sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3d9z | D9Z | Carbonic anhydrase 2 | 4.2.1.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3d9z | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 1.000 | |
| 1bn1 | AL5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.853 | |
| 1bnn | AL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.822 | |
| 3daz | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.820 | |
| 1i91 | INQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.796 | |
| 1a42 | BZU | Carbonic anhydrase 2 | 4.2.1.1 | 0.779 | |
| 3dcc | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.771 | |
| 3k2f | NKX | Carbonic anhydrase 2 | 4.2.1.1 | 0.771 | |
| 1bnw | TPD | Carbonic anhydrase 2 | 4.2.1.1 | 0.765 | |
| 2h15 | B19 | Carbonic anhydrase 2 | 4.2.1.1 | 0.764 | |
| 3dc3 | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.760 | |
| 3qyk | IE2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.760 | |
| 1bnt | AL2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.758 | |
| 1bn4 | AL9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.756 | |
| 4ito | MPX | Carbonic anhydrase 2 | 4.2.1.1 | 0.753 | |
| 3po6 | DT9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.742 | |
| 4kap | 1QV | Carbonic anhydrase 2 | 4.2.1.1 | 0.734 | |
| 1kwr | SG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.732 | |
| 3eft | 3BS | Carbonic anhydrase 2 | 4.2.1.1 | 0.732 | |
| 3mhl | J71 | Carbonic anhydrase 2 | 4.2.1.1 | 0.719 | |
| 4ilx | 1EZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.713 | |
| 1g1d | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.709 | |
| 1i9n | IOA | Carbonic anhydrase 2 | 4.2.1.1 | 0.708 | |
| 4iwz | 1GO | Carbonic anhydrase 2 | 4.2.1.1 | 0.698 | |
| 3m5e | JDR | Carbonic anhydrase 2 | 4.2.1.1 | 0.696 | |
| 1zsb | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.695 | |
| 1if4 | FBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.694 | |
| 3d8w | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.693 | |
| 3n4b | WWZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.693 | |
| 4bf6 | X0Q | Carbonic anhydrase 2 | 4.2.1.1 | 0.693 | |
| 1bnu | AL3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.692 | |
| 4m2r | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.691 | |
| 1if5 | FBT | Carbonic anhydrase 2 | 4.2.1.1 | 0.690 | |
| 2h4n | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.690 | |
| 3mho | J43 | Carbonic anhydrase 2 | 4.2.1.1 | 0.688 | |
| 1i8z | INL | Carbonic anhydrase 2 | 4.2.1.1 | 0.687 | |
| 1g52 | F2B | Carbonic anhydrase 2 | 4.2.1.1 | 0.686 | |
| 3dcs | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.686 | |
| 3kig | DA4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.686 | |
| 3m67 | E36 | Carbonic anhydrase 2 | 4.2.1.1 | 0.685 | |
| 1cil | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.684 | |
| 3sbh | E65 | Carbonic anhydrase 2 | 4.2.1.1 | 0.683 | |
| 2weh | FB1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.681 | |
| 3bet | CTF | Carbonic anhydrase 2 | 4.2.1.1 | 0.681 | |
| 3ni5 | C1H | Carbonic anhydrase 2 | 4.2.1.1 | 0.677 | |
| 2eu3 | FF3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.675 | |
| 1bn3 | AL6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.674 | |
| 1if6 | FBU | Carbonic anhydrase 2 | 4.2.1.1 | 0.674 | |
| 1bnq | AL4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.673 | |
| 4n16 | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.673 | |
| 3t84 | SG6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.672 | |
| 3hku | TOR | Carbonic anhydrase 2 | 4.2.1.1 | 0.669 | |
| 2wej | FB2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.666 | |
| 4mo8 | 2VQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.666 | |
| 1g4o | BSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.665 | |
| 2x7t | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.665 | |
| 3mzc | S6I | Carbonic anhydrase 2 | 4.2.1.1 | 0.665 | |
| 3oyq | OYQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.661 | |
| 4itp | 1GD | Carbonic anhydrase 2 | 4.2.1.1 | 0.660 | |
| 1i90 | INM | Carbonic anhydrase 2 | 4.2.1.1 | 0.657 | |
| 3n0n | P9B | Carbonic anhydrase 2 | 4.2.1.1 | 0.657 | |
| 3igp | DT7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.656 | |
| 3m2n | J74 | Carbonic anhydrase 2 | 4.2.1.1 | 0.656 | |
| 3ml2 | SU0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.654 | |
| 3mna | DWH | Carbonic anhydrase 2 | 4.2.1.1 | 0.654 | |
| 3t82 | SG4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.652 | |
| 3b4f | TUO | Carbonic anhydrase 2 | 4.2.1.1 | 0.651 | |
| 3n2p | AYX | Carbonic anhydrase 2 | 4.2.1.1 | 0.651 | |
| 5flt | VJJ | Carbonic anhydrase 2 | 4.2.1.1 | 0.650 | |
| 4bf1 | 9FK | Carbonic anhydrase 2 | 4.2.1.1 | 0.649 | |
| 1kwq | SG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.648 | |
