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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4n702HXSerine/threonine-protein kinase pim-12.7.11.1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4n702HXSerine/threonine-protein kinase pim-12.7.11.11.000
4n6z2HWSerine/threonine-protein kinase pim-12.7.11.10.714
1yi3LY2Serine/threonine-protein kinase pim-12.7.11.10.668
2j2iLY4Serine/threonine-protein kinase pim-12.7.11.10.652
3bgzVX3Serine/threonine-protein kinase pim-12.7.11.10.629
3c4eC4ESerine/threonine-protein kinase pim-12.7.11.10.627
1xwsBI1Serine/threonine-protein kinase pim-12.7.11.10.626
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.624
3uixQ17Serine/threonine-protein kinase pim-12.7.11.10.624
4k0y1OASerine/threonine-protein kinase pim-12.7.11.10.622
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.616
3vbq0F5Serine/threonine-protein kinase pim-12.7.11.10.611
4lm5Q17Serine/threonine-protein kinase pim-12.7.11.10.610
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.606
5dgzL20Serine/threonine-protein kinase pim-12.7.11.10.606
4a7cE46Serine/threonine-protein kinase pim-12.7.11.10.605
4lmuQUESerine/threonine-protein kinase pim-12.7.11.10.604
3r02UNMSerine/threonine-protein kinase pim-12.7.11.10.603
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.602
4dtk7LISerine/threonine-protein kinase pim-12.7.11.10.599
3dcv55ESerine/threonine-protein kinase pim-12.7.11.10.597
2bilBI1Serine/threonine-protein kinase pim-12.7.11.10.594
2xizXIZSerine/threonine-protein kinase pim-12.7.11.10.594
3jpv1DRSerine/threonine-protein kinase pim-12.7.11.10.594
4mbl26LSerine/threonine-protein kinase pim-12.7.11.10.592
2bikBI1Serine/threonine-protein kinase pim-12.7.11.10.585
1yi4ADNSerine/threonine-protein kinase pim-12.7.11.10.583
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.578
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.578
3bgpVX1Serine/threonine-protein kinase pim-12.7.11.10.577
3cxw7CPSerine/threonine-protein kinase pim-12.7.11.10.576
3umxQ18Serine/threonine-protein kinase pim-12.7.11.10.575
2c3iIYZSerine/threonine-protein kinase pim-12.7.11.10.573
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.572
4bznUGXSerine/threonine-protein kinase pim-12.7.11.10.571
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.568
4i41MIXSerine/threonine-protein kinase pim-12.7.11.10.565
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.560
3qf9NM8Serine/threonine-protein kinase pim-12.7.11.10.560
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.553
3jy0LYGSerine/threonine-protein kinase pim-12.7.11.10.553
2xj2985Serine/threonine-protein kinase pim-12.7.11.10.552
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.549
2xiyXIYSerine/threonine-protein kinase pim-12.7.11.10.545
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.545
4enyJ19Serine/threonine-protein kinase pim-12.7.11.10.538
3cy3JN5Serine/threonine-protein kinase pim-12.7.11.10.537
1xr1ANPSerine/threonine-protein kinase pim-12.7.11.10.535
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.531
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.528
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.525
3umw596Serine/threonine-protein kinase pim-12.7.11.10.523
4i22IREEpidermal growth factor receptor2.7.10.10.520
3mtfA3FActivin receptor type-12.7.11.300.519
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.519
3oom507Activin receptor type-12.7.11.300.518
4gw83RASerine/threonine-protein kinase pim-12.7.11.10.517
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.515
3a4pDFQHepatocyte growth factor receptor2.7.10.10.514
3mvl38PMitogen-activated protein kinase 14/0.514
4bchT7ZCyclin-dependent kinase 92.7.11.220.514
3vt7VDXVitamin D3 receptor/0.513
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.513
4c02TAKActivin receptor type-12.7.11.300.512
4gmy0X5Tyrosine-protein kinase JAK2/0.512
4jq8KJ8Epidermal growth factor receptor2.7.10.10.512
4yuqKS1Calmodulin-like domain protein kinase/0.512
4afjSJJGlycogen synthase kinase-3 beta2.7.11.260.510
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.509
4bgg844Activin receptor type-12.7.11.300.509
4othDRNSerine/threonine-protein kinase N1/0.509
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.508
2jedLG8Protein kinase C theta type2.7.11.130.507
4gg70J8Hepatocyte growth factor receptor2.7.10.10.507
3du8553Glycogen synthase kinase-3 beta2.7.11.260.506
4qmzB49Serine/threonine-protein kinase 242.7.11.10.506
4riyADPEpidermal growth factor receptor2.7.10.10.505
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.504
3uyt0CKCasein kinase I isoform delta2.7.11.10.503
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.500
3iw4LW4Protein kinase C alpha type2.7.11.130.500
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.500
4wboANWRhodopsin kinase/0.500
1zys199Serine/threonine-protein kinase Chk12.7.11.10.499
1xjdSTUProtein kinase C theta type2.7.11.130.498
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.498
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.497
4achKDIGlycogen synthase kinase-3 beta2.7.11.260.497
4ewqMWLMitogen-activated protein kinase 14/0.497
5auwQUEDeath-associated protein kinase 12.7.11.10.496
2ittAEEEpidermal growth factor receptor2.7.10.10.494
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.493
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.493
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.493
1bygSTUTyrosine-protein kinase CSK/0.492
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.492
4ib4ERM5-hydroxytryptamine receptor 2B/0.492
1og5SWFCytochrome P450 2C9/0.491
2h96893Mitogen-activated protein kinase 82.7.11.240.491
3nga3NGCasein kinase II subunit alpha2.7.11.10.491
4fob0USALK tyrosine kinase receptor2.7.10.10.491
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.490
3pjcPJCTyrosine-protein kinase JAK32.7.10.20.490
4gu610NFocal adhesion kinase 12.7.10.20.490
