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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4deg0JJHepatocyte growth factor receptor2.7.10.1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4deg0JJHepatocyte growth factor receptor2.7.10.11.000
4gg70J8Hepatocyte growth factor receptor2.7.10.10.668
4ap7F47Hepatocyte growth factor receptor2.7.10.10.650
2wgjVGHHepatocyte growth factor receptor2.7.10.10.624
3zze6XPHepatocyte growth factor receptor2.7.10.10.618
3zxzKRWHepatocyte growth factor receptor2.7.10.10.612
3zc5W9ZHepatocyte growth factor receptor2.7.10.10.601
4gg50J3Hepatocyte growth factor receptor2.7.10.10.594
4aoi4K0Hepatocyte growth factor receptor2.7.10.10.577
3a4pDFQHepatocyte growth factor receptor2.7.10.10.562
3zbx6XEHepatocyte growth factor receptor2.7.10.10.533
4kb81QOCasein kinase I isoform delta2.7.11.10.523
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.512
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.507
2vagV25Dual specificity protein kinase CLK12.7.12.10.505
4c02TAKActivin receptor type-12.7.11.300.505
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.497
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.497
2wkmPFYHepatocyte growth factor receptor2.7.10.10.494
3c50ADPRhodopsin kinase/0.493
5e8wSTUTGF-beta receptor type-12.7.11.300.490
2xa4AZ5Tyrosine-protein kinase JAK2/0.488
3hztJ60Calmodulin-like domain protein kinase isoform 3/0.487
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.486
1ir3ANPInsulin receptor2.7.10.10.486
3i81EBIInsulin-like growth factor 1 receptor2.7.10.10.486
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.486
1u3dFADCryptochrome-1/0.485
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.485
4ix6ADPUncharacterized protein/0.485
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.484
2c5nCK8Cyclin-dependent kinase 22.7.11.220.483
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.483
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.482
3iw4LW4Protein kinase C alpha type2.7.11.130.481
4gu94GUFocal adhesion kinase 12.7.10.20.481
4iwd1JCHepatocyte growth factor receptor2.7.10.10.481
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.481
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.480
4lm5Q17Serine/threonine-protein kinase pim-12.7.11.10.480
1e9hINRCyclin-dependent kinase 22.7.11.220.479
2j4z626Aurora kinase A2.7.11.10.479
2yeiXQIHeat shock protein HSP 90-alpha/0.479
3c4zADPRhodopsin kinase/0.479
4ewhT77Activated CDC42 kinase 1/0.479
2bkzSBCCyclin-dependent kinase 22.7.11.220.478
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.478
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.478
2iw94SPCyclin-dependent kinase 22.7.11.220.477
3zh8C58Protein kinase C iota type2.7.11.130.477
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.477
1py5PY1TGF-beta receptor type-12.7.11.300.476
1s6qTPBGag-Pol polyprotein2.7.7.490.476
2pe039Z3-phosphoinositide-dependent protein kinase 12.7.11.10.476
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.476
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.476
2vgoAD5Aurora kinase B-A2.7.11.10.475
3eyhIZATyrosine-protein kinase JAK1/0.475
3wi6YRZMAP kinase-activated protein kinase 22.7.11.10.475
4gfo0X2Non-receptor tyrosine-protein kinase TYK22.7.10.20.475
4xgxADPFAD:protein FMN transferase/0.475
1u4dDBQActivated CDC42 kinase 1/0.474
2xikJ60Serine/threonine-protein kinase 252.7.11.10.474
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.474
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.473
4lopSB4Mitogen-activated protein kinase 14/0.473
5auvAGIDeath-associated protein kinase 12.7.11.10.473
1rx1NAPDihydrofolate reductase1.5.1.30.472
1rx8FOLDihydrofolate reductase1.5.1.30.472
2fwzH71Heat shock protein HSP 90-alpha/0.472
2x1nX1NCyclin-dependent kinase 22.7.11.220.472
2izsBRQCasein kinase I isoform gamma-32.7.11.10.471
