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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1pwuGM6Lethal factor3.4.24.83

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1pwuGM6Lethal factor3.4.24.831.000
2a9z26AAdenosine kinase2.7.1.200.522
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.518
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.511
1yqy915Lethal factor3.4.24.830.506
1wuuANPGalactokinase2.7.1.60.500
1i59ANPChemotaxis protein CheA2.7.13.30.497
1xddAAYIntegrin alpha-L/0.496
2g8yNADHydroxycarboxylate dehydrogenase B/0.490
3g1rFIT3-oxo-5-beta-steroid 4-dehydrogenase/0.489
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.489
1kbo340NAD(P)H dehydrogenase [quinone] 11.6.5.20.488
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.488
5c93ACPTwo-component system histidine protein kinase/0.488
3e6eDCSAlanine racemase/0.487
5c1mCLRMu-type opioid receptor/0.487
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.485
4yau2AMNADPH--cytochrome P450 reductase/0.485
1x2hLPALipoate-protein ligase A6.3.1.200.483
1zg32HIIsoflavone 4'-O-methyltransferase/0.483
4iae1DXAlr2278 protein/0.482
3sl2ATPSensor histidine kinase WalK/0.481
4ycoFMNtRNA-dihydrouridine(16) synthase/0.481
2ahrNAPPyrroline-5-carboxylate reductase/0.480
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.480
4ipw1G7Mycocyclosin synthase1.14.21.90.480
2ab8MTPAdenosine kinase2.7.1.200.479
2emuSAHDiphthine synthase/0.479
3qeoLLTDeoxycytidine kinase2.7.1.740.479
4n1gCEIObelin/0.479
1c3x8IGPurine nucleoside phosphorylase2.4.2.10.478
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.478
3x2fNAIAdenosylhomocysteinase/0.478
4a83DXCMajor pollen allergen Bet v 1-A/0.478
7stdCRPScytalone dehydratase4.2.1.940.478
4bfxZVXPantothenate kinase2.7.1.330.477
1xl8152Peroxisomal carnitine O-octanoyltransferase2.3.1.1370.476
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.476
4dc0NDPPutative ketoacyl reductase1.3.10.476
4y93746Tyrosine-protein kinase/0.476
1xe55FEPlasmepsin-23.4.23.390.475
3cmfPDN3-oxo-5-beta-steroid 4-dehydrogenase/0.475
3e8xNAPBH1520 protein/0.475
1a9cGTPGTP cyclohydrolase 13.5.4.160.474
2ed3SAHDiphthine synthase/0.474
3l6jZ90Alr2278 protein/0.474
3uu114BAnthranilate phosphoribosyltransferase/0.474
4a802ANMajor pollen allergen Bet v 1-A/0.474
4bb3KKAIsopenicillin N synthase1.21.3.10.474
4xguADPPutative pachytene checkpoint protein 2/0.474
3ddnHPVD-3-phosphoglycerate dehydrogenase1.1.1.950.473
4du82P0Mevalonate diphosphate decarboxylase/0.473
4ycpFMNtRNA-dihydrouridine(16) synthase/0.473
1vbiNADMalate/L-lactate dehydrogenase family protein/0.472
2a9y26AAdenosine kinase2.7.1.200.472
2eeqSAHDiphthine synthase/0.471
2g1r3IGRenin3.4.23.150.471
4ambDUDPutative glycosyl transferase/0.471
4jqh1MFAlr2278 protein/0.471
4oztP1AEcdysone receptor, putative/0.471
1fx9MJIPhospholipase A2, major isoenzyme3.1.1.40.470
1kquBR4Phospholipase A2, membrane associated/0.470
1me6IVSPlasmepsin-23.4.23.390.470
3h3r14HCollagen type IV alpha-3-binding protein/0.470
3r1rATPRibonucleoside-diphosphate reductase 1 subunit alpha1.17.4.10.470
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.469
4mlp2CXCryptochrome-2/0.469
5f54TMPSingle-stranded-DNA-specific exonuclease/0.469
2pobGW4Peroxisome proliferator-activated receptor gamma/0.468
2xc3RT8Steroid C26-monooxygenase1.14.13.1410.468
2xtnGTPGTPase IMAP family member 2/0.468
3uylTYDProbable NDP-rhamnosyltransferase/0.468
3wleNAD(R)-specific carbonyl reductase/0.468
5cyoGDPSeptin-9/0.468
