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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3frfXCFDihydrofolate reductase1.5.1.3

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3frfXCFDihydrofolate reductase1.5.1.31.000
3frdDHFDihydrofolate reductase1.5.1.30.684
3fywXCFDihydrofolate reductase1.5.1.30.648
4xe606UDihydrofolate reductase1.5.1.30.648
2w9gTOPDihydrofolate reductase1.5.1.30.646
3fy9XCFDihydrofolate reductase1.5.1.30.646
3fraI2HDihydrofolate reductase1.5.1.30.640
3srrQ20Dihydrofolate reductase1.5.1.30.619
3m08RARDihydrofolate reductase1.5.1.30.613
3srqQ19Dihydrofolate reductase1.5.1.30.610
3srwQ27Dihydrofolate reductase1.5.1.30.610
4fgh0U6Dihydrofolate reductase1.5.1.30.600
3fy8XCFDihydrofolate reductase1.5.1.30.599
3sruQ26Dihydrofolate reductase1.5.1.30.598
2w3vTOPDihydrofolate reductase/0.590
3fyvXCFDihydrofolate reductase1.5.1.30.585
3sh25DRDihydrofolate reductase1.5.1.30.583
3jw5TOPDihydrofolate reductase/0.578
4fgg0U5Dihydrofolate reductase1.5.1.30.578
3sa16DRDihydrofolate reductase/0.576
4nx6FOLDihydrofolate reductase1.5.1.30.576
3qyoQ24Dihydrofolate reductase1.5.1.30.575
3dfrMTXDihydrofolate reductase1.5.1.30.572
3sgy06WDihydrofolate reductase1.5.1.30.572
3freTOPDihydrofolate reductase1.5.1.30.570
3iro2CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.570
3jwcEKBDihydrofolate reductase/0.569
3datMTXDihydrofolate reductase/0.568
3tq9MTXDihydrofolate reductase/0.565
1aoeGW3Dihydrofolate reductase1.5.1.30.563
1qzfFOLBifunctional dihydrofolate reductase-thymidylate synthase/0.563
1dg5TOPDihydrofolate reductase1.5.1.30.562
3qfxCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.559
1klkPMDDihydrofolate reductase1.5.1.30.557
1rx3MTXDihydrofolate reductase1.5.1.30.556
3invC50Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.556
3dgaRJ1Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.555
3ia4MTXDihydrofolate reductase/0.555
2fzhDH1Dihydrofolate reductase1.5.1.30.554
1dajMOTDihydrofolate reductase1.5.1.30.551
3eek53SUncharacterized protein/0.551
1cd2FOLDihydrofolate reductase1.5.1.30.550
2zzaFOLDihydrofolate reductase/0.550
3qlzQLZUncharacterized protein/0.550
3ix9MTXDihydrofolate reductase1.5.1.30.549
3jwm5WBDihydrofolate reductase/0.546
3cseN22Uncharacterized protein/0.544
3srsM23Dihydrofolate reductase1.5.1.30.544
3tqbFOLDihydrofolate reductase/0.543
1m78CLZDihydrofolate reductase1.5.1.30.542
3td8D2RDihydrofolate reductase1.5.1.30.542
3um61CYBifunctional dihydrofolate reductase-thymidylate synthase/0.541
4kjjFOLDihydrofolate reductase1.5.1.30.541
4h9614QDihydrofolate reductase1.5.1.30.540
1ia1TQ3Dihydrofolate reductase1.5.1.30.539
4ixgIXGDihydrofolate reductase1.5.1.30.539
3irn1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.538
1df7MTXDihydrofolate reductase1.5.1.30.537
2qk8MTXDihydrofolate reductase/0.535
1vj3TABDihydrofolate reductase1.5.1.30.533
4nx7FOLDihydrofolate reductase1.5.1.30.533
3cd2MTXDihydrofolate reductase1.5.1.30.532
3qg2CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.532
3qlrQLRDihydrofolate reductase1.5.1.30.532
2fziDH3Dihydrofolate reductase1.5.1.30.531
3jw3TOPDihydrofolate reductase/0.530
4elg52JDihydrofolate reductase/0.530
4x5gFOLDihydrofolate reductase1.5.1.30.530
3qls55VDihydrofolate reductase1.5.1.30.529
3fl8RARDihydrofolate reductase/0.528
1j3kWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.525
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.525
3um5CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.524
3kjsDQ1Bifunctional dihydrofolate reductase-thymidylate synthase/0.522
3eej53RUncharacterized protein/0.521
4elf35IDihydrofolate reductase/0.521
1dg7WRBDihydrofolate reductase1.5.1.30.520
4h9814QUncharacterized protein/0.520
4m2xTMQDihydrofolate reductase1.5.1.30.519
3qlxQLRUncharacterized protein/0.517
3eel53TUncharacterized protein/0.516
2bl9CP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.515
3fl9TOPDihydrofolate reductase/0.515
1ly3COGDihydrofolate reductase1.5.1.30.513
3i8aN22Dihydrofolate reductase1.5.1.30.513
3dauMTXDihydrofolate reductase1.5.1.30.512
4elb34SDihydrofolate reductase/0.512
3qly55VUncharacterized protein/0.511
3m09RARDihydrofolate reductase1.5.1.30.510
1m7aMQUDihydrofolate reductase1.5.1.30.509
3dg8RJ6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.509
3sai9DRDihydrofolate reductase/0.509
1jomFFODihydrofolate reductase1.5.1.30.507
1ia3TQ5Dihydrofolate reductase1.5.1.30.506
4ixfIXFDihydrofolate reductase1.5.1.30.506
2blaCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.505
2vg7NNIGag-Pol polyprotein2.7.7.490.505
1hfqMOTDihydrofolate reductase1.5.1.30.504
4ixeIXEDihydrofolate reductase1.5.1.30.504
4p66MTXDihydrofolate reductase/0.504
