sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1ve7 | 4NP | Acylamino-acid-releasing enzyme | 3.4.19.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1ve7 | 4NP | Acylamino-acid-releasing enzyme | 3.4.19.1 | 1.000 | |
| 1w19 | T1P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.511 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.509 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.504 | |
| 2vi5 | Y19 | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.504 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.503 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.501 | |
| 2uuk | 897 | Prothrombin | 3.4.21.5 | 0.501 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.501 | |
| 2o6h | INI | 6,7-dimethyl-8-ribityllumazine synthase 1 | 2.5.1.78 | 0.499 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.498 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.498 | |
| 1w19 | T5P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.496 | |
| 3dzk | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.496 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.496 | |
| 3wd9 | QPC | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.496 | |
| 4nv1 | TYD | Formyl transferase | / | 0.496 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.495 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.495 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.494 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.494 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.494 | |
| 1ejb | INJ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.493 | |
| 2vd0 | D27 | Hematopoietic prostaglandin D synthase | / | 0.493 | |
| 2f99 | AKV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.491 | |
| 4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.491 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.490 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.489 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.488 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.488 | |
| 1w29 | TS0 | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.488 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.488 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.487 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.487 | |
| 4l8v | NAP | Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase | 1.1.1.18 | 0.486 | |
| 1w19 | T4P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.485 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.485 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.485 | |
| 1tl7 | ONM | Adenylate cyclase type 2 | / | 0.484 | |
| 1tl7 | ONM | Adenylate cyclase type 5 | / | 0.484 | |
| 1xdu | SFG | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.484 | |
| 2e99 | B08 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.484 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.484 | |
| 3rj0 | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.484 | |
| 3swc | SAH | Histone-lysine N-methyltransferase EHMT1 | / | 0.484 | |
| 4c71 | 7RD | 3-oxoacyl-ACP synthase | / | 0.484 | |
| 4b68 | NAP | L-ornithine N(5)-monooxygenase | / | 0.483 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.482 | |
| 1fdu | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.481 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.481 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.481 | |
| 4nv1 | 0FX | Formyl transferase | / | 0.481 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.480 | |
| 3rgz | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.480 | |
| 1drf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.479 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.479 | |
| 2zc9 | 22U | Prothrombin | 3.4.21.5 | 0.479 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.479 | |
| 4n4v | 2GY | Tankyrase-1 | 2.4.2.30 | 0.479 | |
| 4uoh | ADP | Nucleoside diphosphate kinase | / | 0.479 | |
| 1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.478 | |
| 1nqx | RLP | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.478 | |
| 1r00 | SAH | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.478 | |
| 2yp0 | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.478 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.478 | |
| 3qj0 | QI3 | Botulinum neurotoxin type A | 3.4.24.69 | 0.478 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.478 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.477 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.477 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.476 | |
| 1pr4 | MTP | Purine nucleoside phosphorylase DeoD-type | / | 0.476 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.476 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.476 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.476 | |
| 4i4z | 2NE | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.476 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.475 | |
| 2zev | B71 | Geranylgeranyl pyrophosphate synthase | / | 0.475 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.475 | |
| 3s3v | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.475 | |
| 3v0m | 5GW | Histo-blood group ABO system transferase | / | 0.475 | |
| 4bfy | ZVY | Pantothenate kinase | 2.7.1.33 | 0.475 | |
| 1nqv | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.474 | |
