Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2pb4SAHDiphthine synthase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2pb4SAHDiphthine synthase/1.000
2ek7SAHDiphthine synthase/0.857
2en5SAHDiphthine synthase/0.842
2e8qSAHDiphthine synthase/0.838
2emuSAHDiphthine synthase/0.838
2dxvSAHDiphthine synthase/0.819
2dxwSAHDiphthine synthase/0.817
2e16SAHDiphthine synthase/0.817
2e8sSAHDiphthine synthase/0.814
2pcmSAHDiphthine synthase/0.809
2emrSAHDiphthine synthase/0.807
2dsgSAHDiphthine synthase/0.804
2eglSAHDiphthine synthase/0.791
2pb6SAHDiphthine synthase/0.788
2p6dSAHDiphthine synthase/0.787
2eh5SAHDiphthine synthase/0.785
2dv4SAHDiphthine synthase/0.780
2huxSAHDiphthine synthase/0.774
2eniSAHDiphthine synthase/0.769
2el0SAHDiphthine synthase/0.767
2dv7SAHDiphthine synthase/0.765
1wngSAHDiphthine synthase/0.757
2p6kSAHDiphthine synthase/0.753
2ed5SAHDiphthine synthase/0.749
2ehlSAHDiphthine synthase/0.745
2dv3SAHDiphthine synthase/0.741
2ejkSAHDiphthine synthase/0.741
2pchSAHDiphthine synthase/0.735
2egsSAHDiphthine synthase/0.722
2ekaSAHDiphthine synthase/0.715
2p6lSAHDiphthine synthase/0.705
2p2xSAHDiphthine synthase/0.698
2ek4SAHDiphthine synthase/0.696
2pcgSAHDiphthine synthase/0.696
2pcaSAHDiphthine synthase/0.691
2dekSAHDiphthine synthase/0.690
1vceSAHDiphthine synthase/0.687
2e4nSAHDiphthine synthase/0.687
2eh2SAHDiphthine synthase/0.687
2owkSAHDiphthine synthase/0.687
2owvSAHDiphthine synthase/0.686
2e7rSAHDiphthine synthase/0.672
2egbSAHDiphthine synthase/0.672
2e8hSAHDiphthine synthase/0.671
2p5cSAHDiphthine synthase/0.669
2eldSAHDiphthine synthase/0.668
2eh4SAHDiphthine synthase/0.667
2eleSAHDiphthine synthase/0.667
2dsiSAHDiphthine synthase/0.666
2p5fSAHDiphthine synthase/0.663
2ek2SAHDiphthine synthase/0.662
2el3SAHDiphthine synthase/0.658
2hr8SAHDiphthine synthase/0.657
2p9dSAHDiphthine synthase/0.653
2huvSAHDiphthine synthase/0.647
2ejjSAHDiphthine synthase/0.645
2e8rSAHDiphthine synthase/0.644
2e08SAHDiphthine synthase/0.641
2dxxSAHDiphthine synthase/0.640
2owgSAHDiphthine synthase/0.636
2eeqSAHDiphthine synthase/0.632
2pciSAHDiphthine synthase/0.632
2z6rSAHDiphthine synthase/0.631
2e17SAHDiphthine synthase/0.623
2hutSAHDiphthine synthase/0.619
2owuSAHDiphthine synthase/0.616
2pb5SAHDiphthine synthase/0.616
2e07SAHDiphthine synthase/0.611
2pckSAHDiphthine synthase/0.610
2p6iSAHDiphthine synthase/0.600
2dshSAHDiphthine synthase/0.597
2huqSAHDiphthine synthase/0.594
2dv5SAHDiphthine synthase/0.588
2owfSAHDiphthine synthase/0.586
2ejzSAHDiphthine synthase/0.578
2e15SAHDiphthine synthase/0.558
2ek3SAHDiphthine synthase/0.553
2ed3SAHDiphthine synthase/0.545
1xe55FEPlasmepsin-23.4.23.390.524
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.507
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.507
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.506
3b70NAPEnoyl reductase LovC10.499
2qbuSAHPrecorrin-2 methyltransferase/0.498
3djjFADGlutathione reductase, mitochondrial1.8.1.70.498
4g7gVFVLanosterol 14-alpha-demethylase/0.497
3gw9VNILanosterol 14-alpha-demethylase/0.495
2ztvNADD(-)-3-hydroxybutyrate dehydrogenase/0.494
4pl0ANPMicrocin-J25 export ATP-binding/permease protein McjD/0.493
2x06NADL-sulfolactate dehydrogenase/0.489
3a3gDLZLumazine protein/0.489
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.489
3uoyFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.488
3up5FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.488
4ipw1G7Mycocyclosin synthase1.14.21.90.488
3uozFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.487
2qs3UBEGlutamate receptor ionotropic, kainate 1/0.486
1lbcCYZGlutamate receptor 2/0.485
