sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1ghv | 120 | Prothrombin | 3.4.21.5 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1ghv | 120 | Prothrombin | 3.4.21.5 | 1.000 | |
| 1ypm | RA4 | Prothrombin | 3.4.21.5 | 0.688 | |
| 2zhq | 27U | Prothrombin | 3.4.21.5 | 0.687 | |
| 1d9i | 00P | Prothrombin | 3.4.21.5 | 0.683 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.675 | |
| 1o2g | 696 | Prothrombin | 3.4.21.5 | 0.665 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.662 | |
| 1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.658 | |
| 1ypj | UIB | Prothrombin | 3.4.21.5 | 0.656 | |
| 2zhf | 49U | Prothrombin | 3.4.21.5 | 0.655 | |
| 1c4v | IH2 | Prothrombin | 3.4.21.5 | 0.651 | |
| 1d3p | BT3 | Prothrombin | 3.4.21.5 | 0.648 | |
| 2cn0 | F25 | Prothrombin | 3.4.21.5 | 0.645 | |
| 2r2m | I50 | Prothrombin | 3.4.21.5 | 0.642 | |
| 2zhw | 12U | Prothrombin | 3.4.21.5 | 0.641 | |
| 2bvs | 2CE | Prothrombin | 3.4.21.5 | 0.640 | |
| 2jh5 | 895 | Prothrombin | 3.4.21.5 | 0.638 | |
| 3hat | GLY_VAL_ARG_RNG | Prothrombin | 3.4.21.5 | 0.634 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.632 | |
| 2v3o | I26 | Prothrombin | 3.4.21.5 | 0.628 | |
| 2zda | 32U | Prothrombin | 3.4.21.5 | 0.628 | |
| 1zgi | 382 | Prothrombin | 3.4.21.5 | 0.627 | |
| 2anm | CDO | Prothrombin | 3.4.21.5 | 0.627 | |
| 2jh6 | 894 | Prothrombin | 3.4.21.5 | 0.627 | |
| 2v3h | I25 | Prothrombin | 3.4.21.5 | 0.626 | |
| 1oyt | FSN | Prothrombin | 3.4.21.5 | 0.625 | |
| 1ta6 | 177 | Prothrombin | 3.4.21.5 | 0.623 | |
| 3qwc | 98P | Prothrombin | 3.4.21.5 | 0.621 | |
| 1gj4 | 132 | Prothrombin | 3.4.21.5 | 0.620 | |
| 4ayy | 9MX | Prothrombin | 3.4.21.5 | 0.619 | |
| 1mu8 | CDB | Prothrombin | 3.4.21.5 | 0.618 | |
| 2zff | 53U | Prothrombin | 3.4.21.5 | 0.617 | |
| 2zfp | 19U | Prothrombin | 3.4.21.5 | 0.617 | |
| 2zgx | 29U | Prothrombin | 3.4.21.5 | 0.617 | |
| 2a2x | NA9 | Prothrombin | 3.4.21.5 | 0.614 | |
| 4bah | MEL | Prothrombin | 3.4.21.5 | 0.611 | |
| 1z71 | L17 | Prothrombin | 3.4.21.5 | 0.610 | |
| 2zfr | 46U | Prothrombin | 3.4.21.5 | 0.609 | |
| 2cf8 | ESH | Prothrombin | 3.4.21.5 | 0.608 | |
| 2zhe | 13U | Prothrombin | 3.4.21.5 | 0.607 | |
| 1o0d | 163 | Prothrombin | 3.4.21.5 | 0.606 | |
| 1sb1 | 165 | Prothrombin | 3.4.21.5 | 0.606 | |
| 2zgb | 21U | Prothrombin | 3.4.21.5 | 0.606 | |
| 3dhk | 23U | Prothrombin | 3.4.21.5 | 0.606 | |
| 2zdv | 37U | Prothrombin | 3.4.21.5 | 0.604 | |
| 2zi2 | 24U | Prothrombin | 3.4.21.5 | 0.603 | |
| 2znk | 31U | Prothrombin | 3.4.21.5 | 0.603 | |
| 4ax9 | N5N | Prothrombin | 3.4.21.5 | 0.601 | |
| 2zg0 | 50U | Prothrombin | 3.4.21.5 | 0.600 | |
| 1c4u | IH1 | Prothrombin | 3.4.21.5 | 0.599 | |
| 1t4u | 81A | Prothrombin | 3.4.21.5 | 0.599 | |
| 1o5g | CR9 | Prothrombin | 3.4.21.5 | 0.598 | |
| 1ypl | RA8 | Prothrombin | 3.4.21.5 | 0.597 | |
| 4ayv | 9MQ | Prothrombin | 3.4.21.5 | 0.597 | |
| 1ypg | UIR | Prothrombin | 3.4.21.5 | 0.596 | |
| 1ype | UIP | Prothrombin | 3.4.21.5 | 0.595 | |
| 2bdy | UNB | Prothrombin | 3.4.21.5 | 0.595 | |
| 3biu | 10U | Prothrombin | 3.4.21.5 | 0.594 | |
| 3eq0 | 2TS | Prothrombin | 3.4.21.5 | 0.594 | |
| 4lxb | 7R9 | Prothrombin | 3.4.21.5 | 0.594 | |
| 1d4p | BPP | Prothrombin | 3.4.21.5 | 0.593 | |
| 1t4v | 14A | Prothrombin | 3.4.21.5 | 0.593 | |
| 2jh0 | 701 | Prothrombin | 3.4.21.5 | 0.593 | |
| 1c5n | ESI | Prothrombin | 3.4.21.5 | 0.592 | |
| 2cf9 | 348 | Prothrombin | 3.4.21.5 | 0.592 | |
| 2pks | G44 | Prothrombin | 3.4.21.5 | 0.590 | |
| 1bcu | PRL | Prothrombin | 3.4.21.5 | 0.588 | |
| 1mu6 | CDA | Prothrombin | 3.4.21.5 | 0.587 | |
| 2zc9 | 22U | Prothrombin | 3.4.21.5 | 0.587 | |
| 1k22 | MEL | Prothrombin | 3.4.21.5 | 0.586 | |
| 1ta2 | 176 | Prothrombin | 3.4.21.5 | 0.586 | |
| 2zfq | 45U | Prothrombin | 3.4.21.5 | 0.585 | |
| 1afe | ALZ | Prothrombin | 3.4.21.5 | 0.582 | |
| 1c4y | IH3 | Prothrombin | 3.4.21.5 | 0.581 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.581 | |
| 2uuk | 897 | Prothrombin | 3.4.21.5 | 0.581 | |
| 1c1u | BAI | Prothrombin | 3.4.21.5 | 0.578 | |
| 3p17 | 99P | Prothrombin | 3.4.21.5 | 0.575 | |
| 1ypk | CCR | Prothrombin | 3.4.21.5 | 0.574 | |
| 4bao | MVF | Prothrombin | 3.4.21.5 | 0.573 | |
| 4loy | 6XS | Prothrombin | 3.4.21.5 | 0.573 | |
| 1vzq | SHY | Prothrombin | 3.4.21.5 | 0.572 | |
| 1mue | CDD | Prothrombin | 3.4.21.5 | 0.571 | |
| 1uvs | I11 | Prothrombin | 3.4.21.5 | 0.570 | |
| 3qto | 10P | Prothrombin | 3.4.21.5 | 0.568 | |
| 3biv | 11U | Prothrombin | 3.4.21.5 | 0.567 | |
| 2ziq | 26U | Prothrombin | 3.4.21.5 | 0.564 | |
| 2gde | SN3 | Prothrombin | 3.4.21.5 | 0.563 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.563 | |
| 1k21 | IGN | Prothrombin | 3.4.21.5 | 0.561 | |
| 1ny2 | ARG_PRO_PRO_GLY | Prothrombin | 3.4.21.5 | 0.560 | |
| 1w7g | MIU | Prothrombin | 3.4.21.5 | 0.560 | |
| 4az2 | 9MU | Prothrombin | 3.4.21.5 | 0.559 | |
| 1riw | OSC | Prothrombin | 3.4.21.5 | 0.558 | |
