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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2iehMOYKinesin-like protein KIF11

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
2iehMOYKinesin-like protein KIF11/1.000
1q0bNATKinesin-like protein KIF11/0.696
4bbgV02Kinesin-like protein KIF11/0.636
2g1qN9HKinesin-like protein KIF11/0.625
2x7dEGBKinesin-like protein KIF11/0.625
3k5eK5EKinesin-like protein KIF11/0.623
2x7cKZ9Kinesin-like protein KIF11/0.618
1x88NATKinesin-like protein KIF11/0.617
2x7eX7EKinesin-like protein KIF11/0.617
2xae2XAKinesin-like protein KIF11/0.615
3kenZZDKinesin-like protein KIF11/0.612
3k3bL31Kinesin-like protein KIF11/0.604
2q2zMKKKinesin-like protein KIF11/0.597
2gm12AZKinesin-like protein KIF11/0.596
2x2rX2OKinesin-like protein KIF11/0.596
2wogZZDKinesin-like protein KIF11/0.594
2fme3QCKinesin-like protein KIF11/0.588
4a51DQ8Kinesin-like protein KIF11/0.559
4as76LXKinesin-like protein KIF11/0.515
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.501
4l4fCAMCamphor 5-monooxygenase1.14.15.10.495
2a1mCAMCamphor 5-monooxygenase1.14.15.10.494
1hfqMOTDihydrofolate reductase1.5.1.30.493
3l63CAMCamphor 5-monooxygenase1.14.15.10.493
4a5yG7XKinesin-like protein KIF11/0.492
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.491
3nmpPYVAbscisic acid receptor PYL2/0.489
4yswNAIXanthine dehydrogenase/oxidase/0.489
4z34ON7Lysophosphatidic acid receptor 1/0.486
2uxuNARHTH-type transcriptional regulator TtgR/0.482
3lfnA27Cyclin-dependent kinase 22.7.11.220.481
3gwfNAPCyclohexanone monooxygenase/0.480
1sm2STUTyrosine-protein kinase ITK/TSK2.7.10.20.478
3nuuJOZ3-phosphoinositide-dependent protein kinase 12.7.11.10.478
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.477
2uxpCLMHTH-type transcriptional regulator TtgR/0.477
2vd5BI8Myotonin-protein kinase2.7.11.10.477
4enhFVXCholesterol 24-hydroxylase/0.477
1h1pCMGCyclin-dependent kinase 22.7.11.220.476
2bxe1FLSerum albumin/0.476
1dz8CAMCamphor 5-monooxygenase1.14.15.10.475
1h1r6CPCyclin-dependent kinase 22.7.11.220.475
3uic09TEnoyl-[acyl-carrier-protein] reductase [NADH]/0.475
4nmbFADBifunctional protein PutA/0.475
1t85CAMCamphor 5-monooxygenase1.14.15.10.474
4erwSTUCyclin-dependent kinase 22.7.11.220.474
4mcc21XtRNA (guanine-N(1)-)-methyltransferase2.1.1.2280.474
1e1nFADNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.473
3drcMTXDihydrofolate reductase1.5.1.30.473
1o76CAMCamphor 5-monooxygenase1.14.15.10.472
2e0aANP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial2.7.11.20.472
3w0gW07Vitamin D3 receptor/0.472
4cztCPSCBL-interacting serine/threonine-protein kinase 232.7.11.10.472
4iyg1HUStrictosidine synthase4.3.3.20.472
4egnTWOCytochrome P450/0.471
4l2iFADElectron transfer flavoprotein alpha/beta-subunit/0.471
4l4eCAMCamphor 5-monooxygenase1.14.15.10.471
3d0bSNXHeat shock protein HSP 90-alpha/0.470
3sa9A68Protease/0.470
1oguST8Cyclin-dependent kinase 22.7.11.220.469
1tj0FADBifunctional protein PutA1.5.5.20.469
4an35Y0Dual specificity mitogen-activated protein kinase kinase 12.7.12.20.469
4asg814ATP-dependent molecular chaperone HSP82/0.469
4djoMK5Pol polyprotein/0.469
2nnlNAPDihydroflavonol 4-reductase1.1.1.2190.468
3a783EVVitamin D3 receptor/0.468
3aidARQGag-Pol polyprotein3.4.23.160.468
3ddqRRCCyclin-dependent kinase 22.7.11.220.468
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.468
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.468
4fad0TBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.468
4fsmHK1Serine/threonine-protein kinase Chk12.7.11.10.468
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.468
4i13FOLDihydrofolate reductase1.5.1.30.468
5hs1VORLanosterol 14-alpha demethylase/0.468
1aq1STUCyclin-dependent kinase 22.7.11.220.467
1e8wQUEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.467
1f20FADNitric oxide synthase, brain1.14.13.390.467
4asf62UATP-dependent molecular chaperone HSP82/0.467
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.466
2jlaTPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.466
2qbmCAMCamphor 5-monooxygenase1.14.15.10.466
2xjjL81Heat shock protein HSP 90-alpha/0.466
3fwgCAMCamphor 5-monooxygenase1.14.15.10.466
3gi4K60Gag-Pol polyprotein/0.466
3ukuC69Actin-related protein 3/0.466
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.466
1ove358Mitogen-activated protein kinase 14/0.465
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.465
2itpAEEEpidermal growth factor receptor2.7.10.10.465
2w05FRTCyclin-dependent kinase 22.7.11.220.465
3b9lAZZSerum albumin/0.465
3cppCAMCamphor 5-monooxygenase1.14.15.10.465
4g48PZBMycocyclosin synthase1.14.21.90.465
1fm69CRRetinoic acid receptor RXR-alpha/0.464
1z1hHBBGag-Pol polyprotein3.4.23.160.464
2c29NAPDihydroflavonol 4-reductase/0.464
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.464
3sa755AProtease/0.464
3wrjCAMCamphor 5-monooxygenase1.14.15.10.464
4nm9FADBifunctional protein PutA/0.464
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.463
2zbaZBATrichothecene 3-O-acetyltransferase/0.463
3qx4X4BCyclin-dependent kinase 22.7.11.220.463
3u9eCOALmo1369 protein/0.463
4y8wSTRSteroid 21-hydroxylase/0.463
1dz6CAMCamphor 5-monooxygenase1.14.15.10.462
1ne6SP1cAMP-dependent protein kinase type I-alpha regulatory subunit/0.462
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.462
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.462
2x1nX1NCyclin-dependent kinase 22.7.11.220.462
3hazFADBifunctional protein PutA/0.462
3oafOAGDihydrofolate reductase1.5.1.30.462
3s1dZIRCytokinin dehydrogenase 11.5.99.120.462
4eor4SPCyclin-dependent kinase 22.7.11.220.462
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.462
4hvh19RTyrosine-protein kinase JAK32.7.10.20.462
4njt017Protease/0.462
1df7MTXDihydrofolate reductase1.5.1.30.461
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.461
1phePIYCamphor 5-monooxygenase1.14.15.10.461
2avvMK1Gag-Pol polyprotein3.4.23.160.461
2yexYEXSerine/threonine-protein kinase Chk12.7.11.10.461
2zcePYLPyrrolysine--tRNA ligase/0.461
3gi3B10Mitogen-activated protein kinase 14/0.461
3lqfNADGalactitol dehydrogenase/0.461
3r8pZ46Cyclin-dependent kinase 22.7.11.220.461
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.461
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.460
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.460
2cchATPCyclin-dependent kinase 22.7.11.220.460
2ejzSAHDiphthine synthase/0.460
2jb4A14Isopenicillin N synthase1.21.3.10.460
2w3aTOPDihydrofolate reductase1.5.1.30.460
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.460
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.460
3qqlX03Cyclin-dependent kinase 22.7.11.220.460
3vfa031Gag-Pol polyprotein3.4.23.160.460
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.460
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.460
4kkyCAMCamphor 5-monooxygenase1.14.15.10.460
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.460
4z35ON9Lysophosphatidic acid receptor 1/0.460
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.459
1t86CAMCamphor 5-monooxygenase1.14.15.10.459
2pziAXXSerine/threonine-protein kinase PknG2.7.11.10.459
3hadNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.459
3ozc4CTS-methyl-5'-thioadenosine phosphorylase/0.459
4dcmSAMRibosomal RNA large subunit methyltransferase G2.1.1.1740.459
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.459
4nj32KDCyclin-dependent kinase 22.7.11.220.459
5aacVGHALK tyrosine kinase receptor2.7.10.10.459
5dqrFAD7-hydroxymethyl chlorophyll a reductase, chloroplastic1.17.7.20.459
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.458
1yrdCAMCamphor 5-monooxygenase1.14.15.10.458
3b2sB2STrichothecene 3-O-acetyltransferase/0.458
3el1DR7Gag-Pol polyprotein3.4.23.160.458
3fwiCAMCamphor 5-monooxygenase1.14.15.10.458
3ixp834Ecdysone receptor/0.458
3kdiA8SAbscisic acid receptor PYL2/0.458
3qn8NI7Gag-Pol polyprotein3.4.23.160.458