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.485
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.484
2rbeNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.484
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.483
3vqsJT1Genome polyprotein/0.483
4a8v2ANMajor pollen allergen Bet v 1-J/0.483
4bc7FADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.483
4jnkZHKL-lactate dehydrogenase A chain1.1.1.270.483
2p5uNADUDP-glucose 4-epimerase/0.482
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.482
3gqvNAPEnoyl reductase LovC10.482
1dr3TAPDihydrofolate reductase1.5.1.30.481
1h8hATPATP synthase subunit alpha, mitochondrial/0.481
1h8hATPATP synthase subunit beta, mitochondrial3.6.3.140.481
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.481
1xs7MMIBeta-secretase 13.4.23.460.481
2hunNAD336aa long hypothetical dTDP-glucose 4,6-dehydratase/0.481
2pswCOAN-alpha-acetyltransferase 50/0.481
4i6aHMG3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.481
5eb5FAD(R)-mandelonitrile lyase 14.1.2.100.481
1bxoPP7Penicillopepsin-13.4.23.200.480
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.480
4q71FADBifunctional protein PutA/0.480
5dp2NAPCurF/0.480
1nzdUPGDNA beta-glucosyltransferase/0.479
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.479
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.479
3ig6438Urokinase-type plasminogen activator3.4.21.730.479
1g1aNADdTDP-glucose 4,6-dehydratase/0.478
1g63FMNEpidermin decarboxylase4.1.10.478
2a94AP0L-lactate dehydrogenase1.1.1.270.478
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.478
4bfzZVZPantothenate kinase2.7.1.330.478
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.478
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.478
3rufNADUDP-N-acetylglucosamine 4-epimerase/0.477
4j0v1H7Beta-secretase 13.4.23.460.477
2iyfERYOleandomycin glycosyltransferase2.4.10.476
2q5g1FAPeroxisome proliferator-activated receptor delta/0.476
3te5NAI5'-AMP-activated protein kinase subunit gamma/0.476
1e1qANPATP synthase subunit alpha, mitochondrial/0.475
1e1qANPATP synthase subunit beta, mitochondrial3.6.3.140.475
1w6hTITPlasmepsin-23.4.23.390.475
3d4pNADL-lactate dehydrogenase 11.1.1.270.475
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.475
1bk0ACVIsopenicillin N synthase1.21.3.10.474
1dirNADDihydropteridine reductase1.5.1.340.474
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.474
2dftADPShikimate kinase2.7.1.710.474
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.474
2y1tDUDSPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS3.6.1.230.473
4wudANPDNA gyrase subunit B/0.473
2gjlFMNNitronate monooxygenase1.13.12.160.472
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.472
3d91REMRenin3.4.23.150.472
1qiqACCIsopenicillin N synthase1.21.3.10.471
3hl0NADMaleylacetate reductase/0.471
3iqiASN_GLU_ASN_ILECysteine synthase2.5.1.470.471
3lqfNADGalactitol dehydrogenase/0.471
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.471
4ips1G4Mycocyclosin synthase1.14.21.90.471
4oqyNDP(S)-imine reductase/0.471
1xe65FPPlasmepsin-23.4.23.390.470
3v0p4GWHisto-blood group ABO system transferase/0.470
4egbNADdTDP-glucose 4,6-dehydratase/0.470
4ejmNAPPutative zinc-binding dehydrogenase/0.470
4iqlFMNEnoyl-(Acyl-carrier-protein) reductase II/0.470
1bwsNDPGDP-L-fucose synthase/0.469
1f8fNADBenzyl alcohol dehydrogenase/0.469
1f8wFADNADH peroxidase1.11.1.10.469
1kbo340NAD(P)H dehydrogenase [quinone] 11.6.5.20.469
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.469
1ur5NADMalate dehydrogenase/0.469
2ahrNAPPyrroline-5-carboxylate reductase/0.469
