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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2qe5617Polyprotein

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2qe5617Polyprotein/1.000
3golXNDGenome polyprotein2.7.7.480.613
3e51N35Genome polyprotein2.7.7.480.603
3hkyIX6Genome polyprotein2.7.7.480.601
4ih71ERGenome polyprotein2.7.7.480.586
1z4uPH9Polyprotein/0.583
3h5sH5SGenome polyprotein2.7.7.480.582
4iz02BIGenome polyprotein2.7.7.480.581
3co93MSGenome polyprotein2.7.7.480.580
2fvc888Polyprotein/0.574
3cvkN34Genome polyprotein2.7.7.480.573
3ske054Genome polyprotein2.7.7.480.571
1yvfPH7Polyprotein/0.569
3gnvXNZGenome polyprotein2.7.7.480.563
3upi0C2Genome polyprotein2.7.7.480.561
4mk728OGenome polyprotein2.7.7.480.561
3tyvHI3Genome polyprotein2.7.7.480.559
3cwj321Genome polyprotein2.7.7.480.557
3u4r08FGenome polyprotein2.7.7.480.556
3h98B5PGenome polyprotein2.7.7.480.555
3h5uH5UGenome polyprotein2.7.7.480.554
3d5m4MSGenome polyprotein2.7.7.480.553
3ska053Genome polyprotein2.7.7.480.550
3igvB80Genome polyprotein2.7.7.480.540
3gynB42Genome polyprotein2.7.7.480.539
3bsa1PDGenome polyprotein2.7.7.480.538
3h59H59Genome polyprotein2.7.7.480.532
4eqsCOACoenzyme A disulfide reductase/0.527
3gnwXNCGenome polyprotein2.7.7.480.523
4eaw0NQGenome polyprotein2.7.7.480.517
1yqzCOACoenzyme A disulfide reductase/0.513
3fqk79ZGenome polyprotein2.7.7.480.502
1z3cSA8mRNA cap guanine-N7 methyltransferase2.1.1.560.499
5hwrCOAHydroxymethylglutaryl-CoA synthase/0.495
1d3dBZTProthrombin3.4.21.50.494
1d3pBT3Prothrombin3.4.21.50.494
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.488
1w6hTITPlasmepsin-23.4.23.390.487
4e2bFMNDehydrogenase/0.486
2zhw12UProthrombin3.4.21.50.485
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.485
2anmCDOProthrombin3.4.21.50.484
3b9lAZZSerum albumin/0.484
3fp0FP015-O-acetyltransferase/0.484
3nmpPYVAbscisic acid receptor PYL2/0.484
2pk3A2RGDP-6-deoxy-D-mannose reductase/0.482
3nn6HNK6-hydroxy-L-nicotine oxidase/0.482
4f3gKAIGlutamate receptor 3/0.481
1ni4TPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.480
1ni4TPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.480
4twnB96Ephrin type-A receptor 32.7.10.10.480
1c3x8IGPurine nucleoside phosphorylase2.4.2.10.479
5a3cNADSIR2 family protein/0.479
1p0pBCHCholinesterase3.1.1.80.478
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.478
1gzuNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.477
1t4v14AProthrombin3.4.21.50.477
3c35KAIGlutamate receptor ionotropic, kainate 1/0.477
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.477
3f03FMNPentaerythritol tetranitrate reductase/0.476
3maaFKPAdenylate cyclase type 2/0.476
3maaFKPAdenylate cyclase type 5/0.476
3ndcSAHPrecorrin-4 C(11)-methyltransferase2.1.1.1330.476
4eqrCOACoenzyme A disulfide reductase/0.476
1tkcM6TTransketolase 12.2.1.10.475
1t4u81AProthrombin3.4.21.50.474
3mddFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.474
4c72TLG3-oxoacyl-ACP synthase/0.474
4cdmFO1Deoxyribodipyrimidine photolyase/0.474
4y35F90Endothiapepsin3.4.23.220.474
1zgi382Prothrombin3.4.21.50.473
2bdyUNBProthrombin3.4.21.50.473
3exhTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.473
3exhTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.473
4r1lADPPhenylacetate-coenzyme A ligase/0.473
1bsvNDPGDP-L-fucose synthase/0.472
2a0wDIHPurine nucleoside phosphorylase2.4.2.10.472
