sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3kmc | 403 | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3kmc | 403 | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 1.000 | |
| 3le9 | 727 | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.634 | |
| 2i47 | KGY | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.627 | |
| 1zxc | IH6 | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.618 | |
| 3lgp | 50X | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.613 | |
| 3b92 | 440 | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.596 | |
| 2i47 | INN | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.592 | |
| 3l0v | 724 | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.590 | |
| 3kme | INN | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.580 | |
| 2a8h | 4NH | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.570 | |
| 3hy7 | 097 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.550 | |
| 1bzs | BSI | Neutrophil collagenase | 3.4.24.34 | 0.543 | |
| 3e8r | 615 | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.533 | |
| 3l0t | INN | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.532 | |
| 1biw | S80 | Stromelysin-1 | 3.4.24.17 | 0.529 | |
| 2woa | 023 | Macrophage metalloelastase | 3.4.24.65 | 0.525 | |
| 3b8z | 294 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.522 | |
| 1atl | 0QI | Snake venom metalloproteinase atrolysin-D | 3.4.24.42 | 0.521 | |
| 1g05 | BBH | Stromelysin-1 | 3.4.24.17 | 0.521 | |
| 3hy9 | 098 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.515 | |
| 3kds | NHX | ATP-dependent zinc metalloprotease FtsH | / | 0.513 | |
| 1caq | DPS | Stromelysin-1 | 3.4.24.17 | 0.510 | |
| 3hyg | 099 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.508 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.507 | |
| 3ljt | LA3 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.507 | |
| 1hy7 | MBS | Stromelysin-1 | 3.4.24.17 | 0.505 | |
| 1g4k | HQQ | Stromelysin-1 | 3.4.24.17 | 0.504 | |
| 1zvx | FIN | Neutrophil collagenase | 3.4.24.34 | 0.503 | |
| 3iod | A6D | Pantothenate synthetase | 6.3.2.1 | 0.502 | |
| 2wo9 | 023 | Macrophage metalloelastase | 3.4.24.65 | 0.501 | |
| 2oxw | ILE_ALA_GLY | Macrophage metalloelastase | 3.4.24.65 | 0.500 | |
| 2wo8 | 077 | Macrophage metalloelastase | 3.4.24.65 | 0.500 | |
| 3ljg | EEF | Macrophage metalloelastase | 3.4.24.65 | 0.500 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.495 | |
| 1mnc | PLH | Neutrophil collagenase | 3.4.24.34 | 0.494 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.493 | |
| 4cgg | K5Q | Integrase | / | 0.493 | |
| 1bw9 | NAD | Phenylalanine dehydrogenase | / | 0.492 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.492 | |
| 4g9l | NGH | Stromelysin-1 | 3.4.24.17 | 0.492 | |
| 4ja1 | NGH | Stromelysin-1 | 3.4.24.17 | 0.492 | |
| 1g49 | 111 | Stromelysin-1 | 3.4.24.17 | 0.491 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.491 | |
| 2w0d | CGS | Macrophage metalloelastase | 3.4.24.65 | 0.491 | |
| 3c8b | ARG_ARG_GLY_ILE_NH2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.491 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.491 | |
| 3lqs | PSZ | D-alanine aminotransferase | 2.6.1.21 | 0.490 | |
| 2wo8 | 023 | Macrophage metalloelastase | 3.4.24.65 | 0.489 | |
| 4dpe | NGH | Stromelysin-1 | 3.4.24.17 | 0.489 | |
| 1utt | CP8 | Macrophage metalloelastase | 3.4.24.65 | 0.488 | |
| 1gkc | NFH | Matrix metalloproteinase-9 | 3.4.24.35 | 0.487 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.487 | |
| 3oho | Z79 | Stromelysin-1 | 3.4.24.17 | 0.487 | |
| 4gr8 | R4C | Macrophage metalloelastase | 3.4.24.65 | 0.487 | |
| 3aig | 0ZC | Snake venom metalloproteinase adamalysin-2 | 3.4.24.46 | 0.486 | |
| 3t4n | ADP | 5'-AMP-activated protein kinase subunit gamma | / | 0.486 | |
| 1d7x | SPC | Stromelysin-1 | 3.4.24.17 | 0.485 | |
| 2get | COK | Pantothenate kinase | 2.7.1.33 | 0.485 | |
| 1b8y | IN7 | Stromelysin-1 | 3.4.24.17 | 0.484 | |
| 1j1z | ATP | Argininosuccinate synthase | / | 0.484 | |
| 1hv5 | RXP | Stromelysin-3 | 3.4.24 | 0.483 | |
| 1rm8 | BAT | Matrix metalloproteinase-16 | 3.4.24 | 0.483 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.483 | |
| 2dw0 | GM6 | Zinc metalloproteinase-disintegrin-like VAP2B | 3.4.24 | 0.483 | |
| 2ow1 | 7MR | Matrix metalloproteinase-9 | 3.4.24.35 | 0.483 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.483 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.482 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.481 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.481 | |
| 1zs0 | EIN | Neutrophil collagenase | 3.4.24.34 | 0.480 | |
| 4wdg | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.480 | |
| 3tsk | QEG | Macrophage metalloelastase | 3.4.24.65 | 0.479 | |
| 6tmn | 0PI | Thermolysin | 3.4.24.27 | 0.479 | |
| 4loc | BTN | Pyruvate carboxylase | / | 0.478 | |
| 5fm7 | ADP | RuvB-like helicase | / | 0.478 | |
| 2jsd | NGH | Matrix metalloproteinase-20 | 3.4.24 | 0.477 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.477 | |