| 3dcw | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.648 | |
| 3dd8 | 2C7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.646 | |
| 3mhc | ARZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.646 | |
| 3oik | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.644 | |
| 1cnx | EG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.643 | |
| 2weg | FBV | Carbonic anhydrase 2 | 4.2.1.1 | 0.643 | |
| 3oys | OYS | Carbonic anhydrase 2 | 4.2.1.1 | 0.643 | |
| 4kni | E1E | Carbonic anhydrase 2 | 4.2.1.1 | 0.643 | |
| 3nb5 | R21 | Carbonic anhydrase 2 | 4.2.1.1 | 0.640 | |
| 3p5l | IT5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.639 | |
| 1ttm | 667 | Carbonic anhydrase 2 | 4.2.1.1 | 0.637 | |
| 3m40 | J45 | Carbonic anhydrase 2 | 4.2.1.1 | 0.637 | |
| 3dbu | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.634 | |
| 3m98 | E02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.634 | |
| 4k13 | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.634 | |
| 1xpz | 4TZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.633 | |
| 3oim | VZ5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.633 | |
| 1bnm | AL8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.630 | |
| 1if7 | SBR | Carbonic anhydrase 2 | 4.2.1.1 | 0.628 | |
| 2wd2 | MS5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.625 | |
| 4pxx | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.625 | |
| 1g4j | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.622 | |
| 3v2j | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.621 | |
| 1cny | EG3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.620 | |
| 3n3j | WWV | Carbonic anhydrase 2 | 4.2.1.1 | 0.619 | |
| 2weo | FBW | Carbonic anhydrase 2 | 4.2.1.1 | 0.617 | |
| 3f4x | KLT | Carbonic anhydrase 2 | 4.2.1.1 | 0.616 | |
| 3oy0 | OY0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.615 | |
| 3sax | E50 | Carbonic anhydrase 2 | 4.2.1.1 | 0.612 | |
| 3s8x | E59 | Carbonic anhydrase 2 | 4.2.1.1 | 0.610 | |
| 1g54 | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.609 | |
| 2x7u | WZA | Carbonic anhydrase 2 | 4.2.1.1 | 0.608 | |
| 4dz7 | D02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.606 | |
| 4m2v | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.604 | |
| 1bnv | AL7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.600 | |
| 3mdz | EZL | Carbonic anhydrase 7 | 4.2.1.1 | 0.600 | |
| 3mmf | D9H | Carbonic anhydrase 2 | 4.2.1.1 | 0.596 | |
| 4k0t | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.596 | |
| 1g45 | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.594 | |
| 3sbi | E90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.594 | |
| 3ffp | LC1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.593 | |
| 1okm | SAB | Carbonic anhydrase 2 | 4.2.1.1 | 0.591 | |
| 1i9p | IOE | Carbonic anhydrase 2 | 4.2.1.1 | 0.590 | |
| 3bl1 | BL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.590 | |
| 3l14 | I7B | Carbonic anhydrase 2 | 4.2.1.1 | 0.586 | |
| 1xq0 | 4TR | Carbonic anhydrase 2 | 4.2.1.1 | 0.584 | |
| 1okl | MNS | Carbonic anhydrase 2 | 4.2.1.1 | 0.580 | |
| 2q1q | OSP | Carbonic anhydrase 2 | 4.2.1.1 | 0.578 | |
| 3m96 | E38 | Carbonic anhydrase 2 | 4.2.1.1 | 0.578 | |
| 3t85 | SG7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.578 | |
| 3m2y | BE0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.576 | |
| 3mhi | J90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.575 | |
| 1jd0 | AZM | Carbonic anhydrase 12 | 4.2.1.1 | 0.574 | |
| 1rj6 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.573 | |
| 4ht2 | V50 | Carbonic anhydrase 12 | 4.2.1.1 | 0.571 | |
| 1cnw | EG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.567 | |
| 3s9t | E49 | Carbonic anhydrase 2 | 4.2.1.1 | 0.567 | |
| 3myq | E27 | Carbonic anhydrase 2 | 4.2.1.1 | 0.565 | |
| 4knj | E1F | Carbonic anhydrase 2 | 4.2.1.1 | 0.565 | |
| 1i9q | IOF | Carbonic anhydrase 2 | 4.2.1.1 | 0.562 | |
| 2pow | I7C | Carbonic anhydrase 2 | 4.2.1.1 | 0.561 | |
| 3f7u | AG4 | Carbonic anhydrase 4 | 4.2.1.1 | 0.555 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.554 | |
| 4kp8 | E1G | Carbonic anhydrase 12 | 4.2.1.1 | 0.551 | |
| 4lu3 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.544 | |
| 3dd0 | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.542 | |
| 4kp5 | E1F | Carbonic anhydrase 12 | 4.2.1.1 | 0.541 | |
| 1oq5 | CEL | Carbonic anhydrase 2 | 4.2.1.1 | 0.538 | |
| 3rz8 | RZ8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.538 | |
| 4k0z | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.534 | |
| 3f7b | AG5 | Carbonic anhydrase 4 | 4.2.1.1 | 0.533 | |
| 3znc | BZ1 | Carbonic anhydrase 4 | 4.2.1.1 | 0.531 | |
| 4uov | AZM | Carbonate dehydratase | / | 0.529 | |
| 3fw3 | ETS | Carbonic anhydrase 4 | 4.2.1.1 | 0.527 | |
| 1okn | STB | Carbonic anhydrase 2 | 4.2.1.1 | 0.526 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.522 | |
