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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3autNAIGlucose 1-dehydrogenase 41.1.1.47

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3autNAIGlucose 1-dehydrogenase 41.1.1.471.000
1geeNADGlucose 1-dehydrogenase1.1.1.470.621
1gcoNADGlucose 1-dehydrogenase1.1.1.470.620
1g6kNADGlucose 1-dehydrogenase1.1.1.470.617
1rwbNADGlucose 1-dehydrogenase1.1.1.470.606
3toxNAPPutative oxidoreductase/0.595
4dbzNDPPutative ketoacyl reductase1.3.10.588
4yagNAIC alpha-dehydrogenase/0.587
2ztmNADD(-)-3-hydroxybutyrate dehydrogenase/0.576
4hwkNAPSepiapterin reductase1.1.1.1530.567
4j7xNAPSepiapterin reductase1.1.1.1530.567
3vdqNAD3-hydroxybutyrate dehydrogenase/0.565
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.562
1u7tNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.560
4dc0NDPPutative ketoacyl reductase1.3.10.560
4yaiNAIC alpha-dehydrogenase/0.560
3w8eNAD3-hydroxybutyrate dehydrogenase/0.557
2c29NAPDihydroflavonol 4-reductase/0.555
2q2vNADBeta-D-hydroxybutyrate dehydrogenase/0.553
4j7uNAPSepiapterin reductase1.1.1.1530.553
3p19NDPPutative blue fluorescent protein/0.552
4gh5NADShort-chain dehydrogenase/reductase SDR/0.552
5jlaNADPutative short-chain dehydrogenase/reductase/0.552
2dteNAIGlucose 1-dehydrogenase related protein/0.550
1w4zNAPPutative ketoacyl reductase1.3.10.548
1ae1NAPTropinone reductase 1/0.547
2dknNAI3-alpha-hydroxysteroid dehydrogenase/0.547
1ipeNDPTropinone reductase 21.1.1.2360.546
1x7gNAPPutative ketoacyl reductase1.3.10.545
3w8fNAD3-hydroxybutyrate dehydrogenase/0.545
2wsbNADGalactitol dehydrogenase/0.543
4fw8NAI3-oxoacyl-(Acyl-carrier-protein) reductase/0.543
5jydNADShort chain dehydrogenase/0.542
5jsfNAD17-beta-hydroxysteroid dehydrogenase 141.1.10.540
2ag5NAD3-hydroxybutyrate dehydrogenase type 2/0.539
1iy8NADLevodione reductase/0.537
2o23NAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.537
2wdzNADGalactitol dehydrogenase/0.537
3ijrNADOxidoreductase, short chain dehydrogenase/reductase family/0.537
4z3dNDPCarbonyl reductase [NADPH] 11.1.1.1840.537
4bmsNAPAlclohol dehydrogenase/short-chain dehydrogenase/0.535
1n5dNDPCarbonyl reductase [NADPH] 1/0.534
4dc1NDPPutative ketoacyl reductase1.3.10.534
2gdzNAD15-hydroxyprostaglandin dehydrogenase [NAD(+)]1.1.1.1410.533
4k6fNAPPutative Acetoacetyl-CoA reductase/0.533
2bd0NAPSepiapterin reductase/0.531
3d3wNAPL-xylulose reductase1.1.1.100.531
2b4qNAPRhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase1.1.1.1000.530
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.530
1gegNADDiacetyl reductase [(S)-acetoin forming]1.1.1.3040.529
1zemNADXylitol dehydrogenase/0.529
2nnlNAPDihydroflavonol 4-reductase1.1.1.2190.528
2y99NADCis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase1.3.1.560.528
2ydxNAPMethionine adenosyltransferase 2 subunit beta/0.528
3rkuNAPNADP-dependent 3-hydroxy acid dehydrogenase/0.528
1e6wNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.527
2ztlNADD(-)-3-hydroxybutyrate dehydrogenase/0.525
3lqfNADGalactitol dehydrogenase/0.525
1g0nNDPTetrahydroxynaphthalene reductase1.1.1.2520.523
4u7wNDPMxaA/0.522
2q2qNADBeta-D-hydroxybutyrate dehydrogenase/0.521
4fj1NAP17beta-hydroxysteroid dehydrogenase/0.521
4i5eNAPAlclohol dehydrogenase/short-chain dehydrogenase/0.521
1pr9NAPL-xylulose reductase1.1.1.100.520
3qwfNAP17beta-hydroxysteroid dehydrogenase/0.520
4hxyNDPPlm1/0.520
2jahNDPClavaldehyde dehydrogenase/0.519
2ztvNADD(-)-3-hydroxybutyrate dehydrogenase/0.519
1oaaNAPSepiapterin reductase1.1.1.1530.518
1u7tTDT3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.518
3bhiNAPCarbonyl reductase [NADPH] 11.1.1.1840.518
