sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3plp | BBA | Cationic trypsin | 3.4.21.4 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3plp | BBA | Cationic trypsin | 3.4.21.4 | 1.000 | |
| 2cji | GSK | Coagulation factor X | 3.4.21.6 | 0.593 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.565 | |
| 4bti | 7R9 | Coagulation factor X | 3.4.21.6 | 0.564 | |
| 2zi2 | 24U | Prothrombin | 3.4.21.5 | 0.562 | |
| 4fue | 7UP | Urokinase-type plasminogen activator | 3.4.21.73 | 0.562 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.557 | |
| 1d4p | BPP | Prothrombin | 3.4.21.5 | 0.556 | |
| 1iqg | XME | Coagulation factor X | 3.4.21.6 | 0.554 | |
| 1ta6 | 177 | Prothrombin | 3.4.21.5 | 0.552 | |
| 1d3p | BT3 | Prothrombin | 3.4.21.5 | 0.549 | |
| 3v0x | ANH | Cationic trypsin | 3.4.21.4 | 0.549 | |
| 2zda | 32U | Prothrombin | 3.4.21.5 | 0.547 | |
| 2g00 | 4QC | Coagulation factor X | 3.4.21.6 | 0.545 | |
| 1c4v | IH2 | Prothrombin | 3.4.21.5 | 0.544 | |
| 1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.543 | |
| 1xm1 | GAH | Prothrombin | 3.4.21.5 | 0.536 | |
| 2jh0 | 701 | Prothrombin | 3.4.21.5 | 0.533 | |
| 1mu8 | CDB | Prothrombin | 3.4.21.5 | 0.531 | |
| 3egk | M18 | Prothrombin | 3.4.21.5 | 0.529 | |
| 4btu | 6XS | Coagulation factor X | 3.4.21.6 | 0.528 | |
| 1mu6 | CDA | Prothrombin | 3.4.21.5 | 0.527 | |
| 1z71 | L17 | Prothrombin | 3.4.21.5 | 0.527 | |
| 1nfy | RTR | Coagulation factor X | 3.4.21.6 | 0.526 | |
| 2a2x | NA9 | Prothrombin | 3.4.21.5 | 0.526 | |
| 3hat | GLY_VAL_ARG_RNG | Prothrombin | 3.4.21.5 | 0.526 | |
| 2jh6 | 894 | Prothrombin | 3.4.21.5 | 0.525 | |
| 2y5g | FJD | Coagulation factor X | 3.4.21.6 | 0.525 | |
| 4ax9 | N5N | Prothrombin | 3.4.21.5 | 0.525 | |
| 1ypg | UIR | Prothrombin | 3.4.21.5 | 0.524 | |
| 1zgi | 382 | Prothrombin | 3.4.21.5 | 0.524 | |
| 2jh5 | 895 | Prothrombin | 3.4.21.5 | 0.524 | |
| 2zhf | 49U | Prothrombin | 3.4.21.5 | 0.524 | |
| 1ype | UIP | Prothrombin | 3.4.21.5 | 0.523 | |
| 1owe | 675 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.521 | |
| 1sqt | UI3 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.521 | |
| 1t4v | 14A | Prothrombin | 3.4.21.5 | 0.521 | |
| 2anm | CDO | Prothrombin | 3.4.21.5 | 0.520 | |
| 3dhk | 23U | Prothrombin | 3.4.21.5 | 0.519 | |
| 2zc9 | 22U | Prothrombin | 3.4.21.5 | 0.518 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.517 | |
| 2viv | VG2 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.516 | |
| 1gj4 | 132 | Prothrombin | 3.4.21.5 | 0.515 | |
| 1riw | OSC | Prothrombin | 3.4.21.5 | 0.514 | |
| 2zfr | 46U | Prothrombin | 3.4.21.5 | 0.514 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.512 | |
| 1vja | 7IN | Urokinase-type plasminogen activator | 3.4.21.73 | 0.511 | |
| 2ziq | 26U | Prothrombin | 3.4.21.5 | 0.511 | |
| 2y5h | Y5H | Coagulation factor X | 3.4.21.6 | 0.509 | |
| 4lxb | 7R9 | Prothrombin | 3.4.21.5 | 0.509 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.509 | |
| 1iqe | XMB | Coagulation factor X | 3.4.21.6 | 0.505 | |
| 3qwc | 98P | Prothrombin | 3.4.21.5 | 0.504 | |
| 3q71 | AR6 | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.502 | |
| 1gmc | PRO_GLY_ALA_TYR | Chymotrypsinogen A | 3.4.21.1 | 0.501 | |
| 2bvs | 2CE | Prothrombin | 3.4.21.5 | 0.499 | |
| 1lqd | CMI | Coagulation factor X | 3.4.21.6 | 0.497 | |
| 1ypl | RA8 | Prothrombin | 3.4.21.5 | 0.497 | |
| 2v3o | I26 | Prothrombin | 3.4.21.5 | 0.497 | |
| 4l4f | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.497 | |
| 1uvs | I11 | Prothrombin | 3.4.21.5 | 0.496 | |
| 3sor | O58 | Coagulation factor XI | 3.4.21.27 | 0.496 | |
| 4mok | FAD | Pyranose 2-oxidase | / | 0.496 | |
| 1o5g | CR9 | Prothrombin | 3.4.21.5 | 0.494 | |
| 2cf8 | ESH | Prothrombin | 3.4.21.5 | 0.494 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.493 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.493 | |
| 2uuk | 897 | Prothrombin | 3.4.21.5 | 0.493 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.493 | |
| 1w13 | SM1 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.492 | |
| 3etd | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.492 | |
| 1c4u | IH1 | Prothrombin | 3.4.21.5 | 0.491 | |
| 1k22 | MEL | Prothrombin | 3.4.21.5 | 0.491 | |
| 3b2s | B2S | Trichothecene 3-O-acetyltransferase | / | 0.491 | |
| 1bcu | PRL | Prothrombin | 3.4.21.5 | 0.490 | |
| 2cn0 | F25 | Prothrombin | 3.4.21.5 | 0.490 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.489 | |
| 4aa4 | QC0 | Mitogen-activated protein kinase 14 | / | 0.489 | |
