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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.11.000
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.624
4eutBX7Serine/threonine-protein kinase TBK12.7.11.10.595
4im01FVSerine/threonine-protein kinase TBK12.7.11.10.582
4im2BX7Serine/threonine-protein kinase TBK12.7.11.10.567
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.554
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.552
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.550
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.547
4hvi19STyrosine-protein kinase JAK32.7.10.20.547
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.546
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.543
3qd33Q53-phosphoinositide-dependent protein kinase 12.7.11.10.542
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.541
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.541
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.540
2in6839Wee1-like protein kinase2.7.10.20.538
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.536
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.535
2pvnP63Casein kinase II subunit alpha2.7.11.10.533
3qd03Q43-phosphoinositide-dependent protein kinase 12.7.11.10.533
3zewSTUEphrin type-B receptor 42.7.10.10.532
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.531
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.530
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.528
4ji91M3Tyrosine-protein kinase JAK2/0.528
4aqc88ATyrosine-protein kinase JAK2/0.527
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.526
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.525
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.523
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.522
4fv6E57Mitogen-activated protein kinase 12.7.11.240.521
4grb0XGCasein kinase II subunit alpha2.7.11.10.521
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.520
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.520
4ez50RSCyclin-dependent kinase 62.7.11.220.520
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.519
1m2pHNACasein kinase II subunit alpha2.7.11.10.518
3zh8C58Protein kinase C iota type2.7.11.130.515
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.514
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.514
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.513
2vv9IM9Cyclin-dependent kinase 22.7.11.220.513
3qcx3Q23-phosphoinositide-dependent protein kinase 12.7.11.10.513
5e8ySTUTGF-beta receptor type-22.7.11.300.513
2biyATP3-phosphoinositide-dependent protein kinase 12.7.11.10.512
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.512
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.511
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.510
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.509
3a62STURibosomal protein S6 kinase beta-12.7.11.10.508
3kn5ANPRibosomal protein S6 kinase alpha-52.7.11.10.508
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.508
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.508
2yn8STUEphrin type-B receptor 42.7.10.10.507
1aq1STUCyclin-dependent kinase 22.7.11.220.506
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.506
2ckeIQUDeath-associated protein kinase 2/0.506
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.506
3t8oATPRhodopsin kinase/0.506
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.506
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.506
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.505
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.505
3lpbNVBTyrosine-protein kinase JAK2/0.505
1bygSTUTyrosine-protein kinase CSK/0.504
1jklANPDeath-associated protein kinase 12.7.11.10.504
2b7aIZATyrosine-protein kinase JAK2/0.504
2vtqLZACyclin-dependent kinase 22.7.11.220.503
3be9P04Casein kinase II subunit alpha2.7.11.10.503
3orzBI43-phosphoinositide-dependent protein kinase 12.7.11.10.503
4jia1K3Tyrosine-protein kinase JAK2/0.503
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.503
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.503
3pxkPXKFocal adhesion kinase 12.7.10.20.502
