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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2iw84SPCyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2iw84SPCyclin-dependent kinase 22.7.11.221.000
2iw94SPCyclin-dependent kinase 22.7.11.220.679
1oiyN41Cyclin-dependent kinase 22.7.11.220.654
1oi9N20Cyclin-dependent kinase 22.7.11.220.617
3r9dX6BCyclin-dependent kinase 22.7.11.220.599
1h1r6CPCyclin-dependent kinase 22.7.11.220.597
1oguST8Cyclin-dependent kinase 22.7.11.220.596
1ke6LS2Cyclin-dependent kinase 22.7.11.220.591
1h1s4SPCyclin-dependent kinase 22.7.11.220.586
3qqkX02Cyclin-dependent kinase 22.7.11.220.586
2w05FRTCyclin-dependent kinase 22.7.11.220.577
1e9hINRCyclin-dependent kinase 22.7.11.220.572
1oiuN76Cyclin-dependent kinase 22.7.11.220.572
3qu0X40Cyclin-dependent kinase 22.7.11.220.572
3qtzX42Cyclin-dependent kinase 22.7.11.220.569
2w06FRVCyclin-dependent kinase 22.7.11.220.568
2btsU32Cyclin-dependent kinase 22.7.11.220.567
3ral04ZCyclin-dependent kinase 22.7.11.220.565
4eor4SPCyclin-dependent kinase 22.7.11.220.565
1gih1PUCyclin-dependent kinase 22.7.11.220.564
4fkw62KCyclin-dependent kinase 22.7.11.220.564
1r78FMDCyclin-dependent kinase 22.7.11.220.562
3ddqRRCCyclin-dependent kinase 22.7.11.220.561
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.560
3sqq99ZCyclin-dependent kinase 22.7.11.220.560
4ez30S0Cyclin-dependent kinase 22.7.11.220.560
2iw6QQ2Cyclin-dependent kinase 22.7.11.220.559
3uli1N3Cyclin-dependent kinase 22.7.11.220.559
3qzhX69Cyclin-dependent kinase 22.7.11.220.558
3r9hZ67Cyclin-dependent kinase 22.7.11.220.558
3rjc06ZCyclin-dependent kinase 22.7.11.220.558
3rpv26ZCyclin-dependent kinase 22.7.11.220.558
3ddpRC8Cyclin-dependent kinase 22.7.11.220.557
4eok4SPCyclin-dependent kinase 22.7.11.220.555
3s1h56ZCyclin-dependent kinase 22.7.11.220.553
1ke7LS3Cyclin-dependent kinase 22.7.11.220.552
3dogNNNCyclin-dependent kinase 22.7.11.220.552
3rak03ZCyclin-dependent kinase 22.7.11.220.552
3rmf20ZCyclin-dependent kinase 22.7.11.220.552
1vyzN5BCyclin-dependent kinase 22.7.11.220.550
4qmpDKISerine/threonine-protein kinase 242.7.11.10.550
1di8DTQCyclin-dependent kinase 22.7.11.220.549
4acm7YGCyclin-dependent kinase 22.7.11.220.549
2w17I19Cyclin-dependent kinase 22.7.11.220.548
3qxoX65Cyclin-dependent kinase 22.7.11.220.548
4fx360KCyclin-dependent kinase 22.7.11.220.548
3roy22ZCyclin-dependent kinase 22.7.11.220.547
2wihP48Cyclin-dependent kinase 22.7.11.220.546
3rni21ZCyclin-dependent kinase 22.7.11.220.546
4bcpT3CCyclin-dependent kinase 22.7.11.220.546
2eufLQQCyclin-dependent kinase 62.7.11.220.545
2c5nCK8Cyclin-dependent kinase 22.7.11.220.544
2c6tDT5Cyclin-dependent kinase 22.7.11.220.544
3unk0BYCyclin-dependent kinase 22.7.11.220.544
1gij2PUCyclin-dependent kinase 22.7.11.220.543
1ke8LS4Cyclin-dependent kinase 22.7.11.220.543
3ezrEZRCyclin-dependent kinase 22.7.11.220.543
3qtxX43Cyclin-dependent kinase 22.7.11.220.543
1ke9LS5Cyclin-dependent kinase 22.7.11.220.542
1unlRRCCyclin-dependent-like kinase 52.7.11.10.542
3rk507ZCyclin-dependent kinase 22.7.11.220.540
1g5sI17Cyclin-dependent kinase 22.7.11.220.539
1vyw292Cyclin-dependent kinase 22.7.11.220.539
2b52D42Cyclin-dependent kinase 22.7.11.220.539
2btrU73Cyclin-dependent kinase 22.7.11.220.539
4fkpLS5Cyclin-dependent kinase 22.7.11.220.539
1fvv107Cyclin-dependent kinase 22.7.11.220.538
1ke5LS1Cyclin-dependent kinase 22.7.11.220.538
4bcnT9NCyclin-dependent kinase 22.7.11.220.538
3rk708ZCyclin-dependent kinase 22.7.11.220.537
4bcmT7ZCyclin-dependent kinase 22.7.11.220.537
1h1q2A6Cyclin-dependent kinase 22.7.11.220.536
2wotZZGTGF-beta receptor type-12.7.11.300.536
1y91CT9Cyclin-dependent kinase 22.7.11.220.535
3s0o50ZCyclin-dependent kinase 22.7.11.220.535
3py0SU9Cyclin-dependent kinase 22.7.11.220.534
3qzgX67Cyclin-dependent kinase 22.7.11.220.534
3r1sX73Cyclin-dependent kinase 22.7.11.220.534