| 4x5s | AZM | Carbonic anhydrase (Carbonate dehydratase) | / | 0.520 | |
| 4knm | E1E | Carbonic anhydrase 13 | 4.2.1.1 | 0.511 | |
| 1if8 | SBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.509 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.508 | |
| 4hu1 | V13 | Carbonic anhydrase 13 | 4.2.1.1 | 0.503 | |
| 4knn | E1F | Carbonic anhydrase 13 | 4.2.1.1 | 0.503 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.500 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.500 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.498 | |
| 5fl4 | 9FK | Carbonic anhydrase 9 | 4.2.1.1 | 0.498 | |
| 3lxe | TOR | Carbonic anhydrase 1 | 4.2.1.1 | 0.497 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.496 | |
| 1eou | SMS | Carbonic anhydrase 2 | 4.2.1.1 | 0.495 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.494 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.494 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.489 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.489 | |
| 1q45 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.488 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.488 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.487 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.487 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.486 | |
| 4iae | 1DX | Alr2278 protein | / | 0.486 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.486 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.485 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.484 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.484 | |
| 1yda | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.482 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.482 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.482 | |
| 4jic | FMN | GTN Reductase | / | 0.482 | |
| 1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.481 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.481 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.481 | |
| 3zht | TD9 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.481 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.481 | |
| 4n1g | CEI | Obelin | / | 0.481 | |
| 5kgp | ACO | Predicted acetyltransferase | / | 0.481 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.478 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.477 | |
| 2yoz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.477 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.477 | |
| 3hgo | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.477 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.477 | |
| 4iah | 1DX | Alr2278 protein | / | 0.477 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.476 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.476 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.476 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.475 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.475 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.475 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.475 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.474 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.474 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.474 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.474 | |
| 3zs7 | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.474 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.473 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.472 | |
| 4c77 | N01 | Phenylacetone monooxygenase | 1.14.13.92 | 0.472 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.472 | |
| 1b5e | DCM | Deoxycytidylate 5-hydroxymethyltransferase | 2.1.2.8 | 0.471 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.471 | |
| 3zcn | ATP | Adenosine monophosphate-protein transferase SoFic | 2.7.7.n1 | 0.471 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.471 | |
| 1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.470 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.470 | |
| 3mla | JJZ | Probable nicotinate-nucleotide adenylyltransferase | / | 0.470 | |
| 4r81 | FMN | Predicted NADH dehydrogenase | / | 0.470 | |
| 2d3a | ADP | Glutamine synthetase root isozyme 3 | 6.3.1.2 | 0.469 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.469 | |
| 3hgr | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.469 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.469 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.469 | |
| 3t3q | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.469 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.469 | |
| 1akb | PPD | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.468 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.467 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.467 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.467 | |
