sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4ajn | 88V | L-lactate dehydrogenase A chain | 1.1.1.27 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4ajn | 88V | L-lactate dehydrogenase A chain | 1.1.1.27 | 1.000 | |
| 4ajj | 88R | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.659 | |
| 4ajo | 88N | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.615 | |
| 4ajp | 88N | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.578 | |
| 2x0i | NAI | Malate dehydrogenase | / | 0.576 | |
| 4rls | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.562 | |
| 3h3f | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.561 | |
| 1hyg | NAP | L-2-hydroxycarboxylate dehydrogenase (NAD(P)(+)) | / | 0.557 | |
| 4okn | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.549 | |
| 1ez4 | NAD | L-lactate dehydrogenase | 1.1.1.27 | 0.545 | |
| 3h3j | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.544 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.543 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.534 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.533 | |
| 4l4s | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.533 | |
| 4ros | APR | Malate dehydrogenase | / | 0.533 | |
| 4mdh | NAD | Malate dehydrogenase, cytoplasmic | 1.1.1.37 | 0.531 | |
| 4i8x | 6P3 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.524 | |
| 4nd2 | A3D | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.524 | |
| 5a1t | NAI | L-lactate dehydrogenase | / | 0.520 | |
| 1pzf | A3D | Lactate dehydrogenase | / | 0.519 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.519 | |
| 1sow | NAD | L-lactate dehydrogenase | 1.1.1.27 | 0.518 | |
| 1pzh | NAD | Lactate dehydrogenase | / | 0.517 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.513 | |
| 3gvh | NAD | Malate dehydrogenase | / | 0.511 | |
| 3wsw | NAD | L-lactate dehydrogenase | / | 0.511 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.510 | |
| 2a92 | NAI | L-lactate dehydrogenase | / | 0.508 | |
| 1yon | A2R | 2-dehydropantoate 2-reductase | 1.1.1.169 | 0.507 | |
| 4nd4 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.507 | |
| 4jnk | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.506 | |
| 1ie3 | NAD | Malate dehydrogenase | / | 0.504 | |
| 1dxy | NAD | D-2-hydroxyisocaproate dehydrogenase | 1.1.1 | 0.501 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.501 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.500 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.499 | |
| 1ur5 | NAD | Malate dehydrogenase | / | 0.496 | |
| 2d8a | NAD | L-threonine 3-dehydrogenase | / | 0.496 | |
| 1ib6 | NAD | Malate dehydrogenase | / | 0.495 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.495 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.494 | |
| 2fn7 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.494 | |
| 4e2d | FMN | Dehydrogenase | / | 0.493 | |
| 5a3b | APR | SIR2 family protein | / | 0.493 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.492 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.491 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.491 | |
| 2aa3 | AP0 | L-lactate dehydrogenase | / | 0.490 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.490 | |
| 2hjr | APR | Malate dehydrogenase, adjacent gene encodes predicted lactate dehydrogenase | / | 0.489 | |
| 2x0r | NAD | Malate dehydrogenase | / | 0.489 | |
| 3wfj | NAD | 2-dehydropantoate 2-reductase | / | 0.489 | |
| 4jic | FMN | GTN Reductase | / | 0.489 | |
| 1uxj | NAD | Malate dehydrogenase | / | 0.488 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.488 | |
| 4die | C5P | Cytidylate kinase | / | 0.488 | |
| 1fxs | NAP | GDP-L-fucose synthase | / | 0.487 | |
| 1b8v | NAD | Malate dehydrogenase | / | 0.486 | |
| 1emd | NAD | Malate dehydrogenase | / | 0.486 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.486 | |
| 4e2b | FMN | Dehydrogenase | / | 0.486 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.485 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.484 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.482 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.482 | |
| 1uxk | NAD | Malate dehydrogenase | / | 0.481 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.481 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.481 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.481 | |
| 4j7x | NAP | Sepiapterin reductase | 1.1.1.153 | 0.481 | |
| 1r2j | FAD | FkbI | / | 0.480 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.480 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.480 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.479 | |
| 1v9a | SAH | Uncharacterized protein | / | 0.479 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.479 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.479 | |
| 3bv2 | P38 | Mitogen-activated protein kinase 14 | / | 0.479 | |