| 4dym | IYZ | Activin receptor type-1 | 2.7.11.30 | 0.477 | |
| 1j39 | UPG | DNA beta-glucosyltransferase | / | 0.476 | |
| 1w0k | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.476 | |
| 1w0k | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.476 | |
| 2j83 | BAT | Ulilysin | 3.4.24 | 0.476 | |
| 2jih | 097 | A disintegrin and metalloproteinase with thrombospondin motifs 1 | 3.4.24 | 0.476 | |
| 2jt2 | C90 | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.475 | |
| 3i7g | 732 | Collagenase 3 | 3.4.24 | 0.475 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.475 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.475 | |
| 4la1 | FAD | Thioredoxin glutathione reductase | / | 0.475 | |
| 2x8h | FAD | Thioredoxin glutathione reductase | / | 0.474 | |
| 3ik6 | HCZ | Glutamate receptor 2 | / | 0.474 | |
| 4ceq | QCH | Integrase | / | 0.474 | |
| 4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.474 | |
| 2jkv | NAP | 6-phosphogluconate dehydrogenase, decarboxylating | 1.1.1.44 | 0.473 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.473 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.473 | |
| 4gb9 | 0WR | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.473 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.472 | |
| 4oh4 | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.472 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.472 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.471 | |
| 1bqo | N25 | Stromelysin-1 | 3.4.24.17 | 0.470 | |
| 1e8z | STU | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.470 | |
| 4fry | NAD | Putative signal-transduction protein with CBS domains | / | 0.470 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.469 | |
| 2b4t | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.469 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.469 | |
| 3zxh | E41 | Collagenase 3 | 3.4.24 | 0.469 | |
| 4avl | TMP | Polymerase acidic protein | / | 0.469 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.469 | |
| 4k28 | NAD | Shikimate dehydrogenase family protein | / | 0.469 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.469 | |
| 5dp2 | NAP | CurF | / | 0.469 | |
| 5kj1 | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.469 | |
| 2ovz | 5MR | Matrix metalloproteinase-9 | 3.4.24.35 | 0.468 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.468 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.468 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.468 | |
| 3v0o | 4GW | Histo-blood group ABO system transferase | / | 0.468 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.468 | |
| 4aux | XTC | Tetracycline repressor protein class D | / | 0.468 | |
| 4ke0 | 1R8 | Beta-secretase 1 | 3.4.23.46 | 0.468 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 2ix5 | FAD | Acyl-coenzyme A oxidase 4, peroxisomal | 1.3.3.6 | 0.467 | |
| 4xfj | ANP | Argininosuccinate synthase | / | 0.467 | |
| 5ej6 | TD6 | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.467 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.466 | |
| 1zrq | FAD | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.466 | |
| 2xs3 | ALA_PHE_THR_SER | Karilysin | 3.4.24 | 0.466 | |
| 2zcv | NDP | Quinone oxidoreductase 2 | 1.6.5.2 | 0.466 | |
| 4qai | FMN | NADPH dehydrogenase | / | 0.466 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.465 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.465 | |
| 1pag | FMP | Antiviral protein I | 3.2.2.22 | 0.465 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.465 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.465 | |
| 4i03 | L88 | Macrophage metalloelastase | 3.4.24.65 | 0.465 | |
| 4wcx | SAM | Biotin and thiamin synthesis associated | / | 0.465 | |
| 5ahs | FAD | Acyl-CoA dehydrogenase | / | 0.465 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.464 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.464 | |
| 2gcg | NDP | Glyoxylate reductase/hydroxypyruvate reductase | 1.1.1.79 | 0.464 | |
| 2ign | FAD | Pyranose 2-oxidase | / | 0.464 | |
| 2jnp | NGH | Stromelysin-1 | 3.4.24.17 | 0.464 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.464 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.464 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.463 | |
| 1q3a | NGH | Stromelysin-2 | 3.4.24.22 | 0.463 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.463 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.463 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.463 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.463 | |
| 2f3r | G5P | Guanylate kinase | 2.7.4.8 | 0.463 | |
| 2fre | FMN | NAD(P)H-flavin oxidoreductase | / | 0.463 | |
| 2woa | 576 | Macrophage metalloelastase | 3.4.24.65 | 0.463 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.463 | |
| 3hk1 | B64 | Fatty acid-binding protein, adipocyte | / | 0.463 | |
| 1szf | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.462 | |
| 2fzw | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.462 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.462 | |
| 2xs4 | ALA_PHE_THR | Karilysin | 3.4.24 | 0.462 | |