2zvbSAHPrecorrin-3 C17-methyltransferase/0.469
3ijoB4DGlutamate receptor 2/0.469
4m83ERYOleandomycin glycosyltransferase2.4.10.469
1ib0NADNADH-cytochrome b5 reductase 31.6.2.20.468
1mjaCOAHistone acetyltransferase ESA1/0.468
1mjbACOHistone acetyltransferase ESA1/0.468
1x1aSAMC-20 methyltransferase/0.468
2g1s4IGRenin3.4.23.150.468
2xhd7T9Glutamate receptor 2/0.468
4dbzNDPPutative ketoacyl reductase1.3.10.468
4r7uUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.468
1hb3SCVIsopenicillin N synthase1.21.3.10.467
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.467
1me6IVSPlasmepsin-23.4.23.390.467
2ojtUBAGlutamate receptor ionotropic, kainate 1/0.467
4g3jVNTLanosterol 14-alpha-demethylase/0.467
4nd3NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.467
5adhAPRAlcohol dehydrogenase E chain1.1.1.10.467
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.466
1u8vFAD4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase/0.466
2fxv5GPXanthine phosphoribosyltransferase2.4.2.220.466
2g8yNADHydroxycarboxylate dehydrogenase B/0.466
2wo7ASVIsopenicillin N synthase1.21.3.10.466
2y3sTIRTamL/0.466
3ndcSAHPrecorrin-4 C(11)-methyltransferase2.1.1.1330.466
3slkNDPPolyketide synthase extender module 2/0.466
3zoiM2WIsopenicillin N synthase1.21.3.10.466
1fy7COAHistone acetyltransferase ESA1/0.465
1hb1OCVIsopenicillin N synthase1.21.3.10.465
1hdrNADDihydropteridine reductase1.5.1.340.465
1tqf32PBeta-secretase 13.4.23.460.465
2he5NDPAldo-keto reductase family 1 member C211.1.10.465
3lpjZ75Beta-secretase 13.4.23.460.465
3nutSAHPrecorrin-3 methylase/0.465
4q0kGA3Phytohormone-binding protein/0.465
1lf3EH5Plasmepsin-23.4.23.390.464
1rneC60Renin3.4.23.150.464
1x1dSAHC-20 methyltransferase/0.464
2bn4FMNNADPH--cytochrome P450 reductase/0.464
2ifaFMNUncharacterized protein/0.464
2iviACWIsopenicillin N synthase1.21.3.10.464
2vwqNAPGlucose 1-dehydrogenase/0.464
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.464
3lpiZ74Beta-secretase 13.4.23.460.464
1hygNAPL-2-hydroxycarboxylate dehydrogenase (NAD(P)(+))/0.463
1nuqNXXNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.463
1q0zAKAAclacinomycin methylesterase RdmC3.1.1.950.463
1udaUFGUDP-glucose 4-epimerase5.1.3.20.463
2bu9HFVIsopenicillin N synthase1.21.3.10.463
2rlcCHDCholoylglycine hydrolase3.5.1.240.463
4a862ANMajor pollen allergen Bet v 1-A/0.463
4djy0KRBeta-secretase 13.4.23.460.463
1nuuNADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.462
1pjcNADAlanine dehydrogenase/0.462
3jzdNADMaleylacetate reductase/0.462
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.462
4kb9G79Protease/0.462
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.462
5hwsNAP2-dehydropantoate 2-reductase/0.462
1bmfANPATP synthase subunit alpha, mitochondrial/0.461
1bmfANPATP synthase subunit beta, mitochondrial3.6.3.140.461
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.461
1ptjNAPNAD(P) transhydrogenase subunit beta1.6.1.20.461
1t2cNAIL-lactate dehydrogenase1.1.1.270.461
1v9aSAHUncharacterized protein/0.461
1x1cSAHC-20 methyltransferase/0.461
2gv8NDPThiol-specific monooxygenase1.14.130.461
3d8bADPFidgetin-like protein 13.6.40.461
3w8eNAD3-hydroxybutyrate dehydrogenase/0.461
4i1iNADMalate dehydrogenase/0.461
4r21STRCytochrome P450 family 17 polypeptide 2/0.461
1h74ADPHomoserine kinase2.7.1.390.460
1vikBAYGag-Pol polyprotein/0.460
1xddAAYIntegrin alpha-L/0.460
2pj4414Carboxypeptidase B/0.460
3lpkZ76Beta-secretase 13.4.23.460.460
3q43D66M1 family aminopeptidase3.4.110.460
3zkyWT4Isopenicillin N synthase1.21.3.10.460
4bbyFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.460
4eakATP5'-AMP-activated protein kinase subunit gamma-1/0.460
