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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4deg0JJHepatocyte growth factor receptor2.7.10.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
4deg0JJHepatocyte growth factor receptor2.7.10.11.000
4gg70J8Hepatocyte growth factor receptor2.7.10.10.660
4ap7F47Hepatocyte growth factor receptor2.7.10.10.651
3zze6XPHepatocyte growth factor receptor2.7.10.10.619
3zxzKRWHepatocyte growth factor receptor2.7.10.10.612
2wgjVGHHepatocyte growth factor receptor2.7.10.10.605
3zc5W9ZHepatocyte growth factor receptor2.7.10.10.601
4gg50J3Hepatocyte growth factor receptor2.7.10.10.594
4aoi4K0Hepatocyte growth factor receptor2.7.10.10.577
3a4pDFQHepatocyte growth factor receptor2.7.10.10.541
3zbx6XEHepatocyte growth factor receptor2.7.10.10.533
4kb81QOCasein kinase I isoform delta2.7.11.10.516
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.512
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.508
2vagV25Dual specificity protein kinase CLK12.7.12.10.507
3c50ADPRhodopsin kinase/0.498
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.498
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.498
1u3dFADCryptochrome-1/0.494
2wkmPFYHepatocyte growth factor receptor2.7.10.10.494
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.491
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.491
3c4zADPRhodopsin kinase/0.490
4l9i8PRRhodopsin kinase/0.490
5e8wSTUTGF-beta receptor type-12.7.11.300.490
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.488
1ir3ANPInsulin receptor2.7.10.10.488
4dymIYZActivin receptor type-12.7.11.300.488
3i81EBIInsulin-like growth factor 1 receptor2.7.10.10.486
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.486
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.485
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.484
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.484
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.483
3iw4LW4Protein kinase C alpha type2.7.11.130.482
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.482
2yeiXQIHeat shock protein HSP 90-alpha/0.481
3bqr4RBDeath-associated protein kinase 3/0.481
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.481
4iwd1JCHepatocyte growth factor receptor2.7.10.10.481
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.480
2j4z626Aurora kinase A2.7.11.10.480
4gu94GUFocal adhesion kinase 12.7.10.20.480
4lm5Q17Serine/threonine-protein kinase pim-12.7.11.10.480
4xgxADPFAD:protein FMN transferase/0.480
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.479
4ewhT77Activated CDC42 kinase 1/0.479
1rfvADPPyridoxal kinase2.7.1.350.478
2bkzSBCCyclin-dependent kinase 22.7.11.220.478
3hztJ60Calmodulin-like domain protein kinase isoform 3/0.478
4lopSB4Mitogen-activated protein kinase 14/0.478
1u4dDBQActivated CDC42 kinase 1/0.477
2fwzH71Heat shock protein HSP 90-alpha/0.477
2iw94SPCyclin-dependent kinase 22.7.11.220.477
3m42HGFMAP kinase-activated protein kinase 22.7.11.10.477
3zh8C58Protein kinase C iota type2.7.11.130.477
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.477
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.477
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.477
1aq1STUCyclin-dependent kinase 22.7.11.220.476
1s6qTPBGag-Pol polyprotein2.7.7.490.476
2c5nCK8Cyclin-dependent kinase 22.7.11.220.476
2ckeIQUDeath-associated protein kinase 2/0.476
2vgoAD5Aurora kinase B-A2.7.11.10.476
3c4xATPRhodopsin kinase/0.476
3eyhIZATyrosine-protein kinase JAK1/0.476
4gfo0X2Non-receptor tyrosine-protein kinase TYK22.7.10.20.476
5auvAGIDeath-associated protein kinase 12.7.11.10.476
3bheBZNGag-Pol polyprotein3.4.23.160.475
3vetADPnebramycin 5' synthase6.1.2.20.475
4c02TAKActivin receptor type-12.7.11.300.475