5k2aZMAAdenosine receptor A2a/0.502
2o4jVD4Vitamin D3 receptor/0.501
4g8zTOPDihydrofolate reductase1.5.1.30.500
4elh53IDihydrofolate reductase/0.499
1j3iWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.498
1ia4TQ6Dihydrofolate reductase1.5.1.30.497
1j3jCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.497
2cd2FOLDihydrofolate reductase1.5.1.30.497
4g1z0VPVitamin D3 receptor A/0.497
3eem53VUncharacterized protein/0.496
4ele31IDihydrofolate reductase/0.496
1disBDMDihydrofolate reductase1.5.1.30.495
1kmsLIHDihydrofolate reductase1.5.1.30.495
1s0zEB1Vitamin D3 receptor/0.495
1txiTX5Vitamin D3 receptor/0.495
2hb7O1CVitamin D3 receptor/0.495
1m79MQ1Dihydrofolate reductase1.5.1.30.494
1rg7MTXDihydrofolate reductase1.5.1.30.494
2opqHBQGag-Pol polyprotein2.7.7.490.494
1ly4COQDihydrofolate reductase1.5.1.30.493
2o4rVD5Vitamin D3 receptor/0.493
3vt5YI2Vitamin D3 receptor/0.492
4h9753SDihydrofolate reductase1.5.1.30.492
1s19MC9Vitamin D3 receptor/0.491
2hasC3OVitamin D3 receptor/0.491
3qlwN22Dihydrofolate reductase1.5.1.30.491
2hamC33Vitamin D3 receptor/0.490
3sqyQ11Dihydrofolate reductase1.5.1.30.490
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.490
1rk3VDXVitamin D3 receptor/0.488
3x0a5GPPhosphatidylinositol 5-phosphate 4-kinase type-2 beta2.7.1.1490.488
5k2cZMAAdenosine receptor A2a/0.488
3nj0PYVAbscisic acid receptor PYL2/0.487
4ddrMMVDihydrofolate reductase1.5.1.30.487
4eilFOLBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.487
4muw2F4cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.487
1ddsMTXDihydrofolate reductase1.5.1.30.486
2hb8MVDVitamin D3 receptor/0.486
3csdEMOPutative ketoacyl reductase1.3.10.486
3d80Q22Dihydrofolate reductase1.5.1.30.486
3kpzZNEVitamin D3 receptor/0.486
3qgtCP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.486
4g1y0VOVitamin D3 receptor A/0.486
4ge40KEKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.486
4hf415HcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.486
3a783EVVitamin D3 receptor/0.485
3lfcZ86Mitogen-activated protein kinase 14/0.485
4x5fFOLDihydrofolate reductase1.5.1.30.485
1e26GPBDihydrofolate reductase1.5.1.30.484
2hc4VDXVitamin D3 receptor A/0.484
3tq8TOPDihydrofolate reductase/0.484
3vt3VDXVitamin D3 receptor/0.484
4jlj1NMDeoxycytidine kinase2.7.1.740.484
1ia2TQ4Dihydrofolate reductase1.5.1.30.483
2qbnCAMCamphor 5-monooxygenase1.14.15.10.483
3gyf51PDihydrofolate reductase1.5.1.30.483
4dphP65Bifunctional dihydrofolate reductase-thymidylate synthase/0.483
4g20484Vitamin D3 receptor A/0.483
1dr3TAPDihydrofolate reductase1.5.1.30.482
1ie8KH1Vitamin D3 receptor/0.482
2blcCP7Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.482
2x7hPFNProstaglandin reductase 310.482
2ydvNECAdenosine receptor A2a/0.482
3gieACPSensor histidine kinase DesK2.7.13.30.482
1d3hA26Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.481
1s3yTQTDihydrofolate reductase1.5.1.30.481
2zlcVDXVitamin D3 receptor/0.481
3vt8YI3Vitamin D3 receptor/0.481
4dfrMTXDihydrofolate reductase1.5.1.30.481
4ezj0SCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.481
4g95OAGDihydrofolate reductase1.5.1.30.481
4m6l21VDihydrofolate reductase1.5.1.30.481
1ddrMTXDihydrofolate reductase1.5.1.30.480
1rkhVD2Vitamin D3 receptor/0.480
2harOCCVitamin D3 receptor/0.480
3nrrD16Bifunctional dihydrofolate reductase-thymidylate synthase/0.480
3ctj320Hepatocyte growth factor receptor2.7.10.10.479
3gwfFADCyclohexanone monooxygenase/0.479
3pce3HPProtocatechuate 3,4-dioxygenase alpha chain1.13.11.30.479
3pce3HPProtocatechuate 3,4-dioxygenase beta chain1.13.11.30.479
3sa27DRDihydrofolate reductase/0.479
4m7vRARDihydrofolate reductase/0.479
1osvCHCBile acid receptor/0.478
2bbqPFGThymidylate synthase/0.478
2drcMTXDihydrofolate reductase1.5.1.30.478
3clbTMQBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.478
3oafOAGDihydrofolate reductase1.5.1.30.478
5cccDDFDihydrofolate reductase1.5.1.30.478
1db1VDXVitamin D3 receptor/0.477
2blbCP7Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.477
3drcMTXDihydrofolate reductase1.5.1.30.477
3mec65BGag-Pol polyprotein2.7.7.490.477
3th8TH9Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.477
3um81CYBifunctional dihydrofolate reductase-thymidylate synthase/0.477
3up3XCAaceDAF-12/0.477
4rrxLURProstaglandin G/H synthase 21.14.99.10.477
1enyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.476
1jolFFODihydrofolate reductase1.5.1.30.476
1re7FOLDihydrofolate reductase1.5.1.30.476
1uaeUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.476
4fhh0U3Vitamin D3 receptor A/0.476
1lsjNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.475
2cig1DGDihydrofolate reductase1.5.1.30.475
2w3wVG9Dihydrofolate reductase/0.475