2iw84SPCyclin-dependent kinase 22.7.11.220.489
2j0m4STFocal adhesion kinase 12.7.10.20.489
2wihP48Cyclin-dependent kinase 22.7.11.220.489
3vs4VSFTyrosine-protein kinase HCK2.7.10.20.489
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.489
5cvhADPCasein kinase II subunit alpha2.7.11.10.489
1q1rFADPutidaredoxin reductase1.18.1.50.488
2excJNKMitogen-activated protein kinase 102.7.11.240.488
5cpbNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.488
3bqr4RBDeath-associated protein kinase 3/0.487
4b7tCWTGlycogen synthase kinase-3 beta2.7.11.260.487
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.486
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.486
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.486
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.486
3gc9B45Mitogen-activated protein kinase 112.7.11.240.486
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.486
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.486
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.486
4gii0X6Non-receptor tyrosine-protein kinase TYK22.7.10.20.486
1qxlFR8Adenosine deaminase3.5.4.40.485
2itpAEEEpidermal growth factor receptor2.7.10.10.485
4acdGR9Glycogen synthase kinase-3 beta2.7.11.260.485
4e730NRMitogen-activated protein kinase 82.7.11.240.485
2izrBRKCasein kinase I isoform gamma-32.7.11.10.483
3gubGUBDeath-associated protein kinase 12.7.11.10.483
3hllI45Mitogen-activated protein kinase 14/0.483
3r3b4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.483
3v3vMYUMitogen-activated protein kinase 82.7.11.240.483
3vryB43Tyrosine-protein kinase HCK2.7.10.20.483
3zze6XPHepatocyte growth factor receptor2.7.10.10.483
4dymIYZActivin receptor type-12.7.11.300.483
4grb0XGCasein kinase II subunit alpha2.7.11.10.483
4oacADPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.483
1oiyN41Cyclin-dependent kinase 22.7.11.220.482
3gxlQIGTGF-beta receptor type-12.7.11.300.482
4hvg19QTyrosine-protein kinase JAK32.7.10.20.482
1fpqSAMIsoliquiritigenin 2'-O-methyltransferase/0.481
1h1s4SPCyclin-dependent kinase 22.7.11.220.481
1oi9N20Cyclin-dependent kinase 22.7.11.220.481
2b365PPEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.481
2itqITQEpidermal growth factor receptor2.7.10.10.481
2xa4AZ5Tyrosine-protein kinase JAK2/0.481
2xikJ60Serine/threonine-protein kinase 252.7.11.10.481
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.481
1fp2HMOIsoflavone-7-O-methyltransferase 82.1.1.1500.480
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.480
2vuw5IDSerine/threonine-protein kinase haspin2.7.11.10.480
3kf7L9GMitogen-activated protein kinase 14/0.480
3vsoEK1Peroxisome proliferator-activated receptor gamma/0.480
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.480
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.479
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.479
3w1f1O5Dual specificity protein kinase TTK2.7.12.10.479
4ubsDIFPentalenic acid synthase1.14.15.110.479
1uu8BI13-phosphoinositide-dependent protein kinase 12.7.11.10.478
1wvxBD4Death-associated protein kinase 12.7.11.10.478
1zeoC01Peroxisome proliferator-activated receptor gamma/0.478
2b1pAIZMitogen-activated protein kinase 102.7.11.240.478
3dpd41APhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.478
3l1sZ92Glycogen synthase kinase-3 beta2.7.11.260.478
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.478
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.477
2j0k4STFocal adhesion kinase 12.7.10.20.477
3ncgBK1Calmodulin-domain protein kinase 1, putative/0.477
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.476
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.476
2q9fC3SCholesterol 24-hydroxylase/0.476
3ibqATPPyridoxal kinase/0.476
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.476
4jia1K3Tyrosine-protein kinase JAK2/0.476
4lopSB4Mitogen-activated protein kinase 14/0.476
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.476
2x1nX1NCyclin-dependent kinase 22.7.11.220.475
3eljGS7Mitogen-activated protein kinase 82.7.11.240.475
3f883HTGlycogen synthase kinase-3 beta2.7.11.260.475
2hog710Serine/threonine-protein kinase Chk12.7.11.10.474
3a60STURibosomal protein S6 kinase beta-12.7.11.10.474
3h18PMSEsterase/lipase/0.474
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.474
4hvh19RTyrosine-protein kinase JAK32.7.10.20.474
1m17AQ4Epidermal growth factor receptor2.7.10.10.473
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.473
2uxoTACHTH-type transcriptional regulator TtgR/0.473
3sd0TSKGlycogen synthase kinase-3 beta2.7.11.260.473
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.473
3zc5W9ZHepatocyte growth factor receptor2.7.10.10.473
4bi0Z0WDual specificity protein kinase TTK2.7.12.10.473
4fx360KCyclin-dependent kinase 22.7.11.220.473
4l455FIRibosomal protein S6 kinase beta-12.7.11.10.473
5e8xSTUTGF-beta receptor type-12.7.11.300.473
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.472
2uzlC94Cyclin-dependent kinase 22.7.11.220.472
3kn5ANPRibosomal protein S6 kinase alpha-52.7.11.10.472
3q9xEMOCasein kinase II subunit alpha2.7.11.10.472
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.472
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.472
4ezl0SEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.472
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.472
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.472
4hni16WCasein kinase I isoform epsilon2.7.11.10.472
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.472
5cu6ATPCasein kinase II subunit alpha2.7.11.10.472
2acxANPG protein-coupled receptor kinase 62.7.11.160.471
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.471
2ovhAS0Progesterone receptor/0.471
3eek53SUncharacterized protein/0.471
3q3b55EGlycogen synthase kinase-3 beta2.7.11.260.471
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.470
1umlFR4Adenosine deaminase3.5.4.40.470
1zx1CB1Ribosyldihydronicotinamide dehydrogenase [quinone]/0.470