1bxqPP8Penicillopepsin-13.4.23.200.459
1kp3ATPArgininosuccinate synthase6.3.4.50.459
1obnASVIsopenicillin N synthase1.21.3.10.459
2oapANPType II secretion system protein (GspE-2)/0.459
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.459
4ef8FMNDihydroorotate dehydrogenase (fumarate)/0.459
5a0yCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.459
5a0yCOMMethyl-coenzyme M reductase I subunit beta2.8.4.10.459
1dxoFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.458
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.458
1ohhANPATP synthase subunit alpha, mitochondrial/0.458
1ohhANPATP synthase subunit beta, mitochondrial3.6.3.140.458
1pd9CO4Dihydrofolate reductase1.5.1.30.458
1psa0ZLPepsin A3.4.23.10.458
2hrcCHDFerrochelatase, mitochondrial4.99.1.10.458
2q4bNAPUncharacterized protein At5g02240/0.458
2z54AB1Gag-Pol polyprotein3.4.23.160.458
3cid318Beta-secretase 13.4.23.460.458
3wagTYDGlycosyltransferase/0.458
4a83DXCMajor pollen allergen Bet v 1-A/0.458
4nbwNADShort-chain dehydrogenase/reductase SDR/0.458
5af7FADAcyl-CoA dehydrogenase/0.458
5ao1DG3Deoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.458
5d3qGDPDynamin-13.6.5.50.458
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.457
1y4lSVRBasic phospholipase A2 homolog 2/0.457
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.457
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.457
2xlrFADPutative flavin-containing monooxygenase/0.457
2zvcSAHPrecorrin-3 C17-methyltransferase/0.457
3ik6HCZGlutamate receptor 2/0.457
3ixj586Beta-secretase 13.4.23.460.457
3qwbNDPProbable quinone oxidoreductase1.6.5.50.457
3u33FADPutative acyl-CoA dehydrogenase AidB1.3.990.457
4bfxZVXPantothenate kinase2.7.1.330.457
5c1mCLRMu-type opioid receptor/0.457
1e5qNDPSaccharopine dehydrogenase [NADP(+), L-glutamate-forming]1.5.1.100.456
1nhhANPDNA mismatch repair protein MutL/0.456
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.456
1zioAP5Adenylate kinase/0.456
2c20NADUDP-glucose 4-epimerase/0.456
2gz7D3FOrf1a polyprotein/0.456
2p83MR0Beta-secretase 13.4.23.460.456
2vbdV10Isopenicillin N synthase1.21.3.10.456
2y4gTIRTamL/0.456
3e8xNAPBH1520 protein/0.456
3ieuGDPGTPase Era/0.456
3p2eSAH16S rRNA (adenine(1408)-N(1))-methyltransferase2.1.1.1800.456
3widNAPGlucose 1-dehydrogenase/0.456
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.456
4h3f10OBeta-secretase 13.4.23.460.456
4n5nNAPAcetoacetyl-CoA reductase1.1.1.360.456
4wucANPDNA gyrase subunit B/0.456
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.455
1yqzCOACoenzyme A disulfide reductase/0.455
2g226IGRenin3.4.23.150.455
2v7qATPATP synthase subunit alpha, mitochondrial/0.455
2v7qATPATP synthase subunit beta, mitochondrial3.6.3.140.455
2zbaZBATrichothecene 3-O-acetyltransferase/0.455
3mpjFADGlutaryl-CoA dehydrogenase1.3.99.320.455
3wv9FEGHmd co-occurring protein HcgE/0.455
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.455
5irnADPNucleotide binding oligomerization domain containing 2/0.455
5jscFADPutative acyl-CoA dehydrogenase/0.455
1cs4FOKAdenylate cyclase type 2/0.454
1cs4FOKAdenylate cyclase type 5/0.454
1dhrNADDihydropteridine reductase1.5.1.340.454
1t88CAMCamphor 5-monooxygenase1.14.15.10.454
1xvaSAMGlycine N-methyltransferase2.1.1.200.454
2givACOHistone acetyltransferase KAT8/0.454
2il2LIXRenin3.4.23.150.454
2q1wNADPutative nucleotide sugar epimerase/ dehydratase/0.454
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.454
2wecPP5Penicillopepsin-13.4.23.200.454
2wedPP6Penicillopepsin-13.4.23.200.454
2ylzFADPhenylacetone monooxygenase1.14.13.920.454
3c1y2BADNA integrity scanning protein DisA/0.454