| 1xp8 | AGS | Protein RecA | / | 0.474 | |
| 2bvs | 2CE | Prothrombin | 3.4.21.5 | 0.474 | |
| 2c9d | PHR | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.474 | |
| 2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.474 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.474 | |
| 3p0f | BAU | Uridine phosphorylase 2 | 2.4.2.3 | 0.474 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.473 | |
| 2c97 | JCL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.473 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.473 | |
| 3zia | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.473 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.473 | |
| 4dyp | 0MS | Nucleoprotein | / | 0.473 | |
| 4jpg | 1OX | Pyruvate kinase PKM | 2.7.1.40 | 0.473 | |
| 4nqg | CZH | Mitrocomin | / | 0.473 | |
| 4phl | PIL | Phosphodiesterase | / | 0.473 | |
| 5dp2 | NAP | CurF | / | 0.473 | |
| 1nqu | RDL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.472 | |
| 1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.472 | |
| 2c1z | KMP | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.472 | |
| 2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.472 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.472 | |
| 3gus | N11 | Glutathione S-transferase P | 2.5.1.18 | 0.472 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.472 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 1ypg | UIR | Prothrombin | 3.4.21.5 | 0.471 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.471 | |
| 3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.471 | |
| 4gn6 | TYL | Lactoperoxidase | 1.11.1.7 | 0.471 | |
| 6std | MS2 | Scytalone dehydratase | 4.2.1.94 | 0.471 | |
| 1icq | OPD | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.470 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.470 | |
| 1xr2 | C2F | 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase | 2.1.1.14 | 0.470 | |
| 2rdn | 1PL | 1-deoxypentalenic acid 11-beta-hydroxylase | 1.14.11.35 | 0.470 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.470 | |
| 3c1o | NAP | Eugenol synthase | / | 0.470 | |
| 3ggs | 2FD | Purine nucleoside phosphorylase | 2.4.2.1 | 0.470 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.470 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 4gd4 | 0WS | Lysine-specific demethylase 4A | 1.14.11 | 0.470 | |
| 1pf7 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.469 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.469 | |
| 1yci | NDF | Hypoxia-inducible factor 1-alpha inhibitor | 1.14.11.30 | 0.469 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.469 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.469 | |
| 4lsa | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.469 | |
| 1gt5 | BZQ | Odorant-binding protein | / | 0.468 | |
| 1s7g | NAD | NAD-dependent protein deacylase 2 | / | 0.468 | |
| 2mji | KTR | Fatty acid-binding protein, intestinal | / | 0.468 | |
| 2std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.468 | |
| 3n71 | SFG | Histone-lysine N-methyltransferase Smyd1 | / | 0.468 | |
| 3uyk | 0CX | Probable NDP-rhamnosyltransferase | / | 0.468 | |
| 4dyn | 0MR | Nucleoprotein | / | 0.468 | |
| 4kc1 | WS1 | Histo-blood group ABO system transferase | / | 0.468 | |
| 4wcx | SAM | Biotin and thiamin synthesis associated | / | 0.468 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.467 | |
| 1jdz | FMB | Purine nucleoside phosphorylase | / | 0.467 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.467 | |
| 2zhf | 49U | Prothrombin | 3.4.21.5 | 0.467 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.467 | |
| 3nxt | D2E | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.467 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.467 | |
| 4ise | 1FW | Glucokinase | 2.7.1.2 | 0.467 | |
| 4lzw | THM | Uridine phosphorylase | / | 0.467 | |
| 1dgh | NDP | Catalase | 1.11.1.6 | 0.466 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.466 | |
| 2pgt | GPR | Glutathione S-transferase P | 2.5.1.18 | 0.466 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 4ax9 | N5N | Prothrombin | 3.4.21.5 | 0.466 | |
| 4lxl | PD2 | Lysine-specific demethylase 4B | 1.14.11 | 0.466 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.466 | |
| 4std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.466 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.466 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.465 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.465 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.465 | |
| 2ejz | SAH | Diphthine synthase | / | 0.465 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.465 | |
| 3o56 | ZG1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.465 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.465 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.465 | |
| 4kfq | KFQ | Glutamate receptor ionotropic, NMDA 1 | / | 0.465 | |
| 5cho | FAD | Flavin reductase | / | 0.465 | |
| 1gaq | FAD | Ferredoxin | / | 0.464 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.464 | |
| 1r5g | AO1 | Methionine aminopeptidase 2 | / | 0.464 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.464 | |
| 2oac | GTB | Glutathione S-transferase P 1 | 2.5.1.18 | 0.464 | |
