Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
PDB ID | HET | Uniprot Name | EC Number |
---|---|---|---|
4cf2 | 3GM | Integrase |
PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
---|---|---|---|---|---|
4cf2 | 3GM | Integrase | / | 1.000 | |
4cju | JNS | Integrase | / | 0.674 | |
4cjp | 4D2 | Integrase | / | 0.669 | |
4cef | D0T | Integrase | / | 0.668 | |
4ce9 | O3N | Integrase | / | 0.667 | |
4ces | NFW | Integrase | / | 0.657 | |
4cgj | NZL | Integrase | / | 0.655 | |
4ck2 | NVU | Integrase | / | 0.653 | |
4cif | JDX | Integrase | / | 0.648 | |
4cig | X0P | Integrase | / | 0.648 | |
4cfc | 7NV | Integrase | / | 0.647 | |
3zsw | ZSW | Integrase | / | 0.645 | |
4cjk | H39 | Integrase | / | 0.636 | |
4cer | VL4 | Integrase | / | 0.634 | |
4cf0 | O5U | Integrase | / | 0.630 | |
3zsr | O3N | Integrase | / | 0.629 | |
4cez | O3N | Integrase | / | 0.629 | |
4ced | 9NS | Integrase | / | 0.627 | |
3zt3 | ZT4 | Integrase | / | 0.626 | |
4cgh | LOZ | Integrase | / | 0.624 | |
4chy | C5Q | Integrase | / | 0.624 | |
4cjf | RVN | Integrase | / | 0.624 | |
4cie | Y7N | Integrase | / | 0.622 | |
4cea | ZSW | Integrase | / | 0.621 | |
4cfb | OM3 | Integrase | / | 0.620 | |
3zt0 | ZT0 | Integrase | / | 0.618 | |
4cfa | WOP | Integrase | / | 0.618 | |
4cgi | NZL | Integrase | / | 0.613 | |
4cf8 | V7H | Integrase | / | 0.611 | |
4cj5 | 4VW | Integrase | / | 0.609 | |
4ceq | QCH | Integrase | / | 0.608 | |
4cjr | FYM | Integrase | / | 0.608 | |
4cgd | 8P3 | Integrase | / | 0.607 | |
4cjq | VXO | Integrase | / | 0.607 | |
4cfd | S8Y | Integrase | / | 0.605 | |
4ceo | G0T | Integrase | / | 0.598 | |
4cf1 | IY7 | Integrase | / | 0.598 | |
4cec | 2SS | Integrase | / | 0.587 | |
3zsv | ZSV | Integrase | / | 0.585 | |
4ceb | ZSV | Integrase | / | 0.585 | |
4cjs | L0Y | Integrase | / | 0.582 | |
4cj3 | E4F | Integrase | / | 0.581 | |
3zsz | OM2 | Integrase | / | 0.579 | |
3zsq | O4N | Integrase | / | 0.578 | |
3zsy | OM3 | Integrase | / | 0.577 | |
4cee | B0T | Integrase | / | 0.575 | |
4cgg | K5Q | Integrase | / | 0.575 | |
4cje | Q31 | Integrase | / | 0.575 | |
3zsx | N44 | Integrase | / | 0.567 | |
4ck3 | K1T | Integrase | / | 0.564 | |
4chq | CWU | Integrase | / | 0.558 | |
3zt2 | ZT2 | Integrase | / | 0.552 | |
4cj4 | S3G | Integrase | / | 0.551 | |
3zcm | PX3 | Integrase | / | 0.545 | |
4ck1 | OM1 | Integrase | / | 0.545 | |
3zt1 | OM1 | Integrase | / | 0.527 | |
4c02 | TAK | Activin receptor type-1 | 2.7.11.30 | 0.500 | |
2bxm | IMN | Serum albumin | / | 0.499 | |
4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.493 | |
4cgf | UJ6 | Integrase | / | 0.492 | |
3cxw | 7CP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.490 | |
4fv7 | E94 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.487 | |
2xj2 | 985 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.486 | |
3bht | MFR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.486 | |
4fhf | 0TT | Spore photoproduct lyase | / | 0.486 | |
4b8w | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.484 | |
4bzo | 676 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.482 | |
5iu4 | ZMA | Adenosine receptor A2a | / | 0.482 | |
2xvv | 9DN | Serum albumin | / | 0.481 | |
4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.481 | |
4bzn | UGX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.481 | |
1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.480 | |
1ef9 | 2CP | Methylmalonyl-CoA decarboxylase | 4.1.1.41 | 0.480 | |
4eji | 0QA | Cytochrome P450 2A13 | 1.14.14.1 | 0.480 | |
2vke | TAC | Tetracycline repressor protein class D | / | 0.478 | |
2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.478 | |
5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.478 | |
3pe2 | E1B | Casein kinase II subunit alpha | 2.7.11.1 | 0.477 | |
4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.477 | |
4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.477 | |
1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
2bfm | TOP | Pteridine reductase 1 | 1.5.1.33 | 0.476 | |
2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.476 | |
2c47 | 5ID | Casein kinase I isoform gamma-2 | / | 0.476 | |
4acg | 6LQ | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.476 | |
4fgc | PQ0 | NADPH-dependent 7-cyano-7-deazaguanine reductase | 1.7.1.13 | 0.476 | |
4hyh | 1AM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.475 | |
4kvg | GTP | Ras-related protein Rap-1A | / | 0.475 | |
2bxq | IMN | Serum albumin | / | 0.474 | |
3own | 3OW | Renin | 3.4.23.15 | 0.474 | |
2xvu | 9DN | Serum albumin | / | 0.473 | |
3cy2 | MB9 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.473 | |
5ecc | NAP | Dehydrofolate reductase type I | / | 0.473 | |
4aw0 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.472 | |
1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
1t2d | NAD | L-lactate dehydrogenase | 1.1.1.27 | 0.471 | |
1v9a | SAH | Uncharacterized protein | / | 0.471 | |
3g5q | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.471 | |
4b8z | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.471 | |
1fmj | RTL | Retinol dehydratase | / | 0.470 | |
1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.470 | |
1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.470 | |
3iae | D7K | Benzaldehyde lyase | / | 0.470 | |
3pqb | VGP | Putative oxidoreductase | / | 0.470 | |
