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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4deaNHIAurora kinase A2.7.11.1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4deaNHIAurora kinase A2.7.11.11.000
3k5uPFQAurora kinase A2.7.11.10.680
4jajXU1Aurora kinase A2.7.11.10.665
3uo50BXAurora kinase A2.7.11.10.664
5dr6SKEAurora kinase A2.7.11.10.628
2dwbANPAurora kinase A2.7.11.10.616
2xru400Aurora kinase A2.7.11.10.605
5dpvSKEAurora kinase A2.7.11.10.600
5drdATPAurora kinase A2.7.11.10.599
4o0wADNAurora kinase A2.7.11.10.597
2np8CC3Aurora kinase A2.7.11.10.594
2w1fL0FAurora kinase A2.7.11.10.584
5dt0SKEAurora kinase A2.7.11.10.582
4c3rACPAurora kinase A2.7.11.10.579
2w1gL0GAurora kinase A2.7.11.10.574
4jbpYPHAurora kinase A2.7.11.10.569
2x6dX6DAurora kinase A2.7.11.10.568
2w1dL0DAurora kinase A2.7.11.10.567
5dr2ATPAurora kinase A2.7.11.10.563
1mq4ADPAurora kinase A2.7.11.10.559
3w16P9JAurora kinase A2.7.11.10.557
5dr9SKEAurora kinase A2.7.11.10.555
5dn3ATPAurora kinase A2.7.11.10.554
5dosATPAurora kinase A2.7.11.10.548
5dt4ATPAurora kinase A2.7.11.10.540
1ol7ADPAurora kinase A2.7.11.10.539
2w1eL0EAurora kinase A2.7.11.10.530
5dt3ATPAurora kinase A2.7.11.10.528
2xngA0HAurora kinase A2.7.11.10.525
4o0sADNAurora kinase A2.7.11.10.520
1ol5ADPAurora kinase A2.7.11.10.516
5dnrATPAurora kinase A2.7.11.10.515
4jbqVX6Aurora kinase A2.7.11.10.513
4wboANWRhodopsin kinase/0.513
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.511
3t8oATPRhodopsin kinase/0.508
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.506
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.506
1q5kTMUGlycogen synthase kinase-3 beta2.7.11.260.505
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.505
4deeADPAurora kinase A2.7.11.10.503
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.502
3sheI85MAP kinase-activated protein kinase 32.7.11.10.502
1h0w207Cyclin-dependent kinase 22.7.11.220.498
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.498
4gmy0X5Tyrosine-protein kinase JAK2/0.498
2x1nX1NCyclin-dependent kinase 22.7.11.220.497
4ct2ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.497
4dgo0JWCasein kinase II subunit alpha2.7.11.10.497
2j9mPY8Cyclin-dependent kinase 22.7.11.220.496
4k8aK8AFocal adhesion kinase 12.7.10.20.496
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.495
4mq12C3Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.495
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.494
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.493
4c3pACPAurora kinase A2.7.11.10.493
1h1r6CPCyclin-dependent kinase 22.7.11.220.492
3iok1P6Tyrosine-protein kinase JAK2/0.492
4l3l5FIRibosomal protein S6 kinase beta-12.7.11.10.492
2xneASHAurora kinase A2.7.11.10.491
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.491
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.491
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.490
2r3o2SCCyclin-dependent kinase 22.7.11.220.490
2ijmATPFocal adhesion kinase 12.7.10.20.489
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.489
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.489
1uv5BRWGlycogen synthase kinase-3 beta2.7.11.260.488
3pxkPXKFocal adhesion kinase 12.7.10.20.488
3v5j0F2Tyrosine-protein kinase ITK/TSK2.7.10.20.485
1di8DTQCyclin-dependent kinase 22.7.11.220.483
3lfqA28Cyclin-dependent kinase 22.7.11.220.483
5cshATPCasein kinase II subunit alpha2.7.11.10.483
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.482
3at3ATKCasein kinase II subunit alpha2.7.11.10.482
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.482
3at4CCKCasein kinase II subunit alpha2.7.11.10.481
3ezrEZRCyclin-dependent kinase 22.7.11.220.481
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.481
3q9xEMOCasein kinase II subunit alpha2.7.11.10.481
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.481
4ek816KCyclin-dependent kinase 22.7.11.220.481
