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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2vr0HQOCytochrome c-type protein

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
2vr0HQOCytochrome c-type protein/1.000
4a4o664Serine/threonine-protein kinase PLK12.7.11.210.511
3zoiM2WIsopenicillin N synthase1.21.3.10.506
1hb1OCVIsopenicillin N synthase1.21.3.10.505
2jdtI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.503
5fe112QHistone acetyltransferase KAT2B2.3.1.480.503
3b9lAZZSerum albumin/0.502
2a0yDIHPurine nucleoside phosphorylase2.4.2.10.501
1obnASVIsopenicillin N synthase1.21.3.10.500
2wo7ASVIsopenicillin N synthase1.21.3.10.500
2z2w770Wee1-like protein kinase2.7.10.20.499
2a4xBLMMitomycin-binding protein/0.498
3wt0ATPCell division protein FtsA/0.498
5icfSAH(S)-norcoclaurine 6-O-methyltransferase/0.497
3gytDL4Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.496
2vbdV10Isopenicillin N synthase1.21.3.10.495
2in6839Wee1-like protein kinase2.7.10.20.492
2uw5GVNcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.492
3friSAH16S rRNA methylase/0.492
3mteSAM16S rRNA (adenine(1408)-N(1))-methyltransferase2.1.1.1800.490
3juqAJDPhenazine biosynthesis protein A/B/0.489
4isuIKMGlutamate receptor 2/0.489
1bk0ACVIsopenicillin N synthase1.21.3.10.488
4ugaH4BNitric oxide synthase oxygenase1.14.13.1650.488
1rr6IMHPurine nucleoside phosphorylase2.4.2.10.487
3h3qH13Collagen type IV alpha-3-binding protein/0.486
1sg9SAMRelease factor glutamine methyltransferase2.1.1.2970.485
4ug7H4BNitric oxide synthase oxygenase1.14.13.1650.485
3sm0AEKQueuine tRNA-ribosyltransferase2.4.2.290.484
4rvnCOAPhenylacetate-coenzyme A ligase/0.484
1nv8SAMRelease factor glutamine methyltransferase2.1.1.2970.482
1nw3SAMHistone-lysine N-methyltransferase, H3 lysine-79 specific2.1.1.430.481
2vbpVB1Isopenicillin N synthase1.21.3.10.481
2xk85R1Serine/threonine-protein kinase Nek22.7.11.10.481
3fp0FP015-O-acetyltransferase/0.481
3reoSAH(Iso)eugenol O-methyltransferase2.1.1.1460.481
4uqsINENitric oxide synthase oxygenase1.14.13.1650.480
4xz3COAAcyl-CoA synthetase (NDP forming)/0.480
1f28F89Thymidylate synthase2.1.1.450.479
1j8uH4BPhenylalanine-4-hydroxylase1.14.16.10.479
1t13INI6,7-dimethyl-8-ribityllumazine synthase 2/0.479
3vyeVYERenin3.4.23.150.479
5kbwRBFRiboflavin transporter RibU/0.479
4m4821BSodium-dependent dopamine transporter/0.478
2a9z26AAdenosine kinase2.7.1.200.477
2jb4A14Isopenicillin N synthase1.21.3.10.477
3wqtANPCell division protein FtsA/0.477
4pb25UDNucleoside permease/0.477
4zo3C6LAcylhomoserine lactonase/0.477
1gpeFADGlucose oxidase1.1.3.40.476
2iviACWIsopenicillin N synthase1.21.3.10.476
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.476
3lpfZ77Beta-glucuronidase3.2.1.310.476
2j2pSC2Ficolin-2/0.475
2w5bAGSSerine/threonine-protein kinase Nek22.7.11.10.475
2xkdT3MSerine/threonine-protein kinase Nek22.7.11.10.475