| 1zgv | 501 | Prothrombin | 3.4.21.5 | 0.554 | |
| 1ae8 | AZL | Prothrombin | 3.4.21.5 | 0.553 | |
| 3f68 | 91U | Prothrombin | 3.4.21.5 | 0.552 | |
| 1kts | C24 | Prothrombin | 3.4.21.5 | 0.551 | |
| 1zrb | 062 | Prothrombin | 3.4.21.5 | 0.551 | |
| 3dux | 64U | Prothrombin | 3.4.21.5 | 0.549 | |
| 3egk | M18 | Prothrombin | 3.4.21.5 | 0.549 | |
| 1nzq | 162 | Prothrombin | 3.4.21.5 | 0.546 | |
| 2zf0 | 51U | Prothrombin | 3.4.21.5 | 0.545 | |
| 3qtv | 06P | Prothrombin | 3.4.21.5 | 0.542 | |
| 4e7r | 0NW | Prothrombin | 3.4.21.5 | 0.542 | |
| 7kme | ACE_0BN_CHG_PRR | Prothrombin | 3.4.21.5 | 0.541 | |
| 2uuj | 896 | Prothrombin | 3.4.21.5 | 0.538 | |
| 4bak | M67 | Prothrombin | 3.4.21.5 | 0.536 | |
| 4hfp | 15U | Prothrombin | 3.4.21.5 | 0.534 | |
| 1jwt | BLI | Prothrombin | 3.4.21.5 | 0.531 | |
| 4rn6 | 15U | Prothrombin | 3.4.21.5 | 0.531 | |
| 1a4w | QWE | Prothrombin | 3.4.21.5 | 0.530 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.530 | |
| 4fuf | 8UP | Urokinase-type plasminogen activator | 3.4.21.73 | 0.528 | |
| 3c27 | DKK | Prothrombin | 3.4.21.5 | 0.525 | |
| 4ban | M6S | Prothrombin | 3.4.21.5 | 0.521 | |
| 4baq | M4Z | Prothrombin | 3.4.21.5 | 0.517 | |
| 4fue | 7UP | Urokinase-type plasminogen activator | 3.4.21.73 | 0.517 | |
| 4fui | UI3 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.512 | |
| 4bam | MM9 | Prothrombin | 3.4.21.5 | 0.511 | |
| 1sl3 | 170 | Prothrombin | 3.4.21.5 | 0.507 | |
| 1zsk | 421 | Coagulation factor XI | 3.4.21.27 | 0.505 | |
| 1owk | 303 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.503 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.501 | |
| 1wqv | PSM | Coagulation factor VII | 3.4.21.21 | 0.501 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.501 | |
| 3qdz | PRO_ALA_PRO_ARG | Prothrombin | 3.4.21.5 | 0.499 | |
| 4fub | 4UP | Urokinase-type plasminogen activator | 3.4.21.73 | 0.499 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.498 | |
| 1owe | 675 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.495 | |
| 2y5h | Y5H | Coagulation factor X | 3.4.21.6 | 0.495 | |
| 1c1w | BAH | Prothrombin | 3.4.21.5 | 0.492 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.491 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.491 | |
| 1f92 | UKP | Urokinase-type plasminogen activator | 3.4.21.73 | 0.489 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.489 | |
| 2bxt | C2D | Prothrombin | 3.4.21.5 | 0.487 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.487 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.486 | |
| 5f8f | SFG | Possible transcriptional regulatory protein | / | 0.486 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.484 | |
| 2jkv | NAP | 6-phosphogluconate dehydrogenase, decarboxylating | 1.1.1.44 | 0.484 | |
| 2zp0 | PI0 | Coagulation factor VII | 3.4.21.21 | 0.484 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.484 | |
| 4fud | 6UP | Urokinase-type plasminogen activator | 3.4.21.73 | 0.484 | |
| 5cmx | 0G6 | Prothrombin | 3.4.21.5 | 0.484 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.483 | |
| 1p44 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.482 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.482 | |
| 2g27 | 4LG | Renin | 3.4.23.15 | 0.481 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.481 | |
| 1owd | 497 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.479 | |
| 2qf2 | GDP | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | 4.1.1.32 | 0.479 | |
| 2y5g | FJD | Coagulation factor X | 3.4.21.6 | 0.479 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.479 | |
| 4jau | ADP | Sensor histidine kinase | / | 0.479 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.479 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.478 | |
| 2viv | VG2 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.478 | |
| 3v0x | ANH | Cationic trypsin | 3.4.21.4 | 0.478 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.478 | |
| 1i91 | INQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.477 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.477 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.477 | |
| 2g00 | 4QC | Coagulation factor X | 3.4.21.6 | 0.476 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.476 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.476 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.476 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.476 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.475 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.475 | |
| 2qs1 | UB1 | Glutamate receptor ionotropic, kainate 1 | / | 0.475 | |
| 1drf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.474 | |
| 1hf3 | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.474 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.474 | |
| 3fzn | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.474 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.474 | |