2fjdSFDAdenylylsulfate reductase, subunit A (AprA)/0.472
2pksG44Prothrombin3.4.21.50.472
2r2mI50Prothrombin3.4.21.50.472
3t4nADP5'-AMP-activated protein kinase subunit gamma/0.472
5akk1P8Bifunctional epoxide hydrolase 23.1.3.760.472
2geuCOKPantothenate kinase2.7.1.330.471
3otwCOAPhosphopantetheine adenylyltransferase/0.471
4eqwCOACoenzyme A disulfide reductase/0.471
1xm1GAHProthrombin3.4.21.50.470
4gllNADUDP-glucuronic acid decarboxylase 14.1.1.350.470
4jxrACOAcetyltransferase/0.470
1ay0TPPTransketolase 12.2.1.10.469
1g1aNADdTDP-glucose 4,6-dehydratase/0.469
3ekuCY9Actin-5C/0.469
4e2dFMNDehydrogenase/0.469
3af0GDPPantothenate kinase2.7.1.330.468
3c15FOKAdenylate cyclase type 2/0.468
3c15FOKAdenylate cyclase type 5/0.468
3djfBC3Purine nucleoside phosphorylase/0.468
3mauPLRPutative sphingosine-1-phosphate lyase/0.468
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.468
4s1iPLPPyridoxal kinase, putative/0.468
1ypjUIBProthrombin3.4.21.50.467
3sl2ATPSensor histidine kinase WalK/0.467
4bahMELProthrombin3.4.21.50.467
4ce3L4VATP-dependent molecular chaperone HSP82/0.467
5a88ADPRiboflavin biosynthesis protein RibF2.7.1.260.467
1o9bNAIQuinate/shikimate dehydrogenase/0.466
2wkyIBCGlutamate receptor ionotropic, kainate 1/0.466
4rvnCOAPhenylacetate-coenzyme A ligase/0.466
1cjtFOKAdenylate cyclase type 2/0.465
1cjtFOKAdenylate cyclase type 5/0.465
1d4pBPPProthrombin3.4.21.50.465
3c1kT15Prothrombin3.4.21.50.465
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.465
1lf2R37Plasmepsin-23.4.23.390.464
1nvtNAPShikimate dehydrogenase (NADP(+))/0.464
1tysTMPThymidylate synthase/0.464
1uyhPU0Heat shock protein HSP 90-alpha/0.464
1y2d4DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.464
2imlFMNUncharacterized protein/0.464
2zrzFNRIsopentenyl-diphosphate delta-isomerase/0.464
5hwoHMGHydroxymethylglutaryl-CoA synthase/0.464
1gj5130Prothrombin3.4.21.50.463
1piwNAPNADP-dependent alcohol dehydrogenase 61.1.1.20.463
2e0nSAHPrecorrin-2 C20-methyltransferase/0.463
2gjlFMNNitronate monooxygenase1.13.12.160.463
2v1aFMNNPH1-1/0.463
3dzkNMNADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.463
3i8p8403-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.463
3in6FMNUncharacterized protein/0.463
3sqzCOAPutative hydroxymethylglutaryl-CoA synthase/0.463
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.463
4xnw2IDP2Y purinoceptor 1/0.463
1h5qNAPNADP-dependent mannitol dehydrogenase1.1.1.1380.462
1nzfUPGDNA beta-glucosyltransferase/0.462
1qy8RDIEndoplasmin/0.462
1uycPU7Heat shock protein HSP 90-alpha/0.462
2a1hGBNBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.462
2c29NAPDihydroflavonol 4-reductase/0.462
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.462
2r8pT6FTransketolase 1/0.462
2vmyFFOSerine hydroxymethyltransferase/0.462
3s1dZIRCytokinin dehydrogenase 11.5.99.120.462
3zkyWT4Isopenicillin N synthase1.21.3.10.462
4nh82LCHeat shock protein HSP 90-alpha/0.462
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.462
5a3bAPRSIR2 family protein/0.462
1dmyAZMCarbonic anhydrase 5A, mitochondrial4.2.1.10.461
1f8gNADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.461
1h50FMNPentaerythritol tetranitrate reductase/0.461
1nm6L86Prothrombin3.4.21.50.461
1xddAAYIntegrin alpha-L/0.461
1yplRA8Prothrombin3.4.21.50.461
2ddoATPPyridoxine/pyridoxal/pyridoxamine kinase/0.461
2uuk897Prothrombin3.4.21.50.461
