sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1aku | FMN | Flavodoxin |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1aku | FMN | Flavodoxin | / | 1.000 | |
| 1j8q | FMN | Flavodoxin | / | 0.625 | |
| 2fx2 | FMN | Flavodoxin | / | 0.609 | |
| 1azl | FMN | Flavodoxin | / | 0.606 | |
| 4fx2 | FMN | Flavodoxin | / | 0.593 | |
| 1akr | FMN | Flavodoxin | / | 0.592 | |
| 1akw | FMN | Flavodoxin | / | 0.587 | |
| 1wsb | FMN | Flavodoxin | / | 0.578 | |
| 5tgz | FMN | Cannabinoid receptor 1 | / | 0.571 | |
| 3f6r | FMN | Flavodoxin | / | 0.570 | |
| 5fx2 | FMN | Flavodoxin | / | 0.564 | |
| 1c7f | FMN | Flavodoxin | / | 0.563 | |
| 1j9g | FMN | Flavodoxin | / | 0.563 | |
| 1fx1 | FMN | Flavodoxin | / | 0.560 | |
| 1bu5 | RBF | Flavodoxin | / | 0.548 | |
| 5xra | FMN | Cannabinoid receptor 1 | / | 0.546 | |
| 3kaq | FMN | Flavodoxin | / | 0.537 | |
| 2fcr | FMN | Flavodoxin | / | 0.529 | |
| 3kap | FMN | Flavodoxin | / | 0.522 | |
| 4y7c | FMN | NADPH--cytochrome P450 reductase | / | 0.521 | |
| 5xr8 | FMN | Cannabinoid receptor 1 | / | 0.511 | |
| 3ojx | FMN | NADPH--cytochrome P450 reductase | / | 0.510 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.500 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.494 | |
| 1ykg | FMN | Sulfite reductase [NADPH] flavoprotein alpha-component | / | 0.493 | |
| 3i8p | 840 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.493 | |
| 2a2c | ADP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.492 | |
| 4oxx | FMN | Cindoxin | / | 0.492 | |
| 1ahn | FMN | Flavodoxin 1 | / | 0.491 | |
| 1xyv | FMN | Flavodoxin | / | 0.491 | |
| 3ivc | FG4 | Pantothenate synthetase | 6.3.2.1 | 0.490 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.489 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.488 | |
| 3ggs | 2FD | Purine nucleoside phosphorylase | 2.4.2.1 | 0.488 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.487 | |
| 3hgo | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.487 | |
| 1ni1 | 2C5 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.484 | |
| 3ho2 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.484 | |
| 3qvi | K95 | HAP protein | / | 0.483 | |
| 4js0 | GNP | Cell division control protein 42 homolog | / | 0.482 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.481 | |
| 4du6 | GTP | GTP cyclohydrolase 1 | / | 0.481 | |
| 5erm | 210 | Fusicoccadiene synthase | 4.2.3.43 | 0.481 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.480 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.480 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.480 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.480 | |
| 1icq | OPD | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.479 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.479 | |
| 2mt9 | FMN | Flavodoxin 2 | / | 0.479 | |
| 1gpu | THD | Transketolase 1 | 2.2.1.1 | 0.478 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.478 | |
| 2ii6 | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.478 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.477 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.477 | |
| 4jtq | NAP | Aldo-keto reductase family 1 member C2 | / | 0.477 | |
| 2clm | F6F | Tryptophan synthase alpha chain | / | 0.476 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.476 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.476 | |
| 2mok | FMN | Flavodoxin 1 | / | 0.476 | |
| 4b1j | A1R | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.476 | |
| 4bj9 | UHB | Tankyrase-2 | 2.4.2.30 | 0.476 | |
| 5e5h | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.476 | |
| 2bdy | UNB | Prothrombin | 3.4.21.5 | 0.475 | |
| 2ejz | SAH | Diphthine synthase | / | 0.475 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.475 | |
| 3kjg | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.475 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.474 | |
| 2r8o | T5X | Transketolase 1 | / | 0.474 | |
| 3dzi | RGT | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.474 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.474 | |
| 4c72 | TLG | 3-oxoacyl-ACP synthase | / | 0.474 | |
| 2jf0 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.473 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.472 | |
| 3bgs | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.472 | |
| 4c71 | 7RD | 3-oxoacyl-ACP synthase | / | 0.472 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.472 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.471 | |
| 2gyu | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.471 | |
| 2msd | GNP | MHC class I alpha chain | / | 0.471 | |
| 3dop | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.471 | |
| 3fsj | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.471 | |
| 3qwp | SAM | Histone-lysine N-methyltransferase SMYD3 | 2.1.1.43 | 0.471 | |