| 4bti | 7R9 | Coagulation factor X | 3.4.21.6 | 0.474 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.473 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.473 | |
| 3k1w | BFX | Renin | 3.4.23.15 | 0.473 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.473 | |
| 4m0f | 1YK | Acetylcholinesterase | 3.1.1.7 | 0.473 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.472 | |
| 1u6q | 745 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.472 | |
| 1uxk | NAD | Malate dehydrogenase | / | 0.472 | |
| 2c4f | GIL | Coagulation factor VII | 3.4.21.21 | 0.472 | |
| 2cbr | A80 | Cellular retinoic acid-binding protein 1 | / | 0.472 | |
| 3v4a | PK1 | Androgen receptor | / | 0.472 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.472 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.472 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.471 | |
| 1iqg | XME | Coagulation factor X | 3.4.21.6 | 0.471 | |
| 1vja | 7IN | Urokinase-type plasminogen activator | 3.4.21.73 | 0.471 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.471 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.471 | |
| 3zhu | TD8 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.471 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.470 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 3v2u | ATP | Protein GAL3 | / | 0.470 | |
| 1khe | GCP | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | 4.1.1.32 | 0.469 | |
| 1owi | 426 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.469 | |
| 1wtg | 3BP | Coagulation factor VII | 3.4.21.21 | 0.469 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.469 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.469 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.469 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.468 | |
| 2h21 | SAM | Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic | 2.1.1.127 | 0.468 | |
| 2q85 | 973 | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.468 | |
| 3sor | O58 | Coagulation factor XI | 3.4.21.27 | 0.468 | |
| 3wag | TYD | Glycosyltransferase | / | 0.468 | |
| 3zvm | ADP | Bifunctional polynucleotide phosphatase/kinase | 2.7.1.78 | 0.468 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.468 | |
| 1nfy | RTR | Coagulation factor X | 3.4.21.6 | 0.467 | |
| 2a2d | ANP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.467 | |
| 2ab8 | MTP | Adenosine kinase | 2.7.1.20 | 0.467 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.467 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.467 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.467 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.467 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.467 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.467 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 1p4a | PCP | Pur operon repressor | / | 0.466 | |
| 2lfo | GCH | Fatty acid-binding protein, liver | / | 0.466 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.466 | |
| 3own | 3OW | Renin | 3.4.23.15 | 0.466 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.465 | |
| 1ra3 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.465 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.465 | |
| 4usq | FAD | Pyridine nucleotide-disulfide oxidoreductase | / | 0.465 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.464 | |
| 2vf3 | GVS | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.464 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.464 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.464 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 4m5p | FMN | NADPH dehydrogenase | / | 0.464 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 4x7z | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.464 | |
| 4xqc | NAD | Homospermidine synthase | 2.5.1.44 | 0.464 | |
| 4xr9 | NAD | CalS8 | / | 0.464 | |
| 1iqe | XMB | Coagulation factor X | 3.4.21.6 | 0.463 | |
| 1sqt | UI3 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.463 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.463 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.463 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.463 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.463 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.463 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.462 | |
| 2fzm | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.462 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.462 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
| 4gyz | D5M | Tyrosyl-DNA phosphodiesterase 2 | 3.1.4 | 0.462 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.462 | |
| 5hyn | SAH | Histone-lysine N-methyltransferase EZH2 | 2.1.1.43 | 0.462 | |
| 1q12 | ATP | Maltose/maltodextrin import ATP-binding protein MalK | / | 0.461 | |
| 1uae | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.461 | |