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.502
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.501
1yvj4STTyrosine-protein kinase JAK32.7.10.20.501
2w05FRTCyclin-dependent kinase 22.7.11.220.501
3i60E86Mitogen-activated protein kinase 12.7.11.240.501
3rvg17PTyrosine-protein kinase JAK2/0.501
1eh4IC1Casein kinase I homolog 12.7.11.10.500
2yaaATPDeath-associated protein kinase 2/0.500
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.500
4ivb1J5Tyrosine-protein kinase JAK1/0.500
4j95ACPFibroblast growth factor receptor 2/0.500
4j99ACPFibroblast growth factor receptor 2/0.500
4mq12C3Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.500
3q9xEMOCasein kinase II subunit alpha2.7.11.10.499
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.499
1m2rMNYCasein kinase II subunit alpha2.7.11.10.498
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.498
2pvmP29Casein kinase II subunit alpha2.7.11.10.498
4btjATPTau-tubulin kinase 12.7.11.10.498
2j0m4STFocal adhesion kinase 12.7.10.20.497
3zep1NXTyrosine-protein kinase JAK32.7.10.20.497
4ekl0RFRAC-alpha serine/threonine-protein kinase2.7.11.10.497
4f081RSTyrosine-protein kinase JAK2/0.497
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.496
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.496
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.496
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.495
4aguD15Cyclin-dependent kinase-like 1/0.495
4ct2ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.495
4hge15VTyrosine-protein kinase JAK2/0.495
4hgs15GCasein kinase I isoform gamma-32.7.11.10.495
4hvh19RTyrosine-protein kinase JAK32.7.10.20.495
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.494
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.494
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.494
4o0wADNAurora kinase A2.7.11.10.494
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.493
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.493
4dgnLU2Casein kinase II subunit alpha2.7.11.10.493
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.493
4gmy0X5Tyrosine-protein kinase JAK2/0.493
4oh4ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.493
2w17I19Cyclin-dependent kinase 22.7.11.220.492
3gxlQIGTGF-beta receptor type-12.7.11.300.492
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.492
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.492
5av2KMPDeath-associated protein kinase 12.7.11.10.492
1fvv107Cyclin-dependent kinase 22.7.11.220.491
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.491
3eb0DRKUncharacterized protein/0.491
3ggfGVDSerine/threonine-protein kinase 26/0.491
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.491
5dnrATPAurora kinase A2.7.11.10.491
1z5mLI83-phosphoinositide-dependent protein kinase 12.7.11.10.490
2pe039Z3-phosphoinositide-dependent protein kinase 12.7.11.10.490
2qo9ANPEphrin type-A receptor 32.7.10.10.490
2zv2609Calcium/calmodulin-dependent protein kinase kinase 22.7.11.170.490
3nux3NVCyclin-dependent kinase 62.7.11.220.490
4fkv61KCyclin-dependent kinase 22.7.11.220.490
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.490
1uu7BI23-phosphoinositide-dependent protein kinase 12.7.11.10.489
2vttLZDCyclin-dependent kinase 22.7.11.220.489
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.489
4anmWULCasein kinase II subunit alpha2.7.11.10.489
4bcmT7ZCyclin-dependent kinase 22.7.11.220.489
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.488
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.488
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.488
4fob0USALK tyrosine kinase receptor2.7.10.10.488
1mruAGSSerine/threonine-protein kinase PknB2.7.11.10.487
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.487
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.487
3rak03ZCyclin-dependent kinase 22.7.11.220.486
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.486
4hvg19QTyrosine-protein kinase JAK32.7.10.20.486
4i5cC5ITyrosine-protein kinase JAK1/0.486
5dt3ATPAurora kinase A2.7.11.10.486
1x8b824Wee1-like protein kinase2.7.10.20.485
2henADPEphrin type-B receptor 22.7.10.10.485