1cjt | FOK | Adenylate cyclase type 2 | / | 0.469 | |
1cjt | FOK | Adenylate cyclase type 5 | / | 0.469 | |
1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.469 | |
2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.468 | |
2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.468 | |
2xvw | 9NR | Serum albumin | / | 0.468 | |
2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.468 | |
4u9a | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.468 | |
4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.468 | |
1x8l | OXR | Retinol dehydratase | / | 0.467 | |
2z4y | 252 | Geranylgeranyl pyrophosphate synthase | / | 0.467 | |
4dym | IYZ | Activin receptor type-1 | 2.7.11.30 | 0.467 | |
1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
2ji9 | TPW | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.466 | |
3elm | 24F | Collagenase 3 | 3.4.24 | 0.466 | |
3mg3 | ECH | Orange carotenoid-binding protein | / | 0.466 | |
3mtf | A3F | Activin receptor type-1 | 2.7.11.30 | 0.466 | |
4cf7 | ADP | Adenylate kinase | / | 0.466 | |
4zla | BES | Cytosol aminopeptidase | 3.4.11.1 | 0.466 | |
5iub | CLR | Adenosine receptor A2a | / | 0.466 | |
1byg | STU | Tyrosine-protein kinase CSK | / | 0.465 | |
3be9 | P04 | Casein kinase II subunit alpha | 2.7.11.1 | 0.465 | |
4eoi | 1RO | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.465 | |
4hyi | 1AO | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.465 | |
1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.464 | |
2p8u | COA | Hydroxymethylglutaryl-CoA synthase, cytoplasmic | 2.3.3.10 | 0.464 | |
3vrw | YS5 | Vitamin D3 receptor | / | 0.464 | |
3vt3 | VDX | Vitamin D3 receptor | / | 0.464 | |
4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.464 | |
4gj3 | 0XP | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.464 | |
4obu | PLP | Pyridoxal-dependent decarboxylase domain protein | / | 0.464 | |
1cs4 | FOK | Adenylate cyclase type 2 | / | 0.463 | |
1cs4 | FOK | Adenylate cyclase type 5 | / | 0.463 | |
3oom | 507 | Activin receptor type-1 | 2.7.11.30 | 0.463 | |
3v2u | ATP | Protein GAL3 | / | 0.463 | |
4yt5 | H4M | H(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ1338 | / | 0.463 | |
1di8 | DTQ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.462 | |
1fml | RTL | Retinol dehydratase | / | 0.462 | |
2cgu | 3A3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.462 | |
2rgx | AP5 | Adenylate kinase | / | 0.462 | |
2ydo | ADN | Adenosine receptor A2a | / | 0.462 | |
4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.462 | |
4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.462 | |
4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.462 | |
4zj8 | SUV | Orexin receptor type 1 | / | 0.462 | |
1bws | NDP | GDP-L-fucose synthase | / | 0.461 | |
1eh4 | IC1 | Casein kinase I homolog 1 | 2.7.11.1 | 0.461 | |
1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
2c31 | TZD | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.461 | |
2hxq | 373 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.461 | |
2z4s | ADP | Chromosomal replication initiator protein DnaA | / | 0.461 | |
3gob | HXX | DdmC | / | 0.461 | |
3mvm | 39P | Mitogen-activated protein kinase 14 | / | 0.461 | |
4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.461 | |
4m49 | 22Y | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.461 | |
4ng2 | OHN | Transcriptional activator protein LasR | / | 0.461 | |
4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.461 | |
4y8w | STR | Steroid 21-hydroxylase | / | 0.461 | |
4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.461 | |
1cju | FOK | Adenylate cyclase type 2 | / | 0.460 | |
1cju | FOK | Adenylate cyclase type 5 | / | 0.460 | |
1l8q | ADP | Chromosomal replication initiator protein DnaA | / | 0.460 | |
1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.460 | |
1pzh | NAD | Lactate dehydrogenase | / | 0.460 | |
2ops | HBQ | Gag-Pol polyprotein | 2.7.7.49 | 0.460 | |
2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.460 | |
3hdm | MMG | Serine/threonine-protein kinase Sgk1 | 2.7.11.1 | 0.460 | |
3vs4 | VSF | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.460 | |
4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.460 | |
4fv3 | EK6 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.460 | |
4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.460 | |
1eio | GCH | Gastrotropin | / | 0.459 | |
1vik | BAY | Gag-Pol polyprotein | / | 0.459 | |
2bjh | FER | Feruloyl esterase A | 3.1.1.73 | 0.459 | |
2bri | ANP | Uridylate kinase | 2.7.4.22 | 0.459 | |
2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.459 | |
2npx | NAD | NADH peroxidase | 1.11.1.1 | 0.459 | |
2zev | B71 | Geranylgeranyl pyrophosphate synthase | / | 0.459 | |
2zm4 | KSM | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.459 | |
3ac5 | KZM | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.459 | |
3lqf | NAD | Galactitol dehydrogenase | / | 0.459 | |
3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.459 | |
3qiz | QI2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.459 | |
4hia | FMN | LOV protein | / | 0.459 | |
4jaj | XU1 | Aurora kinase A | 2.7.11.1 | 0.459 | |
4ks8 | B49 | Serine/threonine-protein kinase PAK 6 | 2.7.11.1 | 0.459 | |
4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.459 | |
5hes | 032 | Mitogen-activated protein kinase kinase kinase 20 | 2.7.11.25 | 0.459 | |