2vcmM11Isopenicillin N synthase1.21.3.10.461
3b05IPEIsopentenyl-diphosphate delta-isomerase/0.461
3fr5I4AFatty acid-binding protein, adipocyte/0.461
3iexGMPPurine nucleoside phosphorylase/0.461
3v2uATPProtein GAL3/0.461
4dieC5PCytidylate kinase/0.461
4h3j10WBeta-secretase 13.4.23.460.461
4l5aTBNS-methyl-5'-thioadenosine phosphorylase/0.461
1bk0ACVIsopenicillin N synthase1.21.3.10.460
1kc1NDPdTDP-4-dehydrorhamnose reductase1.1.1.1330.460
1lbbKAIGlutamate receptor 2/0.460
1y2c3DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.460
2ft9CHDFatty acid-binding protein 2, liver/0.460
2g1n1IGRenin3.4.23.150.460
2g8yNADHydroxycarboxylate dehydrogenase B/0.460
3b05FNRIsopentenyl-diphosphate delta-isomerase/0.460
3djjFADGlutathione reductase, mitochondrial1.8.1.70.460
3ssoSAHMycinamicin VI 2''-O-methyltransferase/0.460
3to3ATPPetrobactin biosynthesis protein AsbB/0.460
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.459
2ykeYKEHeat shock protein HSP 90-alpha/0.459
3eksCY9Actin-5C/0.459
4br0AU1Ectonucleoside triphosphate diphosphohydrolase 2/0.459
4hy6FJ1Heat shock protein HSP 90-alpha/0.459
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.459
1bxkNADdTDP-glucose 4,6-dehydratase 2/0.458
1fw0KAIGlutamate receptor 2/0.458
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.458
2a94AP0L-lactate dehydrogenase1.1.1.270.458
2ejzSAHDiphthine synthase/0.458
2fypRDEEndoplasmin/0.458
3clsFADElectron transfer flavoprotein subunit alpha/0.458
3dhbC6LN-acyl homoserine lactonase AiiA3.1.1.810.458
3ihgVAKAklavinone 12-hydroxylase RdmE/0.458
3qt62P0Mevalonate diphosphate decarboxylase/0.458
4b79NADProbable short-chain dehydrogenase/0.458
4oztP1AEcdysone receptor, putative/0.458
4rww2BALmo2692 protein/0.458
4udrFAD5-(hydroxymethyl)furfural oxidase/0.458
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.458
1b2lNDCAlcohol dehydrogenase1.1.1.10.457
1blzACVIsopenicillin N synthase1.21.3.10.457
1ikgREXD-alanyl-D-alanine carboxypeptidase3.4.16.40.457
1obnASVIsopenicillin N synthase1.21.3.10.457
2xw7NDPDihydrofolate reductase/0.457
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.457
3zhrTPPMultifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.457
4djw0KPBeta-secretase 13.4.23.460.457
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.456
1h74ADPHomoserine kinase2.7.1.390.456
1icuFMNOxygen-insensitive NAD(P)H nitroreductase/0.456
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.456
2c20NADUDP-glucose 4-epimerase/0.456
2xlrFADPutative flavin-containing monooxygenase/0.456
2zfr46UProthrombin3.4.21.50.456
2zs8ADPPantothenate kinase2.7.1.330.456
3r5yF42Uncharacterized protein/0.456
3wmxNADNAD dependent epimerase/dehydratase/0.456
4j03FVSBifunctional epoxide hydrolase 23.1.3.760.456
1cs4FOKAdenylate cyclase type 2/0.455
1cs4FOKAdenylate cyclase type 5/0.455
1ri3SAHmRNA cap guanine-N7 methyltransferase2.1.1.560.455
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.455
2ea1GPGRibonuclease I3.1.27.60.455
2hxzH7JCathepsin S3.4.22.270.455
2i65NADADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.455
2jbsFMNp-hydroxyphenylacetate 3-hydroxylase, oxygenase component/0.455
2vkeTACTetracycline repressor protein class D/0.455
2zhf49UProthrombin3.4.21.50.455
3bv2P38Mitogen-activated protein kinase 14/0.455
3k974CDHeat shock protein HSP 90-alpha/0.455
3rlq3RQHeat shock protein HSP 90-alpha/0.455
3zw9NADPeroxisomal bifunctional enzyme1.1.1.350.455
