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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4h3pANPMitogen-activated protein kinase 12.7.11.24

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4h3pANPMitogen-activated protein kinase 12.7.11.241.000
4fv8E63Mitogen-activated protein kinase 12.7.11.240.596
4h3qANPMitogen-activated protein kinase 12.7.11.240.577
3teiANPMitogen-activated protein kinase 12.7.11.240.567
4nifANPMitogen-activated protein kinase 12.7.11.240.545
2y9qANPMitogen-activated protein kinase 12.7.11.240.538
4fv4EK7Mitogen-activated protein kinase 12.7.11.240.537
4bcoT6QCyclin-dependent kinase 22.7.11.220.524
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.523
4fv6E57Mitogen-activated protein kinase 12.7.11.240.521
2oji33AMitogen-activated protein kinase 12.7.11.240.520
1h1q2A6Cyclin-dependent kinase 22.7.11.220.517
4g6oE28Mitogen-activated protein kinase 12.7.11.240.517
3r7uX96Cyclin-dependent kinase 22.7.11.220.516
2c4g514Cyclin-dependent kinase 22.7.11.220.515
3rm618ZCyclin-dependent kinase 22.7.11.220.515
3ddpRC8Cyclin-dependent kinase 22.7.11.220.512
3r7iX9ICyclin-dependent kinase 22.7.11.220.512
3lfqA28Cyclin-dependent kinase 22.7.11.220.511
4nj32KDCyclin-dependent kinase 22.7.11.220.511
1b39ATPCyclin-dependent kinase 22.7.11.220.510
2uzeC95Cyclin-dependent kinase 22.7.11.220.510
1e9hINRCyclin-dependent kinase 22.7.11.220.509
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.509
2z7lS91Mitogen-activated protein kinase 12.7.11.240.509
3qx4X4BCyclin-dependent kinase 22.7.11.220.509
4fkj11KCyclin-dependent kinase 22.7.11.220.509
1eh4IC1Casein kinase I homolog 12.7.11.10.508
2w06FRVCyclin-dependent kinase 22.7.11.220.507
4fkt48KCyclin-dependent kinase 22.7.11.220.506
3fz1B98Cyclin-dependent kinase 22.7.11.220.504
4bcpT3CCyclin-dependent kinase 22.7.11.220.504
3qzhX69Cyclin-dependent kinase 22.7.11.220.503
4ckiADNProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.503
4g6nEK0Mitogen-activated protein kinase 12.7.11.240.503
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.502
4bcqTJFCyclin-dependent kinase 22.7.11.220.502
4fmqANPMitogen-activated protein kinase 12.7.11.240.502
2vtnLZ7Cyclin-dependent kinase 22.7.11.220.501
2x1nX1NCyclin-dependent kinase 22.7.11.220.501
1aq1STUCyclin-dependent kinase 22.7.11.220.500
2a0cCK9Cyclin-dependent kinase 22.7.11.220.499
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.499
3rni21ZCyclin-dependent kinase 22.7.11.220.499
1w0xOLOCyclin-dependent kinase 22.7.11.220.498
3qwjX6ACyclin-dependent kinase 22.7.11.220.498
3qyzZ8BMitogen-activated protein kinase 12.7.11.240.498
3sa0NRAMitogen-activated protein kinase 12.7.11.240.498
3tnwF18Cyclin-dependent kinase 22.7.11.220.498
4gfg0XFTyrosine-protein kinase SYK2.7.10.20.498
4yuqKS1Calmodulin-like domain protein kinase/0.498
1tvoFRZMitogen-activated protein kinase 12.7.11.240.497
2r3gSC9Cyclin-dependent kinase 22.7.11.220.497
3n8nN883-dehydroquinate dehydratase4.2.1.100.497
3qyw6PBMitogen-activated protein kinase 12.7.11.240.497
3rpo24ZCyclin-dependent kinase 22.7.11.220.497
4n0sDHCMitogen-activated protein kinase 12.7.11.240.497
5aniES4Cyclin-dependent kinase 22.7.11.220.497
2r3fSC8Cyclin-dependent kinase 22.7.11.220.496
1oiyN41Cyclin-dependent kinase 22.7.11.220.495
1pxpCK8Cyclin-dependent kinase 22.7.11.220.495
1vyzN5BCyclin-dependent kinase 22.7.11.220.495
4eok4SPCyclin-dependent kinase 22.7.11.220.495
4fkpLS5Cyclin-dependent kinase 22.7.11.220.495
1oiuN76Cyclin-dependent kinase 22.7.11.220.494
3i60E86Mitogen-activated protein kinase 12.7.11.240.494
3qqlX03Cyclin-dependent kinase 22.7.11.220.494
3r7yZ04Cyclin-dependent kinase 22.7.11.220.494
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.493
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.493