2hrcCHDFerrochelatase, mitochondrial4.99.1.10.467
3akm11DFatty acid-binding protein, intestinal/0.467
3ld6BCDLanosterol 14-alpha demethylase1.14.13.700.467
3m6iNADL-arabinitol 4-dehydrogenase1.1.1.120.467
4iah1DXAlr2278 protein/0.467
4jnkZHKL-lactate dehydrogenase A chain1.1.1.270.467
1rfuADPPyridoxal kinase2.7.1.350.466
2rlcCHDCholoylglycine hydrolase3.5.1.240.466
3q44D50M1 family aminopeptidase3.4.110.466
3qi4IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.466
3vqsJT1Genome polyprotein/0.466
3ziaADPATP synthase subunit beta, mitochondrial3.6.3.140.466
4bftZVTPantothenate kinase2.7.1.330.466
1nj5P5AProline--tRNA ligase/0.465
2du2FMNLactate oxidase/0.465
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.465
2hunNAD336aa long hypothetical dTDP-glucose 4,6-dehydratase/0.465
2uxoTACHTH-type transcriptional regulator TtgR/0.465
3b9lAZZSerum albumin/0.465
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.465
3vtdTKDVitamin D3 receptor/0.465
4dpuAGSMevalonate diphosphate decarboxylase/0.465
1cilETSCarbonic anhydrase 24.2.1.10.464
1psa0ZLPepsin A3.4.23.10.464
1uvsI11Prothrombin3.4.21.50.464
2il2LIXRenin3.4.23.150.464
2pb6SAHDiphthine synthase/0.464
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.464
3ebiBEYM1 family aminopeptidase3.4.110.464
3in6FMNUncharacterized protein/0.464
3pfdFDAAcyl-CoA dehydrogenase FadE25/0.464
4fgcPQ0NADPH-dependent 7-cyano-7-deazaguanine reductase1.7.1.130.464
1sqkLARActin, alpha skeletal muscle/0.463
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.463
2rqfJH3Hemolymph juvenile hormone binding protein/0.463
3rdqDTBStreptavidin/0.463
3zeiAWHO-acetylserine sulfhydrylase/0.463
4a8v2ANMajor pollen allergen Bet v 1-J/0.463
4bfzZVZPantothenate kinase2.7.1.330.463
4fxy0W2Neurolysin, mitochondrial3.4.24.160.463
1gzuNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.462
2x06NADL-sulfolactate dehydrogenase/0.462
3h3t16HCollagen type IV alpha-3-binding protein/0.462
3phjDHKShikimate dehydrogenase (NADP(+))/0.462
3pqbVGPPutative oxidoreductase/0.462
3rbaCODPhosphopantetheine adenylyltransferase/0.462
4m4922YL-lactate dehydrogenase A chain1.1.1.270.462
4u0sADPAdenosine monophosphate-protein transferase FICD2.7.7.n10.462
4xsvCTPEthanolamine-phosphate cytidylyltransferase2.7.7.140.462
1l8qADPChromosomal replication initiator protein DnaA/0.461
2cftPLPPyridoxal phosphate phosphatase/0.461
2dxvSAHDiphthine synthase/0.461
2xf3J01Uncharacterized protein/0.461
3a1cACPProbable copper-exporting P-type ATPase A3.6.3.540.461
3apwDP0Alpha-1-acid glycoprotein 2/0.461
3lfm3DTAlpha-ketoglutarate-dependent dioxygenase FTO/0.461
3qizQI2Botulinum neurotoxin type A3.4.24.690.461
4df2FMNNADPH dehydrogenase/0.461
1hfqMOTDihydrofolate reductase1.5.1.30.460
1jedADPSulfate adenylyltransferase/0.460
2a84ATPPantothenate synthetase6.3.2.10.460
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.460
2cekN8TAcetylcholinesterase3.1.1.70.460
2h3wHC5Carnitine O-acetyltransferase2.3.1.70.460
3br3ETHTH-type transcriptional regulator QacR/0.460
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.460
4a2aATPCell division protein FtsA/0.460
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.460
4ips1G4Mycocyclosin synthase1.14.21.90.460
4qxr1YEStimulator of interferon genes protein/0.460
1w6hTITPlasmepsin-23.4.23.390.459
2ea2F77Methionine aminopeptidase 2/0.459
2ewmNAD(S)-1-Phenylethanol dehydrogenase1.1.1.3110.459
2hk9NAPShikimate dehydrogenase (NADP(+))/0.459
2hp2KE4Glutamate-1-semialdehyde 2,1-aminomutase5.4.3.80.459