| 2am2 | 2LG | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.461 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.461 | |
| 3vy2 | FMN | FMN-binding protein | / | 0.461 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.461 | |
| 4b63 | NAP | L-ornithine N(5)-monooxygenase | / | 0.461 | |
| 4twr | NAD | NAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase | / | 0.461 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 1nt1 | T76 | Prothrombin | 3.4.21.5 | 0.460 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.460 | |
| 2wky | IBC | Glutamate receptor ionotropic, kainate 1 | / | 0.460 | |
| 3wie | DN4 | Glucose 1-dehydrogenase | / | 0.460 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.460 | |
| 1cnf | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.459 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 1khb | GCP | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | 4.1.1.32 | 0.459 | |
| 1pwy | AC2 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.459 | |
| 2a1o | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 2aba | STR | Pentaerythritol tetranitrate reductase | / | 0.459 | |
| 2ag1 | TPP | Benzaldehyde lyase | / | 0.459 | |
| 2z52 | H23 | Geranylgeranyl pyrophosphate synthase | / | 0.459 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.459 | |
| 3x2f | NAI | Adenosylhomocysteinase | / | 0.459 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.459 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.458 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.458 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.458 | |
| 3ho2 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.458 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.458 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 1zdw | FLV | Prenyltransferase | / | 0.457 | |
| 2b9y | FAD | Putative aminooxidase | / | 0.457 | |
| 2c2a | ADP | Sensor histidine kinase | / | 0.457 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 2fbw | CBE | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | 1.3.5.1 | 0.457 | |
| 2fbw | CBE | Succinate dehydrogenase cytochrome b, large subunit | / | 0.457 | |
| 3g0y | P9A | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.457 | |
| 3juq | AJD | Phenazine biosynthesis protein A/B | / | 0.457 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.457 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.457 | |
| 1a8r | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.456 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.456 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.456 | |
| 2e83 | FMN | FMN-binding protein | / | 0.456 | |
| 2fs4 | PZ1 | Renin | 3.4.23.15 | 0.456 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.456 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.456 | |
| 4bri | UNP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.456 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.456 | |
| 4kap | 1QV | Carbonic anhydrase 2 | 4.2.1.1 | 0.456 | |
| 4o8a | FAD | Bifunctional protein PutA | 1.2.1.88 | 0.456 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.456 | |
| 1eii | RTL | Retinol-binding protein 2 | / | 0.455 | |
| 1og4 | NAI | T-cell ecto-ADP-ribosyltransferase 2 | / | 0.455 | |
| 1rkw | PNT | HTH-type transcriptional regulator QacR | / | 0.455 | |
| 1wxj | IPL | Tryptophan synthase alpha chain | / | 0.455 | |
| 2ejz | SAH | Diphthine synthase | / | 0.455 | |
| 2g21 | L1B | Renin | 3.4.23.15 | 0.455 | |
| 3g70 | A5T | Renin | 3.4.23.15 | 0.455 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.455 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.455 | |
| 3tif | ADP | Uncharacterized ABC transporter ATP-binding protein MJ0796 | / | 0.455 | |
| 3zhs | TD6 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.455 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.455 | |
| 4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.455 | |
| 4gv2 | 5ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.455 | |
| 4hdh | ATP | Genome polyprotein | 2.7.7.48 | 0.455 | |
| 4kgk | GTP | Uncharacterized protein | / | 0.455 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.454 | |
| 1h62 | ANB | Pentaerythritol tetranitrate reductase | / | 0.454 | |
| 1yqz | COA | Coenzyme A disulfide reductase | / | 0.454 | |
| 2c1z | U2F | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.454 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.454 | |
| 2cv2 | GSU | Glutamate--tRNA ligase | 6.1.1.17 | 0.454 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 2z7h | GG3 | Geranylgeranyl pyrophosphate synthase | / | 0.454 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.454 | |
| 3vqs | JT1 | Genome polyprotein | / | 0.454 | |
| 4eph | 0RK | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.454 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.454 | |
| 1hku | NAD | C-terminal-binding protein 1 | 1.1.1 | 0.453 | |