2wpa889Cyclin-dependent kinase 22.7.11.220.492
3pe2E1BCasein kinase II subunit alpha2.7.11.10.492
4fyo0VFTyrosine-protein kinase SYK2.7.10.20.492
4xgxADPFAD:protein FMN transferase/0.492
3qqhX0ACyclin-dependent kinase 22.7.11.220.491
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.491
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.490
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.490
4fv1EK4Mitogen-activated protein kinase 12.7.11.240.490
4i0s1B5Tyrosine-protein kinase SYK2.7.10.20.490
2b9fADPMitogen-activated protein kinase FUS32.7.11.240.489
2c5nCK8Cyclin-dependent kinase 22.7.11.220.489
3hztJ60Calmodulin-like domain protein kinase isoform 3/0.489
3mvl38PMitogen-activated protein kinase 14/0.489
4ek610KCyclin-dependent kinase 22.7.11.220.489
4fki09KCyclin-dependent kinase 22.7.11.220.489
4jrnANPRhoptry kinase family protein/0.489
1g5sI17Cyclin-dependent kinase 22.7.11.220.488
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.488
2hog710Serine/threonine-protein kinase Chk12.7.11.10.488
3bqr4RBDeath-associated protein kinase 3/0.488
1b38ATPCyclin-dependent kinase 22.7.11.220.487
3qx2X63Cyclin-dependent kinase 22.7.11.220.487
3sheI85MAP kinase-activated protein kinase 32.7.11.10.487
4f4p0SBTyrosine-protein kinase SYK2.7.10.20.487
4fv5EK9Mitogen-activated protein kinase 12.7.11.240.487
2vtqLZACyclin-dependent kinase 22.7.11.220.486
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.486
3ddqRRCCyclin-dependent kinase 22.7.11.220.486
3roy22ZCyclin-dependent kinase 22.7.11.220.486
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.486
3emg685Tyrosine-protein kinase SYK2.7.10.20.485
3pxkPXKFocal adhesion kinase 12.7.10.20.485
3r7vZ02Cyclin-dependent kinase 22.7.11.220.485
3w551FMMitogen-activated protein kinase 12.7.11.240.485
4eor4SPCyclin-dependent kinase 22.7.11.220.485
3ezrEZRCyclin-dependent kinase 22.7.11.220.484
4fklCK2Cyclin-dependent kinase 22.7.11.220.484
2b55D31Cyclin-dependent kinase 22.7.11.220.483
2btsU32Cyclin-dependent kinase 22.7.11.220.483
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.482
4bcnT9NCyclin-dependent kinase 22.7.11.220.482
4fv3EK6Mitogen-activated protein kinase 12.7.11.240.482
4fz70VHTyrosine-protein kinase SYK2.7.10.20.482
1uv5BRWGlycogen synthase kinase-3 beta2.7.11.260.481
3qziX72Cyclin-dependent kinase 22.7.11.220.481
3rvg17PTyrosine-protein kinase JAK2/0.481
4a9uA9USerine/threonine-protein kinase Chk22.7.11.10.481
1dm2HMDCyclin-dependent kinase 22.7.11.220.480
1h0vUN4Cyclin-dependent kinase 22.7.11.220.480
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.480
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.480
3r1qX75Cyclin-dependent kinase 22.7.11.220.480
4ct2ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.480
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.480
1pyePM1Cyclin-dependent kinase 22.7.11.220.479
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.479
2r3p3SCCyclin-dependent kinase 22.7.11.220.479
2wtiWTISerine/threonine-protein kinase Chk22.7.11.10.479
3r83Z14Cyclin-dependent kinase 22.7.11.220.479
3zh8C58Protein kinase C iota type2.7.11.130.479
4btjADPTau-tubulin kinase 12.7.11.10.479
1pxoCK7Cyclin-dependent kinase 22.7.11.220.478
1q1rFADPutidaredoxin reductase1.18.1.50.478
2btrU73Cyclin-dependent kinase 22.7.11.220.478
2iw6QQ2Cyclin-dependent kinase 22.7.11.220.478
2uzoC62Cyclin-dependent kinase 22.7.11.220.478
2vu3LZECyclin-dependent kinase 22.7.11.220.478
4b7tCWTGlycogen synthase kinase-3 beta2.7.11.260.478
4gub0Y4Casein kinase II subunit alpha2.7.11.10.478
1tqpATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.477
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.477
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.477
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.477