3tjzGNPADP-ribosylation factor 1/0.454
4dh60KNBeta-secretase 13.4.23.460.454
4f5yC2EStimulator of interferon genes protein/0.454
4i8zG08Gag-Pol polyprotein3.4.23.160.454
4xr9NADCalS8/0.454
1bil0IURenin3.4.23.150.453
1jedADPSulfate adenylyltransferase/0.453
1lf2R37Plasmepsin-23.4.23.390.453
1orrNADCDP-paratose 2-epimerase/0.453
2jj2ANPATP synthase subunit beta, mitochondrial3.6.3.140.453
2rcyNAPPyrroline-5-carboxylate reductase/0.453
2y60M8FIsopenicillin N synthase1.21.3.10.453
2ztmNADD(-)-3-hydroxybutyrate dehydrogenase/0.453
3clxX22E3 ubiquitin-protein ligase XIAP6.3.20.453
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.453
3ivgFG5Pantothenate synthetase6.3.2.10.453
3uylTYDProbable NDP-rhamnosyltransferase/0.453
4trnNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.453
4yxm2BADNA integrity scanning protein DisA/0.453
1cbfSAHCobalt-precorrin-4 C(11)-methyltransferase2.1.1.2710.452
1ju2FAD(R)-mandelonitrile lyase 24.1.2.100.452
1kkq471Peroxisome proliferator-activated receptor alpha/0.452
1ma0NADAlcohol dehydrogenase class-31.1.1.10.452
1qlhNADAlcohol dehydrogenase E chain1.1.1.10.452
2qs4LY5Glutamate receptor ionotropic, kainate 1/0.452
2xy3DUPSPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS3.6.1.230.452
3cic316Beta-secretase 13.4.23.460.452
3dv3MEKDual specificity mitogen-activated protein kinase kinase 12.7.12.20.452
3ljtLA3A disintegrin and metalloproteinase with thrombospondin motifs 53.4.240.452
3pqbVGPPutative oxidoreductase/0.452
3upkUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.452
4emtC2EStimulator of interferon genes protein/0.452
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.452
4exg916Beta-secretase 13.4.23.460.452
4gsuDWZL,D-transpeptidase 22.3.20.452
1bwlFMNNADPH dehydrogenase 11.6.99.10.451
1ep1FMNDihydroorotate dehydrogenase B (NAD(+)), catalytic subunit1.3.1.140.451
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.451
1zxmANPDNA topoisomerase 2-alpha5.99.1.30.451
2g28TDKPyruvate dehydrogenase E1 component1.2.4.10.451
2rl1UD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.451
2xtnGTPGTPase IMAP family member 2/0.451
3i59N6RCRP-like cAMP-activated global transcriptional regulator/0.451
3in6FMNUncharacterized protein/0.451
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
3oadLPORenin3.4.23.150.451
3p62FMNPentaerythritol tetranitrate reductase/0.451
3qe2FMNNADPH--cytochrome P450 reductase/0.451
3sdkP3NProteasome subunit beta type-53.4.25.10.451
3sdkP3NProteasome subunit beta type-63.4.25.10.451
3uovFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.451
3vn2TLSPeroxisome proliferator-activated receptor gamma/0.451
4ambDUDPutative glycosyl transferase/0.451
4dpy2P0Mevalonate diphosphate decarboxylase/0.451
4f9gC2EStimulator of interferon genes protein/0.451
4ji91M3Tyrosine-protein kinase JAK2/0.451
4kne1CYDihydrofolate reductase1.5.1.30.451
4uugPXGBranched-chain amino acid aminotransferase, putative/0.451
4y3jHICEndothiapepsin3.4.23.220.451
5einNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.451
1gg5E09NAD(P)H dehydrogenase [quinone] 11.6.5.20.450
1hbvGANGag-Pol polyprotein/0.450
1i7gAZ2Peroxisome proliferator-activated receptor alpha/0.450
1juvNDPDihydrofolate reductase1.5.1.30.450
1qy5NECEndoplasmin/0.450
1udyFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.450
2cftPLPPyridoxal phosphate phosphatase/0.450
2fgkATPAlpha-hemolysin translocation ATP-binding protein HlyB/0.450
2gmhFADElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial1.5.5.10.450
2znq401Peroxisome proliferator-activated receptor delta/0.450
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.450