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.471
4fv6E57Mitogen-activated protein kinase 12.7.11.240.471
4krcAGSCyclin-dependent protein kinase PHO852.7.11.220.471
4lmuQUESerine/threonine-protein kinase pim-12.7.11.10.471
5auzGENDeath-associated protein kinase 12.7.11.10.471
1v59FADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.470
2uzlC94Cyclin-dependent kinase 22.7.11.220.470
2vmyFFOSerine hydroxymethyltransferase/0.470
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.470
3kgaLX9MAP kinase-activated protein kinase 22.7.11.10.470
4uyg73BBromodomain-containing protein 2/0.470
4wboANWRhodopsin kinase/0.470
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.470
4y95746Tyrosine-protein kinase/0.470
1ol7ADPAurora kinase A2.7.11.10.469
1vjy460TGF-beta receptor type-12.7.11.300.469
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.469
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.469
3w0pADPHygromycin-B 4-O-kinase2.7.1.1630.469
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.469
4dymIYZActivin receptor type-12.7.11.300.469
4grb0XGCasein kinase II subunit alpha2.7.11.10.469
4hnc0UTMandelate racemase/0.469
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.468
4hgl0YOCasein kinase I isoform gamma-32.7.11.10.468
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.468
5eccNAPDehydrofolate reductase type I/0.468
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.467
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.467
3bgzVX3Serine/threonine-protein kinase pim-12.7.11.10.467
3v5j0F2Tyrosine-protein kinase ITK/TSK2.7.10.20.467
4jqeANPCasein kinase II subunit alpha2.7.11.10.467
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.467
1kl2FONSerine hydroxymethyltransferase/0.466
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.466
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.466
1aq1STUCyclin-dependent kinase 22.7.11.220.465
1lsjNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.465
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.465
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.465
2j2iLY4Serine/threonine-protein kinase pim-12.7.11.10.465
2jedLG8Protein kinase C theta type2.7.11.130.465
2jkqVG8Focal adhesion kinase 12.7.10.20.465
3bheBZNGag-Pol polyprotein3.4.23.160.465
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.465
5ai5BSUBifunctional epoxide hydrolase 23.1.3.760.465
1rbyKEUTrifunctional purine biosynthetic protein adenosine-32.1.2.20.464
1uy9PU6Heat shock protein HSP 90-alpha/0.464
2izrBRKCasein kinase I isoform gamma-32.7.11.10.464
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.464
4az0S61Lysosomal protective protein3.4.16.50.464
4qmzB49Serine/threonine-protein kinase 242.7.11.10.464
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.463
2fwyH64Heat shock protein HSP 90-alpha/0.463
2iw84SPCyclin-dependent kinase 22.7.11.220.463
3r02UNMSerine/threonine-protein kinase pim-12.7.11.10.463
3s0o50ZCyclin-dependent kinase 22.7.11.220.463
3uixQ17Serine/threonine-protein kinase pim-12.7.11.10.463
3vetADPnebramycin 5' synthase6.1.2.20.463
4at3LTIBDNF/NT-3 growth factors receptor2.7.10.10.463
1wvxBD4Death-associated protein kinase 12.7.11.10.462
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.462
2hr8SAHDiphthine synthase/0.462
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.462
2wotZZGTGF-beta receptor type-12.7.11.300.462
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.462
3qd33Q53-phosphoinositide-dependent protein kinase 12.7.11.10.462
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.462
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.462
4dgo0JWCasein kinase II subunit alpha2.7.11.10.462
4fnyI3KALK tyrosine kinase receptor2.7.10.10.462
4foc0UUALK tyrosine kinase receptor2.7.10.10.462
4im01FVSerine/threonine-protein kinase TBK12.7.11.10.462
4looSB4Mitogen-activated protein kinase 14/0.462