| 2vpr | TDC | Tetracycline repressor protein class H | / | 0.464 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 3cb2 | GDP | Tubulin gamma-1 chain | / | 0.464 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.464 | |
| 3ha3 | SAH | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.464 | |
| 3tfy | COA | N-alpha-acetyltransferase 50 | 2.3.1 | 0.464 | |
| 3u33 | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.464 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.464 | |
| 4bub | ADP | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--LD-lysine ligase | / | 0.464 | |
| 4dvi | 2IW | Tankyrase-1 | 2.4.2.30 | 0.464 | |
| 4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.464 | |
| 4xg1 | LLP | Diaminopimelate decarboxylase | / | 0.464 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.463 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.463 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.463 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.463 | |
| 3ean | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.463 | |
| 3igp | DT7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.463 | |
| 3v0n | 4GW | Histo-blood group ABO system transferase | / | 0.463 | |
| 4hej | 14D | Thymidylate kinase | / | 0.463 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.463 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.463 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.463 | |
| 7cat | NDP | Catalase | 1.11.1.6 | 0.463 | |
| 1cjw | COT | Serotonin N-acetyltransferase | / | 0.462 | |
| 1lnm | DTX | Bilin-binding protein | / | 0.462 | |
| 2f98 | NGV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.462 | |
| 2psj | CEI | Renilla-luciferin 2-monooxygenase | 1.13.12.5 | 0.462 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.462 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.462 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.462 | |
| 3g0y | P9A | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.462 | |
| 4irn | FAD | AnaB | / | 0.462 | |
| 4rsl | FAD | Fructosyl peptide oxidase | / | 0.462 | |
| 4ug9 | 1EW | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.462 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.461 | |
| 1rxj | BNI | Streptavidin | / | 0.461 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.461 | |
| 3csj | CBL | Glutathione S-transferase P | 2.5.1.18 | 0.461 | |
| 3gyf | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 3std | MQ0 | Scytalone dehydratase | 4.2.1.94 | 0.461 | |
| 4dan | 2FA | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.461 | |
| 4dh0 | MR8 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.461 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.461 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.461 | |
| 4n1g | CEI | Obelin | / | 0.461 | |
| 4utl | FNR | Xenobiotic reductase | / | 0.461 | |
| 1d3p | BT3 | Prothrombin | 3.4.21.5 | 0.460 | |
| 1w76 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 1z71 | L17 | Prothrombin | 3.4.21.5 | 0.460 | |
| 2iya | ZIO | Oleandomycin glycosyltransferase | / | 0.460 | |
| 2q94 | A04 | Methionine aminopeptidase | / | 0.460 | |
| 2x9g | LYA | Pteridine reductase | / | 0.460 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 3mj4 | URM | UDP-galactopyranose mutase | / | 0.460 | |
| 3ozc | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.460 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 4b2g | V1N | Uncharacterized protein | / | 0.460 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.460 | |
| 4boe | CLR | Japanin | / | 0.460 | |
| 4kc4 | WS3 | Histo-blood group ABO system transferase | / | 0.460 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.459 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 1ja1 | FMN | NADPH--cytochrome P450 reductase | / | 0.459 | |
| 1jra | FAD | FAD-linked sulfhydryl oxidase ERV2 | 1.8.3.2 | 0.459 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.459 | |
| 1tou | B1V | Fatty acid-binding protein, adipocyte | / | 0.459 | |
| 1yc2 | NAD | NAD-dependent protein deacylase 2 | / | 0.459 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 2lfo | GCH | Fatty acid-binding protein, liver | / | 0.459 | |
| 2w3m | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 2xnp | WCX | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.459 | |
| 2zsd | COA | Pantothenate kinase | 2.7.1.33 | 0.459 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.459 | |
| 3nxo | D2B | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 3o76 | GTB | Glutathione S-transferase P 1 | 2.5.1.18 | 0.459 | |
| 4c49 | HCY | Corticosteroid-binding globulin | / | 0.459 | |
| 4g2y | NI5 | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.459 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 3vw7 | VPX | Proteinase-activated receptor 1 | / | 0.459 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 1pgt | GTX | Glutathione S-transferase P | 2.5.1.18 | 0.458 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.458 | |
| 2a3b | CFF | Endochitinase B1 | 3.2.1.14 | 0.458 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.458 | |
| 3clr | FAD | Electron transfer flavoprotein subunit alpha | / | 0.458 | |
| 3ele | PLP | Aminotransferase | / | 0.458 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.458 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.458 | |
| 3n39 | FMN | Protein NrdI | / | 0.458 | |