4jqeANPCasein kinase II subunit alpha2.7.11.10.485
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.484
1zrzBI1Protein kinase C iota type2.7.11.130.484
2vn9GVDCalcium/calmodulin-dependent protein kinase type II subunit delta2.7.11.170.484
2xa4AZ5Tyrosine-protein kinase JAK2/0.484
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.484
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.483
4awiAQ2Mitogen-activated protein kinase 82.7.11.240.483
4e6d0NUTyrosine-protein kinase JAK2/0.483
1u54ACPActivated CDC42 kinase 1/0.482
1wvxBD4Death-associated protein kinase 12.7.11.10.482
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.482
3sheI85MAP kinase-activated protein kinase 32.7.11.10.482
4e4n0NLTyrosine-protein kinase JAK1/0.482
4fv5EK9Mitogen-activated protein kinase 12.7.11.240.482
4rqvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.482
5cvfATPCasein kinase II subunit alpha2.7.11.10.482
1wvySTUDeath-associated protein kinase 12.7.11.10.481
2izuP01Casein kinase I isoform gamma-32.7.11.10.481
2pvhP19Casein kinase II subunit alpha2.7.11.10.481
3nuyJPZ3-phosphoinositide-dependent protein kinase 12.7.11.10.481
3r71X86Cyclin-dependent kinase 22.7.11.220.481
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.481
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.481
4fv1EK4Mitogen-activated protein kinase 12.7.11.240.481
5e92ANPTGF-beta receptor type-22.7.11.300.481
2fvdLIACyclin-dependent kinase 22.7.11.220.480
3nuuJOZ3-phosphoinositide-dependent protein kinase 12.7.11.10.480
4ix6ADPUncharacterized protein/0.480
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.479
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.479
2hog710Serine/threonine-protein kinase Chk12.7.11.10.479
2vu3LZECyclin-dependent kinase 22.7.11.220.479
4fg9ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.479
4jr7GNPCasein kinase II subunit alpha2.7.11.10.479
4l9i8PRRhodopsin kinase/0.479
4qnyANPMitogen activated protein kinase, putative/0.479
4enyJ19Serine/threonine-protein kinase pim-12.7.11.10.478
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.478
4wkqIREEpidermal growth factor receptor2.7.10.10.478
1j1bANPGlycogen synthase kinase-3 beta2.7.11.260.477
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.477
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.477
2dwbANPAurora kinase A2.7.11.10.477
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.477
3bqr4RBDeath-associated protein kinase 3/0.477
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.477
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.477
4fv3EK6Mitogen-activated protein kinase 12.7.11.240.477
4y95746Tyrosine-protein kinase/0.477
2csnCKICasein kinase I homolog 12.7.11.10.476
2h96893Mitogen-activated protein kinase 82.7.11.240.476
2xb7GUIALK tyrosine kinase receptor2.7.10.10.476
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.476
3u4uLNHCasein kinase II subunit alpha2.7.11.10.476
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.476
4fv2EK5Mitogen-activated protein kinase 12.7.11.240.476
1om1IQACasein kinase II subunit alpha2.7.11.10.475
1q3dSTUGlycogen synthase kinase-3 beta2.7.11.260.475
2a5uQYTPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.475
2eufLQQCyclin-dependent kinase 62.7.11.220.475
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.475
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.475
4c62XWWTyrosine-protein kinase JAK2/0.475
4fmqANPMitogen-activated protein kinase 12.7.11.240.475
2gu8796cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.474
2uzbC75Cyclin-dependent kinase 22.7.11.220.474
3hmm855TGF-beta receptor type-12.7.11.300.474
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.474
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.474
4jik1KOSerine/threonine-protein kinase Chk12.7.11.10.474
1uu8BI13-phosphoinositide-dependent protein kinase 12.7.11.10.473
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.473
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.473
3eyhIZATyrosine-protein kinase JAK1/0.473
3hx4ANPCalmodulin-domain protein kinase 1/0.473
5auvAGIDeath-associated protein kinase 12.7.11.10.473
5dr9SKEAurora kinase A2.7.11.10.473