| 1kts | C24 | Prothrombin | 3.4.21.5 | 0.488 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.488 | |
| 2vh0 | GSI | Coagulation factor X | 3.4.21.6 | 0.488 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.487 | |
| 2cgp | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.486 | |
| 3otf | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | / | 0.486 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.485 | |
| 1ypj | UIB | Prothrombin | 3.4.21.5 | 0.485 | |
| 4opi | FDA | Conserved Archaeal protein | / | 0.485 | |
| 1kev | NDP | NADP-dependent isopropanol dehydrogenase | 1.1.1.80 | 0.484 | |
| 4kgk | GTP | Uncharacterized protein | / | 0.484 | |
| 1ny2 | ARG_PRO_PRO_GLY | Prothrombin | 3.4.21.5 | 0.483 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.483 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.482 | |
| 1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.482 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.482 | |
| 5c77 | SAH | Protein arginine N-methyltransferase SFM1 | / | 0.482 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.481 | |
| 4u0m | ATP | Cyclic GMP-AMP synthase | / | 0.481 | |
| 1ezv | UQ6 | Cytochrome b | / | 0.480 | |
| 1equ | EQI | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.479 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.479 | |
| 2xbx | RR8 | Coagulation factor X | 3.4.21.6 | 0.479 | |
| 3hk1 | B64 | Fatty acid-binding protein, adipocyte | / | 0.479 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.479 | |
| 3o0q | ADN | Vitamin B12-dependent ribonucleotide reductase | / | 0.479 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.479 | |
| 4eu9 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.479 | |
| 1c5n | ESI | Prothrombin | 3.4.21.5 | 0.478 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.478 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.478 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.477 | |
| 4loy | 6XS | Prothrombin | 3.4.21.5 | 0.477 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.476 | |
| 2a1o | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.475 | |
| 3lsi | FAD | Pyranose 2-oxidase | / | 0.475 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.474 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 4bqh | 9VU | UDP-N-acetylglucosamine pyrophosphorylase, putative | / | 0.474 | |
| 4fuj | 1U9 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.474 | |
| 4nd2 | A3D | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.474 | |
| 4rn6 | 15U | Prothrombin | 3.4.21.5 | 0.474 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.473 | |
| 2eud | GCQ | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.473 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.473 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.473 | |
| 4h4e | 10G | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase | / | 0.473 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.472 | |
| 1fwk | ADP | Homoserine kinase | 2.7.1.39 | 0.472 | |
| 2v3w | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.472 | |
| 3biv | 11U | Prothrombin | 3.4.21.5 | 0.472 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.472 | |
| 4fub | 4UP | Urokinase-type plasminogen activator | 3.4.21.73 | 0.472 | |
| 4fuf | 8UP | Urokinase-type plasminogen activator | 3.4.21.73 | 0.472 | |
| 4i8z | G08 | Gag-Pol polyprotein | 3.4.23.16 | 0.472 | |
| 4c72 | TLG | 3-oxoacyl-ACP synthase | / | 0.471 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.471 | |
| 4m49 | 22Y | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.471 | |
| 5dp2 | NAP | CurF | / | 0.471 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.470 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.470 | |
| 3tb9 | CDP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.470 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.469 | |
| 2xby | 63C | Coagulation factor X | 3.4.21.6 | 0.469 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.469 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.468 | |
| 1v2h | GUN | Purine nucleoside phosphorylase | 2.4.2.1 | 0.468 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.468 | |
| 2zgy | GDP | Plasmid segregation protein ParM | / | 0.468 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.468 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.468 | |
| 3vy2 | FMN | FMN-binding protein | / | 0.468 | |
| 3w8d | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.468 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.468 | |
| 4kp5 | E1F | Carbonic anhydrase 12 | 4.2.1.1 | 0.468 | |