2vatCOAAcetyl-CoA--deacetylcephalosporin C acetyltransferase2.3.1.1750.459
2ym1FADPhenylacetone monooxygenase1.14.13.920.459
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.459
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.459
3wagTYDGlycosyltransferase/0.459
1ay0TPPTransketolase 12.2.1.10.458
1bntAL2Carbonic anhydrase 24.2.1.10.458
1fm4DXCMajor pollen allergen Bet v 1-L/0.458
1hncGDNGlutathione S-transferase Mu 22.5.1.180.458
1qiqACCIsopenicillin N synthase1.21.3.10.458
1xe65FPPlasmepsin-23.4.23.390.458
2gevCOKPantothenate kinase2.7.1.330.458
3ewkFADSensory box histidine kinase/response regulator/0.458
3ivcFG4Pantothenate synthetase6.3.2.10.458
3lu1NADUDP-N-acetylglucosamine 4-epimerase/0.458
3pe2E1BCasein kinase II subunit alpha2.7.11.10.458
3vf60H6Glucokinase2.7.1.20.458
4hbgNDP3-oxoacyl-[acyl-carrier-protein] reductase1.1.1.1000.458
4p9dTMPDeoxycytidylate deaminase/0.458
4u07ATPAdenosine monophosphate-protein transferase FICD2.7.7.n10.458
6stdMS2Scytalone dehydratase4.2.1.940.458
5uviZMAAdenosine receptor A2a/0.458
1g1aNADdTDP-glucose 4,6-dehydratase/0.457
1yw8A75Methionine aminopeptidase 2/0.457
2dsgSAHDiphthine synthase/0.457
2e8hSAHDiphthine synthase/0.457
2ejzSAHDiphthine synthase/0.457
2x7hPFNProstaglandin reductase 310.457
3zvmADPBifunctional polynucleotide phosphatase/kinase2.7.1.780.457
4a84DXCMajor pollen allergen Bet v 1-A/0.457
4lb2DM5Serum albumin/0.457
4yal2AMNADPH--cytochrome P450 reductase/0.457
1dmyAZMCarbonic anhydrase 5A, mitochondrial4.2.1.10.456
2eniSAHDiphthine synthase/0.456
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.456
2ym2FADPhenylacetone monooxygenase1.14.13.920.456
2yq92AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.456
3g5hYTTMycocyclosin synthase1.14.21.90.456
3ieuGDPGTPase Era/0.456
3iktNADRedox-sensing transcriptional repressor Rex/0.456
3o03NAPDehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase)/0.456
3qvrFADGlucose oxidase1.1.3.40.456
4e5yNDPGDP-L-fucose synthase1.1.1.2710.456
4xr9NADCalS8/0.456
1gveNAPAflatoxin B1 aldehyde reductase member 310.455
1hdoNAPFlavin reductase (NADPH)/0.455
2bxoOPBSerum albumin/0.455
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.455
2e15SAHDiphthine synthase/0.455
2emrSAHDiphthine synthase/0.455
2ivnANPtRNA N6-adenosine threonylcarbamoyltransferase/0.455
2jizANPATP synthase subunit beta, mitochondrial3.6.3.140.455
2ylxFADPhenylacetone monooxygenase1.14.13.920.455
3tjzGNPADP-ribosylation factor 1/0.455
3vrbFTNSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial/0.455
3vrbFTNCytochrome b-large subunit/0.455
3zbsOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.455
4b1rITCTetracycline repressor protein class D/0.455
4prxADPDNA gyrase subunit B/0.455
4uymVOR14-alpha sterol demethylase Cyp51B/0.455
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.454
1xvaSAMGlycine N-methyltransferase2.1.1.200.454
2c29NAPDihydroflavonol 4-reductase/0.454
2g226IGRenin3.4.23.150.454
2nr4FMNConserved protein/0.454
2pcaSAHDiphthine synthase/0.454
2q1uNADPutative nucleotide sugar epimerase/ dehydratase/0.454
2z7hGG3Geranylgeranyl pyrophosphate synthase/0.454
3ojxFADNADPH--cytochrome P450 reductase/0.454
3oqfS51Renin3.4.23.150.454
3q43D66M1 family aminopeptidase3.4.110.454
3upkUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.454
3v0p4GWHisto-blood group ABO system transferase/0.454
3zs7ATPPyridoxine/pyridoxal/pyridoxamine kinase/0.454
4bfuZVUPantothenate kinase2.7.1.330.454
4bfvZVVPantothenate kinase2.7.1.330.454