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.481
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.480
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.480
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.480
4jboWPHAurora kinase A2.7.11.10.480
4jia1K3Tyrosine-protein kinase JAK2/0.480
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.479
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.479
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.479
5l8lADPAurora kinase A2.7.11.10.479
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.478
1oguST8Cyclin-dependent kinase 22.7.11.220.478
4c57FEFCyclin-G-associated kinase2.7.11.10.478
3mfrANPPeripheral plasma membrane protein CASK2.7.11.10.477
3oibFDAPutative acyl-CoA dehydrogenase/0.477
4ckiADNProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.477
4l3j5FIRibosomal protein S6 kinase beta-12.7.11.10.477
4utdACPAurora kinase A2.7.11.10.477
5dmzADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.477
2ijmADPFocal adhesion kinase 12.7.10.20.476
2jkqVG8Focal adhesion kinase 12.7.10.20.476
1bygSTUTyrosine-protein kinase CSK/0.475
1m2rMNYCasein kinase II subunit alpha2.7.11.10.475
2yn8STUEphrin type-B receptor 42.7.10.10.475
3a62STURibosomal protein S6 kinase beta-12.7.11.10.475
3be9P04Casein kinase II subunit alpha2.7.11.10.475
3eljGS7Mitogen-activated protein kinase 82.7.11.240.475
3r9hZ67Cyclin-dependent kinase 22.7.11.220.475
4fjyFJYPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.475
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.475
4o0uADNAurora kinase A2.7.11.10.475
4r8qADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.475
3ddpRC8Cyclin-dependent kinase 22.7.11.220.474
4fv6E57Mitogen-activated protein kinase 12.7.11.240.474
5auvAGIDeath-associated protein kinase 12.7.11.10.474
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.473
4eos1ROCyclin-dependent kinase 22.7.11.220.473
4mf029ZTyrosine-protein kinase ITK/TSK2.7.10.20.473
1h1s4SPCyclin-dependent kinase 22.7.11.220.472
2j0m4STFocal adhesion kinase 12.7.10.20.472
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.472
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.472
3fz1B98Cyclin-dependent kinase 22.7.11.220.472
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.472
3unj0BXCyclin-dependent kinase 22.7.11.220.472
4ewhT77Activated CDC42 kinase 1/0.472
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.472
4zohFADPutative oxidoreductase FAD-binding subunit/0.472
1e9hINRCyclin-dependent kinase 22.7.11.220.471
4bbe3O4Tyrosine-protein kinase JAK2/0.471
4bcnT9NCyclin-dependent kinase 22.7.11.220.471
4c58824Cyclin-G-associated kinase2.7.11.10.471
4i0r1B4Tyrosine-protein kinase SYK2.7.10.20.471
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.470
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.470
1xjdSTUProtein kinase C theta type2.7.11.130.470
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.470
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.470
2pe039Z3-phosphoinositide-dependent protein kinase 12.7.11.10.470
3c50ADPRhodopsin kinase/0.470
5auwQUEDeath-associated protein kinase 12.7.11.10.470
1dawANPCasein kinase II subunit alpha2.7.11.10.469
1lp4ANPCasein kinase II subunit alpha2.7.11.10.469
2pvhP19Casein kinase II subunit alpha2.7.11.10.469
3ggfGVDSerine/threonine-protein kinase 26/0.469
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.469
4im2BX7Serine/threonine-protein kinase TBK12.7.11.10.469
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.469
1ny3ADPMAP kinase-activated protein kinase 22.7.11.10.468
2excJNKMitogen-activated protein kinase 102.7.11.240.468
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.468
3emg685Tyrosine-protein kinase SYK2.7.10.20.468
3nwq2NCGag-Pol polyprotein3.4.23.160.468
3oroAGSSerine/threonine protein kinase/0.468
3rk507ZCyclin-dependent kinase 22.7.11.220.468