4g95OAGDihydrofolate reductase1.5.1.30.475
1bim0QBRenin3.4.23.150.474
1qw5H4BNitric oxide synthase, inducible1.14.13.390.474
2p1v5TNRetinoic acid receptor RXR-alpha/0.474
2xvw9NRSerum albumin/0.474
4twnB96Ephrin type-A receptor 32.7.10.10.474
1e2nRCAThymidine kinase/0.473
2aclREARetinoic acid receptor RXR-alpha/0.473
2d4h5GPGuanylate-binding protein 1/0.473
2vcmM11Isopenicillin N synthase1.21.3.10.473
3junAJDPhenazine biosynthesis protein A/B/0.473
1n77ATPGlutamate--tRNA ligase6.1.1.170.472
1tsdF89Thymidylate synthase/0.472
2xkeWI2Serine/threonine-protein kinase Nek22.7.11.10.472
2y60M8FIsopenicillin N synthase1.21.3.10.472
3bi6396Wee1-like protein kinase2.7.10.20.472
1hb3SCVIsopenicillin N synthase1.21.3.10.471
2rqfJH3Hemolymph juvenile hormone binding protein/0.471
3b5iSAHIndole-3-acetate O-methyltransferase 1/0.471
3h3r14HCollagen type IV alpha-3-binding protein/0.471
3junAKDPhenazine biosynthesis protein A/B/0.471
1afeALZProthrombin3.4.21.50.470
1dliUDXUDP-glucose 6-dehydrogenase/0.470
1i2lDCSAminodeoxychorismate lyase4.1.3.380.470
1mjtNADNitric oxide synthase oxygenase/0.470
1wklATPNucleoside diphosphate kinase/0.470
3bbfGDPNucleoside diphosphate kinase B2.7.4.60.470
3qge26FGenome polyprotein2.7.7.480.470
4yqfGDPSeptin-9/0.470
1d2sDHTSex hormone-binding globulin/0.469
1rt9IMHPurine nucleoside phosphorylase2.4.2.10.469
2bxqIMNSerum albumin/0.469
2cmoM1LGlutamate receptor 2/0.469
4gg90WWQueuine tRNA-ribosyltransferase2.4.2.290.469
4i13FOLDihydrofolate reductase1.5.1.30.469
5f2kSAHUncharacterized protein/0.469
1krv147Galactoside O-acetyltransferase2.3.1.180.468
1x8lOXRRetinol dehydratase/0.468
2uw6GVOcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.468
3el7PD3Proto-oncogene tyrosine-protein kinase Src2.7.10.20.468
4ug91EWNitric oxide synthase oxygenase1.14.13.1650.468
1geuFADGlutathione reductase1.8.1.70.467
1qjfACSIsopenicillin N synthase1.21.3.10.467
1w06W05Isopenicillin N synthase1.21.3.10.467
2vo0M03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.467
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.467
1b2lNDCAlcohol dehydrogenase1.1.1.10.466
1lvu9PPPurine nucleoside phosphorylase2.4.2.10.466
1uxuNAPNAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase/0.466
3c35KAIGlutamate receptor ionotropic, kainate 1/0.466
3h3t16HCollagen type IV alpha-3-binding protein/0.466
3own3OWRenin3.4.23.150.466
4b6l9ZPSerine/threonine-protein kinase PLK32.7.11.210.466
4c6zTLE3-oxoacyl-ACP synthase/0.466
1c3x8IGPurine nucleoside phosphorylase2.4.2.10.465
1g9rUPFLgtC/0.465
1mvsDTMDihydrofolate reductase1.5.1.30.465
2x9vTMQPteridine reductase/0.465
3sqxANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.465
3wquATPCell division protein FtsA/0.465
2cjfRP43-dehydroquinate dehydratase4.2.1.100.464
2clfF6FTryptophan synthase alpha chain/0.464
2ewaSB2Mitogen-activated protein kinase 14/0.464
3qi4IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.464
3sqwANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.464
4gcmNAPThioredoxin reductase1.8.1.90.464
4nbb9CATerminal oxygenase component of carbazole/0.464
1dljUGAUDP-glucose 6-dehydrogenase/0.463
1ludTRRDihydrofolate reductase1.5.1.30.463
2gzl2AA2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase4.6.1.120.463
3fwjCAMCamphor 5-monooxygenase1.14.15.10.463
3jt7H4BNitric oxide synthase, brain1.14.13.390.463
3l7gM44Xaa-Pro dipeptidase3.4.13.90.463
3pdnSFGHistone-lysine N-methyltransferase SMYD32.1.1.430.463
4lwaQ13Nitric oxide synthase oxygenase1.14.13.1650.463
4py6R78Bromodomain protein, putative/0.463
1dr4HBIDihydrofolate reductase1.5.1.30.462
1klkPMDDihydrofolate reductase1.5.1.30.462
1nqvLMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.462
1oc1ASVIsopenicillin N synthase1.21.3.10.462
1qpbTPPPyruvate decarboxylase isozyme 1/0.462
2c1aI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.462
2o98FSC14-3-3-like protein C/0.462
3hv3R49Mitogen-activated protein kinase 14/0.462
4ea2RWZDehydrosqualene synthase/0.462
4uy6SAHHistidine N-alpha-methyltransferase/0.462
2xk4OL2Serine/threonine-protein kinase Nek22.7.11.10.461
3juoAJDPhenazine biosynthesis protein A/B/0.461
3zkyWT4Isopenicillin N synthase1.21.3.10.461
4bdrKAIGlutamate receptor ionotropic, kainate 2/0.461
4ek1CAMCamphor 5-monooxygenase1.14.15.10.461
4js9H4BNitric oxide synthase, inducible1.14.13.390.461
3uzaT4GAdenosine receptor A2a/0.461
2ea2F77Methionine aminopeptidase 2/0.460
2vroNDP3,4-dehydroadipyl-CoA semialdehyde dehydrogenase/0.460
3d78NBBPheromone-binding protein ASP1/0.460
3rhlNAPCytosolic 10-formyltetrahydrofolate dehydrogenase1.5.1.60.460
5k2cZMAAdenosine receptor A2a/0.460
3uzcT4EAdenosine receptor A2a/0.460
1dpmEBPParathion hydrolase3.1.8.10.459
1fmjRTLRetinol dehydratase/0.459
1fx9MJIPhospholipase A2, major isoenzyme3.1.1.40.459
1jdzFMBPurine nucleoside phosphorylase/0.459
1kuvCA5Serotonin N-acetyltransferase/0.459
1wnbNAIGamma-aminobutyraldehyde dehydrogenase1.2.1.190.459
2uuk897Prothrombin3.4.21.50.459
3gyuDL7Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.459
3p9tTCLRepressor/0.459
3pd2A3SThreonine--tRNA ligase6.1.1.30.459
3x025GPPhosphatidylinositol 5-phosphate 4-kinase type-2 beta2.7.1.1490.459
4ms1381Gamma-aminobutyric acid type B receptor subunit 1/0.459
3pblETQD(3) dopamine receptor/0.459
1dr3TAPDihydrofolate reductase1.5.1.30.458
1kuyCOTSerotonin N-acetyltransferase/0.458
1lb9DNQGlutamate receptor 2/0.458
1owpFADDeoxyribodipyrimidine photo-lyase4.1.99.30.458
3g5mFADRibosyldihydronicotinamide dehydrogenase [quinone]/0.458
3vywSAMUncharacterized protein/0.458
4biwANPSensor histidine kinase CpxA/0.458
4y3zF41Endothiapepsin3.4.23.220.458
1m8hH4BNitric oxide synthase, inducible1.14.13.390.457
2pbwDOQGlutamate receptor ionotropic, kainate 1/0.457
2w0hFADTrypanothione reductase/0.457
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.457