1py5PY1TGF-beta receptor type-12.7.11.300.472
3at4CCKCasein kinase II subunit alpha2.7.11.10.472
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.472
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.472
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.472
4ic7ANPMitogen-activated protein kinase 72.7.11.240.472
1pkdUCNCyclin-dependent kinase 22.7.11.220.471
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.471
2x6dX6DAurora kinase A2.7.11.10.471
3rmf20ZCyclin-dependent kinase 22.7.11.220.471
3s1h56ZCyclin-dependent kinase 22.7.11.220.471
4mvfSTUCalcium-dependent protein kinase 22.7.11.10.471
4y93746Tyrosine-protein kinase/0.471
5dt0SKEAurora kinase A2.7.11.10.471
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.470
1q97ATPSerine/threonine-protein kinase SKY12.7.11.10.470
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.470
3igoANPCalmodulin-domain protein kinase 1, putative/0.470
3umw596Serine/threonine-protein kinase pim-12.7.11.10.470
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.470
4g1wG1WMitogen-activated protein kinase 82.7.11.240.470
1q3wATUGlycogen synthase kinase-3 beta2.7.11.260.469
1v1k3FPCyclin-dependent kinase 22.7.11.220.469
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.469
2ycfYCFSerine/threonine-protein kinase Chk22.7.11.10.469
3iok1P6Tyrosine-protein kinase JAK2/0.469
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.469
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.469
1csnATPCasein kinase I homolog 12.7.11.10.468
2ijmADPFocal adhesion kinase 12.7.10.20.468
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.468
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.468
3bhh5CPCalcium/calmodulin-dependent protein kinase type II subunit beta2.7.11.170.468
3biz61EWee1-like protein kinase2.7.10.20.468
4acdGR9Glycogen synthase kinase-3 beta2.7.11.260.468
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.468
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.468
5av3KMPDeath-associated protein kinase 12.7.11.10.468
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.467
3c4xATPRhodopsin kinase/0.467
4a9uA9USerine/threonine-protein kinase Chk22.7.11.10.467
4r8qADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.467
1pjkANPCasein kinase II subunit alpha2.7.11.10.466
2qoqANPEphrin type-A receptor 32.7.10.10.466
2vd5BI8Myotonin-protein kinase2.7.11.10.466
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.466
3lcdBDYMacrophage colony-stimulating factor 1 receptor2.7.10.10.466
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.466
4ftn2HKSerine/threonine-protein kinase Chk12.7.11.10.466
4gk3L87Ephrin type-A receptor 32.7.10.10.466
4k33ACPFibroblast growth factor receptor 32.7.10.10.466
4o1pANPRibonuclease L/0.466
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.466
5auwQUEDeath-associated protein kinase 12.7.11.10.466
5dmzADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.466
5dosATPAurora kinase A2.7.11.10.466
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.465
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.465
3le62BZCyclin-dependent kinase 22.7.11.220.465
4e4m0NHTyrosine-protein kinase JAK2/0.465
4e730NRMitogen-activated protein kinase 82.7.11.240.465
4ehzJAKTyrosine-protein kinase JAK1/0.465
4lrjANPUncharacterized protein/0.465
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.465
4riyADPEpidermal growth factor receptor2.7.10.10.465
5av4GENDeath-associated protein kinase 12.7.11.10.465
1v0oINRCell division control protein 2 homolog2.7.11.220.464
2izsBRQCasein kinase I isoform gamma-32.7.11.10.464
2j0lANPFocal adhesion kinase 12.7.10.20.464
2uztSS3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.464
3eljGS7Mitogen-activated protein kinase 82.7.11.240.464
4btjADPTau-tubulin kinase 12.7.11.10.464
4qmpDKISerine/threonine-protein kinase 242.7.11.10.464
4xf7ACPCarbohydrate/pyrimidine kinase, PfkB family/0.464
4yhjAN2G protein-coupled receptor kinase 42.7.11.160.464
5dpvSKEAurora kinase A2.7.11.10.464
1dawANPCasein kinase II subunit alpha2.7.11.10.463
1gii1PUCyclin-dependent kinase 22.7.11.220.463
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.463