| 3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.467 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.467 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.467 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.467 | |
| 1q20 | PLO | Sulfotransferase family cytosolic 2B member 1 | 2.8.2.2 | 0.466 | |
| 2hs6 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.466 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.466 | |
| 4fhf | 0TT | Spore photoproduct lyase | / | 0.466 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.466 | |
| 2q85 | 973 | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.465 | |
| 2r0c | FAD | Putative FAD-monooxygenase | / | 0.465 | |
| 3gka | FMN | N-ethylmaleimide reductase | / | 0.465 | |
| 4dbc | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.465 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.465 | |
| 4m0f | 1YK | Acetylcholinesterase | 3.1.1.7 | 0.465 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.464 | |
| 2nnq | T4B | Fatty acid-binding protein, adipocyte | / | 0.464 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.464 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.464 | |
| 5fd8 | A5A | Putative carboxypeptidase yocD | / | 0.464 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.464 | |
| 1akc | PPE | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.463 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.463 | |
| 1u0h | FOK | Adenylate cyclase type 2 | / | 0.463 | |
| 1u0h | FOK | Adenylate cyclase type 5 | / | 0.463 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.463 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.463 | |
| 2xtn | GTP | GTPase IMAP family member 2 | / | 0.463 | |
| 2zvc | SAH | Precorrin-3 C17-methyltransferase | / | 0.463 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.463 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.463 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.463 | |
| 4wdg | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.463 | |
| 1eio | GCH | Gastrotropin | / | 0.462 | |
| 1foa | UD1 | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | 2.4.1.101 | 0.462 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.462 | |
| 2vn1 | FK5 | Peptidylprolyl isomerase | / | 0.462 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
| 3v2u | ATP | Protein GAL3 | / | 0.462 | |
| 4lzw | THM | Uridine phosphorylase | / | 0.462 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.461 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.461 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.461 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.461 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.461 | |
| 3tvq | DQH | Multifunctional cyclase-dehydratase-3-O-methyl transferase TcmN | 2.1.1 | 0.461 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.461 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.461 | |
| 4yco | FMN | tRNA-dihydrouridine(16) synthase | / | 0.461 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.461 | |
| 1lwi | NAP | 3-alpha-hydroxysteroid dehydrogenase | 1.1.1.50 | 0.460 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.460 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.460 | |
| 2gev | COK | Pantothenate kinase | 2.7.1.33 | 0.460 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.460 | |
| 1cs4 | FOK | Adenylate cyclase type 2 | / | 0.459 | |
| 1cs4 | FOK | Adenylate cyclase type 5 | / | 0.459 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.459 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.459 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 3zhs | TD6 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.459 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.459 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.459 | |
| 4h6p | FMN | Chromate reductase | / | 0.459 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.459 | |
| 5a01 | 12V | O-glycosyltransferase | / | 0.459 | |
| 1f4e | TPR | Thymidylate synthase | / | 0.458 | |
| 1iqr | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.458 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.458 | |
| 1v35 | NAI | Enoyl-ACP reductase | / | 0.458 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.458 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.458 | |
| 2q3r | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.458 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.458 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.458 | |
| 3zbr | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.458 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.458 | |
| 4e2d | FMN | Dehydrogenase | / | 0.458 | |
| 4ejv | LCL | Transcriptional regulator TcaR | / | 0.458 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.458 | |
