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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2ohvNHLGlutamate racemase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2ohvNHLGlutamate racemase/1.000
1bwsNDPGDP-L-fucose synthase/0.515
1h50FMNPentaerythritol tetranitrate reductase/0.512
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.494
3p62FMNPentaerythritol tetranitrate reductase/0.494
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.493
2abbFMNPentaerythritol tetranitrate reductase/0.493
4jicFMNGTN Reductase/0.492
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.489
3p67FMNPentaerythritol tetranitrate reductase/0.489
2uxoTACHTH-type transcriptional regulator TtgR/0.488
2ejvNADL-threonine 3-dehydrogenase/0.487
3p74FMNPentaerythritol tetranitrate reductase/0.487
4nwzFADFAD-dependent pyridine nucleotide-disulfide oxidoreductase/0.487
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.486
1h74AGSHomoserine kinase2.7.1.390.486
1h73ANPHomoserine kinase2.7.1.390.485
3f03FMNPentaerythritol tetranitrate reductase/0.485
3oqkS52Renin3.4.23.150.483
1xe55FEPlasmepsin-23.4.23.390.482
3atzFMNProstaglandin F2a synthase/0.480
1f8fNADBenzyl alcohol dehydrogenase/0.479
1tehNADAlcohol dehydrogenase class-31.1.1.10.479
3hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.479
4nd3NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.479
1e3eNAIAlcohol dehydrogenase 41.1.1.10.476
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.476
2hs8FMN12-oxophytodienoate reductase 31.3.1.420.476
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.476
1m13HYFNuclear receptor subfamily 1 group I member 2/0.475
2vn0TDZCytochrome P450 2C8/0.475
2xviFADPutative flavin-containing monooxygenase/0.475
3ibqATPPyridoxal kinase/0.475
3lqfNADGalactitol dehydrogenase/0.475
4uymVOR14-alpha sterol demethylase Cyp51B/0.475
1h63FMNPentaerythritol tetranitrate reductase/0.474
3d8vUD1Bifunctional protein GlmU/0.474
4q71FADBifunctional protein PutA/0.474
4v2gITCTetracycline repressor protein class D/0.474
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.473
1rneC60Renin3.4.23.150.473
3ctyFADProbable thioredoxin reductase/0.473
4enhFVXCholesterol 24-hydroxylase/0.473
2qbuSAHPrecorrin-2 methyltransferase/0.472
3gfbNADL-threonine 3-dehydrogenase/0.472
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.472
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.472
1h74ADPHomoserine kinase2.7.1.390.471
5a9sNAPPutative dehydrogenase/0.471
5d3qGDPDynamin-13.6.5.50.471
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.470
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.470
3otwCOAPhosphopantetheine adenylyltransferase/0.470
3s1dZIRCytokinin dehydrogenase 11.5.99.120.470
4q73FADBifunctional protein PutA/0.470
4rnuFMNNADPH dehydrogenase 11.6.99.10.470
4zjuNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.470
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.469
1p31EPUUDP-N-acetylmuramate--L-alanine ligase6.3.2.80.469
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.469
3f63GTXGlutathione transferase GST1-4/0.469
3p82FMNPentaerythritol tetranitrate reductase/0.469
3rudNADUDP-N-acetylglucosamine 4-epimerase/0.469
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.469
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.468
1nzdUPGDNA beta-glucosyltransferase/0.468
1xddAAYIntegrin alpha-L/0.468
2pxaSAHGenome polyprotein2.7.7.480.468
3gggNADPrephenate dehydrogenase/0.468