4fki09KCyclin-dependent kinase 22.7.11.220.534
4fkt48KCyclin-dependent kinase 22.7.11.220.534
1urwI1PCyclin-dependent kinase 22.7.11.220.533
4fkr45KCyclin-dependent kinase 22.7.11.220.533
2a0cCK9Cyclin-dependent kinase 22.7.11.220.532
2b55D31Cyclin-dependent kinase 22.7.11.220.531
2x1nX1NCyclin-dependent kinase 22.7.11.220.531
3r6xX84Cyclin-dependent kinase 22.7.11.220.531
4eoi1ROCyclin-dependent kinase 22.7.11.220.531
3ql8X01Cyclin-dependent kinase 22.7.11.220.530
4erwSTUCyclin-dependent kinase 22.7.11.220.530
2xnbY8LCyclin-dependent kinase 22.7.11.220.529
1gii1PUCyclin-dependent kinase 22.7.11.220.528
1pyePM1Cyclin-dependent kinase 22.7.11.220.528
2r3lSCWCyclin-dependent kinase 22.7.11.220.528
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.528
3tnwF18Cyclin-dependent kinase 22.7.11.220.528
4fkq42KCyclin-dependent kinase 22.7.11.220.528
1w0xOLOCyclin-dependent kinase 22.7.11.220.527
2r64740Cyclin-dependent kinase 22.7.11.220.527
2uzlC94Cyclin-dependent kinase 22.7.11.220.527
2xmyCDKCyclin-dependent kinase 22.7.11.220.527
3lfnA27Cyclin-dependent kinase 22.7.11.220.527
3qtuX44Cyclin-dependent kinase 22.7.11.220.527
1pkdUCNCyclin-dependent kinase 22.7.11.220.526
1v1k3FPCyclin-dependent kinase 22.7.11.220.526
3pj8404Cyclin-dependent kinase 22.7.11.220.526
3r7eX88Cyclin-dependent kinase 22.7.11.220.526
1m2qMNXCasein kinase II subunit alpha2.7.11.10.525
1pxkCK3Cyclin-dependent kinase 22.7.11.220.525
3rk909ZCyclin-dependent kinase 22.7.11.220.525
4dgo0JWCasein kinase II subunit alpha2.7.11.10.525
4ek816KCyclin-dependent kinase 22.7.11.220.525
2bhhRYUCyclin-dependent kinase 22.7.11.220.524
2duv371Cyclin-dependent kinase 22.7.11.220.524
4bgh3I6Cyclin-dependent kinase 22.7.11.220.524
4eol1ROCyclin-dependent kinase 22.7.11.220.524
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.523
4eon1ROCyclin-dependent kinase 22.7.11.220.523
3r73X87Cyclin-dependent kinase 22.7.11.220.522
4cfnJYMCyclin-dependent kinase 22.7.11.220.522
2vu3LZECyclin-dependent kinase 22.7.11.220.521
3unj0BXCyclin-dependent kinase 22.7.11.220.520
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.520
5e8wSTUTGF-beta receptor type-12.7.11.300.520
1dm2HMDCyclin-dependent kinase 22.7.11.220.519
1xjdSTUProtein kinase C theta type2.7.11.130.519
2cchATPCyclin-dependent kinase 22.7.11.220.519
2vv9IM9Cyclin-dependent kinase 22.7.11.220.519
2wxvWXVCyclin-dependent kinase 22.7.11.220.518
3sw418KCyclin-dependent kinase 22.7.11.220.518
3ig7EFPCyclin-dependent kinase 22.7.11.220.517
3rm719ZCyclin-dependent kinase 22.7.11.220.517
4eos1ROCyclin-dependent kinase 22.7.11.220.517
2a4lRRCCyclin-dependent kinase 22.7.11.220.516
3my5RFZCyclin-dependent kinase 22.7.11.220.516
3r1qX75Cyclin-dependent kinase 22.7.11.220.516
4fks46KCyclin-dependent kinase 22.7.11.220.515
1h0w207Cyclin-dependent kinase 22.7.11.220.514
1oirHDYCyclin-dependent kinase 22.7.11.220.514
2uzdC85Cyclin-dependent kinase 22.7.11.220.514
3fz1B98Cyclin-dependent kinase 22.7.11.220.514
3qwkX62Cyclin-dependent kinase 22.7.11.220.514
4fkj11KCyclin-dependent kinase 22.7.11.220.514
1pxmCK5Cyclin-dependent kinase 22.7.11.220.513
2i40BLZCyclin-dependent kinase 22.7.11.220.513
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.513
3qqfX07Cyclin-dependent kinase 22.7.11.220.513
3qtrX36Cyclin-dependent kinase 22.7.11.220.513
4ek610KCyclin-dependent kinase 22.7.11.220.513
1p2a5BNCyclin-dependent kinase 22.7.11.220.512
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.512
2r3p3SCCyclin-dependent kinase 22.7.11.220.512
2vtnLZ7Cyclin-dependent kinase 22.7.11.220.512
4fko20KCyclin-dependent kinase 22.7.11.220.512
3o0g3O0Cyclin-dependent-like kinase 52.7.11.10.511
4bcoT6QCyclin-dependent kinase 22.7.11.220.511
1ckpPVBCyclin-dependent kinase 22.7.11.220.510
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.509
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.509
4ez50RSCyclin-dependent kinase 62.7.11.220.509