| 4kp7 | 1UQ | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.471 | |
| 4xnw | 2ID | P2Y purinoceptor 1 | / | 0.471 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.470 | |
| 1xyy | FMN | Flavodoxin | / | 0.470 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.470 | |
| 3bbp | GTP | Ras-related protein Rab-6A | / | 0.470 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.470 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.470 | |
| 1ofv | FMN | Flavodoxin | / | 0.469 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.469 | |
| 2ok8 | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.469 | |
| 3nyt | ULP | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.469 | |
| 3ou2 | SAH | SAM-dependent methyltransferase | / | 0.469 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.469 | |
| 1cjk | FOK | Adenylate cyclase type 2 | / | 0.468 | |
| 1cjk | FOK | Adenylate cyclase type 5 | / | 0.468 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.468 | |
| 2r8p | T6F | Transketolase 1 | / | 0.468 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.468 | |
| 3juq | AJD | Phenazine biosynthesis protein A/B | / | 0.468 | |
| 4b7z | Q4Q | Acetylcholinesterase | 3.1.1.7 | 0.468 | |
| 4yfy | 0FX | VioF | / | 0.468 | |
| 1piw | NAP | NADP-dependent alcohol dehydrogenase 6 | 1.1.1.2 | 0.467 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.467 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.467 | |
| 3gr8 | FMN | NADPH dehydrogenase | / | 0.467 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.467 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.466 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.466 | |
| 1vgq | CAO | Formyl-CoA:oxalate CoA-transferase | / | 0.466 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.466 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.466 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.466 | |
| 2r5n | TPP | Transketolase 1 | / | 0.466 | |
| 3esy | FMN | Flavodoxin | / | 0.466 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.466 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.466 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.465 | |
| 3q8u | ADP | Nucleoside diphosphate kinase | / | 0.465 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.465 | |
| 4imf | SI3 | N-acetylneuraminate lyase | / | 0.465 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.464 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.464 | |
| 2q92 | B23 | Methionine aminopeptidase | / | 0.464 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.464 | |
| 4b1h | AR6 | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.464 | |
| 1gw2 | FER | Peroxidase C1A | 1.11.1.7 | 0.463 | |
| 1jwt | BLI | Prothrombin | 3.4.21.5 | 0.463 | |
| 1pwy | AC2 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.463 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.463 | |
| 2gby | BRN | HTH-type transcriptional regulator QacR | / | 0.463 | |
| 2rd2 | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.463 | |
| 2v13 | C40 | Renin | 3.4.23.15 | 0.463 | |
| 2zfr | 46U | Prothrombin | 3.4.21.5 | 0.463 | |
| 2zrx | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.463 | |
| 3dzk | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.463 | |
| 3n3a | FMN | Protein NrdI | / | 0.463 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.463 | |
| 4bis | 8HQ | Lysine-specific demethylase 4A | 1.14.11 | 0.463 | |
| 4e2d | FMN | Dehydrogenase | / | 0.463 | |
| 1czn | FMN | Flavodoxin | / | 0.462 | |
| 1jue | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.462 | |
| 2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.462 | |
| 3b05 | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.462 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.462 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.462 | |
| 4c73 | TLH | 3-oxoacyl-ACP synthase | / | 0.462 | |
| 4m5p | FMN | NADPH dehydrogenase | / | 0.462 | |
| 4tta | FMC | Purine nucleoside phosphorylase DeoD-type | / | 0.462 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.462 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.461 | |
| 1tco | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.461 | |
| 1tco | FK5 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | 3.1.3.16 | 0.461 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.461 | |
| 2bb3 | SAH | Cobalamin biosynthesis precorrin-6Y methylase (CbiE) | / | 0.461 | |
| 2y3p | SM8 | DNA gyrase subunit A | / | 0.461 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 3eks | CY9 | Actin-5C | / | 0.461 | |
| 3qwc | 98P | Prothrombin | 3.4.21.5 | 0.461 | |
| 3tg4 | SAM | N-lysine methyltransferase SMYD2 | / | 0.461 | |
| 4f32 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | / | 0.461 | |
| 4jt8 | 1NR | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.461 | |
| 4rnw | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.461 | |