3gwfFADCyclohexanone monooxygenase/0.468
4gavFADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.468
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.467
1lsjNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.467
2he5NDPAldo-keto reductase family 1 member C211.1.10.467
3c1y2BADNA integrity scanning protein DisA/0.467
3l0lHC3Nuclear receptor ROR-gamma/0.467
3rpeFADPutative modulator of drug activity/0.467
4fw8NAI3-oxoacyl-(Acyl-carrier-protein) reductase/0.467
1j49NADD-lactate dehydrogenase1.1.1.280.466
1vyrFMNPentaerythritol tetranitrate reductase/0.466
2p5uNADUDP-glucose 4-epimerase/0.466
2q85973UDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.466
2qc8ADPGlutamine synthetase6.3.1.20.466
2zbaZBATrichothecene 3-O-acetyltransferase/0.466
3atyFMNProstaglandin F2a synthase/0.466
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.466
3h3r14HCollagen type IV alpha-3-binding protein/0.466
3h3t16HCollagen type IV alpha-3-binding protein/0.466
4a87NARMajor pollen allergen Bet v 1-A/0.466
4ambDUDPutative glycosyl transferase/0.466
4eywL0RCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.466
1f4eTPRThymidylate synthase/0.465
2hs6FMN12-oxophytodienoate reductase 31.3.1.420.465
3hgoFMN12-oxophytodienoate reductase 31.3.1.420.465
4g7gVFVLanosterol 14-alpha-demethylase/0.465
4oxyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.465
5itzLOCTubulin beta-2B chain/0.465
2lfoGCHFatty acid-binding protein, liver/0.464
3flkNAITartrate dehydrogenase/decarboxylase1.1.1.930.464
3kpkFADSulfide-quinone reductase/0.464
3p3zP3ZPutative cytochrome P450/0.464
3te5NAI5'-AMP-activated protein kinase subunit gamma/0.464
4g3sUD1Bifunctional protein GlmU/0.464
4g74FADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.464
4qq3XMPInosine-5'-monophosphate dehydrogenase/0.464
2f4bEHAPeroxisome proliferator-activated receptor gamma/0.463
3nl6TPSUncharacterized protein/0.463
3t2kFADSulfide-quinone reductase/0.463
4e2dFMNDehydrogenase/0.463
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.463
4nmdFDABifunctional protein PutA/0.463
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.463
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.463
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.462
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.462
2dfvNADL-threonine 3-dehydrogenase/0.462
2q3rFMN12-oxophytodienoate reductase 11.3.1.420.462
2znq401Peroxisome proliferator-activated receptor delta/0.462
3d4pNADL-lactate dehydrogenase 11.1.1.270.462
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.462
3zhqTPPMultifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.462
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.462
4xwtU5PRibonuclease J/0.462
1gpdNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.461
1ja1FMNNADPH--cytochrome P450 reductase/0.461
2rh9IGPTryptophan synthase alpha chain/0.461
2uagUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.461
2y8lADP5'-AMP-activated protein kinase subunit gamma-1/0.461
3aezGDPPantothenate kinase2.7.1.330.461
3d84NDPDihydrofolate reductase1.5.1.30.461
3ixp834Ecdysone receptor/0.461
3tjzGNPADP-ribosylation factor 1/0.461
4b722FBBeta-secretase 13.4.23.460.461
4xcvNDPProbable hydroxyacid dehydrogenase protein/0.461
1bil0IURenin3.4.23.150.460
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.460
1psa0ZLPepsin A3.4.23.10.460
1qyw5SDEstradiol 17-beta-dehydrogenase 11.1.1.620.460
1xe65FPPlasmepsin-23.4.23.390.460