| 3pqf | NAD | L-lactate dehydrogenase | 1.1.1.27 | 0.478 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.478 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.478 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.477 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.476 | |
| 2cmj | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.476 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.476 | |
| 4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.475 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.475 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.475 | |
| 1hf3 | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.474 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.474 | |
| 3nd1 | SAH | Precorrin-6A synthase (Deacetylating) | / | 0.474 | |
| 4dh6 | 0KN | Beta-secretase 1 | 3.4.23.46 | 0.474 | |
| 4i6a | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.474 | |
| 4l4x | NDP | AmphI | / | 0.474 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.473 | |
| 1guy | NAD | Malate dehydrogenase | / | 0.473 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.473 | |
| 4j7u | NAP | Sepiapterin reductase | 1.1.1.153 | 0.473 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.473 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.472 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.472 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.472 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.471 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.471 | |
| 2hsd | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.471 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.471 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.471 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.471 | |
| 4nu5 | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.471 | |
| 1i3l | NAD | UDP-glucose 4-epimerase | / | 0.470 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.470 | |
| 2wot | ZZG | TGF-beta receptor type-1 | 2.7.11.30 | 0.470 | |
| 4dlb | NAD | S-(hydroxymethyl)glutathione dehydrogenase | / | 0.470 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.469 | |
| 1k6v | XN2 | Gag-Pol polyprotein | 3.4.23.16 | 0.469 | |
| 2g5c | NAD | Prephenate dehydrogenase | / | 0.469 | |
| 2r2n | KYN | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.469 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.469 | |
| 3rud | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.469 | |
| 4dja | FAD | (6-4) photolyase | / | 0.469 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.469 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.469 | |
| 1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.468 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.468 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.468 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.468 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.468 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.468 | |
| 1di8 | DTQ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.467 | |
| 1gv0 | NAD | Malate dehydrogenase | / | 0.467 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.467 | |
| 3a4o | STU | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.467 | |
| 3hwr | NDP | 2-dehydropantoate 2-reductase | / | 0.467 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.467 | |
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 0.467 | |
| 2ome | NAD | C-terminal-binding protein 2 | / | 0.466 | |
| 2tps | TPS | Thiamine-phosphate synthase | / | 0.466 | |
| 4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.466 | |
| 4nxw | ADP | Mitochondrial dynamics protein MID51 | / | 0.466 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.466 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.466 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.465 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.465 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.465 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.465 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.465 | |
| 3e8x | NAP | BH1520 protein | / | 0.465 | |
| 3sj7 | NDP | 3-oxoacyl-(Acyl-carrier-protein) reductase, putative | / | 0.465 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.465 | |
| 4fj1 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.465 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.465 | |
| 1b8u | NAD | Malate dehydrogenase | / | 0.464 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.464 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 2dc1 | NAD | Probable L-aspartate dehydrogenase | / | 0.464 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.464 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.464 | |
| 3oet | NAD | Erythronate-4-phosphate dehydrogenase | / | 0.464 | |
| 4gl4 | NAI | Alcohol dehydrogenase class-3 | / | 0.464 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.464 | |