3itzP66Mitogen-activated protein kinase 14/0.457
3juqAKDPhenazine biosynthesis protein A/B/0.457
4fr10V2Queuine tRNA-ribosyltransferase2.4.2.290.457
1gnwGTXGlutathione S-transferase F22.5.1.180.456
2bsxNOSPurine nucleoside phosphorylase/0.456
2c94TSF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.456
2ohjFMNType A flavoprotein FprA10.456
2xnpWCXSerine/threonine-protein kinase Nek22.7.11.10.456
3fktSIIBeta-secretase 13.4.23.460.456
3uxvGUNNADPH-dependent 7-cyano-7-deazaguanine reductase/0.456
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.456
4f1mACPProbable serine/threonine-protein kinase roco42.7.11.10.456
4x7zZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.456
5ex0SAHHistone-lysine N-methyltransferase SMYD32.1.1.430.456
1ozqPRFQueuine tRNA-ribosyltransferase2.4.2.290.455
1x2hLPALipoate-protein ligase A6.3.1.200.455
2a2xNA9Prothrombin3.4.21.50.455
2f7z6EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.455
2qblCAMCamphor 5-monooxygenase1.14.15.10.455
3ipkPMSSurface protein adhesin/0.455
4ug5H4BNitric oxide synthase oxygenase1.14.13.1650.455
1giqNAIIota toxin component Ia/0.454
1ia9ANPTransient receptor potential cation channel subfamily M member 72.7.11.10.454
1jdvADNPurine nucleoside phosphorylase/0.454
1qiqACCIsopenicillin N synthase1.21.3.10.454
2a1mCAMCamphor 5-monooxygenase1.14.15.10.454
2bu9HFVIsopenicillin N synthase1.21.3.10.454
2owb626Serine/threonine-protein kinase PLK12.7.11.210.454
2y882ERPhosphoribosyl isomerase A5.3.1.160.454
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.454
2zrzFNRIsopentenyl-diphosphate delta-isomerase/0.454
3cqeP91Wee1-like protein kinase2.7.10.20.454
3jt5H4BNitric oxide synthase, brain1.14.13.390.454
3qvrFADGlucose oxidase1.1.3.40.454
3vo2FADFerredoxin--NADP reductase/0.454
4c36ZO9cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.454
4fgcPQ0NADPH-dependent 7-cyano-7-deazaguanine reductase1.7.1.130.454
4isg1FYGlucokinase2.7.1.20.454
4oe4NADDelta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial1.2.1.880.454
4uyg73BBromodomain-containing protein 2/0.454
5jtbZMAAdenosine receptor A2a/0.454
1tllFMNNitric oxide synthase, brain1.14.13.390.453
2poqISDTrans-1,2-dihydrobenzene-1,2-diol dehydrogenase1.3.1.200.453
2wqoVGKSerine/threonine-protein kinase Nek22.7.11.10.453
2yac937Serine/threonine-protein kinase PLK12.7.11.210.453
3p9kSAHCaffeic acid O-methyltransferase/0.453
3rthRTHBeta-secretase 13.4.23.460.453
4dcmSAMRibosomal RNA large subunit methyltransferase G2.1.1.1740.453
4eevL1XHepatocyte growth factor receptor2.7.10.10.453
4euxH4BNitric oxide synthase, brain1.14.13.390.453
4gh10WXQueuine tRNA-ribosyltransferase2.4.2.290.453
4k9yK9YFocal adhesion kinase 12.7.10.20.453
4rrhA3SProbable threonine--tRNA ligase 26.1.1.30.453
4ug71EVNitric oxide synthase oxygenase1.14.13.1650.453
1mvcBM6Retinoic acid receptor RXR-alpha/0.452
1o9bNAIQuinate/shikimate dehydrogenase/0.452