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.460
2jcvNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.460
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.460
3b6zCO7Enoyl reductase LovC10.460
3b70NAPEnoyl reductase LovC10.460
3own3OWRenin3.4.23.150.460
4cdmFO1Deoxyribodipyrimidine photolyase/0.460
4ck2NVUIntegrase/0.460
4e2bFMNDehydrogenase/0.460
4itmATPTetraacyldisaccharide 4'-kinase/0.460
4tuvCPZCytochrome P450 1191.140.460
1ee9NADMethylenetetrahydrofolate dehydrogenase [NAD(+)]1.5.1.150.459
1h51FMNPentaerythritol tetranitrate reductase/0.459
1yb5NAPQuinone oxidoreductase1.6.5.50.459
2cy0NAPShikimate dehydrogenase (NADP(+))/0.459
2w6qOA5Biotin carboxylase6.3.4.140.459
4du82P0Mevalonate diphosphate decarboxylase/0.459
4eagATP5'-AMP-activated protein kinase subunit gamma-1/0.459
4xnw2IDP2Y purinoceptor 1/0.459
1icpFMN12-oxophytodienoate reductase 11.3.1.420.458
1z69F425,10-methylenetetrahydromethanopterin reductase/0.458
2fzwNADAlcohol dehydrogenase class-31.1.1.10.458
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.458
3bk2U5PRibonuclease J/0.458
3kjiADPCO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC/0.458
3kxw1ZZSaframycin Mx1 synthetase B/0.458
3v2uATPProtein GAL3/0.458
3zhbNAPPutative dehydrogenase/0.458
4bc7FADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.458
4m9aFDAAcyl-CoA dehydrogenase/0.458
4trnNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.458
5a3bAPRSIR2 family protein/0.458
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.458
5dt9NADErythronate-4-phosphate dehydrogenase/0.458
1bsvNDPGDP-L-fucose synthase/0.457
2aqiNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.457
2gnhH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.457
4cjx9L9C-1-tetrahydrofolate synthase, cytoplasmic, putative/0.457
4q0kGA3Phytohormone-binding protein/0.457
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.457
1ia1NDPDihydrofolate reductase1.5.1.30.456
2e9dB76Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.456
2g1r3IGRenin3.4.23.150.456
2q1uNADPutative nucleotide sugar epimerase/ dehydratase/0.456
2y8qADP5'-AMP-activated protein kinase subunit gamma-1/0.456
3d91REMRenin3.4.23.150.456
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.456
3gw9VNILanosterol 14-alpha-demethylase/0.456
3gwfNAPCyclohexanone monooxygenase/0.456
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.456
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.456
4eudCOASuccinyl-CoA:acetate CoA-transferase/0.456
4qxq1YEStimulator of interferon genes protein/0.456
4yaoFMNNADPH--cytochrome P450 reductase/0.456
1kl2FONSerine hydroxymethyltransferase/0.455
1rj6AZMCarbonic anhydrase 144.2.1.10.455
1zrzBI1Protein kinase C iota type2.7.11.130.455
2aqhNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.455
2ft9CHDFatty acid-binding protein 2, liver/0.455
3ekuCY9Actin-5C/0.455
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.455
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.455
4bb3KKAIsopenicillin N synthase1.21.3.10.455
4dptAGSMevalonate diphosphate decarboxylase/0.455
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.455
5cpbNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.455
5einNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.455
1cqp803Integrin alpha-L/0.454
1ddrMTXDihydrofolate reductase1.5.1.30.454
2d8aNADL-threonine 3-dehydrogenase/0.454
2v9jATP5'-AMP-activated protein kinase subunit gamma-1/0.454