| 1okl | MNS | Carbonic anhydrase 2 | 4.2.1.1 | 0.460 | |
| 1r2j | FAD | FkbI | / | 0.460 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 1w6j | R71 | Lanosterol synthase | 5.4.99.7 | 0.460 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.460 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.460 | |
| 3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.460 | |
| 3po6 | DT9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.460 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.460 | |
| 4j1c | 1HO | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 4lxa | 1YS | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 4n1g | CEI | Obelin | / | 0.460 | |
| 1h36 | R88 | Squalene--hopene cyclase | 4.2.1.129 | 0.459 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 2abj | PLP | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.459 | |
| 2e16 | SAH | Diphthine synthase | / | 0.459 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.459 | |
| 2v2z | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.459 | |
| 2zhf | 49U | Prothrombin | 3.4.21.5 | 0.459 | |
| 2zz0 | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.459 | |
| 3b05 | IPE | Isopentenyl-diphosphate delta-isomerase | / | 0.459 | |
| 3clu | FAD | Electron transfer flavoprotein subunit alpha | / | 0.459 | |
| 3mhp | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.459 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.459 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.458 | |
| 1ikg | REX | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.458 | |
| 1m4i | COA | Aminoglycoside 2'-N-acetyltransferase | 2.3.1 | 0.458 | |
| 1que | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.458 | |
| 1yhn | GTP | Ras-related protein Rab-7a | / | 0.458 | |
| 1z3c | SA8 | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.458 | |
| 2xvh | FAD | Putative flavin-containing monooxygenase | / | 0.458 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.458 | |
| 3ntr | NAD | Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase | 1.1.1.18 | 0.458 | |
| 3w5h | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.458 | |
| 4l1x | NAP | Aldo-keto reductase family 1 member C2 | / | 0.458 | |
| 4u3j | GTP | Tubulin beta chain | / | 0.458 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.458 | |
| 1mue | CDD | Prothrombin | 3.4.21.5 | 0.457 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.457 | |
| 2vet | UMP | Thymidylate synthase | / | 0.457 | |
| 2zev | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.457 | |
| 2zhe | 13U | Prothrombin | 3.4.21.5 | 0.457 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 3gam | MXX | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.457 | |
| 3hy9 | 098 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.457 | |
| 3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.457 | |
| 3mau | PLR | Putative sphingosine-1-phosphate lyase | / | 0.457 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.457 | |
| 4brg | GNP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.457 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.457 | |
| 1gg5 | E09 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.456 | |
| 1h69 | ARH | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.456 | |
| 1ppj | ANY | Cytochrome b | / | 0.456 | |
| 1tll | FMN | Nitric oxide synthase, brain | 1.14.13.39 | 0.456 | |
| 2aba | STR | Pentaerythritol tetranitrate reductase | / | 0.456 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.456 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.456 | |
| 2zi2 | 24U | Prothrombin | 3.4.21.5 | 0.456 | |
| 3igp | DT7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.456 | |
| 3wag | TYD | Glycosyltransferase | / | 0.456 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.456 | |
| 4qai | FMN | NADPH dehydrogenase | / | 0.456 | |
| 4u0s | ADP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.456 | |
| 4z0p | NDP | NAD-dependent dehydrogenase | / | 0.456 | |
| 1sdw | IYT | Peptidyl-glycine alpha-amidating monooxygenase | 1.14.17.3 | 0.455 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.455 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.455 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.455 | |
| 2zfq | 45U | Prothrombin | 3.4.21.5 | 0.455 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.455 | |
| 3cav | CI2 | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.455 | |
| 3e23 | SAM | Uncharacterized protein | / | 0.455 | |
| 3uax | NOS | Purine nucleoside phosphorylase DeoD-type | / | 0.455 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.455 | |
| 4iom | FOL | Formate--tetrahydrofolate ligase | / | 0.455 | |
| 4j0p | 1H8 | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 4zqc | F6F | Tryptophan synthase alpha chain | / | 0.455 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.454 | |