| 3ayk | CGS | Interstitial collagenase | 3.4.24.7 | 0.462 | |
| 3stw | 2TD | Methylketone synthase I | / | 0.462 | |
| 4prx | ADP | DNA gyrase subunit B | / | 0.462 | |
| 5aga | ANP | DNA polymerase theta | / | 0.462 | |
| 5fkl | TDC | Tetracycline repressor protein class D | / | 0.462 | |
| 2e77 | FMN | Lactate oxidase | / | 0.461 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.461 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.461 | |
| 4cje | Q31 | Integrase | / | 0.461 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.461 | |
| 4z54 | GDP | Neuronal-specific septin-3 | / | 0.461 | |
| 5dbj | FAD | FADH2-dependent halogenase PltA | / | 0.461 | |
| 1fxs | NAP | GDP-L-fucose synthase | / | 0.460 | |
| 1gz8 | MBP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.460 | |
| 1r6u | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.460 | |
| 2w6o | OA3 | Biotin carboxylase | 6.3.4.14 | 0.460 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.460 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.460 | |
| 3img | BZ3 | Pantothenate synthetase | 6.3.2.1 | 0.460 | |
| 3mk6 | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.460 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.460 | |
| 4fwf | FAD | Lysine-specific histone demethylase 1B | 1 | 0.460 | |
| 4l1f | COS | Acyl-CoA dehydrogenase domain protein | / | 0.460 | |
| 4uoc | NCN | CinA-like protein | / | 0.460 | |
| 2xq0 | BES | Leukotriene A-4 hydrolase homolog | 3.3.2.6 | 0.459 | |
| 2z4s | ADP | Chromosomal replication initiator protein DnaA | / | 0.459 | |
| 3abx | RCB | Glucanase | / | 0.459 | |
| 3b2e | ADP | ATPase GET3 | / | 0.459 | |
| 3jzd | NAD | Maleylacetate reductase | / | 0.459 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.459 | |
| 5cdt | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.459 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.459 | |
| 5kcz | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.459 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.458 | |
| 1gox | FMN | Peroxisomal (S)-2-hydroxy-acid oxidase | 1.1.3.15 | 0.458 | |
| 3bgx | TMP | Thymidylate synthase | / | 0.458 | |
| 3fst | FAD | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.458 | |
| 3hj9 | FMN | Uncharacterized protein | / | 0.458 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 3nd6 | ATP | Phosphopantetheine adenylyltransferase | / | 0.458 | |
| 4cr8 | NAD | N-acylmannosamine 1-dehydrogenase | 1.1.1.233 | 0.458 | |
| 4tln | LNO | Thermolysin | 3.4.24.27 | 0.458 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.457 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.457 | |
| 1npt | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.457 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.457 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.457 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.457 | |
| 2r8o | T5X | Transketolase 1 | / | 0.457 | |
| 2rl1 | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.457 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.457 | |
| 3pd2 | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.457 | |
| 3r83 | Z14 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.457 | |
| 3tvu | B37 | Acetyl-CoA carboxylase | / | 0.457 | |
| 4fv7 | E94 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.457 | |
| 4gj3 | 0XP | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.457 | |
| 5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.457 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.456 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.456 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.456 | |
| 1u3c | FAD | Cryptochrome-1 | / | 0.456 | |
| 1u4d | DBQ | Activated CDC42 kinase 1 | / | 0.456 | |
| 2fn7 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.456 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.456 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 3f2p | S3B | Thermolysin | 3.4.24.27 | 0.456 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.456 | |
| 3gnw | XNC | Genome polyprotein | 2.7.7.48 | 0.456 | |
| 3t1t | GDP | Probable gliding protein mglA | / | 0.456 | |
| 3tz3 | B36 | Acetyl-CoA carboxylase | / | 0.456 | |
| 3w32 | W32 | Epidermal growth factor receptor | 2.7.10.1 | 0.456 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.456 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.456 | |
| 4guy | KLJ | Macrophage metalloelastase | 3.4.24.65 | 0.456 | |
| 4i6a | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.456 | |
| 4l4f | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 1edo | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic | 1.1.1.100 | 0.455 | |
| 1kfb | IGP | Tryptophan synthase alpha chain | / | 0.455 | |
| 1kor | ANP | Argininosuccinate synthase | / | 0.455 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.455 | |
| 1wk8 | VMS | Isoleucine--tRNA ligase | 6.1.1.5 | 0.455 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.455 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.455 | |
| 2p9c | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.455 | |