3t3q9PLCytochrome P450 2A61.14.130.458
4ei7GDPPlasmid replication protein RepX/0.458
1hk4T44Serum albumin/0.457
1hvlA76Gag-Pol polyprotein/0.457
1iwiCAMCamphor 5-monooxygenase1.14.15.10.457
1oirHDYCyclin-dependent kinase 22.7.11.220.457
1rekB8LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.457
2a87FADThioredoxin reductase1.8.1.90.457
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.457
2m56CAMCamphor 5-monooxygenase1.14.15.10.457
2pmdGNPTranslation initiation factor 2 subunit gamma/0.457
2uxhQUEHTH-type transcriptional regulator TtgR/0.457
2vw5BC6ATP-dependent molecular chaperone HSP82/0.457
3fwjCAMCamphor 5-monooxygenase1.14.15.10.457
3otbDGTProbable tRNA(His) guanylyltransferase2.7.7.790.457
4ek1CAMCamphor 5-monooxygenase1.14.15.10.457
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
1dz4CAMCamphor 5-monooxygenase1.14.15.10.456
1f8sFADL-amino-acid oxidase1.4.3.20.456
1fmjRTLRetinol dehydratase/0.456
1kl2FONSerine hydroxymethyltransferase/0.456
1oiuN76Cyclin-dependent kinase 22.7.11.220.456
2uztSS3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.456
2vn0TDZCytochrome P450 2C8/0.456
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.456
3ec0GRLGag-Pol polyprotein3.4.23.470.456
3ibqATPPyridoxal kinase/0.456
3jvy017Gag-Pol polyprotein3.4.23.160.456
3ujlA8SAbscisic acid receptor PYL2/0.456
4xdmGDMHeat shock cognate 90 kDa protein/0.456
5aabVGHALK tyrosine kinase receptor2.7.10.10.456
1bygSTUTyrosine-protein kinase CSK/0.455
1jhrP2PNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.455
1q1rFADPutidaredoxin reductase1.18.1.50.455
1uu8BI13-phosphoinositide-dependent protein kinase 12.7.11.10.455
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.455
2fdd385Pol protein/0.455
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.455
2vtlLZ5Cyclin-dependent kinase 22.7.11.220.455
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.455
3p2eSAH16S rRNA (adenine(1408)-N(1))-methyltransferase2.1.1.1800.455
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.455
4hnc0UTMandelate racemase/0.455
4jazSTLPeroxisome proliferator-activated receptor gamma/0.455
4l4bCAMCamphor 5-monooxygenase1.14.15.10.455
4la7A1OAbscisic acid receptor PYL2/0.455
4tzk641Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.455
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.455
5dg3U21Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase/0.455
6cp4CAMCamphor 5-monooxygenase1.14.15.10.455
1jhaAAMNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.454
1snuSTUTyrosine-protein kinase ITK/TSK2.7.10.20.454
1xl2189Gag-Pol polyprotein3.4.23.160.454
2aidTHKGag-Pol polyprotein3.4.23.160.454
2breKJ2ATP-dependent molecular chaperone HSP82/0.454
2hog710Serine/threonine-protein kinase Chk12.7.11.10.454
2q7vFADThioredoxin reductase/0.454
2qbnCAMCamphor 5-monooxygenase1.14.15.10.454
3a8wATPProtein kinase C iota type2.7.11.130.454
3em6017Gag-Pol polyprotein3.4.23.160.454
3gobHXXDdmC/0.454
3negPYVAbscisic acid receptor PYL1/0.454
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.454
4g95OAGDihydrofolate reductase1.5.1.30.454
4l4aCAMCamphor 5-monooxygenase1.14.15.10.454
4l4dCAMCamphor 5-monooxygenase1.14.15.10.454
5e8wSTUTGF-beta receptor type-12.7.11.300.454
1npvL27Gag-Pol polyprotein3.4.23.160.453
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.453
1t87CAMCamphor 5-monooxygenase1.14.15.10.453
2cduFADNADH oxidase/0.453
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.453
2ds11CDCyclin-dependent kinase 22.7.11.220.453
2itwITQEpidermal growth factor receptor2.7.10.10.453
2qblCAMCamphor 5-monooxygenase1.14.15.10.453
3au8NDP1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic1.1.1.2670.453
3mvl38PMitogen-activated protein kinase 14/0.453
3tk3CPZCytochrome P450 2B41.14.14.10.453
3u2lFADFAD-linked sulfhydryl oxidase ALR1.8.3.20.453
4cp4CAMCamphor 5-monooxygenase1.14.15.10.453
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.453