2p33J07Mitogen-activated protein kinase 102.7.11.240.463
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.463
3cgfJNFMitogen-activated protein kinase 102.7.11.240.463
3lxkMI1Tyrosine-protein kinase JAK32.7.10.20.463
4fv9E71Mitogen-activated protein kinase 12.7.11.240.463
4j1rI5RGlycogen synthase kinase-3 beta2.7.11.260.463
4mf129YTyrosine-protein kinase ITK/TSK2.7.10.20.463
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.463
3vf80JETyrosine-protein kinase SYK2.7.10.20.462
4fg8ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.462
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.462
4qnaX11Serine/threonine-protein kinase 242.7.11.10.462
2f7e2EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.461
2izrBRKCasein kinase I isoform gamma-32.7.11.10.461
2uxpCLMHTH-type transcriptional regulator TtgR/0.461
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.461
3zmmF9JTyrosine-protein kinase JAK2/0.461
4wsqKSAAP2-associated protein kinase 12.7.11.10.461
2pvlP55Casein kinase II subunit alpha2.7.11.10.460
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.460
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.460
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.460
2xngA0HAurora kinase A2.7.11.10.460
3gubGUBDeath-associated protein kinase 12.7.11.10.460
3nynSGVG protein-coupled receptor kinase 62.7.11.160.460
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.460
5av047XDeath-associated protein kinase 12.7.11.10.460
1phgMYTCamphor 5-monooxygenase1.14.15.10.459
1snuSTUTyrosine-protein kinase ITK/TSK2.7.10.20.459
2b53D23Cyclin-dependent kinase 22.7.11.220.459
3cr0809Wee1-like protein kinase2.7.10.20.459
3cylVITBasic phospholipase A2 homolog piratoxin-2/0.459
3h86AP5Adenylate kinase/0.459
3ormAGSSerine/threonine protein kinase/0.459
3ral04ZCyclin-dependent kinase 22.7.11.220.459
3w2rW2REpidermal growth factor receptor2.7.10.10.459
4eok4SPCyclin-dependent kinase 22.7.11.220.459
4hgl0YOCasein kinase I isoform gamma-32.7.11.10.459
5cshATPCasein kinase II subunit alpha2.7.11.10.459
1ykr628Cyclin-dependent kinase 22.7.11.220.458
2c6o4SPCyclin-dependent kinase 22.7.11.220.458
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.458
2wipP49Cyclin-dependent kinase 22.7.11.220.458
2wtiWTISerine/threonine-protein kinase Chk22.7.11.10.458
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.458
3nbvANPKetohexokinase/0.458
3nwq2NCGag-Pol polyprotein3.4.23.160.458
3r9dX6BCyclin-dependent kinase 22.7.11.220.458
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.458
4dgo0JWCasein kinase II subunit alpha2.7.11.10.458
4fk60UJTyrosine-protein kinase JAK1/0.458
1u4dDBQActivated CDC42 kinase 1/0.457
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.457
2oj9BMIInsulin-like growth factor 1 receptor2.7.10.10.457
3dfcANPDeath-associated protein kinase 12.7.11.10.457
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.457
4dt9GMPAPH(2'')-Id/0.457
4e6q0NVTyrosine-protein kinase JAK2/0.457
4q5hANPProtein kinase OspG2.70.457
4wboANWRhodopsin kinase/0.457
5auxKMPDeath-associated protein kinase 12.7.11.10.457
2cchATPCyclin-dependent kinase 22.7.11.220.456
2wmrZYRSerine/threonine-protein kinase Chk12.7.11.10.456
3lltANPProtein serine/threonine kinase-1/0.456
3ncz3NCRho-associated protein kinase 12.7.11.10.456
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.456
4dtaADNAPH(2'')-Id/0.456
4ftq4HKSerine/threonine-protein kinase Chk12.7.11.10.456
4i0s1B5Tyrosine-protein kinase SYK2.7.10.20.456
4ifcADPSerine/threonine-protein kinase PRP4 homolog2.7.11.10.456
4iva1J5Tyrosine-protein kinase JAK2/0.456
4k771Q4Tyrosine-protein kinase JAK1/0.456
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.456
4qo9627Serine/threonine-protein kinase 242.7.11.10.456
5dr6SKEAurora kinase A2.7.11.10.456
1pmn984Mitogen-activated protein kinase 102.7.11.240.455
1zeoC01Peroxisome proliferator-activated receptor gamma/0.455
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.455
2c6iDT1Cyclin-dependent kinase 22.7.11.220.455
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.455
2eb3ANPEpidermal growth factor receptor2.7.10.10.455
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.455