| 2x3f | APC | Pantothenate synthetase | / | 0.455 | |
| 2y8l | ADP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.455 | |
| 3g5q | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.455 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.455 | |
| 4bup | SAM | Histone-lysine N-methyltransferase KMT5B | 2.1.1.43 | 0.455 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.455 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.455 | |
| 5ej4 | TD6 | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.455 | |
| 5kjc | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.455 | |
| 1fcb | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.454 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.454 | |
| 1w5t | ANP | ORC1-type DNA replication protein 2 | / | 0.454 | |
| 2i7p | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.454 | |
| 2jah | NDP | Clavaldehyde dehydrogenase | / | 0.454 | |
| 3ckq | UPG | Glucosyl-3-phosphoglycerate synthase | 2.4.1.266 | 0.454 | |
| 3fsu | FAD | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.454 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.454 | |
| 3vcy | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.454 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.454 | |
| 4bva | T3 | Ketimine reductase mu-crystallin | 1.5.1.25 | 0.454 | |
| 4jbs | P52 | Endoplasmic reticulum aminopeptidase 2 | 3.4.11 | 0.454 | |
| 4uir | FAD | Oleate hydratase | 4.2.1.53 | 0.454 | |
| 4xg1 | LLP | Diaminopimelate decarboxylase | / | 0.454 | |
| 5ebu | FMN | Lactate oxidase | / | 0.454 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.453 | |
| 1nfr | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.453 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 1svm | ATP | Large T antigen | 3.6.4 | 0.453 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 2tmn | 0FA | Thermolysin | 3.4.24.27 | 0.453 | |
| 3bbr | BHY | Glutamate receptor 2 | / | 0.453 | |
| 3enk | UPG | UDP-glucose 4-epimerase | / | 0.453 | |
| 3ieu | GDP | GTPase Era | / | 0.453 | |
| 3kji | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.453 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.453 | |
| 3zvm | ADP | Bifunctional polynucleotide phosphatase/kinase | 2.7.1.78 | 0.453 | |
| 4ng2 | OHN | Transcriptional activator protein LasR | / | 0.453 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.453 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.452 | |
| 1guy | NAD | Malate dehydrogenase | / | 0.452 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.452 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 1i7g | AZ2 | Peroxisome proliferator-activated receptor alpha | / | 0.452 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.452 | |
| 1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.452 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.452 | |
| 1yqy | 915 | Lethal factor | 3.4.24.83 | 0.452 | |
| 2a2c | ADP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.452 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.452 | |
| 2viy | VG3 | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.452 | |
| 3f28 | S7B | Thermolysin | 3.4.24.27 | 0.452 | |
| 3i0a | DBH | Neutrophil gelatinase-associated lipocalin | / | 0.452 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.452 | |
| 3wyc | NAP | Meso-diaminopimelate D-dehydrogenase | 1.4.1.16 | 0.452 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 4lol | 1YE | Stimulator of interferon genes protein | / | 0.452 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.452 | |
| 4ww0 | ADP | ATP-dependent zinc metalloprotease FtsH | / | 0.452 | |
| 4yqf | GDP | Septin-9 | / | 0.452 | |
| 1d5j | MM3 | Stromelysin-1 | 3.4.24.17 | 0.451 | |
| 1got | GDP | Guanine nucleotide-binding protein G(t) subunit alpha-1 | / | 0.451 | |
| 1jk3 | BAT | Macrophage metalloelastase | 3.4.24.65 | 0.451 | |
| 1kbi | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.451 | |
| 1llu | NAD | Alcohol dehydrogenase | / | 0.451 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.451 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.451 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.451 | |
| 2ow0 | 6MR | Matrix metalloproteinase-9 | 3.4.24.35 | 0.451 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 3coy | 53H | Pantothenate synthetase | 6.3.2.1 | 0.451 | |
| 3dm6 | 757 | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 3mje | NDP | AmphB | / | 0.451 | |
| 3qj0 | QI3 | Botulinum neurotoxin type A | 3.4.24.69 | 0.451 | |
| 3vv8 | B02 | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.451 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 4ck2 | NVU | Integrase | / | 0.451 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.451 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.451 | |
| 4u2t | FAD | Cholesterol oxidase | 1.1.3.6 | 0.451 | |
| 4wuo | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.451 | |
| 5c2t | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.451 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.451 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.451 | |