1sow | NAD | L-lactate dehydrogenase | 1.1.1.27 | 0.458 | |
2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.458 | |
2ohv | NHL | Glutamate racemase | / | 0.458 | |
3ac3 | KSH | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.458 | |
3b9l | AZZ | Serum albumin | / | 0.458 | |
3dog | NNN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
3pl8 | FAD | Pyranose 2-oxidase | / | 0.458 | |
3zdu | 38R | Cyclin-dependent kinase-like 3 | 2.7.11.22 | 0.458 | |
4ajn | 88V | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.458 | |
4nd4 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.458 | |
5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.458 | |
1pxx | DIF | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.457 | |
2brb | PFQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.457 | |
2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.457 | |
2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.457 | |
2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.457 | |
2vwq | NAP | Glucose 1-dehydrogenase | / | 0.457 | |
2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
3cbl | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.457 | |
3ddw | 055 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.457 | |
3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.457 | |
3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.457 | |
3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.457 | |
3ids | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.457 | |
3koo | 24D | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.457 | |
3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.457 | |
3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.457 | |
4a31 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.457 | |
4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.457 | |
4em9 | TCE | Peroxisome proliferator-activated receptor gamma | / | 0.457 | |
4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.457 | |
4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.457 | |
1c1d | NAI | Phenylalanine dehydrogenase | / | 0.456 | |
1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
1k74 | 544 | Peroxisome proliferator-activated receptor gamma | / | 0.456 | |
1osv | CHC | Bile acid receptor | / | 0.456 | |
1pox | FAD | Pyruvate oxidase | 1.2.3.3 | 0.456 | |
1qoq | IGP | Tryptophan synthase alpha chain | / | 0.456 | |
1zem | NAD | Xylitol dehydrogenase | / | 0.456 | |
1zys | 199 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.456 | |
2cch | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
2ijg | FAD | Cryptochrome DASH, chloroplastic/mitochondrial | / | 0.456 | |
2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.456 | |
2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
2z9d | FMN | FMN-dependent NADH-azoreductase | / | 0.456 | |
3edj | BCD | Cyclomaltodextrinase | / | 0.456 | |
3ig6 | 438 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.456 | |
3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
4c3x | FAD | 3-ketosteroid dehydrogenase | / | 0.456 | |
4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
4ie6 | UN9 | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.456 | |
4tzt | 468 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.456 | |
5ajq | DB8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.456 | |
1fdo | MGD | Formate dehydrogenase H | 1.1.99.33 | 0.455 | |
1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.455 | |
1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.455 | |
1ht5 | FL2 | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.455 | |
1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.455 | |
1kzu | RG1 | Light-harvesting protein B-800/850 alpha chain | / | 0.455 | |
1kzu | RG1 | Light-harvesting protein B-800/850 beta chain | / | 0.455 | |
1zc3 | GNP | Ras-related protein Ral-A | / | 0.455 | |
2e9n | 76A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.455 | |
2ij7 | TPF | Mycocyclosin synthase | 1.14.21.9 | 0.455 | |
2pvn | P63 | Casein kinase II subunit alpha | 2.7.11.1 | 0.455 | |
2q5q | TPW | Indole-3-pyruvate decarboxylase | 4.1.1.74 | 0.455 | |
2rkv | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.455 | |
2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.455 | |
2wih | P48 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
2xa4 | AZ5 | Tyrosine-protein kinase JAK2 | / | 0.455 | |
2xb5 | I7T | Tetracycline repressor protein class D | / | 0.455 | |
3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.455 | |
3pd3 | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.455 | |
4bfm | ANP | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.455 | |
4bgg | 844 | Activin receptor type-1 | 2.7.11.30 | 0.455 | |
4fod | 0UV | ALK tyrosine kinase receptor | 2.7.10.1 | 0.455 | |
4gll | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.455 | |
1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.454 | |
1h1r | 6CP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
1nqo | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.454 | |
1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.454 | |
1y5r | C0R | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.454 | |
1ykd | CMP | Adenylate cyclase | / | 0.454 | |
2e8t | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.454 | |
