448
2e8sSAHDiphthine synthase/0.448
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.448
2qw034Z4-chlorobenzoyl CoA ligase/0.448
2zrzFNRIsopentenyl-diphosphate delta-isomerase/0.448
2zsaADPPantothenate kinase2.7.1.330.448
3adaNADSubunit alpha of sarocosine oxidase/0.448
3bw2FMNPutative 2-nitropropane dioxygenase/0.448
3gbuATPUncharacterized sugar kinase PH14592.7.10.448
3ig6438Urokinase-type plasminogen activator3.4.21.730.448
3jqpA2PFerredoxin--NADP reductase, apicoplast/0.448
3qe2FMNNADPH--cytochrome P450 reductase/0.448
3wrjCAMCamphor 5-monooxygenase1.14.15.10.448
4bb3KKAIsopenicillin N synthase1.21.3.10.448
4dtiNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.448
4mlp2CXCryptochrome-2/0.448
4nd3NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.448
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.448
5jscFADPutative acyl-CoA dehydrogenase/0.448
1jedADPSulfate adenylyltransferase/0.447
1msmJE2Gag-Pol polyprotein3.4.23.160.447
1owmFADDeoxyribodipyrimidine photo-lyase4.1.99.30.447
2en5SAHDiphthine synthase/0.447
2fj1CTCTetracycline repressor protein class D/0.447
2fr0NDP6-deoxyerythronolide-B synthase EryA1, modules 1 and 2/0.447
2huvSAHDiphthine synthase/0.447
2iqgF2IBeta-secretase 13.4.23.460.447
2o4cNADErythronate-4-phosphate dehydrogenase/0.447
2uxoTACHTH-type transcriptional regulator TtgR/0.447
2xfyACXBeta-amylase3.2.1.20.447
2xlpFADPutative flavin-containing monooxygenase/0.447
2zbaZBATrichothecene 3-O-acetyltransferase/0.447
3ik6HCZGlutamate receptor 2/0.447
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.447
3oewNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.447
4a84DXCMajor pollen allergen Bet v 1-A/0.447
4b0532DBeta-secretase 13.4.23.460.447
4eudCOASuccinyl-CoA:acetate CoA-transferase/0.447
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.447
4tuvCPZCytochrome P450 1191.140.447
1bwsNDPGDP-L-fucose synthase/0.446
1drhNAPDihydrofolate reductase1.5.1.30.446
1i7pFADNADH-cytochrome b5 reductase 31.6.2.20.446
1ja0FADNADPH--cytochrome P450 reductase/0.446
2fy4COACholine O-acetyltransferase2.3.1.60.446
2p6iSAHDiphthine synthase/0.446
2qimZEAClass 10 plant pathogenesis-related protein/0.446
3a3gDLZLumazine protein/0.446
3g6zA7TRenin3.4.23.150.446
3isjA8DPantothenate synthetase6.3.2.10.446
3kxw1ZZSaframycin Mx1 synthetase B/0.446
3lpiZ74Beta-secretase 13.4.23.460.446
3o0o5ADVitamin B12-dependent ribonucleotide reductase/0.446
3p62FMNPentaerythritol tetranitrate reductase/0.446
3rsv3RSBeta-secretase 13.4.23.460.446
4mrm2BYGamma-aminobutyric acid type B receptor subunit 1/0.446
5eb5FAD(R)-mandelonitrile lyase 14.1.2.100.446
5eioNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.446
1e3eNAIAlcohol dehydrogenase 41.1.1.10.445
1qbqHFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.445
1qbqHFPProtein farnesyltransferase subunit beta2.5.1.580.445
1xl8152Peroxisomal carnitine O-octanoyltransferase2.3.1.1370.445
2a92NAIL-lactate dehydrogenase/0.445
2b8l5HABeta-secretase 13.4.23.460.445
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
2c27ACOMycothiol acetyltransferase2.3.1.1890.445
2g2zCOZMalonyl CoA-acyl carrier protein transacylase2.3.1.390.445
2ohvNHLGlutamate racemase/0.445
2ovmAS0Progesterone receptor/0.445
2uxhQUEHTH-type transcriptional regulator TtgR/0.445
2vijC44Beta-secretase 13.4.23.460.445
2w9hTOPDihydrofolate reductase1.5.1.30.445
2wpxACOOrf14/0.445
2x7hPFNProstaglandin reductase 310.445
2yoj8Y6Genome polyprotein2.7.7.480.445
3m2uCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.445
3zksWZVBeta-secretase 23.4.23.450.445
4b00I6XBeta-secretase 13.4.23.460.445
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.445
4k6fNAPPutative Acetoacetyl-CoA reductase/0.445
5cyoGDPSeptin-9/0.445
5er0FADUncharacterized NAD(FAD)-dependent dehydrogenase/0.445
1qoqIGPTryptophan synthase alpha chain/0.444
1udaUFGUDP-glucose 4-epimerase5.1.3.20.444
1y7lASN_LEU_ASN_ILECysteine synthase2.5.1.470.444
2a9y26AAdenosine kinase2.7.1.200.444
2abaSTRPentaerythritol tetranitrate reductase/0.444
2h21SAMRibulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic2.1.1.1270.444
2i7pACOPantothenate kinase 32.7.1.330.444
3ensENSCoagulation factor X3.4.21.60.444
3gw9VNILanosterol 14-alpha-demethylase/0.444
3hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.444
3p2oNADBifunctional protein FolD/0.444