4c717RD3-oxoacyl-ACP synthase/0.455
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.455
4nd3NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.455
4r1fADPDNA topoisomerase 2-alpha5.99.1.30.455
1z1fSTLResveratrol synthase/0.454
2ol0DUDDUTP pyrophosphatase/0.454
2p9cNAID-3-phosphoglycerate dehydrogenase1.1.1.950.454
2rlcCHDCholoylglycine hydrolase3.5.1.240.454
2vb8TLM3-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.454
2wi72KLHeat shock protein HSP 90-alpha/0.454
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.454
2y6fM9FIsopenicillin N synthase1.21.3.10.454
3ac1KZITyrosine-protein kinase Lck2.7.10.20.454
3fhxPXLPyridoxal kinase2.7.1.350.454
3fun798Leukotriene A-4 hydrolase3.3.2.60.454
3h06VBPGlutamate receptor 2/0.454
1fxsNAPGDP-L-fucose synthase/0.453
1r2jFADFkbI/0.453
1zgv501Prothrombin3.4.21.50.453
2rqfJH3Hemolymph juvenile hormone binding protein/0.453
2vprTDCTetracycline repressor protein class H/0.453
3c36KAIGlutamate receptor ionotropic, kainate 1/0.453
3wtkTH4Acetylcholine-binding protein/0.453
4dc0NDPPutative ketoacyl reductase1.3.10.453
4kwhNAPReductase homolog/0.453
4l5b1UXDeoxycytidine kinase2.7.1.740.453
1e1qADPATP synthase subunit beta, mitochondrial3.6.3.140.452
1hb1OCVIsopenicillin N synthase1.21.3.10.452
1sb1165Prothrombin3.4.21.50.452
1sd1FMCS-methyl-5'-thioadenosine phosphorylase/0.452
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.452
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.452
2fj1CTCTetracycline repressor protein class D/0.452
2vbpVB1Isopenicillin N synthase1.21.3.10.452
3dhcCYKN-acyl homoserine lactonase AiiA3.1.1.810.452
3fhxPLPPyridoxal kinase2.7.1.350.452
3ou2SAHSAM-dependent methyltransferase/0.452
4bqjXKLHeat shock protein HSP 90-alpha/0.452
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.452
4cvmANPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.452
4kxjP34Nucleoprotein/0.452
5dp2NAPCurF/0.452
1c4uIH1Prothrombin3.4.21.50.451
1f20FADNitric oxide synthase, brain1.14.13.390.451
1o2g696Prothrombin3.4.21.50.451
1vfrFMNMajor NAD(P)H-flavin oxidoreductase1.6.990.451
1y2k7DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.451
1y4lSVRBasic phospholipase A2 homolog 2/0.451
2ftoTMPThymidylate synthase/0.451
2gevCOKPantothenate kinase2.7.1.330.451
2ofv242Tyrosine-protein kinase Lck2.7.10.20.451
3fazNOSPurine nucleoside phosphorylase/0.451
3ful52DLeukotriene A-4 hydrolase3.3.2.60.451
4b4w9L9Bifunctional protein FolD/0.451
4c6zTLE3-oxoacyl-ACP synthase/0.451
4uyg73BBromodomain-containing protein 2/0.451
4y1bNAPAntE/0.451
4yerADPAntibiotic ABC transporter, ATP-binding protein, putative/0.451
5stdUNNScytalone dehydratase4.2.1.940.451
1ae8AZLProthrombin3.4.21.50.450
1kquBR4Phospholipase A2, membrane associated/0.450
1ri1GTGmRNA cap guanine-N7 methyltransferase2.1.1.560.450
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.450
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.450
2zrxFMNIsopentenyl-diphosphate delta-isomerase/0.450
3b9xNOSPyrimidine-specific ribonucleoside hydrolase RihB3.2.2.80.450
3g4gD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.450
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
4kp71UQ1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic1.1.1.2670.450
4kw51W6Decaprenylphosphoryl-beta-D-ribose oxidase/0.450
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.450