2etm7PYFocal adhesion kinase 12.7.10.20.470
4f7l0SOCyclin-dependent kinase 82.7.11.220.470
4g170VNCasein kinase I isoform gamma-32.7.11.10.470
5amnDTQProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.470
5e8wSTUTGF-beta receptor type-12.7.11.300.470
1eh4IC1Casein kinase I homolog 12.7.11.10.469
1ouk084Mitogen-activated protein kinase 14/0.469
1pmn984Mitogen-activated protein kinase 102.7.11.240.469
2biyATP3-phosphoinositide-dependent protein kinase 12.7.11.10.469
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.469
2p33J07Mitogen-activated protein kinase 102.7.11.240.469
2zdt46CMitogen-activated protein kinase 102.7.11.240.469
3nd1SAHPrecorrin-6A synthase (Deacetylating)/0.469
3vt9YI4Vitamin D3 receptor/0.469
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.469
4nc3ERM5-hydroxytryptamine receptor 2B/0.469
3uzcT4EAdenosine receptor A2a/0.469
2bujSTUSerine/threonine-protein kinase 16/0.468
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.468
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.468
3fzpAGSProtein-tyrosine kinase 2-beta2.7.10.20.468
3zw3ZW3Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.468
4eok4SPCyclin-dependent kinase 22.7.11.220.468
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.468
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.468
4hvi19STyrosine-protein kinase JAK32.7.10.20.468
4jqeANPCasein kinase II subunit alpha2.7.11.10.468
4loqSB4Mitogen-activated protein kinase 14/0.468
5cshATPCasein kinase II subunit alpha2.7.11.10.468
1u54ACPActivated CDC42 kinase 1/0.467
2bdjHETProto-oncogene tyrosine-protein kinase Src2.7.10.20.467
2chlDKICasein kinase I isoform gamma-32.7.11.10.467
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.467
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.467
2vagV25Dual specificity protein kinase CLK12.7.12.10.467
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.467
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.467
2ydjYDJSerine/threonine-protein kinase Chk12.7.11.10.467
3dt1P40Mitogen-activated protein kinase 14/0.467
3gb2G3BGlycogen synthase kinase-3 beta2.7.11.260.467
3hztJ60Calmodulin-like domain protein kinase isoform 3/0.467
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.467
4nb6444Nuclear receptor ROR-gamma/0.467
4ux9ANPMitogen-activated protein kinase 82.7.11.240.467
1n4hREANuclear receptor ROR-beta/0.466
1oiuN76Cyclin-dependent kinase 22.7.11.220.466
2ay84TBAromatic-amino-acid aminotransferase2.6.1.570.466
2ckeIQUDeath-associated protein kinase 2/0.466
3pe2E1BCasein kinase II subunit alpha2.7.11.10.466
4c4g7RODual specificity protein kinase TTK2.7.12.10.466
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.466
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.466
4g1wG1WMitogen-activated protein kinase 82.7.11.240.466
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.466
4jq7KJQEpidermal growth factor receptor2.7.10.10.466
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.466
4neuQ1AReceptor-interacting serine/threonine-protein kinase 12.7.11.10.466
5auxKMPDeath-associated protein kinase 12.7.11.10.466
1d2sDHTSex hormone-binding globulin/0.465
1iidNHMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.465
1kkq471Peroxisome proliferator-activated receptor alpha/0.465
2i0ePDSProtein kinase C beta type2.7.11.130.465
2j0lANPFocal adhesion kinase 12.7.10.20.465
2qo9ANPEphrin type-A receptor 32.7.10.10.465
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.465
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.465
3fcoIIGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.465
3s1dZIRCytokinin dehydrogenase 11.5.99.120.465
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.465
4fyn0VETyrosine-protein kinase SYK2.7.10.20.465
4jboWPHAurora kinase A2.7.11.10.465
4q73FADBifunctional protein PutA/0.465
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.464
1x2hLPALipoate-protein ligase A6.3.1.200.464
2ay3MPPAromatic-amino-acid aminotransferase2.6.1.570.464
2c0tL3GTyrosine-protein kinase HCK2.7.10.20.464
2e9p77ASerine/threonine-protein kinase Chk12.7.11.10.464
2izsBRQCasein kinase I isoform gamma-32.7.11.10.464
2izuP01Casein kinase I isoform gamma-32.7.11.10.464
2pwlACPFibroblast growth factor receptor 2/0.464
2wedPP6Penicillopepsin-13.4.23.200.464
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.464
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.464
3ansS38Bifunctional epoxide hydrolase 23.3.2.100.464
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.464
3s7a684Dihydrofolate reductase1.5.1.30.464
3sheI85MAP kinase-activated protein kinase 32.7.11.10.464
3ttjJBIMitogen-activated protein kinase 102.7.11.240.464
4b99R4LMitogen-activated protein kinase 72.7.11.240.464
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.464
4dgnLU2Casein kinase II subunit alpha2.7.11.10.464
4fnyI3KALK tyrosine kinase receptor2.7.10.10.464
4tzk641Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.464
5av2KMPDeath-associated protein kinase 12.7.11.10.464
5av4GENDeath-associated protein kinase 12.7.11.10.464
1qnfFADDeoxyribodipyrimidine photo-lyase4.1.99.30.463
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.463
2znq401Peroxisome proliferator-activated receptor delta/0.463
3be9P04Casein kinase II subunit alpha2.7.11.10.463
3mpaSB2Mitogen-activated protein kinase 14/0.463
3th8TH9Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.463
3vf9477Tyrosine-protein kinase SYK2.7.10.20.463
4c4h7RODual specificity protein kinase TTK2.7.12.10.463
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.463
4hnf16WCasein kinase I isoform delta2.7.11.10.463
4iaq2GM5-hydroxytryptamine receptor 1B/0.463
4iarERM5-hydroxytryptamine receptor 1B/0.463
4j97ACPFibroblast growth factor receptor 2/0.463
4xuhSFIPeroxisome proliferator-activated receptor gamma/0.463
5cp4CAMCamphor 5-monooxygenase1.14.15.10.463
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.462