| 1fue | FMN | Flavodoxin | / | 0.454 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.454 | |
| 1kwc | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.454 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.454 | |
| 1t4v | 14A | Prothrombin | 3.4.21.5 | 0.454 | |
| 1v45 | 3DG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.454 | |
| 1wn3 | HXC | Phenylacetic acid degradation protein PaaI | / | 0.454 | |
| 2egl | SAH | Diphthine synthase | / | 0.454 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.454 | |
| 2qe2 | 452 | Polyprotein | / | 0.454 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.454 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.454 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.454 | |
| 3nt5 | NAI | Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase | 1.1.1.18 | 0.454 | |
| 3uwe | VJJ | Aldo-keto reductase family 1 member C3 | / | 0.454 | |
| 4eu4 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.454 | |
| 4l7v | SAH | Protein-L-isoaspartate O-methyltransferase | / | 0.454 | |
| 4u0z | APC | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.454 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.454 | |
| 4zj8 | SUV | Orexin receptor type 1 | / | 0.454 | |
| 1a26 | CNA | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.453 | |
| 1ix1 | BB2 | Peptide deformylase | / | 0.453 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.453 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.453 | |
| 1qk3 | 5GP | Hypoxanthine-guanine-xanthine phosphoribosyltransferase | 2.4.2.22 | 0.453 | |
| 1ri1 | GTG | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.453 | |
| 1vf2 | GTX | Glutathione S-transferase 3 | 2.5.1.18 | 0.453 | |
| 2fxu | BID | Actin, alpha skeletal muscle | / | 0.453 | |
| 2x1e | X1E | Acyl-coenzyme A:6-aminopenicillanic-acid-acyltransferase 40 kDa form | 2.3.1.164 | 0.453 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.453 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.453 | |
| 3hat | GLY_VAL_ARG_RNG | Prothrombin | 3.4.21.5 | 0.453 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.453 | |
| 3ojx | FAD | NADPH--cytochrome P450 reductase | / | 0.453 | |
| 3pn1 | IVH | DNA ligase | / | 0.453 | |
| 3u5y | SCG | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.453 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.453 | |
| 4drk | I63 | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.453 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.453 | |
| 1fdr | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.452 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.452 | |
| 1zgi | 382 | Prothrombin | 3.4.21.5 | 0.452 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 2dxd | ANP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.452 | |
| 2hv9 | SFG | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.452 | |
| 2xi4 | AFT | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 2xuj | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 3biy | 01K | Histone acetyltransferase p300 | / | 0.452 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.452 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.452 | |
| 3go4 | SAH | Uncharacterized protein | / | 0.452 | |
| 3hxd | BD7 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.452 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3mau | EXT | Putative sphingosine-1-phosphate lyase | / | 0.452 | |
| 4l09 | 1UR | Tankyrase-2 | 2.4.2.30 | 0.452 | |
| 1bjk | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.451 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 1gj4 | 132 | Prothrombin | 3.4.21.5 | 0.451 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.451 | |
| 1ta6 | 177 | Prothrombin | 3.4.21.5 | 0.451 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 1zgv | 501 | Prothrombin | 3.4.21.5 | 0.451 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.451 | |
| 2qmz | LDP | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.451 | |
| 2z4s | ADP | Chromosomal replication initiator protein DnaA | / | 0.451 | |
| 3iqi | ASN_GLU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.451 | |
| 3ld6 | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.451 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.451 | |
| 4biw | ANP | Sensor histidine kinase CpxA | / | 0.451 | |
| 4yfy | 1YJ | VioF | / | 0.451 | |
| 1ni1 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.450 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 1v35 | NAI | Enoyl-ACP reductase | / | 0.450 | |
| 1vf3 | GDN | Glutathione S-transferase 3 | 2.5.1.18 | 0.450 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.450 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.450 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.450 | |
| 2ejk | SAH | Diphthine synthase | / | 0.450 | |