4g3rCAMCamphor 5-monooxygenase1.14.15.10.453
4gk4L90Ephrin type-A receptor 32.7.10.10.453
4h4uNDPBiphenyl dioxygenase ferredoxin reductase subunit/0.453
4lgaA2OAbscisic acid receptor PYL2/0.453
4njvRITProtease/0.453
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.453
4xgxADPFAD:protein FMN transferase/0.453
4yryFADGlutamate synthase, beta subunit/0.453
1ay0TPPTransketolase 12.2.1.10.452
1bpjUMPThymidylate synthase/0.452
1cjuFOKAdenylate cyclase type 2/0.452
1cjuFOKAdenylate cyclase type 5/0.452
1ec3MS3Gag-Pol polyprotein3.4.23.160.452
1nooCAHCamphor 5-monooxygenase1.14.15.10.452
1oqcFADFAD-linked sulfhydryl oxidase ALR1.8.3.20.452
1ouk084Mitogen-activated protein kinase 14/0.452
2qi5MZ7Gag-Pol polyprotein/0.452
2uxoTACHTH-type transcriptional regulator TtgR/0.452
2zawCAMCamphor 5-monooxygenase1.14.15.10.452
3ekyDR7Gag-Pol polyprotein3.4.23.160.452
3el9DR7Gag-Pol polyprotein3.4.23.160.452
3gi5K62Gag-Pol polyprotein/0.452
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.452
3lxiCAMCytochrome P450/0.452
3mdmFJZCholesterol 24-hydroxylase/0.452
3nd1SAHPrecorrin-6A synthase (Deacetylating)/0.452
3orn3ORDual specificity mitogen-activated protein kinase kinase 12.7.12.20.452
3pl8FADPyranose 2-oxidase/0.452
3uleC69Actin-related protein 3/0.452
3zoiM2WIsopenicillin N synthase1.21.3.10.452
3zvuA8SAbscisic acid receptor PYR1/0.452
4asjN6AGlucose-1-phosphate thymidylyltransferase/0.452
4c9oCAMCytochrome P450/0.452
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.452
4lg5A1OAbscisic acid receptor PYL2/0.452
1d4yTPVGag-Pol polyprotein3.4.23.160.451
1e8zSTUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
1mtrPI6Gag-Pol polyprotein3.4.23.160.451
1w06W05Isopenicillin N synthase1.21.3.10.451
2ibzUQ6Cytochrome b/0.451
2idw017Protease/0.451
2ij7TPFMycocyclosin synthase1.14.21.90.451
2iwsNP4ATP-dependent molecular chaperone HSP82/0.451
2j9fTHV2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial1.2.4.40.451
2j9fTHV2-oxoisovalerate dehydrogenase subunit beta, mitochondrial1.2.4.40.451
2np8CC3Aurora kinase A2.7.11.10.451
2rl52RLVascular endothelial growth factor receptor 22.7.10.10.451
2wmsZYSSerine/threonine-protein kinase Chk12.7.11.10.451
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.451
3g49NAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.451
3ox1695Ribosyldihydronicotinamide dehydrogenase [quinone]/0.451
3pwrROCGag-Pol polyprotein3.4.23.160.451
3qp0NI8Gag-Pol polyprotein3.4.23.160.451
3qrtX14Cyclin-dependent kinase 22.7.11.220.451
3rjc06ZCyclin-dependent kinase 22.7.11.220.451
4ap1NAPSteroid monooxygenase/0.451
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.451
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.451
4h3ySAHtRNA (guanine-N(1)-)-methyltransferase/0.451
4hhdFMNPhototropin-12.7.11.10.451
4n49MGTCap-specific mRNA (nucleoside-2'-O-)-methyltransferase 12.1.1.570.451
5c8yACPTubulin tyrosine ligase/0.451
5cp4CAMCamphor 5-monooxygenase1.14.15.10.451
1bwlFMNNADPH dehydrogenase 11.6.99.10.450
1ke6LS2Cyclin-dependent kinase 22.7.11.220.450
1pg3PRXAcetyl-coenzyme A synthetase/0.450
1sduMK1Gag-Pol polyprotein3.4.23.160.450
1t88CAMCamphor 5-monooxygenase1.14.15.10.450
1z1rHBHGag-Pol polyprotein3.4.23.160.450
2i4wKGQProtease/0.450
2j0k4STFocal adhesion kinase 12.7.10.20.450
2qboCAMCamphor 5-monooxygenase1.14.15.10.450
2vtbFADCryptochrome DASH, chloroplastic/mitochondrial/0.450
2yfxVGHALK tyrosine kinase receptor2.7.10.10.450
2zaxCAMCamphor 5-monooxygenase1.14.15.10.450
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.450
3afhGSUGlutamate--tRNA ligase 2/0.450
3d20017Gag-Pol polyprotein3.4.23.160.450
3lfqA28Cyclin-dependent kinase 22.7.11.220.450
3mvm39PMitogen-activated protein kinase 14/0.450
3wrmCAMCamphor 5-monooxygenase1.14.15.10.450
3wv9FEGHmd co-occurring protein HcgE/0.450
4er6AW2Histone-lysine N-methyltransferase, H3 lysine-79 specific2.1.1.430.450
4ftaH5KSerine/threonine-protein kinase Chk12.7.11.10.450
4zj8SUVOrexin receptor type 1/0.450