4mf029ZTyrosine-protein kinase ITK/TSK2.7.10.20.462
4yuqKS1Calmodulin-like domain protein kinase/0.462
5aaaVGHALK tyrosine kinase receptor2.7.10.10.462
1ny3ADPMAP kinase-activated protein kinase 22.7.11.10.461
1o6yACPSerine/threonine-protein kinase PknB2.7.11.10.461
3w33W19Epidermal growth factor receptor2.7.10.10.461
4fob0USALK tyrosine kinase receptor2.7.10.10.461
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.461
4hgs15GCasein kinase I isoform gamma-32.7.11.10.461
4loqSB4Mitogen-activated protein kinase 14/0.461
5av2KMPDeath-associated protein kinase 12.7.11.10.461
5av4GENDeath-associated protein kinase 12.7.11.10.461
3uzaT4GAdenosine receptor A2a/0.461
1bygSTUTyrosine-protein kinase CSK/0.460
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.460
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.460
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.460
2ydkYDKSerine/threonine-protein kinase Chk12.7.11.10.460
3hvcGG5Mitogen-activated protein kinase 14/0.460
3igoANPCalmodulin-domain protein kinase 1, putative/0.460
4c62XWWTyrosine-protein kinase JAK2/0.460
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.460
4kbc1QJCasein kinase I isoform delta2.7.11.10.460
1di8DTQCyclin-dependent kinase 22.7.11.220.459
1k7fIAVTryptophan synthase alpha chain/0.459
1uycPU7Heat shock protein HSP 90-alpha/0.459
2c6tDT5Cyclin-dependent kinase 22.7.11.220.459
2w1eL0EAurora kinase A2.7.11.10.459
3krwBA1Beta-adrenergic receptor kinase 12.7.11.150.459
4f650S9Fibroblast growth factor receptor 1/0.459
4nc3ERM5-hydroxytryptamine receptor 2B/0.459
1g5sI17Cyclin-dependent kinase 22.7.11.220.458
1qnfFADDeoxyribodipyrimidine photo-lyase4.1.99.30.458
2uzeC95Cyclin-dependent kinase 22.7.11.220.458
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.458
3fzr3JZProtein-tyrosine kinase 2-beta2.7.10.20.458
3lctADPALK tyrosine kinase receptor2.7.10.10.458
4bcpT3CCyclin-dependent kinase 22.7.11.220.458
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.458
4hyu1BKMitogen-activated protein kinase 82.7.11.240.458
4mwhATPCasein kinase II subunit alpha2.7.11.10.458
1drhNAPDihydrofolate reductase1.5.1.30.457
1r78FMDCyclin-dependent kinase 22.7.11.220.457
1rfvADPPyridoxal kinase2.7.1.350.457
2h55DZ8Heat shock protein HSP 90-alpha/0.457
2ojg19AMitogen-activated protein kinase 12.7.11.240.457
2ok7FADFerredoxin--NADP reductase, apicoplast/0.457
2owuSAHDiphthine synthase/0.457
2pziAXXSerine/threonine-protein kinase PknG2.7.11.10.457
2q6cHR13-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.340.457
2xiyXIYSerine/threonine-protein kinase pim-12.7.11.10.457
3a7jADPSerine/threonine-protein kinase 242.7.11.10.457
3c1xCKKHepatocyte growth factor receptor2.7.10.10.457
3cd57HI3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.340.457
3mtlFEFCyclin-dependent kinase 162.7.11.220.457
3oom507Activin receptor type-12.7.11.300.457
3pmy41LEndothiapepsin3.4.23.220.457
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.457
3we45FIRibosomal protein S6 kinase beta-12.7.11.10.457
4eutBX7Serine/threonine-protein kinase TBK12.7.11.10.457
4jr7GNPCasein kinase II subunit alpha2.7.11.10.457
1u54ACPActivated CDC42 kinase 1/0.456
4gu610NFocal adhesion kinase 12.7.10.20.456
5cyoGDPSeptin-9/0.456
1j7kATPHolliday junction ATP-dependent DNA helicase RuvB/0.455
1nzfUPGDNA beta-glucosyltransferase/0.455
2a1y5GPGMP reductase/0.455
2ittAEEEpidermal growth factor receptor2.7.10.10.455
2j0k4STFocal adhesion kinase 12.7.10.20.455
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.455
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.455
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.455
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.455
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.455
4bchT7ZCyclin-dependent kinase 92.7.11.220.455
4g160VMCasein kinase I isoform gamma-32.7.11.10.455