| 1kqn | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.467 | |
| 1pjc | NAD | Alanine dehydrogenase | / | 0.467 | |
| 2ekl | NAD | D-3-phosphoglycerate dehydrogenase | / | 0.467 | |
| 2vpr | TDC | Tetracycline repressor protein class H | / | 0.467 | |
| 3kqe | LGM | Coagulation factor X | 3.4.21.6 | 0.467 | |
| 3o0o | 5AD | Vitamin B12-dependent ribonucleotide reductase | / | 0.467 | |
| 4k28 | NAD | Shikimate dehydrogenase family protein | / | 0.467 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.467 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 1ra3 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 1sl3 | 170 | Prothrombin | 3.4.21.5 | 0.466 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.466 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.466 | |
| 1p4a | PCP | Pur operon repressor | / | 0.465 | |
| 1tde | FAD | Thioredoxin reductase | 1.8.1.9 | 0.465 | |
| 2ab8 | MTP | Adenosine kinase | 2.7.1.20 | 0.465 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.465 | |
| 3ndc | SAH | Precorrin-4 C(11)-methyltransferase | 2.1.1.133 | 0.465 | |
| 3rpe | FAD | Putative modulator of drug activity | / | 0.465 | |
| 1b8u | NAD | Malate dehydrogenase | / | 0.464 | |
| 1hku | NAD | C-terminal-binding protein 1 | 1.1.1 | 0.464 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.464 | |
| 1yqz | COA | Coenzyme A disulfide reductase | / | 0.464 | |
| 2bxm | IMN | Serum albumin | / | 0.464 | |
| 2jkv | NAP | 6-phosphogluconate dehydrogenase, decarboxylating | 1.1.1.44 | 0.464 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.464 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.464 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.464 | |
| 4d8n | 0HM | Kallikrein-6 | 3.4.21 | 0.464 | |
| 1mq6 | XLD | Coagulation factor X | 3.4.21.6 | 0.463 | |
| 1ppj | ANY | Cytochrome b | / | 0.463 | |
| 2bok | 784 | Coagulation factor X | 3.4.21.6 | 0.463 | |
| 2qrq | S13 | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.463 | |
| 2zeb | 11M | Tryptase alpha/beta-1 | 3.4.21.59 | 0.463 | |
| 3a3b | RBF | Lumazine protein | / | 0.463 | |
| 3gvh | NAD | Malate dehydrogenase | / | 0.463 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.463 | |
| 4jc5 | 1K5 | Stimulator of interferon genes protein | / | 0.463 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.463 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 1kc1 | NDP | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.462 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.462 | |
| 1oyt | FSN | Prothrombin | 3.4.21.5 | 0.462 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.462 | |
| 1ta2 | 176 | Prothrombin | 3.4.21.5 | 0.462 | |
| 1ual | SAH | tRNA (guanine-N(1)-)-methyltransferase | 2.1.1.228 | 0.462 | |
| 2cf9 | 348 | Prothrombin | 3.4.21.5 | 0.462 | |
| 3kb6 | NAD | D-lactate dehydrogenase | / | 0.462 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.462 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.462 | |
| 4cr8 | NAD | N-acylmannosamine 1-dehydrogenase | 1.1.1.233 | 0.462 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.461 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.461 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.461 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.461 | |
| 2b37 | 8PS | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.461 | |
| 2c4f | GIL | Coagulation factor VII | 3.4.21.21 | 0.461 | |
| 2ien | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.461 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.461 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.461 | |
| 3iqg | ASN_TRP_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.461 | |
| 3o26 | NDP | Salutaridine reductase | / | 0.461 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.461 | |
| 4jxr | ACO | Acetyltransferase | / | 0.461 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.461 | |
| 5c8w | PCG | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.461 | |
| 5cyo | GDP | Septin-9 | / | 0.461 | |
| 1d7a | AIR | N5-carboxyaminoimidazole ribonucleotide mutase | / | 0.460 | |
| 1tww | HH2 | Dihydropteroate synthase | / | 0.460 | |
| 1y7l | ASN_LEU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.460 | |
| 1yrc | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.460 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.460 | |
| 4fui | UI3 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.460 | |
| 4i02 | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.460 | |
| 4tvb | NAD | Homospermidine synthase | 2.5.1.44 | 0.460 | |