4fv6E57Mitogen-activated protein kinase 12.7.11.240.475
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.474
2xa4AZ5Tyrosine-protein kinase JAK2/0.473
4y95746Tyrosine-protein kinase/0.473
1e9hINRCyclin-dependent kinase 22.7.11.220.472
1uy9PU6Heat shock protein HSP 90-alpha/0.472
2x1nX1NCyclin-dependent kinase 22.7.11.220.472
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.472
5av2KMPDeath-associated protein kinase 12.7.11.10.472
1kl2FONSerine hydroxymethyltransferase/0.471
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.471
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.471
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.471
4ix6ADPUncharacterized protein/0.471
4yhjAN2G protein-coupled receptor kinase 42.7.11.160.471
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.470
2uzlC94Cyclin-dependent kinase 22.7.11.220.470
2vmyFFOSerine hydroxymethyltransferase/0.470
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.470
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.470
4krcAGSCyclin-dependent protein kinase PHO852.7.11.220.470
4uyg73BBromodomain-containing protein 2/0.470
1rbyKEUTrifunctional purine biosynthetic protein adenosine-32.1.2.20.469
3kgaLX9MAP kinase-activated protein kinase 22.7.11.10.469
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.469
4l9q9TPSerum albumin/0.469
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.468
1r2jFADFkbI/0.468
2fwyH64Heat shock protein HSP 90-alpha/0.468
2xikJ60Serine/threonine-protein kinase 252.7.11.10.468
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.468
4jqeANPCasein kinase II subunit alpha2.7.11.10.468
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.467
2cppCAMCamphor 5-monooxygenase1.14.15.10.467
2jedLG8Protein kinase C theta type2.7.11.130.467
3bgzVX3Serine/threonine-protein kinase pim-12.7.11.10.467
3mtfA3FActivin receptor type-12.7.11.300.467
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.467
1ol7ADPAurora kinase A2.7.11.10.466
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.466
2j2iLY4Serine/threonine-protein kinase pim-12.7.11.10.466
2ok7FADFerredoxin--NADP reductase, apicoplast/0.466
3gubGUBDeath-associated protein kinase 12.7.11.10.466
3q44D50M1 family aminopeptidase3.4.110.466
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.466
4qmzB49Serine/threonine-protein kinase 242.7.11.10.466
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.466
5av4GENDeath-associated protein kinase 12.7.11.10.466
5cvfATPCasein kinase II subunit alpha2.7.11.10.466
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.465
2jkqVG8Focal adhesion kinase 12.7.10.20.465
3s0o50ZCyclin-dependent kinase 22.7.11.220.465
4fnyI3KALK tyrosine kinase receptor2.7.10.10.465
5hidB1ESerine/threonine-protein kinase B-raf2.7.11.10.465
1uycPU7Heat shock protein HSP 90-alpha/0.464
1wvxBD4Death-associated protein kinase 12.7.11.10.464
2hr8SAHDiphthine synthase/0.464
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.464
3gu83GUDeath-associated protein kinase 12.7.11.10.464
4loqSB4Mitogen-activated protein kinase 14/0.464
5aaaVGHALK tyrosine kinase receptor2.7.10.10.464
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.463
2iw84SPCyclin-dependent kinase 22.7.11.220.463
2izsBRQCasein kinase I isoform gamma-32.7.11.10.463
2v7a627Tyrosine-protein kinase ABL12.7.10.20.463
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.463
3r02UNMSerine/threonine-protein kinase pim-12.7.11.10.463
3uixQ17Serine/threonine-protein kinase pim-12.7.11.10.463
4im01FVSerine/threonine-protein kinase TBK12.7.11.10.463
4yuqKS1Calmodulin-like domain protein kinase/0.463
5auzGENDeath-associated protein kinase 12.7.11.10.463
1o6yACPSerine/threonine-protein kinase PknB2.7.11.10.462
2h55DZ8Heat shock protein HSP 90-alpha/0.462