| 4oe4 | NAD | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial | 1.2.1.88 | 0.458 | |
| 4rvf | TYD | D-mycarose 3-C-methyltransferase | / | 0.458 | |
| 1u1g | BBB | Uridine phosphorylase | 2.4.2.3 | 0.457 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.457 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.457 | |
| 3faz | NOS | Purine nucleoside phosphorylase | / | 0.457 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.457 | |
| 3fr2 | 8CA | Fatty acid-binding protein, adipocyte | / | 0.457 | |
| 3hxc | BD6 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.457 | |
| 3zhq | TPP | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.457 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.457 | |
| 5c1d | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.457 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 1bl4 | AP1 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.456 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.456 | |
| 2q3o | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.456 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.456 | |
| 4ehy | ADP | Tetraacyldisaccharide 4'-kinase | / | 0.456 | |
| 4fhj | 0TZ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.456 | |
| 1eii | RTL | Retinol-binding protein 2 | / | 0.455 | |
| 1fml | RTL | Retinol dehydratase | / | 0.455 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.455 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.455 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 3mdd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.455 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 4hms | FMN | Phenazine biosynthesis protein PhzG | 1.4 | 0.455 | |
| 4tmb | FMN | Old yellow enzyme | / | 0.455 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.454 | |
| 1kbi | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.454 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.454 | |
| 2hs8 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.454 | |
| 2jj2 | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.454 | |
| 2uuo | LK3 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.454 | |
| 3qj0 | QI3 | Botulinum neurotoxin type A | 3.4.24.69 | 0.454 | |
| 3zhv | TDW | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.454 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.454 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 4bri | UNP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.454 | |
| 4dja | FAD | (6-4) photolyase | / | 0.454 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.454 | |
| 4wdf | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.454 | |
| 1ci0 | FMN | Pyridoxamine 5'-phosphate oxidase | 1.4.3.5 | 0.453 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.453 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.453 | |
| 1kvs | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.453 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.453 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.453 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.453 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.453 | |
| 2o12 | FMN | Chorismate synthase | / | 0.453 | |
| 2vtd | LKM | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.453 | |
| 2wqp | WQP | Polysialic acid capsule biosynthesis protein SiaC | / | 0.453 | |
| 2xpc | 051 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.453 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.453 | |
| 3qpg | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.453 | |
| 4cax | 646 | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.453 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.453 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.453 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.453 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.452 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.452 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.452 | |
| 2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.452 | |
| 2npi | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.452 | |
| 3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.452 | |
| 3ed1 | GA3 | Gibberellin receptor GID1 | / | 0.452 | |
| 3mau | EXT | Putative sphingosine-1-phosphate lyase | / | 0.452 | |
| 3qvr | FAD | Glucose oxidase | 1.1.3.4 | 0.452 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.452 | |
| 3zvm | ADP | Bifunctional polynucleotide phosphatase/kinase | 2.7.1.78 | 0.452 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.452 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.452 | |
| 4rvg | TYD | D-mycarose 3-C-methyltransferase | / | 0.452 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.451 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.451 | |