| 1jvd | UD1 | UDP-N-acetylhexosamine pyrophosphorylase | 2.7.7.23 | 0.459 | |
| 2tps | TPS | Thiamine-phosphate synthase | / | 0.459 | |
| 3kqb | LGJ | Coagulation factor X | 3.4.21.6 | 0.459 | |
| 3r0i | C0K | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.459 | |
| 4ayv | 9MQ | Prothrombin | 3.4.21.5 | 0.459 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.459 | |
| 4udr | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.459 | |
| 2abj | CBC | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.458 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.458 | |
| 2qn3 | F55 | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.458 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.458 | |
| 3lzs | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.458 | |
| 4jwh | SAH | tRNA (guanine(9)-N1)-methyltransferase | / | 0.458 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.458 | |
| 5dw6 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.458 | |
| 1dxo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.457 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.457 | |
| 1hdg | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.457 | |
| 1u8v | FAD | 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase | / | 0.457 | |
| 1uam | SAH | tRNA (guanine-N(1)-)-methyltransferase | 2.1.1.228 | 0.457 | |
| 2hu2 | NAD | C-terminal binding protein 1 | / | 0.457 | |
| 2j34 | GS6 | Coagulation factor X | 3.4.21.6 | 0.457 | |
| 2xfs | J01 | Uncharacterized protein | / | 0.457 | |
| 2znp | K55 | Peroxisome proliferator-activated receptor delta | / | 0.457 | |
| 3bbd | SAH | Ribosomal RNA small subunit methyltransferase Nep1 | 2.1.1 | 0.457 | |
| 3kji | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.457 | |
| 4c9o | CAM | Cytochrome P450 | / | 0.457 | |
| 4dja | FAD | (6-4) photolyase | / | 0.457 | |
| 4eu8 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.457 | |
| 4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.457 | |
| 4n3c | UD1 | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.457 | |
| 4uoc | NCN | CinA-like protein | / | 0.457 | |
| 4xbo | SAH | tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ | 2.1.1.200 | 0.457 | |
| 1c1d | NAI | Phenylalanine dehydrogenase | / | 0.456 | |
| 1d7l | RFL | p-hydroxybenzoate hydroxylase | / | 0.456 | |
| 2c1b | CQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.456 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.456 | |
| 2h94 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.456 | |
| 2ii6 | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.456 | |
| 2nni | MTK | Cytochrome P450 2C8 | / | 0.456 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.456 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 3aut | NAI | Glucose 1-dehydrogenase 4 | 1.1.1.47 | 0.456 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.456 | |
| 3tne | RIT | Candidapepsin-1 | 3.4.23.24 | 0.456 | |
| 3wb2 | YGP | Uncharacterized protein MJ0488 | / | 0.456 | |
| 4blr | UTP | NTPase P4 | / | 0.456 | |
| 4iql | FMN | Enoyl-(Acyl-carrier-protein) reductase II | / | 0.456 | |
| 4rvd | SAM | D-mycarose 3-C-methyltransferase | / | 0.456 | |
| 4xj4 | 3AT | Cyclic GMP-AMP synthase | / | 0.456 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.456 | |
| 1h74 | ADP | Homoserine kinase | 2.7.1.39 | 0.455 | |
| 1nhh | ANP | DNA mismatch repair protein MutL | / | 0.455 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.455 | |
| 2fut | H1S | Heparin and heparin-sulfate lyase | / | 0.455 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.455 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.455 | |
| 3bg7 | FAD | Pyranose 2-oxidase | / | 0.455 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.455 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.455 | |
| 3q33 | ACO | Histone acetyltransferase RTT109 | 2.3.1.48 | 0.455 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.455 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.455 | |
| 4h4u | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.455 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.455 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.454 | |
| 1dxy | NAD | D-2-hydroxyisocaproate dehydrogenase | 1.1.1 | 0.454 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.454 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.454 | |
| 1rz0 | FAD | Phenol 2-hydroxylase component B | / | 0.454 | |
| 2c31 | TZD | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.454 | |
| 2ome | NAD | C-terminal-binding protein 2 | / | 0.454 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.454 | |