4bcoT6QCyclin-dependent kinase 22.7.11.220.468
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.468
4foc0UUALK tyrosine kinase receptor2.7.10.10.468
4k33ACPFibroblast growth factor receptor 32.7.10.10.468
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.468
1e1xNW1Cyclin-dependent kinase 22.7.11.220.467
2r64740Cyclin-dependent kinase 22.7.11.220.467
3u4uLNHCasein kinase II subunit alpha2.7.11.10.467
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.467
4b0gVEKAurora kinase A2.7.11.10.467
4b8lA0PAurora kinase B-A2.7.11.10.467
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.467
4eor4SPCyclin-dependent kinase 22.7.11.220.467
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.467
2h96893Mitogen-activated protein kinase 82.7.11.240.466
2iw84SPCyclin-dependent kinase 22.7.11.220.466
2v7a627Tyrosine-protein kinase ABL12.7.10.20.466
3l1sZ92Glycogen synthase kinase-3 beta2.7.11.260.466
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.466
4achKDIGlycogen synthase kinase-3 beta2.7.11.260.466
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.466
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.465
1z5mLI83-phosphoinositide-dependent protein kinase 12.7.11.10.465
2c6dANPAurora kinase A2.7.11.10.465
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.465
3efwAK8Aurora kinase A2.7.11.10.465
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.465
3r73X87Cyclin-dependent kinase 22.7.11.220.465
4anmWULCasein kinase II subunit alpha2.7.11.10.465
4fl1ANPTyrosine-protein kinase SYK2.7.10.20.465
4fyn0VETyrosine-protein kinase SYK2.7.10.20.465
1o6yACPSerine/threonine-protein kinase PknB2.7.11.10.464
1ol6ATPAurora kinase A2.7.11.10.464
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.464
2itqITQEpidermal growth factor receptor2.7.10.10.464
2pwlACPFibroblast growth factor receptor 2/0.464
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.464
3ttjJBIMitogen-activated protein kinase 102.7.11.240.464
4grb0XGCasein kinase II subunit alpha2.7.11.10.464
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.464
4k6z1Q3Tyrosine-protein kinase JAK1/0.464
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.463
3ea4FABAcetolactate synthase, chloroplastic2.2.1.60.463
3rvg17PTyrosine-protein kinase JAK2/0.463
3unk0BYCyclin-dependent kinase 22.7.11.220.463
4fuyEK2Mitogen-activated protein kinase 12.7.11.240.463
4q5hANPProtein kinase OspG2.70.463
4yduADPtRNA N6-adenosine threonylcarbamoyltransferase/0.463
1tqf32PBeta-secretase 13.4.23.460.462
1u54ACPActivated CDC42 kinase 1/0.462
2a4lRRCCyclin-dependent kinase 22.7.11.220.462
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.462
2p33J07Mitogen-activated protein kinase 102.7.11.240.462
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.462
2zawCAMCamphor 5-monooxygenase1.14.15.10.462
3w1f1O5Dual specificity protein kinase TTK2.7.12.10.462
3zw3ZW3Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.462
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.462
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.462
4jr7GNPCasein kinase II subunit alpha2.7.11.10.462
5av4GENDeath-associated protein kinase 12.7.11.10.462
2bmcMPYAurora kinase A2.7.11.10.461
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.461
3hx4ANPCalmodulin-domain protein kinase 1/0.461
3qziX72Cyclin-dependent kinase 22.7.11.220.461
3uimANPBRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 12.7.10.10.461
3vf80JETyrosine-protein kinase SYK2.7.10.20.461
4a99FADTetX family tetracycline inactivation enzyme/0.461
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.461
1drbMTXDihydrofolate reductase1.5.1.30.460
1eh4IC1Casein kinase I homolog 12.7.11.10.460
1ke6LS2Cyclin-dependent kinase 22.7.11.220.460
1oiyN41Cyclin-dependent kinase 22.7.11.220.460
1uu7BI23-phosphoinositide-dependent protein kinase 12.7.11.10.460