3a7jADPSerine/threonine-protein kinase 242.7.11.10.462
3at4CCKCasein kinase II subunit alpha2.7.11.10.462
3tneRITCandidapepsin-13.4.23.240.462
4c4jX21Dual specificity protein kinase TTK2.7.12.10.462
4fob0USALK tyrosine kinase receptor2.7.10.10.462
4foc0UUALK tyrosine kinase receptor2.7.10.10.462
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.462
4looSB4Mitogen-activated protein kinase 14/0.462
1bsvNDPGDP-L-fucose synthase/0.461
1g5sI17Cyclin-dependent kinase 22.7.11.220.461
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.461
2owuSAHDiphthine synthase/0.461
3uyt0CKCasein kinase I isoform delta2.7.11.10.461
3w0pADPHygromycin-B 4-O-kinase2.7.1.1630.461
4aacAAVMitogen-activated protein kinase 14/0.461
4kbc1QJCasein kinase I isoform delta2.7.11.10.461
4z9rNADOmega-3 polyunsaturated fatty acid synthase subunit PfaD/0.461
5auwQUEDeath-associated protein kinase 12.7.11.10.461
1di8DTQCyclin-dependent kinase 22.7.11.220.460
1fxsNAPGDP-L-fucose synthase/0.460
1u54ACPActivated CDC42 kinase 1/0.460
1unlRRCCyclin-dependent-like kinase 52.7.11.10.460
2ijmATPFocal adhesion kinase 12.7.10.20.460
2vv9IM9Cyclin-dependent kinase 22.7.11.220.460
2w1eL0EAurora kinase A2.7.11.10.460
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.460
2ydkYDKSerine/threonine-protein kinase Chk12.7.11.10.460
3hvcGG5Mitogen-activated protein kinase 14/0.460
3igoANPCalmodulin-domain protein kinase 1, putative/0.460
3krwBA1Beta-adrenergic receptor kinase 12.7.11.150.460
4b99R4LMitogen-activated protein kinase 72.7.11.240.460
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.460
4c62XWWTyrosine-protein kinase JAK2/0.460
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.460
3uzaT4GAdenosine receptor A2a/0.460
1e7qNAPGDP-L-fucose synthase/0.459
1k7fIAVTryptophan synthase alpha chain/0.459
2c6tDT5Cyclin-dependent kinase 22.7.11.220.459
2izrBRKCasein kinase I isoform gamma-32.7.11.10.459
2x3nFADProbable FAD-dependent monooxygenase/0.459
3fzr3JZProtein-tyrosine kinase 2-beta2.7.10.20.459
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.459
3oom507Activin receptor type-12.7.11.300.459
4eutBX7Serine/threonine-protein kinase TBK12.7.11.10.459
4grb0XGCasein kinase II subunit alpha2.7.11.10.459
4mwhATPCasein kinase II subunit alpha2.7.11.10.459
1r78FMDCyclin-dependent kinase 22.7.11.220.458
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.458
2d29FADAcyl-CoA dehydrogenase/0.458
2ojg19AMitogen-activated protein kinase 12.7.11.240.458
2pziAXXSerine/threonine-protein kinase PknG2.7.11.10.458
2wotZZGTGF-beta receptor type-12.7.11.300.458
3e5aVX6Aurora kinase A2.7.11.10.458
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.458
3lctADPALK tyrosine kinase receptor2.7.10.10.458
3lf0ATPNitrogen regulatory protein P-II/0.458
3qaiXNNKetohexokinase/0.458
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.458
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.458
3we45FIRibosomal protein S6 kinase beta-12.7.11.10.458
4at3LTIBDNF/NT-3 growth factors receptor2.7.10.10.458
4bcpT3CCyclin-dependent kinase 22.7.11.220.458
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.458
4i22IREEpidermal growth factor receptor2.7.10.10.458
4o0sADNAurora kinase A2.7.11.10.458
2csnCKICasein kinase I homolog 12.7.11.10.457
2etm7PYFocal adhesion kinase 12.7.10.20.457
2q6cHR13-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.340.457
3at3ATKCasein kinase II subunit alpha2.7.11.10.457
3c1xCKKHepatocyte growth factor receptor2.7.10.10.457
3cd57HI3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.340.457
3mtlFEFCyclin-dependent kinase 162.7.11.220.457
3qd33Q53-phosphoinositide-dependent protein kinase 12.7.11.10.457
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
4ge40KEKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.457