| 4u9a | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.464 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.464 | |
| 1p0h | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.463 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.463 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 3ad9 | NAD | Subunit alpha of sarocosine oxidase | / | 0.463 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 3e39 | FMN | Nitroreductase | / | 0.463 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.463 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.463 | |
| 4kwh | NAP | Reductase homolog | / | 0.463 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.463 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.463 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.463 | |
| 1qrr | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.462 | |
| 2uzf | CAA | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.462 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.462 | |
| 4dt9 | GMP | APH(2'')-Id | / | 0.462 | |
| 4hxy | NDP | Plm1 | / | 0.462 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.462 | |
| 1rw8 | 580 | TGF-beta receptor type-1 | 2.7.11.30 | 0.461 | |
| 2ldb | NAD | L-lactate dehydrogenase | 1.1.1.27 | 0.461 | |
| 2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.461 | |
| 2q61 | SF1 | Peroxisome proliferator-activated receptor gamma | / | 0.461 | |
| 2vna | NAP | Prostaglandin reductase 2 | 1.3.1.48 | 0.461 | |
| 3tri | NAP | Pyrroline-5-carboxylate reductase | / | 0.461 | |
| 4b8z | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.461 | |
| 4jb1 | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.461 | |
| 1f5f | DHT | Sex hormone-binding globulin | / | 0.460 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.460 | |
| 1kr2 | TAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.460 | |
| 1wze | NAD | Malate dehydrogenase | / | 0.460 | |
| 1xel | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.460 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.460 | |
| 3r6s | CMP | CRP-like cAMP-activated global transcriptional regulator | / | 0.460 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.460 | |
| 4b8w | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.460 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.460 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.459 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.459 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.459 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.459 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.459 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.459 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.459 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.459 | |
| 3c1y | 2BA | DNA integrity scanning protein DisA | / | 0.459 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.459 | |
| 3pgq | GY3 | Acetyl-CoA carboxylase | / | 0.459 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.459 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.459 | |
| 5a3c | NAD | SIR2 family protein | / | 0.459 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.458 | |
| 1g0n | NDP | Tetrahydroxynaphthalene reductase | 1.1.1.252 | 0.458 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.458 | |
| 1gqt | ACP | Ribokinase | / | 0.458 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.458 | |
| 1qo8 | FAD | Fumarate reductase flavoprotein subunit | / | 0.458 | |
| 1yba | NAD | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.458 | |
| 2v13 | C40 | Renin | 3.4.23.15 | 0.458 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.458 | |
| 4mxx | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.458 | |
| 4rf2 | NAP | NADPH dependent R-specific alcohol dehydrogenase | / | 0.458 | |
| 4v12 | POG | MaoC like domain protein | / | 0.458 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.457 | |
| 1rby | KEU | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.457 | |
| 1u8f | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.457 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.457 | |
| 2cgp | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.457 | |
| 2p6l | SAH | Diphthine synthase | / | 0.457 | |
| 3pef | NAP | Glyoxalate/3-oxopropanoate/4-oxobutanoate reductase | / | 0.457 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.457 | |
| 3up0 | D7S | aceDAF-12 | / | 0.457 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.457 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.457 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.457 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.456 | |
| 1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 1npt | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.456 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.456 | |
| 2aa0 | MTP | Adenosine kinase | 2.7.1.20 | 0.456 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.456 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.456 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.456 | |