3h3sH15Collagen type IV alpha-3-binding protein/0.454
3kb1ADPIron-sulfur cluster carrier protein/0.454
3nd1SAHPrecorrin-6A synthase (Deacetylating)/0.454
4jjiNADAlcohol dehydrogenase class-3/0.454
5hs1VORLanosterol 14-alpha demethylase/0.454
1dhrNADDihydropteridine reductase1.5.1.340.453
1i7gAZ2Peroxisome proliferator-activated receptor alpha/0.453
1rb3MTXDihydrofolate reductase1.5.1.30.453
1u1iNADMyo-inositol-1-phosphate synthase (Ino1)/0.453
2c27ACOMycothiol acetyltransferase2.3.1.1890.453
2fr0NDP6-deoxyerythronolide-B synthase EryA1, modules 1 and 2/0.453
2fzeAPRAlcohol dehydrogenase class-31.1.1.10.453
2g226IGRenin3.4.23.150.453
2j5xGSPADP-ribosylation factor 6/0.453
2npaMMBPeroxisome proliferator-activated receptor alpha/0.453
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.453
3qlsNDPDihydrofolate reductase1.5.1.30.453
3sptUD1Bifunctional protein GlmU/0.453
3w0nANPHygromycin-B 4-O-kinase2.7.1.1630.453
4bbyFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.453
4ccqFADThioredoxin reductase/0.453
4ei7GDPPlasmid replication protein RepX/0.453
4l9kEHFSerum albumin/0.453
4nd4NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.453
4uwmFMN3,6-diketocamphane 1,6 monooxygenase1.14.130.453
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.453
1bk0ACVIsopenicillin N synthase1.21.3.10.452
1t88CAMCamphor 5-monooxygenase1.14.15.10.452
2a92NAIL-lactate dehydrogenase/0.452
2ikuLIYRenin3.4.23.150.452
2ntjP1HEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.452
3b2eADPATPase GET3/0.452
3copADPGlycogen synthase2.4.1.210.452
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.452
3oadLPORenin3.4.23.150.452
4a862ANMajor pollen allergen Bet v 1-A/0.452
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.452
4g3jVNTLanosterol 14-alpha-demethylase/0.452
4g6gFADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.452
4hfr14MCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.452
4m83ERYOleandomycin glycosyltransferase2.4.10.452
4ryvZEAProtein LlR18A/0.452
1ib6NADMalate dehydrogenase/0.451
1icqFMN12-oxophytodienoate reductase 11.3.1.420.451
1jd0AZMCarbonic anhydrase 124.2.1.10.451
1nvtNAPShikimate dehydrogenase (NADP(+))/0.451
1o9bNAIQuinate/shikimate dehydrogenase/0.451
2b37NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.451
2ev9NAPShikimate dehydrogenase (NADP(+))/0.451
2z54AB1Gag-Pol polyprotein3.4.23.160.451
3u9eCOALmo1369 protein/0.451
4bcaFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.451
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.451
4q72FADBifunctional protein PutA/0.451
4zj8SUVOrexin receptor type 1/0.451
1fm4DXCMajor pollen allergen Bet v 1-L/0.450
1qlhNADAlcohol dehydrogenase E chain1.1.1.10.450
1uu9BI33-phosphoinositide-dependent protein kinase 12.7.11.10.450
2gevCOKPantothenate kinase2.7.1.330.450
2qo9ANPEphrin type-A receptor 32.7.10.10.450
2xiq5ADMethylmalonyl-CoA mutase, mitochondrial/0.450
3a1nNADNDP-sugar epimerase/0.450
3gkaFMNN-ethylmaleimide reductase/0.450
3oetNADErythronate-4-phosphate dehydrogenase/0.450
3p8jFMNPentaerythritol tetranitrate reductase/0.450
4a802ANMajor pollen allergen Bet v 1-A/0.450
4dquNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.450
4dreNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.450
4ipw1G7Mycocyclosin synthase1.14.21.90.450
4o1mNADEnoyl-acyl carrier reductase/0.450
4yaw2AMNADPH--cytochrome P450 reductase/0.450
4yr9NADL-threonine 3-dehydrogenase, mitochondrial1.1.1.1030.450
2aqkNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.449
2ghlLIBMitogen-activated protein kinase 14/0.449
2gjlFMNNitronate monooxygenase1.13.12.160.449
2i3gNAPN-acetyl-gamma-glutamyl-phosphate reductase1.2.1.380.449
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.449
2y4gTIRTamL/0.449
3mpt1GKMitogen-activated protein kinase 14/0.449
4b1rITCTetracycline repressor protein class D/0.449
4b8wNAPGDP-L-fucose synthase1.1.1.2710.449
4d0l093Phosphatidylinositol 4-kinase beta2.7.1.670.449
4dtiNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.449
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.449
4h3ySAHtRNA (guanine-N(1)-)-methyltransferase/0.449
4h6pFMNChromate reductase/0.449
1e5qNDPSaccharopine dehydrogenase [NADP(+), L-glutamate-forming]1.5.1.100.448
1hygNAPL-2-hydroxycarboxylate dehydrogenase (NAD(P)(+))/0.448
1i5bANPChemotaxis protein CheA2.7.13.30.448
1kbo340NAD(P)H dehydrogenase [quinone] 11.6.5.20.448
1kh3ANPArgininosuccinate synthase/0.448
1nuqNXXNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.448
1rftPXMPyridoxal kinase2.7.1.350.448
1x1aSAMC-20 methyltransferase/0.448
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.448
2fy4COACholine O-acetyltransferase2.3.1.60.448
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.448
2vtbFADCryptochrome DASH, chloroplastic/mitochondrial/0.448
3fskRO6Mitogen-activated protein kinase 14/0.448
3nxxNDPDihydrofolate reductase1.5.1.30.448
3zvmADPBifunctional polynucleotide phosphatase/kinase2.7.1.780.448
4b4vL34Bifunctional protein FolD/0.448
4bgiI4IEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.448
4r81FMNPredicted NADH dehydrogenase/0.448
1dxoFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.447
1f4fTP3Thymidylate synthase/0.447
1fxsNAPGDP-L-fucose synthase/0.447
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.447
1xs7MMIBeta-secretase 13.4.23.460.447
2d29FADAcyl-CoA dehydrogenase/0.447
2g1y5IGRenin3.4.23.150.447
2gstGPSGlutathione S-transferase Mu 12.5.1.180.447
2w6zL21Biotin carboxylase6.3.4.140.447
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.447
3fpjSAMUncharacterized protein/0.447
3hl0NADMaleylacetate reductase/0.447
3own3OXRenin3.4.23.150.447
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
4rlh0WEEnoyl-[acyl-carrier-protein] reductase [NADH]/0.447
5a3cNADSIR2 family protein/0.447
1a72PADAlcohol dehydrogenase E chain1.1.1.10.446
1f17NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.446
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.446
1owoFADDeoxyribodipyrimidine photo-lyase4.1.99.30.446
1rfuADPPyridoxal kinase2.7.1.350.446
2jn3JN3Fatty acid-binding protein, liver/0.446
2vbdV10Isopenicillin N synthase1.21.3.10.446
2yyeAPCSelenide, water dikinase2.7.9.30.446
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.446
3drcMTXDihydrofolate reductase1.5.1.30.446
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
3iocA5DPantothenate synthetase6.3.2.10.446
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
3oqfS51Renin3.4.23.150.446
3p8iFMNPentaerythritol tetranitrate reductase/0.446
3sz0FADSulfide-quinone reductase/0.446
4a6nFADTetX family tetracycline inactivation enzyme/0.446
4a84DXCMajor pollen allergen Bet v 1-A/0.446
4h8004TAldehyde dehydrogenase, dimeric NADP-preferring/0.446
4i13FOLDihydrofolate reductase1.5.1.30.446
4xguADPPutative pachytene checkpoint protein 2/0.446
1dr2TAPDihydrofolate reductase1.5.1.30.445
1icsFMN12-oxophytodienoate reductase 11.3.1.420.445