4i22IREEpidermal growth factor receptor2.7.10.10.455
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.455
4o0sADNAurora kinase A2.7.11.10.455
1vyw292Cyclin-dependent kinase 22.7.11.220.454
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.454
2ay84TBAromatic-amino-acid aminotransferase2.6.1.570.454
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.454
2chlDKICasein kinase I isoform gamma-32.7.11.10.454
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.454
2eufLQQCyclin-dependent kinase 62.7.11.220.454
2iw6QQ2Cyclin-dependent kinase 22.7.11.220.454
2w1gL0GAurora kinase A2.7.11.10.454
2zbaZBATrichothecene 3-O-acetyltransferase/0.454
3at3ATKCasein kinase II subunit alpha2.7.11.10.454
3fwfCAMCamphor 5-monooxygenase1.14.15.10.454
4aacAAVMitogen-activated protein kinase 14/0.454
4c4jX21Dual specificity protein kinase TTK2.7.12.10.454
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.454
4ib4ERM5-hydroxytryptamine receptor 2B/0.454
4l8vNAPInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase1.1.1.180.454
5fwnNAPPutative dehydrogenase/0.454
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.453
2ijmATPFocal adhesion kinase 12.7.10.20.453
3bhh5CPCalcium/calmodulin-dependent protein kinase type II subunit beta2.7.11.170.453
3n0tOPYDipeptidyl peptidase 23.4.14.20.453
3nglNAPBifunctional protein FolD/0.453
3nizADPCdc2-like CDK2/CDC28 like protein kinase/0.453
3owj1ELCasein kinase II subunit alpha2.7.11.10.453
3r83Z14Cyclin-dependent kinase 22.7.11.220.453
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.453
4othDRNSerine/threonine-protein kinase N1/0.453
5cvfATPCasein kinase II subunit alpha2.7.11.10.453
5f0a1FBcGMP-dependent protein kinase, putative/0.453
1csnATPCasein kinase I homolog 12.7.11.10.452
1fpqSAMIsoliquiritigenin 2'-O-methyltransferase/0.452
1oitHDTCyclin-dependent kinase 22.7.11.220.452
1ojtFADDihydrolipoyl dehydrogenase/0.452
1pjkANPCasein kinase II subunit alpha2.7.11.10.452
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.452
2etm7PYFocal adhesion kinase 12.7.10.20.452
2h96893Mitogen-activated protein kinase 82.7.11.240.452
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.452
3gwfFADCyclohexanone monooxygenase/0.452
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
4gk2L66Ephrin type-A receptor 32.7.10.10.452
4ix5ANPUncharacterized protein/0.452
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.452
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
1jpaANPEphrin type-B receptor 22.7.10.10.451
1rx8NAPDihydrofolate reductase1.5.1.30.451
2bl9CP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.451
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.451
2wxvWXVCyclin-dependent kinase 22.7.11.220.451
3at4CCKCasein kinase II subunit alpha2.7.11.10.451
3kn5ANPRibosomal protein S6 kinase alpha-52.7.11.10.451
3lf0ATPNitrogen regulatory protein P-II/0.451
3nwxKVSGag-Pol polyprotein3.4.23.160.451
3o0iP54Heat shock protein HSP 90-alpha/0.451
4brxKGWFocal adhesion kinase 12.7.10.20.451
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.451
4ccbOFGALK tyrosine kinase receptor2.7.10.10.451
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.451
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.451
1vruAAPGag-Pol polyprotein2.7.7.490.450
1yw2PGJMitogen-activated protein kinase 14/0.450
2biyATP3-phosphoinositide-dependent protein kinase 12.7.11.10.450
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.450
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.450
3l1sZ92Glycogen synthase kinase-3 beta2.7.11.260.450
3mvl38PMitogen-activated protein kinase 14/0.450
4b99R4LMitogen-activated protein kinase 72.7.11.240.450
4ez50RSCyclin-dependent kinase 62.7.11.220.450
4gub0Y4Casein kinase II subunit alpha2.7.11.10.450
4kz01UJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
4u9zCOAAlpha-tubulin N-acetyltransferase 1/0.450