| 3f1k | NAP | Uncharacterized oxidoreductase YciK | 1 | 0.456 | |
| 3kb6 | NAD | D-lactate dehydrogenase | / | 0.456 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.456 | |
| 3tqh | NDP | Quinone oxidoreductase | / | 0.456 | |
| 4h8a | NAI | Ureidoglycolate dehydrogenase (NAD(+)) | 1.1.1.350 | 0.456 | |
| 4kxn | 6K6 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | / | 0.456 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.456 | |
| 1bmd | NAD | Malate dehydrogenase | / | 0.455 | |
| 1c1d | NAI | Phenylalanine dehydrogenase | / | 0.455 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 1pjc | NAD | Alanine dehydrogenase | / | 0.455 | |
| 1u4o | NDD | L-lactate dehydrogenase | 1.1.1.27 | 0.455 | |
| 1udy | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.455 | |
| 1wn3 | HXC | Phenylacetic acid degradation protein PaaI | / | 0.455 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.455 | |
| 2fzw | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.455 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.455 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 3iw1 | ASD | Steroid C26-monooxygenase | 1.14.13.141 | 0.455 | |
| 3pm9 | FAD | Putative oxidoreductase | / | 0.455 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.455 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.455 | |
| 4l8u | 9AZ | Serum albumin | / | 0.455 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.454 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.454 | |
| 1fy7 | COA | Histone acetyltransferase ESA1 | / | 0.454 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.454 | |
| 1vl8 | NAP | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.454 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.454 | |
| 1xkv | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.454 | |
| 2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 0.454 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.454 | |
| 2owg | SAH | Diphthine synthase | / | 0.454 | |
| 2ozu | ACO | Histone acetyltransferase KAT6A | / | 0.454 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.454 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.454 | |
| 4jvf | 17X | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.454 | |
| 4u7w | NDP | MxaA | / | 0.454 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.453 | |
| 1knr | FAD | L-aspartate oxidase | 1.4.3.16 | 0.453 | |
| 1tdr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1z7y | AA5 | Cysteine synthase 1 | 2.5.1.47 | 0.453 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.453 | |
| 2jah | NDP | Clavaldehyde dehydrogenase | / | 0.453 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.453 | |
| 2wsb | NAD | Galactitol dehydrogenase | / | 0.453 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.453 | |
| 3jqp | A2P | Ferredoxin--NADP reductase, apicoplast | / | 0.453 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.453 | |
| 5af7 | FAD | Acyl-CoA dehydrogenase | / | 0.453 | |
| 1a9z | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.452 | |
| 1lde | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.452 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.452 | |
| 1oaa | NAP | Sepiapterin reductase | 1.1.1.153 | 0.452 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.452 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 2bun | FAD | AppA protein | / | 0.452 | |
| 2nmt | NHM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.452 | |
| 2p5c | SAH | Diphthine synthase | / | 0.452 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.452 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.452 | |
| 2xh9 | J01 | Uncharacterized protein | / | 0.452 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.452 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.452 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.452 | |
| 4uun | NAI | L-lactate dehydrogenase | / | 0.452 | |
| 5dmh | ADP | 3-oxo-tetronate kinase | / | 0.452 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.451 | |
| 1y57 | MPZ | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.451 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.451 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.451 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.451 | |
| 3ak4 | NAD | NADH-dependent quinuclidinone reductase | / | 0.451 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.451 | |
| 3il1 | B5D | Glutamate receptor 2 | / | 0.451 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.451 | |
| 3u4c | NDP | NADPH-dependent reductase BacG | / | 0.451 | |
| 4u2s | FDA | Cholesterol oxidase | 1.1.3.6 | 0.451 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.450 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.450 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.450 | |