2pvmP29Casein kinase II subunit alpha2.7.11.10.477
3qxoX65Cyclin-dependent kinase 22.7.11.220.477
3s2pPMUCyclin-dependent kinase 22.7.11.220.477
4ewhT77Activated CDC42 kinase 1/0.477
4mf029ZTyrosine-protein kinase ITK/TSK2.7.10.20.477
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.476
1unlRRCCyclin-dependent-like kinase 52.7.11.10.476
2wtjWTJSerine/threonine-protein kinase Chk22.7.11.10.476
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.476
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.476
1ckpPVBCyclin-dependent kinase 22.7.11.220.475
2dwbANPAurora kinase A2.7.11.10.475
2iw84SPCyclin-dependent kinase 22.7.11.220.475
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.475
3qrtX14Cyclin-dependent kinase 22.7.11.220.475
3r6xX84Cyclin-dependent kinase 22.7.11.220.475
4dfl0K0Tyrosine-protein kinase SYK2.7.10.20.475
5dr6SKEAurora kinase A2.7.11.10.475
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.474
2r64740Cyclin-dependent kinase 22.7.11.220.474
3f7z34OGlycogen synthase kinase-3 beta2.7.11.260.474
3rjc06ZCyclin-dependent kinase 22.7.11.220.474
4fuxE75Mitogen-activated protein kinase 12.7.11.240.474
2a4lRRCCyclin-dependent kinase 22.7.11.220.473
2c6o4SPCyclin-dependent kinase 22.7.11.220.473
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.473
3lfnA27Cyclin-dependent kinase 22.7.11.220.473
3nynSGVG protein-coupled receptor kinase 62.7.11.160.473
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.473
1zaoATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.472
2i40BLZCyclin-dependent kinase 22.7.11.220.472
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.472
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.472
2xa4AZ5Tyrosine-protein kinase JAK2/0.472
3gubGUBDeath-associated protein kinase 12.7.11.10.472
3qqfX07Cyclin-dependent kinase 22.7.11.220.472
3r1sX73Cyclin-dependent kinase 22.7.11.220.472
3rm719ZCyclin-dependent kinase 22.7.11.220.472
4ft3H1KSerine/threonine-protein kinase Chk12.7.11.10.472
4fv0EK3Mitogen-activated protein kinase 12.7.11.240.472
4qnaX11Serine/threonine-protein kinase 242.7.11.10.472
1h1s4SPCyclin-dependent kinase 22.7.11.220.471
1q5kTMUGlycogen synthase kinase-3 beta2.7.11.260.471
2bkzSBCCyclin-dependent kinase 22.7.11.220.471
2iw94SPCyclin-dependent kinase 22.7.11.220.471
2vtlLZ5Cyclin-dependent kinase 22.7.11.220.471
4jq8KJ8Epidermal growth factor receptor2.7.10.10.471
1xjdSTUProtein kinase C theta type2.7.11.130.470
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.470
2itnANPEpidermal growth factor receptor2.7.10.10.470
2xmyCDKCyclin-dependent kinase 22.7.11.220.470
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.470
4i22IREEpidermal growth factor receptor2.7.10.10.470
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.470
4yswFADXanthine dehydrogenase/oxidase/0.470
1h1r6CPCyclin-dependent kinase 22.7.11.220.469
1ke7LS3Cyclin-dependent kinase 22.7.11.220.469
1oirHDYCyclin-dependent kinase 22.7.11.220.469
2b53D23Cyclin-dependent kinase 22.7.11.220.469
2pe039Z3-phosphoinositide-dependent protein kinase 12.7.11.10.469
2r3r6SCCyclin-dependent kinase 22.7.11.220.469
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.469
2xb7GUIALK tyrosine kinase receptor2.7.10.10.469
3q3b55EGlycogen synthase kinase-3 beta2.7.11.260.469
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.469
4c02TAKActivin receptor type-12.7.11.300.469
1oitHDTCyclin-dependent kinase 22.7.11.220.468
3ig7EFPCyclin-dependent kinase 22.7.11.220.468
3r1yX76Cyclin-dependent kinase 22.7.11.220.468
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.468
3vf9477Tyrosine-protein kinase SYK2.7.10.20.468
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.468
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.468
4fv2EK5Mitogen-activated protein kinase 12.7.11.240.468