1fvv107Cyclin-dependent kinase 22.7.11.220.449
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.449
1nzdUPGDNA beta-glucosyltransferase/0.449
1oi9N20Cyclin-dependent kinase 22.7.11.220.449
1tezFADDeoxyribodipyrimidine photo-lyase4.1.99.30.449
2acxANPG protein-coupled receptor kinase 62.7.11.160.449
2w1dL0DAurora kinase A2.7.11.10.449
3fln3FNMitogen-activated protein kinase 14/0.449
3nww3NWMitogen-activated protein kinase 14/0.449
3rk909ZCyclin-dependent kinase 22.7.11.220.449
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.449
4bdhWVISerine/threonine-protein kinase Chk22.7.11.10.449
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.449
4mvfSTUCalcium-dependent protein kinase 22.7.11.10.449
4xlvACPInsulin receptor2.7.10.10.449
1fvt106Cyclin-dependent kinase 22.7.11.220.448
1gij2PUCyclin-dependent kinase 22.7.11.220.448
1mvsDTMDihydrofolate reductase1.5.1.30.448
1qoqIGPTryptophan synthase alpha chain/0.448
1uy7PU4Heat shock protein HSP 90-alpha/0.448
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.448
2e9p77ASerine/threonine-protein kinase Chk12.7.11.10.448
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.448
2wihP48Cyclin-dependent kinase 22.7.11.220.448
2xizXIZSerine/threonine-protein kinase pim-12.7.11.10.448
2ydjYDJSerine/threonine-protein kinase Chk12.7.11.10.448
3czr3CZCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.448
3pxkPXKFocal adhesion kinase 12.7.10.20.448
3tneRITCandidapepsin-13.4.23.240.448
3uvr06FMitogen-activated protein kinase 14/0.448
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.448
4fkv61KCyclin-dependent kinase 22.7.11.220.448
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.448
4k8aK8AFocal adhesion kinase 12.7.10.20.448
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.448
1hk5T44Serum albumin/0.447
1phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.447
1q3wATUGlycogen synthase kinase-3 beta2.7.11.260.447
1uu3LY43-phosphoinositide-dependent protein kinase 12.7.11.10.447
1y91CT9Cyclin-dependent kinase 22.7.11.220.447
2cig1DGDihydrofolate reductase1.5.1.30.447
2dwbANPAurora kinase A2.7.11.10.447
2h94FADLysine-specific histone demethylase 1A10.447
2itnANPEpidermal growth factor receptor2.7.10.10.447
2itpAEEEpidermal growth factor receptor2.7.10.10.447
2qg2A91Heat shock protein HSP 90-alpha/0.447
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.447
2yee2ECHeat shock protein HSP 90-alpha/0.447
3a60STURibosomal protein S6 kinase beta-12.7.11.10.447
3axwTIDCasein kinase II subunit alpha2.7.11.10.447
3bhy7CPDeath-associated protein kinase 3/0.447
3cy3JN5Serine/threonine-protein kinase pim-12.7.11.10.447
3flwFLWMitogen-activated protein kinase 14/0.447
3h0sB38Acetyl-CoA carboxylase/0.447
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.447
3nr4PYVAbscisic acid receptor PYL2/0.447
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.447
3rni21ZCyclin-dependent kinase 22.7.11.220.447
3w0sANPHygromycin-B 4-O-kinase2.7.1.1630.447
4az3S35Lysosomal protective protein3.4.16.50.447
4bb6HD1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.447
4dgmAGICasein kinase II subunit alpha2.7.11.10.447
4kb81QNCasein kinase I isoform delta2.7.11.10.447
4l17DNQGlutamate receptor 2/0.447
4l8u9AZSerum albumin/0.447
4n6z2HWSerine/threonine-protein kinase pim-12.7.11.10.447
4nk92K5Fibroblast growth factor receptor 1/0.447
4qmwKS1Serine/threonine-protein kinase 242.7.11.10.447
5dgzL20Serine/threonine-protein kinase pim-12.7.11.10.447
1ai9NDPDihydrofolate reductase1.5.1.30.446
1u2gAPRNAD(P) transhydrogenase subunit alpha part 11.6.1.20.446
1wvySTUDeath-associated protein kinase 12.7.11.10.446
2b7aIZATyrosine-protein kinase JAK2/0.446
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.446
2e8hSAHDiphthine synthase/0.446
2hfuMEVMevalonate kinase/0.446
2izuP01Casein kinase I isoform gamma-32.7.11.10.446
2o2yTCLEnoyl-ACP reductase/0.446