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.462
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.462
2ociTYCValacyclovir hydrolase3.10.462
3et7349Protein-tyrosine kinase 2-beta2.7.10.20.462
3irn1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.462
3sgx0FWDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.462
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.462
4kba1QMCasein kinase I isoform delta2.7.11.10.462
1aq1STUCyclin-dependent kinase 22.7.11.220.461
1r0eDFNGlycogen synthase kinase-3 beta2.7.11.260.461
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.461
3l9nL9NcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.461
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.461
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.461
4ezj0SCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.461
4wkqIREEpidermal growth factor receptor2.7.10.10.461
1e9hINRCyclin-dependent kinase 22.7.11.220.460
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.460
1rx8FOLDihydrofolate reductase1.5.1.30.460
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.460
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.460
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
2hmaSAMtRNA-specific 2-thiouridylase MnmA/0.460
2ojg19AMitogen-activated protein kinase 12.7.11.240.460
2py3ACPFibroblast growth factor receptor 2/0.460
3b7dCNIGlutamate receptor 2/0.460
3gwfFADCyclohexanone monooxygenase/0.460
3iqfE4MF420-dependent methylenetetrahydromethanopterin dehydrogenase1.5.98.10.460
3mdmFJZCholesterol 24-hydroxylase/0.460
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.460
3mtlFEFCyclin-dependent kinase 162.7.11.220.460
3s2a2NQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
3u4uLNHCasein kinase II subunit alpha2.7.11.10.460
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.460
4f630S7Fibroblast growth factor receptor 1/0.460
4ix6ADPUncharacterized protein/0.460
4kbk1QGCasein kinase I isoform delta2.7.11.10.460
5cccDDFDihydrofolate reductase1.5.1.30.460
1rx8NAPDihydrofolate reductase1.5.1.30.459
1yvj4STTyrosine-protein kinase JAK32.7.10.20.459
2wpa889Cyclin-dependent kinase 22.7.11.220.459
2zjwREFCasein kinase II subunit alpha2.7.11.10.459
3at4CCKCasein kinase II subunit alpha2.7.11.10.459
3f7z34OGlycogen synthase kinase-3 beta2.7.11.260.459
3l0lHC3Nuclear receptor ROR-gamma/0.459
3lcdBDYMacrophage colony-stimulating factor 1 receptor2.7.10.10.459
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.459
3vt8YI3Vitamin D3 receptor/0.459
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.459
4e4qRRHPeroxisome proliferator-activated receptor gamma/0.459
4fk3325Serine/threonine-protein kinase B-raf2.7.11.10.459
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.459
4kiq1RAMitogen-activated protein kinase 14/0.459
1u2gAPRNAD(P) transhydrogenase subunit alpha part 11.6.1.20.458
1uyrD1LAcetyl-CoA carboxylase/0.458
1v0pPVBCell division control protein 2 homolog2.7.11.220.458
2aqkNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.458
3gbk2PQPeroxisome proliferator-activated receptor gamma/0.458
3igoANPCalmodulin-domain protein kinase 1, putative/0.458
3l9lL9LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.458
3zrmZRMGlycogen synthase kinase-3 beta2.7.11.260.458
4c4f7CEDual specificity protein kinase TTK2.7.12.10.458
4dgo0JWCasein kinase II subunit alpha2.7.11.10.458
4gg50J3Hepatocyte growth factor receptor2.7.10.10.458
4m15ADPTyrosine-protein kinase ITK/TSK2.7.10.20.458
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.457
1bxoPP7Penicillopepsin-13.4.23.200.457
1klkPMDDihydrofolate reductase1.5.1.30.457
1m13HYFNuclear receptor subfamily 1 group I member 2/0.457
1vyzN5BCyclin-dependent kinase 22.7.11.220.457
1zyjBI5Mitogen-activated protein kinase 14/0.457
2c5nCK8Cyclin-dependent kinase 22.7.11.220.457
2izt23DCasein kinase I isoform gamma-32.7.11.10.457
2wgjVGHHepatocyte growth factor receptor2.7.10.10.457
2wxvWXVCyclin-dependent kinase 22.7.11.220.457
3c50ADPRhodopsin kinase/0.457
3l08ZIGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
3rni21ZCyclin-dependent kinase 22.7.11.220.457
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.457
4bi1ZO6Dual specificity protein kinase TTK2.7.12.10.457
4i0t1B6Tyrosine-protein kinase SYK2.7.10.20.457
4nky3QZSteroid 17-alpha-hydroxylase/17,20 lyase/0.457
5d12G97Proto-oncogene tyrosine-protein kinase Src2.7.10.20.457
1bl6SB6Mitogen-activated protein kinase 14/0.456
1i7iAZ2Peroxisome proliferator-activated receptor gamma/0.456
1phgMYTCamphor 5-monooxygenase1.14.15.10.456
1rfvADPPyridoxal kinase2.7.1.350.456
1t1rIMB1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.456
1ywrLI9Mitogen-activated protein kinase 14/0.456
2bl9CP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.456
2i40BLZCyclin-dependent kinase 22.7.11.220.456
2itnANPEpidermal growth factor receptor2.7.10.10.456
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.456
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.456
3dtcVINMitogen-activated protein kinase kinase kinase 92.7.11.250.456
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.456
3zxzKRWHepatocyte growth factor receptor2.7.10.10.456
4ejgNCTCytochrome P450 2A131.14.14.10.456
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.456
4hgt15GCasein kinase I isoform delta2.7.11.10.456
4idtT28Mitogen-activated protein kinase kinase kinase 142.7.11.250.456
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.456
4xlvACPInsulin receptor2.7.10.10.456
5aacVGHALK tyrosine kinase receptor2.7.10.10.456
5av3KMPDeath-associated protein kinase 12.7.11.10.456
1fmjRTLRetinol dehydratase/0.455
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.455
1y0s331Peroxisome proliferator-activated receptor delta/0.455
2hcdBIVVitamin D3 receptor A/0.455
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.455
2iw94SPCyclin-dependent kinase 22.7.11.220.455