3ql8X01Cyclin-dependent kinase 22.7.11.220.467
4an92P7Dual specificity mitogen-activated protein kinase kinase 12.7.12.20.467
4bgh3I6Cyclin-dependent kinase 22.7.11.220.467
4eol1ROCyclin-dependent kinase 22.7.11.220.467
4rqvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.467
4wboANWRhodopsin kinase/0.467
1oi9N20Cyclin-dependent kinase 22.7.11.220.466
1pxlCK4Cyclin-dependent kinase 22.7.11.220.466
1uu9BI33-phosphoinositide-dependent protein kinase 12.7.11.10.466
1vyw292Cyclin-dependent kinase 22.7.11.220.466
2j9mPY8Cyclin-dependent kinase 22.7.11.220.466
2r3mSCXCyclin-dependent kinase 22.7.11.220.466
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.466
2y7jB49Phosphorylase b kinase gamma catalytic chain, liver/testis isoform2.7.11.190.466
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.466
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.466
3okxSAMS-adenosyl-L-methionine-binding protein RPA0152/0.466
3qu0X40Cyclin-dependent kinase 22.7.11.220.466
4fsmHK1Serine/threonine-protein kinase Chk12.7.11.10.466
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.466
5e8xSTUTGF-beta receptor type-12.7.11.300.466
2c6iDT1Cyclin-dependent kinase 22.7.11.220.465
2wotZZGTGF-beta receptor type-12.7.11.300.465
4bdaVFBSerine/threonine-protein kinase Chk22.7.11.10.465
4fkg4CKCyclin-dependent kinase 22.7.11.220.465
4kiq1RAMitogen-activated protein kinase 14/0.465
2c68CT6Cyclin-dependent kinase 22.7.11.220.464
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.464
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.464
2j0lANPFocal adhesion kinase 12.7.10.20.464
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.464
3lfsA07Cyclin-dependent kinase 22.7.11.220.464
3rak03ZCyclin-dependent kinase 22.7.11.220.464
4bdhWVISerine/threonine-protein kinase Chk22.7.11.10.464
4fyn0VETyrosine-protein kinase SYK2.7.10.20.464
1oguST8Cyclin-dependent kinase 22.7.11.220.463
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.463
2csnCKICasein kinase I homolog 12.7.11.10.463
2wouZZFTGF-beta receptor type-12.7.11.300.463
4fks46KCyclin-dependent kinase 22.7.11.220.463
4fuyEK2Mitogen-activated protein kinase 12.7.11.240.463
4jajXU1Aurora kinase A2.7.11.10.463
4loqSB4Mitogen-activated protein kinase 14/0.463
1phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.462
1zys199Serine/threonine-protein kinase Chk12.7.11.10.462
2e9p77ASerine/threonine-protein kinase Chk12.7.11.10.462
2r3lSCWCyclin-dependent kinase 22.7.11.220.462
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.462
2xikJ60Serine/threonine-protein kinase 252.7.11.10.462
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.462
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.461
2ojj82AMitogen-activated protein kinase 12.7.11.240.461
2r3jSCJCyclin-dependent kinase 22.7.11.220.461
3rkb12ZCyclin-dependent kinase 22.7.11.220.461
3sqq99ZCyclin-dependent kinase 22.7.11.220.461
4erkOLOMitogen-activated protein kinase 12.7.11.240.461
4fx360KCyclin-dependent kinase 22.7.11.220.461
1e1xNW1Cyclin-dependent kinase 22.7.11.220.460
1urwI1PCyclin-dependent kinase 22.7.11.220.460
2ojg19AMitogen-activated protein kinase 12.7.11.240.460
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.460
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.460
3q9xEMOCasein kinase II subunit alpha2.7.11.10.460
3r8pZ46Cyclin-dependent kinase 22.7.11.220.460
3tqhNDPQuinone oxidoreductase/0.460
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.460
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.460
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.460
4fkr45KCyclin-dependent kinase 22.7.11.220.460
4fkv61KCyclin-dependent kinase 22.7.11.220.460
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.460
4ftjH8KSerine/threonine-protein kinase Chk12.7.11.10.460