5efwFMNNPH1-1/0.450
3qakUKAAdenosine receptor A2a/0.450
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.449
1x1cSAHC-20 methyltransferase/0.449
2a57CRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.449
2ab8MTPAdenosine kinase2.7.1.200.449
2aq7TL53-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.449
2gv8FADThiol-specific monooxygenase1.14.130.449
2jlaTPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.449
2xviFADPutative flavin-containing monooxygenase/0.449
2zda32UProthrombin3.4.21.50.449
3b8z294A disintegrin and metalloproteinase with thrombospondin motifs 53.4.240.449
3bi6396Wee1-like protein kinase2.7.10.20.449
3d3wNAPL-xylulose reductase1.1.1.100.449
3oetNADErythronate-4-phosphate dehydrogenase/0.449
3qto10PProthrombin3.4.21.50.449
4ho8THMGlucose-1-phosphate thymidylyltransferase/0.449
5hwqCAAHydroxymethylglutaryl-CoA synthase/0.449
1a5bIGPTryptophan synthase alpha chain/0.448
1i7pFADNADH-cytochrome b5 reductase 31.6.2.20.448
1m9nAMZBifunctional purine biosynthesis protein PURH2.1.2.30.448
1pjcNADAlanine dehydrogenase/0.448
1pq944BOxysterols receptor LXR-beta/0.448
1trbFADThioredoxin reductase1.8.1.90.448
1udaUFGUDP-glucose 4-epimerase5.1.3.20.448
2jh5895Prothrombin3.4.21.50.448
2kceD16Thymidylate synthase/0.448
2qtaTDPPyruvate dehydrogenase E1 component1.2.4.10.448
2yvwEPUUDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.448
2zfq45UProthrombin3.4.21.50.448
3cgbCOACoenzyme A disulfide reductase/0.448
3v0p4GWHisto-blood group ABO system transferase/0.448
3v0tATRPerakine reductase1.1.1.3170.448
3w8eNAD3-hydroxybutyrate dehydrogenase/0.448
3zxzKRWHepatocyte growth factor receptor2.7.10.10.448
4ckbSAHmRNA-capping enzyme catalytic subunit2.1.1.560.448
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.448
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.448
4h1e10JBeta-secretase 13.4.23.460.448
4n3l2FNProthrombin3.4.21.50.448
5c77SAHProtein arginine N-methyltransferase SFM1/0.448
1b5eDCMDeoxycytidylate 5-hydroxymethyltransferase2.1.2.80.447
1d6w00RProthrombin3.4.21.50.447
1ek5NADUDP-glucose 4-epimerase/0.447
1fmlRTLRetinol dehydratase/0.447
1kr2TADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.447
1kvkATPMevalonate kinase2.7.1.360.447
2ykiYKIHeat shock protein HSP 90-alpha/0.447
2zgx29UProthrombin3.4.21.50.447
2zhq27UProthrombin3.4.21.50.447
3a0tADPSensor histidine kinase/0.447
3b03VNRIsopentenyl-diphosphate delta-isomerase/0.447
3id8MRKGlucokinase2.7.1.20.447
3nj0PYVAbscisic acid receptor PYL2/0.447
3qdlFMNOxygen-insensitive NADPH nitroreductase/0.447
3t4hMD5Alpha-ketoglutarate-dependent dioxygenase AlkB1.14.11.330.447
4c6uTLG3-oxoacyl-ACP synthase/0.447
4eepFMNPhototropin-22.7.11.10.447
4fweFADLysine-specific histone demethylase 1B10.447
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.447
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.447
4m5pFMNNADPH dehydrogenase/0.447
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.447
4tqgNDPPutative dTDP-d-glucose 4 6-dehydratase/0.447
1culFOKAdenylate cyclase type 2/0.446
1culFOKAdenylate cyclase type 5/0.446
1dhrNADDihydropteridine reductase1.5.1.340.446
1hfqMOTDihydrofolate reductase1.5.1.30.446
1nzq162Prothrombin3.4.21.50.446
1srgMHBStreptavidin/0.446
1thnADPAnti-sigma F factor/0.446
1v3q2DIPurine nucleoside phosphorylase2.4.2.10.446
2h55DZ8Heat shock protein HSP 90-alpha/0.446