2jkkBI9Focal adhesion kinase 12.7.10.20.455
2yxuATPPyridoxal kinase2.7.1.350.455
3cv9VDXVitamin D3 dihydroxylase/0.455
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.455
3ielU5PRibonuclease TTHA02523.10.455
3ormAGSSerine/threonine protein kinase/0.455
3r34COA4-hydroxybenzoyl-CoA thioesterase3.1.2.230.455
3zh8C58Protein kinase C iota type2.7.11.130.455
4ejh0QACytochrome P450 2A131.14.14.10.455
4fz60VGTyrosine-protein kinase SYK2.7.10.20.455
4hyu1BKMitogen-activated protein kinase 82.7.11.240.455
4ic7ANPMitogen-activated protein kinase 72.7.11.240.455
4j03FVSBifunctional epoxide hydrolase 23.1.3.760.455
4trj665Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.455
5dr6SKEAurora kinase A2.7.11.10.455
5f0a1FBcGMP-dependent protein kinase, putative/0.455
1bwsNDPGDP-L-fucose synthase/0.454
1lp4ANPCasein kinase II subunit alpha2.7.11.10.454
1uu3LY43-phosphoinositide-dependent protein kinase 12.7.11.10.454
1zhwHC2Oxysterol-binding protein homolog 4/0.454
2j0j4STFocal adhesion kinase 12.7.10.20.454
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.454
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.454
2zdu446Mitogen-activated protein kinase 102.7.11.240.454
3ddpRC8Cyclin-dependent kinase 22.7.11.220.454
3ictCOACoenzyme A disulfide reductase/0.454
3mdvCL6Cholesterol 24-hydroxylase/0.454
3nglNAPBifunctional protein FolD/0.454
3nlb5BESerine/threonine-protein kinase Chk12.7.11.10.454
3r324CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.454
3r3f4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.454
3t8oATPRhodopsin kinase/0.454
3tea4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.454
3wmxNADNAD dependent epimerase/dehydratase/0.454
4aqlTXCGuanine deaminase3.5.4.30.454
4eevL1XHepatocyte growth factor receptor2.7.10.10.454
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
4fkv61KCyclin-dependent kinase 22.7.11.220.454
4ih8B43Calmodulin-domain protein kinase 1/0.454
4l4cCAMCamphor 5-monooxygenase1.14.15.10.454
4mvfSTUCalcium-dependent protein kinase 22.7.11.10.454
4qmySTUSerine/threonine-protein kinase 242.7.11.10.454
5auvAGIDeath-associated protein kinase 12.7.11.10.454
1eupASD6-deoxyerythronolide B hydroxylase/0.453
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.453
1hfqMOTDihydrofolate reductase1.5.1.30.453
1ke7LS3Cyclin-dependent kinase 22.7.11.220.453
1rfuADPPyridoxal kinase2.7.1.350.453
1rw8580TGF-beta receptor type-12.7.11.300.453
2hwrDRDPeroxisome proliferator-activated receptor gamma/0.453
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.453
2j4z626Aurora kinase A2.7.11.10.453
2rioADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.453
2vu3LZECyclin-dependent kinase 22.7.11.220.453
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.453
2wmxZY6Serine/threonine-protein kinase Chk12.7.11.10.453
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.453
3cjgKIMVascular endothelial growth factor receptor 22.7.10.10.453
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.453
3nhwZXZRibosyldihydronicotinamide dehydrogenase [quinone]/0.453
3vid4TTVascular endothelial growth factor receptor 22.7.10.10.453
3vjhJ35Peroxisome proliferator-activated receptor gamma/0.453
4anmWULCasein kinase II subunit alpha2.7.11.10.453
4fjyFJYPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
4fod0UVALK tyrosine kinase receptor2.7.10.10.453
4gk2L66Ephrin type-A receptor 32.7.10.10.453
4l4bCAMCamphor 5-monooxygenase1.14.15.10.453
1di8DTQCyclin-dependent kinase 22.7.11.220.452
1lhvNOGSex hormone-binding globulin/0.452
1nxkSTUMAP kinase-activated protein kinase 22.7.11.10.452
1yw2PGJMitogen-activated protein kinase 14/0.452
2c0iL1GTyrosine-protein kinase HCK2.7.10.20.452
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.452
2wmvZYVSerine/threonine-protein kinase Chk12.7.11.10.452
3dgaRJ1Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.452
3inwJZBHeat shock protein HSP 90-alpha/0.452
3qaiXNNKetohexokinase/0.452
4bcoT6QCyclin-dependent kinase 22.7.11.220.452
4cd2FOLDihydrofolate reductase1.5.1.30.452
4ct2ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.452
4dquNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.452
4enhFVXCholesterol 24-hydroxylase/0.452
4ia3BIVVitamin D3 receptor A/0.452
4mq22C4Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.452
4w9wYDJBMP-2-inducible protein kinase2.7.11.10.452
5fm7ADPRuvB-like helicase/0.452
1dz6CAMCamphor 5-monooxygenase1.14.15.10.451
1ml6GBXGlutathione S-transferase A22.5.1.180.451
1pagFMPAntiviral protein I3.2.2.220.451
1xl2189Gag-Pol polyprotein3.4.23.160.451
1zarADPRIO-type serine/threonine-protein kinase Rio22.7.11.10.451
2b52D42Cyclin-dependent kinase 22.7.11.220.451
2balPQAMitogen-activated protein kinase 14/0.451
2csnCKICasein kinase I homolog 12.7.11.10.451
2iebZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.451
2wufKEM4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.451
3c1xCKKHepatocyte growth factor receptor2.7.10.10.451
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.451
3fmjFMJMitogen-activated protein kinase 14/0.451
3ggfGVDSerine/threonine-protein kinase 26/0.451
3icrCOACoenzyme A disulfide reductase/0.451
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.451
3r7iX9ICyclin-dependent kinase 22.7.11.220.451
3rk507ZCyclin-dependent kinase 22.7.11.220.451
3roc29AMitogen-activated protein kinase 14/0.451
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.451
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.451
4aa5NQBMitogen-activated protein kinase 14/0.451
4eji0QACytochrome P450 2A131.14.14.10.451
4eol1ROCyclin-dependent kinase 22.7.11.220.451
4f1sF1SPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.451
4pkl1GHUncharacterized protein/0.451
4ryvZEAProtein LlR18A/0.451
1cm8ANPMitogen-activated protein kinase 12/0.450
1cqp803Integrin alpha-L/0.450
1dawANPCasein kinase II subunit alpha2.7.11.10.450
1dxoFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.450