1e3sNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.517
1edoNAP3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic1.1.1.1000.516
4fn4NADShort chain dehydrogenase/0.516
5lc1NADL-threonine 3-dehydrogenase/0.516
1x7hNDPPutative ketoacyl reductase1.3.10.515
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.515
5idwNAPShort-chain dehydrogenase/reductase SDR/0.515
2yutNAPPutative short-chain oxidoreductase/0.513
1wntNAPL-xylulose reductase1.1.1.100.512
3o26NDPSalutaridine reductase/0.512
1mg5NAIAlcohol dehydrogenase1.1.1.10.510
5js6NAD17-beta-hydroxysteroid dehydrogenase 141.1.10.509
1e3wNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.508
3ai3NDPNADPH-sorbose reductase/0.508
3rucNADUDP-N-acetylglucosamine 4-epimerase/0.507
4b79NADProbable short-chain dehydrogenase/0.507
4fj2NAP17beta-hydroxysteroid dehydrogenase/0.507
4kwhNAPReductase homolog/0.507
3l77NJPShort-chain alcohol dehydrogenase/0.506
3wdsNADNADH-dependent quinuclidinone reductase/0.504
3a28NADL-2,3-butanediol dehydrogenase1.1.1.760.503
2ewmNAD(S)-1-Phenylethanol dehydrogenase1.1.1.3110.502
3f1kNAPUncharacterized oxidoreductase YciK10.502
3ak4NADNADH-dependent quinuclidinone reductase/0.500
3nugNADPyridoxal 4-dehydrogenase1.1.1.1070.500
3sjuNDPKeto reductase/0.500
4twrNADNAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase/0.500
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.500
3o4rNAPDehydrogenase/reductase SDR family member 41.1.1.1840.499
4o0lNDPNADPH-dependent 3-quinuclidinone reductase/0.499
3orfNADDihydropteridine reductase1.5.1.340.498
1vl8NAPOxidoreductase, short chain dehydrogenase/reductase family/0.497
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.497
1h5qNAPNADP-dependent mannitol dehydrogenase1.1.1.1380.496
4rf2NAPNADPH dependent R-specific alcohol dehydrogenase/0.496
3iahNAPPutative oxoacyl-(Acyl carrier protein) reductase/0.495
4xnw2IDP2Y purinoceptor 1/0.495
1bsvNDPGDP-L-fucose synthase/0.494
4esoNAPPutative oxidoreductase/0.494
2fzwNADAlcohol dehydrogenase class-31.1.1.10.493
3s55NADPutative short-chain dehydrogenase/reductase/0.493
1dhrNADDihydropteridine reductase1.5.1.340.492
2qs4LY5Glutamate receptor ionotropic, kainate 1/0.492
3lu1NADUDP-N-acetylglucosamine 4-epimerase/0.492
3ndrNADPyridoxal 4-dehydrogenase1.1.1.1070.491
3ru7NADUDP-N-acetylglucosamine 4-epimerase/0.489
3sj7NDP3-oxoacyl-(Acyl-carrier-protein) reductase, putative/0.489
2givACOHistone acetyltransferase KAT8/0.488
2il2LIXRenin3.4.23.150.488
3ggoNAIPrephenate dehydrogenase/0.488
3ai2NDPNADPH-sorbose reductase/0.487
4iqgNAPShort-chain dehydrogenase/reductase SDR/0.487
4nbwNADShort-chain dehydrogenase/reductase SDR/0.487
2vkeTACTetracycline repressor protein class D/0.486
2ekpNAD2-deoxy-D-gluconate 3-dehydrogenase/0.485
2q1wNADPutative nucleotide sugar epimerase/ dehydratase/0.485
3sx2NADUncharacterized protein/0.485
4fc7NAPPeroxisomal 2,4-dienoyl-CoA reductase1.3.1.340.485
1kvrNADUDP-glucose 4-epimerase5.1.3.20.484
4nbuNAI3-oxoacyl-(Acyl-carrier-protein) reductase/0.484
3kb6NADD-lactate dehydrogenase/0.483
4fj0NAP17beta-hydroxysteroid dehydrogenase/0.483
1snyNAPLD36273p/0.482
1xg5NAPDehydrogenase/reductase SDR family member 11/0.482
1cydNDPCarbonyl reductase [NADPH] 21.1.1.1840.481
1f8fNADBenzyl alcohol dehydrogenase/0.481
3ru9NADUDP-N-acetylglucosamine 4-epimerase/0.481
3o03NAPDehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase)/0.480
1e3eNAIAlcohol dehydrogenase 41.1.1.10.479
4is3NAD3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 21.17.98.10.479
1fxsNAPGDP-L-fucose synthase/0.478
1naiNADUDP-glucose 4-epimerase5.1.3.20.478