| 3n5x | XFK | Nitric oxide synthase, brain | 1.14.13.39 | 0.458 | |
| 3p2o | NAD | Bifunctional protein FolD | / | 0.458 | |
| 3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.458 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.458 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.458 | |
| 4da6 | GA2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.458 | |
| 4wfr | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.458 | |
| 1o97 | FAD | Electron transfer flavoprotein subunit alpha | / | 0.457 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.457 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.457 | |
| 20gs | CBD | Glutathione S-transferase P | 2.5.1.18 | 0.457 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.457 | |
| 2g0g | SP0 | Peroxisome proliferator-activated receptor gamma | / | 0.457 | |
| 2rd2 | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.457 | |
| 2zda | 32U | Prothrombin | 3.4.21.5 | 0.457 | |
| 3b82 | NAD | Exotoxin A | 2.4.2.36 | 0.457 | |
| 3dhk | 23U | Prothrombin | 3.4.21.5 | 0.457 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.457 | |
| 3nu0 | 3TU | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 3qiy | QI1 | Botulinum neurotoxin type A | 3.4.24.69 | 0.457 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.457 | |
| 4ddr | MMV | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 4dlc | UMP | Deoxyuridine triphosphatase, putative | / | 0.457 | |
| 4hfp | 15U | Prothrombin | 3.4.21.5 | 0.457 | |
| 4ttj | FMC | Purine nucleoside phosphorylase DeoD-type | / | 0.457 | |
| 5bn3 | ADP | V-type ATP synthase alpha chain | / | 0.457 | |
| 5bn3 | ADP | NEQ263 | / | 0.457 | |
| 1acj | THA | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 1dlr | MXA | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1e63 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.456 | |
| 1i9q | IOF | Carbonic anhydrase 2 | 4.2.1.1 | 0.456 | |
| 1je1 | GMP | Purine nucleoside phosphorylase | / | 0.456 | |
| 1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.456 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.456 | |
| 2dxi | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.456 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.456 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.456 | |
| 3cuk | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.456 | |
| 3dop | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.456 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 3kig | DA4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.456 | |
| 4wlj | IK2 | Kynurenine--oxoglutarate transaminase 1 | 2.6.1.7 | 0.456 | |
| 1jf0 | CZH | Obelin | / | 0.455 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.455 | |
| 2zev | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.455 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.455 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.455 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.455 | |
| 3gi2 | GHW | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 3nn6 | HNK | 6-hydroxy-L-nicotine oxidase | / | 0.455 | |
| 3occ | DIH | Purine nucleoside phosphorylase DeoD-type | / | 0.455 | |
| 3pka | Y02 | Methionine aminopeptidase 2 | / | 0.455 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.455 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.455 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.455 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.454 | |
| 1jwt | BLI | Prothrombin | 3.4.21.5 | 0.454 | |
| 1uhh | CZP | Aequorin-2 | / | 0.454 | |
| 1xq0 | 4TR | Carbonic anhydrase 2 | 4.2.1.1 | 0.454 | |
| 2vq7 | NAP | Putative flavin-containing monooxygenase | / | 0.454 | |
| 2xda | JPS | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.454 | |
| 2xkc | 4VQ | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.454 | |
| 3n19 | FNR | Xenobiotic reductase | / | 0.454 | |
| 3pke | Y10 | Methionine aminopeptidase 2 | / | 0.454 | |
| 4e0u | 0MV | Cyclic dipeptide N-prenyltransferase | / | 0.454 | |
| 4ge9 | 0L0 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.454 | |
| 5f54 | TMP | Single-stranded-DNA-specific exonuclease | / | 0.454 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.453 | |
| 1kms | LIH | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1nqw | 5YL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.453 | |
| 1o2g | 696 | Prothrombin | 3.4.21.5 | 0.453 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 1oz0 | MS1 | Bifunctional purine biosynthesis protein PURH | 2.1.2.3 | 0.453 | |
| 1tu8 | GTX | Glutathione S-transferase 2 | 2.5.1.18 | 0.453 | |
| 1w4l | GL8 | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 2clf | F6F | Tryptophan synthase alpha chain | / | 0.453 | |
| 2ct8 | MSP | Methionine--tRNA ligase | 6.1.1.10 | 0.453 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.453 | |
| 2gmu | PDG | Putative pyridoxamine 5-phosphate-dependent dehydrase | / | 0.453 | |
| 2hxz | H7J | Cathepsin S | 3.4.22.27 | 0.453 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.453 | |
| 2zi2 | 24U | Prothrombin | 3.4.21.5 | 0.453 | |
| 3lzz | GDP | Uncharacterized protein | / | 0.453 | |
| 3ojw | FAD | NADPH--cytochrome P450 reductase | / | 0.453 | |
| 3pz3 | PZ3 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.453 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.453 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.453 | |