1vyw292Cyclin-dependent kinase 22.7.11.220.460
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.460
3c4zADPRhodopsin kinase/0.460
4cd0AWJALK tyrosine kinase receptor2.7.10.10.460
4cegADPAurora kinase A2.7.11.10.460
4eomATPCyclin-dependent kinase 22.7.11.220.460
4i4e1BQFocal adhesion kinase 12.7.10.20.460
4jqeANPCasein kinase II subunit alpha2.7.11.10.460
4l9i8PRRhodopsin kinase/0.460
5aaaVGHALK tyrosine kinase receptor2.7.10.10.460
1h1q2A6Cyclin-dependent kinase 22.7.11.220.459
2btrU73Cyclin-dependent kinase 22.7.11.220.459
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.459
2pvlP55Casein kinase II subunit alpha2.7.11.10.459
2wmxZY6Serine/threonine-protein kinase Chk12.7.11.10.459
3el51UNGag-Pol polyprotein/0.459
3zewSTUEphrin type-B receptor 42.7.10.10.459
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.459
4enyJ19Serine/threonine-protein kinase pim-12.7.11.10.459
1u4dDBQActivated CDC42 kinase 1/0.458
2a4zBYMPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.458
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.458
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.458
3d7tSTUTyrosine-protein kinase CSK/0.458
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.458
3qd03Q43-phosphoinositide-dependent protein kinase 12.7.11.10.458
3vs5VSGTyrosine-protein kinase HCK2.7.10.20.458
3zep1NXTyrosine-protein kinase JAK32.7.10.20.458
4anwO92Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.458
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.458
4dgnLU2Casein kinase II subunit alpha2.7.11.10.458
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.458
5aacVGHALK tyrosine kinase receptor2.7.10.10.458
2btsU32Cyclin-dependent kinase 22.7.11.220.457
2r3gSC9Cyclin-dependent kinase 22.7.11.220.457
2wmvZYVSerine/threonine-protein kinase Chk12.7.11.10.457
3amaSKEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.457
3lxkMI1Tyrosine-protein kinase JAK32.7.10.20.457
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.457
3r1yX76Cyclin-dependent kinase 22.7.11.220.457
3r8lZ30Cyclin-dependent kinase 22.7.11.220.457
3s2pPMUCyclin-dependent kinase 22.7.11.220.457
3tjzGNPADP-ribosylation factor 1/0.457
3vs3VSETyrosine-protein kinase HCK2.7.10.20.457
4c62XWWTyrosine-protein kinase JAK2/0.457
4gii0X6Non-receptor tyrosine-protein kinase TYK22.7.10.20.457
4i22IREEpidermal growth factor receptor2.7.10.10.457
4oauADP2-5A-dependent ribonuclease3.1.260.457
1wvxBD4Death-associated protein kinase 12.7.11.10.456
2c6iDT1Cyclin-dependent kinase 22.7.11.220.456
2pvnP63Casein kinase II subunit alpha2.7.11.10.456
2qhn582Serine/threonine-protein kinase Chk12.7.11.10.456
2xa4AZ5Tyrosine-protein kinase JAK2/0.456
2zv2609Calcium/calmodulin-dependent protein kinase kinase 22.7.11.170.456
3ggu017Gag-Pol polyprotein3.4.23.160.456
3nuuJOZ3-phosphoinositide-dependent protein kinase 12.7.11.10.456
4eon1ROCyclin-dependent kinase 22.7.11.220.456
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.456
4i0s1B5Tyrosine-protein kinase SYK2.7.10.20.456
4iirANPSerine/threonine-protein kinase PRP4 homolog2.7.11.10.456
4y95746Tyrosine-protein kinase/0.456
5l8kADPAurora kinase A2.7.11.10.456
2b7aIZATyrosine-protein kinase JAK2/0.455
2hog710Serine/threonine-protein kinase Chk12.7.11.10.455
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.455
2wotZZGTGF-beta receptor type-12.7.11.300.455
3gxlQIGTGF-beta receptor type-12.7.11.300.455
3qqkX02Cyclin-dependent kinase 22.7.11.220.455
3r71X86Cyclin-dependent kinase 22.7.11.220.455
3vquO22Dual specificity protein kinase TTK2.7.12.10.455
3zonIK1Non-receptor tyrosine-protein kinase TYK22.7.10.20.455
4btjATPTau-tubulin kinase 12.7.11.10.455
4dn5AGSMitogen-activated protein kinase kinase kinase 142.7.11.250.455
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.455
4ft3H1KSerine/threonine-protein kinase Chk12.7.11.10.455
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.455