3ql3FOLDihydrofolate reductase1.5.1.30.475
4dpuAGSMevalonate diphosphate decarboxylase/0.475
4ia3BIVVitamin D3 receptor A/0.475
1d2sDHTSex hormone-binding globulin/0.474
1rjkVDZVitamin D3 receptor/0.474
3jsuKA5Bifunctional dihydrofolate reductase-thymidylate synthase/0.474
3qpnPFKcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.474
1bozPRDDihydrofolate reductase1.5.1.30.473
3gytDL4Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.473
3koo24DBifunctional epoxide hydrolase 23.3.2.100.473
3ntz3TZDihydrofolate reductase1.5.1.30.473
3w0gW07Vitamin D3 receptor/0.473
3w5rLOAVitamin D3 receptor/0.473
4hgt15GCasein kinase I isoform delta2.7.11.10.473
5bukFADFADH2-dependent halogenase/0.473
1synF89Thymidylate synthase/0.472
1uuoBRFDihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.472
2rehFADNitroalkane oxidase1.7.3.10.472
3gc9B45Mitogen-activated protein kinase 112.7.11.240.472
3meeT27Gag-Pol polyprotein2.7.7.490.472
3megT27Gag-Pol polyprotein2.7.7.490.472
3vtcTK3Vitamin D3 receptor/0.472
5jtbZMAAdenosine receptor A2a/0.472
1x2hLPALipoate-protein ligase A6.3.1.200.471
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.471
4ib4ERM5-hydroxytryptamine receptor 2B/0.471
5iua6DXAdenosine receptor A2a/0.471
1draMTXDihydrofolate reductase1.5.1.30.470
1m13HYFNuclear receptor subfamily 1 group I member 2/0.470
1tktH12Gag-Pol polyprotein2.7.7.490.470
2zlaVDBVitamin D3 receptor/0.470
3ghwGHWDihydrofolate reductase1.5.1.30.470
1c1bGCAGag-Pol polyprotein2.7.7.490.469
1f4fTP3Thymidylate synthase/0.469
1ie9VDXVitamin D3 receptor/0.469
1rc4DDFDihydrofolate reductase1.5.1.30.469
1revTB9Gag-Pol polyprotein2.7.7.490.469
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.469
2ev9NAPShikimate dehydrogenase (NADP(+))/0.469
3i0rRT3Gag-Pol polyprotein2.7.7.490.469
3vt65YIVitamin D3 receptor/0.469
4eiyZMAAdenosine receptor A2a/0.469
4fhi0S4Vitamin D3 receptor A/0.469
5iu4ZMAAdenosine receptor A2a/0.469
5k2bZMAAdenosine receptor A2a/0.469
3emlZMAAdenosine receptor A2a/0.469
1fpqSAMIsoliquiritigenin 2'-O-methyltransferase/0.468
1jtuLYBThymidylate synthase/0.468
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.468
3byzH11Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.468
3mdvCL6Cholesterol 24-hydroxylase/0.468
3w0iO11Vitamin D3 receptor/0.468
4bb6HD1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.468
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.468
4p68MTXDihydrofolate reductase/0.468
1dr3HBIDihydrofolate reductase1.5.1.30.467
1dtnAPGMandelate racemase/0.467
1o5rFR9Adenosine deaminase3.5.4.40.467
2hm9TRRDihydrofolate reductase1.5.1.30.467
3l08ZIGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.467
3r0tFU9Casein kinase II subunit alpha2.7.11.10.467
3vrwYS5Vitamin D3 receptor/0.467
3w0jT08Vitamin D3 receptor/0.467
4ezl0SEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.467
4itfTFYVitamin D3 receptor/0.467
5iu86DZAdenosine receptor A2a/0.467
1diuBDMDihydrofolate reductase1.5.1.30.466
1kceCB3Thymidylate synthase/0.466
1rkgVD1Vitamin D3 receptor/0.466
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.466
4ajfF03cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.466
4dieC5PCytidylate kinase/0.466
4iae1DXAlr2278 protein/0.466
4iteTEYVitamin D3 receptor/0.466
4kfj1R0Dihydrofolate reductase1.5.1.30.466
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.465
1hfpMOTDihydrofolate reductase1.5.1.30.465
1il0CAAHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.465
1jlaTNKGag-Pol polyprotein2.7.7.490.465
1tduCB3Thymidylate synthase/0.465
1y2c3DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.465
2op18PCEnoyl-ACP reductase/0.465
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.465
4o7uTHFThymidylate synthase/0.465
1blzACVIsopenicillin N synthase1.21.3.10.464
1lhvNOGSex hormone-binding globulin/0.464
2vssACOHydroxycinnamoyl-CoA hydratase-lyase4.1.2.410.464
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.464
3sgv2BJDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.464
4cd2FOLDihydrofolate reductase1.5.1.30.464
4h9506UDihydrofolate reductase1.5.1.30.464
4j6cSTRCytochrome P450 monooxygenase/0.464
4u9zCOAAlpha-tubulin N-acetyltransferase 1/0.464
1bzfTMQDihydrofolate reductase1.5.1.30.463
2fpcSCGStrictosidine synthase4.3.3.20.463
2g37FADProline dehydrogenase/0.463
2y30SM8Putative repressor SimReg2/0.463
3invNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.463
3och2MXDihydrofolate reductase1.5.1.30.463
3w0aDS5Vitamin D3 receptor/0.463
4bqg50QHeat shock protein HSP 90-alpha/0.463
4qysPLRTryptophan synthase beta chain 24.2.1.200.463
4wo5324Serine/threonine-protein kinase B-raf2.7.11.10.463
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.463