4ey6GNTAcetylcholinesterase3.1.1.70.454
1lf2R37Plasmepsin-23.4.23.390.453
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.453
2a5kAZPReplicase polyprotein 1ab3.4.220.453
2dxwSAHDiphthine synthase/0.453
2e07SAHDiphthine synthase/0.453
2hydADPPutative multidrug export ATP-binding/permease protein SAV18663.6.30.453
2qbuSAHPrecorrin-2 methyltransferase/0.453
2vaxCSCAcetyl-CoA--deacetylcephalosporin C acetyltransferase2.3.1.1750.453
2zxgS23Aminopeptidase N3.4.11.20.453
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.453
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.453
3fhxPXLPyridoxal kinase2.7.1.350.453
3uzxAOX3-oxo-5-beta-steroid 4-dehydrogenase/0.453
4k13ETSCarbonic anhydrase 24.2.1.10.453
1rywEPUUDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.452
1sd1FMCS-methyl-5'-thioadenosine phosphorylase/0.452
1yqxNAPSinapyl alcohol dehydrogenase/0.452
2cjfRP43-dehydroquinate dehydratase4.2.1.100.452
2e8sSAHDiphthine synthase/0.452
2iviACWIsopenicillin N synthase1.21.3.10.452
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.452
3h3qH13Collagen type IV alpha-3-binding protein/0.452
3jusBCDLanosterol 14-alpha demethylase1.14.13.700.452
4a87NARMajor pollen allergen Bet v 1-A/0.452
4b65FADL-ornithine N(5)-monooxygenase/0.452
4cukNAID-lactate dehydrogenase/0.452
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.452
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.452
4hn1TYDdTDP-4-dehydro-6-deoxyglucose 3-epimerase5.1.3.270.452
4ubtCOASteroid 3-ketoacyl-CoA thiolase/0.452
1gc5ADPADP-dependent glucokinase2.7.1.1470.451
1h73ANPHomoserine kinase2.7.1.390.451
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.451
1q12ATPMaltose/maltodextrin import ATP-binding protein MalK/0.451
1qlhNADAlcohol dehydrogenase E chain1.1.1.10.451
2abaSTRPentaerythritol tetranitrate reductase/0.451
2eldSAHDiphthine synthase/0.451
2g1y5IGRenin3.4.23.150.451
2pchSAHDiphthine synthase/0.451
2q7oIMHPurine nucleoside phosphorylase2.4.2.10.451
2zevIPEGeranylgeranyl pyrophosphate synthase/0.451
4dptAGSMevalonate diphosphate decarboxylase/0.451
4l0qNADAlcohol dehydrogenase class-3/0.451
4m83ERYOleandomycin glycosyltransferase2.4.10.451
4n6hEJ4Delta-type opioid receptor/0.451
5bylGCPBifunctional AAC/APH2.3.10.451
1ahiCHO7-alpha-hydroxysteroid dehydrogenase1.1.1.1590.450
1rftPXMPyridoxal kinase2.7.1.350.450
2a58RBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.450
2e16SAHDiphthine synthase/0.450
2e4nSAHDiphthine synthase/0.450
2ntrL00Beta-secretase 13.4.23.460.450
2owvSAHDiphthine synthase/0.450
2p6lSAHDiphthine synthase/0.450
2pnjCHDFerrochelatase, mitochondrial4.99.1.10.450
2yphQQY2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.450
3b6pTMPThree-prime repair exonuclease 13.1.11.20.450
3keqNADRedox-sensing transcriptional repressor Rex/0.450
3td7FADProbable FAD-linked sulfhydryl oxidase R5961.8.3.20.450
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.450
4l9q9TPSerum albumin/0.450
4tyqAP5Adenylate kinase/0.450
4yaoFMNNADPH--cytochrome P450 reductase/0.450
1adfTADAlcohol dehydrogenase E chain1.1.1.10.449
1h60STRPentaerythritol tetranitrate reductase/0.449
1h65GDPTranslocase of chloroplast 343.6.50.449
1i5bANPChemotaxis protein CheA2.7.13.30.449
1ja0FADNADPH--cytochrome P450 reductase/0.449
1lkeDOGBilin-binding protein/0.449
1pjcNADAlanine dehydrogenase/0.449
1tqf32PBeta-secretase 13.4.23.460.449
1wngSAHDiphthine synthase/0.449
2a57CRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.449