| 3zvm | ADP | Bifunctional polynucleotide phosphatase/kinase | 2.7.1.78 | 0.453 | |
| 4ap1 | NAP | Steroid monooxygenase | / | 0.453 | |
| 4cth | RDF | Neprilysin | / | 0.453 | |
| 4nhy | PD2 | Prolyl 3-hydroxylase OGFOD1 | 1.14.11 | 0.453 | |
| 1bl4 | AP1 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.452 | |
| 1dgg | NDP | Catalase | 1.11.1.6 | 0.452 | |
| 1qrq | NDP | Voltage-gated potassium channel subunit beta-2 | / | 0.452 | |
| 1u1g | BBB | Uridine phosphorylase | 2.4.2.3 | 0.452 | |
| 2a2d | ANP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.452 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 2zcv | NDP | Quinone oxidoreductase 2 | 1.6.5.2 | 0.452 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.452 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.452 | |
| 3q1k | ADP | D-alanine--D-alanine ligase A | 6.3.2.4 | 0.452 | |
| 3q7j | FBO | Tricorn protease-interacting factor F3 | 3.4.11 | 0.452 | |
| 3szg | NXX | Glutamine-dependent NAD(+) synthetase | 6.3.5.1 | 0.452 | |
| 4cmf | PXG | Uncharacterized protein | / | 0.452 | |
| 4kbn | 25U | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 4nt3 | ZAW | Lactoperoxidase | 1.11.1.7 | 0.452 | |
| 4rel | KMP | Glycosyltransferase | / | 0.452 | |
| 4s1i | PLP | Pyridoxal kinase, putative | / | 0.452 | |
| 4tti | FMC | Purine nucleoside phosphorylase DeoD-type | / | 0.452 | |
| 5d7o | AR6 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.452 | |
| 1al8 | DHP | Peroxisomal (S)-2-hydroxy-acid oxidase | 1.1.3.15 | 0.451 | |
| 1asc | NPL | Aspartate aminotransferase | 2.6.1.1 | 0.451 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.451 | |
| 1crb | RTL | Retinol-binding protein 1 | / | 0.451 | |
| 1ja0 | FAD | NADPH--cytochrome P450 reductase | / | 0.451 | |
| 1mu6 | CDA | Prothrombin | 3.4.21.5 | 0.451 | |
| 1ndz | FR5 | Adenosine deaminase | 3.5.4.4 | 0.451 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.451 | |
| 2clm | F6F | Tryptophan synthase alpha chain | / | 0.451 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.451 | |
| 2pau | D5M | 5'-deoxynucleotidase YfbR | / | 0.451 | |
| 2xiq | 5AD | Methylmalonyl-CoA mutase, mitochondrial | / | 0.451 | |
| 3c14 | FOK | Adenylate cyclase type 2 | / | 0.451 | |
| 3c14 | FOK | Adenylate cyclase type 5 | / | 0.451 | |
| 3dr7 | GPD | GDP-perosamine synthase | / | 0.451 | |
| 3juq | AKD | Phenazine biosynthesis protein A/B | / | 0.451 | |
| 3lfm | 3DT | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.451 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.451 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.451 | |
| 4fa3 | 0SL | Aldo-keto reductase family 1 member C3 | / | 0.451 | |
| 4gv7 | MEW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.451 | |
| 4wx2 | F6F | Tryptophan synthase alpha chain | / | 0.451 | |
| 4wx2 | F6F | Tryptophan synthase beta chain | 4.2.1.20 | 0.451 | |
| 4x7w | MVI | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.451 | |
| 1c7o | PPG | Hemolysin | / | 0.450 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1n95 | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.450 | |
| 1n95 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.450 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 1ppj | ANY | Cytochrome b | / | 0.450 | |
| 1pq6 | 965 | Oxysterols receptor LXR-beta | / | 0.450 | |
| 1v3q | 2DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.450 | |
| 1w1w | AGS | Structural maintenance of chromosomes protein 1 | / | 0.450 | |
| 1xm1 | GAH | Prothrombin | 3.4.21.5 | 0.450 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.450 | |
| 2nnq | T4B | Fatty acid-binding protein, adipocyte | / | 0.450 | |
| 2reh | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.450 | |
| 2y1t | DUD | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.450 | |
| 3e6e | DCS | Alanine racemase | / | 0.450 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.450 | |
| 4b1j | A1R | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.450 | |
| 4b67 | NAP | L-ornithine N(5)-monooxygenase | / | 0.450 | |
| 4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.450 | |
| 4e2y | JHZ | Methyltransferase | / | 0.450 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.450 | |
| 4keb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.450 | |
| 5d7q | 4I5 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.450 | |
| 1d9i | 00P | Prothrombin | 3.4.21.5 | 0.449 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.449 | |
| 1pua | COA | HAT A1 | / | 0.449 | |
| 1tll | FMN | Nitric oxide synthase, brain | 1.14.13.39 | 0.449 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 2poq | ISD | Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase | 1.3.1.20 | 0.449 | |
| 2r6h | FAD | Na(+)-translocating NADH-quinone reductase subunit F | / | 0.449 | |
| 2w3a | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 2xi4 | AFT | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 2yoj | 8Y6 | Genome polyprotein | 2.7.7.48 | 0.449 | |
| 3g58 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.449 | |
| 3gc4 | AAQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.449 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.449 | |
| 3i12 | ADP | D-alanine--D-alanine ligase A | 6.3.2.4 | 0.449 | |