| 1jdt | MTA | Purine nucleoside phosphorylase | / | 0.450 | |
| 1jue | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.450 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.450 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.450 | |
| 1ypk | CCR | Prothrombin | 3.4.21.5 | 0.450 | |
| 2a2d | ANP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.450 | |
| 2brb | PFQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.450 | |
| 2gnh | H52 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.450 | |
| 2zdy | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.450 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.450 | |
| 3a1c | ACP | Probable copper-exporting P-type ATPase A | 3.6.3.54 | 0.450 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 3il1 | B5D | Glutamate receptor 2 | / | 0.450 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.450 | |
| 3ioc | A5D | Pantothenate synthetase | 6.3.2.1 | 0.450 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.450 | |
| 3pb3 | SAH | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.450 | |
| 4a0r | DTB | Bifunctional dethiobiotin synthetase/7,8-diamino-pelargonic acid aminotransferase, mitochondrial | 6.3.3.3 | 0.450 | |
| 4h4u | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.450 | |
| 4r3a | RBF | Blue-light-activated histidine kinase 2 | 2.7.13.3 | 0.450 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 1n2e | APC | Pantothenate synthetase | 6.3.2.1 | 0.449 | |
| 1nhh | ANP | DNA mismatch repair protein MutL | / | 0.449 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.449 | |
| 2a84 | ATP | Pantothenate synthetase | 6.3.2.1 | 0.449 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.449 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 2yoz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.449 | |
| 3c8a | ARG_ARG_GLY_LEU_NH2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.449 | |
| 3cvk | N34 | Genome polyprotein | 2.7.7.48 | 0.449 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.449 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 3qiy | QI1 | Botulinum neurotoxin type A | 3.4.24.69 | 0.449 | |
| 3rue | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.449 | |
| 4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.449 | |
| 4lxa | 1YS | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 4tmn | 0PK | Thermolysin | 3.4.24.27 | 0.449 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.449 | |
| 4ycp | FMN | tRNA-dihydrouridine(16) synthase | / | 0.449 | |
| 5a3c | NAD | SIR2 family protein | / | 0.449 | |
| 1a8p | FAD | Ferredoxin--NADP reductase | / | 0.448 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1mv8 | GDX | GDP-mannose 6-dehydrogenase | 1.1.1.132 | 0.448 | |
| 1nfy | RTR | Coagulation factor X | 3.4.21.6 | 0.448 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.448 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.448 | |
| 1zp4 | FAD | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.448 | |
| 2bfo | NDP | Pteridine reductase 1 | 1.5.1.33 | 0.448 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.448 | |
| 2j4z | 626 | Aurora kinase A | 2.7.11.1 | 0.448 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 2y6d | TQJ | Matrilysin | 3.4.24.23 | 0.448 | |
| 3cow | 52H | Pantothenate synthetase | 6.3.2.1 | 0.448 | |
| 3cvu | FAD | RE11660p | / | 0.448 | |
| 3f1k | NAP | Uncharacterized oxidoreductase YciK | 1 | 0.448 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.448 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 3rq6 | APR | ADP-dependent (S)-NAD(P)H-hydrate dehydratase | / | 0.448 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 4tta | FMC | Purine nucleoside phosphorylase DeoD-type | / | 0.448 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.448 | |
| 1b4p | GPS | Glutathione S-transferase Mu 2 | / | 0.447 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.447 | |
| 1n2i | PAJ | Pantothenate synthetase | 6.3.2.1 | 0.447 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.447 | |
| 1ypg | UIR | Prothrombin | 3.4.21.5 | 0.447 | |
| 2b4r | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.447 | |
| 2g76 | NAD | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.447 | |
| 2hu6 | 37A | Macrophage metalloelastase | 3.4.24.65 | 0.447 | |
| 2iib | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.447 | |
| 2vet | UMP | Thymidylate synthase | / | 0.447 | |
| 2vtt | LZD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 2xpu | TDC | Tetracycline repressor protein class D | / | 0.447 | |
| 3lzw | NAP | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.447 | |
| 3qih | FG7 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 3r6s | CMP | CRP-like cAMP-activated global transcriptional regulator | / | 0.447 | |
| 4dd8 | BAT | Disintegrin and metalloproteinase domain-containing protein 8 | 3.4.24 | 0.447 | |
| 4dfg | 0JV | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 4die | C5P | Cytidylate kinase | / | 0.447 | |
| 4jau | ADP | Sensor histidine kinase | / | 0.447 | |