| 2x0i | NAI | Malate dehydrogenase | / | 0.454 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.454 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.454 | |
| 5a9s | NAP | Putative dehydrogenase | / | 0.454 | |
| 1cs4 | FOK | Adenylate cyclase type 2 | / | 0.453 | |
| 1cs4 | FOK | Adenylate cyclase type 5 | / | 0.453 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 2dv5 | SAH | Diphthine synthase | / | 0.453 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.453 | |
| 2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.453 | |
| 2op9 | WR1 | Orf1ab polyprotein | / | 0.453 | |
| 2y82 | 930 | Coagulation factor X | 3.4.21.6 | 0.453 | |
| 3daa | PDD | D-alanine aminotransferase | 2.6.1.21 | 0.453 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.453 | |
| 4acu | QN7 | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.453 | |
| 4ddh | MS0 | Pantothenate synthetase | 6.3.2.1 | 0.453 | |
| 4jb1 | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.453 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.452 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.452 | |
| 1hbv | GAN | Gag-Pol polyprotein | / | 0.452 | |
| 1o0d | 163 | Prothrombin | 3.4.21.5 | 0.452 | |
| 1ra8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.452 | |
| 2d8a | NAD | L-threonine 3-dehydrogenase | / | 0.452 | |
| 2e15 | SAH | Diphthine synthase | / | 0.452 | |
| 2hfu | MEV | Mevalonate kinase | / | 0.452 | |
| 2owk | SAH | Diphthine synthase | / | 0.452 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.452 | |
| 3qdz | PRO_ALA_PRO_ARG | Prothrombin | 3.4.21.5 | 0.452 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 4m5p | FMN | NADPH dehydrogenase | / | 0.452 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.452 | |
| 4qai | FMN | NADPH dehydrogenase | / | 0.452 | |
| 4x3m | ADN | RNA 2'-O ribose methyltransferase | / | 0.452 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.451 | |
| 1dhi | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.451 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1t32 | OHH | Cathepsin G | 3.4.21.20 | 0.451 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.451 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.451 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.451 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.451 | |
| 2oeg | UPG | UDP-glucose pyrophosphorylase | / | 0.451 | |
| 2uyi | ADP | Kinesin-like protein KIF11 | / | 0.451 | |
| 2v13 | C40 | Renin | 3.4.23.15 | 0.451 | |
| 3awh | FMN | FMN-binding protein | / | 0.451 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.451 | |
| 4l6g | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.451 | |
| 4yvj | SFG | tRNA (guanine-N(1)-)-methyltransferase | 2.1.1.228 | 0.451 | |
| 1g4t | FTP | Thiamine-phosphate synthase | / | 0.450 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.450 | |
| 1qbq | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.450 | |
| 1qbq | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.450 | |
| 1rd7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.450 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.450 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.450 | |
| 3ajr | NAD | NDP-sugar epimerase | / | 0.450 | |
| 3bv2 | P38 | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 3ipk | PMS | Surface protein adhesin | / | 0.450 | |
| 3kjm | 245 | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.450 | |
| 3mt8 | 17T | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.450 | |
| 4im0 | 1FV | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.450 | |
| 4r1l | ADP | Phenylacetate-coenzyme A ligase | / | 0.450 | |
| 4rf2 | NAP | NADPH dependent R-specific alcohol dehydrogenase | / | 0.450 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 5e8j | SAH | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.450 | |
| 1ep1 | FMN | Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit | 1.3.1.14 | 0.449 | |
| 1f92 | UKP | Urokinase-type plasminogen activator | 3.4.21.73 | 0.449 | |
| 1gc5 | ADP | ADP-dependent glucokinase | 2.7.1.147 | 0.449 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 2j07 | HDF | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.449 | |
| 2ji6 | TPW | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.449 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.449 | |
| 2uz1 | TPP | Benzaldehyde lyase | / | 0.449 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.449 | |
| 2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.449 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.449 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.449 | |