2uw0GVKcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.455
2zjwREFCasein kinase II subunit alpha2.7.11.10.455
3gobHXXDdmC/0.455
3nieANPMitogen-activated protein kinase/0.455
3qtrX36Cyclin-dependent kinase 22.7.11.220.455
3rni21ZCyclin-dependent kinase 22.7.11.220.455
4iwd1JCHepatocyte growth factor receptor2.7.10.10.455
4tuvCPZCytochrome P450 1191.140.455
1k6pXN3Gag-Pol polyprotein3.4.23.160.454
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.454
2iw84SPCyclin-dependent kinase 22.7.11.220.454
2w1fL0FAurora kinase A2.7.11.10.454
2z7qACPRibosomal protein S6 kinase alpha-12.7.11.10.454
3my5RFZCyclin-dependent kinase 22.7.11.220.454
4bfvZVVPantothenate kinase2.7.1.330.454
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.454
4fad0TBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.454
4lfiGNPCasein kinase II subunit alpha2.7.11.10.454
4nka2K7Fibroblast growth factor receptor 1/0.454
1q99ANPSerine/threonine-protein kinase SKY12.7.11.10.453
1xjdSTUProtein kinase C theta type2.7.11.130.453
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.453
2w06FRVCyclin-dependent kinase 22.7.11.220.453
2x1nX1NCyclin-dependent kinase 22.7.11.220.453
2xyuQ9GEphrin type-A receptor 42.7.10.10.453
2zdt46CMitogen-activated protein kinase 102.7.11.240.453
3at3ATKCasein kinase II subunit alpha2.7.11.10.453
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.453
3h6vNS6Glutamate receptor 2/0.453
3lj3WYEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
3rkb12ZCyclin-dependent kinase 22.7.11.220.453
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
4dymIYZActivin receptor type-12.7.11.300.453
4f4p0SBTyrosine-protein kinase SYK2.7.10.20.453
4h3qANPMitogen-activated protein kinase 12.7.11.240.453
4w9wYDJBMP-2-inducible protein kinase2.7.11.10.453
5dn3ATPAurora kinase A2.7.11.10.453
5e8wSTUTGF-beta receptor type-12.7.11.300.453
1rfvADPPyridoxal kinase2.7.1.350.452
2r3jSCJCyclin-dependent kinase 22.7.11.220.452
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.452
2wmxZY6Serine/threonine-protein kinase Chk12.7.11.10.452
2xs0ANPMitogen-activated protein kinase 82.7.11.240.452
3gu7ADPDeath-associated protein kinase 12.7.11.10.452
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
4c57FEFCyclin-G-associated kinase2.7.11.10.452
4erwSTUCyclin-dependent kinase 22.7.11.220.452
4fx360KCyclin-dependent kinase 22.7.11.220.452
4gk2L66Ephrin type-A receptor 32.7.10.10.452
4gub0Y4Casein kinase II subunit alpha2.7.11.10.452
4j98ACPFibroblast growth factor receptor 2/0.452
5drdATPAurora kinase A2.7.11.10.452
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.451
2a0cCK9Cyclin-dependent kinase 22.7.11.220.451
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.451
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.451
2z2w770Wee1-like protein kinase2.7.10.20.451
3bhy7CPDeath-associated protein kinase 3/0.451
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.451
3s4qNK0Mitogen-activated protein kinase 14/0.451
3tnwF18Cyclin-dependent kinase 22.7.11.220.451
3w2sW2REpidermal growth factor receptor2.7.10.10.451
3zuxTCHTransporter/0.451
4bbfO19Tyrosine-protein kinase JAK2/0.451
4c61LMMTyrosine-protein kinase JAK2/0.451
4l7f1V5Mitogen-activated protein kinase 82.7.11.240.451
4qpmADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.451
1e9hINRCyclin-dependent kinase 22.7.11.220.450
1jioDEB6-deoxyerythronolide B hydroxylase/0.450
1oiyN41Cyclin-dependent kinase 22.7.11.220.450
1ol5ADPAurora kinase A2.7.11.10.450
1ppm0P1Penicillopepsin-13.4.23.200.450
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.450
2g226IGRenin3.4.23.150.450
2itqITQEpidermal growth factor receptor2.7.10.10.450
2xf04UBSerine/threonine-protein kinase Chk12.7.11.10.450
2yac937Serine/threonine-protein kinase PLK12.7.11.210.450
3a4vNADNDP-sugar epimerase/0.450
3oroAGSSerine/threonine protein kinase/0.450
3tdvGDPGentamicin resistance protein/0.450
3zw3ZW3Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
4deeADPAurora kinase A2.7.11.10.450
4dpuAGSMevalonate diphosphate decarboxylase/0.450
1k6tXN1Gag-Pol polyprotein3.4.23.160.449
1q8yADPSerine/threonine-protein kinase SKY12.7.11.10.449