| 2gna | GDU | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.450 | |
| 2hpv | FMN | FMN-dependent NADH-azoreductase | 1.7 | 0.450 | |
| 2ipi | AKY | Aclacinomycin-N/aclacinomycin-A oxidase | / | 0.450 | |
| 2nmt | MIM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.450 | |
| 2oc9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.450 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 2zfn | ACO | Histone acetyltransferase RTT109 | 2.3.1.48 | 0.450 | |
| 3aw9 | GDU | NAD-dependent epimerase/dehydratase | / | 0.450 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.450 | |
| 4a6n | FAD | TetX family tetracycline inactivation enzyme | / | 0.450 | |
| 4l4x | NDP | AmphI | / | 0.450 | |
| 4ycp | FMN | tRNA-dihydrouridine(16) synthase | / | 0.450 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.449 | |
| 1cbf | SAH | Cobalt-precorrin-4 C(11)-methyltransferase | 2.1.1.271 | 0.449 | |
| 1j9z | FMN | NADPH--cytochrome P450 reductase | / | 0.449 | |
| 1npd | NAD | Quinate/shikimate dehydrogenase | / | 0.449 | |
| 1tkc | M6T | Transketolase 1 | 2.2.1.1 | 0.449 | |
| 1yun | ATP | Probable nicotinate-nucleotide adenylyltransferase | 2.7.7.18 | 0.449 | |
| 2fhl | BNI | Avidin-related protein 4/5 | / | 0.449 | |
| 2gyw | OBI | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.449 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.449 | |
| 3h2s | NDP | Putative NADH-flavin reductase | / | 0.449 | |
| 3qbj | NXZ | Dipeptidyl peptidase 4 | / | 0.449 | |
| 3reo | SAH | (Iso)eugenol O-methyltransferase | 2.1.1.146 | 0.449 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.449 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.449 | |
| 4zvn | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.449 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.449 | |
| 4u14 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.449 | |
| 1b8n | IMG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.448 | |
| 1b8o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.448 | |
| 1cnf | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.448 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.448 | |
| 1r5g | AO1 | Methionine aminopeptidase 2 | / | 0.448 | |
| 1t4u | 81A | Prothrombin | 3.4.21.5 | 0.448 | |
| 1tdu | CB3 | Thymidylate synthase | / | 0.448 | |
| 1z71 | L17 | Prothrombin | 3.4.21.5 | 0.448 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.448 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.448 | |
| 2bdz | E64 | Mexicain | 3.4.22 | 0.448 | |
| 2e8r | SAH | Diphthine synthase | / | 0.448 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.448 | |
| 2gcg | NDP | Glyoxylate reductase/hydroxypyruvate reductase | 1.1.1.79 | 0.448 | |
| 2gfx | PMN | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.448 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.448 | |
| 2r2m | I50 | Prothrombin | 3.4.21.5 | 0.448 | |
| 2vb8 | TLM | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.448 | |
| 2wge | TLM | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.448 | |
| 2x6o | 2TC | Tetracycline repressor protein class D | / | 0.448 | |
| 3hyg | 099 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.448 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3m2y | BE0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.448 | |
| 3nx2 | FER | Ferulic acid decarboxylase | / | 0.448 | |
| 3pke | Y10 | Methionine aminopeptidase 2 | / | 0.448 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.448 | |
| 3r5y | F42 | Uncharacterized protein | / | 0.448 | |
| 3sfh | 1DI | Histone deacetylase 8 | 3.5.1.98 | 0.448 | |
| 3w0t | HPU | Lactoylglutathione lyase | 4.4.1.5 | 0.448 | |
| 4fui | UI3 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.448 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.448 | |
| 3vw7 | VPX | Proteinase-activated receptor 1 | / | 0.448 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 1jf0 | CZH | Obelin | / | 0.447 | |
| 1p91 | SAM | 23S rRNA (guanine(745)-N(1))-methyltransferase | / | 0.447 | |
| 1q45 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.447 | |
| 1r6u | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.447 | |
| 1tka | N3T | Transketolase 1 | 2.2.1.1 | 0.447 | |
| 1vce | SAH | Diphthine synthase | / | 0.447 | |
| 1yci | NDF | Hypoxia-inducible factor 1-alpha inhibitor | 1.14.11.30 | 0.447 | |
| 2dsh | SAH | Diphthine synthase | / | 0.447 | |
| 2fap | RAD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.447 | |
| 2fap | RAD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.447 | |
| 2v2z | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.447 | |
| 2v9c | MRE | FMN-dependent NADH-azoreductase 1 | / | 0.447 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.447 | |
| 2zs8 | ADP | Pantothenate kinase | 2.7.1.33 | 0.447 | |
| 3d4b | DZD | NAD-dependent protein deacetylase | / | 0.447 | |