2hrbNAPCarbonyl reductase [NADPH] 31.1.1.1840.478
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.477
1xseNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.477
2qs3UBEGlutamate receptor ionotropic, kainate 1/0.477
3r6sCMPCRP-like cAMP-activated global transcriptional regulator/0.477
3rufNADUDP-N-acetylglucosamine 4-epimerase/0.477
4dmmNAP3-oxoacyl-[acyl-carrier-protein] reductase/0.477
1xkvATPPhosphoenolpyruvate carboxykinase (ATP)/0.476
3ruaNADUDP-N-acetylglucosamine 4-epimerase/0.476
4h8aNAIUreidoglycolate dehydrogenase (NAD(+))1.1.1.3500.476
5cdtNAJAlcohol dehydrogenase E chain1.1.1.10.476
1tehNADAlcohol dehydrogenase class-31.1.1.10.475
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.475
2hunNAD336aa long hypothetical dTDP-glucose 4,6-dehydratase/0.475
2ikuLIYRenin3.4.23.150.475
4b8zNAPGDP-L-fucose synthase1.1.1.2710.475
5einNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.475
2ejvNADL-threonine 3-dehydrogenase/0.474
2gcgNDPGlyoxylate reductase/hydroxypyruvate reductase1.1.1.790.474
3ruhNADUDP-N-acetylglucosamine 4-epimerase/0.474
5ig2NADShort-chain dehydrogenase/reductase SDR/0.474
2cmjNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.473
2gv8NDPThiol-specific monooxygenase1.14.130.473
3t4nADP5'-AMP-activated protein kinase subunit gamma/0.473
3tn7NJPShort-chain alcohol dehydrogenase/0.473
4yr9NADL-threonine 3-dehydrogenase, mitochondrial1.1.1.1030.473
1xe55FEPlasmepsin-23.4.23.390.472
3gy0NAPNAD(P)-dependent oxidoreductase/0.472
3qwbNDPProbable quinone oxidoreductase1.6.5.50.472
4idgNADPutative UDP-glucose 4-epimerase/0.472
2y0mACOHistone acetyltransferase KAT8/0.471
3lpjZ75Beta-secretase 13.4.23.460.471
3rueNADUDP-N-acetylglucosamine 4-epimerase/0.471
3uxyNADShort-chain dehydrogenase/reductase SDR/0.471
4cpdNADAlcohol dehydrogenase/0.471
4qecNAPElxO/0.471
1fk8NAD3-alpha-hydroxysteroid dehydrogenase/carbonyl reductase1.1.1.500.470
1hdrNADDihydropteridine reductase1.5.1.340.470
1nffNAD3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.470
1rx0FADIsobutyryl-CoA dehydrogenase, mitochondrial1.3.990.470
2g5cNADPrephenate dehydrogenase/0.470
4bb3KKAIsopenicillin N synthase1.21.3.10.470
3mjeNDPAmphB/0.469
4gllNADUDP-glucuronic acid decarboxylase 14.1.1.350.469
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.469
1ek5NADUDP-glucose 4-epimerase/0.468
2ou2ACOHistone acetyltransferase KAT5/0.468
2zatNAPDehydrogenase/reductase SDR family member 41.1.1.1840.468
2zb3NDPProstaglandin reductase 21.3.1.480.468
3rj5NADAlcohol dehydrogenase1.1.1.10.468
3rj9NADAlcohol dehydrogenase1.1.1.10.468
1kr2TADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.467
1ykfNAPNADP-dependent isopropanol dehydrogenase1.1.1.800.467
3aw9NADNAD-dependent epimerase/dehydratase/0.467
3docNADGlyceraldehyde-3-phosphate dehydrogenase/0.467
3rudNADUDP-N-acetylglucosamine 4-epimerase/0.467
4dwvNAJAlcohol dehydrogenase E chain1.1.1.10.467
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.467
1b15NAEAlcohol dehydrogenase1.1.1.10.466
1bxkNADdTDP-glucose 4,6-dehydratase 2/0.466
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.466
1hetNADAlcohol dehydrogenase E chain1.1.1.10.466
1i3lNADUDP-glucose 4-epimerase/0.466
1nahNADUDP-glucose 4-epimerase5.1.3.20.466
2bfqAR6[Protein ADP-ribosylglutamate] hydrolase AF_15213.2.20.466
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.466
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.466
3cosNADAlcohol dehydrogenase 41.1.1.10.466
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.466
3ms421NGlycogen phosphorylase, muscle form2.4.1.10.466
4b8wNAPGDP-L-fucose synthase1.1.1.2710.466