1uu3LY43-phosphoinositide-dependent protein kinase 12.7.11.10.449
1ydrIQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.449
2c6lDT4Cyclin-dependent kinase 22.7.11.220.449
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.449
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.449
2y6o1N1Ephrin type-A receptor 42.7.10.10.449
3nszANPCasein kinase II subunit alpha2.7.11.10.449
3pe2E1BCasein kinase II subunit alpha2.7.11.10.449
3sd0TSKGlycogen synthase kinase-3 beta2.7.11.260.449
4e5w0NTTyrosine-protein kinase JAK1/0.449
4ftaH5KSerine/threonine-protein kinase Chk12.7.11.10.449
4mf029ZTyrosine-protein kinase ITK/TSK2.7.10.20.449
5cnoANPEpidermal growth factor receptor2.7.10.10.449
1bxqPP8Penicillopepsin-13.4.23.200.448
1cdeGARPhosphoribosylglycinamide formyltransferase/0.448
1ig1ANPDeath-associated protein kinase 12.7.11.10.448
1ny3ADPMAP kinase-activated protein kinase 22.7.11.10.448
1yjqNAP2-dehydropantoate 2-reductase1.1.1.1690.448
2gnhH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.448
2uzdC85Cyclin-dependent kinase 22.7.11.220.448
2x2lX2LProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.448
2xx91NFGlutamate receptor 2/0.448
3gu6ADPDeath-associated protein kinase 12.7.11.10.448
3sqq99ZCyclin-dependent kinase 22.7.11.220.448
3umpATPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.448
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.448
5auzGENDeath-associated protein kinase 12.7.11.10.448
1rw8580TGF-beta receptor type-12.7.11.300.447
2bxmIMNSerum albumin/0.447
2gnfY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
3gc9B45Mitogen-activated protein kinase 112.7.11.240.447
3otuBI43-phosphoinositide-dependent protein kinase 12.7.11.10.447
3s2a2NQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
3we45FIRibosomal protein S6 kinase beta-12.7.11.10.447
4b99R4LMitogen-activated protein kinase 72.7.11.240.447
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.447
4eh60ONMitogen-activated protein kinase 14/0.447
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.447
4ivd15TTyrosine-protein kinase JAK1/0.447
4jajXU1Aurora kinase A2.7.11.10.447
4kz01UJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
4oj4DIFPeroxisome proliferator-activated receptor gamma/0.447
4q72FADBifunctional protein PutA/0.447
4xj43ATCyclic GMP-AMP synthase/0.447
1g5sI17Cyclin-dependent kinase 22.7.11.220.446
1oi9N20Cyclin-dependent kinase 22.7.11.220.446
1qmzATPCyclin-dependent kinase 22.7.11.220.446
2qhn582Serine/threonine-protein kinase Chk12.7.11.10.446
2wecPP5Penicillopepsin-13.4.23.200.446
3bc3OPTCathepsin L13.4.22.150.446
3d8vUD1Bifunctional protein GlmU/0.446
3r8lZ30Cyclin-dependent kinase 22.7.11.220.446
3uyt0CKCasein kinase I isoform delta2.7.11.10.446
3wi6YRZMAP kinase-activated protein kinase 22.7.11.10.446
4anwO92Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.446
4dgmAGICasein kinase II subunit alpha2.7.11.10.446
1dq8COA3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.340.445
1gih1PUCyclin-dependent kinase 22.7.11.220.445
1u3cFADCryptochrome-1/0.445
2acxANPG protein-coupled receptor kinase 62.7.11.160.445
2cmwOLPCasein kinase I isoform gamma-12.7.11.10.445
2fy5SOPCholine O-acetyltransferase2.3.1.60.445
2om9AJAPeroxisome proliferator-activated receptor gamma/0.445
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.445
2wmvZYVSerine/threonine-protein kinase Chk12.7.11.10.445
2x4f16XMyosin light chain kinase family member 42.7.11.10.445
3dndLL2cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
3ezrEZRCyclin-dependent kinase 22.7.11.220.445
3oom507Activin receptor type-12.7.11.300.445
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.445
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.445
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.445
4gk4L90Ephrin type-A receptor 32.7.10.10.445
4ix5ANPUncharacterized protein/0.445
4nxwADPMitochondrial dynamics protein MID51/0.445
4s34ANPMitogen-activated protein kinase 12.7.11.240.445
1ihxSNDGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.444
1pxpCK8Cyclin-dependent kinase 22.7.11.220.444
2bkzSBCCyclin-dependent kinase 22.7.11.220.444
2bujSTUSerine/threonine-protein kinase 16/0.444