5cu6ATPCasein kinase II subunit alpha2.7.11.10.455
2izsBRQCasein kinase I isoform gamma-32.7.11.10.454
2j0lANPFocal adhesion kinase 12.7.10.20.454
2qo9ANPEphrin type-A receptor 32.7.10.10.454
2vxoXMPGMP synthase [glutamine-hydrolyzing]6.3.5.20.454
3gubGUBDeath-associated protein kinase 12.7.11.10.454
4f7l0SOCyclin-dependent kinase 82.7.11.220.454
4hge15VTyrosine-protein kinase JAK2/0.454
4hgt15GCasein kinase I isoform delta2.7.11.10.454
4ienCOAPutative acyl-CoA hydrolase/0.454
4riyADPEpidermal growth factor receptor2.7.10.10.454
5fwnNAPPutative dehydrogenase/0.454
1iidNHMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.453
1w0xOLOCyclin-dependent kinase 22.7.11.220.453
2p5cSAHDiphthine synthase/0.453
2pym1UNGag-Pol polyprotein3.4.23.160.453
2vgoAD5Aurora kinase B-A2.7.11.10.453
2w06FRVCyclin-dependent kinase 22.7.11.220.453
2x81ZZLAurora kinase A2.7.11.10.453
3a7hATPSerine/threonine-protein kinase 242.7.11.10.453
3owl19ECasein kinase II subunit alpha2.7.11.10.453
3rukAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.453
3vf9477Tyrosine-protein kinase SYK2.7.10.20.453
3we45FIRibosomal protein S6 kinase beta-12.7.11.10.453
4bgh3I6Cyclin-dependent kinase 22.7.11.220.453
4g170VNCasein kinase I isoform gamma-32.7.11.10.453
4gfg0XFTyrosine-protein kinase SYK2.7.10.20.453
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.453
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.453
1aj8COACitrate synthase/0.452
1g35AHFGag-Pol polyprotein3.4.23.160.452
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
2csnCKICasein kinase I homolog 12.7.11.10.452
2etm7PYFocal adhesion kinase 12.7.10.20.452
2gr1FADFerredoxin reductase/0.452
2wihP48Cyclin-dependent kinase 22.7.11.220.452
2x2mX2MProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.452
2xp2VGHALK tyrosine kinase receptor2.7.10.10.452
2xvdAS6Ephrin type-B receptor 42.7.10.10.452
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.452
3cgfJNFMitogen-activated protein kinase 102.7.11.240.452
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.452
3h9f92MDual specificity protein kinase TTK2.7.12.10.452
3uli1N3Cyclin-dependent kinase 22.7.11.220.452
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.452
4aqc88ATyrosine-protein kinase JAK2/0.452
4btjADPTau-tubulin kinase 12.7.11.10.452
4fg9ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.452
4g6nEK0Mitogen-activated protein kinase 12.7.11.240.452
4hbgNDP3-oxoacyl-[acyl-carrier-protein] reductase1.1.1.1000.452
4j97ACPFibroblast growth factor receptor 2/0.452
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.452
5cp4CAMCamphor 5-monooxygenase1.14.15.10.452
1q97ATPSerine/threonine-protein kinase SKY12.7.11.10.451
2bfyH1NAurora kinase B-A2.7.11.10.451
2j0j4STFocal adhesion kinase 12.7.10.20.451
2qblCAMCamphor 5-monooxygenase1.14.15.10.451
2uzeC95Cyclin-dependent kinase 22.7.11.220.451
2wtiWTISerine/threonine-protein kinase Chk22.7.11.10.451
3e5aVX6Aurora kinase A2.7.11.10.451
3eyhIZATyrosine-protein kinase JAK1/0.451
3qtsX46Cyclin-dependent kinase 22.7.11.220.451
3w18N13Aurora kinase A2.7.11.10.451
4fkj11KCyclin-dependent kinase 22.7.11.220.451
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.451
4ftjH8KSerine/threonine-protein kinase Chk12.7.11.10.451
4hvi19STyrosine-protein kinase JAK32.7.10.20.451
4ix5ANPUncharacterized protein/0.451
4j95ACPFibroblast growth factor receptor 2/0.451
4qpmADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.451
4tuvCPZCytochrome P450 1191.140.451
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.451
1merDMQGag-Pol polyprotein3.4.23.160.450
1pmn984Mitogen-activated protein kinase 102.7.11.240.450
2w05FRTCyclin-dependent kinase 22.7.11.220.450
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.450
2zdt46CMitogen-activated protein kinase 102.7.11.240.450
3iggEFQCyclin-dependent kinase 22.7.11.220.450
3kgaLX9MAP kinase-activated protein kinase 22.7.11.10.450