4mdhNADMalate dehydrogenase, cytoplasmic1.1.1.370.466
4n5nNAPAcetoacetyl-CoA reductase1.1.1.360.466
1sbyNADAlcohol dehydrogenase1.1.1.10.465
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.465
4l4xNDPAmphI/0.465
1e7qNAPGDP-L-fucose synthase/0.464
1i6xCMPcAMP-activated global transcriptional regulator CRP/0.464
1nfrNAD3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.464
3c3nFMNDihydroorotate dehydrogenase (fumarate)1.3.98.10.464
3fktSIIBeta-secretase 13.4.23.460.464
3kybFADUDP-galactopyranose mutase5.4.99.90.464
3pgxNADUncharacterized NAD-dependent oxidoreductase MAP_4146/0.464
3qrwNDPPutative ketoacyl reductase1.3.10.464
4bkqNAIEnoyl-[acyl-carrier-protein] reductase [NADH]/0.464
4jjiNADAlcohol dehydrogenase class-3/0.464
2yy7NADL-threonine dehydrogenase/0.463
3w8dNAD3-hydroxybutyrate dehydrogenase/0.463
4enhFVXCholesterol 24-hydroxylase/0.463
4ure1PSCyclohexanol dehydrogenase/0.463
1qorNDPQuinone oxidoreductase 1/0.462
1xkqNDPUncharacterized protein/0.462
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.462
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.462
2ooyATP5'-AMP-activated protein kinase subunit gamma/0.462
2p5uNADUDP-glucose 4-epimerase/0.462
2q1tNADPutative nucleotide sugar epimerase/ dehydratase/0.462
2rbeNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.462
3up4FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.462
4uwmFMN3,6-diketocamphane 1,6 monooxygenase1.14.130.462
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.462
5dmhADP3-oxo-tetronate kinase/0.462
5kjcNAJAlcohol dehydrogenase E chain1.1.1.10.462
1qrpHH0Pepsin A-43.4.23.10.461
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.461
4fco0U4Beta-secretase 13.4.23.460.461
1cdoNADAlcohol dehydrogenase 11.1.1.10.460
1h74ADPHomoserine kinase2.7.1.390.460
1n7hNDPGDP-mannose 4,6 dehydratase 24.2.1.470.460
1wn3HXCPhenylacetic acid degradation protein PaaI/0.460
2ahrNAPPyrroline-5-carboxylate reductase/0.460
2b4yAPRNAD-dependent protein deacylase sirtuin-5, mitochondrial/0.460
2gjlFMNNitronate monooxygenase1.13.12.160.460
2v58LZJBiotin carboxylase6.3.4.140.460
2vprTDCTetracycline repressor protein class H/0.460
2ztuNADD(-)-3-hydroxybutyrate dehydrogenase/0.460
3kgcLY7Glutamate receptor 2/0.460
4ng5NAJAlcohol dehydrogenase E chain1.1.1.10.460
4rvgTYDD-mycarose 3-C-methyltransferase/0.460
4z63ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.460
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.459
1ldeNADAlcohol dehydrogenase E chain1.1.1.10.459
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.459
2cvzNDP3-hydroxyisobutyrate dehydrogenase/0.459
2dgnDOIAdenylosuccinate synthetase isozyme 1/0.459
2gesCOKPantothenate kinase2.7.1.330.459
2gmhFADElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial1.5.5.10.459
3a4vNADNDP-sugar epimerase/0.459
3c1y2BADNA integrity scanning protein DisA/0.459
4ambDUDPutative glycosyl transferase/0.459
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.459
5jscFADPutative acyl-CoA dehydrogenase/0.459
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.458
2hsdNAD3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.458
2hydADPPutative multidrug export ATP-binding/permease protein SAV18663.6.30.458
3bmoNAPPteridine reductase/0.458
3djjFADGlutathione reductase, mitochondrial1.8.1.70.458
3nxxNDPDihydrofolate reductase1.5.1.30.458
3ohh3HHBeta-secretase 13.4.23.460.458
3qlsNDPDihydrofolate reductase1.5.1.30.458
3uylTYDProbable NDP-rhamnosyltransferase/0.458
5bt9NAP3-oxoacyl-(Acyl-carrier-protein) reductase/0.458
5irnADPNucleotide binding oligomerization domain containing 2/0.458
1g1aNADdTDP-glucose 4,6-dehydratase/0.457