1bwsNDPGDP-L-fucose synthase/0.449
1dw60Q4Gag-Pol polyprotein3.4.23.160.449
1fm4DXCMajor pollen allergen Bet v 1-L/0.449
1gjvAGS[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial2.7.11.40.449
1hk5T44Serum albumin/0.449
1l4mNCNNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.449
1os1ATPPhosphoenolpyruvate carboxykinase (ATP)/0.449
1v0oINRCell division control protein 2 homolog2.7.11.220.449
2pulACPMethylthioribose kinase2.7.1.1000.449
2uxzHI1Gag-Pol polyprotein3.4.23.160.449
2xa4AZ5Tyrosine-protein kinase JAK2/0.449
2yj5ATPCopper-transporting ATPase/0.449
3dgaRJ1Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.449
3ekv478Gag-Pol polyprotein3.4.23.160.449
3nup3NUCyclin-dependent kinase 62.7.11.220.449
3r8lZ30Cyclin-dependent kinase 22.7.11.220.449
3rpr25ZCyclin-dependent kinase 22.7.11.220.449
3wrlCAMCamphor 5-monooxygenase1.14.15.10.449
3wsjMK1Protease/0.449
3zpuM8BGag-Pol polyprotein3.4.23.160.449
4b2wBZ0Glucose-1-phosphate thymidylyltransferase/0.449
4c9pCAMCytochrome P450/0.449
4dqb017Gag-Pol polyprotein/0.449
4ds8A8SAbscisic acid receptor PYL3/0.449
4fkpLS5Cyclin-dependent kinase 22.7.11.220.449
4ivd15TTyrosine-protein kinase JAK1/0.449
1idb0DOGag-Pol polyprotein/0.448
1izhQ50Protease/0.448
1sdtMK1Gag-Pol polyprotein3.4.23.160.448
1zys199Serine/threonine-protein kinase Chk12.7.11.10.448
2bbqPFGThymidylate synthase/0.448
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.448
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.448
2iw84SPCyclin-dependent kinase 22.7.11.220.448
2p1t3TNRetinoic acid receptor RXR-alpha/0.448
2rh9IGPTryptophan synthase alpha chain/0.448
2upjU02Gag-Pol polyprotein3.4.23.160.448
2wo7ASVIsopenicillin N synthase1.21.3.10.448
2ykcYKCHeat shock protein HSP 90-alpha/0.448
3flsFLSMitogen-activated protein kinase 14/0.448
3fp0FP015-O-acetyltransferase/0.448
3fr8NDPKetol-acid reductoisomerase, chloroplastic1.1.1.860.448
3fu9KIBLaccase-11.10.3.20.448
3ggxGGXGag-Pol polyprotein/0.448
3hx4ANPCalmodulin-domain protein kinase 1/0.448
3lxdFADFAD-dependent pyridine nucleotide-disulfide oxidoreductase/0.448
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.448
3nxe2NCProtease/0.448
3o9iA61Gag-Pol polyprotein/0.448
3uwqU5POrotidine 5'-phosphate decarboxylase/0.448
4apuA2KProgesterone receptor/0.448
4ihl1F514-3-3 protein zeta/delta/0.448
4oacADPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.448
5c8wPCGcGMP-dependent protein kinase 22.7.11.120.448
5ca0ACPTubulin tyrosine ligase/0.448
1bv7XV6Gag-Pol polyprotein3.4.23.160.447
1fl2FADAlkyl hydroperoxide reductase subunit F1.8.10.447
1h1s4SPCyclin-dependent kinase 22.7.11.220.447
1metDMPGag-Pol polyprotein3.4.23.160.447
1pxlCK4Cyclin-dependent kinase 22.7.11.220.447
1xdiFADNAD(P)H dehydrogenase (quinone)/0.447
2hs2017Protease/0.447
2ic3HBYGag-Pol polyprotein2.7.7.490.447
2iwuNP5ATP-dependent molecular chaperone HSP82/0.447
2pmnK51Protein kinase 7/0.447
2qd7065Gag-Pol polyprotein3.4.23.160.447
2qhcAB1Protease/0.447
2yy8MTAtRNA (cytidine(56)-2'-O)-methyltransferase/0.447
3fwfCAMCamphor 5-monooxygenase1.14.15.10.447
3h3cP1EProtein-tyrosine kinase 2-beta2.7.10.20.447
3ntaFADFAD-dependent pyridine nucleotide-disulphide oxidoreductase/0.447
3r1sX73Cyclin-dependent kinase 22.7.11.220.447
3t113T1Gag-Pol polyprotein3.4.23.160.447
3t3c017Gag-Pol polyprotein3.4.23.160.447
3uxe465Ribosyldihydronicotinamide dehydrogenase [quinone]/0.447
3vt7VDXVitamin D3 receptor/0.447
4ansVGHALK tyrosine kinase receptor2.7.10.10.447
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.447
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.447
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.447
4ho6UTPGlucose-1-phosphate thymidylyltransferase/0.447
4hyp1A1DNA gyrase subunit B/0.447
4kshHTTDNA gyrase subunit B/0.447
4ktkKTKCytochrome P450/0.447
4l4cCAMCamphor 5-monooxygenase1.14.15.10.447
4n3b12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.447
4o0sADNAurora kinase A2.7.11.10.447