3rudNADUDP-N-acetylglucosamine 4-epimerase/0.450
3uayADNPurine nucleoside phosphorylase DeoD-type/0.450
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.450
4lutDCSAlanine racemase/0.450
5a88ADPRiboflavin biosynthesis protein RibF2.7.1.260.450
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.449
2cmjNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.449
2g1y5IGRenin3.4.23.150.449
2jcvNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.449
2jcxNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.449
2y6fM9FIsopenicillin N synthase1.21.3.10.449
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.449
3b6zCO7Enoyl reductase LovC10.449
3k5c0BIBeta-secretase 13.4.23.460.449
3orfNADDihydropteridine reductase1.5.1.340.449
3zh8C58Protein kinase C iota type2.7.11.130.449
4h3j10WBeta-secretase 13.4.23.460.449
4i0h1BLBeta-secretase 13.4.23.460.449
4uocNCNCinA-like protein/0.449
4xguADPPutative pachytene checkpoint protein 2/0.449
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.449
4djhJDCKappa-type opioid receptor/0.449
1dr2TAPDihydrofolate reductase1.5.1.30.448
2b53D23Cyclin-dependent kinase 22.7.11.220.448
2fznFADBifunctional protein PutA1.5.5.20.448
2hydADPPutative multidrug export ATP-binding/permease protein SAV18663.6.30.448
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.448
2irzI02Beta-secretase 13.4.23.460.448
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.448
3qbhQBHBeta-secretase 13.4.23.460.448
4eagATP5'-AMP-activated protein kinase subunit gamma-1/0.448
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.448
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.448
1beuIPLTryptophan synthase alpha chain/0.447
1lwiNAP3-alpha-hydroxysteroid dehydrogenase1.1.1.500.447
1omoNADAlanine dehydrogenase/0.447
1xkvATPPhosphoenolpyruvate carboxykinase (ATP)/0.447
1xl5190Gag-Pol polyprotein3.4.23.160.447
2b3dFADModulator of drug activity B/0.447
2b4tAESGlyceraldehyde-3-phosphate dehydrogenase/0.447
2fgjATPAlpha-hemolysin translocation ATP-binding protein HlyB/0.447
2g1o2IGRenin3.4.23.150.447
3dh7FMNIsopentenyl-diphosphate delta-isomerase/0.447
3eheNADUDP-glucose 4-epimerase (GalE-1)/0.447
3frqERYErythromycin resistance repressor protein/0.447
3o0o5ADVitamin B12-dependent ribonucleotide reductase/0.447
3s5wFADL-ornithine N(5)-monooxygenase/0.447
3sufSUEPolyprotein/0.447
4dx9SER_ALA_VAL_THRIntegrin beta-1/0.447
4dx9SER_ALA_VAL_THRIntegrin beta-1-binding protein 1/0.447
1m78NDPDihydrofolate reductase1.5.1.30.446
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.446
1tj0FADBifunctional protein PutA1.5.5.20.446
1x1bSAHC-20 methyltransferase/0.446
2a87FADThioredoxin reductase1.8.1.90.446
2npiATPmRNA cleavage and polyadenylation factor CLP1/0.446
2uxoTACHTH-type transcriptional regulator TtgR/0.446
2w06FRVCyclin-dependent kinase 22.7.11.220.446
2y65ADPKinesin heavy chain/0.446
3gwfNAPCyclohexanone monooxygenase/0.446
3lu1NADUDP-N-acetylglucosamine 4-epimerase/0.446
3m2vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.446
3mvqNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.446
3pwm017Gag-Pol polyprotein3.4.23.160.446
3rbaCODPhosphopantetheine adenylyltransferase/0.446
3up4FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.446
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.446
4d89BXDBeta-secretase 13.4.23.460.446
4ejvLCLTranscriptional regulator TcaR/0.446
4jlj1NMDeoxycytidine kinase2.7.1.740.446
4nd4NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.446
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.446
5eaiFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.446
1c7oPPGHemolysin/0.445