1h51FMNPentaerythritol tetranitrate reductase/0.457
1n2sNAIdTDP-4-dehydrorhamnose reductase1.1.1.1330.457
2ixaNADAlpha-N-acetylgalactosaminidase3.2.1.490.457
3sxpNADADP-L-glycero-D-mannoheptose-6-epimerase/0.457
5c2tFADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/0.457
2c54NADGDP-mannose 3,5-epimerase5.1.3.180.456
2he5NDPAldo-keto reductase family 1 member C211.1.10.456
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.456
3k5c0BIBeta-secretase 13.4.23.460.456
4dxhNAJAlcohol dehydrogenase E chain1.1.1.10.456
4q71FADBifunctional protein PutA/0.456
5adhAPRAlcohol dehydrogenase E chain1.1.1.10.456
5c8wPCGcGMP-dependent protein kinase 22.7.11.120.456
1r2jFADFkbI/0.455
2bgmNAJSecoisolariciresinol dehydrogenase1.1.1.3310.455
4gz612VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.455
4r81FMNPredicted NADH dehydrogenase/0.455
5koiNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.455
1b16NAQAlcohol dehydrogenase1.1.1.10.454
1mczRMNBenzoylformate decarboxylase4.1.1.70.454
1mjbACOHistone acetyltransferase ESA1/0.454
2ivnANPtRNA N6-adenosine threonylcarbamoyltransferase/0.454
3a1nNADNDP-sugar epimerase/0.454
3clsFADElectron transfer flavoprotein subunit alpha/0.454
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.454
3g49NAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.454
4blrUTPNTPase P4/0.454
4dieC5PCytidylate kinase/0.454
4m83ERYOleandomycin glycosyltransferase2.4.10.454
4p63NADProbable deoxyhypusine synthase2.5.1.460.454
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.454
1dnpFADDeoxyribodipyrimidine photo-lyase4.1.99.30.453
1kvkATPMevalonate kinase2.7.1.360.453
2c12FADNitroalkane oxidase1.7.3.10.453
2v6gNAP3-oxo-Delta(4,5)-steroid 5-beta-reductase/0.453
2xpvMIYTetracycline repressor protein class D/0.453
3mt817TGlycogen phosphorylase, muscle form2.4.1.10.453
3o0o5ADVitamin B12-dependent ribonucleotide reductase/0.453
3qgf46FGenome polyprotein2.7.7.480.453
3w0jT08Vitamin D3 receptor/0.453
4bcaFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.453
4z24FADPutative GMC-type oxidoreductase R13510.453
5dbvCOAAldehyde Dehydrogenase/0.453
1bwsNDPGDP-L-fucose synthase/0.452
1fwkADPHomoserine kinase2.7.1.390.452
1nuuNADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.452
1rkxNADCDP-D-glucose-4,6-dehydratase/0.452
2a94AP0L-lactate dehydrogenase1.1.1.270.452
2c20NADUDP-glucose 4-epimerase/0.452
2fj1CTCTetracycline repressor protein class D/0.452
2ignFADPyranose 2-oxidase/0.452
2qn7HBZGlycogen phosphorylase, muscle form2.4.1.10.452
2xlpFADPutative flavin-containing monooxygenase/0.452
3p62FMNPentaerythritol tetranitrate reductase/0.452
3ukfFDAUDP-galactopyranose mutase/0.452
4yxm2BADNA integrity scanning protein DisA/0.452
1hszNADAlcohol dehydrogenase 1B1.1.1.10.451
1i2bNADUDP-sulfoquinovose synthase, chloroplastic3.13.1.10.451
2abjCBCBranched-chain-amino-acid aminotransferase, cytosolic2.6.1.420.451
3ig6438Urokinase-type plasminogen activator3.4.21.730.451
3jv7NADSecondary alcohol dehydrogenase/0.451
3uceNDPDehydrogenase/0.451
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.451
1bil0IURenin3.4.23.150.450
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.450
1h63FMNPentaerythritol tetranitrate reductase/0.450
1pqc444Oxysterols receptor LXR-beta/0.450
1psa0ZLPepsin A3.4.23.10.450
1u3dFADCryptochrome-1/0.450
2g247IGRenin3.4.23.150.450
2ph6712Beta-secretase 13.4.23.460.450
3cinNADMyo-inositol-1-phosphate synthase-related protein/0.450
3hazFADBifunctional protein PutA/0.450
3mk6ACOPantothenate kinase 32.7.1.330.450
3u4cNDPNADPH-dependent reductase BacG/0.450
3zbrNAP2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.450