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.463
5uviZMAAdenosine receptor A2a/0.463
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.462
2zjwREFCasein kinase II subunit alpha2.7.11.10.462
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
1g6cIFPThiamine-phosphate synthase/0.461
1tl1H18Gag-Pol polyprotein2.7.7.490.461
1xoqROFcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.461
1y5rC0RCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.461
1zrzBI1Protein kinase C iota type2.7.11.130.461
2g78REACellular retinoic acid-binding protein 2/0.461
2h2qNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.461
3uweVJJAldo-keto reductase family 1 member C3/0.461
4elb34RDihydrofolate reductase/0.461
4xumIMNPeroxisome proliferator-activated receptor gamma/0.461
1f28UMPThymidylate synthase2.1.1.450.460
1ndzFR5Adenosine deaminase3.5.4.40.460
1x8b824Wee1-like protein kinase2.7.10.20.460
2gqg1N1Tyrosine-protein kinase ABL12.7.10.20.460
2rf2MRXGag-Pol polyprotein2.7.7.490.460
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
2ydoADNAdenosine receptor A2a/0.460
2zl9VDAVitamin D3 receptor/0.460
4kaoKAOFocal adhesion kinase 12.7.10.20.460
4qi9MTXDihydrofolate reductase/0.460
1tkzH16Gag-Pol polyprotein2.7.7.490.459
2b0m201Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.459
2zynBCDPeriplasmic binding protein/0.459
3bhlTHGThymidylate synthase/0.459
3ijdC2FMethylenetetrahydrofolate reductase/0.459
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.459
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.458
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.458
1lb9DNQGlutamate receptor 2/0.458
1lhwESMSex hormone-binding globulin/0.458
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.458
2obyNAPQuinone oxidoreductase PIG310.458
2qbs024Tyrosine-protein phosphatase non-receptor type 13.1.3.480.458
3fcoIIGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.458
3sx2NADUncharacterized protein/0.458
4feu537Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.458
4i7fNVEGag-Pol polyprotein2.7.7.490.458
4ky404JBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.458
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.457
1qxlFR8Adenosine deaminase3.5.4.40.457
1tbbROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.457
1tlcF89Thymidylate synthase/0.457
1zidZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.457
2b378PSEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.457
2bilBI1Serine/threonine-protein kinase pim-12.7.11.10.457
2z97CAMCamphor 5-monooxygenase1.14.15.10.457
3b8q900Vascular endothelial growth factor receptor 22.7.10.10.457
3d84NDPDihydrofolate reductase1.5.1.30.457
3ft8MOJHeat shock protein HSP 90-alpha/0.457
3gi2GHWDihydrofolate reductase1.5.1.30.457
3opdHIEHeat shock protein 83/0.457
3rusADPChaperonin/0.457
3zkuHCVIsopenicillin N synthase1.21.3.10.457
4yekTHMThymidine phosphorylase/0.457
1culFOKAdenylate cyclase type 2/0.456
1culFOKAdenylate cyclase type 5/0.456
1dg8NDPDihydrofolate reductase1.5.1.30.456
1kmvLIIDihydrofolate reductase1.5.1.30.456
2bakAQZMitogen-activated protein kinase 14/0.456
2f4jVX6Tyrosine-protein kinase ABL12.7.10.20.456
2hbhXE4Vitamin D3 receptor A/0.456
2vq5LDPS-norcoclaurine synthase/0.456
2ym2NAPPhenylacetone monooxygenase1.14.13.920.456
3cgcCOACoenzyme A disulfide reductase/0.456
3tm4SAMUncharacterized protein/0.456
3w0c6DSVitamin D3 receptor/0.456
3wrjCAMCamphor 5-monooxygenase1.14.15.10.456
4a9yAQZMitogen-activated protein kinase 14/0.456
4dk50KOPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
4j16NADNAD/NADP transhydrogenase alpha subunit 1/0.456
4jv618FRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.456
4rrwLURProstaglandin G/H synthase 21.14.99.10.456
4rrzLURProstaglandin G/H synthase 21.14.99.10.456
1cbqRE9Cellular retinoic acid-binding protein 2/0.455
1f5fDHTSex hormone-binding globulin/0.455
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.455
2ix5FADAcyl-coenzyme A oxidase 4, peroxisomal1.3.3.60.455
2pmdGNPTranslation initiation factor 2 subunit gamma/0.455
2vf0F89Thymidylate synthase/0.455
3bfa9ODOdorant binding protein ASP1/0.455
3g8eIS1Nicotinamide phosphoribosyltransferase2.4.2.120.455
3w0hW12Vitamin D3 receptor/0.455
3zecANPAdenosine monophosphate-protein transferase SoFic2.7.7.n10.455
4ckrDI1Epithelial discoidin domain-containing receptor 12.7.10.10.455
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.455
1f4gTP4Thymidylate synthase/0.454
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.454
1ot7CHCBile acid receptor/0.454
1q4xG24Thyroid hormone receptor beta/0.454
2fb8215Serine/threonine-protein kinase B-raf2.7.11.10.454
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.454