1v0oINRCell division control protein 2 homolog2.7.11.220.508
2uzoC62Cyclin-dependent kinase 22.7.11.220.508
3r7yZ04Cyclin-dependent kinase 22.7.11.220.508
1h1pCMGCyclin-dependent kinase 22.7.11.220.507
1oitHDTCyclin-dependent kinase 22.7.11.220.507
3ezvEZVCyclin-dependent kinase 22.7.11.220.507
3qruX19Cyclin-dependent kinase 22.7.11.220.507
3qziX72Cyclin-dependent kinase 22.7.11.220.507
2bkzSBCCyclin-dependent kinase 22.7.11.220.506
2c4g514Cyclin-dependent kinase 22.7.11.220.506
2pvnP63Casein kinase II subunit alpha2.7.11.10.506
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.506
3rpy27ZCyclin-dependent kinase 22.7.11.220.506
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.506
2uzeC95Cyclin-dependent kinase 22.7.11.220.505
3r8lZ30Cyclin-dependent kinase 22.7.11.220.505
3raiX85Cyclin-dependent kinase 22.7.11.220.505
3nux3NVCyclin-dependent kinase 62.7.11.220.503
3qtqX35Cyclin-dependent kinase 22.7.11.220.503
3bhtMFRCyclin-dependent kinase 22.7.11.220.502
1vjy460TGF-beta receptor type-12.7.11.300.501
3iggEFQCyclin-dependent kinase 22.7.11.220.501
3qxpX64Cyclin-dependent kinase 22.7.11.220.501
3sw719KCyclin-dependent kinase 22.7.11.220.500
4fkg4CKCyclin-dependent kinase 22.7.11.220.500
3r71X86Cyclin-dependent kinase 22.7.11.220.499
3r7iX9ICyclin-dependent kinase 22.7.11.220.499
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.499
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.498
2r3jSCJCyclin-dependent kinase 22.7.11.220.498
2wpa889Cyclin-dependent kinase 22.7.11.220.498
1oiqHDUCyclin-dependent kinase 22.7.11.220.497
2xikJ60Serine/threonine-protein kinase 252.7.11.10.497
3rkb12ZCyclin-dependent kinase 22.7.11.220.497
4qmzB49Serine/threonine-protein kinase 242.7.11.10.497
1ykr628Cyclin-dependent kinase 22.7.11.220.496
2c6iDT1Cyclin-dependent kinase 22.7.11.220.496
2uznC96Cyclin-dependent kinase 22.7.11.220.496
3r28XA0Cyclin-dependent kinase 22.7.11.220.496
3r8zZ63Cyclin-dependent kinase 22.7.11.220.496
3rm618ZCyclin-dependent kinase 22.7.11.220.496
1fvt106Cyclin-dependent kinase 22.7.11.220.495
3at4CCKCasein kinase II subunit alpha2.7.11.10.495
4dgnLU2Casein kinase II subunit alpha2.7.11.10.495
4eomATPCyclin-dependent kinase 22.7.11.220.495
1pxpCK8Cyclin-dependent kinase 22.7.11.220.494
2uzbC75Cyclin-dependent kinase 22.7.11.220.494
3r9oZ71Cyclin-dependent kinase 22.7.11.220.494
3s2pPMUCyclin-dependent kinase 22.7.11.220.494
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.493
3lfqA28Cyclin-dependent kinase 22.7.11.220.493
3rpo24ZCyclin-dependent kinase 22.7.11.220.493
1b39ATPCyclin-dependent kinase 22.7.11.220.492
4eop1ROCyclin-dependent kinase 22.7.11.220.492
4gfo0X2Non-receptor tyrosine-protein kinase TYK22.7.10.20.492
4nj32KDCyclin-dependent kinase 22.7.11.220.492
2vthLZ2Cyclin-dependent kinase 22.7.11.220.491
1pxlCK4Cyclin-dependent kinase 22.7.11.220.490
1pxoCK7Cyclin-dependent kinase 22.7.11.220.490
3gxlQIGTGF-beta receptor type-12.7.11.300.490
4jqeANPCasein kinase II subunit alpha2.7.11.10.490
4lyn1YGCyclin-dependent kinase 22.7.11.220.490
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.490
1v0pPVBCell division control protein 2 homolog2.7.11.220.489
3be9P04Casein kinase II subunit alpha2.7.11.10.489
3ggfGVDSerine/threonine-protein kinase 26/0.488
3nup3NUCyclin-dependent kinase 62.7.11.220.488
3r1yX76Cyclin-dependent kinase 22.7.11.220.488
1eh4IC1Casein kinase I homolog 12.7.11.10.487
3r83Z14Cyclin-dependent kinase 22.7.11.220.487
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.487
4g170VNCasein kinase I isoform gamma-32.7.11.10.487
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.486
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.485
3gubGUBDeath-associated protein kinase 12.7.11.10.485
2vuw5IDSerine/threonine-protein kinase haspin2.7.11.10.484
3axwTIDCasein kinase II subunit alpha2.7.11.10.484