1rszDIHPurine nucleoside phosphorylase2.4.2.10.452
1uwhBAXSerine/threonine-protein kinase B-raf2.7.11.10.452
1zisINI6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.452
2c29NAPDihydroflavonol 4-reductase/0.452
3b9oFMNAlkane monoxygenase/0.452
3c3xNAPEugenol synthase 11.1.1.3180.452
3irm1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.452
3jypNADQuinate/shikimate dehydrogenase (NAD(+))/0.452
3lcuSAH16S rRNA (guanine(1405)-N(7))-methyltransferase2.1.1.1790.452
3qvwNADMyo-inositol-1-phosphate synthase (Ino1)/0.452
3vilSA0Beta-glucosidase/0.452
4a802ANMajor pollen allergen Bet v 1-A/0.452
4ek9EP4Histone-lysine N-methyltransferase, H3 lysine-79 specific2.1.1.430.452
4iueAJ4Tankyrase-22.4.2.300.452
4m8e29VRetinoic acid receptor RXR-alpha/0.452
1ftlDNQGlutamate receptor 2/0.451
1xm1GAHProthrombin3.4.21.50.451
2a5kAZPReplicase polyprotein 1ab3.4.220.451
2gu8796cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.451
2nm2NEUDihydroneopterin aldolase/0.451
2xf3J01Uncharacterized protein/0.451
3p2kSAM16S rRNA (adenine(1408)-N(1))-methyltransferase2.1.1.1800.451
3q99H4BNitric oxide synthase, brain1.14.13.390.451
3tg4SAMN-lysine methyltransferase SMYD2/0.451
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
4ivqI43Thymidine kinase/0.451
4jseH4BNitric oxide synthase, brain1.14.13.390.451
4k6i9RARetinoic acid receptor RXR-alpha/0.451
4ug5XFKNitric oxide synthase oxygenase1.14.13.1650.451
1blzACVIsopenicillin N synthase1.21.3.10.450
1q0zAKAAclacinomycin methylesterase RdmC3.1.1.950.450
1t87CAMCamphor 5-monooxygenase1.14.15.10.450
1txtCAAHMG-CoA synthase/0.450
1uzwCDHIsopenicillin N synthase1.21.3.10.450
2gvdFKPAdenylate cyclase type 2/0.450
2gvdFKPAdenylate cyclase type 5/0.450
3deiRXBCaspase-33.4.22.560.450
3jq6DX1Pteridine reductase, putative/0.450
3jt9H4BNitric oxide synthase, brain1.14.13.390.450
4ctjSAMGenome polyprotein/0.450
4ec3RENReticuline oxidase1.21.3.30.450
4req5ADMethylmalonyl-CoA mutase large subunit5.4.99.20.450
4u9zCOAAlpha-tubulin N-acetyltransferase 1/0.450
5erm210Fusicoccadiene synthase4.2.3.430.450
1cdeDZFPhosphoribosylglycinamide formyltransferase/0.449
1uaeUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.449
1w19T1P6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.449
1yplRA8Prothrombin3.4.21.50.449
2a9y26AAdenosine kinase2.7.1.200.449
2b82ADNClass B acid phosphatase3.1.3.20.449
2bhwLUXChlorophyll a-b binding protein AB80, chloroplastic/0.449
2f99AKVAklanonic acid methyl ester cyclase AcmA5.5.1.230.449
2h2qNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.449
2hkoFADLysine-specific histone demethylase 1A10.449
2j9lATPH(+)/Cl(-) exchange transporter 5/0.449
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.449
2pdfZSTAldose reductase1.1.1.210.449
2wi72KLHeat shock protein HSP 90-alpha/0.449
3h2cB58Dihydropteroate synthase/0.449
4ddrMMVDihydrofolate reductase1.5.1.30.449