2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.454 | |
2nq8 | ZID | Enoyl-ACP reductase | / | 0.454 | |
2wxv | WXV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
3a3y | OBN | Sodium/potassium-transporting ATPase subunit alpha | / | 0.454 | |
3c16 | FOK | Adenylate cyclase type 2 | / | 0.454 | |
3c16 | FOK | Adenylate cyclase type 5 | / | 0.454 | |
3d7k | D7K | Benzaldehyde lyase | / | 0.454 | |
3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.454 | |
4db1 | ANP | Myosin-7 | / | 0.454 | |
4i6g | FAD | Cryptochrome-2 | / | 0.454 | |
4iql | FMN | Enoyl-(Acyl-carrier-protein) reductase II | / | 0.454 | |
4kip | 1R9 | Mitogen-activated protein kinase 14 | / | 0.454 | |
4mq2 | 2C4 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | 2.7.12.1 | 0.454 | |
4mv8 | ACP | Biotin carboxylase | 6.3.4.14 | 0.454 | |
4mxo | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.454 | |
4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.454 | |
5iu8 | 6DZ | Adenosine receptor A2a | / | 0.454 | |
5dhg | DGV | Nociceptin receptor | / | 0.454 | |
1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.453 | |
1tl7 | FOK | Adenylate cyclase type 2 | / | 0.453 | |
1tl7 | FOK | Adenylate cyclase type 5 | / | 0.453 | |
2nvb | NAP | NADP-dependent isopropanol dehydrogenase | 1.1.1.80 | 0.453 | |
2ojg | 19A | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.453 | |
2wip | P49 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
2xs0 | ANP | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.453 | |
2xtn | GTP | GTPase IMAP family member 2 | / | 0.453 | |
3dd1 | 25D | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.453 | |
3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.453 | |
3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.453 | |
3fr8 | NDP | Ketol-acid reductoisomerase, chloroplastic | 1.1.1.86 | 0.453 | |
3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.453 | |
3otf | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | / | 0.453 | |
3vf8 | 0JE | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.453 | |
4bdf | H3R | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.453 | |
4bdh | WVI | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.453 | |
4hjo | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.453 | |
4wfr | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.453 | |
5ack | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.453 | |
5k2d | ZMA | Adenosine receptor A2a | / | 0.453 | |
1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
1cjk | FOK | Adenylate cyclase type 2 | / | 0.452 | |
1cjk | FOK | Adenylate cyclase type 5 | / | 0.452 | |
1e1l | NAP | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.452 | |
1e3r | AND | Steroid Delta-isomerase | 5.3.3.1 | 0.452 | |
1kfb | IGP | Tryptophan synthase alpha chain | / | 0.452 | |
1uh5 | TCL | Enoyl-ACP reductase | / | 0.452 | |
1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.452 | |
2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.452 | |
2vqz | MGT | Polymerase basic protein 2 | / | 0.452 | |
3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.452 | |
3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.452 | |
3lfm | 3DT | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.452 | |
3lsi | FAD | Pyranose 2-oxidase | / | 0.452 | |
3lzw | NAP | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.452 | |
3p7n | FMN | Light-activated DNA-binding protein EL222 | / | 0.452 | |
3qf9 | NM8 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.452 | |
3r9n | Z68 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.452 | |
4j7u | NAP | Sepiapterin reductase | 1.1.1.153 | 0.452 | |
4jb1 | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.452 | |
4nfn | 2KC | Tau-tubulin kinase 1 | 2.7.11.1 | 0.452 | |
4ozt | P1A | Ecdysone receptor, putative | / | 0.452 | |
4pd6 | URI | Nucleoside permease | / | 0.452 | |
1a59 | COA | 2-methylcitrate synthase | / | 0.451 | |
1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.451 | |
1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.451 | |
1h1s | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
1jtu | LYB | Thymidylate synthase | / | 0.451 | |
1kt8 | ILP | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.451 | |
1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.451 | |
1nzd | UPG | DNA beta-glucosyltransferase | / | 0.451 | |
1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.451 | |
1r6g | 442 | Thyroid hormone receptor beta | / | 0.451 | |
2a4x | BLM | Mitomycin-binding protein | / | 0.451 | |
2e93 | B29 | Geranylgeranyl pyrophosphate synthase | / | 0.451 | |
2hxl | 422 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.451 | |
2r7b | 253 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.451 | |
2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.451 | |
3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.451 | |
3gu8 | 3GU | Death-associated protein kinase 1 | 2.7.11.1 | 0.451 | |
3kdu | NKS | Peroxisome proliferator-activated receptor alpha | / | 0.451 | |
3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.451 | |
3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.451 | |
3up5 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.451 | |
4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.451 | |
4xcv | NDP | Probable hydroxyacid dehydrogenase protein | / | 0.451 | |