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.460
1pxkCK3Cyclin-dependent kinase 22.7.11.220.459
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.459
3gu6ADPDeath-associated protein kinase 12.7.11.10.459
3lctADPALK tyrosine kinase receptor2.7.10.10.459
3r7eX88Cyclin-dependent kinase 22.7.11.220.459
4bdfH3RSerine/threonine-protein kinase Chk22.7.11.10.459
1gij2PUCyclin-dependent kinase 22.7.11.220.458
1mq4ADPAurora kinase A2.7.11.10.458
2r3kSCQCyclin-dependent kinase 22.7.11.220.458
3ezvEZVCyclin-dependent kinase 22.7.11.220.458
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.458
3unk0BYCyclin-dependent kinase 22.7.11.220.458
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.458
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.458
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.458
1pxmCK5Cyclin-dependent kinase 22.7.11.220.457
2itzIREEpidermal growth factor receptor2.7.10.10.457
2wtkANPSTE20-related kinase adapter protein alpha/0.457
2zjwREFCasein kinase II subunit alpha2.7.11.10.457
3bhtMFRCyclin-dependent kinase 22.7.11.220.457
3buzLARActin, alpha skeletal muscle/0.457
3dogNNNCyclin-dependent kinase 22.7.11.220.457
3fzr3JZProtein-tyrosine kinase 2-beta2.7.10.20.457
3le62BZCyclin-dependent kinase 22.7.11.220.457
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.457
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.457
4deaNHIAurora kinase A2.7.11.10.457
1di8DTQCyclin-dependent kinase 22.7.11.220.456
1h1pCMGCyclin-dependent kinase 22.7.11.220.456
1vjy460TGF-beta receptor type-12.7.11.300.456
2c6tDT5Cyclin-dependent kinase 22.7.11.220.456
2duv371Cyclin-dependent kinase 22.7.11.220.456
2exmZIPCyclin-dependent kinase 22.7.11.220.456
2fumMIXSerine/threonine-protein kinase PknB2.7.11.10.456
2pwlACPFibroblast growth factor receptor 2/0.456
3pj8404Cyclin-dependent kinase 22.7.11.220.456
3qqkX02Cyclin-dependent kinase 22.7.11.220.456
3r28XA0Cyclin-dependent kinase 22.7.11.220.456
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.456
3zm422TDual specificity mitogen-activated protein kinase kinase 12.7.12.20.456
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.456
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.456
4fsyHK7Serine/threonine-protein kinase Chk12.7.11.10.456
4g170VNCasein kinase I isoform gamma-32.7.11.10.456
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.456
4ii5ADPCyclin-dependent kinase 22.7.11.220.456
1gz8MBPCyclin-dependent kinase 22.7.11.220.455
1p2a5BNCyclin-dependent kinase 22.7.11.220.455
1py5PY1TGF-beta receptor type-12.7.11.300.455
1ykr628Cyclin-dependent kinase 22.7.11.220.455
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.455
2bdjHETProto-oncogene tyrosine-protein kinase Src2.7.10.20.455
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.455
3c50ADPRhodopsin kinase/0.455
3du8553Glycogen synthase kinase-3 beta2.7.11.260.455
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.455
4b8lA0PAurora kinase B-A2.7.11.10.455
4cfnJYMCyclin-dependent kinase 22.7.11.220.455
4mq12C3Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.455
5e92ANPTGF-beta receptor type-22.7.11.300.455
1k6pXN3Gag-Pol polyprotein3.4.23.160.454
1ke6LS2Cyclin-dependent kinase 22.7.11.220.454
1pmeSB2Mitogen-activated protein kinase 12.7.11.240.454
1v1k3FPCyclin-dependent kinase 22.7.11.220.454
2evaADNMitogen-activated protein kinase kinase kinase 72.7.11.250.454
4xfjANPArgininosuccinate synthase/0.454
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.453
2h96893Mitogen-activated protein kinase 82.7.11.240.453
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.453
2w05FRTCyclin-dependent kinase 22.7.11.220.453
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.453
3dtcVINMitogen-activated protein kinase kinase kinase 92.7.11.250.453