| 3ufl | 508 | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 3upy | FOM | Oxidoreductase, putative | / | 0.449 | |
| 3zks | WZV | Beta-secretase 2 | 3.4.23.45 | 0.449 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.449 | |
| 4h7c | 10H | Aldo-keto reductase family 1 member C3 | / | 0.449 | |
| 4hs4 | FMN | Chromate reductase | / | 0.449 | |
| 4uof | DAT | Nucleoside diphosphate kinase | / | 0.449 | |
| 4uy6 | SAH | Histidine N-alpha-methyltransferase | / | 0.449 | |
| 1k9s | FM1 | Purine nucleoside phosphorylase DeoD-type | / | 0.448 | |
| 1n8w | COA | Malate synthase G | / | 0.448 | |
| 1oyn | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
| 1t4v | 14A | Prothrombin | 3.4.21.5 | 0.448 | |
| 1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 1w29 | TS1 | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.448 | |
| 1xvv | CCQ | L-carnitine CoA-transferase | / | 0.448 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.448 | |
| 2a2x | NA9 | Prothrombin | 3.4.21.5 | 0.448 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.448 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.448 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.448 | |
| 2g7y | MO9 | Cathepsin S | 3.4.22.27 | 0.448 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.448 | |
| 2nr4 | FMN | Conserved protein | / | 0.448 | |
| 2o8j | SAH | Histone-lysine N-methyltransferase EHMT2 | / | 0.448 | |
| 2od7 | A1R | NAD-dependent protein deacetylase HST2 | 3.5.1 | 0.448 | |
| 2r2m | I50 | Prothrombin | 3.4.21.5 | 0.448 | |
| 2xlr | NAP | Putative flavin-containing monooxygenase | / | 0.448 | |
| 3b4p | 3B4 | Phenazine biosynthesis protein A/B | / | 0.448 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3kr6 | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.448 | |
| 3syt | NAD | Glutamine-dependent NAD(+) synthetase | 6.3.5.1 | 0.448 | |
| 3wav | DWV | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | 3.1.4.39 | 0.448 | |
| 4afe | GGY | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.448 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 4bis | 8HQ | Lysine-specific demethylase 4A | 1.14.11 | 0.448 | |
| 4dyb | 0MH | Nucleoprotein | / | 0.448 | |
| 8cat | NDP | Catalase | 1.11.1.6 | 0.448 | |
| 1dlj | UGA | UDP-glucose 6-dehydrogenase | / | 0.447 | |
| 1fvp | FMA | Non-fluorescent flavoprotein | / | 0.447 | |
| 1i91 | INQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.447 | |
| 1lke | DOG | Bilin-binding protein | / | 0.447 | |
| 1mue | CDD | Prothrombin | 3.4.21.5 | 0.447 | |
| 1q1g | MTI | Purine nucleoside phosphorylase | / | 0.447 | |
| 1ro9 | 8BR | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.447 | |
| 1ypl | RA8 | Prothrombin | 3.4.21.5 | 0.447 | |
| 2fxu | BID | Actin, alpha skeletal muscle | / | 0.447 | |
| 2jgb | MGT | Eukaryotic translation initiation factor 4E type 2 | / | 0.447 | |
| 2xvv | 9DN | Serum albumin | / | 0.447 | |
| 2zg0 | 50U | Prothrombin | 3.4.21.5 | 0.447 | |
| 3b8x | G4M | Putative pyridoxamine 5-phosphate-dependent dehydrase | / | 0.447 | |
| 3f8s | PF2 | Dipeptidyl peptidase 4 | / | 0.447 | |
| 3n3a | FMN | Protein NrdI | / | 0.447 | |
| 3t85 | SG7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.447 | |
| 3zc3 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.447 | |
| 4bgi | I4I | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 4hld | 16T | Thymidylate kinase | / | 0.447 | |
| 4n4t | 2GV | Tankyrase-1 | 2.4.2.30 | 0.447 | |
| 4wdf | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.447 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 1euy | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.446 | |
| 1fdt | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.446 | |
| 1sd1 | FMC | S-methyl-5'-thioadenosine phosphorylase | / | 0.446 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.446 | |
| 1y1r | ANU | Uridine phosphorylase | 2.4.2.3 | 0.446 | |
| 1ygk | RRC | Pyridoxal kinase | 2.7.1.35 | 0.446 | |
| 2bsx | NOS | Purine nucleoside phosphorylase | / | 0.446 | |
| 2evc | FC3 | Methionine aminopeptidase | / | 0.446 | |
| 2pnu | ENM | Androgen receptor | / | 0.446 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.446 | |
| 2tpl | HPP | Tyrosine phenol-lyase | 4.1.99.2 | 0.446 | |
| 2yac | 937 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.446 | |
| 3c35 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.446 | |
| 3lfc | Z86 | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 3mau | PLR | Putative sphingosine-1-phosphate lyase | / | 0.446 | |
| 3pah | XDE | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.446 | |
| 4iah | 1DX | Alr2278 protein | / | 0.446 | |
| 4l0q | NAD | Alcohol dehydrogenase class-3 | / | 0.446 | |
| 4nv7 | COA | Arylamine N-acetyltransferase | / | 0.446 | |
| 4usq | FAD | Pyridine nucleotide-disulfide oxidoreductase | / | 0.446 | |
| 4yfy | 0FX | VioF | / | 0.446 | |
| 1s4p | GDP | Glycolipid 2-alpha-mannosyltransferase | / | 0.445 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.445 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.445 | |
| 1xh7 | R96 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.445 | |
| 1xh8 | R55 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.445 | |
| 2ab8 | MTP | Adenosine kinase | 2.7.1.20 | 0.445 | |