| 1nhh | ANP | DNA mismatch repair protein MutL | / | 0.450 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.450 | |
| 2huv | SAH | Diphthine synthase | / | 0.450 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.450 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.450 | |
| 2pg0 | FAD | Acyl-CoA dehydrogenase | / | 0.450 | |
| 2zb3 | NDP | Prostaglandin reductase 2 | 1.3.1.48 | 0.450 | |
| 3nga | 3NG | Casein kinase II subunit alpha | 2.7.11.1 | 0.450 | |
| 3oqu | A8S | Abscisic acid receptor PYL9 | / | 0.450 | |
| 3sf6 | FDA | Glutaryl-CoA dehydrogenase | / | 0.450 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.450 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.450 | |
| 5c8w | PCG | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.450 | |
| 5cdt | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.450 | |
| 1dbv | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.449 | |
| 1e3w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.449 | |
| 1h74 | ADP | Homoserine kinase | 2.7.1.39 | 0.449 | |
| 1hyh | NAD | L-2-hydroxyisocaproate dehydrogenase | / | 0.449 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 1okk | GCP | Signal recognition particle protein | / | 0.449 | |
| 1okk | GCP | Signal recognition particle receptor FtsY | / | 0.449 | |
| 1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.449 | |
| 2ev9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.449 | |
| 2qbn | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.449 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.449 | |
| 3otf | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | / | 0.449 | |
| 3uqd | ATP | ATP-dependent 6-phosphofructokinase isozyme 2 | 2.7.1.11 | 0.449 | |
| 4dgo | 0JW | Casein kinase II subunit alpha | 2.7.11.1 | 0.449 | |
| 4dpw | AGS | Mevalonate diphosphate decarboxylase | / | 0.449 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.449 | |
| 4kin | 1M8 | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 4lxh | C1E | Alpha/beta hydrolase fold | / | 0.449 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.449 | |
| 4y0k | NAP | AntE | / | 0.449 | |
| 1cjk | FOK | Adenylate cyclase type 2 | / | 0.448 | |
| 1cjk | FOK | Adenylate cyclase type 5 | / | 0.448 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.448 | |
| 2fvl | NAP | Aldo-keto reductase family 1 member C4 | 1.1.1.225 | 0.448 | |
| 2iw8 | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 2ooy | ATP | 5'-AMP-activated protein kinase subunit gamma | / | 0.448 | |
| 2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 2zva | 1N1 | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.448 | |
| 3cd3 | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.448 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.448 | |
| 3flw | FLW | Mitogen-activated protein kinase 14 | / | 0.448 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 3s55 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.448 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.448 | |
| 3t11 | 3T1 | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 3v1y | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1, cytosolic | 1.2.1.12 | 0.448 | |
| 3vsp | EK8 | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 3wyc | NAP | Meso-diaminopimelate D-dehydrogenase | 1.4.1.16 | 0.448 | |
| 4gj3 | 0XP | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.448 | |
| 4kzo | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.448 | |
| 4lcj | NAD | C-terminal-binding protein 2 | / | 0.448 | |
| 5dt9 | NAD | Erythronate-4-phosphate dehydrogenase | / | 0.448 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.447 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.447 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 1osv | CHC | Bile acid receptor | / | 0.447 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.447 | |
| 2ign | FAD | Pyranose 2-oxidase | / | 0.447 | |
| 2p8u | COA | Hydroxymethylglutaryl-CoA synthase, cytoplasmic | 2.3.3.10 | 0.447 | |
| 2xgs | 44P | Uncharacterized protein | / | 0.447 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.447 | |
| 2zno | S44 | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 3d8b | ADP | Fidgetin-like protein 1 | 3.6.4 | 0.447 | |
| 3doc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.447 | |
| 3ey9 | TDP | Pyruvate dehydrogenase [ubiquinone] | 1.2.5.1 | 0.447 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.447 | |
| 3lsi | FAD | Pyranose 2-oxidase | / | 0.447 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.447 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.447 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.447 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.447 | |
| 4a6n | FAD | TetX family tetracycline inactivation enzyme | / | 0.447 | |
| 4aa5 | NQB | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 4fse | 0VA | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4gk4 | L90 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.447 | |