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.484
4i22IREEpidermal growth factor receptor2.7.10.10.484
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.483
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.483
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.483
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.483
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.482
4bgg844Activin receptor type-12.7.11.300.482
2vttLZDCyclin-dependent kinase 22.7.11.220.481
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.481
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.481
4c4f7CEDual specificity protein kinase TTK2.7.12.10.481
4jr7GNPCasein kinase II subunit alpha2.7.11.10.481
1finATPCyclin-dependent kinase 22.7.11.220.480
2pmlANPUncharacterized protein/0.480
1gy3ATPCyclin-dependent kinase 22.7.11.220.479
2b9jADPMitogen-activated protein kinase FUS32.7.11.240.479
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.479
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.479
4grb0XGCasein kinase II subunit alpha2.7.11.10.479
1b38ATPCyclin-dependent kinase 22.7.11.220.478
1e1xNW1Cyclin-dependent kinase 22.7.11.220.478
2izsBRQCasein kinase I isoform gamma-32.7.11.10.478
2r3iSCFCyclin-dependent kinase 22.7.11.220.478
2xa4AZ5Tyrosine-protein kinase JAK2/0.478
3qd33Q53-phosphoinositide-dependent protein kinase 12.7.11.10.478
3v8t477Tyrosine-protein kinase ITK/TSK2.7.10.20.478
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.477
2f2cAP9Cyclin-dependent kinase 62.7.11.220.477
3at3ATKCasein kinase II subunit alpha2.7.11.10.477
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.477
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.477
4dgmAGICasein kinase II subunit alpha2.7.11.10.477
4gmy0X5Tyrosine-protein kinase JAK2/0.477
1unhIXMCyclin-dependent-like kinase 52.7.11.10.476
2bheBRYCyclin-dependent kinase 22.7.11.220.476
2zdt46CMitogen-activated protein kinase 102.7.11.240.476
3mvl38PMitogen-activated protein kinase 14/0.476
3r7vZ02Cyclin-dependent kinase 22.7.11.220.476
4anmWULCasein kinase II subunit alpha2.7.11.10.476
4gii0X6Non-receptor tyrosine-protein kinase TYK22.7.10.20.476
2izrBRKCasein kinase I isoform gamma-32.7.11.10.475
2pvhP19Casein kinase II subunit alpha2.7.11.10.475
2pvlP55Casein kinase II subunit alpha2.7.11.10.475
2r3gSC9Cyclin-dependent kinase 22.7.11.220.475
3a7jADPSerine/threonine-protein kinase 242.7.11.10.475
3q9xEMOCasein kinase II subunit alpha2.7.11.10.475
3ti1B49Cyclin-dependent kinase 22.7.11.220.475
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.475
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.474
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.474
2r3kSCQCyclin-dependent kinase 22.7.11.220.473
2w1hL0FCyclin-dependent kinase 22.7.11.220.473
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.473
3l8p0CEAngiopoietin-1 receptor2.7.10.10.473
3sheI85MAP kinase-activated protein kinase 32.7.11.10.473
4hvh19RTyrosine-protein kinase JAK32.7.10.20.473
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.473
4yuqKS1Calmodulin-like domain protein kinase/0.473
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.472
2j9mPY8Cyclin-dependent kinase 22.7.11.220.472
3qzfX66Cyclin-dependent kinase 22.7.11.220.472
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.472
4bcqTJFCyclin-dependent kinase 22.7.11.220.472
1aq1STUCyclin-dependent kinase 22.7.11.220.471
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.471
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.471
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.470
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.470
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.470
3qrtX14Cyclin-dependent kinase 22.7.11.220.470
3qtwX3ACyclin-dependent kinase 22.7.11.220.470
3qwjX6ACyclin-dependent kinase 22.7.11.220.470
1m2pHNACasein kinase II subunit alpha2.7.11.10.469