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.450
1k7fIAVTryptophan synthase alpha chain/0.450
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.450
1t88CAMCamphor 5-monooxygenase1.14.15.10.450
1v7aFRCAdenosine deaminase3.5.4.40.450
1zidZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.450
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.450
2fxdDR7Pol polyprotein/0.450
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.450
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.450
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.450
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.450
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.450
2yfeYFEPeroxisome proliferator-activated receptor gamma/0.450
3at3ATKCasein kinase II subunit alpha2.7.11.10.450
3bhy7CPDeath-associated protein kinase 3/0.450
3c4xATPRhodopsin kinase/0.450
3fzr3JZProtein-tyrosine kinase 2-beta2.7.10.20.450
3mqe416Prostaglandin G/H synthase 21.14.99.10.450
3qlxQLRUncharacterized protein/0.450
3qu0X40Cyclin-dependent kinase 22.7.11.220.450
3v5j0F2Tyrosine-protein kinase ITK/TSK2.7.10.20.450
3vs6VSHTyrosine-protein kinase HCK2.7.10.20.450
3zrkZRKGlycogen synthase kinase-3 beta2.7.11.260.450
4anqVGHALK tyrosine kinase receptor2.7.10.10.450
4bgiI4IEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.450
4ez50RSCyclin-dependent kinase 62.7.11.220.450
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.450
4gfo0X2Non-receptor tyrosine-protein kinase TYK22.7.10.20.450
4l521ULMitogen-activated protein kinase kinase kinase 72.7.11.250.450
4mf029ZTyrosine-protein kinase ITK/TSK2.7.10.20.450
5ai5BSUBifunctional epoxide hydrolase 23.1.3.760.450
5auuLU2Death-associated protein kinase 12.7.11.10.450
5c80URIUridine phosphorylase/0.450
1gqtACPRibokinase/0.449
1jpaANPEphrin type-B receptor 22.7.10.10.449
1kvtUPGUDP-glucose 4-epimerase5.1.3.20.449
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.449
1pxxDIFProstaglandin G/H synthase 21.14.99.10.449
1q4t4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.449
2bkzSBCCyclin-dependent kinase 22.7.11.220.449
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.449
2pvnP63Casein kinase II subunit alpha2.7.11.10.449
2pywADPMethylthioribose kinase2.7.1.1000.449
2qkrIXMCdc2-like CDK2/CDC28 like protein kinase/0.449
2w3vTOPDihydrofolate reductase/0.449
2wkmPFYHepatocyte growth factor receptor2.7.10.10.449
2wouZZFTGF-beta receptor type-12.7.11.300.449
2y6o1N1Ephrin type-A receptor 42.7.10.10.449
3i81EBIInsulin-like growth factor 1 receptor2.7.10.10.449
3i8aN22Dihydrofolate reductase1.5.1.30.449
3lctADPALK tyrosine kinase receptor2.7.10.10.449
3s4qNK0Mitogen-activated protein kinase 14/0.449
3uibSB2Putative mitogen-activated protein kinase/0.449
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.449
4b1fKRHGlutamate racemase/0.449
4bddZ0OSerine/threonine-protein kinase Chk22.7.11.10.449
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.449
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.449
4gub0Y4Casein kinase II subunit alpha2.7.11.10.449
4hy6FJ1Heat shock protein HSP 90-alpha/0.449
4l49CAMCamphor 5-monooxygenase1.14.15.10.449
4lxhC1EAlpha/beta hydrolase fold/0.449
4nj32KDCyclin-dependent kinase 22.7.11.220.449
4o4fATPKinase/0.449
4tzt468Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.449
1o5rFR9Adenosine deaminase3.5.4.40.448
1p44GEQEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.448
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.448
2fzhDH1Dihydrofolate reductase1.5.1.30.448
3nww3NWMitogen-activated protein kinase 14/0.448
3q5iANPProtein kinase, putative/0.448
3qgtCP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.448
3qlzQLZUncharacterized protein/0.448
3r3c4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.448
3ua506XCytochrome P450 2B61.14.130.448
3vewADPnebramycin 5' synthase6.1.2.20.448
4at3LTIBDNF/NT-3 growth factors receptor2.7.10.10.448
4c3yFAD3-ketosteroid dehydrogenase/0.448
4d0l093Phosphatidylinositol 4-kinase beta2.7.1.670.448
4jrvKJVEpidermal growth factor receptor2.7.10.10.448
4kb81QNCasein kinase I isoform delta2.7.11.10.448
4kwi1TJReductase homolog/0.448
1nq7ARLNuclear receptor ROR-beta/0.447
1uu7BI23-phosphoinositide-dependent protein kinase 12.7.11.10.447
1uu9BI33-phosphoinositide-dependent protein kinase 12.7.11.10.447
1vjy460TGF-beta receptor type-12.7.11.300.447
2f2cAP9Cyclin-dependent kinase 62.7.11.220.447
2g2hP16Tyrosine-protein kinase ABL12.7.10.20.447
2ow3BIMGlycogen synthase kinase-3 beta2.7.11.260.447
2qhn582Serine/threonine-protein kinase Chk12.7.11.10.447
2uzeC95Cyclin-dependent kinase 22.7.11.220.447
2vxoXMPGMP synthase [glutamine-hydrolyzing]6.3.5.20.447
2w1fL0FAurora kinase A2.7.11.10.447
2yee2ECHeat shock protein HSP 90-alpha/0.447
3a7hATPSerine/threonine-protein kinase 242.7.11.10.447
3bfb9ODPheromone-binding protein ASP1/0.447
3cquCQURAC-alpha serine/threonine-protein kinase2.7.11.10.447
3eel53TUncharacterized protein/0.447
3i60E86Mitogen-activated protein kinase 12.7.11.240.447
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.447
3w33W19Epidermal growth factor receptor2.7.10.10.447
4c35NU3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
4deg0JJHepatocyte growth factor receptor2.7.10.10.447
4e4m0NHTyrosine-protein kinase JAK2/0.447
4ftjH8KSerine/threonine-protein kinase Chk12.7.11.10.447
4fv0EK3Mitogen-activated protein kinase 12.7.11.240.447
4g160VMCasein kinase I isoform gamma-32.7.11.10.447
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.447
4l98LRGPeroxisome proliferator-activated receptor gamma/0.447
4qmnDB8Serine/threonine-protein kinase 242.7.11.10.447
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.447
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.447
1h1r6CPCyclin-dependent kinase 22.7.11.220.446
1jipKTN6-deoxyerythronolide B hydroxylase/0.446
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.446
1nhz486Glucocorticoid receptor/0.446