| 1l2t | ATP | Uncharacterized ABC transporter ATP-binding protein MJ0796 | / | 0.453 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1n75 | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.453 | |
| 1n77 | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.453 | |
| 1oo5 | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.453 | |
| 1pg3 | PRX | Acetyl-coenzyme A synthetase | / | 0.453 | |
| 1umk | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.453 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.453 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.453 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.453 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.453 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 3w8f | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.453 | |
| 3zid | GDP | Tubulin-like protein CetZ | / | 0.453 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.453 | |
| 1kqb | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.452 | |
| 1okl | MNS | Carbonic anhydrase 2 | 4.2.1.1 | 0.452 | |
| 1p0h | COA | Mycothiol acetyltransferase | 2.3.1.189 | 0.452 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.452 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.452 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 2j34 | GS6 | Coagulation factor X | 3.4.21.6 | 0.452 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 3a6q | FMN | FMN-binding protein | / | 0.452 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.452 | |
| 3kqe | LGM | Coagulation factor X | 3.4.21.6 | 0.452 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.452 | |
| 4cmf | PXG | Uncharacterized protein | / | 0.452 | |
| 4dmm | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.452 | |
| 4eb5 | PLP | Cysteine desulfurase IscS 2 | / | 0.452 | |
| 4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 1ege | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.451 | |
| 1gg5 | E09 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.451 | |
| 1gtr | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.451 | |
| 1h66 | RH1 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.451 | |
| 1iqh | XMF | Coagulation factor X | 3.4.21.6 | 0.451 | |
| 1m9m | 6NI | Nitric oxide synthase, endothelial | 1.14.13.39 | 0.451 | |
| 1u71 | MXA | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 2cji | GSK | Coagulation factor X | 3.4.21.6 | 0.451 | |
| 2fhj | H4Z | Formylmethanofuran--tetrahydromethanopterin formyltransferase | 2.3.1.101 | 0.451 | |
| 2gtb | AZP | Orf1ab polyprotein | / | 0.451 | |
| 2p8u | COA | Hydroxymethylglutaryl-CoA synthase, cytoplasmic | 2.3.3.10 | 0.451 | |
| 2rd2 | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.451 | |
| 3c35 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.451 | |
| 3ebl | GA4 | Gibberellin receptor GID1 | / | 0.451 | |
| 3gjw | GJW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.451 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.451 | |
| 4b1j | A1R | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.451 | |
| 4ctj | SAM | Genome polyprotein | / | 0.451 | |
| 4ewo | 996 | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 4h3j | 10W | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 4kto | FAD | Putative isovaleryl-CoA dehydrogenase protein | / | 0.451 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.451 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.451 | |
| 5f54 | TMP | Single-stranded-DNA-specific exonuclease | / | 0.451 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.450 | |
| 1n95 | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.450 | |
| 1n95 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.450 | |
| 2bkt | RPF | Renin | 3.4.23.15 | 0.450 | |
| 2e94 | 364 | Geranylgeranyl pyrophosphate synthase | / | 0.450 | |
| 2fr1 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.450 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.450 | |
| 2j4l | UTP | Uridylate kinase | 2.7.4.22 | 0.450 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 3e2s | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.450 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.450 | |
| 3t3q | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.450 | |
| 3tqc | ADP | Pantothenate kinase | / | 0.450 | |
| 4cf6 | CBD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 4emd | C5P | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.450 | |
| 4eua | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.450 | |
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 0.450 | |
| 4o2r | GDP | GTP-binding protein Rheb | / | 0.450 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.450 | |
| 4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.450 | |
| 1fxf | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.449 | |
| 1y7l | ASN_LEU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.449 | |
| 1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.449 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.449 | |