4l4aCAMCamphor 5-monooxygenase1.14.15.10.449
5fa8SAMRibosomal protein L11 methyltransferase, putative/0.449
1lnyIMOAdenylosuccinate synthetase isozyme 1/0.448
2aqbTL63-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.448
2bxmIMNSerum albumin/0.448
2gtbAZPOrf1ab polyprotein/0.448
2hxzH7JCathepsin S3.4.22.270.448
2ipjFFAAldo-keto reductase family 1 member C2/0.448
2iqgF2IBeta-secretase 13.4.23.460.448
2xvv9DNSerum albumin/0.448
3adaNADSubunit alpha of sarocosine oxidase/0.448
3m3z3F5Heat shock cognate 71 kDa protein/0.448
3p84FMNPentaerythritol tetranitrate reductase/0.448
3rzpPRFNADPH-dependent 7-cyano-7-deazaguanine reductase/0.448
3up0D7SaceDAF-12/0.448
4a86H35Major pollen allergen Bet v 1-A/0.448
4c43FADFerredoxin--NADP reductase1.18.1.20.448
4nbn2J7Caspase-63.4.22.590.448
4psgNOHThymidylate synthase/0.448
4rriA3TProbable threonine--tRNA ligase 26.1.1.30.448
5hq8SAHHistone-lysine N-methyltransferase SMYD32.1.1.430.448
5k2dZMAAdenosine receptor A2a/0.448
3qakUKAAdenosine receptor A2a/0.448
1owoFADDeoxyribodipyrimidine photo-lyase4.1.99.30.447
1pxgPRFQueuine tRNA-ribosyltransferase2.4.2.290.447
2aq8NAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.447
2eh4SAHDiphthine synthase/0.447
2r7nADP5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase/0.447
3k5dXLIBeta-secretase 13.4.23.460.447
3ohf3HFBeta-secretase 13.4.23.460.447
3qbwADPAnhydro-N-acetylmuramic acid kinase/0.447
3qowSAMHistone-lysine N-methyltransferase, H3 lysine-79 specific2.1.1.430.447
4buxF35Tankyrase-22.4.2.300.447
4feu537Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.447
4fhd0TTSpore photoproduct lyase/0.447
4kkyCAMCamphor 5-monooxygenase1.14.15.10.447
4kttSAMS-adenosylmethionine synthase isoform type-22.5.1.60.447
4n3l2FNProthrombin3.4.21.50.447
4na4A1RPoly(ADP-ribose) glycohydrolase3.2.1.1430.447
4nmbFADBifunctional protein PutA/0.447
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.447
5dr6SKEAurora kinase A2.7.11.10.447
1a72PADAlcohol dehydrogenase E chain1.1.1.10.446
1fxfMJIPhospholipase A2, major isoenzyme3.1.1.40.446
1t4v14AProthrombin3.4.21.50.446
1vzqSHYProthrombin3.4.21.50.446
1xs7MMIBeta-secretase 13.4.23.460.446
2fs4PZ1Renin3.4.23.150.446
2ji9TPWOxalyl-CoA decarboxylase4.1.1.80.446
2oc4IMHPurine nucleoside phosphorylase2.4.2.10.446
2y6fM9FIsopenicillin N synthase1.21.3.10.446
3nxoD2BDihydrofolate reductase1.5.1.30.446
3qtv06PProthrombin3.4.21.50.446
3rhrNDPCytosolic 10-formyltetrahydrofolate dehydrogenase1.5.1.60.446
4a8v2ANMajor pollen allergen Bet v 1-J/0.446
4ehv0SJMitogen-activated protein kinase 14/0.446
4j0v1H7Beta-secretase 13.4.23.460.446
4uogYYYNucleoside diphosphate kinase/0.446
5iubCLRAdenosine receptor A2a/0.446
1dr5NAPDihydrofolate reductase1.5.1.30.445
1dwxH4BNitric oxide synthase, inducible1.14.13.390.445
1g63FMNEpidermin decarboxylase4.1.10.445
1g7vPAI2-dehydro-3-deoxyphosphooctonate aldolase2.5.1.550.445
1gaqFADFerredoxin/0.445