| 2c92 | TP6 | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.445 | |
| 2jc6 | QPP | Calcium/calmodulin-dependent protein kinase type 1D | 2.7.11.17 | 0.445 | |
| 2r0c | FAD | Putative FAD-monooxygenase | / | 0.445 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 3akl | ADP | Serine/threonine-protein kinase CtkA | 2.7.11.1 | 0.445 | |
| 3b6p | TMP | Three-prime repair exonuclease 1 | 3.1.11.2 | 0.445 | |
| 3caq | NDP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.445 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.445 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.445 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 3sqw | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.445 | |
| 3u5y | SCG | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.445 | |
| 3uaz | NOS | Purine nucleoside phosphorylase DeoD-type | / | 0.445 | |
| 4fkz | UD1 | UDP-N-acetylglucosamine 2-epimerase | 5.1.3.14 | 0.445 | |
| 4jq3 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.445 | |
| 4k38 | SAM | Anaerobic sulfatase-maturating enzyme | 1.8.98 | 0.445 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.445 | |
| 4opc | FDA | Conserved Archaeal protein | / | 0.445 | |
| 4xoq | F42 | Coenzyme F420:L-glutamate ligase | / | 0.445 | |
| 5cfl | C2E | Stimulator of interferon genes protein | / | 0.445 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.445 | |
| 4u16 | 3C0 | Muscarinic acetylcholine receptor M3 | / | 0.445 | |
| 1akb | PPD | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.444 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.444 | |
| 1fki | SB1 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.444 | |
| 1g60 | SAM | Modification methylase MboII | 2.1.1.72 | 0.444 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.444 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.444 | |
| 1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.444 | |
| 1ry8 | RUT | Aldo-keto reductase family 1 member C3 | / | 0.444 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 1thz | 326 | Bifunctional purine biosynthesis protein PURH | 2.1.2.3 | 0.444 | |
| 1uhj | CZB | Aequorin-2 | / | 0.444 | |
| 1z5u | CMP | Class B acid phosphatase | / | 0.444 | |
| 2c6c | 24I | Glutamate carboxypeptidase 2 | 3.4.17.21 | 0.444 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.444 | |
| 2rgx | AP5 | Adenylate kinase | / | 0.444 | |
| 3c4a | FAD | Protodeoxyviolaceinate monooxygenase | 1 | 0.444 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.444 | |
| 3oad | LPO | Renin | 3.4.23.15 | 0.444 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.444 | |
| 4g09 | 0VD | Histidinol dehydrogenase | / | 0.444 | |
| 4jq4 | IMN | Aldo-keto reductase family 1 member C2 | / | 0.444 | |
| 4mfp | COA | Uncharacterized protein | / | 0.444 | |
| 4qzu | RTL | Retinol-binding protein 2 | / | 0.444 | |
| 5d4u | SAM | Uncharacterized protein MJ0489 | / | 0.444 | |
| 1cs4 | FOK | Adenylate cyclase type 2 | / | 0.443 | |
| 1cs4 | FOK | Adenylate cyclase type 5 | / | 0.443 | |
| 1dgf | NDP | Catalase | 1.11.1.6 | 0.443 | |
| 1h66 | RH1 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 1o6r | R19 | Squalene--hopene cyclase | 4.2.1.129 | 0.443 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.443 | |
| 1sg0 | STL | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.443 | |
| 1xa4 | COA | L-carnitine CoA-transferase | / | 0.443 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 2bf4 | FMN | NADPH--cytochrome P450 reductase | / | 0.443 | |
| 2bxo | OPB | Serum albumin | / | 0.443 | |
| 2qw8 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.443 | |
| 2wpw | ACO | Orf14 | / | 0.443 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.443 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.443 | |
| 3dd1 | 25D | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.443 | |
| 3dla | NXX | Glutamine-dependent NAD(+) synthetase | 6.3.5.1 | 0.443 | |
| 3g1r | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.443 | |
| 3g72 | A6T | Renin | 3.4.23.15 | 0.443 | |
| 3ha5 | SFG | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.443 | |
| 3juq | AJD | Phenazine biosynthesis protein A/B | / | 0.443 | |
| 3k1w | BFX | Renin | 3.4.23.15 | 0.443 | |
| 3nxy | D2H | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3o57 | ZG2 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.443 | |
| 4b6u | M7G | Eukaryotic translation initiation factor 4E type 3 | / | 0.443 | |
| 4dya | 0MF | Nucleoprotein | / | 0.443 | |
| 4iae | 1DX | Alr2278 protein | / | 0.443 | |
| 4qx5 | CMP | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.443 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.443 | |
| 4wev | SUZ | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.443 | |
| 4x7z | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.443 | |
| 1bkf | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.442 | |
| 1c4u | IH1 | Prothrombin | 3.4.21.5 | 0.442 | |
| 1dli | UDX | UDP-glucose 6-dehydrogenase | / | 0.442 | |
| 1qpf | 858 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.442 | |
| 1swg | BTN | Streptavidin | / | 0.442 | |
| 1vp5 | NAP | Oxidoreductase, aldo/keto reductase family | / | 0.442 | |
| 1ype | UIP | Prothrombin | 3.4.21.5 | 0.442 | |
| 2cy2 | ACO | Probable acetyltransferase | / | 0.442 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.442 | |