4u03GTPCyclic GMP-AMP synthase/0.447
1d4jMSCGag-Pol polyprotein3.4.23.160.446
1dhrNADDihydropteridine reductase1.5.1.340.446
1ebwBEIGag-Pol polyprotein3.4.23.160.446
1eioGCHGastrotropin/0.446
1hsgMK1Gag-Pol polyprotein/0.446
1ida0POGag-Pol polyprotein3.4.23.470.446
1oi9N20Cyclin-dependent kinase 22.7.11.220.446
1uu9BI33-phosphoinositide-dependent protein kinase 12.7.11.10.446
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.446
2chw039Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
2gpuOHTEstrogen-related receptor gamma/0.446
2i4vDJRV-1 protease/0.446
2qi3MZ5Gag-Pol polyprotein/0.446
2qi4MZ6Gag-Pol polyprotein/0.446
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.446
2vwcBC2ATP-dependent molecular chaperone HSP82/0.446
2wi1ZZ2Heat shock protein HSP 90-alpha/0.446
3gi6D78Gag-Pol polyprotein/0.446
3kdjA8SAbscisic acid receptor PYL1/0.446
3nefPYVAbscisic acid receptor PYL1/0.446
3nwq2NCGag-Pol polyprotein3.4.23.160.446
3opdHIEHeat shock protein 83/0.446
3tbaADPRibonucleoside-diphosphate reductase large chain 11.17.4.10.446
3zewSTUEphrin type-B receptor 42.7.10.10.446
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
4nkvAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.446
4xuhSFIPeroxisome proliferator-activated receptor gamma/0.446
4ej4EJ4Delta-type opioid receptor/0.446
1a9mU0EGag-Pol polyprotein/0.445
1b39ATPCyclin-dependent kinase 22.7.11.220.445
1d4kPI8Gag-Pol polyprotein3.4.23.160.445
1difA85Gag-Pol polyprotein/0.445
1fdwESTEstradiol 17-beta-dehydrogenase 11.1.1.620.445
1l5k1RBNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.445
1nzfUPGDNA beta-glucosyltransferase/0.445
1oitHDTCyclin-dependent kinase 22.7.11.220.445
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.445
1uu7BI23-phosphoinositide-dependent protein kinase 12.7.11.10.445
2bpv1INGag-Pol polyprotein3.4.23.160.445
2bpxMK1Gag-Pol polyprotein3.4.23.160.445
2btsU32Cyclin-dependent kinase 22.7.11.220.445
2c5yMTWCyclin-dependent kinase 22.7.11.220.445
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.445
2feuCAMCamphor 5-monooxygenase1.14.15.10.445
2oj9BMIInsulin-like growth factor 1 receptor2.7.10.10.445
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.445
2wepADPATP-dependent molecular chaperone HSP82/0.445
2y60M8FIsopenicillin N synthase1.21.3.10.445
2zkjADP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial2.7.11.20.445
3a2oKNJGag-Pol polyprotein3.4.23.160.445
3a4pDFQHepatocyte growth factor receptor2.7.10.10.445
3c11GDMATP-dependent molecular chaperone HSP82/0.445
3cktYDPGag-Pol polyprotein3.4.23.160.445
3kljFADNADH-rubredoxin oxidoreductase1.18.1.10.445
3nnxEDDMitogen-activated protein kinase 14/0.445
3r73X87Cyclin-dependent kinase 22.7.11.220.445
3st5G89Gag-Pol polyprotein3.4.23.160.445
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.445
3vtdTKDVitamin D3 receptor/0.445
4b99R4LMitogen-activated protein kinase 72.7.11.240.445
4brdANPEctonucleoside triphosphate diphosphohydrolase I/0.445
4jdaA9SAbscisic acid receptor PYL3/0.445
5dr9SKEAurora kinase A2.7.11.10.445
1byqADPHeat shock protein HSP 90-alpha/0.444
1cjtFOKAdenylate cyclase type 2/0.444
1cjtFOKAdenylate cyclase type 5/0.444
1ee9NADMethylenetetrahydrofolate dehydrogenase [NAD(+)]1.5.1.150.444
1o9bNAIQuinate/shikimate dehydrogenase/0.444
1v0pPVBCell division control protein 2 homolog2.7.11.220.444
2a1oCAMCamphor 5-monooxygenase1.14.15.10.444
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.444
2cppCAMCamphor 5-monooxygenase1.14.15.10.444
2fde385Gag-Pol polyprotein3.4.23.160.444
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.444
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.444
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.444
3cseN22Uncharacterized protein/0.444
3em4DR7Gag-Pol polyprotein3.4.23.160.444
3f46I2C5,10-methenyltetrahydromethanopterin hydrogenase1.12.98.20.444
3ndcSAHPrecorrin-4 C(11)-methyltransferase2.1.1.1330.444