1q5mNDPProstaglandin-E(2) 9-reductase1.1.1.1890.445
1tehNADAlcohol dehydrogenase class-31.1.1.10.445
1udbUFGUDP-glucose 4-epimerase5.1.3.20.445
2dgnDOIAdenylosuccinate synthetase isozyme 1/0.445
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.445
2g247IGRenin3.4.23.150.445
2ivnANPtRNA N6-adenosine threonylcarbamoyltransferase/0.445
2y99NADCis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase1.3.1.560.445
2ym2NAPPhenylacetone monooxygenase1.14.13.920.445
3a0tADPSensor histidine kinase/0.445
3jv7NADSecondary alcohol dehydrogenase/0.445
3kb1ADPIron-sulfur cluster carrier protein/0.445
3qfrFMNNADPH--cytochrome P450 reductase/0.445
3toxNAPPutative oxidoreductase/0.445
3umpATPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.445
3ut5LOCTubulin beta chain/0.445
3vt7VDXVitamin D3 receptor/0.445
4acxS8ZBeta-secretase 13.4.23.460.445
4bb3KKAIsopenicillin N synthase1.21.3.10.445
4hbgNDP3-oxoacyl-[acyl-carrier-protein] reductase1.1.1.1000.445
4m4922YL-lactate dehydrogenase A chain1.1.1.270.445
4wsoNADProbable nicotinate-nucleotide adenylyltransferase/0.445
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.445
1ja1FMNNADPH--cytochrome P450 reductase/0.444
1n2sNAIdTDP-4-dehydrorhamnose reductase1.1.1.1330.444
1nzfUPGDNA beta-glucosyltransferase/0.444
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.444
1qjfACSIsopenicillin N synthase1.21.3.10.444
1ri1GTGmRNA cap guanine-N7 methyltransferase2.1.1.560.444
2ag5NAD3-hydroxybutyrate dehydrogenase type 2/0.444
2c54NADGDP-mannose 3,5-epimerase5.1.3.180.444
2fonFADAcyl-coenzyme A oxidase/0.444
2g1n1IGRenin3.4.23.150.444
2op9WR1Orf1ab polyprotein/0.444
2pzjNADPutative nucleotide sugar epimerase/ dehydratase/0.444
2xx91NFGlutamate receptor 2/0.444
3pm1ETHTH-type transcriptional regulator QacR/0.444
3to6LYS_CMCHistone acetyltransferase ESA1/0.444
4bcaFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.444
4fw8NAI3-oxoacyl-(Acyl-carrier-protein) reductase/0.444
4lcjNADC-terminal-binding protein 2/0.444
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.444
1b2lNDCAlcohol dehydrogenase1.1.1.10.443
1gzuNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.443
1msmJE2Gag-Pol polyprotein3.4.23.160.443
1obbNADAlpha-glucosidase3.2.1.200.443
1xl8152Peroxisomal carnitine O-octanoyltransferase2.3.1.1370.443
1y7lASN_LEU_ASN_ILECysteine synthase2.5.1.470.443
2ebaFADPutative glutaryl-CoA dehydrogenase/0.443
2fn7NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.443
2ien017Gag-Pol polyprotein3.4.23.160.443
2iko7IGRenin3.4.23.150.443
2jb4A14Isopenicillin N synthase1.21.3.10.443
2npfMOUElongation factor 2/0.443
2ovhAS0Progesterone receptor/0.443
2q1uNADPutative nucleotide sugar epimerase/ dehydratase/0.443
2wnsOMPUridine 5'-monophosphate synthase2.4.2.100.443
2yq92AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.443
3a1nNADNDP-sugar epimerase/0.443
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.443
3hyoADPPyridoxal kinase/0.443
3oqfS51Renin3.4.23.150.443
3own3OWRenin3.4.23.150.443
3phiNDPShikimate dehydrogenase (NADP(+))/0.443
3rsv3RSBeta-secretase 13.4.23.460.443
3s1dZIRCytokinin dehydrogenase 11.5.99.120.443
3zw9NADPeroxisomal bifunctional enzyme1.1.1.350.443
4bv9NDPKetimine reductase mu-crystallin1.5.1.250.443
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
4irnFADAnaB/0.443
4j7uNAPSepiapterin reductase1.1.1.1530.443
4qaiFMNNADPH dehydrogenase/0.443
5hwqCAAHydroxymethylglutaryl-CoA synthase/0.443
1drhNAPDihydrofolate reductase1.5.1.30.442
1e79ATPATP synthase subunit alpha, mitochondrial/0.442
1e79ATPATP synthase subunit beta, mitochondrial3.6.3.140.442
1fm4DXCMajor pollen allergen Bet v 1-L/0.442