| 3g1r | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.447 | |
| 3o7b | SAH | Ribosomal RNA small subunit methyltransferase Nep1 | / | 0.447 | |
| 3opm | LUI | Dipeptidyl peptidase 4 | / | 0.447 | |
| 3r9f | GSU | MccE protein | / | 0.447 | |
| 3sfy | 3FY | Uncharacterized protein | / | 0.447 | |
| 4b1c | 1B1 | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4lnb | ED5 | CaaX farnesyltransferase beta subunit Ram1 | / | 0.447 | |
| 4mv8 | ACP | Biotin carboxylase | 6.3.4.14 | 0.447 | |
| 4x9d | U5P | Uncharacterized protein MJ1435 | / | 0.447 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.446 | |
| 1f8s | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.446 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.446 | |
| 1lvu | 9PP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.446 | |
| 1owd | 497 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.446 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 1x2e | ATX | Proline iminopeptidase | 3.4.11.5 | 0.446 | |
| 1zis | INI | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.446 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 2e8h | SAH | Diphthine synthase | / | 0.446 | |
| 2ed4 | NAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.446 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.446 | |
| 2jgs | BTN | Avidin | / | 0.446 | |
| 2nmt | NHM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.446 | |
| 2op1 | 8PC | Enoyl-ACP reductase | / | 0.446 | |
| 2wmd | ZZ0 | NmrA-like family domain-containing protein 1 | / | 0.446 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.446 | |
| 2wzy | SQX | Soluble acetylcholine receptor | / | 0.446 | |
| 2z7h | GG3 | Geranylgeranyl pyrophosphate synthase | / | 0.446 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 3bi6 | 396 | Wee1-like protein kinase | 2.7.10.2 | 0.446 | |
| 3biz | 61E | Wee1-like protein kinase | 2.7.10.2 | 0.446 | |
| 3exf | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.446 | |
| 3exf | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.446 | |
| 3gb4 | D3M | DdmC | / | 0.446 | |
| 3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.446 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 3tne | RIT | Candidapepsin-1 | 3.4.23.24 | 0.446 | |
| 3v49 | PK0 | Androgen receptor | / | 0.446 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.446 | |
| 3vkj | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.446 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 4dpe | NGH | Stromelysin-1 | 3.4.24.17 | 0.446 | |
| 4g8c | C6L | Alpha/beta hydrolase fold protein | / | 0.446 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 4o9c | COA | Acetyl-CoA acetyltransferase | 2.3.1.9 | 0.446 | |
| 5dp2 | NAP | CurF | / | 0.446 | |
| 1az2 | NAP | Aldose reductase | 1.1.1.21 | 0.445 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.445 | |
| 1d3p | BT3 | Prothrombin | 3.4.21.5 | 0.445 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.445 | |
| 1mmk | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.445 | |
| 1mrk | FMC | Ribosome-inactivating protein alpha-trichosanthin | 3.2.2.22 | 0.445 | |
| 1std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.445 | |
| 1txz | APR | Probable ADP-ribose 1''-phosphate phosphatase YML087W | 3.1.3.84 | 0.445 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 1ycf | FMN | Nitric oxide reductase | 1 | 0.445 | |
| 2a2d | ANP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.445 | |
| 2ckm | AA7 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 2eh5 | SAH | Diphthine synthase | / | 0.445 | |
| 2eni | SAH | Diphthine synthase | / | 0.445 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 2v3h | I25 | Prothrombin | 3.4.21.5 | 0.445 | |
| 2xda | JPS | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.445 | |
| 3i1y | 33N | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.445 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3nuv | ASD | Steroid Delta-isomerase | 5.3.3.1 | 0.445 | |
| 3ufl | 508 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 3uku | C69 | Actin-related protein 3 | / | 0.445 | |
| 3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.445 | |
| 3zc3 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.445 | |
| 4bam | MM9 | Prothrombin | 3.4.21.5 | 0.445 | |
| 4d04 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.445 | |
| 4eph | 0RK | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.445 | |
| 4f0e | 0RU | Poly [ADP-ribose] polymerase 15 | 2.4.2.30 | 0.445 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 4js1 | CTN | Beta-galactoside alpha-2,6-sialyltransferase 1 | 2.4.99.1 | 0.445 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.445 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.445 | |
| 3uon | QNB | Muscarinic acetylcholine receptor M2 | / | 0.445 | |
| 1c5n | ESI | Prothrombin | 3.4.21.5 | 0.444 | |