| 3pce | 3HP | Protocatechuate 3,4-dioxygenase alpha chain | 1.13.11.3 | 0.449 | |
| 3pce | 3HP | Protocatechuate 3,4-dioxygenase beta chain | 1.13.11.3 | 0.449 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.449 | |
| 3pvc | FAD | tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC | / | 0.449 | |
| 3rqq | BA3 | ADP-dependent (S)-NAD(P)H-hydrate dehydratase | / | 0.449 | |
| 3zho | FMN | NAD(P)H dehydrogenase (quinone) | / | 0.449 | |
| 4c04 | SFG | Protein arginine N-methyltransferase 6 | / | 0.449 | |
| 4r81 | FMN | Predicted NADH dehydrogenase | / | 0.449 | |
| 1b5e | DCM | Deoxycytidylate 5-hydroxymethyltransferase | 2.1.2.8 | 0.448 | |
| 1cnf | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.448 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.448 | |
| 1kfb | IGP | Tryptophan synthase alpha chain | / | 0.448 | |
| 1l4m | NCN | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.448 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.448 | |
| 2a1m | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 2e17 | SAH | Diphthine synthase | / | 0.448 | |
| 2ed4 | NAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.448 | |
| 2fr1 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.448 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.448 | |
| 3doc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.448 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3eks | CY9 | Actin-5C | / | 0.448 | |
| 3lsm | SFD | Pyranose 2-oxidase | / | 0.448 | |
| 3wsw | NAD | L-lactate dehydrogenase | / | 0.448 | |
| 4a0r | DTB | Bifunctional dethiobiotin synthetase/7,8-diamino-pelargonic acid aminotransferase, mitochondrial | 6.3.3.3 | 0.448 | |
| 4lhv | GDP | Ras-related protein Rab-8A | / | 0.448 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.448 | |
| 4rcv | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.448 | |
| 4ubv | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.448 | |
| 5itz | GTP | Tubulin alpha-1B chain | / | 0.448 | |
| 1i6x | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.447 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.447 | |
| 2bro | DF2 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 2gz7 | D3F | Orf1a polyprotein | / | 0.447 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.447 | |
| 2y0j | AXC | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 3cty | FAD | Probable thioredoxin reductase | / | 0.447 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3etg | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.447 | |
| 3ivg | FG5 | Pantothenate synthetase | 6.3.2.1 | 0.447 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.447 | |
| 3o15 | 3NM | Thiamine-phosphate synthase | / | 0.447 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.447 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 4r1f | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.447 | |
| 4u0m | GTP | Cyclic GMP-AMP synthase | / | 0.447 | |
| 1a8r | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.446 | |
| 1c4y | IH3 | Prothrombin | 3.4.21.5 | 0.446 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1qy8 | RDI | Endoplasmin | / | 0.446 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 2bfq | AR6 | [Protein ADP-ribosylglutamate] hydrolase AF_1521 | 3.2.2 | 0.446 | |
| 2idk | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.446 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.446 | |
| 2zaw | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 2zhw | 12U | Prothrombin | 3.4.21.5 | 0.446 | |
| 3aw9 | NAD | NAD-dependent epimerase/dehydratase | / | 0.446 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.446 | |
| 3fql | 79Z | Genome polyprotein | 2.7.7.48 | 0.446 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.446 | |
| 3i28 | 34N | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.446 | |
| 3mkn | DNB | Pyrimidine-specific ribonucleoside hydrolase RihB | / | 0.446 | |
| 3n4k | SAH | tRNA (cytidine(34)-2'-O)-methyltransferase | / | 0.446 | |
| 3p2o | NAD | Bifunctional protein FolD | / | 0.446 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 4acx | S8Z | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 4l4x | NDP | AmphI | / | 0.446 | |
| 1a9z | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.445 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.445 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.445 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.445 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.445 | |