1jwtBLIProthrombin3.4.21.50.445
1ofvFMNFlavodoxin/0.445
1paxDHQPoly [ADP-ribose] polymerase 12.4.2.300.445
1xh6R94cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
2ociTYCValacyclovir hydrolase3.10.445
3id8MRKGlucokinase2.7.1.20.445
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.445
3kfmKAIGlutamate receptor 4/0.445
3nxvD2FDihydrofolate reductase1.5.1.30.445
4a2aATPCell division protein FtsA/0.445
4pyoSAHCatechol O-methyltransferase2.1.1.60.445
5iu86DZAdenosine receptor A2a/0.445
1foaUD1Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase2.4.1.1010.444
1gj5130Prothrombin3.4.21.50.444
1kvkATPMevalonate kinase2.7.1.360.444
1og1TADT-cell ecto-ADP-ribosyltransferase 2/0.444
1riwOSCProthrombin3.4.21.50.444
1t85CAMCamphor 5-monooxygenase1.14.15.10.444
1xqp8HGN-glycosylase/DNA lyase/0.444
2b37NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
2cekN8TAcetylcholinesterase3.1.1.70.444
2ekaSAHDiphthine synthase/0.444
2f6rACOBifunctional coenzyme A synthase/0.444
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.444
3ab1FADFerredoxin--NADP reductase1.18.1.20.444
3fwfCAMCamphor 5-monooxygenase1.14.15.10.444
3h1vTK1Glucokinase2.7.1.20.444
3oxfSAHHistone-lysine N-methyltransferase SMYD32.1.1.430.444
3q2jCKIAminoglycoside 3'-phosphotransferase2.7.1.950.444
3v8s0HDRho-associated protein kinase 12.7.11.10.444
4f0fACPProbable serine/threonine-protein kinase roco42.7.11.10.444
4h0yNADIota toxin component Ia/0.444
4h9506UDihydrofolate reductase1.5.1.30.444
4ndnSAMS-adenosylmethionine synthase isoform type-22.5.1.60.444
4zhiADPKinesin-like protein KIF11/0.444
5aqzSGVHeat shock 70 kDa protein 1A/0.444
1ia3TQ5Dihydrofolate reductase1.5.1.30.443
1kiaSAMGlycine N-methyltransferase2.1.1.200.443
1rx1NAPDihydrofolate reductase1.5.1.30.443
1xddAAYIntegrin alpha-L/0.443
1z6tADPApoptotic protease-activating factor 1/0.443
2pmnK51Protein kinase 7/0.443
2v16C47Renin3.4.23.150.443
3bhrTHGThymidylate synthase/0.443
3exhTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.443
3exhTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.443
3vf60H6Glucokinase2.7.1.20.443
4adcPLPSuccinylornithine transaminase2.6.1.810.443
4b66NAPL-ornithine N(5)-monooxygenase/0.443
4h9753SDihydrofolate reductase1.5.1.30.443
4j531J4Serine/threonine-protein kinase PLK12.7.11.210.443
4jbxSK7Thymidine kinase/0.443
4jlt8PRCytochrome P450 2B41.14.14.10.443
4kwcSAHMethyltransferase domain family/0.443
4qnuGEKtRNA U34 carboxymethyltransferase/0.443
4ts7ADPPurine phosphoribosyltransferase (GpT-1)/0.443
4u3jGTPTubulin beta chain/0.443
1cdeGARPhosphoribosylglycinamide formyltransferase/0.442
1l8qADPChromosomal replication initiator protein DnaA/0.442
1yw9A84Methionine aminopeptidase 2/0.442
2ab8MTPAdenosine kinase2.7.1.200.442
2aouCQAHistamine N-methyltransferase2.1.1.80.442
2gfsPQBMitogen-activated protein kinase 14/0.442
2v13C40Renin3.4.23.150.442
2wnbC5PCMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 12.4.99.40.442