1q45FMN12-oxophytodienoate reductase 31.3.1.420.445
1rfvADPPyridoxal kinase2.7.1.350.445
1s64778Geranylgeranyl transferase type-1 subunit beta2.5.1.590.445
1t2cNAIL-lactate dehydrogenase1.1.1.270.445
1u3dFADCryptochrome-1/0.445
1vhzAPRADP compounds hydrolase NudE3.6.10.445
1yonA2R2-dehydropantoate 2-reductase1.1.1.1690.445
1zrqFAD5,10-methylenetetrahydrofolate reductase1.5.1.200.445
2aazCB3Thymidylate synthase2.1.1.450.445
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.445
2gv8NDPThiol-specific monooxygenase1.14.130.445
2i4qUA4Renin3.4.23.150.445
2p9gNAID-3-phosphoglycerate dehydrogenase1.1.1.950.445
2pzjNADPutative nucleotide sugar epimerase/ dehydratase/0.445
2qbmCAMCamphor 5-monooxygenase1.14.15.10.445
2znpK55Peroxisome proliferator-activated receptor delta/0.445
3ajrNADNDP-sugar epimerase/0.445
3hadNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.445
3i59N6RCRP-like cAMP-activated global transcriptional regulator/0.445
3iqiASN_GLU_ASN_ILECysteine synthase2.5.1.470.445
3muoZPRProlyl endopeptidase/0.445
3rukAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.445
3zuyTCHTransporter/0.445
4k8s1QTBeta-secretase 13.4.23.460.445
4xr9NADCalS8/0.445
1joaFADNADH peroxidase1.11.1.10.444
1zptFAD5,10-methylenetetrahydrofolate reductase1.5.1.200.444
2oapANPType II secretion system protein (GspE-2)/0.444
2po7CHDFerrochelatase, mitochondrial4.99.1.10.444
2zsaADPPantothenate kinase2.7.1.330.444
3gqvNAPEnoyl reductase LovC10.444
3of2NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
3p84FMNPentaerythritol tetranitrate reductase/0.444
3q43D66M1 family aminopeptidase3.4.110.444
3tnlNADShikimate dehydrogenase (NADP(+))/0.444
4dbzNDPPutative ketoacyl reductase1.3.10.444
4f1l0RYPoly [ADP-ribose] polymerase 142.4.2.300.444
4i1iNADMalate dehydrogenase/0.444
4k6fNAPPutative Acetoacetyl-CoA reductase/0.444
4ocpADPN-acetylhexosamine 1-kinase2.7.1.1620.444
1eupASD6-deoxyerythronolide B hydroxylase/0.443
1k6cMK1Gag-Pol polyprotein3.4.23.160.443
1nzfUPGDNA beta-glucosyltransferase/0.443
1o76CAMCamphor 5-monooxygenase1.14.15.10.443
1v35NAIEnoyl-ACP reductase/0.443
2b4rAESGlyceraldehyde-3-phosphate dehydrogenase/0.443
2bjfDXCCholoylglycine hydrolase3.5.1.240.443
2f1kNAPPrephenate dehydrogenase/0.443
2iko7IGRenin3.4.23.150.443
2uxpCLMHTH-type transcriptional regulator TtgR/0.443
2uxuNARHTH-type transcriptional regulator TtgR/0.443
2vtdLKMUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.443
2yxuATPPyridoxal kinase2.7.1.350.443
2zb3NDPProstaglandin reductase 21.3.1.480.443
2ztvNADD(-)-3-hydroxybutyrate dehydrogenase/0.443
3gstGPRGlutathione S-transferase Mu 12.5.1.180.443
4dldTZGGlutamate receptor ionotropic, kainate 1/0.443
4ead0NPThymidine phosphorylase2.4.2.40.443
4fi1ATPCasein kinase II subunit alpha2.7.11.10.443
4j1rI5RGlycogen synthase kinase-3 beta2.7.11.260.443
4jlj1NMDeoxycytidine kinase2.7.1.740.443
4mwhATPCasein kinase II subunit alpha2.7.11.10.443
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.443
4wecNADShort chain dehydrogenase/0.443
4xiwAZMCarbonic anhydrase, alpha type/0.443
5f8eSAHPossible transcriptional regulatory protein/0.443
1cf3FADGlucose oxidase1.1.3.40.442
1e3lNADAlcohol dehydrogenase 41.1.1.10.442
1hb3SCVIsopenicillin N synthase1.21.3.10.442
1ia3TQ5Dihydrofolate reductase1.5.1.30.442
1ib0NADNADH-cytochrome b5 reductase 31.6.2.20.442
1jolFFODihydrofolate reductase1.5.1.30.442
1kc1NDPdTDP-4-dehydrorhamnose reductase1.1.1.1330.442