| 1r2j | FAD | FkbI | / | 0.445 | |
| 2ag1 | TPP | Benzaldehyde lyase | / | 0.445 | |
| 2bi8 | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.445 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.445 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.445 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.445 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.445 | |
| 2rkv | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.445 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.445 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.445 | |
| 3hgo | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.445 | |
| 3ik6 | HCZ | Glutamate receptor 2 | / | 0.445 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.445 | |
| 3s3v | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 4bkq | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.445 | |
| 4mcd | 22L | tRNA (guanine-N(1)-)-methyltransferase | 2.1.1.228 | 0.445 | |
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 0.445 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.445 | |
| 4pzk | SAH | Putative tRNA (cytidine(34)-2'-O)-methyltransferase | / | 0.445 | |
| 4qq3 | XMP | Inosine-5'-monophosphate dehydrogenase | / | 0.445 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.444 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.444 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.444 | |
| 1u2y | GOX | Pancreatic alpha-amylase | / | 0.444 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.444 | |
| 1vik | BAY | Gag-Pol polyprotein | / | 0.444 | |
| 2hsd | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.444 | |
| 2izh | BTN | Streptavidin | / | 0.444 | |
| 2z4y | 252 | Geranylgeranyl pyrophosphate synthase | / | 0.444 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.444 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.444 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.444 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.444 | |
| 3isj | A8D | Pantothenate synthetase | 6.3.2.1 | 0.444 | |
| 3nd1 | SAH | Precorrin-6A synthase (Deacetylating) | / | 0.444 | |
| 3toz | NAD | Shikimate dehydrogenase (NADP(+)) | / | 0.444 | |
| 4a6n | FAD | TetX family tetracycline inactivation enzyme | / | 0.444 | |
| 4die | C5P | Cytidylate kinase | / | 0.444 | |
| 4e32 | DWN | Methyltransferase | / | 0.444 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.444 | |
| 4i9n | 1E5 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.444 | |
| 4xb2 | NDP | 319aa long hypothetical homoserine dehydrogenase | / | 0.444 | |
| 1a59 | COA | 2-methylcitrate synthase | / | 0.443 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.443 | |
| 1h65 | GDP | Translocase of chloroplast 34 | 3.6.5 | 0.443 | |
| 1jhq | PMO | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.443 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.443 | |
| 1lrj | UD1 | UDP-glucose 4-epimerase | 5.1.3.2 | 0.443 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.443 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.443 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 2cmj | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.443 | |
| 2ek3 | SAH | Diphthine synthase | / | 0.443 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.443 | |
| 2wsb | NAD | Galactitol dehydrogenase | / | 0.443 | |
| 2yy7 | NAD | L-threonine dehydrogenase | / | 0.443 | |
| 2z0y | SAM | Ribosomal RNA small subunit methyltransferase E | / | 0.443 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 3dhc | CYK | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.443 | |
| 3dzi | RGT | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.443 | |
| 3f68 | 91U | Prothrombin | 3.4.21.5 | 0.443 | |
| 3gvi | ADP | Malate dehydrogenase | / | 0.443 | |
| 3ijr | NAD | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.443 | |
| 3ooi | SAM | Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific | 2.1.1.43 | 0.443 | |
| 3t2v | KKJ | Peptidoglycan recognition protein 1 | / | 0.443 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.443 | |
| 3wbf | NAP | Meso-diaminopimelate D-dehydrogenase | / | 0.443 | |
| 4emt | C2E | Stimulator of interferon genes protein | / | 0.443 | |
| 4ho6 | UTP | Glucose-1-phosphate thymidylyltransferase | / | 0.443 | |
| 4l4a | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 4lcj | NAD | C-terminal-binding protein 2 | / | 0.443 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.442 | |
| 1e5q | NDP | Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] | 1.5.1.10 | 0.442 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.442 | |