2p8uCOAHydroxymethylglutaryl-CoA synthase, cytoplasmic2.3.3.100.446
2yee2ECHeat shock protein HSP 90-alpha/0.446
2zc922UProthrombin3.4.21.50.446
3p8iFMNPentaerythritol tetranitrate reductase/0.446
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.446
3t7qRB4Endothiapepsin3.4.23.220.446
3tjsD0RCytochrome P450 3A4/0.446
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.446
4bbhYBNGlycylpeptide N-tetradecanoyltransferase/0.446
4gk2L66Ephrin type-A receptor 32.7.10.10.446
4k28NADShikimate dehydrogenase family protein/0.446
4l4eCAMCamphor 5-monooxygenase1.14.15.10.446
4ocvANPAminoglycoside phosphotransferase/0.446
4uwmFMN3,6-diketocamphane 1,6 monooxygenase1.14.130.446
1a8rGTPGTP cyclohydrolase 13.5.4.160.445
1g9cBABBotulinum neurotoxin type B3.4.24.690.445
1lbcCYZGlutamate receptor 2/0.445
1mrqSTRAldo-keto reductase family 1 member C1/0.445
1td2PXLPyridoxal kinase PdxY/0.445
1udbUFGUDP-glucose 4-epimerase5.1.3.20.445
1z6tADPApoptotic protease-activating factor 1/0.445
2ggsNDPdTDP-4-dehydrorhamnose reductase/0.445
2op18PCEnoyl-ACP reductase/0.445
2v3hI25Prothrombin3.4.21.50.445
2zreAGSProtein RecA/0.445
3c3dFO12-phospho-L-lactate transferase/0.445
3qwc98PProthrombin3.4.21.50.445
3zrlZRLGlycogen synthase kinase-3 beta2.7.11.260.445
4friDWABeta-secretase 13.4.23.460.445
4nmdFDABifunctional protein PutA/0.445
1mg5NAIAlcohol dehydrogenase1.1.1.10.444
1nzdUPGDNA beta-glucosyltransferase/0.444
1tehNADAlcohol dehydrogenase class-31.1.1.10.444
1u2yGOXPancreatic alpha-amylase/0.444
2b4qNAPRhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase1.1.1.1000.444
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.444
3hl0NADMaleylacetate reductase/0.444
3mjeNDPAmphB/0.444
3o6o94MHeat shock protein 83/0.444
3pce3HPProtocatechuate 3,4-dioxygenase alpha chain1.13.11.30.444
3pce3HPProtocatechuate 3,4-dioxygenase beta chain1.13.11.30.444
3tgpGNPGTPase HRas/0.444
4a16H34Acetylcholinesterase3.1.1.70.444
4a6rTA8Probable aminotransferase/0.444
4bfuZVUPantothenate kinase2.7.1.330.444
4dpy2P0Mevalonate diphosphate decarboxylase/0.444
4fcr0TMHeat shock protein HSP 90-alpha/0.444
1knpFADL-aspartate oxidase1.4.3.160.443
1lb9DNQGlutamate receptor 2/0.443
1lkeDOGBilin-binding protein/0.443
2abbFMNPentaerythritol tetranitrate reductase/0.443
2gv8NDPThiol-specific monooxygenase1.14.130.443
2ihuTP9N(2)-(2-carboxyethyl)arginine synthase/0.443
2ldbNADL-lactate dehydrogenase1.1.1.270.443
2nmtMIMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.443
2webPP4Penicillopepsin-13.4.23.200.443
2zshGA3Gibberellin receptor GID1A30.443
3aivHBO4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic3.2.1.1820.443
3atyFMNProstaglandin F2a synthase/0.443
3atzFMNProstaglandin F2a synthase/0.443
3gn73GNPoly [ADP-ribose] polymerase 12.4.2.300.443
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.443
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.443
4bakM67Prothrombin3.4.21.50.443
4du82P0Mevalonate diphosphate decarboxylase/0.443
4n5nNAPAcetoacetyl-CoA reductase1.1.1.360.443
4pkl1GHUncharacterized protein/0.443
5c3zACPRibokinase/0.443
1fwkADPHomoserine kinase2.7.1.390.442
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.442
1j9zFADNADPH--cytochrome P450 reductase/0.442
1kbo340NAD(P)H dehydrogenase [quinone] 11.6.5.20.442
1lolXMPOrotidine 5'-phosphate decarboxylase4.1.1.230.442
1n3sGTPGTP cyclohydrolase 13.5.4.160.442
1rdwLARActin, alpha skeletal muscle/0.442