2zbaZBATrichothecene 3-O-acetyltransferase/0.454
3caqNDP3-oxo-5-beta-steroid 4-dehydrogenase/0.454
3dr1C5DVitamin D3 receptor A/0.454
3gb4D3MDdmC/0.454
3ntgD72Prostaglandin G/H synthase 21.14.99.10.454
3nxxNDPDihydrofolate reductase1.5.1.30.454
3vruYS3Vitamin D3 receptor/0.454
3vt45YIVitamin D3 receptor/0.454
3vtbTKAVitamin D3 receptor/0.454
4b8zNAPGDP-L-fucose synthase1.1.1.2710.454
4bgiI4IEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.454
4g2h0VQVitamin D3 receptor A/0.454
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.454
4kko1REGag-Pol polyprotein2.7.7.490.454
4qjqOTRLactoperoxidase/0.454
5ikqJMSProstaglandin G/H synthase 21.14.99.10.454
1fwmCB3Thymidylate synthase/0.453
1ppjANYCytochrome b/0.453
1rx8FOLDihydrofolate reductase1.5.1.30.453
2ovyPFJcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.453
3dds26BGlycogen phosphorylase, liver form2.4.1.10.453
3fwjCAMCamphor 5-monooxygenase1.14.15.10.453
3njoP2MAbscisic acid receptor PYR1/0.453
3oezSTIProto-oncogene tyrosine-protein kinase Src2.7.10.20.453
4f1sF1SPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.453
4jvf17XRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.453
5cyqT27Gag-Pol polyprotein2.7.7.490.453
1bq1CB3Thymidylate synthase/0.452
1hvyD16Thymidylate synthase2.1.1.450.452
1ju9NADAlcohol dehydrogenase E chain1.1.1.10.452
1sojIBMcGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.452
2a19ANPInterferon-induced, double-stranded RNA-activated protein kinase2.7.11.10.452
2xgs44PUncharacterized protein/0.452
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.452
3d574HYThyroid hormone receptor beta/0.452
3kjrNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.452
3q5iANPProtein kinase, putative/0.452
4g1d0VKVitamin D3 receptor A/0.452
4ia1BIVVitamin D3 receptor A/0.452
4l2yXXKPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/0.452
4mvh2F5cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.452
4q0a4OAVitamin D3 receptor A/0.452
5g53NECAdenosine receptor A2a/0.452
1drbMTXDihydrofolate reductase1.5.1.30.451
1kzjCB3Thymidylate synthase/0.451
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.451
1rt5UC2Gag-Pol polyprotein2.7.7.490.451
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.451
2ewaSB2Mitogen-activated protein kinase 14/0.451
2wqbQQ1Angiopoietin-1 receptor2.7.10.10.451
3pd2A3SThreonine--tRNA ligase6.1.1.30.451
3pd3A3TThreonine--tRNA ligase6.1.1.30.451
3up0D7SaceDAF-12/0.451
3zu2NAIEnoyl-[acyl-carrier-protein] reductase [NADH]/0.451
4rriA3TProbable threonine--tRNA ligase 26.1.1.30.451
4wdb2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.451
1dljUGAUDP-glucose 6-dehydrogenase/0.450
1fdwESTEstradiol 17-beta-dehydrogenase 11.1.1.620.450
1gwrESTEstrogen receptor/0.450
1ikvEFZGag-Pol polyprotein2.7.7.490.450
1rx1NAPDihydrofolate reductase1.5.1.30.450
1tl3H20Gag-Pol polyprotein2.7.7.490.450
1uyePU9Heat shock protein HSP 90-alpha/0.450
1wc0APCAdenylate cyclase/0.450
1zhzERGOxysterol-binding protein homolog 4/0.450
2jn3JN3Fatty acid-binding protein, liver/0.450
2prh238Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.450
2vkdUPGCytotoxin L/0.450
2ywvADPPhosphoribosylaminoimidazole-succinocarboxamide synthase/0.450
3b2eADPATPase GET3/0.450
3cgeCOACoenzyme A disulfide reductase/0.450
3d7kD7KBenzaldehyde lyase/0.450
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.450
3gkjHC3Niemann-Pick C1 protein/0.450
3ls8AJZPhosphatidylinositol 3-kinase catalytic subunit type 32.7.1.1370.450
3o0g3O0Cyclin-dependent-like kinase 52.7.11.10.450
3of2NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.450
3pqbVGPPutative oxidoreductase/0.450
3w5p4OAVitamin D3 receptor/0.450
3w5tLHPVitamin D3 receptor/0.450
4aosFADSteroid monooxygenase/0.450
4dquNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.450
4dtiNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.450
4ek1CAMCamphor 5-monooxygenase1.14.15.10.450
4g2gTDHMycocyclosin synthase1.14.21.90.450
4gevCB3Thymidylate synthase/0.450
4x5jFOLDihydrofolate reductase1.5.1.30.450
4xoqF42Coenzyme F420:L-glutamate ligase/0.450
5e8xSTUTGF-beta receptor type-12.7.11.300.450
1dkfBMSRetinoic acid receptor alpha/0.449
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.449
1sj0E4DEstrogen receptor/0.449
1tduDURThymidylate synthase/0.449
1umlFR4Adenosine deaminase3.5.4.40.449
1uu9BI33-phosphoinositide-dependent protein kinase 12.7.11.10.449
1y4lSVRBasic phospholipase A2 homolog 2/0.449
2etrY27Rho-associated protein kinase 12.7.11.10.449
2hw2RFPRifampin ADP-ribosyl transferase/0.449
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.449
2rhrEMOPutative ketoacyl reductase1.3.10.449
2wueKEK4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.449