| 1kvk | ATP | Mevalonate kinase | 2.7.1.36 | 0.442 | |
| 1n5d | NDP | Carbonyl reductase [NADPH] 1 | / | 0.442 | |
| 1owi | 426 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.442 | |
| 1phh | FAD | p-hydroxybenzoate hydroxylase | / | 0.442 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.442 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 1u54 | ACP | Activated CDC42 kinase 1 | / | 0.442 | |
| 2b82 | ADN | Class B acid phosphatase | 3.1.3.2 | 0.442 | |
| 2bgm | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.442 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.442 | |
| 2ibz | UQ6 | Cytochrome b | / | 0.442 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.442 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.442 | |
| 3d8v | UD1 | Bifunctional protein GlmU | / | 0.442 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.442 | |
| 3sj7 | NDP | 3-oxoacyl-(Acyl-carrier-protein) reductase, putative | / | 0.442 | |
| 3wag | TYD | Glycosyltransferase | / | 0.442 | |
| 4btt | VYR | Coagulation factor X | 3.4.21.6 | 0.442 | |
| 4gll | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.442 | |
| 4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.442 | |
| 4rr8 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.442 | |
| 4z4p | SAH | Histone-lysine N-methyltransferase 2D | 2.1.1.43 | 0.442 | |
| 1dgm | ADN | Adenosine kinase | 2.7.1.20 | 0.441 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 1orh | SAH | Protein arginine N-methyltransferase 1 | / | 0.441 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.441 | |
| 2gcg | NDP | Glyoxylate reductase/hydroxypyruvate reductase | 1.1.1.79 | 0.441 | |
| 2h9i | EAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.441 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.441 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.441 | |
| 2vnj | FAD | NADPH:ferredoxin reductase | / | 0.441 | |
| 2w14 | WR2 | Snake venom metalloproteinase BaP1 | 3.4.24 | 0.441 | |
| 3anl | SYC | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.441 | |
| 3clb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.441 | |
| 3dk1 | G05 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 3h06 | VBP | Glutamate receptor 2 | / | 0.441 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 3lsh | FAD | Pyranose 2-oxidase | / | 0.441 | |
| 3lxi | CAM | Cytochrome P450 | / | 0.441 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.441 | |
| 3tjl | FMN | NADPH dehydrogenase | / | 0.441 | |
| 3upf | 0BU | Polyprotein | / | 0.441 | |
| 3wrh | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.441 | |
| 4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.441 | |
| 4geb | 0LD | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.441 | |
| 4kl9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4nvk | 2NY | Peroxidase | / | 0.441 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.441 | |
| 1cjv | FOK | Adenylate cyclase type 2 | / | 0.440 | |
| 1cjv | FOK | Adenylate cyclase type 5 | / | 0.440 | |
| 1h62 | ANB | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 1o0s | NAI | NAD-dependent malic enzyme, mitochondrial | 1.1.1.38 | 0.440 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.440 | |
| 1rp0 | AHZ | Thiamine thiazole synthase, chloroplastic | / | 0.440 | |
| 1tl7 | FOK | Adenylate cyclase type 2 | / | 0.440 | |
| 1tl7 | FOK | Adenylate cyclase type 5 | / | 0.440 | |
| 1v45 | 3DG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 2f3r | G5P | Guanylate kinase | 2.7.4.8 | 0.440 | |
| 2fa3 | ACO | Hydroxymethylglutaryl-CoA synthase | / | 0.440 | |
| 2hr8 | SAH | Diphthine synthase | / | 0.440 | |
| 2jla | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.440 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.440 | |
| 2yex | YEX | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.440 | |
| 3cz7 | ACO | Histone acetyltransferase RTT109 | 2.3.1.48 | 0.440 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.440 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 3lcj | COA | Phosphopantetheine adenylyltransferase | / | 0.440 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 3q1f | YPP | Beta-lactamase | / | 0.440 | |
| 3rfx | NAD | Uronate dehydrogenase | / | 0.440 | |
| 4ajj | 88R | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.440 | |
| 4e2b | FMN | Dehydrogenase | / | 0.440 | |
| 4u7w | NDP | MxaA | / | 0.440 | |
| 5c4n | NAP | Precorrin-6A reductase | 1.3.1.54 | 0.440 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.440 |