4fdnFADDecaprenylphosphoryl-beta-D-ribose oxidase/0.450
4fqsLYAThymidylate synthase ThyA/0.450
4gyy12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.450
4i02CMPcAMP-activated global transcriptional regulator CRP/0.450
4tqgNDPPutative dTDP-d-glucose 4 6-dehydratase/0.450
5jy1NADPutative short-chain dehydrogenase/reductase/0.450
5kj6NAJAlcohol dehydrogenase E chain1.1.1.10.450
1dbvNADGlyceraldehyde-3-phosphate dehydrogenase/0.449
1gqtACPRibokinase/0.449
1gzuNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.449
1mp0NADAlcohol dehydrogenase class-31.1.1.10.449
1o0sNAINAD-dependent malic enzyme, mitochondrial1.1.1.380.449
1tqf32PBeta-secretase 13.4.23.460.449
2ifaFMNUncharacterized protein/0.449
2w3bNDPDihydrofolate reductase1.5.1.30.449
2wf4ZY4Beta-secretase 13.4.23.460.449
2zvbSAHPrecorrin-3 C17-methyltransferase/0.449
3bg7FADPyranose 2-oxidase/0.449
3btsNADGalactose/lactose metabolism regulatory protein GAL80/0.449
4mo2FADUDP-galactopyranose mutase/0.449
5fs7FADApoptosis-inducing factor 1, mitochondrial1.1.10.449
5kjfNAJAlcohol dehydrogenase E chain1.1.1.10.449
1h50FMNPentaerythritol tetranitrate reductase/0.448
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.448
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.448
1qx4FADNADH-cytochrome b5 reductase 31.6.2.20.448
1tezFADDeoxyribodipyrimidine photo-lyase4.1.99.30.448
1vsoAT1Glutamate receptor ionotropic, kainate 1/0.448
1yqxNAPSinapyl alcohol dehydrogenase/0.448
2b3dFADModulator of drug activity B/0.448
2h55DZ8Heat shock protein HSP 90-alpha/0.448
2ktdPUCProstaglandin-H2 D-isomerase5.3.99.20.448
2oahQINBeta-secretase 13.4.23.460.448
2rcyNAPPyrroline-5-carboxylate reductase/0.448
2xx91NFGlutamate receptor 2/0.448
3d91REMRenin3.4.23.150.448
3lpiZ74Beta-secretase 13.4.23.460.448
3phiNDPShikimate dehydrogenase (NADP(+))/0.448
3qvpFADGlucose oxidase1.1.3.40.448
3uqdADPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.448
3zcsCAWGlycogen phosphorylase, muscle form2.4.1.10.448
4g7gVFVLanosterol 14-alpha-demethylase/0.448
4gid0GHBeta-secretase 13.4.23.460.448
4n82FMNRibonucleotide reductase (NrdI family protein), putative/0.448
4opgFDAConserved Archaeal protein/0.448
5kcpNAJAlcohol dehydrogenase E chain1.1.1.10.448
5kjeNAJAlcohol dehydrogenase E chain1.1.1.10.448
1aa6MGDFormate dehydrogenase H1.1.99.330.447
1egdFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.447
1k7l544Peroxisome proliferator-activated receptor alpha/0.447
1mj9COAHistone acetyltransferase ESA1/0.447
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.447
1vyrFMNPentaerythritol tetranitrate reductase/0.447
2bi7FADUDP-galactopyranose mutase5.4.99.90.447
2bjhFERFeruloyl esterase A3.1.1.730.447
2x0rNADMalate dehydrogenase/0.447
2x86NAPADP-L-glycero-D-manno-heptose-6-epimerase/0.447
2zsaADPPantothenate kinase2.7.1.330.447
3tscNADUncharacterized protein/0.447
3ukoNADAlcohol dehydrogenase class-3/0.447
4jtqNAPAldo-keto reductase family 1 member C2/0.447
4lisNADUDP-glucose 4-epimerase (Eurofung)/0.447
4u8oFDAUDP-galactopyranose mutase/0.447
4uymVOR14-alpha sterol demethylase Cyp51B/0.447
4xo7NAPAldo-keto reductase family 1 member C2/0.447
5d3qGDPDynamin-13.6.5.50.447
5kj1NAJAlcohol dehydrogenase E chain1.1.1.10.447
1cg3IMOAdenylosuccinate synthetase/0.446
1dirNADDihydropteridine reductase1.5.1.340.446
1drhNAPDihydrofolate reductase1.5.1.30.446
1ja0FMNNADPH--cytochrome P450 reductase/0.446
1lf3EH5Plasmepsin-23.4.23.390.446
1p0fNAPNADP-dependent alcohol dehydrogenase1.1.1.20.446
2d8aNADL-threonine 3-dehydrogenase/0.446
2fapRADPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.446
2fapRADSerine/threonine-protein kinase mTOR2.7.11.10.446