3r7uX96Cyclin-dependent kinase 22.7.11.220.469
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.469
4j97ACPFibroblast growth factor receptor 2/0.469
1lp4ANPCasein kinase II subunit alpha2.7.11.10.468
2r3r6SCCyclin-dependent kinase 22.7.11.220.468
4bchT7ZCyclin-dependent kinase 92.7.11.220.468
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.468
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.468
5cvhADPCasein kinase II subunit alpha2.7.11.10.468
2b9iADPMitogen-activated protein kinase FUS32.7.11.240.467
2hog710Serine/threonine-protein kinase Chk12.7.11.10.467
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.467
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.467
3qx2X63Cyclin-dependent kinase 22.7.11.220.467
4l521ULMitogen-activated protein kinase kinase kinase 72.7.11.250.467
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.466
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.466
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.466
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.466
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.466
4fv9E71Mitogen-activated protein kinase 12.7.11.240.466
2c6kDT2Cyclin-dependent kinase 22.7.11.220.465
3zm422TDual specificity mitogen-activated protein kinase kinase 12.7.12.20.465
4riyADPEpidermal growth factor receptor2.7.10.10.465
2b54D05Cyclin-dependent kinase 22.7.11.220.464
3ttjJBIMitogen-activated protein kinase 102.7.11.240.464
4c4jX21Dual specificity protein kinase TTK2.7.12.10.464
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.464
4r8qADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.464
3qqlX03Cyclin-dependent kinase 22.7.11.220.463
3rvg17PTyrosine-protein kinase JAK2/0.463
5auwQUEDeath-associated protein kinase 12.7.11.10.463
1h0vUN4Cyclin-dependent kinase 22.7.11.220.462
1w8cN69Cyclin-dependent kinase 22.7.11.220.462
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.462
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.462
3eljGS7Mitogen-activated protein kinase 82.7.11.240.462
3i60E86Mitogen-activated protein kinase 12.7.11.240.462
3iok1P6Tyrosine-protein kinase JAK2/0.462
3mtlFEFCyclin-dependent kinase 162.7.11.220.462
3qx4X4BCyclin-dependent kinase 22.7.11.220.462
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.462
3v5j0F2Tyrosine-protein kinase ITK/TSK2.7.10.20.462
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.462
4qnaX11Serine/threonine-protein kinase 242.7.11.10.462
1ol5ADPAurora kinase A2.7.11.10.461
1xddAAYIntegrin alpha-L/0.461
2zv2609Calcium/calmodulin-dependent protein kinase kinase 22.7.11.170.461
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.461
3le62BZCyclin-dependent kinase 22.7.11.220.461
4btjADPTau-tubulin kinase 12.7.11.10.461
4bznUGXSerine/threonine-protein kinase pim-12.7.11.10.461
4hvg19QTyrosine-protein kinase JAK32.7.10.20.461
4kb81QNCasein kinase I isoform delta2.7.11.10.461
5dosATPAurora kinase A2.7.11.10.461
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.460
3nynSGVG protein-coupled receptor kinase 62.7.11.160.460
3s00Z60Cyclin-dependent kinase 22.7.11.220.460
4c4h7RODual specificity protein kinase TTK2.7.12.10.460
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.460
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.460
4n6z2HWSerine/threonine-protein kinase pim-12.7.11.10.460
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.459
2j0j4STFocal adhesion kinase 12.7.10.20.459
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.459
3c4zADPRhodopsin kinase/0.459
3pxyJWSCyclin-dependent kinase 22.7.11.220.459
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.459
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.459
4lopSB4Mitogen-activated protein kinase 14/0.459
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.459
5drdATPAurora kinase A2.7.11.10.459
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.458