2uztSS3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
2ykbYKBHeat shock protein HSP 90-alpha/0.446
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.446
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
3qlsNDPDihydrofolate reductase1.5.1.30.446
3r7iX9ICyclin-dependent kinase 22.7.11.220.446
3slkNDPPolyketide synthase extender module 2/0.446
4e4m0NHTyrosine-protein kinase JAK2/0.446
4f700STCyclin-dependent kinase 82.7.11.220.446
4nh82LCHeat shock protein HSP 90-alpha/0.446
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.446
4rqvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.446
5aacVGHALK tyrosine kinase receptor2.7.10.10.446
3emlZMAAdenosine receptor A2a/0.446
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.445
1ppjANYCytochrome b/0.445
2btsU32Cyclin-dependent kinase 22.7.11.220.445
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.445
2huvSAHDiphthine synthase/0.445
2wmvZYVSerine/threonine-protein kinase Chk12.7.11.10.445
3bgpVX1Serine/threonine-protein kinase pim-12.7.11.10.445
3gggNADPrephenate dehydrogenase/0.445
3t3r9PLCytochrome P450 2A61.14.130.445
3v8t477Tyrosine-protein kinase ITK/TSK2.7.10.20.445
3w0nANPHygromycin-B 4-O-kinase2.7.1.1630.445
3zewSTUEphrin type-B receptor 42.7.10.10.445
4e730NRMitogen-activated protein kinase 82.7.11.240.445
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
4hnf16WCasein kinase I isoform delta2.7.11.10.445
4jhz1KVBeta-glucuronidase3.2.1.310.445
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.445
4oacADPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.445
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.445
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.444
1f28F89Thymidylate synthase2.1.1.450.444
1h1q2A6Cyclin-dependent kinase 22.7.11.220.444
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.444
1tehNADAlcohol dehydrogenase class-31.1.1.10.444
1v59NADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.444
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.444
2g28TDKPyruvate dehydrogenase E1 component1.2.4.10.444
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.444
2j5xGSPADP-ribosylation factor 6/0.444
2jkoBIJFocal adhesion kinase 12.7.10.20.444
2ojj82AMitogen-activated protein kinase 12.7.11.240.444
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.444
2uzdC85Cyclin-dependent kinase 22.7.11.220.444
3g5qFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.444
3oibFDAPutative acyl-CoA dehydrogenase/0.444
3s2pPMUCyclin-dependent kinase 22.7.11.220.444
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.444
3zksWZVBeta-secretase 23.4.23.450.444
4jboWPHAurora kinase A2.7.11.10.444
4wq4ATPtRNA N6-adenosine threonylcarbamoyltransferase/0.444
5dt4ATPAurora kinase A2.7.11.10.444
1e8zSTUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
1eh4IC1Casein kinase I homolog 12.7.11.10.443
1f17NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.443
1j39UPGDNA beta-glucosyltransferase/0.443
1p4fDRGDeath-associated protein kinase 12.7.11.10.443
1pkdUCNCyclin-dependent kinase 22.7.11.220.443
1tqmANPRIO-type serine/threonine-protein kinase Rio22.7.11.10.443
1vyzN5BCyclin-dependent kinase 22.7.11.220.443
1zarADPRIO-type serine/threonine-protein kinase Rio22.7.11.10.443
2bfyH1NAurora kinase B-A2.7.11.10.443
2cchATPCyclin-dependent kinase 22.7.11.220.443
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.443
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.443
3anmNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.443
3d4pNADL-lactate dehydrogenase 11.1.1.270.443
3e5aVX6Aurora kinase A2.7.11.10.443
3fhxPXLPyridoxal kinase2.7.1.350.443
3hx4ANPCalmodulin-domain protein kinase 1/0.443
3oroAGSSerine/threonine protein kinase/0.443
3qaiXNNKetohexokinase/0.443
3qlwN22Dihydrofolate reductase1.5.1.30.443
4b144XBGlycylpeptide N-tetradecanoyltransferase/0.443
4bdfH3RSerine/threonine-protein kinase Chk22.7.11.10.443