2a94AP0L-lactate dehydrogenase1.1.1.270.449
2b8v3BNBeta-secretase 13.4.23.460.449
2bf4FMNNADPH--cytochrome P450 reductase/0.449
2ddoATPPyridoxine/pyridoxal/pyridoxamine kinase/0.449
2e7zMGDAcetylene hydratase/0.449
2jj2ANPATP synthase subunit beta, mitochondrial3.6.3.140.449
2pj4414Carboxypeptidase B/0.449
2rbeZMGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.449
2v5aLZLBiotin carboxylase6.3.4.140.449
2y60M8FIsopenicillin N synthase1.21.3.10.449
3gw9VNILanosterol 14-alpha-demethylase/0.449
3u9fCLMChloramphenicol acetyltransferase2.3.1.280.449
3up5FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.449
4c0bATPmRNA cleavage and polyadenylation factor CLP1/0.449
4fhd0TTSpore photoproduct lyase/0.449
4g3jVNTLanosterol 14-alpha-demethylase/0.449
4in44IDKelch-like ECH-associated protein 1/0.449
4jnkNAIL-lactate dehydrogenase A chain1.1.1.270.449
4xba5GPAprataxin-like protein30.449
1c7oPPGHemolysin/0.448
1gtrATPGlutamine--tRNA ligase6.1.1.180.448
1tl7ONMAdenylate cyclase type 2/0.448
1tl7ONMAdenylate cyclase type 5/0.448
2dvlFADAcyl-CoA dehydrogenase/0.448
2pamTYDTDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase5.3.2.30.448
2ydd2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.448
2yj5ATPCopper-transporting ATPase/0.448
3fr5I4AFatty acid-binding protein, adipocyte/0.448
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.448
3ozc4CTS-methyl-5'-thioadenosine phosphorylase/0.448
3p62FMNPentaerythritol tetranitrate reductase/0.448
3r7kFDAProbable acyl CoA dehydrogenase/0.448
3t82SG4Carbonic anhydrase 24.2.1.10.448
3tr05GPGuanylate kinase/0.448
4eakATP5'-AMP-activated protein kinase subunit gamma-1/0.448
4eji0QACytochrome P450 2A131.14.14.10.448
4eywL0RCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.448
4fw8NAI3-oxoacyl-(Acyl-carrier-protein) reductase/0.448
4i6aHMG3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.448
4klaCHDFerrochelatase, mitochondrial4.99.1.10.448
4ktl1CQCytochrome P450/0.448
4rww2BALmo2692 protein/0.448
4tx9AMZPhosphoribosyl isomerase A/0.448
4xmxBESAminopeptidase N3.4.11.20.448
5stdUNNScytalone dehydratase4.2.1.940.448
6gsuGPSGlutathione S-transferase Mu 12.5.1.180.448
1f17NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.447
1ivsVAAValine--tRNA ligase6.1.1.90.447
1o2g696Prothrombin3.4.21.50.447
1q0zAKAAclacinomycin methylesterase RdmC3.1.1.950.447
1sq5ADPPantothenate kinase2.7.1.330.447
1y7lASN_LEU_ASN_ILECysteine synthase2.5.1.470.447
2g25TDKPyruvate dehydrogenase E1 component1.2.4.10.447
2hxzH7JCathepsin S3.4.22.270.447
2iyfERYOleandomycin glycosyltransferase2.4.10.447
2lfoGCHFatty acid-binding protein, liver/0.447
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.447
2w6cBM4Acetylcholinesterase3.1.1.70.447
2zsaADPPantothenate kinase2.7.1.330.447
3gncQQQGlutaryl-CoA dehydrogenase/0.447
3hy9098A disintegrin and metalloproteinase with thrombospondin motifs 53.4.240.447
3lkhLT6Genome polyprotein2.7.7.480.447
3mddFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.447
3uxvGUNNADPH-dependent 7-cyano-7-deazaguanine reductase/0.447
3zoiM2WIsopenicillin N synthase1.21.3.10.447
3zv7NHGAcetylcholinesterase3.1.1.70.447
4a6nFADTetX family tetracycline inactivation enzyme/0.447
4a81DXCMajor pollen allergen Bet v 1-A/0.447
4d9fDCSD-cysteine desulfhydrase/0.447
4gv4MEJPoly [ADP-ribose] polymerase 32.4.2.300.447
4rh10TTSpore photoproduct lyase/0.447
4wucANPDNA gyrase subunit B/0.447
1beuIPLTryptophan synthase alpha chain/0.446
1cqp803Integrin alpha-L/0.446
1d3dBZTProthrombin3.4.21.50.446