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.458
2vtlLZ5Cyclin-dependent kinase 22.7.11.220.458
2vtqLZACyclin-dependent kinase 22.7.11.220.458
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.458
3mfrANPPeripheral plasma membrane protein CASK2.7.11.10.458
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.458
4hge15VTyrosine-protein kinase JAK2/0.458
4kba1QMCasein kinase I isoform delta2.7.11.10.458
5dr6SKEAurora kinase A2.7.11.10.458
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.457
2c5yMTWCyclin-dependent kinase 22.7.11.220.457
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.457
2chlDKICasein kinase I isoform gamma-32.7.11.10.457
2vagV25Dual specificity protein kinase CLK12.7.12.10.457
3hztJ60Calmodulin-like domain protein kinase isoform 3/0.457
3r8uZ31Cyclin-dependent kinase 22.7.11.220.457
4b99R4LMitogen-activated protein kinase 72.7.11.240.457
4hgt15GCasein kinase I isoform delta2.7.11.10.457
4ogrADNCyclin-dependent kinase 92.7.11.220.457
4wboANWRhodopsin kinase/0.457
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.457
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.456
2j0m4STFocal adhesion kinase 12.7.10.20.456
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.456
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.456
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.456
4aua4AUCyclin-dependent kinase 62.7.11.220.456
4bdfH3RSerine/threonine-protein kinase Chk22.7.11.10.456
4btjATPTau-tubulin kinase 12.7.11.10.456
4gub0Y4Casein kinase II subunit alpha2.7.11.10.456
4hvi19STyrosine-protein kinase JAK32.7.10.20.456
4kd11QKCyclin-dependent kinase 22.7.11.220.456
4qmySTUSerine/threonine-protein kinase 242.7.11.10.456
1jstATPCyclin-dependent kinase 22.7.11.220.455
1m2rMNYCasein kinase II subunit alpha2.7.11.10.455
2c6mDT5Cyclin-dependent kinase 22.7.11.220.455
2gdo12CSerine/threonine-protein kinase Chk12.7.11.10.455
3kc3MK2MAP kinase-activated protein kinase 22.7.11.10.455
3mfuANPPeripheral plasma membrane protein CASK2.7.11.10.455
3r8vZ62Cyclin-dependent kinase 22.7.11.220.455
3wblPDYCyclin-dependent kinase 22.7.11.220.455
4aqc88ATyrosine-protein kinase JAK2/0.455
4oacADPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.455
5cshATPCasein kinase II subunit alpha2.7.11.10.455
1q5kTMUGlycogen synthase kinase-3 beta2.7.11.260.454
2b7aIZATyrosine-protein kinase JAK2/0.454
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.454
2dwbANPAurora kinase A2.7.11.10.454
3gu6ADPDeath-associated protein kinase 12.7.11.10.454
3hmm855TGF-beta receptor type-12.7.11.300.454
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.454
1hckATPCyclin-dependent kinase 22.7.11.220.453
1qmzATPCyclin-dependent kinase 22.7.11.220.453
1uu3LY43-phosphoinositide-dependent protein kinase 12.7.11.10.453
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.453
2r5tANPSerine/threonine-protein kinase Sgk12.7.11.10.453
3a7hATPSerine/threonine-protein kinase 242.7.11.10.453
3t8oATPRhodopsin kinase/0.453
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.453
5aniES4Cyclin-dependent kinase 22.7.11.220.453
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.452
3el51UNGag-Pol polyprotein/0.452
3ormAGSSerine/threonine protein kinase/0.452
3qd03Q43-phosphoinositide-dependent protein kinase 12.7.11.10.452
3tiz3TICyclin-dependent kinase 22.7.11.220.452
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.452
2r3mSCXCyclin-dependent kinase 22.7.11.220.451
2r3o2SCCyclin-dependent kinase 22.7.11.220.451
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.451
3m42HGFMAP kinase-activated protein kinase 22.7.11.10.451
3mtfA3FActivin receptor type-12.7.11.300.451
3qyw6PBMitogen-activated protein kinase 12.7.11.240.451
3uimANPBRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 12.7.10.10.451
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.451
4k33ACPFibroblast growth factor receptor 32.7.10.10.451