4gu610NFocal adhesion kinase 12.7.10.20.457
4jr7GNPCasein kinase II subunit alpha2.7.11.10.457
1bygSTUTyrosine-protein kinase CSK/0.456
1j7kATPHolliday junction ATP-dependent DNA helicase RuvB/0.456
1jpaANPEphrin type-B receptor 22.7.10.10.456
1kzjCB3Thymidylate synthase/0.456
2acxANPG protein-coupled receptor kinase 62.7.11.160.456
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.456
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.456
3bhtMFRCyclin-dependent kinase 22.7.11.220.456
3o0iP54Heat shock protein HSP 90-alpha/0.456
3tdvGDPGentamicin resistance protein/0.456
3w0sANPHygromycin-B 4-O-kinase2.7.1.1630.456
4bchT7ZCyclin-dependent kinase 92.7.11.220.456
4f650S9Fibroblast growth factor receptor 1/0.456
4h3ySAHtRNA (guanine-N(1)-)-methyltransferase/0.456
4othDRNSerine/threonine-protein kinase N1/0.456
4wboANWRhodopsin kinase/0.456
1bwsNDPGDP-L-fucose synthase/0.455
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.455
1tezFADDeoxyribodipyrimidine photo-lyase4.1.99.30.455
2j0k4STFocal adhesion kinase 12.7.10.20.455
3d8vUD1Bifunctional protein GlmU/0.455
3kc3MK2MAP kinase-activated protein kinase 22.7.11.10.455
3vf2ADPnebramycin 5' synthase6.1.2.20.455
4ez50RSCyclin-dependent kinase 62.7.11.220.455
4hyu1BKMitogen-activated protein kinase 82.7.11.240.455
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.455
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.455
4nk92K5Fibroblast growth factor receptor 1/0.455
4o701QKBromodomain-containing protein 4/0.455
4xq9NADHomospermidine synthase2.5.1.440.455
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.454
2chlDKICasein kinase I isoform gamma-32.7.11.10.454
2eufLQQCyclin-dependent kinase 62.7.11.220.454
2iw6QQ2Cyclin-dependent kinase 22.7.11.220.454
2pe039Z3-phosphoinositide-dependent protein kinase 12.7.11.10.454
2w1gL0GAurora kinase A2.7.11.10.454
2zbaZBATrichothecene 3-O-acetyltransferase/0.454
3bhh5CPCalcium/calmodulin-dependent protein kinase type II subunit beta2.7.11.170.454
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.454
4f081RSTyrosine-protein kinase JAK2/0.454
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.454
4fx360KCyclin-dependent kinase 22.7.11.220.454
5f0a1FBcGMP-dependent protein kinase, putative/0.454
1hk5T44Serum albumin/0.453
1j39UPGDNA beta-glucosyltransferase/0.453
1nzfUPGDNA beta-glucosyltransferase/0.453
1pjkANPCasein kinase II subunit alpha2.7.11.10.453
1ppjANYCytochrome b/0.453
1vyw292Cyclin-dependent kinase 22.7.11.220.453
2aazCB3Thymidylate synthase2.1.1.450.453
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.453
2oj9BMIInsulin-like growth factor 1 receptor2.7.10.10.453
2wpa889Cyclin-dependent kinase 22.7.11.220.453
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.453
3nizADPCdc2-like CDK2/CDC28 like protein kinase/0.453
3ormAGSSerine/threonine protein kinase/0.453
3rk909ZCyclin-dependent kinase 22.7.11.220.453
4bdhWVISerine/threonine-protein kinase Chk22.7.11.10.453
5itzLOCTubulin beta-2B chain/0.453
1csnATPCasein kinase I homolog 12.7.11.10.452
1t0lNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.452
1vjy460TGF-beta receptor type-12.7.11.300.452
1xddAAYIntegrin alpha-L/0.452
1yw2PGJMitogen-activated protein kinase 14/0.452
2eq7NADDihydrolipoyl dehydrogenase/0.452
2ittAEEEpidermal growth factor receptor2.7.10.10.452
2uzeC95Cyclin-dependent kinase 22.7.11.220.452
2wxvWXVCyclin-dependent kinase 22.7.11.220.452
3a60STURibosomal protein S6 kinase beta-12.7.11.10.452
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.452
3k5uPFQAurora kinase A2.7.11.10.452
3nuuJOZ3-phosphoinositide-dependent protein kinase 12.7.11.10.452
3pmy41LEndothiapepsin3.4.23.220.452
4az3S35Lysosomal protective protein3.4.16.50.452
4cax646Glycylpeptide N-tetradecanoyltransferase2.3.1.970.452