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.446
1drhNAPDihydrofolate reductase1.5.1.30.446
1fxfMJIPhospholipase A2, major isoenzyme3.1.1.40.446
1gj5130Prothrombin3.4.21.50.446
1h22E10Acetylcholinesterase3.1.1.70.446
1mxfMTXPutative pteridine reductase 2/0.446
1n3rGTPGTP cyclohydrolase 13.5.4.160.446
1qtiGNTAcetylcholinesterase3.1.1.70.446
1yb5NAPQuinone oxidoreductase1.6.5.50.446
2bbwGP5Adenylate kinase 4, mitochondrial/0.446
2c20NADUDP-glucose 4-epimerase/0.446
2gstGPSGlutathione S-transferase Mu 12.5.1.180.446
2owgSAHDiphthine synthase/0.446
2pauD5M5'-deoxynucleotidase YfbR/0.446
3gonANPPhosphomevalonate kinase/0.446
3gwfNAPCyclohexanone monooxygenase/0.446
3hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.446
3p0fBAUUridine phosphorylase 22.4.2.30.446
3pduNAPGlyoxalate/3-oxopropanoate/4-oxobutanoate reductase/0.446
3qgf46FGenome polyprotein2.7.7.480.446
3qykIE2Carbonic anhydrase 24.2.1.10.446
3tzaTZGGlutamate receptor 2/0.446
4fl0PLPAminotransferase ALD1, chloroplastic2.6.10.446
4g9kFADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.446
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.446
4jlm1NNDeoxycytidine kinase2.7.1.740.446
4mrm2BYGamma-aminobutyric acid type B receptor subunit 1/0.446
4na4A1RPoly(ADP-ribose) glycohydrolase3.2.1.1430.446
4yvz3ATDNA integrity scanning protein DisA/0.446
4z63ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.446
5kwvANPPantothenate synthetase/0.446
1m8jNADNicotinamide-nucleotide adenylyltransferase2.7.7.10.445
1m8kNADNicotinamide-nucleotide adenylyltransferase2.7.7.10.445
1n5qTNCActVA 6 protein/0.445
1obbNADAlpha-glucosidase3.2.1.200.445
1qrtATPGlutamine--tRNA ligase6.1.1.180.445
1r8bATPCCA-adding enzyme2.7.7.720.445
1touB1VFatty acid-binding protein, adipocyte/0.445
1u1f183Uridine phosphorylase2.4.2.30.445
1w19T5P6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.445
2d3aADPGlutamine synthetase root isozyme 36.3.1.20.445
2dv3SAHDiphthine synthase/0.445
2eglSAHDiphthine synthase/0.445
2gtbAZPOrf1ab polyprotein/0.445
2huxSAHDiphthine synthase/0.445
2is0I03Beta-secretase 13.4.23.460.445
2j83BATUlilysin3.4.240.445
2owfSAHDiphthine synthase/0.445
2p2xSAHDiphthine synthase/0.445
2vwqNAPGlucose 1-dehydrogenase/0.445
2xszATPRuvB-like 23.6.4.120.445
2xupTZ5Acetylcholinesterase3.1.1.70.445
3ekuCY9Actin-5C/0.445
3jynNDPQuinone oxidoreductase/0.445
3mjrAC2Deoxycytidine kinase2.7.1.740.445
3nbvANPKetohexokinase/0.445
3oqkS52Renin3.4.23.150.445
3qe2FMNNADPH--cytochrome P450 reductase/0.445
3raiX85Cyclin-dependent kinase 22.7.11.220.445
3v0o4GWHisto-blood group ABO system transferase/0.445
4a2zVIQGlycylpeptide N-tetradecanoyltransferase/0.445
4bf9FMNtRNA-dihydrouridine(16) synthase/0.445
4fj0HHF17beta-hydroxysteroid dehydrogenase/0.445
4jyzATPGlutamine--tRNA ligase6.1.1.180.445
4oqyNDP(S)-imine reductase/0.445
4rlh0WEEnoyl-[acyl-carrier-protein] reductase [NADH]/0.445
4ruoBIVVitamin D3 receptor A/0.445
4x7wMVIMycinamicin III 3''-O-methyltransferase2.1.1.2370.445
4yp6NAPNicotinamide-nucleotide adenylyltransferase2.7.7.10.445
5hwrCOAHydroxymethylglutaryl-CoA synthase/0.445
4z36ON3Lysophosphatidic acid receptor 1/0.445
1e2nRCAThymidine kinase/0.444
1eioGCHGastrotropin/0.444
1nm6L86Prothrombin3.4.21.50.444
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.444
1qrpHH0Pepsin A-43.4.23.10.444
1qx4FADNADH-cytochrome b5 reductase 31.6.2.20.444
1zgbA1EAcetylcholinesterase3.1.1.70.444
2e08SAHDiphthine synthase/0.444
2e1mFADL-glutamate oxidase/0.444