3p67FMNPentaerythritol tetranitrate reductase/0.444
3to6LYS_CMCHistone acetyltransferase ESA1/0.444
3zoiM2WIsopenicillin N synthase1.21.3.10.444
4dptAGSMevalonate diphosphate decarboxylase/0.444
4eu8COASuccinyl-CoA:acetate CoA-transferase/0.444
4gddNAIUDP-galactopyranose mutase/0.444
4k8s1QTBeta-secretase 13.4.23.460.444
4m4922YL-lactate dehydrogenase A chain1.1.1.270.444
4zirANPEnergy-coupling factor transporter ATP-binding protein EcfA23.6.30.444
4zirANPEnergy-coupling factor transporter ATP-binding protein EcfA1/0.444
4zjuNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.444
1r6uTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.443
1yqdNAPSinapyl alcohol dehydrogenase/0.443
2dftADPShikimate kinase2.7.1.710.443
2nniMTKCytochrome P450 2C8/0.443
2wedPP6Penicillopepsin-13.4.23.200.443
2xlrFADPutative flavin-containing monooxygenase/0.443
3cic316Beta-secretase 13.4.23.460.443
3iqhTYR_ASP_ILECysteine synthase2.5.1.470.443
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.443
3mpjFADGlutaryl-CoA dehydrogenase1.3.99.320.443
3ru9NADUDP-N-acetylglucosamine 4-epimerase/0.443
3vswR31Renin3.4.23.150.443
3vv8B02Beta-secretase 13.4.23.460.443
4j531J4Serine/threonine-protein kinase PLK12.7.11.210.443
4kbyC2EStimulator of interferon genes protein/0.443
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.443
4oqyNDP(S)-imine reductase/0.443
4xq6FMNDihydroorotate dehydrogenase (quinone)/0.443
1orrNADCDP-paratose 2-epimerase/0.442
1qrpHH0Pepsin A-43.4.23.10.442
2fxfACODiamine acetyltransferase 1/0.442
2vbdV10Isopenicillin N synthase1.21.3.10.442
3b6zCO7Enoyl reductase LovC10.442
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
3i0pNADMalate dehydrogenase, putative/0.442
3ixk929Beta-secretase 13.4.23.460.442
3nxxNDPDihydrofolate reductase1.5.1.30.442
3slkNDPPolyketide synthase extender module 2/0.442
3t2kFADSulfide-quinone reductase/0.442
4gxs0YSGlutamate receptor 2/0.442
4h3j10WBeta-secretase 13.4.23.460.442
4lxa1YSBeta-secretase 13.4.23.460.442
4o1mNADEnoyl-acyl carrier reductase/0.442
4p53NAI2-epi-5-epi-valiolone synthase/0.442
1a9cGTPGTP cyclohydrolase 13.5.4.160.441
1bwlFMNNADPH dehydrogenase 11.6.99.10.441
1hb1OCVIsopenicillin N synthase1.21.3.10.441
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.441
1wvgAPRCDP-glucose 4,6-dehydratase4.2.1.450.441
2e0nSAHPrecorrin-2 C20-methyltransferase/0.441
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.441
2gjnFMNNitronate monooxygenase1.13.12.160.441
2iibC5PAlpha-2,3/2,6-sialyltransferase/sialidase/0.441
2wf4ZY4Beta-secretase 13.4.23.460.441
3a1cACPProbable copper-exporting P-type ATPase A3.6.3.540.441
3iaaTYDCalG2/0.441
3lu1NADUDP-N-acetylglucosamine 4-epimerase/0.441
3m2vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.441
3vsxR32Renin3.4.23.150.441
4b722FBBeta-secretase 13.4.23.460.441
4fizCUE17beta-hydroxysteroid dehydrogenase/0.441
4fn4NADShort chain dehydrogenase/0.441
4g6gFADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.441
4jb1FADUDP-N-acetylenolpyruvoylglucosamine reductase/0.441
4jnkZHKL-lactate dehydrogenase A chain1.1.1.270.441
4jq9FADDihydrolipoyl dehydrogenase/0.441
4qxp1YEStimulator of interferon genes protein/0.441
4xguADPPutative pachytene checkpoint protein 2/0.441
5c41ACPRibokinase/0.441
5idwNAPShort-chain dehydrogenase/reductase SDR/0.441
5k5zANPUncharacterized protein/0.441
6gsuGPSGlutathione S-transferase Mu 12.5.1.180.441
1h2bNAJNAD-dependent alcohol dehydrogenase/0.440
1i5eU5PUracil phosphoribosyltransferase/0.440
2b53D23Cyclin-dependent kinase 22.7.11.220.440
2g8yNADHydroxycarboxylate dehydrogenase B/0.440
2qd3CHDFerrochelatase, mitochondrial4.99.1.10.440
2xhd7T9Glutamate receptor 2/0.440
2yj5ATPCopper-transporting ATPase/0.440
2yylFAD4-hydroxyphenylacetate 3-monooxygenase oxygenase component1.14.14.90.440
2ztlNADD(-)-3-hydroxybutyrate dehydrogenase/0.440
3h2sNDPPutative NADH-flavin reductase/0.440
3imeBZ2Pantothenate synthetase6.3.2.10.440
3imgBZ2Pantothenate synthetase6.3.2.10.440
3rudNADUDP-N-acetylglucosamine 4-epimerase/0.440
3uovFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.440
4ddhMS0Pantothenate synthetase6.3.2.10.440
4gyzD5MTyrosyl-DNA phosphodiesterase 23.1.40.440
4ohvANPProtein clpf-1/0.440
4rvfTYDD-mycarose 3-C-methyltransferase/0.440
5dw60T1Succinyl-CoA:acetate CoA-transferase/0.440