| 1kt8 | ILP | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.444 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.444 | |
| 1p4a | PCP | Pur operon repressor | / | 0.444 | |
| 1ri4 | SAM | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.444 | |
| 1sg0 | STL | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.444 | |
| 1vot | HUP | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.444 | |
| 1xp8 | AGS | Protein RecA | / | 0.444 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.444 | |
| 2ob0 | ACO | N-alpha-acetyltransferase 50 | / | 0.444 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.444 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.444 | |
| 2xuf | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.444 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.444 | |
| 3eft | 3BS | Carbonic anhydrase 2 | 4.2.1.1 | 0.444 | |
| 3jqr | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.444 | |
| 3ndj | JHZ | Methyltransferase | / | 0.444 | |
| 3qgi | 33F | Genome polyprotein | 2.7.7.48 | 0.444 | |
| 3zj7 | C1K | Strictosidine-O-beta-D-glucosidase | 3.2.1.105 | 0.444 | |
| 4ban | M6S | Prothrombin | 3.4.21.5 | 0.444 | |
| 4bri | UNP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.444 | |
| 4gv7 | MEW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.444 | |
| 4hrq | AZG | Cytidine and deoxycytidylate deaminase zinc-binding region | / | 0.444 | |
| 4hyv | PEP | Pyruvate kinase 1 | 2.7.1.40 | 0.444 | |
| 4i1c | 1BE | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4k9o | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.444 | |
| 4m49 | 22Y | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.444 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.444 | |
| 4rri | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.444 | |
| 1a8p | FAD | Ferredoxin--NADP reductase | / | 0.443 | |
| 1emd | NAD | Malate dehydrogenase | / | 0.443 | |
| 1gjr | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.443 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.443 | |
| 1pr4 | MTP | Purine nucleoside phosphorylase DeoD-type | / | 0.443 | |
| 1rsg | FAD | Polyamine oxidase FMS1 | / | 0.443 | |
| 1xva | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.443 | |
| 2c4f | GIL | Coagulation factor VII | 3.4.21.21 | 0.443 | |
| 2emu | SAH | Diphthine synthase | / | 0.443 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 2wd8 | VGF | Pteridine reductase | / | 0.443 | |
| 2xuq | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 2yig | 5EL | Collagenase 3 | 3.4.24 | 0.443 | |
| 2zs9 | ADP | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3faz | NOS | Purine nucleoside phosphorylase | / | 0.443 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.443 | |
| 3qgf | 46F | Genome polyprotein | 2.7.7.48 | 0.443 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.443 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 4emd | C5P | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.443 | |
| 1dc6 | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.442 | |
| 1eje | FMN | Protein MTH_152 | / | 0.442 | |
| 1fw0 | KAI | Glutamate receptor 2 | / | 0.442 | |
| 1k27 | MTM | S-methyl-5'-thioadenosine phosphorylase | / | 0.442 | |
| 1lv8 | 9PP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
| 1nzy | BCA | 4-chlorobenzoyl coenzyme A dehalogenase | 3.8.1.7 | 0.442 | |
| 1pr1 | FMB | Purine nucleoside phosphorylase DeoD-type | / | 0.442 | |
| 1qrs | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.442 | |
| 1qtq | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.442 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.442 | |
| 1xzq | FON | tRNA modification GTPase MnmE | 3.6.5 | 0.442 | |
| 2aq7 | TL5 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.442 | |
| 2cnd | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.442 | |
| 2ffq | GSP | Ras-related protein Rab-6B | / | 0.442 | |
| 2ji9 | TPW | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.442 | |
| 2owg | SAH | Diphthine synthase | / | 0.442 | |
| 2pgt | GPR | Glutathione S-transferase P | 2.5.1.18 | 0.442 | |
| 2pks | G44 | Prothrombin | 3.4.21.5 | 0.442 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.442 | |
| 2wwj | Y28 | Lysine-specific demethylase 4A | / | 0.442 | |
| 2xb9 | XNW | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.442 | |
| 2zvb | SAH | Precorrin-3 C17-methyltransferase | / | 0.442 | |
| 3c72 | CX1 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.442 | |
| 3fql | 79Z | Genome polyprotein | 2.7.7.48 | 0.442 | |
| 3i6q | NDP | Putative leucoanthocyanidin reductase 1 | / | 0.442 | |
| 3pld | F90 | Endothiapepsin | 3.4.23.22 | 0.442 | |
| 3rk1 | ATP | N-type ATP pyrophosphatase superfamily | / | 0.442 | |
| 3vr8 | RQX | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | / | 0.442 | |
| 3vr8 | RQX | Cytochrome b-large subunit | / | 0.442 | |