| 2vhq | ATP | NTPase P4 | / | 0.449 | |
| 2vuu | NAP | Nitrogen metabolite repression protein nmrA | / | 0.449 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3g1r | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.449 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.449 | |
| 3s7d | LEU_SER_LYS_LYS_MLZ | N-lysine methyltransferase SMYD2 | / | 0.449 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.449 | |
| 3tvq | DQH | Multifunctional cyclase-dehydratase-3-O-methyl transferase TcmN | 2.1.1 | 0.449 | |
| 3u2m | FAD | FAD-linked sulfhydryl oxidase ALR | 1.8.3.2 | 0.449 | |
| 3v49 | PK0 | Androgen receptor | / | 0.449 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.449 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.449 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.449 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 4bgi | I4I | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 4f7i | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.449 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.448 | |
| 1m9t | INE | Nitric oxide synthase, inducible | 1.14.13.39 | 0.448 | |
| 1ra8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.448 | |
| 1rx4 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1tww | HH2 | Dihydropteroate synthase | / | 0.448 | |
| 2abj | CBC | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.448 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.448 | |
| 2jt2 | C90 | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.448 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.448 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.448 | |
| 3lqs | PSZ | D-alanine aminotransferase | 2.6.1.21 | 0.448 | |
| 3mau | PLR | Putative sphingosine-1-phosphate lyase | / | 0.448 | |
| 3oad | LPO | Renin | 3.4.23.15 | 0.448 | |
| 3own | 3OX | Renin | 3.4.23.15 | 0.448 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.448 | |
| 3vsw | R31 | Renin | 3.4.23.15 | 0.448 | |
| 3w6u | NAP | 6-phosphogluconate dehydrogenase, NAD-binding protein | / | 0.448 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 4mlp | 2CX | Cryptochrome-2 | / | 0.448 | |
| 5ej9 | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.448 | |
| 5jhn | SAM | Histone-lysine N-methyltransferase EHMT2 | / | 0.448 | |
| 4zj8 | SUV | Orexin receptor type 1 | / | 0.448 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.447 | |
| 1lqd | CMI | Coagulation factor X | 3.4.21.6 | 0.447 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.447 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.447 | |
| 2xuf | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.447 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3jzd | NAD | Maleylacetate reductase | / | 0.447 | |
| 4fm8 | 0UQ | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 4jic | FMN | GTN Reductase | / | 0.447 | |
| 4u3j | GTP | Tubulin beta chain | / | 0.447 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.447 | |
| 4yao | FMN | NADPH--cytochrome P450 reductase | / | 0.447 | |
| 1dds | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 1hyg | NAP | L-2-hydroxycarboxylate dehydrogenase (NAD(P)(+)) | / | 0.446 | |
| 1jdz | FMB | Purine nucleoside phosphorylase | / | 0.446 | |
| 1ma0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.446 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.446 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 2aq7 | TL5 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.446 | |
| 2fhj | MFN | Formylmethanofuran--tetrahydromethanopterin formyltransferase | 2.3.1.101 | 0.446 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.446 | |
| 2ptf | FMN | Uncharacterized protein MTH_863 | / | 0.446 | |
| 2q2q | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.446 | |
| 2xys | SY9 | Soluble acetylcholine receptor | / | 0.446 | |
| 2yim | MC4 | Probable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase ) | / | 0.446 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3ens | ENS | Coagulation factor X | 3.4.21.6 | 0.446 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.446 | |
| 3hu1 | AGS | Transitional endoplasmic reticulum ATPase | 3.6.4.6 | 0.446 | |
| 4e0u | 0MV | Cyclic dipeptide N-prenyltransferase | / | 0.446 | |
| 4hyh | 1AM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 4mbs | MRV | C-C chemokine receptor type 5 | / | 0.446 | |
| 4ycp | FMN | tRNA-dihydrouridine(16) synthase | / | 0.446 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 1fx9 | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.445 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.445 | |
| 1qk3 | 5GP | Hypoxanthine-guanine-xanthine phosphoribosyltransferase | 2.4.2.22 | 0.445 | |
| 1rd7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1ty8 | ADP | Probable ADP-ribose 1''-phosphate phosphatase YML087W | 3.1.3.84 | 0.445 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.445 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.445 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.445 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.445 | |