| 1zbd | GTP | Ras-related protein Rab-3A | / | 0.451 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.451 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.451 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.451 | |
| 4giu | 636 | Anthranilate phosphoribosyltransferase | / | 0.451 | |
| 4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.451 | |
| 4jbs | P52 | Endoplasmic reticulum aminopeptidase 2 | 3.4.11 | 0.451 | |
| 4jtq | NAP | Aldo-keto reductase family 1 member C2 | / | 0.451 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.451 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.451 | |
| 4xnw | 2ID | P2Y purinoceptor 1 | / | 0.451 | |
| 1c7o | PPG | Hemolysin | / | 0.450 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.450 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.450 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.450 | |
| 2qc8 | ADP | Glutamine synthetase | 6.3.1.2 | 0.450 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.450 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.450 | |
| 2vte | IK4 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.450 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.450 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.450 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.450 | |
| 3mj4 | FAD | UDP-galactopyranose mutase | / | 0.450 | |
| 3p2o | NAD | Bifunctional protein FolD | / | 0.450 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.450 | |
| 3uu1 | 14B | Anthranilate phosphoribosyltransferase | / | 0.450 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.450 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.450 | |
| 4bfy | ZVY | Pantothenate kinase | 2.7.1.33 | 0.450 | |
| 4boe | CLR | Japanin | / | 0.450 | |
| 4kln | AGS | Transitional endoplasmic reticulum ATPase | 3.6.4.6 | 0.450 | |
| 4x7z | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.450 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.449 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.449 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.449 | |
| 2i9k | SAH | Modification methylase HhaI | 2.1.1.37 | 0.449 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.449 | |
| 2lba | CHO | Fatty acid binding protein 6 | / | 0.449 | |
| 2pob | GW4 | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 2qw0 | 34Z | 4-chlorobenzoyl CoA ligase | / | 0.449 | |
| 2v4l | ABJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 2x0i | NAI | Malate dehydrogenase | / | 0.449 | |
| 2zs8 | ADP | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 3a6r | FMN | FMN-binding protein | / | 0.449 | |
| 3mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.449 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.449 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.449 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.449 | |
| 4v12 | POG | MaoC like domain protein | / | 0.449 | |
| 5eio | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.449 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.448 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.448 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.448 | |
| 1xva | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.448 | |
| 2a84 | ATP | Pantothenate synthetase | 6.3.2.1 | 0.448 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.448 | |
| 2uup | LK4 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.448 | |
| 3m2v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.448 | |
| 3mfl | DHY | Protocatechuate 3,4-dioxygenase alpha chain | 1.13.11.3 | 0.448 | |
| 3mfl | DHY | Protocatechuate 3,4-dioxygenase beta chain | 1.13.11.3 | 0.448 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.448 | |
| 4a6r | TA8 | Probable aminotransferase | / | 0.448 | |
| 4bf9 | FMN | tRNA-dihydrouridine(16) synthase | / | 0.448 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.448 | |
| 4usq | FAD | Pyridine nucleotide-disulfide oxidoreductase | / | 0.448 | |
| 4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.448 | |
| 4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.448 | |
| 4zj8 | SUV | Orexin receptor type 1 | / | 0.448 | |
| 1gal | FAD | Glucose oxidase | 1.1.3.4 | 0.447 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1m8k | NAD | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.447 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.447 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.447 | |
| 2idk | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.447 | |
| 2rtm | IMI | Streptavidin | / | 0.447 | |
| 3isj | A8D | Pantothenate synthetase | 6.3.2.1 | 0.447 | |
| 3m30 | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.447 | |
| 3m30 | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.447 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.447 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.447 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.447 | |