3b9lAZZSerum albumin/0.449
3bejMUFBile acid receptor/0.449
3k47D09Dihydrofolate reductase1.5.1.30.449
3med65BGag-Pol polyprotein2.7.7.490.449
3nga3NGCasein kinase II subunit alpha2.7.11.10.449
3njoPYVAbscisic acid receptor PYR1/0.449
3p8iFMNPentaerythritol tetranitrate reductase/0.449
3s2a2NQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
3vrtYS2Vitamin D3 receptor/0.449
3vt9YI4Vitamin D3 receptor/0.449
3wsbRWZFarnesyltransferase, putative/0.449
3zuxTCHTransporter/0.449
4a33MYAGlycylpeptide N-tetradecanoyltransferase/0.449
4o1pANPRibonuclease L/0.449
4o71CPBBromodomain-containing protein 4/0.449
4q71FADBifunctional protein PutA/0.449
4riyADPEpidermal growth factor receptor2.7.10.10.449
3qakUKAAdenosine receptor A2a/0.449
1dhiMTXDihydrofolate reductase1.5.1.30.448
1pjkANPCasein kinase II subunit alpha2.7.11.10.448
1tvrTB9Gag-Pol polyprotein2.7.7.490.448
1wxyFRKAdenosine deaminase3.5.4.40.448
2a4nCOAAac(6')-Ii protein/0.448
2a4zBYMPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
2c59NADGDP-mannose 3,5-epimerase5.1.3.180.448
2e1mFADL-glutamate oxidase/0.448
2gjnFMNNitronate monooxygenase1.13.12.160.448
2oyuIMSProstaglandin G/H synthase 11.14.99.10.448
2q5oTPWIndole-3-pyruvate decarboxylase4.1.1.740.448
2z7gEH9Adenosine deaminase3.5.4.40.448
3mqe416Prostaglandin G/H synthase 21.14.99.10.448
3oquA8SAbscisic acid receptor PYL9/0.448
3qlhT27Gag-Pol polyprotein2.7.7.490.448
4cdmFO1Deoxyribodipyrimidine photolyase/0.448
4ge70K5Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.448
4j6dTESCytochrome P450 monooxygenase/0.448
4kfn1QRNicotinamide phosphoribosyltransferase2.4.2.120.448
4kl9NDPDihydrofolate reductase1.5.1.30.448
4l17DNQGlutamate receptor 2/0.448
4l23X6KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/0.448
4rujVDXVitamin D3 receptor A/0.448
5gcnCOAHAT A1/0.448
5iubCLRAdenosine receptor A2a/0.448
1enzNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.447
1hquHBYGag-Pol polyprotein2.7.7.490.447
1ikwEFZGag-Pol polyprotein2.7.7.490.447
1n83CLRNuclear receptor ROR-alpha/0.447
1pl8NADSorbitol dehydrogenase1.1.1.140.447
1rt4UC1Gag-Pol polyprotein2.7.7.490.447
1uhoVDNcGMP-specific 3',5'-cyclic phosphodiesterase/0.447
2ban357Gag-Pol polyprotein2.7.7.490.447
2ittAEEEpidermal growth factor receptor2.7.10.10.447
2kceD16Thymidylate synthase/0.447
2po7CHDFerrochelatase, mitochondrial4.99.1.10.447
2vcmM11Isopenicillin N synthase1.21.3.10.447
2yeiXQIHeat shock protein HSP 90-alpha/0.447
2yjxYJXHeat shock protein HSP 90-alpha/0.447
2ynfWHUGag-Pol polyprotein2.7.7.490.447
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
3ce31FNHepatocyte growth factor receptor2.7.10.10.447
3cmfPDN3-oxo-5-beta-steroid 4-dehydrogenase/0.447
3dhcCYKN-acyl homoserine lactonase AiiA3.1.1.810.447
3h3t16HCollagen type IV alpha-3-binding protein/0.447
3owj1ELCasein kinase II subunit alpha2.7.11.10.447
3p8jFMNPentaerythritol tetranitrate reductase/0.447
3qf9NM8Serine/threonine-protein kinase pim-12.7.11.10.447
3sn7540cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.447
4dymIYZActivin receptor type-12.7.11.300.447
4gutFADLysine-specific histone demethylase 1B10.447
4i2pG73Gag-Pol polyprotein2.7.7.490.447
4ifvT27Gag-Pol polyprotein2.7.7.490.447
4j4vSVRNucleocapsid protein/0.447
4jlm1NNDeoxycytidine kinase2.7.1.740.447
1nq14HYThyroid hormone receptor beta/0.446
1q9mROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.446
1xorZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.446
2acwUPGGlycosyltransferase/0.446
2fszOHTEstrogen receptor beta/0.446
2fzjDH3Dihydrofolate reductase1.5.1.30.446
2itnANPEpidermal growth factor receptor2.7.10.10.446
2jfgUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.446
2pg0FADAcyl-CoA dehydrogenase/0.446
2qak1UNGag-Pol polyprotein3.4.23.160.446
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.446
3ansS38Bifunctional epoxide hydrolase 23.3.2.100.446
3gcq1BUMitogen-activated protein kinase 14/0.446
3vf60H6Glucokinase2.7.1.20.446
3zw3ZW3Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
4bb3KKAIsopenicillin N synthase1.21.3.10.446
4ckcSAHmRNA-capping enzyme catalytic subunit2.1.1.560.446
4f7iNAD3-isopropylmalate dehydrogenase1.1.1.850.446
4h0xNADIota toxin component Ia/0.446
4heu15JcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.446
4j26ESTEstrogen receptor beta/0.446
4kbn25UDihydrofolate reductase1.5.1.30.446
5kgpACOPredicted acetyltransferase/0.446
1g4sTPSThiamine-phosphate synthase/0.445
1v7aFRCAdenosine deaminase3.5.4.40.445
2c96ATPPsp operon transcriptional activator/0.445
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.445
2w6oOA3Biotin carboxylase6.3.4.140.445
2y6fM9FIsopenicillin N synthase1.21.3.10.445