| 4l4f | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 1a7k | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.446 | |
| 1lso | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.446 | |
| 1mp0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.446 | |
| 1nlm | UD1 | UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase | / | 0.446 | |
| 1o8c | NDP | Probable acrylyl-CoA reductase AcuI | 1.3.1.84 | 0.446 | |
| 1y9d | TPP | Pyruvate oxidase | 1.2.3.3 | 0.446 | |
| 2dr3 | ADP | UPF0273 protein PH0284 | / | 0.446 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.446 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.446 | |
| 2p2x | SAH | Diphthine synthase | / | 0.446 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.446 | |
| 2vzz | SCA | Putative succinyl-CoA transferase Rv0802c | 2.8.3 | 0.446 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.446 | |
| 2zjm | F1M | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 3m6i | NAD | L-arabinitol 4-dehydrogenase | 1.1.1.12 | 0.446 | |
| 3mvm | 39P | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 3o0q | ADN | Vitamin B12-dependent ribonucleotide reductase | / | 0.446 | |
| 3o26 | NDP | Salutaridine reductase | / | 0.446 | |
| 3r7k | FDA | Probable acyl CoA dehydrogenase | / | 0.446 | |
| 3ruc | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.446 | |
| 3uce | NDP | Dehydrogenase | / | 0.446 | |
| 3upf | 0BU | Polyprotein | / | 0.446 | |
| 3vw6 | IM6 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.446 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.446 | |
| 3zuy | TCH | Transporter | / | 0.446 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.446 | |
| 4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 4fuy | EK2 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.446 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.446 | |
| 4ocp | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.446 | |
| 4qe6 | JN3 | Bile acid receptor | / | 0.446 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.446 | |
| 1b15 | NAE | Alcohol dehydrogenase | 1.1.1.1 | 0.445 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 1i9c | 5AD | Glutamate mutase epsilon subunit | / | 0.445 | |
| 1o6k | ANP | RAC-beta serine/threonine-protein kinase | 2.7.11.1 | 0.445 | |
| 1txz | APR | Probable ADP-ribose 1''-phosphate phosphatase YML087W | 3.1.3.84 | 0.445 | |
| 1wwk | NAD | 307aa long hypothetical phosphoglycerate dehydrogenase | / | 0.445 | |
| 2fy4 | COA | Choline O-acetyltransferase | 2.3.1.6 | 0.445 | |
| 2h94 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.445 | |
| 2itn | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.445 | |
| 2rg5 | 279 | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 2wdz | NAD | Galactitol dehydrogenase | / | 0.445 | |
| 3a3g | DLZ | Lumazine protein | / | 0.445 | |
| 3at3 | ATK | Casein kinase II subunit alpha | 2.7.11.1 | 0.445 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.445 | |
| 3ggp | NAD | Prephenate dehydrogenase | / | 0.445 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.445 | |
| 3ijr | NAD | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.445 | |
| 3mjh | GTP | Ras-related protein Rab-5A | / | 0.445 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.445 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.445 | |
| 3owj | 1EL | Casein kinase II subunit alpha | 2.7.11.1 | 0.445 | |
| 3p19 | NDP | Putative blue fluorescent protein | / | 0.445 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.445 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.445 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.445 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.445 | |
| 4nwz | FAD | FAD-dependent pyridine nucleotide-disulfide oxidoreductase | / | 0.445 | |
| 4ocv | ANP | Aminoglycoside phosphotransferase | / | 0.445 | |
| 4yxm | 2BA | DNA integrity scanning protein DisA | / | 0.445 | |
| 4zoh | FAD | Putative oxidoreductase FAD-binding subunit | / | 0.445 | |
| 5a88 | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.445 | |
| 5ify | UMP | Glucose-1-phosphate thymidylyltransferase | / | 0.445 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.445 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.444 | |
| 1o0s | NAI | NAD-dependent malic enzyme, mitochondrial | 1.1.1.38 | 0.444 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 2eba | FAD | Putative glutaryl-CoA dehydrogenase | / | 0.444 | |
| 2el0 | SAH | Diphthine synthase | / | 0.444 | |
| 2qoq | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.444 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.444 | |
| 2w2l | NAD | D-mandelate dehydrogenase | / | 0.444 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2xw7 | NDP | Dihydrofolate reductase | / | 0.444 | |
| 2ylz | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.444 | |
| 3a1c | ACP | Probable copper-exporting P-type ATPase A | 3.6.3.54 | 0.444 | |