4gk2L66Ephrin type-A receptor 32.7.10.10.452
4hgs15GCasein kinase I isoform gamma-32.7.11.10.452
4i3wNADAldehyde dehydrogenase (NAD+)/0.452
4j6dTESCytochrome P450 monooxygenase/0.452
4mvfSTUCalcium-dependent protein kinase 22.7.11.10.452
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.452
1fdtESTEstradiol 17-beta-dehydrogenase 11.1.1.620.451
1gqtACPRibokinase/0.451
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.451
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.451
2qg2A91Heat shock protein HSP 90-alpha/0.451
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.451
3kn5ANPRibosomal protein S6 kinase alpha-52.7.11.10.451
3nr4PYVAbscisic acid receptor PYL2/0.451
3p6oETGCamphor 5-monooxygenase1.14.15.10.451
4brxKGWFocal adhesion kinase 12.7.10.20.451
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.451
1nzdUPGDNA beta-glucosyltransferase/0.450
1uymPU3Heat shock protein HSP 90-beta/0.450
1vruAAPGag-Pol polyprotein2.7.7.490.450
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.450
3a7hATPSerine/threonine-protein kinase 242.7.11.10.450
3fhxPXLPyridoxal kinase2.7.1.350.450
3fln3FNMitogen-activated protein kinase 14/0.450
3hx4ANPCalmodulin-domain protein kinase 1/0.450
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.450
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.450
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.450
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.450
4gub0Y4Casein kinase II subunit alpha2.7.11.10.450
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.450
4kbk1QGCasein kinase I isoform delta2.7.11.10.450
4kzoNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.450
4o2bLOCTubulin beta-2B chain/0.450
4u9zCOAAlpha-tubulin N-acetyltransferase 1/0.450
5av3KMPDeath-associated protein kinase 12.7.11.10.450
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.449
1oi9N20Cyclin-dependent kinase 22.7.11.220.449
1uy7PU4Heat shock protein HSP 90-alpha/0.449
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.449
2biyATP3-phosphoinositide-dependent protein kinase 12.7.11.10.449
2c3qGTXGlutathione S-transferase theta-12.5.1.180.449
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.449
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.449
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.449
3inxJZCHeat shock protein HSP 90-alpha/0.449
3le62BZCyclin-dependent kinase 22.7.11.220.449
3nww3NWMitogen-activated protein kinase 14/0.449
3p6pA6BCamphor 5-monooxygenase1.14.15.10.449
3pgqGY3Acetyl-CoA carboxylase/0.449
3s1dZIRCytokinin dehydrogenase 11.5.99.120.449
3vewADPnebramycin 5' synthase6.1.2.20.449
3wmxNADNAD dependent epimerase/dehydratase/0.449
4aicNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.449
4g160VMCasein kinase I isoform gamma-32.7.11.10.449
4jx1CAMCamphor 5-monooxygenase1.14.15.10.449
4nh82LCHeat shock protein HSP 90-alpha/0.449
4o4fATPKinase/0.449
4oacADPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.449
4qmwKS1Serine/threonine-protein kinase 242.7.11.10.449
5dgzL20Serine/threonine-protein kinase pim-12.7.11.10.449
3emlZMAAdenosine receptor A2a/0.449
1fvt106Cyclin-dependent kinase 22.7.11.220.448
1gij2PUCyclin-dependent kinase 22.7.11.220.448
2bl9CP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.448
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.448
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.448
2dwbANPAurora kinase A2.7.11.10.448
2e9p77ASerine/threonine-protein kinase Chk12.7.11.10.448
2huvSAHDiphthine synthase/0.448
2j0j4STFocal adhesion kinase 12.7.10.20.448
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.448
2ydjYDJSerine/threonine-protein kinase Chk12.7.11.10.448
3bhy7CPDeath-associated protein kinase 3/0.448
3ituIBMcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.448
3mqe416Prostaglandin G/H synthase 21.14.99.10.448
3nd1SAHPrecorrin-6A synthase (Deacetylating)/0.448
3oroAGSSerine/threonine protein kinase/0.448
3ox4NADAlcohol dehydrogenase 21.1.1.10.448
3q9xEMOCasein kinase II subunit alpha2.7.11.10.448
3r83Z14Cyclin-dependent kinase 22.7.11.220.448
3s2pPMUCyclin-dependent kinase 22.7.11.220.448
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.448
3t8oATPRhodopsin kinase/0.448
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.448
4hgl0YOCasein kinase I isoform gamma-32.7.11.10.448
4kb81QNCasein kinase I isoform delta2.7.11.10.448
4nmbFADBifunctional protein PutA/0.448
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.448
4rqvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.448
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.448
5dqrFAD7-hydroxymethyl chlorophyll a reductase, chloroplastic1.17.7.20.448
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.447
1phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.447
1uu3LY43-phosphoinositide-dependent protein kinase 12.7.11.10.447
1vrwNAIEnoyl-ACP reductase/0.447
2e8hSAHDiphthine synthase/0.447
3cy3JN5Serine/threonine-protein kinase pim-12.7.11.10.447
3drcMTXDihydrofolate reductase1.5.1.30.447
3dxjNE6DNA-directed RNA polymerase subunit beta/0.447
3dxjNE6DNA-directed RNA polymerase subunit beta'/0.447
3lpbNVBTyrosine-protein kinase JAK2/0.447
3zewSTUEphrin type-B receptor 42.7.10.10.447
3zuyTCHTransporter/0.447
4e4m0NHTyrosine-protein kinase JAK2/0.447
4eos1ROCyclin-dependent kinase 22.7.11.220.447
4erwSTUCyclin-dependent kinase 22.7.11.220.447
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.447
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.447
4n6z2HWSerine/threonine-protein kinase pim-12.7.11.10.447
5fd8A5APutative carboxypeptidase yocD/0.447
1e7aPFLSerum albumin/0.446
1wvySTUDeath-associated protein kinase 12.7.11.10.446
1y91CT9Cyclin-dependent kinase 22.7.11.220.446
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.446
2itnANPEpidermal growth factor receptor2.7.10.10.446
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.446
2pvnP63Casein kinase II subunit alpha2.7.11.10.446
2wmvZYVSerine/threonine-protein kinase Chk12.7.11.10.446
3bgpVX1Serine/threonine-protein kinase pim-12.7.11.10.446
3mvl38PMitogen-activated protein kinase 14/0.446
3s7a684Dihydrofolate reductase1.5.1.30.446
3u4uLNHCasein kinase II subunit alpha2.7.11.10.446
3vs5VSGTyrosine-protein kinase HCK2.7.10.20.446
3zep1NXTyrosine-protein kinase JAK32.7.10.20.446
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.446
4dfrMTXDihydrofolate reductase1.5.1.30.446
4hvi19STyrosine-protein kinase JAK32.7.10.20.446
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.446
4wh3ATPN-acetylhexosamine 1-kinase2.7.1.1620.446
1eh4IC1Casein kinase I homolog 12.7.11.10.445
1mq4ADPAurora kinase A2.7.11.10.445
1py5PY1TGF-beta receptor type-12.7.11.300.445
1v9aSAHUncharacterized protein/0.445
2cchATPCyclin-dependent kinase 22.7.11.220.445
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.445
2ojj82AMitogen-activated protein kinase 12.7.11.240.445
2p2xSAHDiphthine synthase/0.445
2uw4L15cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
3gobHXXDdmC/0.445
3l8p0CEAngiopoietin-1 receptor2.7.10.10.445
3oibFDAPutative acyl-CoA dehydrogenase/0.445
3pxkPXKFocal adhesion kinase 12.7.10.20.445
3qgtCP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.445
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.445
4ccbOFGALK tyrosine kinase receptor2.7.10.10.445
4hnf16WCasein kinase I isoform delta2.7.11.10.445
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.445
1drhNAPDihydrofolate reductase1.5.1.30.444
1e8zSTUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