4zseANPEpidermal growth factor receptor2.7.10.10.451
1o6yACPSerine/threonine-protein kinase PknB2.7.11.10.450
1uv5BRWGlycogen synthase kinase-3 beta2.7.11.260.450
2c69CT8Cyclin-dependent kinase 22.7.11.220.450
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.450
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.450
3amaSKEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.450
3pe2E1BCasein kinase II subunit alpha2.7.11.10.450
3rpr25ZCyclin-dependent kinase 22.7.11.220.450
3v3vMYUMitogen-activated protein kinase 82.7.11.240.450
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.450
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.450
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.450
4krcAGSCyclin-dependent protein kinase PHO852.7.11.220.450
4mf029ZTyrosine-protein kinase ITK/TSK2.7.10.20.450
1om1IQACasein kinase II subunit alpha2.7.11.10.449
1pkgADPMast/stem cell growth factor receptor Kit2.7.10.10.449
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.449
3lfsA07Cyclin-dependent kinase 22.7.11.220.449
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.449
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
4c4g7RODual specificity protein kinase TTK2.7.12.10.449
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.449
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.449
4jia1K3Tyrosine-protein kinase JAK2/0.449
4k0y1OASerine/threonine-protein kinase pim-12.7.11.10.449
5auvAGIDeath-associated protein kinase 12.7.11.10.449
1iwjCAMCamphor 5-monooxygenase1.14.15.10.448
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.448
2xngA0HAurora kinase A2.7.11.10.448
3lq5SLQCyclin-dependent kinase 92.7.11.220.448
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.448
4fv3EK6Mitogen-activated protein kinase 12.7.11.240.448
4gvjADPNon-receptor tyrosine-protein kinase TYK22.7.10.20.448
4ivc1J6Tyrosine-protein kinase JAK1/0.448
1csnATPCasein kinase I homolog 12.7.11.10.447
1dawANPCasein kinase II subunit alpha2.7.11.10.447
1hpxKNIGag-Pol polyprotein/0.447
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.447
3bgpVX1Serine/threonine-protein kinase pim-12.7.11.10.447
3nga3NGCasein kinase II subunit alpha2.7.11.10.447
3q43D66M1 family aminopeptidase3.4.110.447
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.447
3wi6YRZMAP kinase-activated protein kinase 22.7.11.10.447
3zh8C58Protein kinase C iota type2.7.11.130.447
4dn5AGSMitogen-activated protein kinase kinase kinase 142.7.11.250.447
4e4m0NHTyrosine-protein kinase JAK2/0.447
4fv5EK9Mitogen-activated protein kinase 12.7.11.240.447
5cu6ATPCasein kinase II subunit alpha2.7.11.10.447
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.446
2vtsLZCCyclin-dependent kinase 22.7.11.220.446
2xiyXIYSerine/threonine-protein kinase pim-12.7.11.10.446
3wowANPCasein kinase II subunit alpha2.7.11.10.446
4aguD15Cyclin-dependent kinase-like 1/0.446
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.446
4cp4CAMCamphor 5-monooxygenase1.14.15.10.446
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.446
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.446
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.446
4qmlANPSerine/threonine-protein kinase 242.7.11.10.446
5av4GENDeath-associated protein kinase 12.7.11.10.446
5e8xSTUTGF-beta receptor type-12.7.11.300.446
2b53D23Cyclin-dependent kinase 22.7.11.220.445
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.445
2qkrIXMCdc2-like CDK2/CDC28 like protein kinase/0.445
2vtrLZBCyclin-dependent kinase 22.7.11.220.445
2yfeYFEPeroxisome proliferator-activated receptor gamma/0.445
3lqfNADGalactitol dehydrogenase/0.445
4c61LMMTyrosine-protein kinase JAK2/0.445
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.445
4iirANPSerine/threonine-protein kinase PRP4 homolog2.7.11.10.445
4ivb1J5Tyrosine-protein kinase JAK1/0.445
4kwi1TJReductase homolog/0.445