1q4u4CA4-hydroxybenzoyl-CoA thioesterase3.1.2.230.446
1rdt570Peroxisome proliferator-activated receptor gamma/0.446
1tezFADDeoxyribodipyrimidine photo-lyase4.1.99.30.446
1uuoBRFDihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.446
2cchATPCyclin-dependent kinase 22.7.11.220.446
2i4zDRHPeroxisome proliferator-activated receptor gamma/0.446
2r3lSCWCyclin-dependent kinase 22.7.11.220.446
2uxiG50HTH-type transcriptional regulator TtgR/0.446
2xb7GUIALK tyrosine kinase receptor2.7.10.10.446
3bheBZNGag-Pol polyprotein3.4.23.160.446
3bu5ATPInsulin receptor2.7.10.10.446
3f5p741Insulin-like growth factor 1 receptor2.7.10.10.446
3h0sB38Acetyl-CoA carboxylase/0.446
3iqzH4MF420-dependent methylenetetrahydromethanopterin dehydrogenase1.5.98.10.446
3k47D09Dihydrofolate reductase1.5.1.30.446
3oezSTIProto-oncogene tyrosine-protein kinase Src2.7.10.20.446
3owl19ECasein kinase II subunit alpha2.7.11.10.446
3rpv26ZCyclin-dependent kinase 22.7.11.220.446
3sz0FADSulfide-quinone reductase/0.446
3vetADPnebramycin 5' synthase6.1.2.20.446
3w16P9JAurora kinase A2.7.11.10.446
3we45FIRibosomal protein S6 kinase beta-12.7.11.10.446
4aa4QC0Mitogen-activated protein kinase 14/0.446
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.446
4c4jX21Dual specificity protein kinase TTK2.7.12.10.446
4c62XWWTyrosine-protein kinase JAK2/0.446
4fa60TAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
4fhj0TZPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.446
4h4xFADBiphenyl dioxygenase ferredoxin reductase subunit/0.446
4kzoNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.446
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.446
4nk92K5Fibroblast growth factor receptor 1/0.446
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.446
4xiwAZMCarbonic anhydrase, alpha type/0.446
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.446
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.446
1db1VDXVitamin D3 receptor/0.445
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.445
1qoqIGPTryptophan synthase alpha chain/0.445
1wrlTFPTroponin C, slow skeletal and cardiac muscles/0.445
2b55D31Cyclin-dependent kinase 22.7.11.220.445
2j5xGSPADP-ribosylation factor 6/0.445
2nq8ZIDEnoyl-ACP reductase/0.445
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.445
2ym3YM3Serine/threonine-protein kinase Chk12.7.11.10.445
3a7jADPSerine/threonine-protein kinase 242.7.11.10.445
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
3blrCPBCyclin-dependent kinase 92.7.11.220.445
3c13EMOCasein kinase II subunit alpha2.7.11.10.445
3iqeH4MF420-dependent methylenetetrahydromethanopterin dehydrogenase1.5.98.10.445
3nszANPCasein kinase II subunit alpha2.7.11.10.445
3ortAGSSerine/threonine protein kinase/0.445
3q9yTXQCasein kinase II subunit alpha2.7.11.10.445
3t2yFADSulfide-quinone reductase/0.445
4ap7F47Hepatocyte growth factor receptor2.7.10.10.445
4fsmHK1Serine/threonine-protein kinase Chk12.7.11.10.445
4gb90WRPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
4hvb19PPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
4ia7BIVVitamin D3 receptor A/0.445
4jlj1NMDeoxycytidine kinase2.7.1.740.445
4q5hANPProtein kinase OspG2.70.445
1bvrTHTEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
1eioGCHGastrotropin/0.444
1pkdUCNCyclin-dependent kinase 22.7.11.220.444
1tqmANPRIO-type serine/threonine-protein kinase Rio22.7.11.10.444
1zhzERGOxysterol-binding protein homolog 4/0.444
2aqhNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
2bfyH1NAurora kinase B-A2.7.11.10.444
2c6tDT5Cyclin-dependent kinase 22.7.11.220.444
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.444
2wmsZYSSerine/threonine-protein kinase Chk12.7.11.10.444
2wtiWTISerine/threonine-protein kinase Chk22.7.11.10.444
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.444
2xh9J01Uncharacterized protein/0.444
2zbzVDXVitamin D3 dihydroxylase/0.444
3efwAK8Aurora kinase A2.7.11.10.444
3flsFLSMitogen-activated protein kinase 14/0.444
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.444
3jzfJZKBiotin carboxylase6.3.4.140.444
3qqkX02Cyclin-dependent kinase 22.7.11.220.444
3qtzX42Cyclin-dependent kinase 22.7.11.220.444
3r354CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.444
3sp6IL2Peroxisome proliferator-activated receptor alpha/0.444
3ttiKBIMitogen-activated protein kinase 102.7.11.240.444
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.444
4fkt48KCyclin-dependent kinase 22.7.11.220.444
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.444
4j711JXGlycogen synthase kinase-3 beta2.7.11.260.444
4kbc1QJCasein kinase I isoform delta2.7.11.10.444
4kz01UJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.444
5c8d5ADProbable transcriptional regulator/0.444
1dkfBMSRetinoic acid receptor alpha/0.443
1py5PY1TGF-beta receptor type-12.7.11.300.443
1rc0KT5Trifunctional purine biosynthetic protein adenosine-32.1.2.20.443
1ykdCMPAdenylate cyclase/0.443
1zgaHMKIsoflavone 4'-O-methyltransferase/0.443
2gdo12CSerine/threonine-protein kinase Chk12.7.11.10.443
2hfpNSIPeroxisome proliferator-activated receptor gamma/0.443
2hk51BMTyrosine-protein kinase HCK2.7.10.20.443
2oorNADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.443
2ovmAS0Progesterone receptor/0.443
2wugHPK4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.443
2xrwANPMitogen-activated protein kinase 82.7.11.240.443
2y03Y01Beta-1 adrenergic receptor/0.443
3axwTIDCasein kinase II subunit alpha2.7.11.10.443
3ddqRRCCyclin-dependent kinase 22.7.11.220.443
3el8PD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.443
3fi3JK2Mitogen-activated protein kinase 102.7.11.240.443
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.443
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.443
3pgqGY3Acetyl-CoA carboxylase/0.443
3poz03PEpidermal growth factor receptor2.7.10.10.443
3pxkPXKFocal adhesion kinase 12.7.10.20.443
3qyw6PBMitogen-activated protein kinase 12.7.11.240.443