| 4b68 | NAP | L-ornithine N(5)-monooxygenase | / | 0.442 | |
| 4c6z | TLE | 3-oxoacyl-ACP synthase | / | 0.442 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.442 | |
| 4glx | 0XS | DNA ligase | 6.5.1.2 | 0.442 | |
| 4i4b | 1CV | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.442 | |
| 4jic | FMN | GTN Reductase | / | 0.442 | |
| 4lol | 1YE | Stimulator of interferon genes protein | / | 0.442 | |
| 4rel | KMP | Glycosyltransferase | / | 0.442 | |
| 4wuo | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.442 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.441 | |
| 1kw6 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.441 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1o97 | FAD | Electron transfer flavoprotein subunit alpha | / | 0.441 | |
| 1rp0 | AHZ | Thiamine thiazole synthase, chloroplastic | / | 0.441 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 1sb1 | 165 | Prothrombin | 3.4.21.5 | 0.441 | |
| 1w4l | GL8 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.441 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 2fb3 | 5AD | GTP 3',8-cyclase | 4.1.99.18 | 0.441 | |
| 2fhj | H4Z | Formylmethanofuran--tetrahydromethanopterin formyltransferase | 2.3.1.101 | 0.441 | |
| 2onf | COA | Uncharacterized protein | / | 0.441 | |
| 2owk | SAH | Diphthine synthase | / | 0.441 | |
| 2p4s | DIH | AGAP005945-PA | / | 0.441 | |
| 2vq7 | NAP | Putative flavin-containing monooxygenase | / | 0.441 | |
| 2ydb | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.441 | |
| 3bxo | UPP | dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose | / | 0.441 | |
| 3dd8 | 2C7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.441 | |
| 3eg5 | GNP | Cell division control protein 42 homolog | / | 0.441 | |
| 3eku | CY9 | Actin-5C | / | 0.441 | |
| 3imx | B84 | Glucokinase | 2.7.1.2 | 0.441 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 3mz9 | BHN | Nickel-binding periplasmic protein | / | 0.441 | |
| 3nn6 | HNK | 6-hydroxy-L-nicotine oxidase | / | 0.441 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.441 | |
| 3q33 | ACO | Histone acetyltransferase RTT109 | 2.3.1.48 | 0.441 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.441 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 4c43 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.441 | |
| 4d96 | 5PA | D-cysteine desulfhydrase | / | 0.441 | |
| 4epq | 0RR | Poly(ADP-ribose) glycohydrolase | / | 0.441 | |
| 4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.441 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4nv1 | TYD | Formyl transferase | / | 0.441 | |
| 4u9y | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.441 | |
| 4y3r | F06 | Endothiapepsin | 3.4.23.22 | 0.441 | |
| 4y6u | UPG | Glucosyl-3-phosphoglycerate synthase | 2.4.1.266 | 0.441 | |
| 4z26 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.441 | |
| 5eio | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.441 | |
| 1dor | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.440 | |
| 1fyf | SSA | Threonine--tRNA ligase | 6.1.1.3 | 0.440 | |
| 1iay | AVG | 1-aminocyclopropane-1-carboxylate synthase 2 | 4.4.1.14 | 0.440 | |
| 1kw8 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.440 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.440 | |
| 1ypl | RA8 | Prothrombin | 3.4.21.5 | 0.440 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 2cv1 | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.440 | |
| 2fut | H1S | Heparin and heparin-sulfate lyase | / | 0.440 | |
| 2jh6 | 894 | Prothrombin | 3.4.21.5 | 0.440 | |
| 2oc4 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 2rd6 | 78P | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.440 | |
| 2v58 | LZJ | Biotin carboxylase | 6.3.4.14 | 0.440 | |
| 2vut | NAD | Nitrogen metabolite repression protein nmrA | / | 0.440 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3bi5 | FAD | Polyamine oxidase FMS1 | / | 0.440 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 3l5d | BDV | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 4b1d | 6TG | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4b63 | NAP | L-ornithine N(5)-monooxygenase | / | 0.440 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 4brd | ANP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.440 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.440 | |
| 4d89 | BXD | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4dri | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.440 | |
| 4dri | RAP | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.440 | |
| 4jnk | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.440 | |
| 4jq3 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.440 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.440 | |
| 4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.440 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.440 |