1pr9NAPL-xylulose reductase1.1.1.100.442
1zp9ATPRIO-type serine/threonine-protein kinase Rio12.7.11.10.442
2dc1NADProbable L-aspartate dehydrogenase/0.442
2idkC2FGlycine N-methyltransferase2.1.1.200.442
2vkeTACTetracycline repressor protein class D/0.442
2x9dITCTetracycline repressor protein class D/0.442
2xc3RT8Steroid C26-monooxygenase1.14.13.1410.442
3c212BADNA integrity scanning protein DisA/0.442
3docNADGlyceraldehyde-3-phosphate dehydrogenase/0.442
3gobHXXDdmC/0.442
3omuIBDHeat shock protein 83/0.442
3qj4FADRenalase/0.442
3u8l09QAcetylcholine-binding protein/0.442
3uoyFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.442
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.442
4a8v2ANMajor pollen allergen Bet v 1-J/0.442
4a99FADTetX family tetracycline inactivation enzyme/0.442
4g6hNAIRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.442
4i231C9Epidermal growth factor receptor2.7.10.10.442
4k6mSAHGenome polyprotein/0.442
4qecNAPElxO/0.442
4qxmNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
4wriOKAOkadaic acid binding protein 2-alpha/0.442
4xfjANPArgininosuccinate synthase/0.442
4yagNAIC alpha-dehydrogenase/0.442
5adhAPRAlcohol dehydrogenase E chain1.1.1.10.442
1egeFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.441
1hb1OCVIsopenicillin N synthase1.21.3.10.441
1jioDEB6-deoxyerythronolide B hydroxylase/0.441
1l5s700Glycogen phosphorylase, liver form2.4.1.10.441
1mp0NADAlcohol dehydrogenase class-31.1.1.10.441
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.441
1udyFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.441
1w6hTITPlasmepsin-23.4.23.390.441
2a94AP0L-lactate dehydrogenase1.1.1.270.441
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
2dftADPShikimate kinase2.7.1.710.441
2o7oDXTTetracycline repressor protein class D/0.441
2rg6287Mitogen-activated protein kinase 14/0.441
3a1cACPProbable copper-exporting P-type ATPase A3.6.3.540.441
3a4vNADNDP-sugar epimerase/0.441
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.441
3etgNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.441
3i8p8403-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.441
4cf1IY7Integrase/0.441
4ihl1F514-3-3 protein zeta/delta/0.441
5czySAMEukaryotic huntingtin interacting protein B/0.441
5eaiFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.441
1ddsMTXDihydrofolate reductase1.5.1.30.440
1dxyNADD-2-hydroxyisocaproate dehydrogenase1.1.10.440
1svmATPLarge T antigen3.6.40.440
2fs4PZ1Renin3.4.23.150.440
2i40BLZCyclin-dependent kinase 22.7.11.220.440
2il2LIXRenin3.4.23.150.440
2iviACWIsopenicillin N synthase1.21.3.10.440
2iyfERYOleandomycin glycosyltransferase2.4.10.440
2x0iNAIMalate dehydrogenase/0.440
3dg8NDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.440
3gjwGJWPoly [ADP-ribose] polymerase 12.4.2.300.440
3junAKDPhenazine biosynthesis protein A/B/0.440
3mpjFADGlutaryl-CoA dehydrogenase1.3.99.320.440
3otbDGTProbable tRNA(His) guanylyltransferase2.7.7.790.440
3otxAP5Adenosine kinase, putative/0.440
3qlrNDPDihydrofolate reductase1.5.1.30.440
4eb5PLPCysteine desulfurase IscS 2/0.440
4ia7BIVVitamin D3 receptor A/0.440
4nieNBHNuclear receptor ROR-gamma/0.440
4oqyNDP(S)-imine reductase/0.440
4ure1PSCyclohexanol dehydrogenase/0.440
4zowCLMMultidrug transporter MdfA/0.440
5eioNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.440
5eoxADPType 4 fimbrial biogenesis protein PilM/0.440
5jlaNADPutative short-chain dehydrogenase/reductase/0.440