3sgv2BJDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.443
3tucFPWTyrosine-protein kinase SYK2.7.10.20.443
3unk0BYCyclin-dependent kinase 22.7.11.220.443
3vrwYS5Vitamin D3 receptor/0.443
4aotGW8Serine/threonine-protein kinase 102.7.11.10.443
4b4oNDPEpimerase family protein SDR39U1/0.443
4erwSTUCyclin-dependent kinase 22.7.11.220.443
4foc0UUALK tyrosine kinase receptor2.7.10.10.443
4nm0ADPGlycogen synthase kinase-3 beta2.7.11.260.443
4otiMI1Serine/threonine-protein kinase N1/0.443
4otpADPSerine/threonine-protein kinase RIO12.7.11.10.443
4wsqKSAAP2-associated protein kinase 12.7.11.10.443
4xey1N1Tyrosine-protein kinase ABL12.7.10.20.443
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.442
1h1q2A6Cyclin-dependent kinase 22.7.11.220.442
1hk5T44Serum albumin/0.442
1ie4T44Transthyretin/0.442
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.442
1jioDEB6-deoxyerythronolide B hydroxylase/0.442
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.442
1owmFADDeoxyribodipyrimidine photo-lyase4.1.99.30.442
1w6hTITPlasmepsin-23.4.23.390.442
2i0y5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.442
2idzZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.442
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.442
3bfa9ODOdorant binding protein ASP1/0.442
3d84NDPDihydrofolate reductase1.5.1.30.442
3okxSAMS-adenosyl-L-methionine-binding protein RPA0152/0.442
3pre3REPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
3tm5SFGUncharacterized protein/0.442
3tnwF18Cyclin-dependent kinase 22.7.11.220.442
3uvqFS8Mitogen-activated protein kinase 14/0.442
4ansVGHALK tyrosine kinase receptor2.7.10.10.442
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.442
4qmpDKISerine/threonine-protein kinase 242.7.11.10.442
4rqvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.442
5eaiFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.442
1f17NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.441
1ke6LS2Cyclin-dependent kinase 22.7.11.220.441
1ouy094Mitogen-activated protein kinase 14/0.441
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.441
1tdrMTXDihydrofolate reductase1.5.1.30.441
1xkkFMMEpidermal growth factor receptor2.7.10.10.441
2ay95PVAromatic-amino-acid aminotransferase2.6.1.570.441
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.441
2cmwOLPCasein kinase I isoform gamma-12.7.11.10.441
2g2fAGSTyrosine-protein kinase ABL12.7.10.20.441
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.441
2yexYEXSerine/threonine-protein kinase Chk12.7.11.10.441
3adaNADSubunit alpha of sarocosine oxidase/0.441
3b2tM33Fibroblast growth factor receptor 2/0.441
3gu6ADPDeath-associated protein kinase 12.7.11.10.441
3ictFADCoenzyme A disulfide reductase/0.441
3m42HGFMAP kinase-activated protein kinase 22.7.11.10.441
3oroAGSSerine/threonine protein kinase/0.441
3uxe465Ribosyldihydronicotinamide dehydrogenase [quinone]/0.441
3vspEK8Peroxisome proliferator-activated receptor gamma/0.441
4aoi4K0Hepatocyte growth factor receptor2.7.10.10.441
4bdfH3RSerine/threonine-protein kinase Chk22.7.11.10.441
4eomATPCyclin-dependent kinase 22.7.11.220.441
4eor4SPCyclin-dependent kinase 22.7.11.220.441
4fstHK4Serine/threonine-protein kinase Chk12.7.11.10.441
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.441
4hjoAQ4Epidermal growth factor receptor2.7.10.10.441
4i0s1B5Tyrosine-protein kinase SYK2.7.10.20.441
4ixgIXGDihydrofolate reductase1.5.1.30.441
4jqh1MFAlr2278 protein/0.441
4mcv29KProto-oncogene tyrosine-protein kinase Src2.7.10.20.441
4wq4ATPtRNA N6-adenosine threonylcarbamoyltransferase/0.441
5drdATPAurora kinase A2.7.11.10.441
1ckpPVBCyclin-dependent kinase 22.7.11.220.440
1f28UMPThymidylate synthase2.1.1.450.440
1owoFADDeoxyribodipyrimidine photo-lyase4.1.99.30.440
1p4fDRGDeath-associated protein kinase 12.7.11.10.440
1pyxANPGlycogen synthase kinase-3 beta2.7.11.260.440
1qiwDPDCalmodulin/0.440
1zz2B11Mitogen-activated protein kinase 14/0.440
2fgiPD1Fibroblast growth factor receptor 1/0.440
2ijmADPFocal adhesion kinase 12.7.10.20.440
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.440
2rhtC1E2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase3.7.1.80.440
2wecPP5Penicillopepsin-13.4.23.200.440
2yiqYIQSerine/threonine-protein kinase Chk22.7.11.10.440
2z97CAMCamphor 5-monooxygenase1.14.15.10.440
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.440
3b9lAZZSerum albumin/0.440
3clbNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.440
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.440
3kytHC2Nuclear receptor ROR-gamma/0.440
3nj0PYVAbscisic acid receptor PYL2/0.440
3pe6ZYHMonoglyceride lipase/0.440
3r71X86Cyclin-dependent kinase 22.7.11.220.440
3r9hZ67Cyclin-dependent kinase 22.7.11.220.440
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.440
3tvuB37Acetyl-CoA carboxylase/0.440
3uli1N3Cyclin-dependent kinase 22.7.11.220.440
3vo30KFVascular endothelial growth factor receptor 22.7.10.10.440
3w1wCHDFerrochelatase, mitochondrial4.99.1.10.440
4bcqTJFCyclin-dependent kinase 22.7.11.220.440
4bdgP3JSerine/threonine-protein kinase Chk22.7.11.10.440
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.440
4cfnJYMCyclin-dependent kinase 22.7.11.220.440
4dc0NDPPutative ketoacyl reductase1.3.10.440
4g2gTDHMycocyclosin synthase1.14.21.90.440
4gk3L87Ephrin type-A receptor 32.7.10.10.440
4h9814QUncharacterized protein/0.440
4haiI23Bifunctional epoxide hydrolase 23.1.3.760.440
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.440
4hgl0YOCasein kinase I isoform gamma-32.7.11.10.440
4jx1CAMCamphor 5-monooxygenase1.14.15.10.440
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.440
4mfqCOAUncharacterized protein/0.440
4qysPLRTryptophan synthase beta chain 24.2.1.200.440
4wuoNAD3-isopropylmalate dehydrogenase1.1.1.850.440
4xwtU5PRibonuclease J/0.440
5aabVGHALK tyrosine kinase receptor2.7.10.10.440
5akk1P8Bifunctional epoxide hydrolase 23.1.3.760.440
5e8ySTUTGF-beta receptor type-22.7.11.300.440