3my5RFZCyclin-dependent kinase 22.7.11.220.453
3nga3NGCasein kinase II subunit alpha2.7.11.10.453
3q43D66M1 family aminopeptidase3.4.110.453
3r73X87Cyclin-dependent kinase 22.7.11.220.453
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.453
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.453
4aacAAVMitogen-activated protein kinase 14/0.453
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.453
4yhjAN2G protein-coupled receptor kinase 42.7.11.160.453
1nuqNXXNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.452
1nxkSTUMAP kinase-activated protein kinase 22.7.11.10.452
1z5mLI83-phosphoinositide-dependent protein kinase 12.7.11.10.452
2c5yMTWCyclin-dependent kinase 22.7.11.220.452
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.452
2ijmADPFocal adhesion kinase 12.7.10.20.452
3a62STURibosomal protein S6 kinase beta-12.7.11.10.452
3bhy7CPDeath-associated protein kinase 3/0.452
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.452
3qwkX62Cyclin-dependent kinase 22.7.11.220.452
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.452
4acdGR9Glycogen synthase kinase-3 beta2.7.11.260.452
4zohFADPutative oxidoreductase FAD-binding subunit/0.452
1gih1PUCyclin-dependent kinase 22.7.11.220.451
1h0w207Cyclin-dependent kinase 22.7.11.220.451
1ke5LS1Cyclin-dependent kinase 22.7.11.220.451
2j7t274Serine/threonine-protein kinase 102.7.11.10.451
2r3iSCFCyclin-dependent kinase 22.7.11.220.451
2r3wG3GGag-Pol polyprotein3.4.23.160.451
2x2lX2LProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.451
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.451
2zoq5IDMitogen-activated protein kinase 32.7.11.240.451
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.451
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.451
3t8oATPRhodopsin kinase/0.451
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.451
4zseANPEpidermal growth factor receptor2.7.10.10.451
1m2rMNYCasein kinase II subunit alpha2.7.11.10.450
1xelUPGUDP-glucose 4-epimerase5.1.3.20.450
2ijmATPFocal adhesion kinase 12.7.10.20.450
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.450
3rpv26ZCyclin-dependent kinase 22.7.11.220.450
3tiz3TICyclin-dependent kinase 22.7.11.220.450
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.450
4grb0XGCasein kinase II subunit alpha2.7.11.10.450
5aacVGHALK tyrosine kinase receptor2.7.10.10.450
1ke8LS4Cyclin-dependent kinase 22.7.11.220.449
1m2qMNXCasein kinase II subunit alpha2.7.11.10.449
2bheBRYCyclin-dependent kinase 22.7.11.220.449
2bhhRYUCyclin-dependent kinase 22.7.11.220.449
2uzlC94Cyclin-dependent kinase 22.7.11.220.449
2x7gPVBSRSF protein kinase 22.7.11.10.449
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.449
3nuuJOZ3-phosphoinositide-dependent protein kinase 12.7.11.10.449
3nwq2NCGag-Pol polyprotein3.4.23.160.449
3qd33Q53-phosphoinositide-dependent protein kinase 12.7.11.10.449
3ral04ZCyclin-dependent kinase 22.7.11.220.449
3s2a2NQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
3vf80JETyrosine-protein kinase SYK2.7.10.20.449
4ek816KCyclin-dependent kinase 22.7.11.220.449
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.449
4o0wADNAurora kinase A2.7.11.10.449
5auuLU2Death-associated protein kinase 12.7.11.10.449
1fvt106Cyclin-dependent kinase 22.7.11.220.448
1kvtUPGUDP-glucose 4-epimerase5.1.3.20.448
1zarADPRIO-type serine/threonine-protein kinase Rio22.7.11.10.448
2b9iADPMitogen-activated protein kinase FUS32.7.11.240.448
2b9jADPMitogen-activated protein kinase FUS32.7.11.240.448
2f2cAP9Cyclin-dependent kinase 62.7.11.220.448
2gr1FADFerredoxin reductase/0.448
2pziAXXSerine/threonine-protein kinase PknG2.7.11.10.448
2wmtZYTSerine/threonine-protein kinase Chk12.7.11.10.448
2ydkYDKSerine/threonine-protein kinase Chk12.7.11.10.448