| 3clb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.444 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3gkj | HC3 | Niemann-Pick C1 protein | / | 0.444 | |
| 3gy0 | NAP | NAD(P)-dependent oxidoreductase | / | 0.444 | |
| 3oq6 | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.444 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.444 | |
| 3sx2 | NAD | Uncharacterized protein | / | 0.444 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.444 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.444 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 4hy6 | FJ1 | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 4iqg | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.444 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 4wou | GDP | Phosphoenolpyruvate carboxykinase [GTP] | / | 0.444 | |
| 4yb7 | ATP | ATP phosphoribosyltransferase | / | 0.444 | |
| 5jyd | NAD | Short chain dehydrogenase | / | 0.444 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.444 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.443 | |
| 1cs4 | FOK | Adenylate cyclase type 2 | / | 0.443 | |
| 1cs4 | FOK | Adenylate cyclase type 5 | / | 0.443 | |
| 1i2c | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.443 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1kvk | ATP | Mevalonate kinase | 2.7.1.36 | 0.443 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.443 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.443 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.443 | |
| 1rm5 | NDP | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.443 | |
| 1ybm | NAP | Uncharacterized protein At5g02240 | / | 0.443 | |
| 2cwf | NDP | Delta(1)-pyrroline-2-carboxylate/Delta(1)-piperideine-2-carboxylate reductase | / | 0.443 | |
| 2dxv | SAH | Diphthine synthase | / | 0.443 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.443 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.443 | |
| 2itv | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.443 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.443 | |
| 2qnq | QN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 2rgh | FAD | Alpha-Glycerophosphate Oxidase | / | 0.443 | |
| 2xw1 | 9NV | Serum albumin | / | 0.443 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2ylw | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.443 | |
| 3fsk | RO6 | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 3h3c | P1E | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.443 | |
| 3nbv | ANP | Ketohexokinase | / | 0.443 | |
| 3nl6 | TPS | Uncharacterized protein | / | 0.443 | |
| 3o15 | 3NM | Thiamine-phosphate synthase | / | 0.443 | |
| 3rn8 | RN8 | Glutamate receptor 2 | / | 0.443 | |
| 3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.443 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.443 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.443 | |
| 4ceq | QCH | Integrase | / | 0.443 | |
| 4dd8 | BAT | Disintegrin and metalloproteinase domain-containing protein 8 | 3.4.24 | 0.443 | |
| 4h4y | NAP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.443 | |
| 4idg | NAD | Putative UDP-glucose 4-epimerase | / | 0.443 | |
| 4jia | 1K3 | Tyrosine-protein kinase JAK2 | / | 0.443 | |
| 4loq | SB4 | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 4lt6 | 3AT | Poly(A) polymerase gamma | 2.7.7.19 | 0.443 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.443 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.443 | |
| 6adh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.443 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.442 | |
| 1c70 | L75 | Protease | / | 0.442 | |
| 1dhj | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1fwk | ADP | Homoserine kinase | 2.7.1.39 | 0.442 | |
| 1h2b | NAJ | NAD-dependent alcohol dehydrogenase | / | 0.442 | |
| 1kev | NDP | NADP-dependent isopropanol dehydrogenase | 1.1.1.80 | 0.442 | |
| 1men | GAR | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.442 | |
| 1nq5 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.442 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 2e1m | FAD | L-glutamate oxidase | / | 0.442 | |
| 2emu | SAH | Diphthine synthase | / | 0.442 | |
| 2eni | SAH | Diphthine synthase | / | 0.442 | |
| 2gsd | NAD | Formate dehydrogenase | / | 0.442 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 2itu | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.442 | |
| 2j3i | NAP | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.442 | |
| 2q7v | FAD | Thioredoxin reductase | / | 0.442 | |
| 2xpu | TDC | Tetracycline repressor protein class D | / | 0.442 | |
| 2ym2 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.442 | |
| 3aut | NAI | Glucose 1-dehydrogenase 4 | 1.1.1.47 | 0.442 | |
| 3bbr | BHY | Glutamate receptor 2 | / | 0.442 | |
| 3cif | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.442 | |
| 3daf | FEG | 5,10-methenyltetrahydromethanopterin hydrogenase | 1.12.98.2 | 0.442 | |