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.450
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
3rm618ZCyclin-dependent kinase 22.7.11.220.450
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.450
4j16NADNAD/NADP transhydrogenase alpha subunit 1/0.450
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.450
4rqvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.450
1pxoCK7Cyclin-dependent kinase 22.7.11.220.449
2b9fADPMitogen-activated protein kinase FUS32.7.11.240.449
2c6eHPMAurora kinase A2.7.11.10.449
2pziAXXSerine/threonine-protein kinase PknG2.7.11.10.449
2vu3LZECyclin-dependent kinase 22.7.11.220.449
2wmwZYWSerine/threonine-protein kinase Chk12.7.11.10.449
3iahNAPPutative oxoacyl-(Acyl carrier protein) reductase/0.449
3kfs3TLGag-Pol polyprotein/0.449
3lxpIZANon-receptor tyrosine-protein kinase TYK22.7.10.20.449
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.449
3zh8C58Protein kinase C iota type2.7.11.130.449
4bznUGXSerine/threonine-protein kinase pim-12.7.11.10.449
4d58BI9Focal adhesion kinase 12.7.10.20.449
4fkpLS5Cyclin-dependent kinase 22.7.11.220.449
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.449
4fv1EK4Mitogen-activated protein kinase 12.7.11.240.449
4ktc1X3Genome polyprotein3.4.21.980.449
4oavACP2-5A-dependent ribonuclease3.1.260.449
5cvhADPCasein kinase II subunit alpha2.7.11.10.449
1ci7UMPThymidylate synthase2.1.1.450.448
1e8xATPPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
1meuDMPGag-Pol polyprotein3.4.23.160.448
2a0cCK9Cyclin-dependent kinase 22.7.11.220.448
2ckeIQUDeath-associated protein kinase 2/0.448
2r3iSCFCyclin-dependent kinase 22.7.11.220.448
2vwu7X1Ephrin type-B receptor 42.7.10.10.448
3dogNNNCyclin-dependent kinase 22.7.11.220.448
3hmm855TGF-beta receptor type-12.7.11.300.448
3i60E86Mitogen-activated protein kinase 12.7.11.240.448
3u9eCOALmo1369 protein/0.448
3v8t477Tyrosine-protein kinase ITK/TSK2.7.10.20.448
4bcpT3CCyclin-dependent kinase 22.7.11.220.448
4eoi1ROCyclin-dependent kinase 22.7.11.220.448
4fkr45KCyclin-dependent kinase 22.7.11.220.448
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.448
4fx360KCyclin-dependent kinase 22.7.11.220.448
4gncASORegucalcin3.1.1.170.448
4h4xFADBiphenyl dioxygenase ferredoxin reductase subunit/0.448
4jrnANPRhoptry kinase family protein/0.448
4l4cCAMCamphor 5-monooxygenase1.14.15.10.448
4qmpDKISerine/threonine-protein kinase 242.7.11.10.448
5e8xSTUTGF-beta receptor type-12.7.11.300.448
1suoCPZCytochrome P450 2B41.14.14.10.447
1uaeUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.447
1ykdCMPAdenylate cyclase/0.447
2aqkNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.447
2b7zMK1Gag-Pol polyprotein/0.447
2r3r6SCCyclin-dependent kinase 22.7.11.220.447
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.447
3fwiCAMCamphor 5-monooxygenase1.14.15.10.447
3ibqATPPyridoxal kinase/0.447
3mtfA3FActivin receptor type-12.7.11.300.447
3o8tBMUMitogen-activated protein kinase 14/0.447
3oom507Activin receptor type-12.7.11.300.447
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.447
3qtuX44Cyclin-dependent kinase 22.7.11.220.447
3th8TH9Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.447
4acm7YGCyclin-dependent kinase 22.7.11.220.447
4aotGW8Serine/threonine-protein kinase 102.7.11.10.447
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.447
4brxKGWFocal adhesion kinase 12.7.10.20.447
4c4g7RODual specificity protein kinase TTK2.7.12.10.447
4d4sBI9Focal adhesion kinase 12.7.10.20.447
4e6d0NUTyrosine-protein kinase JAK2/0.447
4fg8ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.447
4hvh19RTyrosine-protein kinase JAK32.7.10.20.447
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.447
4r20AERCytochrome P450 family 17 polypeptide 2/0.447
1fvv107Cyclin-dependent kinase 22.7.11.220.446
1pxpCK8Cyclin-dependent kinase 22.7.11.220.446