3et7349Protein-tyrosine kinase 2-beta2.7.10.20.448
3pxyJWSCyclin-dependent kinase 22.7.11.220.448
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.448
3ti1B49Cyclin-dependent kinase 22.7.11.220.448
4e93GUITyrosine-protein kinase Fes/Fps2.7.10.20.448
4eon1ROCyclin-dependent kinase 22.7.11.220.448
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.448
4hgl0YOCasein kinase I isoform gamma-32.7.11.10.448
4k8aK8AFocal adhesion kinase 12.7.10.20.448
4lopSB4Mitogen-activated protein kinase 14/0.448
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
1w8cN69Cyclin-dependent kinase 22.7.11.220.447
2c6mDT5Cyclin-dependent kinase 22.7.11.220.447
2cchATPCyclin-dependent kinase 22.7.11.220.447
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.447
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.447
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.447
3rk708ZCyclin-dependent kinase 22.7.11.220.447
4fko20KCyclin-dependent kinase 22.7.11.220.447
4o0sADNAurora kinase A2.7.11.10.447
4y93746Tyrosine-protein kinase/0.447
5c03AGSNon-receptor tyrosine-protein kinase TYK22.7.10.20.447
1kkq471Peroxisome proliferator-activated receptor alpha/0.446
1uu7BI23-phosphoinositide-dependent protein kinase 12.7.11.10.446
1y8yCT7Cyclin-dependent kinase 22.7.11.220.446
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.446
3qtzX42Cyclin-dependent kinase 22.7.11.220.446
3rpy27ZCyclin-dependent kinase 22.7.11.220.446
3sw418KCyclin-dependent kinase 22.7.11.220.446
3v8t477Tyrosine-protein kinase ITK/TSK2.7.10.20.446
4a9tA9TSerine/threonine-protein kinase Chk22.7.11.10.446
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.446
4c61LMMTyrosine-protein kinase JAK2/0.446
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.446
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.446
1v0pPVBCell division control protein 2 homolog2.7.11.220.445
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.445
2ittAEEEpidermal growth factor receptor2.7.10.10.445
2q6bHR23-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.340.445
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.445
2qkrIXMCdc2-like CDK2/CDC28 like protein kinase/0.445
3h9f92MDual specificity protein kinase TTK2.7.12.10.445
3iggEFQCyclin-dependent kinase 22.7.11.220.445
3igoANPCalmodulin-domain protein kinase 1, putative/0.445
3rmf20ZCyclin-dependent kinase 22.7.11.220.445
3tucFPWTyrosine-protein kinase SYK2.7.10.20.445
3vs4VSFTyrosine-protein kinase HCK2.7.10.20.445
3vs6VSHTyrosine-protein kinase HCK2.7.10.20.445
3w0nANPHygromycin-B 4-O-kinase2.7.1.1630.445
3zewSTUEphrin type-B receptor 42.7.10.10.445
3zls92PDual specificity mitogen-activated protein kinase kinase 12.7.12.20.445
3zmmF9JTyrosine-protein kinase JAK2/0.445
4eos1ROCyclin-dependent kinase 22.7.11.220.445
4fkq42KCyclin-dependent kinase 22.7.11.220.445
4j711JXGlycogen synthase kinase-3 beta2.7.11.260.445
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.445
1t86CAMCamphor 5-monooxygenase1.14.15.10.444
2bsmBSMHeat shock protein HSP 90-alpha/0.444
2c6lDT4Cyclin-dependent kinase 22.7.11.220.444
2vttLZDCyclin-dependent kinase 22.7.11.220.444
2wihP48Cyclin-dependent kinase 22.7.11.220.444
2zaxCAMCamphor 5-monooxygenase1.14.15.10.444
3lmgANPReceptor tyrosine-protein kinase erbB-32.7.10.10.444
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.444
3uo50BXAurora kinase A2.7.11.10.444
3zze6XPHepatocyte growth factor receptor2.7.10.10.444
4bdgP3JSerine/threonine-protein kinase Chk22.7.11.10.444
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.444
4fob0USALK tyrosine kinase receptor2.7.10.10.444
4kbk1QGCasein kinase I isoform delta2.7.11.10.444
4l521ULMitogen-activated protein kinase kinase kinase 72.7.11.250.444
1a9yUPGUDP-glucose 4-epimerase5.1.3.20.443
1bwfATFGlycerol kinase/0.443