3ntdFADFAD-dependent pyridine nucleotide-disulphide oxidoreductase/0.444
3pj8404Cyclin-dependent kinase 22.7.11.220.444
3qroNK9Gag-Pol polyprotein3.4.23.160.444
3rk708ZCyclin-dependent kinase 22.7.11.220.444
3t3r9PLCytochrome P450 2A61.14.130.444
3t7x4SHEndothiapepsin3.4.23.220.444
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.444
4cdmFADDeoxyribodipyrimidine photolyase/0.444
4ek610KCyclin-dependent kinase 22.7.11.220.444
4jbqVX6Aurora kinase A2.7.11.10.444
4jlj1NMDeoxycytidine kinase2.7.1.740.444
4n6hEJ4Delta-type opioid receptor/0.444
1dajMOTDihydrofolate reductase1.5.1.30.443
1dnpFADDeoxyribodipyrimidine photo-lyase4.1.99.30.443
1gebCAMCamphor 5-monooxygenase1.14.15.10.443
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.443
1lfdGNPGTPase HRas/0.443
1ohr1UNV-1 PROTEASE protein/0.443
1p1bSAHGuanidinoacetate N-methyltransferase2.1.1.20.443
1vi2NADQuinate/shikimate dehydrogenase/0.443
2a1nCAMCamphor 5-monooxygenase1.14.15.10.443
2b9fADPMitogen-activated protein kinase FUS32.7.11.240.443
2bpy3INGag-Pol polyprotein3.4.23.160.443
2bw7ECSAdenylate cyclase/0.443
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.443
2e08SAHDiphthine synthase/0.443
2f3kRO1Protease/0.443
2gr1FADFerredoxin reductase/0.443
2i40BLZCyclin-dependent kinase 22.7.11.220.443
2iorADPChaperone protein HtpG/0.443
2q0kFADThioredoxin reductase1.8.1.90.443
2q9fC3SCholesterol 24-hydroxylase/0.443
2qnqQN3Gag-Pol polyprotein3.4.23.160.443
2r5pMK1Gag-Pol polyprotein/0.443
2yekEAMBromodomain-containing protein 2/0.443
2z97CAMCamphor 5-monooxygenase1.14.15.10.443
2zva1N1Tyrosine-protein kinase Lyn2.7.10.20.443
3fl4FL4Mitogen-activated protein kinase 14/0.443
3flzFLZMitogen-activated protein kinase 14/0.443
3i7eDJRGag-Pol polyprotein/0.443
3lfm3DTAlpha-ketoglutarate-dependent dioxygenase FTO/0.443
3lkhLT6Genome polyprotein2.7.7.480.443
3n0tOPYDipeptidyl peptidase 23.4.14.20.443
3njoP2MAbscisic acid receptor PYR1/0.443
3ojiPYVAbscisic acid receptor PYL3/0.443
3oxxDR7Gag-Pol polyprotein3.4.23.160.443
3p67FMNPentaerythritol tetranitrate reductase/0.443
3qu0X40Cyclin-dependent kinase 22.7.11.220.443
3sa323XProtease/0.443
3t10ACPHeat shock protein HSP 90-alpha/0.443
4ce3L4VATP-dependent molecular chaperone HSP82/0.443
4f09JAKTyrosine-protein kinase JAK2/0.443
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.443
4hdpG52Gag-Pol polyprotein3.4.23.160.443
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.443
4u0k744Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
4xj43ATCyclic GMP-AMP synthase/0.443
1a27ESTEstradiol 17-beta-dehydrogenase 11.1.1.620.442
1b6pPI7Gag-Pol polyprotein3.4.23.160.442
1bdqIM1Gag-Pol polyprotein3.4.23.160.442
1dirNADDihydropteridine reductase1.5.1.340.442
1fff0Q4Gag-Pol polyprotein3.4.23.160.442
1fmlRTLRetinol dehydratase/0.442
1hbvGANGag-Pol polyprotein/0.442
1k2c0Q4Gag-Pol polyprotein3.4.23.160.442
1qbsDMPGag-Pol polyprotein3.4.23.160.442
1sbgIM1Gag-Pol polyprotein/0.442
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.442
1w0kADPATP synthase subunit alpha, mitochondrial/0.442
1w0kADPATP synthase subunit beta, mitochondrial3.6.3.140.442
2azzTCHPhospholipase A2, major isoenzyme3.1.1.40.442
2b0qADPAminoglycoside 3'-phosphotransferase2.7.1.950.442
2f80017Gag-Pol polyprotein3.4.23.160.442
2gjlFMNNitronate monooxygenase1.13.12.160.442
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.442
2izuP01Casein kinase I isoform gamma-32.7.11.10.442
2j5xGSPADP-ribosylation factor 6/0.442
2p3a3TLPol protein/0.442
2rkfAB1Pol protein/0.442
2uzbC75Cyclin-dependent kinase 22.7.11.220.442
2yee2ECHeat shock protein HSP 90-alpha/0.442
3anxMTAPolyamine aminopropyltransferase/0.442
3clbTMQBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.442
3dolGWIPol protein/0.442
3kf03TLGag-Pol polyprotein/0.442
3lfsA07Cyclin-dependent kinase 22.7.11.220.442
3od0PCGcGMP-dependent protein kinase 12.7.11.120.442
3oy4017Gag-Pol polyprotein3.4.23.160.442
3s0o50ZCyclin-dependent kinase 22.7.11.220.442