| 2vyq | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.445 | |
| 3c36 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.445 | |
| 3hnz | PMN | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.445 | |
| 3kjg | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.445 | |
| 3mk6 | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.445 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.445 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.445 | |
| 4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4l0q | NAD | Alcohol dehydrogenase class-3 | / | 0.445 | |
| 4n9q | FMN | FMN-dependent NADH-azoreductase 1 | / | 0.445 | |
| 4p13 | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.445 | |
| 4tvb | NAD | Homospermidine synthase | 2.5.1.44 | 0.445 | |
| 4xjc | TTP | dCTP deaminase | / | 0.445 | |
| 5f8e | SAH | Possible transcriptional regulatory protein | / | 0.445 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 1xag | NAD | 3-dehydroquinate synthase | / | 0.444 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.444 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.444 | |
| 2ojg | 19A | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.444 | |
| 2xtn | GTP | GTPase IMAP family member 2 | / | 0.444 | |
| 3b2s | B2S | Trichothecene 3-O-acetyltransferase | / | 0.444 | |
| 3iqi | ASN_GLU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.444 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3r1r | ATP | Ribonucleoside-diphosphate reductase 1 subunit alpha | 1.17.4.1 | 0.444 | |
| 3s2v | 3HU | Glutamate receptor ionotropic, kainate 1 | / | 0.444 | |
| 3tjl | FMN | NADPH dehydrogenase | / | 0.444 | |
| 3w4y | FAD | Mitochondrial FAD-linked sulfhydryl oxidase ERV1 | 1.8.3.2 | 0.444 | |
| 4bj9 | UHB | Tankyrase-2 | 2.4.2.30 | 0.444 | |
| 4j1t | NAP | NAD(P) transhydrogenase subunit beta | / | 0.444 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.444 | |
| 4rpg | GDU | UDP-galactopyranose mutase | 5.4.99.9 | 0.444 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.444 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.444 | |
| 5c3a | URM | Histo-blood group ABO system transferase | / | 0.444 | |
| 5czy | SAM | Eukaryotic huntingtin interacting protein B | / | 0.444 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 1ddr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1lf2 | R37 | Plasmepsin-2 | 3.4.23.39 | 0.443 | |
| 1mcz | RMN | Benzoylformate decarboxylase | 4.1.1.7 | 0.443 | |
| 1mp0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.443 | |
| 1nm5 | NAP | NAD(P) transhydrogenase subunit beta | 1.6.1.2 | 0.443 | |
| 1ywg | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.443 | |
| 2ed4 | NAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.443 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.443 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.443 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.443 | |
| 2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.443 | |
| 3c34 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.443 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.443 | |
| 3eld | SFG | Methyltransferase | / | 0.443 | |
| 3ho9 | N3A | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.443 | |
| 3mel | TPP | Thiamin pyrophosphokinase family protein | / | 0.443 | |
| 3ppo | DCK | Glycine betaine/carnitine/choline-binding protein OpuCC | / | 0.443 | |
| 3q8h | AO9 | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | / | 0.443 | |
| 3vwe | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.443 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.443 | |
| 4h30 | 0ZD | Macrophage metalloelastase | 3.4.24.65 | 0.443 | |
| 4yco | FMN | tRNA-dihydrouridine(16) synthase | / | 0.443 | |
| 5dp2 | NAP | CurF | / | 0.443 | |
| 1cju | FOK | Adenylate cyclase type 2 | / | 0.442 | |
| 1cju | FOK | Adenylate cyclase type 5 | / | 0.442 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.442 | |
| 1ds7 | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.442 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.442 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.442 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.442 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1vgr | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.442 | |
| 1x1d | SAH | C-20 methyltransferase | / | 0.442 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.442 | |
| 2b35 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.442 | |
| 2vce | U2F | UDP-glycosyltransferase 72B1 | / | 0.442 | |
| 2x7t | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.442 | |
| 2xb8 | XNW | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.442 | |
| 2y99 | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.442 | |