| 3mpt | 1GK | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 3r5y | F42 | Uncharacterized protein | / | 0.442 | |
| 3sig | AR6 | Uncharacterized protein | / | 0.442 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.442 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.442 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.442 | |
| 4e5k | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.442 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.442 | |
| 4fgr | ADP | Phosphoribosylaminoimidazole-succinocarboxamide synthase | 6.3.2.6 | 0.442 | |
| 4fj2 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.442 | |
| 4gi2 | NAP | Crotonyl-CoA carboxylase/reductase | / | 0.442 | |
| 4ki8 | ADP | 60 kDa chaperonin | / | 0.442 | |
| 4o0l | NDP | NADPH-dependent 3-quinuclidinone reductase | / | 0.442 | |
| 4pan | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.442 | |
| 4qxp | 1YE | Stimulator of interferon genes protein | / | 0.442 | |
| 4rpg | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.442 | |
| 4rrv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.442 | |
| 4xx9 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.442 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.442 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 5jsc | FAD | Putative acyl-CoA dehydrogenase | / | 0.442 | |
| 1drb | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1e7q | NAP | GDP-L-fucose synthase | / | 0.441 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.441 | |
| 1kf6 | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.441 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1nvq | UCN | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 1qpj | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.441 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.441 | |
| 1sny | NAP | LD36273p | / | 0.441 | |
| 1uyh | PU0 | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 2dv7 | SAH | Diphthine synthase | / | 0.441 | |
| 2pbw | DOQ | Glutamate receptor ionotropic, kainate 1 | / | 0.441 | |
| 2pch | SAH | Diphthine synthase | / | 0.441 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.441 | |
| 2v9j | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.441 | |
| 2ww4 | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.441 | |
| 2yyi | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.441 | |
| 3dme | FAD | Putative conserved exported protein | / | 0.441 | |
| 3hu1 | AGS | Transitional endoplasmic reticulum ATPase | 3.6.4.6 | 0.441 | |
| 3ids | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.441 | |
| 3ijo | B4D | Glutamate receptor 2 | / | 0.441 | |
| 3pll | F06 | Endothiapepsin | 3.4.23.22 | 0.441 | |
| 3tdv | GDP | Gentamicin resistance protein | / | 0.441 | |
| 3tsc | NAD | Uncharacterized protein | / | 0.441 | |
| 3uwq | U5P | Orotidine 5'-phosphate decarboxylase | / | 0.441 | |
| 3wds | NAD | NADH-dependent quinuclidinone reductase | / | 0.441 | |
| 4a06 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.441 | |
| 4dxh | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.441 | |
| 4e73 | 0NR | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.441 | |
| 4ei7 | GDP | Plasmid replication protein RepX | / | 0.441 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 4rqu | NAD | Alcohol dehydrogenase class-P | / | 0.441 | |
| 4xq9 | NAD | Homospermidine synthase | 2.5.1.44 | 0.441 | |
| 5dg3 | U21 | Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase | / | 0.441 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.440 | |
| 1t9g | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.440 | |
| 2bd0 | NAP | Sepiapterin reductase | / | 0.440 | |
| 2i4z | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 2jcv | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.440 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 2r9e | SDX | Citrate synthase | 2.3.3.16 | 0.440 | |
| 2y3s | TIR | TamL | / | 0.440 | |
| 2ydx | NAP | Methionine adenosyltransferase 2 subunit beta | / | 0.440 | |
| 3ac1 | KZI | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.440 | |
| 3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.440 | |
| 3f3s | NAD | Lambda-crystallin homolog | / | 0.440 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.440 | |
| 3lu1 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.440 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3r83 | Z14 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.440 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.440 | |
| 4d04 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.440 | |
| 4dl9 | NAD | S-(hydroxymethyl)glutathione dehydrogenase | / | 0.440 | |
| 4dpu | AGS | Mevalonate diphosphate decarboxylase | / | 0.440 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.440 | |
| 4xgx | ADP | FAD:protein FMN transferase | / | 0.440 | |
| 4ysw | FAD | Xanthine dehydrogenase/oxidase | / | 0.440 |