3b8r887Vascular endothelial growth factor receptor 22.7.10.10.445
3gtsD3MDdmC/0.445
3ibqATPPyridoxal kinase/0.445
3jpv1DRSerine/threonine-protein kinase pim-12.7.11.10.445
3ln1CELProstaglandin G/H synthase 21.14.99.10.445
3m8qDJZGag-Pol polyprotein2.7.7.490.445
3ns2PYVAbscisic acid receptor PYL2/0.445
3o56ZG1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.445
3s7a684Dihydrofolate reductase1.5.1.30.445
3stw2TDMethylketone synthase I/0.445
3w0tHPULactoylglutathione lyase4.4.1.50.445
4jlk1NODeoxycytidine kinase2.7.1.740.445
4m69ANPReceptor-interacting serine/threonine-protein kinase 32.7.11.10.445
4nb6444Nuclear receptor ROR-gamma/0.445
6cp4CAMCamphor 5-monooxygenase1.14.15.10.445
1a72PADAlcohol dehydrogenase E chain1.1.1.10.444
1cbfSAHCobalt-precorrin-4 C(11)-methyltransferase2.1.1.2710.444
1lcoPPYCytochrome b2, mitochondrial1.1.2.30.444
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.444
1qvnFRIInterleukin-2/0.444
1uwhBAXSerine/threonine-protein kinase B-raf2.7.11.10.444
1yqj6NPMitogen-activated protein kinase 14/0.444
1zeoC01Peroxisome proliferator-activated receptor gamma/0.444
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.444
2bxmIMNSerum albumin/0.444
2ejvNADL-threonine 3-dehydrogenase/0.444
2wotZZGTGF-beta receptor type-12.7.11.300.444
2yee2ECHeat shock protein HSP 90-alpha/0.444
3a1l2CCCytochrome P450/0.444
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.444
3n0hTOPDihydrofolate reductase1.5.1.30.444
3ua506XCytochrome P450 2B61.14.130.444
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.444
3vjhJ35Peroxisome proliferator-activated receptor gamma/0.444
4bfxZVXPantothenate kinase2.7.1.330.444
4eevL1XHepatocyte growth factor receptor2.7.10.10.444
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.444
4kbk1QGCasein kinase I isoform delta2.7.11.10.444
4lcg1WMUDP-3-O-acyl-N-acetylglucosamine deacetylase/0.444
4qa2SHHHistone deacetylase 83.5.1.980.444
5c8yACPTubulin tyrosine ligase/0.444
5cc9DDFDihydrofolate reductase1.5.1.30.444
5eccNAPDehydrofolate reductase type I/0.444
5k2dZMAAdenosine receptor A2a/0.444
1bh5GTXLactoylglutathione lyase4.4.1.50.443
1dr5NAPDihydrofolate reductase1.5.1.30.443
1dtpAPUDiphtheria toxin/0.443
1g28FMNPHY3/0.443
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.443
1ndyFR3Adenosine deaminase3.5.4.40.443
1q4wDQUQueuine tRNA-ribosyltransferase2.4.2.290.443
1sezOMNProtoporphyrinogen oxidase, mitochondrial1.3.3.40.443
1u2gAPRNAD(P) transhydrogenase subunit alpha part 11.6.1.20.443
1w83L11Mitogen-activated protein kinase 14/0.443
2atiIHUGlycogen phosphorylase, liver form2.4.1.10.443
2zaxCAMCamphor 5-monooxygenase1.14.15.10.443
3bloQEIQueuine tRNA-ribosyltransferase2.4.2.290.443
3czr3CZCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.443
3el8PD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.443
3eyaTDPPyruvate dehydrogenase [ubiquinone]1.2.5.10.443
3g4gD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
3g5qFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.443
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
3qpoPFRcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.443
3vbq0F5Serine/threonine-protein kinase pim-12.7.11.10.443
3vt7VDXVitamin D3 receptor/0.443
3wrmCAMCamphor 5-monooxygenase1.14.15.10.443
4bbxLKFcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.443
4j7xSASSepiapterin reductase1.1.1.1530.443
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.443
4obuPLPPyridoxal-dependent decarboxylase domain protein/0.443
4rr7A3SProbable threonine--tRNA ligase 26.1.1.30.443
4wh3ATPN-acetylhexosamine 1-kinase2.7.1.1620.443
4xcvNDPProbable hydroxyacid dehydrogenase protein/0.443
4xx0COASuccinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial6.2.1.40.443
5bp9SAHPutative methyltransferase protein/0.443
5c80URIUridine phosphorylase/0.443
5im3DTPRibonucleoside-diphosphate reductase/0.443
1iyzNDPProbable quinone oxidoreductase/0.442
1jlcFTCGag-Pol polyprotein2.7.7.490.442
1lwlDSOCamphor 5-monooxygenase1.14.15.10.442
1qknRALEstrogen receptor beta/0.442
1x8lOXRRetinol dehydratase/0.442
1y2d4DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.442
1y2e5DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.442
2eq7NADDihydrolipoyl dehydrogenase/0.442
2gblATPCircadian clock protein kinase KaiC2.7.11.10.442
2i40BLZCyclin-dependent kinase 22.7.11.220.442
2jc6QPPCalcium/calmodulin-dependent protein kinase type 1D2.7.11.170.442
2pbwDOQGlutamate receptor ionotropic, kainate 1/0.442
2puiADPMethylthioribose kinase2.7.1.1000.442
2vbpVB1Isopenicillin N synthase1.21.3.10.442
2wi72KLHeat shock protein HSP 90-alpha/0.442
2wufKEM4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.442