1f28F89Thymidylate synthase2.1.1.450.444
1h1q2A6Cyclin-dependent kinase 22.7.11.220.444
1tqmANPRIO-type serine/threonine-protein kinase Rio22.7.11.10.444
1yi4ADNSerine/threonine-protein kinase pim-12.7.11.10.444
2bfyH1NAurora kinase B-A2.7.11.10.444
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.444
2emuSAHDiphthine synthase/0.444
2jkoBIJFocal adhesion kinase 12.7.10.20.444
2owkSAHDiphthine synthase/0.444
2w05FRTCyclin-dependent kinase 22.7.11.220.444
2w17I19Cyclin-dependent kinase 22.7.11.220.444
2wihP48Cyclin-dependent kinase 22.7.11.220.444
3g5qFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.444
3l08ZIGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
4b8mVX6Aurora kinase B-A2.7.11.10.444
4e5yNDPGDP-L-fucose synthase1.1.1.2710.444
4eol1ROCyclin-dependent kinase 22.7.11.220.444
4hvb19PPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
4ib4ERM5-hydroxytryptamine receptor 2B/0.444
4ji91M3Tyrosine-protein kinase JAK2/0.444
4ktc1X3Genome polyprotein3.4.21.980.444
4rupH97Vitamin D3 receptor A/0.444
5drdATPAurora kinase A2.7.11.10.444
1pkdUCNCyclin-dependent kinase 22.7.11.220.443
1qnfFADDeoxyribodipyrimidine photo-lyase4.1.99.30.443
1rw8580TGF-beta receptor type-12.7.11.300.443
1zarADPRIO-type serine/threonine-protein kinase Rio22.7.11.10.443
2b365PPEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.443
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.443
2yee2ECHeat shock protein HSP 90-alpha/0.443
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.443
3cquCQURAC-alpha serine/threonine-protein kinase2.7.11.10.443
3p67FMNPentaerythritol tetranitrate reductase/0.443
3v0p4GWHisto-blood group ABO system transferase/0.443
4fkv61KCyclin-dependent kinase 22.7.11.220.443
4gii0X6Non-receptor tyrosine-protein kinase TYK22.7.10.20.443
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4nm9FADBifunctional protein PutA/0.443
4qmnDB8Serine/threonine-protein kinase 242.7.11.10.443
4z5wILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.443
1diuBDMDihydrofolate reductase1.5.1.30.442
1e3eNAIAlcohol dehydrogenase 41.1.1.10.442
1k6cMK1Gag-Pol polyprotein3.4.23.160.442
1ma0NADAlcohol dehydrogenase class-31.1.1.10.442
1nooCAHCamphor 5-monooxygenase1.14.15.10.442
1oirHDYCyclin-dependent kinase 22.7.11.220.442
1q4t4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.442
1uy8PU5Heat shock protein HSP 90-alpha/0.442
2ad5ADPCTP synthase/0.442
2b52D42Cyclin-dependent kinase 22.7.11.220.442
2b7aIZATyrosine-protein kinase JAK2/0.442
2btsU32Cyclin-dependent kinase 22.7.11.220.442
2c0iL1GTyrosine-protein kinase HCK2.7.10.20.442
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
2duv371Cyclin-dependent kinase 22.7.11.220.442
2hqmFADGlutathione reductase1.8.1.70.442
2j3nFADThioredoxin reductase 1, cytoplasmic1.8.1.90.442
2pmdGNPTranslation initiation factor 2 subunit gamma/0.442
2pvlP55Casein kinase II subunit alpha2.7.11.10.442
2uzdC85Cyclin-dependent kinase 22.7.11.220.442
2yac937Serine/threonine-protein kinase PLK12.7.11.210.442
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.442
2zoq5IDMitogen-activated protein kinase 32.7.11.240.442
3amaSKEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.442
3hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.442
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.442
3plsANPMacrophage-stimulating protein receptor2.7.10.10.442
3sa27DRDihydrofolate reductase/0.442
3tnlNADShikimate dehydrogenase (NADP(+))/0.442
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
4aqc88ATyrosine-protein kinase JAK2/0.442
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.442
4deaNHIAurora kinase A2.7.11.10.442
4fkr45KCyclin-dependent kinase 22.7.11.220.442
4ia2BIVVitamin D3 receptor A/0.442
4n57ADPAPH(2'')-Id/0.442
4o4eATPKinase/0.442