| 4mlp | 2CX | Cryptochrome-2 | / | 0.447 | |
| 5a3b | APR | SIR2 family protein | / | 0.447 | |
| 5a9s | NAP | Putative dehydrogenase | / | 0.447 | |
| 1b3d | S27 | Stromelysin-1 | 3.4.24.17 | 0.446 | |
| 1fdu | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.446 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.446 | |
| 1il0 | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.446 | |
| 1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.446 | |
| 1rpn | NDP | GDP-mannose 4,6-dehydratase | / | 0.446 | |
| 1xva | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.446 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 2d0o | ADP | Diol dehydratase-reactivating factor alpha subunit | / | 0.446 | |
| 2pak | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.446 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.446 | |
| 2r7p | ANP | Non-structural protein 2 | 3.6.4 | 0.446 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.446 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 2xpv | MIY | Tetracycline repressor protein class D | / | 0.446 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.446 | |
| 3bsa | 1PD | Genome polyprotein | 2.7.7.48 | 0.446 | |
| 3dey | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.446 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.446 | |
| 3gwd | NAP | Cyclohexanone monooxygenase | / | 0.446 | |
| 3klm | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.446 | |
| 3mel | TPP | Thiamin pyrophosphokinase family protein | / | 0.446 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.446 | |
| 3oq6 | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.446 | |
| 3utg | FDA | UDP-galactopyranose mutase | / | 0.446 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.446 | |
| 4b8m | VX6 | Aurora kinase B-A | 2.7.11.1 | 0.446 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 4bzb | DGT | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.446 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.446 | |
| 4ef8 | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.446 | |
| 4u9y | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.446 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.446 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.445 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.445 | |
| 1n6l | GTP | Ras-related protein Rab-5A | / | 0.445 | |
| 1ork | ATC | Tetracycline repressor protein class D | / | 0.445 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 1sdw | IYT | Peptidyl-glycine alpha-amidating monooxygenase | 1.14.17.3 | 0.445 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.445 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 2aqj | FAD | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.445 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.445 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.445 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.445 | |
| 2xhd | 7T9 | Glutamate receptor 2 | / | 0.445 | |
| 2ydd | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.445 | |
| 2yyi | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.445 | |
| 2zjm | F1M | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 3c89 | ARG_ARG_GLY_MET_NH2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.445 | |
| 3ebi | BEY | M1 family aminopeptidase | 3.4.11 | 0.445 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.445 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.445 | |
| 3o26 | NDP | Salutaridine reductase | / | 0.445 | |
| 3orz | BI4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.445 | |
| 3pgx | NAD | Uncharacterized NAD-dependent oxidoreductase MAP_4146 | / | 0.445 | |
| 3r7k | FDA | Probable acyl CoA dehydrogenase | / | 0.445 | |
| 3tr0 | 5GP | Guanylate kinase | / | 0.445 | |
| 3vsw | R31 | Renin | 3.4.23.15 | 0.445 | |
| 4dh6 | 0KN | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.445 | |
| 5kje | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.445 | |
| 1a9c | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.444 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.444 | |
| 1i24 | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.444 | |
| 1i59 | ADP | Chemotaxis protein CheA | 2.7.13.3 | 0.444 | |
| 1iid | NHM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.444 | |
| 1kc1 | NDP | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.444 | |
| 1xdp | ATP | Polyphosphate kinase | / | 0.444 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 2bjh | FER | Feruloyl esterase A | 3.1.1.73 | 0.444 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 2djl | FMN | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.444 | |
| 2ex1 | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.444 | |
| 2fhl | BNI | Avidin-related protein 4/5 | / | 0.444 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.444 | |
| 2ogy | C2F | 5-methyltetrahydrofolate:corrinoid/iron-sulfur protein co-methyltransferase | 2.1.1.258 | 0.444 | |
| 2v4l | ABJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 2zdx | P4A | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.444 | |