2wp5FADTrypanothione reductase/0.442
3dfrMTXDihydrofolate reductase1.5.1.30.442
3g0yP9A3-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.442
3hsnH4BNitric oxide synthase, brain1.14.13.390.442
3l0lHC3Nuclear receptor ROR-gamma/0.442
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.442
3smaACOFrbF/0.442
3sxjSAMPutative methyltransferase/0.442
4a9e3PFBromodomain-containing protein 2/0.442
4afeGGYSerine/threonine-protein kinase Nek22.7.11.10.442
4fwjFADLysine-specific histone demethylase 1B10.442
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
4gutFADLysine-specific histone demethylase 1B10.442
4nieNBHNuclear receptor ROR-gamma/0.442
4uohADPNucleoside diphosphate kinase/0.442
4ux6H4BNitric oxide synthase, inducible1.14.13.390.442
5ahsCOAAcyl-CoA dehydrogenase/0.442
1d3dBZTProthrombin3.4.21.50.441
1dr3HBIDihydrofolate reductase1.5.1.30.441
1f5fDHTSex hormone-binding globulin/0.441
1jdtMTAPurine nucleoside phosphorylase/0.441
1pd9CO4Dihydrofolate reductase1.5.1.30.441
1pfyMSPMethionine--tRNA ligase6.1.1.100.441
1rs7H4BNitric oxide synthase, brain1.14.13.390.441
1uyiPUZHeat shock protein HSP 90-alpha/0.441
1ypjUIBProthrombin3.4.21.50.441
2cv2GSUGlutamate--tRNA ligase6.1.1.170.441
2f8lSAMLmo1582 protein/0.441
2fhkMFNFormylmethanofuran--tetrahydromethanopterin formyltransferase2.3.1.1010.441
2qk8MTXDihydrofolate reductase/0.441
2v2zADP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.441
3dzl3OCPhenazine biosynthesis protein A/B/0.441
3ge7AFQQueuine tRNA-ribosyltransferase2.4.2.290.441
3kc3MK2MAP kinase-activated protein kinase 22.7.11.10.441
3o8aO8ADihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.441
3saz043Malate synthase G/0.441
3veu0GOBeta-secretase 13.4.23.460.441
4bb3KKAIsopenicillin N synthase1.21.3.10.441
4id9NADPutative UDP-glucose 4-epimerase/0.441
4lg5A1OAbscisic acid receptor PYL2/0.441
4nbl2J6Caspase-63.4.22.590.441
5c8d5ADProbable transcriptional regulator/0.441
5dstSAHProtein arginine N-methyltransferase 82.1.10.441
1pg0MODMethionine--tRNA ligase6.1.1.100.440
1u1d181Uridine phosphorylase2.4.2.30.440
1vi2NADQuinate/shikimate dehydrogenase/0.440
1yrcCAMCamphor 5-monooxygenase1.14.15.10.440
2aqhNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
2cig1DGDihydrofolate reductase1.5.1.30.440
2f4jVX6Tyrosine-protein kinase ABL12.7.10.20.440
2fjm073Tyrosine-protein phosphatase non-receptor type 13.1.3.480.440
3hyg099A disintegrin and metalloproteinase with thrombospondin motifs 53.4.240.440
3in6FMNUncharacterized protein/0.440
3nksACJProtoporphyrinogen oxidase1.3.3.40.440
3reoEUG(Iso)eugenol O-methyltransferase2.1.1.1460.440
4aoi4K0Hepatocyte growth factor receptor2.7.10.10.440
4cx3H4BNitric oxide synthase, brain1.14.13.390.440
4gqeH4BNitric oxide synthase, brain1.14.13.390.440
4l49CAMCamphor 5-monooxygenase1.14.15.10.440
5e5h0T1Succinyl-CoA:acetate CoA-transferase/0.440