4xg1 | LLP | Diaminopimelate decarboxylase | / | 0.451 | |
5f0a | 1FB | cGMP-dependent protein kinase, putative | / | 0.451 | |
1e92 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.450 | |
1hk5 | T44 | Serum albumin | / | 0.450 | |
1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.450 | |
1s60 | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.450 | |
1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.450 | |
1wwk | NAD | 307aa long hypothetical phosphoglycerate dehydrogenase | / | 0.450 | |
2c0o | L2G | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.450 | |
2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.450 | |
2e4n | SAH | Diphthine synthase | / | 0.450 | |
2ele | SAH | Diphthine synthase | / | 0.450 | |
2fhn | BNI | Avidin-related protein 4/5 | / | 0.450 | |
2ydi | YDI | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.450 | |
3czr | 3CZ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.450 | |
3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.450 | |
3uku | C69 | Actin-related protein 3 | / | 0.450 | |
3wrl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
3x04 | GNP | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | 2.7.1.149 | 0.450 | |
4kiq | 1RA | Mitogen-activated protein kinase 14 | / | 0.450 | |
4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.450 | |
5a3b | APR | SIR2 family protein | / | 0.450 | |
5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.450 | |
1d2s | DHT | Sex hormone-binding globulin | / | 0.449 | |
1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.449 | |
1u4o | NDD | L-lactate dehydrogenase | 1.1.1.27 | 0.449 | |
2j14 | GNI | Peroxisome proliferator-activated receptor delta | / | 0.449 | |
2pin | 4HY | Thyroid hormone receptor beta | / | 0.449 | |
2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.449 | |
3owa | FAD | Acyl-CoA dehydrogenase | / | 0.449 | |
3r28 | XA0 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
3r7e | X88 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.449 | |
3vjo | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.449 | |
4bdd | Z0O | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.449 | |
4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.449 | |
5c1g | GDU | Histo-blood group ABO system transferase | / | 0.449 | |
5k2b | ZMA | Adenosine receptor A2a | / | 0.449 | |
1dkf | BMS | Retinoic acid receptor alpha | / | 0.448 | |
1h65 | GDP | Translocase of chloroplast 34 | 3.6.5 | 0.448 | |
1hbv | GAN | Gag-Pol polyprotein | / | 0.448 | |
1hqu | HBY | Gag-Pol polyprotein | 2.7.7.49 | 0.448 | |
1kc1 | NDP | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.448 | |
1pzg | A3D | Lactate dehydrogenase | / | 0.448 | |
1q43 | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 | / | 0.448 | |
2brn | DF1 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
2d81 | RB3 | Poly(3-hydroxybutyrate) depolymerase | / | 0.448 | |
2fr1 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.448 | |
2hk5 | 1BM | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.448 | |
2ix5 | FAD | Acyl-coenzyme A oxidase 4, peroxisomal | 1.3.3.6 | 0.448 | |
2pvl | P55 | Casein kinase II subunit alpha | 2.7.11.1 | 0.448 | |
2xke | WI2 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.448 | |
2xng | A0H | Aurora kinase A | 2.7.11.1 | 0.448 | |
3c4e | C4E | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.448 | |
3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.448 | |
4ajj | 88R | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.448 | |
4aqc | 88A | Tyrosine-protein kinase JAK2 | / | 0.448 | |
4cvl | ACP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.448 | |
4e9a | QAP | Peptide deformylase | / | 0.448 | |
4mxx | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.448 | |
4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.448 | |
4nfs | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.448 | |
4rrr | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.448 | |
1lwl | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.447 | |
1uxk | NAD | Malate dehydrogenase | / | 0.447 | |
1xtr | GNP | GTP-binding protein Rheb | / | 0.447 | |
1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.447 | |
2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.447 | |
2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
2vpr | TDC | Tetracycline repressor protein class H | / | 0.447 | |
2y05 | NAP | Prostaglandin reductase 1 | / | 0.447 | |
2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.447 | |
3acj | KSS | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.447 | |
3c14 | FOK | Adenylate cyclase type 2 | / | 0.447 | |
3c14 | FOK | Adenylate cyclase type 5 | / | 0.447 | |
3ddq | RRC | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.447 | |
3ijd | C2F | Methylenetetrahydrofolate reductase | / | 0.447 | |
3mkn | DNB | Pyrimidine-specific ribonucleoside hydrolase RihB | / | 0.447 | |
3o15 | 3NM | Thiamine-phosphate synthase | / | 0.447 | |
3pe6 | ZYH | Monoglyceride lipase | / | 0.447 | |
3qw4 | U5P | Orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative | / | 0.447 | |
3rq6 | APR | ADP-dependent (S)-NAD(P)H-hydrate dehydratase | / | 0.447 | |
3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.447 | |
3sf6 | FDA | Glutaryl-CoA dehydrogenase | / | 0.447 | |