| 3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.444 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 3pce | 3HP | Protocatechuate 3,4-dioxygenase alpha chain | 1.13.11.3 | 0.444 | |
| 3pce | 3HP | Protocatechuate 3,4-dioxygenase beta chain | 1.13.11.3 | 0.444 | |
| 3w8f | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.444 | |
| 3zdf | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.444 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 4cfa | WOP | Integrase | / | 0.444 | |
| 4gll | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.444 | |
| 4gr3 | R45 | Macrophage metalloelastase | 3.4.24.65 | 0.444 | |
| 4iax | LIZ | Neutrophil gelatinase-associated lipocalin | / | 0.444 | |
| 4jic | FMN | GTN Reductase | / | 0.444 | |
| 4ntd | FAD | Thioredoxin reductase | / | 0.444 | |
| 4rrg | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.444 | |
| 4tm0 | FAD | KtzI | / | 0.444 | |
| 4yvj | SFG | tRNA (guanine-N(1)-)-methyltransferase | 2.1.1.228 | 0.444 | |
| 5cku | FAD | L-ornithine N(5)-monooxygenase | / | 0.444 | |
| 5eja | TD6 | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.444 | |
| 5hwo | HMG | Hydroxymethylglutaryl-CoA synthase | / | 0.444 | |
| 1d0l | BLG | Membrane-bound lytic murein transglycosylase B | 4.2.2.n1 | 0.443 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.443 | |
| 1jdv | ADN | Purine nucleoside phosphorylase | / | 0.443 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.443 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.443 | |
| 1u8v | FAD | 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase | / | 0.443 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.443 | |
| 2ejz | SAH | Diphthine synthase | / | 0.443 | |
| 2fmo | FAD | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.443 | |
| 2fxv | 5GP | Xanthine phosphoribosyltransferase | 2.4.2.22 | 0.443 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.443 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.443 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 2o7o | DXT | Tetracycline repressor protein class D | / | 0.443 | |
| 2p5f | SAH | Diphthine synthase | / | 0.443 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.443 | |
| 2tps | TPS | Thiamine-phosphate synthase | / | 0.443 | |
| 2w13 | WR2 | Snake venom metalloproteinase BaP1 | 3.4.24 | 0.443 | |
| 2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.443 | |
| 2xyu | Q9G | Ephrin type-A receptor 4 | 2.7.10.1 | 0.443 | |
| 3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.443 | |
| 3bts | NAD | Galactose/lactose metabolism regulatory protein GAL80 | / | 0.443 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.443 | |
| 3py0 | SU9 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 3tne | RIT | Candidapepsin-1 | 3.4.23.24 | 0.443 | |
| 4a9r | RU5 | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.443 | |
| 4b66 | NAP | L-ornithine N(5)-monooxygenase | / | 0.443 | |
| 4bao | MVF | Prothrombin | 3.4.21.5 | 0.443 | |
| 4dpw | AGS | Mevalonate diphosphate decarboxylase | / | 0.443 | |
| 4f65 | 0S9 | Fibroblast growth factor receptor 1 | / | 0.443 | |
| 4l7f | 1V5 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.443 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.443 | |
| 1het | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.442 | |
| 1i3m | UD1 | UDP-glucose 4-epimerase | / | 0.442 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.442 | |
| 1ur5 | NAD | Malate dehydrogenase | / | 0.442 | |
| 1v9a | SAH | Uncharacterized protein | / | 0.442 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.442 | |
| 2dft | ADP | Shikimate kinase | 2.7.1.71 | 0.442 | |
| 2e9u | A25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 2ovx | 4MR | Matrix metalloproteinase-9 | 3.4.24.35 | 0.442 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.442 | |
| 2wzm | NA7 | Uncharacterized oxidoreductase MSMEG_2407/MSMEI_2346 | / | 0.442 | |
| 2xgs | 44P | Uncharacterized protein | / | 0.442 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.442 | |
| 2zvb | SAH | Precorrin-3 C17-methyltransferase | / | 0.442 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 3bg7 | FAD | Pyranose 2-oxidase | / | 0.442 | |
| 3cf0 | ADP | Transitional endoplasmic reticulum ATPase | 3.6.4.6 | 0.442 | |
| 3cnj | FAD | Cholesterol oxidase | 1.1.3.6 | 0.442 | |
| 3cso | XNI | Genome polyprotein | 2.7.7.48 | 0.442 | |
| 3dag | FEG | 5,10-methenyltetrahydromethanopterin hydrogenase | 1.12.98.2 | 0.442 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3geg | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.442 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.442 | |
| 3kh5 | ADP | Uncharacterized protein MJ1225 | / | 0.442 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.442 | |
| 3pe2 | E1B | Casein kinase II subunit alpha | 2.7.11.1 | 0.442 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.442 | |
| 3uay | ADN | Purine nucleoside phosphorylase DeoD-type | / | 0.442 | |
| 4bri | UNP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.442 | |