4v12POGMaoC like domain protein/0.442
5akk1P8Bifunctional epoxide hydrolase 23.1.3.760.442
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.441
1uu7BI23-phosphoinositide-dependent protein kinase 12.7.11.10.441
1wn3HXCPhenylacetic acid degradation protein PaaI/0.441
2c5yMTWCyclin-dependent kinase 22.7.11.220.441
2e07SAHDiphthine synthase/0.441
2fgjATPAlpha-hemolysin translocation ATP-binding protein HlyB/0.441
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.441
2vcmM11Isopenicillin N synthase1.21.3.10.441
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.441
3c4eC4ESerine/threonine-protein kinase pim-12.7.11.10.441
3gggNADPrephenate dehydrogenase/0.441
3nbvANPKetohexokinase/0.441
3nga3NGCasein kinase II subunit alpha2.7.11.10.441
3oafOAGDihydrofolate reductase1.5.1.30.441
3oquA8SAbscisic acid receptor PYL9/0.441
3ox1695Ribosyldihydronicotinamide dehydrogenase [quinone]/0.441
3poz03PEpidermal growth factor receptor2.7.10.10.441
3tqhNDPQuinone oxidoreductase/0.441
3w0nANPHygromycin-B 4-O-kinase2.7.1.1630.441
3zc3NAPFerredoxin--NADP reductase1.18.1.20.441
4bgiI4IEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
4bqh9VUUDP-N-acetylglucosamine pyrophosphorylase, putative/0.441
4d4sBI9Focal adhesion kinase 12.7.10.20.441
4h9506UDihydrofolate reductase1.5.1.30.441
4jb1FADUDP-N-acetylenolpyruvoylglucosamine reductase/0.441
4l8u9AZSerum albumin/0.441
4l8vNAPInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase1.1.1.180.441
4ryvZEAProtein LlR18A/0.441
4wx1FDAUDP-galactopyranose mutase/0.441
5dt4ATPAurora kinase A2.7.11.10.441
1bxqPP8Penicillopepsin-13.4.23.200.440
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.440
1dfoFFOSerine hydroxymethyltransferase2.1.2.10.440
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.440
1mvsDTMDihydrofolate reductase1.5.1.30.440
1rbqKEUTrifunctional purine biosynthetic protein adenosine-32.1.2.20.440
1uy6PU3Heat shock protein HSP 90-alpha/0.440
1v0pPVBCell division control protein 2 homolog2.7.11.220.440
1xjdSTUProtein kinase C theta type2.7.11.130.440
1zaoATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.440
2fumMIXSerine/threonine-protein kinase PknB2.7.11.10.440
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.440
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.440
2qocANPEphrin type-A receptor 32.7.10.10.440
2wouZZFTGF-beta receptor type-12.7.11.300.440
2ww4ADP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase2.7.1.1480.440
2z97CAMCamphor 5-monooxygenase1.14.15.10.440
3cylVITBasic phospholipase A2 homolog piratoxin-2/0.440
3ibqATPPyridoxal kinase/0.440
3l1sZ92Glycogen synthase kinase-3 beta2.7.11.260.440
3lu8IQXSerum albumin/0.440
3p79P79Mitogen-activated protein kinase 14/0.440
3qlrNDPDihydrofolate reductase1.5.1.30.440
3qqkX02Cyclin-dependent kinase 22.7.11.220.440
3tea4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.440
3uzp0CKCasein kinase I isoform delta2.7.11.10.440
3vs6VSHTyrosine-protein kinase HCK2.7.10.20.440
3vt5YI2Vitamin D3 receptor/0.440
4alhA9PBromodomain-containing protein 2/0.440
4bcqTJFCyclin-dependent kinase 22.7.11.220.440
4cvmANPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.440
4cztCPSCBL-interacting serine/threonine-protein kinase 232.7.11.10.440
4fks46KCyclin-dependent kinase 22.7.11.220.440
4fr0SAMArsenic methyltransferase/0.440
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.440
4fuyEK2Mitogen-activated protein kinase 12.7.11.240.440
4igeCHJEnoyl-acyl carrier reductase/0.440
4ix5ANPUncharacterized protein/0.440
4j1rI5RGlycogen synthase kinase-3 beta2.7.11.260.440
4r20AERCytochrome P450 family 17 polypeptide 2/0.440
4y93746Tyrosine-protein kinase/0.440
5cvhADPCasein kinase II subunit alpha2.7.11.10.440
5ks72BACarnitine transport ATP-binding protein OpuCA3.6.3.320.440