| 4jq4 | IMN | Aldo-keto reductase family 1 member C2 | / | 0.447 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.447 | |
| 4u7w | NDP | MxaA | / | 0.447 | |
| 5jy1 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.447 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.446 | |
| 1icq | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.446 | |
| 1nzx | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.446 | |
| 1odj | GMP | Purine nucleoside phosphorylase | / | 0.446 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.446 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.446 | |
| 2fy4 | COA | Choline O-acetyltransferase | 2.3.1.6 | 0.446 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.446 | |
| 2xuq | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3iqi | ASN_GLU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.446 | |
| 3ksq | Z96 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.446 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.446 | |
| 3p84 | FMN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.446 | |
| 3t64 | DU3 | Deoxyuridine 5'-triphosphate nucleotidohydrolase | / | 0.446 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.446 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.446 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.446 | |
| 4i13 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.446 | |
| 5a3c | NAD | SIR2 family protein | / | 0.446 | |
| 6std | MS2 | Scytalone dehydratase | 4.2.1.94 | 0.446 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.445 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.445 | |
| 1m8j | NAD | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.445 | |
| 1toj | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.445 | |
| 1vji | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.445 | |
| 2avx | HTF | Regulatory protein SdiA | / | 0.445 | |
| 2v58 | LZJ | Biotin carboxylase | 6.3.4.14 | 0.445 | |
| 2vrb | NAP | Triphenylmethane reductase | / | 0.445 | |
| 2zcv | NDP | Quinone oxidoreductase 2 | 1.6.5.2 | 0.445 | |
| 3da2 | 4MD | Carbonic anhydrase 13 | 4.2.1.1 | 0.445 | |
| 3e33 | ED7 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.445 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.445 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.445 | |
| 4eb5 | PLP | Cysteine desulfurase IscS 2 | / | 0.445 | |
| 4g6g | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.445 | |
| 4v2g | ITC | Tetracycline repressor protein class D | / | 0.445 | |
| 5fsi | 8DG | 7,8-dihydro-8-oxoguanine triphosphatase | 3.6.1.55 | 0.445 | |
| 1dds | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.444 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 1t91 | GTP | Ras-related protein Rab-7a | / | 0.444 | |
| 2brb | PFQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 2g26 | 3LG | Renin | 3.4.23.15 | 0.444 | |
| 2oc4 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.444 | |
| 2r59 | PH0 | Leukotriene A-4 hydrolase | 3.3.2.6 | 0.444 | |
| 2xwe | AMF | Glucosylceramidase | 3.2.1.45 | 0.444 | |
| 2yp0 | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.444 | |
| 2yxu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.444 | |
| 3arv | SAU | Chitinase A | / | 0.444 | |
| 3c15 | FOK | Adenylate cyclase type 2 | / | 0.444 | |
| 3c15 | FOK | Adenylate cyclase type 5 | / | 0.444 | |
| 3c35 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.444 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.444 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3nl6 | TPS | Uncharacterized protein | / | 0.444 | |
| 3own | 3OX | Renin | 3.4.23.15 | 0.444 | |
| 3zhr | TPP | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.444 | |
| 3zhu | TD8 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.444 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.444 | |
| 4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 4kfq | KFQ | Glutamate receptor ionotropic, NMDA 1 | / | 0.444 | |
| 1a5b | IGP | Tryptophan synthase alpha chain | / | 0.443 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.443 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 1yry | MSG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.443 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2bxo | OPB | Serum albumin | / | 0.443 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.443 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.443 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 3a6q | FMN | FMN-binding protein | / | 0.443 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.443 | |
| 3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.443 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 3sl2 | ATP | Sensor histidine kinase WalK | / | 0.443 | |
| 3udq | 09E | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.443 | |
| 4g2r | H1L | Probable propionyl-CoA carboxylase beta chain 6 | 6.4.1.3 | 0.443 | |