1tl7FOKAdenylate cyclase type 2/0.442
1tl7FOKAdenylate cyclase type 5/0.442
2bxqIMNSerum albumin/0.442
2ejvNADL-threonine 3-dehydrogenase/0.442
2h94FADLysine-specific histone demethylase 1A10.442
2on6IMHPurine nucleoside phosphorylase2.4.2.10.442
2ywlFADThioredoxin reductase related protein/0.442
2yy7NADL-threonine dehydrogenase/0.442
2ztvNADD(-)-3-hydroxybutyrate dehydrogenase/0.442
3h3r14HCollagen type IV alpha-3-binding protein/0.442
3nglNAPBifunctional protein FolD/0.442
3p62FMNPentaerythritol tetranitrate reductase/0.442
3qgtCP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.442
3tjlFMNNADPH dehydrogenase/0.442
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.442
4kgkGTPUncharacterized protein/0.442
5a8aADPRiboflavin biosynthesis protein RibF2.7.1.260.442
1k27MTMS-methyl-5'-thioadenosine phosphorylase/0.441
1kvsUPGUDP-glucose 4-epimerase5.1.3.20.441
1p0hCOAMycothiol acetyltransferase2.3.1.1890.441
1pd9CO4Dihydrofolate reductase1.5.1.30.441
2idkC2FGlycine N-methyltransferase2.1.1.200.441
2pnjCHDFerrochelatase, mitochondrial4.99.1.10.441
2q7oIMHPurine nucleoside phosphorylase2.4.2.10.441
2yk2YJWHeat shock protein HSP 90-alpha/0.441
3cb2GDPTubulin gamma-1 chain/0.441
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.441
3fwjCAMCamphor 5-monooxygenase1.14.15.10.441
3h3sH15Collagen type IV alpha-3-binding protein/0.441
3hz5Z64Heat shock protein HSP 90-alpha/0.441
3kry3KRCollagenase 33.4.240.441
3lsiFADPyranose 2-oxidase/0.441
3o56ZG1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.441
3p67FMNPentaerythritol tetranitrate reductase/0.441
3rlr3RRHeat shock protein HSP 90-alpha/0.441
3vt7VDXVitamin D3 receptor/0.441
4dpuAGSMevalonate diphosphate decarboxylase/0.441
4f7iNAD3-isopropylmalate dehydrogenase1.1.1.850.441
4fhd0TTSpore photoproduct lyase/0.441
4i6gFADCryptochrome-2/0.441
4l82FMNUncharacterized protein/0.441
4lngJANCaaX farnesyltransferase beta subunit Ram1/0.441
4tlaADPCircadian clock protein kinase KaiC2.7.11.10.441
4ubtCOASteroid 3-ketoacyl-CoA thiolase/0.441
4xbfFADLysine-specific histone demethylase 1A10.441
1a26CNAPoly [ADP-ribose] polymerase 12.4.2.300.440
1ao05GPAmidophosphoribosyltransferase/0.440
1cf3FADGlucose oxidase1.1.3.40.440
1dxoFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.440
1h63FMNPentaerythritol tetranitrate reductase/0.440
1mvtDTMDihydrofolate reductase1.5.1.30.440
1nhhANPDNA mismatch repair protein MutL/0.440
1osvCHCBile acid receptor/0.440
1q19SSCCarbapenam-3-carboxylate synthase6.3.3.60.440
1trgCB3Thymidylate synthase/0.440
1u7tNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.440
1ycgFMNNitric oxide reductase10.440
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.440
2ed3SAHDiphthine synthase/0.440
2gjnFMNNitronate monooxygenase1.13.12.160.440
2hg1N5OEndoplasmin/0.440
2w02ATPAcsD/0.440
2x06NADL-sulfolactate dehydrogenase/0.440
2x9dITCTetracycline repressor protein class D/0.440
2yj4ATPCopper-transporting ATPase/0.440
2zbaZBATrichothecene 3-O-acetyltransferase/0.440
3aosJH2Hemolymph juvenile hormone binding protein/0.440
3d8vUD1Bifunctional protein GlmU/0.440
3hnzPMN3-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.440
3p1799PProthrombin3.4.21.50.440
3rdqDTBStreptavidin/0.440
4brdANPEctonucleoside triphosphate diphosphohydrolase I/0.440
4k5o1OTM1 family aminopeptidase3.4.110.440
4qaiFMNNADPH dehydrogenase/0.440
5fm7ADPRuvB-like helicase/0.440