2ojtUBAGlutamate receptor ionotropic, kainate 1/0.446
2vijC44Beta-secretase 13.4.23.460.446
2xpwOTCTetracycline repressor protein class D/0.446
2ywwATPAspartate carbamoyltransferase regulatory chain/0.446
3eheNADUDP-glucose 4-epimerase (GalE-1)/0.446
3f3sNADLambda-crystallin homolog/0.446
3gw9VNILanosterol 14-alpha-demethylase/0.446
3hmvHBTcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.446
3jqpA2PFerredoxin--NADP reductase, apicoplast/0.446
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.446
3mw9NAIGlutamate dehydrogenase 1, mitochondrial1.4.1.30.446
3ogwIMNLactoperoxidase1.11.1.70.446
4dpi0N1Beta-secretase 13.4.23.460.446
4gl4NAIAlcohol dehydrogenase class-3/0.446
1fy7COAHistone acetyltransferase ESA1/0.445
1ib0NADNADH-cytochrome b5 reductase 31.6.2.20.445
1ib6NADMalate dehydrogenase/0.445
1jmhUMPThymidylate synthase/0.445
1kc1NDPdTDP-4-dehydrorhamnose reductase1.1.1.1330.445
1me6IVSPlasmepsin-23.4.23.390.445
1np7FADCryptochrome DASH/0.445
1nsgRADPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.445
1nsgRADSerine/threonine-protein kinase mTOR2.7.11.10.445
1t9gFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.445
1v0jFADUDP-galactopyranose mutase5.4.99.90.445
1yqdNAPSinapyl alcohol dehydrogenase/0.445
2d4vNADIsocitrate dehydrogenase [NADP]/0.445
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
2fznFADBifunctional protein PutA1.5.5.20.445
2hdjNDPAldo-keto reductase family 1 member C2/0.445
2iviACWIsopenicillin N synthase1.21.3.10.445
2viyVG3Beta-secretase 13.4.23.460.445
3oq6NAJAlcohol dehydrogenase E chain1.1.1.10.445
3w0gW07Vitamin D3 receptor/0.445
4dfg0JVGag-Pol polyprotein3.4.23.160.445
4nmdFDABifunctional protein PutA/0.445
4rheFMNFlavin prenyltransferase UbiX/0.445
4tm0FADKtzI/0.445
4u03GTPCyclic GMP-AMP synthase/0.445
4udrFAD5-(hydroxymethyl)furfural oxidase/0.445
4yntFDAGlucose oxidase, putative/0.445
1d0mBLGMembrane-bound lytic murein transglycosylase B4.2.2.n10.444
1udyFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.444
1zp3FAD5,10-methylenetetrahydrofolate reductase1.5.1.200.444
2b8l5HABeta-secretase 13.4.23.460.444
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.444
2fzmFADBifunctional protein PutA1.5.5.20.444
2gevCOKPantothenate kinase2.7.1.330.444
2j4dFADCryptochrome DASH, chloroplastic/mitochondrial/0.444
2q3eNAIUDP-glucose 6-dehydrogenase1.1.1.220.444
2qn3F55Glycogen phosphorylase, muscle form2.4.1.10.444
3dh9FADThioredoxin reductase 1, mitochondrial1.8.1.90.444
3dmeFADPutative conserved exported protein/0.444
3fapARDPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.444
3fapARDSerine/threonine-protein kinase mTOR2.7.11.10.444
3fsuFAD5,10-methylenetetrahydrofolate reductase1.5.1.200.444
3ieuGDPGTPase Era/0.444
4fhd0TTSpore photoproduct lyase/0.444
4xguADPPutative pachytene checkpoint protein 2/0.444
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.443
1ma0NADAlcohol dehydrogenase class-31.1.1.10.443
1rx1NAPDihydrofolate reductase1.5.1.30.443
1uy8PU5Heat shock protein HSP 90-alpha/0.443
2c1zU2FAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.443
2ebaFADPutative glutaryl-CoA dehydrogenase/0.443
2eeqSAHDiphthine synthase/0.443
2fn7NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.443
2is0I03Beta-secretase 13.4.23.460.443
2iyfERYOleandomycin glycosyltransferase2.4.10.443
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.443
2pa3NAID-3-phosphoglycerate dehydrogenase1.1.1.950.443
2wf1ZY1Beta-secretase 13.4.23.460.443
2xpuTDCTetracycline repressor protein class D/0.443
3cib314Beta-secretase 13.4.23.460.443
3he3FADUDP-galactopyranose mutase/0.443