2fgjATPAlpha-hemolysin translocation ATP-binding protein HlyB/0.444
2j3qTFLAcetylcholinesterase3.1.1.70.444
2r6gATPMaltose/maltodextrin import ATP-binding protein MalK/0.444
2x7tWZBCarbonic anhydrase 24.2.1.10.444
2xb9XNW3-dehydroquinate dehydratase4.2.1.100.444
3aezGDPPantothenate kinase2.7.1.330.444
3af0GDPPantothenate kinase2.7.1.330.444
3b6zCO7Enoyl reductase LovC10.444
3ixp834Ecdysone receptor/0.444
3qt62P0Mevalonate diphosphate decarboxylase/0.444
3uhmRFNUDP-3-O-acyl-N-acetylglucosamine deacetylase/0.444
3vthAP2Carbamoyltransferase/0.444
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.444
4ddhMS0Pantothenate synthetase6.3.2.10.444
4mr72BVGamma-aminobutyric acid type B receptor subunit 1/0.444
4qx5CMPcGMP-dependent protein kinase 12.7.11.120.444
4xyeNADFormate dehydrogenase/0.444
4yaw2AMNADPH--cytochrome P450 reductase/0.444
1bwsNDPGDP-L-fucose synthase/0.443
1g54FFBCarbonic anhydrase 24.2.1.10.443
1gky5GPGuanylate kinase2.7.4.80.443
1hkuNADC-terminal-binding protein 11.1.10.443
1hygNAPL-2-hydroxycarboxylate dehydrogenase (NAD(P)(+))/0.443
1n3sGTPGTP cyclohydrolase 13.5.4.160.443
1qjfACSIsopenicillin N synthase1.21.3.10.443
1u1cBAUUridine phosphorylase2.4.2.30.443
2dshSAHDiphthine synthase/0.443
2f3rG5PGuanylate kinase2.7.4.80.443
2fxv5GPXanthine phosphoribosyltransferase2.4.2.220.443
2g1s4IGRenin3.4.23.150.443
2ktdPUCProstaglandin-H2 D-isomerase5.3.99.20.443
2pcgSAHDiphthine synthase/0.443
2q46NAPUncharacterized protein At5g02240/0.443
2qw034Z4-chlorobenzoyl CoA ligase/0.443
2x0iNAIMalate dehydrogenase/0.443
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.443
2yimMC4Probable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase )/0.443
3au2DGTDNA polymerase beta family (X family)/0.443
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.443
3cotSTR3-oxo-5-beta-steroid 4-dehydrogenase/0.443
3d4pNADL-lactate dehydrogenase 11.1.1.270.443
3d84NDPDihydrofolate reductase1.5.1.30.443
3mdzEZLCarbonic anhydrase 74.2.1.10.443
4ku7PCGcGMP-dependent protein kinase 12.7.11.120.443
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.443
5d7q4I5NAD-dependent protein deacetylase sirtuin-23.5.10.443
1f0lAPUDiphtheria toxin/0.442
1ju2FAD(R)-mandelonitrile lyase 24.1.2.100.442
1t2cNAIL-lactate dehydrogenase1.1.1.270.442
1u8vFAD4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase/0.442
1v35NAIEnoyl-ACP reductase/0.442
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.442
2bxfDZPSerum albumin/0.442
2e8qSAHDiphthine synthase/0.442
2fzwNADAlcohol dehydrogenase class-31.1.1.10.442
2g0gSP0Peroxisome proliferator-activated receptor gamma/0.442
2j9fTHV2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial1.2.4.40.442
2j9fTHV2-oxoisovalerate dehydrogenase subunit beta, mitochondrial1.2.4.40.442
2op9WR1Orf1ab polyprotein/0.442
2pcmSAHDiphthine synthase/0.442
2q5g1FAPeroxisome proliferator-activated receptor delta/0.442
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.442
2zbaZBATrichothecene 3-O-acetyltransferase/0.442
3bk2U5PRibonuclease J/0.442
3dhaC6LN-acyl homoserine lactonase AiiA3.1.1.810.442
3gqvNAPEnoyl reductase LovC10.442
3ig6438Urokinase-type plasminogen activator3.4.21.730.442
3imgBZ3Pantothenate synthetase6.3.2.10.442
3qv1NADGlyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic1.2.1.130.442
3uk6ADPRuvB-like 23.6.4.120.442
3uozFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.442
3w1wCHDFerrochelatase, mitochondrial4.99.1.10.442
3w8rACPUridine kinase/0.442
4lutDCSAlanine racemase/0.442
4qemHC4Phospholipase A2 VRV-PL-VIIIa/0.442