4mq22C4Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.445
1rx8NAPDihydrofolate reductase1.5.1.30.444
1tezFADDeoxyribodipyrimidine photo-lyase4.1.99.30.444
1uu9BI33-phosphoinositide-dependent protein kinase 12.7.11.10.444
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.444
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.444
2h96893Mitogen-activated protein kinase 82.7.11.240.444
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.444
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.444
3cy3JN5Serine/threonine-protein kinase pim-12.7.11.10.444
3l1sZ92Glycogen synthase kinase-3 beta2.7.11.260.444
3lixE17Protease/0.444
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.444
3uzp0CKCasein kinase I isoform delta2.7.11.10.444
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.444
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.444
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.444
4hgl0YOCasein kinase I isoform gamma-32.7.11.10.444
1jpaANPEphrin type-B receptor 22.7.10.10.443
1ungALHCyclin-dependent-like kinase 52.7.11.10.443
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.443
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.443
3lltANPProtein serine/threonine kinase-1/0.443
3orkAGSSerine/threonine protein kinase/0.443
3u4uLNHCasein kinase II subunit alpha2.7.11.10.443
4bhzZ0BDual specificity protein kinase TTK2.7.12.10.443
4g6oE28Mitogen-activated protein kinase 12.7.11.240.443
4hnf16WCasein kinase I isoform delta2.7.11.10.443
4iva1J5Tyrosine-protein kinase JAK2/0.443
4jajXU1Aurora kinase A2.7.11.10.443
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.443
5dr2ATPAurora kinase A2.7.11.10.443
1tqmANPRIO-type serine/threonine-protein kinase Rio22.7.11.10.442
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.442
2jkkBI9Focal adhesion kinase 12.7.10.20.442
2pe039Z3-phosphoinositide-dependent protein kinase 12.7.11.10.442
2pwcG3GGag-Pol polyprotein3.4.23.160.442
3a62STURibosomal protein S6 kinase beta-12.7.11.10.442
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.442
4ewhT77Activated CDC42 kinase 1/0.442
4ezl0SEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
4gu94GUFocal adhesion kinase 12.7.10.20.442
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.442
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.441
1qnfFADDeoxyribodipyrimidine photo-lyase4.1.99.30.441
1udaUFGUDP-glucose 4-epimerase5.1.3.20.441
1yi3LY2Serine/threonine-protein kinase pim-12.7.11.10.441
2bdjHETProto-oncogene tyrosine-protein kinase Src2.7.10.20.441
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.441
3bgcLJHGag-Pol polyprotein3.4.23.160.441
3c4eC4ESerine/threonine-protein kinase pim-12.7.11.10.441
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.441
3nlb5BESerine/threonine-protein kinase Chk12.7.11.10.441
3rzb02ZCyclin-dependent kinase 22.7.11.220.441
4fyo0VFTyrosine-protein kinase SYK2.7.10.20.441
4tuvCPZCytochrome P450 1191.140.441
4wsqKSAAP2-associated protein kinase 12.7.11.10.441
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.440
1xl2189Gag-Pol polyprotein3.4.23.160.440
2ckeIQUDeath-associated protein kinase 2/0.440
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.440
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.440
2ycfYCFSerine/threonine-protein kinase Chk22.7.11.10.440
3bhh5CPCalcium/calmodulin-dependent protein kinase type II subunit beta2.7.11.170.440
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.440
4ft3H1KSerine/threonine-protein kinase Chk12.7.11.10.440
4fv4EK7Mitogen-activated protein kinase 12.7.11.240.440
4fv6E57Mitogen-activated protein kinase 12.7.11.240.440
4i0s1B5Tyrosine-protein kinase SYK2.7.10.20.440
4jboWPHAurora kinase A2.7.11.10.440
4qpmADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.440
5auxKMPDeath-associated protein kinase 12.7.11.10.440
5dt3ATPAurora kinase A2.7.11.10.440