3ixj586Beta-secretase 13.4.23.460.443
3sglFADtRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC/0.443
3tjzGNPADP-ribosylation factor 1/0.443
3to6LYS_CMCHistone acetyltransferase ESA1/0.443
3utgFDAUDP-galactopyranose mutase/0.443
3wd9QPCcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.443
4d89BXDBeta-secretase 13.4.23.460.443
4dh60KNBeta-secretase 13.4.23.460.443
4eakATP5'-AMP-activated protein kinase subunit gamma-1/0.443
4oztP1AEcdysone receptor, putative/0.443
4uocNCNCinA-like protein/0.443
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.443
5dp2NAPCurF/0.443
5er0FADUncharacterized NAD(FAD)-dependent dehydrogenase/0.443
1dxyNADD-2-hydroxyisocaproate dehydrogenase1.1.10.442
1nuqNXXNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.442
1sq5ADPPantothenate kinase2.7.1.330.442
1xddAAYIntegrin alpha-L/0.442
1ybaNADD-3-phosphoglycerate dehydrogenase1.1.1.950.442
2b37NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
3atzFMNProstaglandin F2a synthase/0.442
3cb2GDPTubulin gamma-1 chain/0.442
3mdvCL6Cholesterol 24-hydroxylase/0.442
3oetNADErythronate-4-phosphate dehydrogenase/0.442
3r7kFDAProbable acyl CoA dehydrogenase/0.442
3rpeFADPutative modulator of drug activity/0.442
3te5NAI5'-AMP-activated protein kinase subunit gamma/0.442
3vyeVYERenin3.4.23.150.442
4bcrWY1Peroxisome proliferator-activated receptor alpha/0.442
4bquCLRJapanin/0.442
4fapARDPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.442
4fapARDSerine/threonine-protein kinase mTOR2.7.11.10.442
4weqNAPNAD-dependent dehydrogenase/0.442
1cf3FADGlucose oxidase1.1.3.40.441
1e5qNDPSaccharopine dehydrogenase [NADP(+), L-glutamate-forming]1.5.1.100.441
1lwiNAP3-alpha-hydroxysteroid dehydrogenase1.1.1.500.441
1mjaCOAHistone acetyltransferase ESA1/0.441
1sowNADL-lactate dehydrogenase1.1.1.270.441
2dshSAHDiphthine synthase/0.441
3dghFADThioredoxin reductase 1, mitochondrial1.8.1.90.441
3dm6757Beta-secretase 13.4.23.460.441
3etdNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.441
3f03FMNPentaerythritol tetranitrate reductase/0.441
3lzxFADFerredoxin--NADP reductase 21.18.1.20.441
3oqkS52Renin3.4.23.150.441
3s5wFADL-ornithine N(5)-monooxygenase/0.441
4f9gC2EStimulator of interferon genes protein/0.441
4lcjNADC-terminal-binding protein 2/0.441
4m9aFDAAcyl-CoA dehydrogenase/0.441
5cdgNAJAlcohol dehydrogenase E chain1.1.1.10.441
1f06NDPMeso-diaminopimelate D-dehydrogenase1.4.1.160.440
1gpdNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.440
1ib0FADNADH-cytochrome b5 reductase 31.6.2.20.440
1ndhFADNADH-cytochrome b5 reductase 31.6.2.20.440
1nqoNADGlyceraldehyde-3-phosphate dehydrogenase/0.440
1txzAPRProbable ADP-ribose 1''-phosphate phosphatase YML087W3.1.3.840.440
1wvgAPRCDP-glucose 4,6-dehydratase4.2.1.450.440
2c59NADGDP-mannose 3,5-epimerase5.1.3.180.440
2iko7IGRenin3.4.23.150.440
3ab1FADFerredoxin--NADP reductase1.18.1.20.440
3c3xNAPEugenol synthase 11.1.1.3180.440
3cid318Beta-secretase 13.4.23.460.440
3fr8NDPKetol-acid reductoisomerase, chloroplastic1.1.1.860.440
3go4SAHUncharacterized protein/0.440
3hbbNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.440
3kej3EJCollagenase 33.4.240.440
3koyZ97D-ornithine 4,5-aminomutase subunit beta/0.440
3m0oFADMonomeric sarcosine oxidase1.5.3.10.440
3qvwNADMyo-inositol-1-phosphate synthase (Ino1)/0.440
3zw9NADPeroxisomal bifunctional enzyme1.1.1.350.440
4d86ADPPoly [ADP-ribose] polymerase 142.4.2.300.440
4dpf0LGBeta-secretase 13.4.23.460.440
4i6aHMG3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.440
4k9h1QUBeta-secretase 13.4.23.460.440
4opiFDAConserved Archaeal protein/0.440
5kczNAJAlcohol dehydrogenase E chain1.1.1.10.440