| 2oad | GTB | Glutathione S-transferase P 1 | 2.5.1.18 | 0.442 | |
| 2r8o | T5X | Transketolase 1 | / | 0.442 | |
| 2uxp | CLM | HTH-type transcriptional regulator TtgR | / | 0.442 | |
| 2v3o | I26 | Prothrombin | 3.4.21.5 | 0.442 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.442 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 3ddw | 055 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.442 | |
| 3dwb | RDF | Endothelin-converting enzyme 1 | 3.4.24.71 | 0.442 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3f3y | 4OA | Bile salt sulfotransferase | 2.8.2.14 | 0.442 | |
| 3fr4 | F8A | Fatty acid-binding protein, adipocyte | / | 0.442 | |
| 3fw3 | ETS | Carbonic anhydrase 4 | 4.2.1.1 | 0.442 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.442 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.442 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.442 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 3ptz | UDX | UDP-glucose 6-dehydrogenase | 1.1.1.22 | 0.442 | |
| 3qpo | PFR | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
| 4a16 | H34 | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 4a1o | AMZ | Bifunctional purine biosynthesis protein PurH | 2.1.2.3 | 0.442 | |
| 4aos | NAP | Steroid monooxygenase | / | 0.442 | |
| 4ehy | ADP | Tetraacyldisaccharide 4'-kinase | / | 0.442 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.442 | |
| 4h6u | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.442 | |
| 4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4i6h | 1C8 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.442 | |
| 4kc2 | WS2 | Histo-blood group ABO system transferase | / | 0.442 | |
| 4zj8 | SUV | Orexin receptor type 1 | / | 0.442 | |
| 1f0l | APU | Diphtheria toxin | / | 0.441 | |
| 1fxu | GU7 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 1k4m | NAD | Nicotinate-nucleotide adenylyltransferase | 2.7.7.18 | 0.441 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.441 | |
| 1v48 | HA1 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 1ve3 | SAM | Uncharacterized protein | / | 0.441 | |
| 2aq7 | TL5 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.441 | |
| 2b01 | TUD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.441 | |
| 2c94 | TSF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.441 | |
| 2jh0 | 701 | Prothrombin | 3.4.21.5 | 0.441 | |
| 2tsr | UMP | Thymidylate synthase | 2.1.1.45 | 0.441 | |
| 3cso | XNI | Genome polyprotein | 2.7.7.48 | 0.441 | |
| 3eon | 341 | Glutaryl-CoA dehydrogenase | / | 0.441 | |
| 3ha7 | B32 | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.441 | |
| 3hgg | CHD | CmeR | / | 0.441 | |
| 3kmy | D8Y | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.441 | |
| 4b66 | NAP | L-ornithine N(5)-monooxygenase | / | 0.441 | |
| 4d7e | FAD | Putative lysine-N-oxygenase | / | 0.441 | |
| 4flk | Y10 | Methionine aminopeptidase 1 | / | 0.441 | |
| 4gxs | 0YS | Glutamate receptor 2 | / | 0.441 | |
| 4wct | FAD | Fructosyl amine:oxygen oxidoreductase | / | 0.441 | |
| 4z87 | GDP | Inosine-5'-monophosphate dehydrogenase | / | 0.441 | |
| 4zwp | M44 | Xaa-Pro dipeptidase | 3.4.13.9 | 0.441 | |
| 5ej7 | TD6 | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.441 | |
| 13gs | SAS | Glutathione S-transferase P | 2.5.1.18 | 0.440 | |
| 1dg7 | WRB | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1el4 | CTZ | Obelin | / | 0.440 | |
| 1fx9 | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.440 | |
| 1gj4 | 132 | Prothrombin | 3.4.21.5 | 0.440 | |
| 1pl6 | 572 | Sorbitol dehydrogenase | 1.1.1.14 | 0.440 | |
| 1re0 | AFB | ADP-ribosylation factor 1 | / | 0.440 | |
| 1re0 | AFB | ARF guanine-nucleotide exchange factor 1 | / | 0.440 | |
| 1tyt | FAD | Trypanothione reductase | 1.8.1.12 | 0.440 | |
| 1zp4 | C2F | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.440 | |
| 2jav | 5Z5 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.440 | |
| 2ok8 | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.440 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 2ptf | FMN | Uncharacterized protein MTH_863 | / | 0.440 | |
| 2qs1 | UB1 | Glutamate receptor ionotropic, kainate 1 | / | 0.440 | |
| 2x3j | ATP | AcsD | / | 0.440 | |
| 2xb8 | XNW | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.440 | |
| 2xlp | NAP | Putative flavin-containing monooxygenase | / | 0.440 | |
| 2zrz | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.440 | |
| 3gjw | GJW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.440 | |
| 3h2s | NDP | Putative NADH-flavin reductase | / | 0.440 | |
| 3ie3 | N11 | Glutathione S-transferase P | 2.5.1.18 | 0.440 | |
| 3mhi | J90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.440 | |
| 3n9j | EAA | Glutathione S-transferase P | 2.5.1.18 | 0.440 | |
| 3uay | ADN | Purine nucleoside phosphorylase DeoD-type | / | 0.440 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.440 | |
| 4b68 | FAD | L-ornithine N(5)-monooxygenase | / | 0.440 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 4k6i | 9RA | Retinoic acid receptor RXR-alpha | / | 0.440 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 4na4 | A1R | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.440 | |
| 4qjc | IXE | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 5kf2 | ACO | Predicted acetyltransferase | / | 0.440 |