| 4hy6 | FJ1 | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 4m49 | 22Y | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.443 | |
| 4pt0 | NAD | Aldehyde dehydrogenase | / | 0.443 | |
| 4rnw | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.443 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.442 | |
| 1j37 | X8Z | Angiotensin-converting enzyme | 3.4.15.1 | 0.442 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 2gna | GDU | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.442 | |
| 2ibz | UQ6 | Cytochrome b | / | 0.442 | |
| 2vqo | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.442 | |
| 2y1t | DUD | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.442 | |
| 2zsi | GA4 | Gibberellin receptor GID1A | 3 | 0.442 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.442 | |
| 3fr4 | F8A | Fatty acid-binding protein, adipocyte | / | 0.442 | |
| 3hcr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.442 | |
| 3mk6 | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.442 | |
| 3ruh | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.442 | |
| 3u9e | COA | Lmo1369 protein | / | 0.442 | |
| 4ca8 | 3ES | Angiotensin-converting enzyme | 3.4.15.1 | 0.442 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.442 | |
| 4l1x | NAP | Aldo-keto reductase family 1 member C2 | / | 0.442 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.442 | |
| 4prx | ADP | DNA gyrase subunit B | / | 0.442 | |
| 4rww | 2BA | Lmo2692 protein | / | 0.442 | |
| 4tx9 | AMZ | Phosphoribosyl isomerase A | / | 0.442 | |
| 4ycp | FMN | tRNA-dihydrouridine(16) synthase | / | 0.442 | |
| 5c80 | URI | Uridine phosphorylase | / | 0.442 | |
| 5ftc | ADP | TPR domain protein | / | 0.442 | |
| 4s0v | SUV | Orexin receptor type 2 | / | 0.442 | |
| 1bdm | NAX | Malate dehydrogenase | / | 0.441 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.441 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 1i59 | ADP | Chemotaxis protein CheA | 2.7.13.3 | 0.441 | |
| 1u1d | 181 | Uridine phosphorylase | 2.4.2.3 | 0.441 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.441 | |
| 1xuz | MMN | Capsule biosynthesis protein | / | 0.441 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.441 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.441 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.441 | |
| 2vjm | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.441 | |
| 2yim | MC4 | Probable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase ) | / | 0.441 | |
| 2z1q | FAD | Acyl-CoA dehydrogenase | / | 0.441 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.441 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.441 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3eej | 53R | Uncharacterized protein | / | 0.441 | |
| 3hdy | GDU | UDP-galactopyranose mutase | / | 0.441 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 3pm1 | ET | HTH-type transcriptional regulator QacR | / | 0.441 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.441 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.441 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.441 | |
| 4gyz | D5M | Tyrosyl-DNA phosphodiesterase 2 | 3.1.4 | 0.441 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.441 | |
| 4yj2 | GTP | Tubulin alpha-1B chain | / | 0.441 | |
| 4yp6 | NAP | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.441 | |
| 1b5d | DCM | Deoxycytidylate 5-hydroxymethyltransferase | 2.1.2.8 | 0.440 | |
| 1cq7 | PY5 | Aspartate aminotransferase | 2.6.1.1 | 0.440 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1r2j | FAD | FkbI | / | 0.440 | |
| 1rx0 | FAD | Isobutyryl-CoA dehydrogenase, mitochondrial | 1.3.99 | 0.440 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.440 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.440 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 2bik | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 2get | COK | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 2j08 | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.440 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.440 | |
| 3w6h | AZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.440 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.440 | |
| 4ej1 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 4f7i | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.440 | |
| 4fgc | PQ0 | NADPH-dependent 7-cyano-7-deazaguanine reductase | 1.7.1.13 | 0.440 | |
| 4ips | 1G4 | Mycocyclosin synthase | 1.14.21.9 | 0.440 | |
| 4lh7 | 1X8 | DNA ligase | / | 0.440 | |
| 4rp8 | ASC | Ascorbate-specific PTS system EIIC component | / | 0.440 | |
| 4x81 | MVI | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.440 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.440 | |
| 4yao | FMN | NADPH--cytochrome P450 reductase | / | 0.440 |