3u9n | 09H | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
3vso | EK1 | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
3vsp | EK8 | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.447 | |
4dgn | LU2 | Casein kinase II subunit alpha | 2.7.11.1 | 0.447 | |
4eet | FMN | Phototropin-2 | 2.7.11.1 | 0.447 | |
4kl9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
4zwp | M44 | Xaa-Pro dipeptidase | 3.4.13.9 | 0.447 | |
5dp2 | NAP | CurF | / | 0.447 | |
5iqi | GNP | Bifunctional AAC/APH | 2.3.1 | 0.447 | |
1cqp | 803 | Integrin alpha-L | / | 0.446 | |
1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.446 | |
1h62 | ANB | Pentaerythritol tetranitrate reductase | / | 0.446 | |
1p0h | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.446 | |
1tdr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.446 | |
2e8r | SAH | Diphthine synthase | / | 0.446 | |
2e9p | 77A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
2i4z | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
2z52 | H23 | Geranylgeranyl pyrophosphate synthase | / | 0.446 | |
3jpv | 1DR | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.446 | |
3kvx | FMY | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.446 | |
3ows | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.446 | |
3t4n | ADP | 5'-AMP-activated protein kinase subunit gamma | / | 0.446 | |
3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.446 | |
3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.446 | |
4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.446 | |
4bhw | 01K | Histone acetyltransferase p300 | / | 0.446 | |
4dfn | 0K1 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.446 | |
4fmx | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.446 | |
4hnh | NAP | NAD-dependent epimerase/dehydratase | / | 0.446 | |
5iw4 | NAD | NADH pyrophosphatase | / | 0.446 | |
5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.446 | |
3eml | ZMA | Adenosine receptor A2a | / | 0.446 | |
1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
1crb | RTL | Retinol-binding protein 1 | / | 0.445 | |
1equ | EQI | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.445 | |
1fxs | NAP | GDP-L-fucose synthase | / | 0.445 | |
1jwt | BLI | Prothrombin | 3.4.21.5 | 0.445 | |
1lp4 | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.445 | |
1nq5 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.445 | |
1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
1u59 | STU | Tyrosine-protein kinase ZAP-70 | 2.7.10.2 | 0.445 | |
1upw | 444 | Oxysterols receptor LXR-beta | / | 0.445 | |
1zc4 | GNP | Ras-related protein Ral-A | / | 0.445 | |
2dv3 | SAH | Diphthine synthase | / | 0.445 | |
2gtm | LID | Mitogen-activated protein kinase 14 | / | 0.445 | |
2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.445 | |
2npi | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.445 | |
2o7p | NAP | Riboflavin biosynthesis protein RibD | / | 0.445 | |
2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.445 | |
2v4l | ABJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
2vz6 | FEF | Calcium/calmodulin-dependent protein kinase type II subunit alpha | 2.7.11.17 | 0.445 | |
2z50 | 028 | Geranylgeranyl pyrophosphate synthase | / | 0.445 | |
3bv2 | P38 | Mitogen-activated protein kinase 14 | / | 0.445 | |
3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
3o3j | BB4 | Peptide deformylase 1B, chloroplastic/mitochondrial | 3.5.1.88 | 0.445 | |
3u8k | 09P | Acetylcholine-binding protein | / | 0.445 | |
3vf9 | 477 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.445 | |
3vs6 | VSH | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.445 | |
3vt7 | VDX | Vitamin D3 receptor | / | 0.445 | |
4bdb | ODO | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.445 | |
4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.445 | |
4bw1 | S5B | Bromodomain-containing protein 4 | / | 0.445 | |
4eh9 | IRG | Mitogen-activated protein kinase 14 | / | 0.445 | |
4ux9 | ANP | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.445 | |
4wa9 | AXI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.445 | |
5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.445 | |
5hyn | SAH | Histone-lysine N-methyltransferase EZH2 | 2.1.1.43 | 0.445 | |
1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
1efp | FAD | Electron transfer flavoprotein subunit alpha | / | 0.444 | |
1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.444 | |
1i24 | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.444 | |
1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.444 | |
1q41 | IXM | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.444 | |
1r2j | FAD | FkbI | / | 0.444 | |
1svl | ADP | Large T antigen | 3.6.4 | 0.444 | |
1uxj | NAD | Malate dehydrogenase | / | 0.444 | |
1xdd | AAY | Integrin alpha-L | / | 0.444 | |
2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.444 | |
2el3 | SAH | Diphthine synthase | / | 0.444 | |
2g1n | 1IG | Renin | 3.4.23.15 | 0.444 | |
2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.444 | |
2j9l | ATP | H(+)/Cl(-) exchange transporter 5 | / | 0.444 | |
2owk | SAH | Diphthine synthase | / | 0.444 | |
2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.444 | |
2xf3 | J01 | Uncharacterized protein | / | 0.444 | |
2xnb | Y8L | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