2hwrDRDPeroxisome proliferator-activated receptor gamma/0.444
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.444
2pwlACPFibroblast growth factor receptor 2/0.444
2q61SF1Peroxisome proliferator-activated receptor gamma/0.444
2wedPP6Penicillopepsin-13.4.23.200.444
3a7hATPSerine/threonine-protein kinase 242.7.11.10.444
3d7tSTUTyrosine-protein kinase CSK/0.444
3kvxFMYMitogen-activated protein kinase 102.7.11.240.444
3ml9ML9Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
3r8pZ46Cyclin-dependent kinase 22.7.11.220.444
3zm422TDual specificity mitogen-activated protein kinase kinase 12.7.12.20.444
4fkr45KCyclin-dependent kinase 22.7.11.220.444
4i0t1B6Tyrosine-protein kinase SYK2.7.10.20.444
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.444
5adhAPRAlcohol dehydrogenase E chain1.1.1.10.444
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.443
1vjy460TGF-beta receptor type-12.7.11.300.443
1zp9ATPRIO-type serine/threonine-protein kinase Rio12.7.11.10.443
2io6330Wee1-like protein kinase2.7.10.20.443
2itnANPEpidermal growth factor receptor2.7.10.10.443
2j7t274Serine/threonine-protein kinase 102.7.11.10.443
3f63GTXGlutathione transferase GST1-4/0.443
3hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.443
3jpuTY4Transcriptional activator protein LasR/0.443
3r7yZ04Cyclin-dependent kinase 22.7.11.220.443
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.443
4ckiADNProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.443
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.443
4hgt15GCasein kinase I isoform delta2.7.11.10.443
4qmlANPSerine/threonine-protein kinase 242.7.11.10.443
1w0xOLOCyclin-dependent kinase 22.7.11.220.442
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.442
3ctyFADProbable thioredoxin reductase/0.442
3gb2G3BGlycogen synthase kinase-3 beta2.7.11.260.442
3sdi3SDProteasome subunit beta type-53.4.25.10.442
3sdi3SDProteasome subunit beta type-63.4.25.10.442
4b8lA0PAurora kinase B-A2.7.11.10.442
4btmF8ETau-tubulin kinase 12.7.11.10.442
4enhFVXCholesterol 24-hydroxylase/0.442
4o0sADNAurora kinase A2.7.11.10.442
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.441
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.441
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
1lsoNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.441
1oitHDTCyclin-dependent kinase 22.7.11.220.441
1xddAAYIntegrin alpha-L/0.441
2b9iADPMitogen-activated protein kinase FUS32.7.11.240.441
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.441
2r3lSCWCyclin-dependent kinase 22.7.11.220.441
2v7a627Tyrosine-protein kinase ABL12.7.10.20.441
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.441
3bheBZNGag-Pol polyprotein3.4.23.160.441
3c4wATPRhodopsin kinase/0.441
3sw418KCyclin-dependent kinase 22.7.11.220.441
3uli1N3Cyclin-dependent kinase 22.7.11.220.441
4bcnT9NCyclin-dependent kinase 22.7.11.220.441
4caxMYAGlycylpeptide N-tetradecanoyltransferase2.3.1.970.441
4ewhT77Activated CDC42 kinase 1/0.441
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.441
4hyu1BKMitogen-activated protein kinase 82.7.11.240.441
4m69ANPReceptor-interacting serine/threonine-protein kinase 32.7.11.10.441
1ke6LS2Cyclin-dependent kinase 22.7.11.220.440
1pxmCK5Cyclin-dependent kinase 22.7.11.220.440
1pyePM1Cyclin-dependent kinase 22.7.11.220.440
1rekB8LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
1w8cN69Cyclin-dependent kinase 22.7.11.220.440
2cn8DBQSerine/threonine-protein kinase Chk22.7.11.10.440
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.440
2po7CHDFerrochelatase, mitochondrial4.99.1.10.440
2q5g1FAPeroxisome proliferator-activated receptor delta/0.440
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.440
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.440
3w0sANPHygromycin-B 4-O-kinase2.7.1.1630.440
4a9tA9TSerine/threonine-protein kinase Chk22.7.11.10.440
4bgg844Activin receptor type-12.7.11.300.440
4cd0AWJALK tyrosine kinase receptor2.7.10.10.440
4j97ACPFibroblast growth factor receptor 2/0.440
4jq8KJ8Epidermal growth factor receptor2.7.10.10.440
4l3l5FIRibosomal protein S6 kinase beta-12.7.11.10.440
4nr42LKCREB-binding protein/0.440