| 4dpu | AGS | Mevalonate diphosphate decarboxylase | / | 0.442 | |
| 4e4q | RRH | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.442 | |
| 4fj2 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.442 | |
| 4gcm | FAD | Thioredoxin reductase | 1.8.1.9 | 0.442 | |
| 4jld | ADP | Adenylate kinase | / | 0.442 | |
| 4mkh | AP5 | Adenylate kinase | / | 0.442 | |
| 4mzu | TYD | WxcM-like protein | / | 0.442 | |
| 4n4v | 2GY | Tankyrase-1 | 2.4.2.30 | 0.442 | |
| 4qxp | 1YE | Stimulator of interferon genes protein | / | 0.442 | |
| 4u07 | ATP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.442 | |
| 5cdg | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.442 | |
| 1ae8 | AZL | Prothrombin | 3.4.21.5 | 0.441 | |
| 1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.441 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.441 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.441 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.441 | |
| 1gg5 | E09 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 1icv | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.441 | |
| 1qf2 | TI3 | Thermolysin | 3.4.24.27 | 0.441 | |
| 1w34 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.441 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.441 | |
| 2ow2 | 8MR | Matrix metalloproteinase-9 | 3.4.24.35 | 0.441 | |
| 2yki | YKI | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 2zz0 | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.441 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.441 | |
| 3c15 | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.441 | |
| 3jvv | ACP | Twitching mobility protein | / | 0.441 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.441 | |
| 3toh | 079 | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 3zhu | TD8 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.441 | |
| 3zsy | OM3 | Integrase | / | 0.441 | |
| 4cf1 | IY7 | Integrase | / | 0.441 | |
| 4imo | PWZ | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.441 | |
| 4kin | 1M8 | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 4qna | X11 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.441 | |
| 4w6z | 8ID | Alcohol dehydrogenase 1 | 1.1.1.1 | 0.441 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.441 | |
| 5doz | NDP | JamJ | / | 0.441 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.440 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.440 | |
| 1hyg | NAP | L-2-hydroxycarboxylate dehydrogenase (NAD(P)(+)) | / | 0.440 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.440 | |
| 1n9m | BTN | Streptavidin | / | 0.440 | |
| 1tf7 | ATP | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.440 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.440 | |
| 1zmd | NAI | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.440 | |
| 2anb | 5GP | Guanylate kinase | 2.7.4.8 | 0.440 | |
| 2brm | DFZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 2egl | SAH | Diphthine synthase | / | 0.440 | |
| 2eni | SAH | Diphthine synthase | / | 0.440 | |
| 2fvc | 888 | Polyprotein | / | 0.440 | |
| 2g78 | REA | Cellular retinoic acid-binding protein 2 | / | 0.440 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.440 | |
| 2gsd | NAD | Formate dehydrogenase | / | 0.440 | |
| 2izh | BTN | Streptavidin | / | 0.440 | |
| 2npx | NAD | NADH peroxidase | 1.11.1.1 | 0.440 | |
| 2pmo | HMD | Protein kinase 7 | / | 0.440 | |
| 2r2m | I50 | Prothrombin | 3.4.21.5 | 0.440 | |
| 2vd0 | D27 | Hematopoietic prostaglandin D synthase | / | 0.440 | |
| 2xx9 | 1NF | Glutamate receptor 2 | / | 0.440 | |
| 3ag6 | PAJ | Pantothenate synthetase | / | 0.440 | |
| 3clr | FAD | Electron transfer flavoprotein subunit alpha | / | 0.440 | |
| 3cos | NAD | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.440 | |
| 3fnl | SHA | Lactoperoxidase | / | 0.440 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.440 | |
| 3hdy | GDU | UDP-galactopyranose mutase | / | 0.440 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 3qql | X03 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.440 | |
| 3s8p | SAM | Histone-lysine N-methyltransferase KMT5B | 2.1.1.43 | 0.440 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.440 | |
| 4b64 | FAD | L-ornithine N(5)-monooxygenase | / | 0.440 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.440 | |
| 4fkz | UD1 | UDP-N-acetylglucosamine 2-epimerase | 5.1.3.14 | 0.440 | |
| 4fl3 | ANP | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.440 | |
| 4h8a | NAI | Ureidoglycolate dehydrogenase (NAD(+)) | 1.1.1.350 | 0.440 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.440 | |
| 4jlp | ADP | Adenylate kinase | / | 0.440 | |
| 4k5o | 1OT | M1 family aminopeptidase | 3.4.11 | 0.440 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.440 | |
| 4rrr | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.440 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.440 | |
| 4wdf | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.440 | |
| 4zgs | NAD | Putative D-lactate dehydrogenase | / | 0.440 | |
| 5kj6 | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.440 |