1bxoPP7Penicillopepsin-13.4.23.200.443
1jvsNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.443
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.443
1q4l679Glycogen synthase kinase-3 beta2.7.11.260.443
1vrqFMNSubunit alpha of sarocosine oxidase/0.443
1vrqFMNSubunit beta of sarcosine oxidase/0.443
1wvySTUDeath-associated protein kinase 12.7.11.10.443
1xkkFMMEpidermal growth factor receptor2.7.10.10.443
2b52D42Cyclin-dependent kinase 22.7.11.220.443
2c6kDT2Cyclin-dependent kinase 22.7.11.220.443
2izuP01Casein kinase I isoform gamma-32.7.11.10.443
2pvnP63Casein kinase II subunit alpha2.7.11.10.443
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.443
3l1sZ92Glycogen synthase kinase-3 beta2.7.11.260.443
3nwxKVSGag-Pol polyprotein3.4.23.160.443
3rk507ZCyclin-dependent kinase 22.7.11.220.443
3w0rANPHygromycin-B 4-O-kinase2.7.1.1630.443
4dgo0JWCasein kinase II subunit alpha2.7.11.10.443
4gu610NFocal adhesion kinase 12.7.10.20.443
4kb81QNCasein kinase I isoform delta2.7.11.10.443
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.443
5cshATPCasein kinase II subunit alpha2.7.11.10.443
1mruAGSSerine/threonine-protein kinase PknB2.7.11.10.442
1qmfKEFPenicillin-binding protein 2x/0.442
2xp2VGHALK tyrosine kinase receptor2.7.10.10.442
2zdu446Mitogen-activated protein kinase 102.7.11.240.442
3gb2G3BGlycogen synthase kinase-3 beta2.7.11.260.442
3qtrX36Cyclin-dependent kinase 22.7.11.220.442
4aguD15Cyclin-dependent kinase-like 1/0.442
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.442
4fad0TBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
4hnf16WCasein kinase I isoform delta2.7.11.10.442
4i4e1BQFocal adhesion kinase 12.7.10.20.442
4im01FVSerine/threonine-protein kinase TBK12.7.11.10.442
4jhz1KVBeta-glucuronidase3.2.1.310.442
4lyn1YGCyclin-dependent kinase 22.7.11.220.442
4qmySTUSerine/threonine-protein kinase 242.7.11.10.442
5kgpACOPredicted acetyltransferase/0.442
1gy3ATPCyclin-dependent kinase 22.7.11.220.441
1m17AQ4Epidermal growth factor receptor2.7.10.10.441
2jkqVG8Focal adhesion kinase 12.7.10.20.441
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.441
3be9P04Casein kinase II subunit alpha2.7.11.10.441
3eljGS7Mitogen-activated protein kinase 82.7.11.240.441
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.441
3qtuX44Cyclin-dependent kinase 22.7.11.220.441
3r9dX6BCyclin-dependent kinase 22.7.11.220.441
3rahO1ZCyclin-dependent kinase 22.7.11.220.441
3w0sANPHygromycin-B 4-O-kinase2.7.1.1630.441
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
4gk3L87Ephrin type-A receptor 32.7.10.10.441
4hge15VTyrosine-protein kinase JAK2/0.441
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.441
4j6i1JVPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.441
4kz01UJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
1e8zSTUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
1odw0E8Gag-Pol polyprotein3.4.23.160.440
1u5rATPSerine/threonine-protein kinase TAO22.7.11.10.440
2itqITQEpidermal growth factor receptor2.7.10.10.440
2pvlP55Casein kinase II subunit alpha2.7.11.10.440
2uzbC75Cyclin-dependent kinase 22.7.11.220.440
2vthLZ2Cyclin-dependent kinase 22.7.11.220.440
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.440
2ye42FYHeat shock protein HSP 90-alpha/0.440
3cgcFADCoenzyme A disulfide reductase/0.440
3lxiCAMCytochrome P450/0.440
3nlb5BESerine/threonine-protein kinase Chk12.7.11.10.440
3qzgX67Cyclin-dependent kinase 22.7.11.220.440
3r71X86Cyclin-dependent kinase 22.7.11.220.440
3r8lZ30Cyclin-dependent kinase 22.7.11.220.440
4dgmAGICasein kinase II subunit alpha2.7.11.10.440
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.440
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.440
4ktc1X3Genome polyprotein3.4.21.980.440
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.440