2y37A54Nitric oxide synthase, inducible1.14.13.390.442
3d0bSNXHeat shock protein HSP 90-alpha/0.442
3hv6R39Mitogen-activated protein kinase 14/0.442
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
3nd1SAHPrecorrin-6A synthase (Deacetylating)/0.442
3pe6ZYHMonoglyceride lipase/0.442
3qlg1N1Proto-oncogene tyrosine-protein kinase Src2.7.10.20.442
3t2vKKJPeptidoglycan recognition protein 1/0.442
3v3m0ENReplicase polyprotein 1a3.4.19.120.442
3w0oADPHygromycin-B 4-O-kinase2.7.1.1630.442
4ajwVWNPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform2.7.1.1530.442
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
4bwaN0BPyrrolysine--tRNA ligase/0.442
4gk3L87Ephrin type-A receptor 32.7.10.10.442
4nky3QZSteroid 17-alpha-hydroxylase/17,20 lyase/0.442
5h8tRTLRetinol-binding protein 1/0.442
1ai9NDPDihydrofolate reductase1.5.1.30.441
1ewyFADFerredoxin--NADP reductase1.18.1.20.441
1fgiSU1Fibroblast growth factor receptor 1/0.441
1fmlRTLRetinol dehydratase/0.441
1o6rR19Squalene--hopene cyclase4.2.1.1290.441
1oriSAHProtein arginine N-methyltransferase 1/0.441
1s2cFLFAldo-keto reductase family 1 member C3/0.441
1uymPU3Heat shock protein HSP 90-beta/0.441
1w4zNAPPutative ketoacyl reductase1.3.10.441
1y7uCOAAcyl-CoA hydrolase/0.441
1yrcCAMCamphor 5-monooxygenase1.14.15.10.441
2fwyH64Heat shock protein HSP 90-alpha/0.441
2iebZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
2ze2T27Gag-Pol polyprotein2.7.7.490.441
3be2RAJVascular endothelial growth factor receptor 22.7.10.10.441
3bqr4RBDeath-associated protein kinase 3/0.441
3cbsR12Cellular retinoic acid-binding protein 2/0.441
3cppCAMCamphor 5-monooxygenase1.14.15.10.441
3dd125DGlycogen phosphorylase, liver form2.4.1.10.441
3gobHXXDdmC/0.441
3hz5Z64Heat shock protein HSP 90-alpha/0.441
3n8wFLPProstaglandin G/H synthase 11.14.99.10.441
3nxvD2FDihydrofolate reductase1.5.1.30.441
3oct1N1Tyrosine-protein kinase BTK2.7.10.20.441
3pxkPXKFocal adhesion kinase 12.7.10.20.441
3qm4PN0Cytochrome P450 2D6/0.441
3sl6JN8cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.441
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.441
3w9rA8SAbscisic acid receptor PYL9/0.441
3wgwT2BProliferating cell nuclear antigen/0.441
3zewSTUEphrin type-B receptor 42.7.10.10.441
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.441
4c02TAKActivin receptor type-12.7.11.300.441
4c66H4CBromodomain-containing protein 4/0.441
4eudCOASuccinyl-CoA:acetate CoA-transferase/0.441
4fuyEK2Mitogen-activated protein kinase 12.7.11.240.441
4gb90WRPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
4iah1DXAlr2278 protein/0.441
4j6bPLOCytochrome P450 monooxygenase/0.441
4jbtASDCytochrome P450 monooxygenase/0.441
4jia1K3Tyrosine-protein kinase JAK2/0.441
4x5iFOLDihydrofolate reductase1.5.1.30.441
4xivADPChemotaxis protein CheA2.7.13.30.441
5dp2NAPCurF/0.441
1an5CB3Thymidylate synthase/0.440
1bucFADAcyl-CoA dehydrogenase, short-chain specific1.3.8.10.440
1dhjMTXDihydrofolate reductase1.5.1.30.440
1ejiTHFSerine hydroxymethyltransferase, cytosolic/0.440
1hk5T44Serum albumin/0.440
1pydTDPPyruvate decarboxylase isozyme 1/0.440
1rekB8LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
1rr6IMHPurine nucleoside phosphorylase2.4.2.10.440
1tf7ATPCircadian clock protein kinase KaiC2.7.11.10.440
1uyhPU0Heat shock protein HSP 90-alpha/0.440
2izsBRQCasein kinase I isoform gamma-32.7.11.10.440
2o0uC0MMitogen-activated protein kinase 102.7.11.240.440
2uw7GVPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
3c3eFO12-phospho-L-lactate transferase/0.440
3dbvNADGlyceraldehyde-3-phosphate dehydrogenase/0.440
3dxjNE6DNA-directed RNA polymerase subunit beta/0.440
3dxjNE6DNA-directed RNA polymerase subunit beta'/0.440
3fsuC2F5,10-methylenetetrahydrofolate reductase1.5.1.200.440
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.440
3l3rOAGDihydrofolate reductase1.5.1.30.440
3pe2E1BCasein kinase II subunit alpha2.7.11.10.440
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.440
3qfvNM7Serine/threonine-protein kinase MRCK beta2.7.11.10.440
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.440
3tvxPNXcAMP-specific 3',5'-cyclic phosphodiesterase 4A3.1.4.530.440
3ue4DB8Tyrosine-protein kinase ABL12.7.10.20.440
3vrvYSDVitamin D3 receptor/0.440
3zvvXAZPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
4alhA9PBromodomain-containing protein 2/0.440
4bqrIBHEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
4eerFMNPhototropin-22.7.11.10.440
4fdnFADDecaprenylphosphoryl-beta-D-ribose oxidase/0.440
4fweFADLysine-specific histone demethylase 1B10.440
4ia7BIVVitamin D3 receptor A/0.440
4rraA3TProbable threonine--tRNA ligase 26.1.1.30.440
4ucnMYAGlycylpeptide N-tetradecanoyltransferase/0.440