2ym4 | 4YM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
2zva | 1N1 | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.444 | |
3bpz | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 | / | 0.444 | |
3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.444 | |
3maa | FKP | Adenylate cyclase type 2 | / | 0.444 | |
3maa | FKP | Adenylate cyclase type 5 | / | 0.444 | |
3rm6 | 18Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
3she | I85 | MAP kinase-activated protein kinase 3 | 2.7.11.1 | 0.444 | |
3tox | NAP | Putative oxidoreductase | / | 0.444 | |
3vtd | TKD | Vitamin D3 receptor | / | 0.444 | |
4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.444 | |
4anv | 751 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
4at3 | LTI | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.444 | |
4awo | 99B | Heat shock protein HSP 90-alpha | / | 0.444 | |
4b4d | FAD | Ferredoxin-NADP reductase | / | 0.444 | |
4btj | ADP | Tau-tubulin kinase 1 | 2.7.11.1 | 0.444 | |
4c9p | CAM | Cytochrome P450 | / | 0.444 | |
4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.444 | |
4eso | NAP | Putative oxidoreductase | / | 0.444 | |
4k0z | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.444 | |
4l8u | 9AZ | Serum albumin | / | 0.444 | |
4q71 | FAD | Bifunctional protein PutA | / | 0.444 | |
4r1l | ADP | Phenylacetate-coenzyme A ligase | / | 0.444 | |
4xrq | 1B0 | Gag polyprotein | / | 0.444 | |
4xym | COA | Acyl-CoA synthetase (NDP forming) | / | 0.444 | |
5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.444 | |
5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.444 | |
3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.444 | |
1f0q | EMO | Casein kinase II subunit alpha | 2.7.11.1 | 0.443 | |
1hdr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.443 | |
1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.443 | |
1n6l | GTP | Ras-related protein Rab-5A | / | 0.443 | |
1oiy | N41 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
2acl | L05 | Oxysterols receptor LXR-alpha | / | 0.443 | |
2r3f | SC8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
2xrw | ANP | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.443 | |
2yaa | ATP | Death-associated protein kinase 2 | / | 0.443 | |
3cge | NDP | Coenzyme A disulfide reductase | / | 0.443 | |
3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
3flz | FLZ | Mitogen-activated protein kinase 14 | / | 0.443 | |
3gvh | NAD | Malate dehydrogenase | / | 0.443 | |
3mt8 | 17T | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.443 | |
3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.443 | |
3vyf | VYF | Renin | 3.4.23.15 | 0.443 | |
3w0g | W07 | Vitamin D3 receptor | / | 0.443 | |
3w1w | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.443 | |
4awq | 592 | Heat shock protein HSP 90-alpha | / | 0.443 | |
4b7x | NAP | Probable oxidoreductase | / | 0.443 | |
4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.443 | |
4ez3 | 0S0 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.443 | |
4ki8 | ADP | 60 kDa chaperonin | / | 0.443 | |
4rje | FNR | Lactate oxidase | / | 0.443 | |
4trj | 665 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
4y93 | 746 | Tyrosine-protein kinase | / | 0.443 | |
5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
1b3r | NAD | Adenosylhomocysteinase | 3.3.1.1 | 0.442 | |
1bmd | NAD | Malate dehydrogenase | / | 0.442 | |
1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.442 | |
1cjv | FOK | Adenylate cyclase type 2 | / | 0.442 | |
1cjv | FOK | Adenylate cyclase type 5 | / | 0.442 | |
1mdt | APU | Diphtheria toxin | / | 0.442 | |
1s0x | C3S | Nuclear receptor ROR-alpha | / | 0.442 | |
1sm2 | STU | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.442 | |
1x14 | NAD | NAD(P) transhydrogenase subunit alpha | 1.6.1.2 | 0.442 | |
2aba | STR | Pentaerythritol tetranitrate reductase | / | 0.442 | |
2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
2e9u | A25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.442 | |
2gnh | H52 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.442 | |
2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.442 | |
2wpa | 889 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
2ylr | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.442 | |
2zjw | REF | Casein kinase II subunit alpha | 2.7.11.1 | 0.442 | |
3dey | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.442 | |
3el8 | PD5 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.442 | |
3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.442 | |
3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
3gb4 | D3M | DdmC | / | 0.442 | |
3k14 | 535 | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | / | 0.442 | |
3klm | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.442 | |
3qiy | QI1 | Botulinum neurotoxin type A | 3.4.24.69 | 0.442 | |
3rni | 21Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
3uzp | 0CK | Casein kinase I isoform delta | 2.7.11.1 | 0.442 | |
4c34 | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.442 | |
4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.442 | |
4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.442 | |
4ha6 | PXM | Pyridoxine 4-oxidase | / | 0.442 | |
4l4f | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
4l4x | NDP | AmphI | / | 0.442 | |
4l5b | 1UX | Deoxycytidine kinase | 2.7.1.74 | 0.442 | |