1t87CAMCamphor 5-monooxygenase1.14.15.10.446
1yvj4STTyrosine-protein kinase JAK32.7.10.20.446
1zarADPRIO-type serine/threonine-protein kinase Rio22.7.11.10.446
2c5nCK8Cyclin-dependent kinase 22.7.11.220.446
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.446
3mdmFJZCholesterol 24-hydroxylase/0.446
3okxSAMS-adenosyl-L-methionine-binding protein RPA0152/0.446
3ortAGSSerine/threonine protein kinase/0.446
3qruX19Cyclin-dependent kinase 22.7.11.220.446
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.446
4anqVGHALK tyrosine kinase receptor2.7.10.10.446
4fob0USALK tyrosine kinase receptor2.7.10.10.446
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.446
4o1pANPRibonuclease L/0.446
5e92ANPTGF-beta receptor type-22.7.11.300.446
1bwsNDPGDP-L-fucose synthase/0.445
1zrzBI1Protein kinase C iota type2.7.11.130.445
2c4g514Cyclin-dependent kinase 22.7.11.220.445
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.445
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
2cn8DBQSerine/threonine-protein kinase Chk22.7.11.10.445
2gjnFMNNitronate monooxygenase1.13.12.160.445
2jkoBIJFocal adhesion kinase 12.7.10.20.445
2r3wG3GGag-Pol polyprotein3.4.23.160.445
2r5q1UNGag-Pol polyprotein/0.445
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
3lxiCAMCytochrome P450/0.445
3nd1SAHPrecorrin-6A synthase (Deacetylating)/0.445
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.445
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
4ivc1J6Tyrosine-protein kinase JAK1/0.445
1g2vTTPGlucose-1-phosphate thymidylyltransferase/0.444
1pmv537Mitogen-activated protein kinase 102.7.11.240.444
1pxlCK4Cyclin-dependent kinase 22.7.11.220.444
1uu3LY43-phosphoinositide-dependent protein kinase 12.7.11.10.444
2bkzSBCCyclin-dependent kinase 22.7.11.220.444
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.444
2c6tDT5Cyclin-dependent kinase 22.7.11.220.444
2i51FMNPyridoxamine 5'-phosphate oxidase-related, FMN-binding/0.444
2izrBRKCasein kinase I isoform gamma-32.7.11.10.444
2z97CAMCamphor 5-monooxygenase1.14.15.10.444
3el4ROCGag-Pol polyprotein3.4.23.160.444
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.444
3nga3NGCasein kinase II subunit alpha2.7.11.10.444
3nynSGVG protein-coupled receptor kinase 62.7.11.160.444
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.444
3zuxTCHTransporter/0.444
4gfo0X2Non-receptor tyrosine-protein kinase TYK22.7.10.20.444
4h8aNAIUreidoglycolate dehydrogenase (NAD(+))1.1.1.3500.444
4hvg19QTyrosine-protein kinase JAK32.7.10.20.444
1g5sI17Cyclin-dependent kinase 22.7.11.220.443
1ke7LS3Cyclin-dependent kinase 22.7.11.220.443
1tvoFRZMitogen-activated protein kinase 12.7.11.240.443
1vrwNAIEnoyl-ACP reductase/0.443
1xddAAYIntegrin alpha-L/0.443
2biyATP3-phosphoinositide-dependent protein kinase 12.7.11.10.443
2bujSTUSerine/threonine-protein kinase 16/0.443
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.443
2nmxM25Carbonic anhydrase 14.2.1.10.443
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.443
3axwTIDCasein kinase II subunit alpha2.7.11.10.443
3ekx1UNGag-Pol polyprotein3.4.23.160.443
3gb2G3BGlycogen synthase kinase-3 beta2.7.11.260.443
3mdvCL6Cholesterol 24-hydroxylase/0.443
3qxoX65Cyclin-dependent kinase 22.7.11.220.443
3rm719ZCyclin-dependent kinase 22.7.11.220.443
3rpv26ZCyclin-dependent kinase 22.7.11.220.443
3zsi52PMitogen-activated protein kinase 14/0.443
3zvvXAZPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4fkg4CKCyclin-dependent kinase 22.7.11.220.443
4fkt48KCyclin-dependent kinase 22.7.11.220.443
4fsmHK1Serine/threonine-protein kinase Chk12.7.11.10.443
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.443
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4idtT28Mitogen-activated protein kinase kinase kinase 142.7.11.250.443
4iwd1JCHepatocyte growth factor receptor2.7.10.10.443
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.443