4as94QSATP-dependent molecular chaperone HSP82/0.442
4djqM86Pol polyprotein/0.442
4ivb1J5Tyrosine-protein kinase JAK1/0.442
4oicA8SBet v I allergen-like/0.442
4q1x017Gag-Pol polyprotein3.4.23.160.442
1bdrIM1Gag-Pol polyprotein3.4.23.160.441
1g35AHFGag-Pol polyprotein3.4.23.160.441
1mc1PCXCarboxyethyl-arginine beta-lactam-synthase6.3.3.40.441
1mrwK57Gag-Pol polyprotein3.4.23.160.441
1phhFADp-hydroxybenzoate hydroxylase/0.441
1pkdUCNCyclin-dependent kinase 22.7.11.220.441
1rx5DDFDihydrofolate reductase1.5.1.30.441
1sh9RITGag-Pol polyprotein3.4.23.160.441
1sivPSIGag-Pol polyprotein/0.441
1tcxIM1Gag-Pol polyprotein3.4.23.160.441
1upcTPPN(2)-(2-carboxyethyl)arginine synthase/0.441
1ybuAPCProbable lignin peroxidase LipJ/0.441
2exlGDMEndoplasmin/0.441
2nnpROCProtease/0.441
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.441
2q59240Peroxisome proliferator-activated receptor gamma/0.441
2r64740Cyclin-dependent kinase 22.7.11.220.441
2yejZZ3Heat shock protein HSP 90-alpha/0.441
2zazGK1Mitogen-activated protein kinase 14/0.441
3ey9TDPPyruvate dehydrogenase [ubiquinone]1.2.5.10.441
3flwFLWMitogen-activated protein kinase 14/0.441
3hcrCHDFerrochelatase, mitochondrial4.99.1.10.441
3my5RFZCyclin-dependent kinase 22.7.11.220.441
3nr4PYVAbscisic acid receptor PYL2/0.441
3nu9478Gag-Pol polyprotein3.4.23.160.441
3rni21ZCyclin-dependent kinase 22.7.11.220.441
3sw1FMNSensory box protein/0.441
3u5sFADFAD-linked sulfhydryl oxidase ALR1.8.3.20.441
3we45FIRibosomal protein S6 kinase beta-12.7.11.10.441
4bcpT3CCyclin-dependent kinase 22.7.11.220.441
4cd2FOLDihydrofolate reductase1.5.1.30.441
4dqf017Gag-Pol polyprotein/0.441
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
4fl2ANPTyrosine-protein kinase SYK2.7.10.20.441
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.441
4nwzFADFAD-dependent pyridine nucleotide-disulfide oxidoreductase/0.441
4qnaX11Serine/threonine-protein kinase 242.7.11.10.441
4rbs0RVMetallo-beta-lactamase type 2/0.441
1ckpPVBCyclin-dependent kinase 22.7.11.220.440
1e6eFADNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.440
1ffi2NCGag-Pol polyprotein3.4.23.160.440
1p44GEQEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
1s9pDESEstrogen-related receptor gamma/0.440
1vyw292Cyclin-dependent kinase 22.7.11.220.440
1w5xBE5Gag-Pol polyprotein3.4.23.160.440
1ykdCMPAdenylate cyclase/0.440
2ddoATPPyridoxine/pyridoxal/pyridoxamine kinase/0.440
2gpvOHTEstrogen-related receptor gamma/0.440
2nr4FMNConserved protein/0.440
2ovhAS0Progesterone receptor/0.440
2psvMUVProtease/0.440
2ywvADPPhosphoribosylaminoimidazole-succinocarboxamide synthase/0.440
3b8r887Vascular endothelial growth factor receptor 22.7.10.10.440
3bt9DEQHTH-type transcriptional regulator QacR/0.440
3k145352-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase/0.440
3k5uPFQAurora kinase A2.7.11.10.440
3kb3A8SAbscisic acid receptor PYL2/0.440
3mxdK53Gag-Pol polyprotein3.4.23.160.440
3nxvD2FDihydrofolate reductase1.5.1.30.440
3os33OSDual specificity mitogen-activated protein kinase kinase 12.7.12.20.440
3qpjN4IGag-Pol polyprotein3.4.23.160.440
3r1yX76Cyclin-dependent kinase 22.7.11.220.440
3r9uFADThioredoxin reductase/0.440
3rupADPBiotin carboxylase6.3.4.140.440
3smkCW714-3-3 protein sigma/0.440
3upjU03Gag-Pol polyprotein/0.440
4egiB2JHeat shock protein HSP 90-alpha/0.440
4ejh0QACytochrome P450 2A131.14.14.10.440
4eym0RXMitogen-activated protein kinase 132.7.11.240.440
4f9fGDPPutative glycosyltransferase/0.440
4g1z0VPVitamin D3 receptor A/0.440
4lyn1YGCyclin-dependent kinase 22.7.11.220.440
4nk92K5Fibroblast growth factor receptor 1/0.440
4o2z046Mitogen-activated protein kinase/0.440
4tv3ML9Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/0.440
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.440
4uajFADNa(+)-translocating NADH-quinone reductase subunit F/0.440
4wx1FDAUDP-galactopyranose mutase/0.440
5drdATPAurora kinase A2.7.11.10.440
3sn6P0GBeta-2 adrenergic receptor/0.440