1j1zATPArgininosuccinate synthase/0.442
1nooCAHCamphor 5-monooxygenase1.14.15.10.442
1phgMYTCamphor 5-monooxygenase1.14.15.10.442
1uzwCDHIsopenicillin N synthase1.21.3.10.442
2cv2GSUGlutamate--tRNA ligase6.1.1.170.442
2fzwNADAlcohol dehydrogenase class-31.1.1.10.442
2q46NAPUncharacterized protein At5g02240/0.442
2vbpVB1Isopenicillin N synthase1.21.3.10.442
2znpK55Peroxisome proliferator-activated receptor delta/0.442
3ensENSCoagulation factor X3.4.21.60.442
3il1B5DGlutamate receptor 2/0.442
3oibFDAPutative acyl-CoA dehydrogenase/0.442
3pvcFADtRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC/0.442
3rq6APRADP-dependent (S)-NAD(P)H-hydrate dehydratase/0.442
3rueNADUDP-N-acetylglucosamine 4-epimerase/0.442
3vdqNAD3-hydroxybutyrate dehydrogenase/0.442
3vswR31Renin3.4.23.150.442
4a81DXCMajor pollen allergen Bet v 1-A/0.442
4a87NARMajor pollen allergen Bet v 1-A/0.442
4fxfATPPyruvate kinase PKM2.7.1.400.442
4gyzD5MTyrosyl-DNA phosphodiesterase 23.1.40.442
4h3g10QBeta-secretase 13.4.23.460.442
4nd2A3DLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.442
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.442
4uwmFMN3,6-diketocamphane 1,6 monooxygenase1.14.130.442
5eioNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.442
5ftcADPTPR domain protein/0.442
1a72PADAlcohol dehydrogenase E chain1.1.1.10.441
1jueFMNDihydroorotate dehydrogenase A (fumarate)1.3.98.10.441
1nsgRADPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.441
1nsgRADSerine/threonine-protein kinase mTOR2.7.11.10.441
1oc1ASVIsopenicillin N synthase1.21.3.10.441
1vbiNADMalate/L-lactate dehydrogenase family protein/0.441
2a58RBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.441
2a92NAIL-lactate dehydrogenase/0.441
2ikuLIYRenin3.4.23.150.441
2om9AJAPeroxisome proliferator-activated receptor gamma/0.441
3a1cACPProbable copper-exporting P-type ATPase A3.6.3.540.441
3ruaNADUDP-N-acetylglucosamine 4-epimerase/0.441
3triNAPPyrroline-5-carboxylate reductase/0.441
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.441
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.441
4dfg0JVGag-Pol polyprotein3.4.23.160.441
4g74FADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.441
4gl4NAIAlcohol dehydrogenase class-3/0.441
4ohvANPProtein clpf-1/0.441
4yaoFMNNADPH--cytochrome P450 reductase/0.441
4yvz3ATDNA integrity scanning protein DisA/0.441
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.441
1dg8NDPDihydrofolate reductase1.5.1.30.440
1hncGDNGlutathione S-transferase Mu 22.5.1.180.440
2bf4FMNNADPH--cytochrome P450 reductase/0.440
2cnsACORibosomal-protein-alanine acetyltransferase/0.440
2ewmNAD(S)-1-Phenylethanol dehydrogenase1.1.1.3110.440
2ft9CHDFatty acid-binding protein 2, liver/0.440
2hpvFMNFMN-dependent NADH-azoreductase1.70.440
2w3bNDPDihydrofolate reductase1.5.1.30.440
3br3ETHTH-type transcriptional regulator QacR/0.440
3d3wNAPL-xylulose reductase1.1.1.100.440
3h2sNDPPutative NADH-flavin reductase/0.440
3i25MV7Beta-secretase 13.4.23.460.440
3iqhTYR_ASP_ILECysteine synthase2.5.1.470.440
3k8q22APurine nucleoside phosphorylase2.4.2.10.440
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.440
3pndFADFAD:protein FMN transferase/0.440
3r7kFDAProbable acyl CoA dehydrogenase/0.440
3w78CBDFMN-dependent NADH-azoreductase/0.440
4a84DXCMajor pollen allergen Bet v 1-A/0.440
4b65FADL-ornithine N(5)-monooxygenase/0.440
4b79NADProbable short-chain dehydrogenase/0.440
4cvmANPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.440
4iv6FDAIsovaleryl-CoA dehydrogenase/0.440
4panGDPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.440
4u0mGTPCyclic GMP-AMP synthase/0.440