4mwhATPCasein kinase II subunit alpha2.7.11.10.443
4oacADPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.443
4ocvANPAminoglycoside phosphotransferase/0.443
4wq4ATPtRNA N6-adenosine threonylcarbamoyltransferase/0.443
4xf7ACPCarbohydrate/pyrimidine kinase, PfkB family/0.443
1gebCAMCamphor 5-monooxygenase1.14.15.10.442
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.442
1v9aSAHUncharacterized protein/0.442
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.442
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.442
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.442
2xs0ANPMitogen-activated protein kinase 82.7.11.240.442
3bu5ATPInsulin receptor2.7.10.10.442
3cktYDPGag-Pol polyprotein3.4.23.160.442
3cs8BRLPeroxisome proliferator-activated receptor gamma/0.442
3g6wGTPUracil phosphoribosyltransferase2.4.2.90.442
3nu3478Gag-Pol polyprotein3.4.23.160.442
3p7nFMNLight-activated DNA-binding protein EL222/0.442
3rusADPChaperonin/0.442
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.442
4i8x6P3L-lactate dehydrogenase A chain1.1.1.270.442
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.442
4wq5ATPtRNA N6-adenosine threonylcarbamoyltransferase/0.442
4yswFADXanthine dehydrogenase/oxidase/0.442
4zseANPEpidermal growth factor receptor2.7.10.10.442
5auxKMPDeath-associated protein kinase 12.7.11.10.442
6cp4CAMCamphor 5-monooxygenase1.14.15.10.442
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
1hiiC20Gag-Pol polyprotein/0.441
1pkgADPMast/stem cell growth factor receptor Kit2.7.10.10.441
2a5uQYTPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.441
2cmwOLPCasein kinase I isoform gamma-12.7.11.10.441
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.441
2jc6QPPCalcium/calmodulin-dependent protein kinase type 1D2.7.11.170.441
2vwz7X6Ephrin type-B receptor 42.7.10.10.441
2zaxCAMCamphor 5-monooxygenase1.14.15.10.441
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.441
3em6017Gag-Pol polyprotein3.4.23.160.441
3fwgCAMCamphor 5-monooxygenase1.14.15.10.441
3fwjCAMCamphor 5-monooxygenase1.14.15.10.441
3ogqAB1Pol polyprotein/0.441
3r3sNADPutative oxidoreductase/0.441
3rak03ZCyclin-dependent kinase 22.7.11.220.441
3uzp0CKCasein kinase I isoform delta2.7.11.10.441
3vt7VDXVitamin D3 receptor/0.441
4bcmT7ZCyclin-dependent kinase 22.7.11.220.441
4fkq42KCyclin-dependent kinase 22.7.11.220.441
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.441
1dayGNPCasein kinase II subunit alpha2.7.11.10.440
1h1pCMGCyclin-dependent kinase 22.7.11.220.440
1iwjCAMCamphor 5-monooxygenase1.14.15.10.440
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.440
1m0wANPGlutathione synthetase6.3.2.30.440
1oiuN76Cyclin-dependent kinase 22.7.11.220.440
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.440
1v0pPVBCell division control protein 2 homolog2.7.11.220.440
2i5bADPPyridoxine kinase/0.440
2izuP01Casein kinase I isoform gamma-32.7.11.10.440
2r43G3GGag-Pol polyprotein3.4.23.160.440
2xb7GUIALK tyrosine kinase receptor2.7.10.10.440
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.440
2ycfYCFSerine/threonine-protein kinase Chk22.7.11.10.440
3dpd41APhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
3eb0DRKUncharacterized protein/0.440
3lj3WYEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
3orpAGSSerine/threonine protein kinase/0.440
3r3b4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.440
3ttiKBIMitogen-activated protein kinase 102.7.11.240.440
3umw596Serine/threonine-protein kinase pim-12.7.11.10.440
3vs4VSFTyrosine-protein kinase HCK2.7.10.20.440
3zptM8YGag-Pol polyprotein3.4.23.160.440
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.440
4f081RSTyrosine-protein kinase JAK2/0.440
4i8vBHFCytochrome P450 1A11.14.14.10.440
4l521ULMitogen-activated protein kinase kinase kinase 72.7.11.250.440
4lfiGNPCasein kinase II subunit alpha2.7.11.10.440
4nks2M2Fibroblast growth factor receptor 1/0.440