| 3iqg | ASN_TRP_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.442 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.442 | |
| 3to3 | ATP | Petrobactin biosynthesis protein AsbB | / | 0.442 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.442 | |
| 3zho | FMN | NAD(P)H dehydrogenase (quinone) | / | 0.442 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.442 | |
| 4c71 | 7RD | 3-oxoacyl-ACP synthase | / | 0.442 | |
| 4fgc | PQ0 | NADPH-dependent 7-cyano-7-deazaguanine reductase | 1.7.1.13 | 0.442 | |
| 4gl4 | NAI | Alcohol dehydrogenase class-3 | / | 0.442 | |
| 4ho6 | UTP | Glucose-1-phosphate thymidylyltransferase | / | 0.442 | |
| 4i1c | 1BE | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4jxx | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.442 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.442 | |
| 4wbd | ADP | Putative cysteine ligase BshC | / | 0.442 | |
| 5e5h | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.442 | |
| 1dgm | ADN | Adenosine kinase | 2.7.1.20 | 0.441 | |
| 1e0j | ANP | DNA primase/helicase | 2.7.7 | 0.441 | |
| 1icv | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.441 | |
| 1piw | NAP | NADP-dependent alcohol dehydrogenase 6 | 1.1.1.2 | 0.441 | |
| 1z7y | AA5 | Cysteine synthase 1 | 2.5.1.47 | 0.441 | |
| 2bn4 | FMN | NADPH--cytochrome P450 reductase | / | 0.441 | |
| 2e1m | FAD | L-glutamate oxidase | / | 0.441 | |
| 2fe4 | GDP | Ras-related protein Rab-6B | / | 0.441 | |
| 2v16 | C47 | Renin | 3.4.23.15 | 0.441 | |
| 2vqz | MGT | Polymerase basic protein 2 | / | 0.441 | |
| 2x3j | ATP | AcsD | / | 0.441 | |
| 3dcs | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.441 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.441 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.441 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 3qgf | 46F | Genome polyprotein | 2.7.7.48 | 0.441 | |
| 3u9y | 09L | Tankyrase-2 | 2.4.2.30 | 0.441 | |
| 4a6r | TA8 | Probable aminotransferase | / | 0.441 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.441 | |
| 4c6z | TLE | 3-oxoacyl-ACP synthase | / | 0.441 | |
| 4hhy | 15R | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.441 | |
| 4i8x | 6P3 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.441 | |
| 4jsr | 1NQ | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.441 | |
| 4u9y | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.441 | |
| 4x7w | MVI | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.441 | |
| 4xfj | ANP | Argininosuccinate synthase | / | 0.441 | |
| 5ein | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.441 | |
| 1coy | AND | Cholesterol oxidase | 1.1.3.6 | 0.440 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.440 | |
| 1kw9 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.440 | |
| 1lvu | 9PP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.440 | |
| 1ydt | IQB | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 1zid | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 2a5h | SAM | L-lysine 2,3-aminomutase | 5.4.3.2 | 0.440 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.440 | |
| 2iml | FMN | Uncharacterized protein | / | 0.440 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.440 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.440 | |
| 2r6g | ATP | Maltose/maltodextrin import ATP-binding protein MalK | / | 0.440 | |
| 2v2z | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.440 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 2vht | ATP | NTPase P4 | / | 0.440 | |
| 2vjm | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.440 | |
| 2z78 | H86 | Geranylgeranyl pyrophosphate synthase | / | 0.440 | |
| 3csc | ACO | Citrate synthase, mitochondrial | 2.3.3.1 | 0.440 | |
| 3dop | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.440 | |
| 3g72 | A6T | Renin | 3.4.23.15 | 0.440 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3kig | DA4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.440 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.440 | |
| 3t58 | FAD | Sulfhydryl oxidase 1 | 1.8.3.2 | 0.440 | |
| 3u5s | FAD | FAD-linked sulfhydryl oxidase ALR | 1.8.3.2 | 0.440 | |
| 3vil | SA0 | Beta-glucosidase | / | 0.440 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 4c73 | TLH | 3-oxoacyl-ACP synthase | / | 0.440 | |
| 4d03 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.440 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.440 | |
| 4e2d | FMN | Dehydrogenase | / | 0.440 | |
| 4fl0 | PLP | Aminotransferase ALD1, chloroplastic | 2.6.1 | 0.440 | |
| 4gm4 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.440 | |
| 4lcg | 1WM | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.440 | |
| 4n1g | CEI | Obelin | / | 0.440 | |
| 4px9 | ADP | ATP-dependent RNA helicase DDX3X | 3.6.4.13 | 0.440 | |
| 4rvg | TYD | D-mycarose 3-C-methyltransferase | / | 0.440 | |
| 4z38 | FMN | MlnA | / | 0.440 |