4tqgNDPPutative dTDP-d-glucose 4 6-dehydratase/0.442
5eioNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.442
4zj8SUVOrexin receptor type 1/0.442
1bnnAL1Carbonic anhydrase 24.2.1.10.441
1dcyI3NPhospholipase A2, membrane associated/0.441
1enoNADEnoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic1.3.1.90.441
1ld7U66Protein farnesyltransferase subunit beta2.5.1.580.441
1lf3EH5Plasmepsin-23.4.23.390.441
1mj9COAHistone acetyltransferase ESA1/0.441
1opmIYGPeptidyl-glycine alpha-amidating monooxygenase1.14.17.30.441
1uaeUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.441
1w4lGL8Acetylcholinesterase3.1.1.70.441
1ygjRMCPyridoxal kinase2.7.1.350.441
2ax4ADPBifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 22.7.1.250.441
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
2dxiATPGlutamate--tRNA ligase6.1.1.170.441
2jlbUDMUncharacterized protein/0.441
2pidYSATyrosine--tRNA ligase, mitochondrial6.1.1.10.441
2zi53L1Deoxycytidine kinase2.7.1.740.441
3a0tADPSensor histidine kinase/0.441
3c3xNAPEugenol synthase 11.1.1.3180.441
3coz54HPantothenate synthetase6.3.2.10.441
3fstFAD5,10-methylenetetrahydrofolate reductase1.5.1.200.441
3hl0NADMaleylacetate reductase/0.441
3ho9N3A3-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.441
3mjeNDPAmphB/0.441
3qiyQI1Botulinum neurotoxin type A3.4.24.690.441
3swqEPUUDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.441
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.441
4f9fGDPPutative glycosyltransferase/0.441
4h8004TAldehyde dehydrogenase, dimeric NADP-preferring/0.441
4la7A1OAbscisic acid receptor PYL2/0.441
4oe4NADDelta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial1.2.1.880.441
1h66RH1NAD(P)H dehydrogenase [quinone] 11.6.5.20.440
1i9qIOFCarbonic anhydrase 24.2.1.10.440
1kfbIGPTryptophan synthase alpha chain/0.440
1lbcCYZGlutamate receptor 2/0.440
1nlmUD1UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase/0.440
1oc1ASVIsopenicillin N synthase1.21.3.10.440
1r5hAO2Methionine aminopeptidase 2/0.440
1r6tTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.440
1votHUPAcetylcholinesterase3.1.1.70.440
1yqzCOACoenzyme A disulfide reductase/0.440
2a1hGBNBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.440
2ebaFADPutative glutaryl-CoA dehydrogenase/0.440
2ikuLIYRenin3.4.23.150.440
2npxNADNADH peroxidase1.11.1.10.440
2p6kSAHDiphthine synthase/0.440
2q4bNAPUncharacterized protein At5g02240/0.440
2rl1UD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.440
2vbdV10Isopenicillin N synthase1.21.3.10.440
2zynBCDPeriplasmic binding protein/0.440
3cosNADAlcohol dehydrogenase 41.1.1.10.440
3dcsMZMCarbonic anhydrase 24.2.1.10.440
3dhbC6LN-acyl homoserine lactonase AiiA3.1.1.810.440
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.440
3mhoJ43Carbonic anhydrase 24.2.1.10.440
3mpjFADGlutaryl-CoA dehydrogenase1.3.99.320.440
3rvhHQ2Lysine-specific demethylase 4A1.14.110.440
3w33W19Epidermal growth factor receptor2.7.10.10.440
3wrjCAMCamphor 5-monooxygenase1.14.15.10.440
3zsh469Mitogen-activated protein kinase 14/0.440
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
4ayy9MXProthrombin3.4.21.50.440
4bgiI4IEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
4d9eLCSD-cysteine desulfhydrase/0.440
4dbzNDPPutative ketoacyl reductase1.3.10.440
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.440
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.440
4rvfTYDD-mycarose 3-C-methyltransferase/0.440
5dbfNDPIridoid synthase1.3.1.990.440