4qmx | H8H | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.442 | |
4tmc | FMN | Old yellow enzyme | / | 0.442 | |
4wqm | FAD | Toluene-4-monooxygenase electron transfer component | 1.18.1.3 | 0.442 | |
4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.442 | |
4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.442 | |
1bdl | IM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.441 | |
1k8y | 13P | Tryptophan synthase alpha chain | / | 0.441 | |
1nhh | ANP | DNA mismatch repair protein MutL | / | 0.441 | |
1pzf | A3D | Lactate dehydrogenase | / | 0.441 | |
1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.441 | |
1y57 | MPZ | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.441 | |
2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.441 | |
2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.441 | |
2cye | COA | Putative thioesterase | / | 0.441 | |
2e8w | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.441 | |
2ejj | SAH | Diphthine synthase | / | 0.441 | |
2mjp | ANP | dITP/XTP pyrophosphatase | 3.6.1.19 | 0.441 | |
2pd8 | FAD | Vivid PAS protein VVD | / | 0.441 | |
2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.441 | |
2rhg | IGP | Tryptophan synthase alpha chain | / | 0.441 | |
2uxu | NAR | HTH-type transcriptional regulator TtgR | / | 0.441 | |
2vwx | 7X4 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.441 | |
3c15 | FOK | Adenylate cyclase type 2 | / | 0.441 | |
3c15 | FOK | Adenylate cyclase type 5 | / | 0.441 | |
3fln | 3FN | Mitogen-activated protein kinase 14 | / | 0.441 | |
3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.441 | |
3igo | ANP | Calmodulin-domain protein kinase 1, putative | / | 0.441 | |
3qbt | GNP | Ras-related protein Rab-8A | / | 0.441 | |
3s2p | PMU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
3slk | NDP | Polyketide synthase extender module 2 | / | 0.441 | |
3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
4boe | CLR | Japanin | / | 0.441 | |
4fg8 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.441 | |
4fki | 09K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
4fv6 | E57 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.441 | |
4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.441 | |
4kxn | 6K6 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | / | 0.441 | |
4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.441 | |
4rqu | NAD | Alcohol dehydrogenase class-P | / | 0.441 | |
4u0s | ADP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.441 | |
4v2g | ITC | Tetracycline repressor protein class D | / | 0.441 | |
4xq9 | NAD | Homospermidine synthase | 2.5.1.44 | 0.441 | |
5itz | GTP | Tubulin alpha-1B chain | / | 0.441 | |
1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
1hnd | COA | 3-oxoacyl-[acyl-carrier-protein] synthase 3 | / | 0.440 | |
1ib6 | NAD | Malate dehydrogenase | / | 0.440 | |
1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
1kqg | MGD | Formate dehydrogenase, nitrate-inducible, major subunit | 1.1.5.6 | 0.440 | |
1lde | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.440 | |
1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.440 | |
1rf7 | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.440 | |
1t2b | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.440 | |
1uy6 | PU3 | Heat shock protein HSP 90-alpha | / | 0.440 | |
2emu | SAH | Diphthine synthase | / | 0.440 | |
2hut | SAH | Diphthine synthase | / | 0.440 | |
2phk | ATP | Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | 2.7.11.19 | 0.440 | |
2vqb | NAP | Putative flavin-containing monooxygenase | / | 0.440 | |
2ydj | YDJ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
2zm1 | KSF | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.440 | |
2zv2 | 609 | Calcium/calmodulin-dependent protein kinase kinase 2 | 2.7.11.17 | 0.440 | |
3ekr | PY9 | Heat shock protein HSP 90-alpha | / | 0.440 | |
3fnh | JPJ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
3hl7 | I47 | Mitogen-activated protein kinase 14 | / | 0.440 | |
3id8 | MRK | Glucokinase | 2.7.1.2 | 0.440 | |
3ime | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.440 | |
3l6j | Z90 | Alr2278 protein | / | 0.440 | |
3lxp | IZA | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.440 | |
3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
3p8z | SAH | Genome polyprotein | 2.1.1.56 | 0.440 | |
3vhu | SNL | Mineralocorticoid receptor | / | 0.440 | |
3zls | 92P | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.440 | |
3zs5 | SB2 | Mitogen-activated protein kinase 14 | / | 0.440 | |
4ap3 | FAD | Steroid monooxygenase | / | 0.440 | |
4azw | ATP | O-antigen chain terminator bifunctional methyltransferase/kinase WbdD | / | 0.440 | |
4elb | 34R | Dihydrofolate reductase | / | 0.440 | |
4fob | 0US | ALK tyrosine kinase receptor | 2.7.10.1 | 0.440 | |
4g8j | THM | Uridine phosphorylase | / | 0.440 | |
4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.440 | |
4jvn | YUG | Estrogen sulfotransferase | 2.8.2.4 | 0.440 | |
4kqw | NAP | Ketol-acid reductoisomerase (NADP(+)) | / | 0.440 | |
4mwh | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.440 | |
5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.440 | |
5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
5jr3 | 4MU | Carminomycin 4-O-methyltransferase DnrK | 2.1.1.292 | 0.440 |