4f081RSTyrosine-protein kinase JAK2/0.443
4gmy0X5Tyrosine-protein kinase JAK2/0.443
4nm9FADBifunctional protein PutA/0.443
5dulNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.443
1gqtACPRibokinase/0.442
1m2rMNYCasein kinase II subunit alpha2.7.11.10.442
1p44GEQEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
1t0lNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.442
1uymPU3Heat shock protein HSP 90-beta/0.442
1yi4ADNSerine/threonine-protein kinase pim-12.7.11.10.442
2emuSAHDiphthine synthase/0.442
2h2qNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.442
2pvlP55Casein kinase II subunit alpha2.7.11.10.442
2pvnP63Casein kinase II subunit alpha2.7.11.10.442
2yac937Serine/threonine-protein kinase PLK12.7.11.210.442
3bu5ATPInsulin receptor2.7.10.10.442
3c4eC4ESerine/threonine-protein kinase pim-12.7.11.10.442
3nj0PYVAbscisic acid receptor PYL2/0.442
3plsANPMacrophage-stimulating protein receptor2.7.10.10.442
3q9xEMOCasein kinase II subunit alpha2.7.11.10.442
3qlrNDPDihydrofolate reductase1.5.1.30.442
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.442
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.442
4deaNHIAurora kinase A2.7.11.10.442
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.442
4g1wG1WMitogen-activated protein kinase 82.7.11.240.442
4gii0X6Non-receptor tyrosine-protein kinase TYK22.7.10.20.442
4gyzD5MTyrosyl-DNA phosphodiesterase 23.1.40.442
4hni16WCasein kinase I isoform epsilon2.7.11.10.442
4hvb19PPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
4ixgIXGDihydrofolate reductase1.5.1.30.442
4qmlANPSerine/threonine-protein kinase 242.7.11.10.442
4wh3ATPN-acetylhexosamine 1-kinase2.7.1.1620.442
1bsvNDPGDP-L-fucose synthase/0.441
1rfqLARActin, alpha skeletal muscle/0.441
1uu7BI23-phosphoinositide-dependent protein kinase 12.7.11.10.441
1wn3HXCPhenylacetic acid degradation protein PaaI/0.441
2d29FADAcyl-CoA dehydrogenase/0.441
2oj9BMIInsulin-like growth factor 1 receptor2.7.10.10.441
2vcmM11Isopenicillin N synthase1.21.3.10.441
2w17I19Cyclin-dependent kinase 22.7.11.220.441
3l8p0CEAngiopoietin-1 receptor2.7.10.10.441
3ox1695Ribosyldihydronicotinamide dehydrogenase [quinone]/0.441
3poz03PEpidermal growth factor receptor2.7.10.10.441
3ql8X01Cyclin-dependent kinase 22.7.11.220.441
3t8oATPRhodopsin kinase/0.441
3tqaNDPDihydrofolate reductase/0.441
3vg9ZMAAdenosine receptor A2a/0.441
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
4c58824Cyclin-G-associated kinase2.7.11.10.441
4fr0SAMArsenic methyltransferase/0.441
4nb6444Nuclear receptor ROR-gamma/0.441
4rupH97Vitamin D3 receptor A/0.441
5i2hAGIO-methyltransferase family 2/0.441
1bxqPP8Penicillopepsin-13.4.23.200.440
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.440
1v35NAIEnoyl-ACP reductase/0.440
1xjdSTUProtein kinase C theta type2.7.11.130.440
1zaoATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.440
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.440
2c3iIYZSerine/threonine-protein kinase pim-12.7.11.10.440
2duv371Cyclin-dependent kinase 22.7.11.220.440
2e07SAHDiphthine synthase/0.440
2fumMIXSerine/threonine-protein kinase PknB2.7.11.10.440
2p2xSAHDiphthine synthase/0.440
2r64740Cyclin-dependent kinase 22.7.11.220.440
2w9hTOPDihydrofolate reductase1.5.1.30.440
2x3nFADProbable FAD-dependent monooxygenase/0.440
3dafFEG5,10-methenyltetrahydromethanopterin hydrogenase1.12.98.20.440
3ibqATPPyridoxal kinase/0.440
3icrCOACoenzyme A disulfide reductase/0.440
3mdvCL6Cholesterol 24-hydroxylase/0.440
3nga3NGCasein kinase II subunit alpha2.7.11.10.440
3ns2PYVAbscisic acid receptor PYL2/0.440
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.440
3uxhUXHRibosyldihydronicotinamide dehydrogenase [quinone]/0.440
3v0p4GWHisto-blood group ABO system transferase/0.440
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.440
3vs6VSHTyrosine-protein kinase HCK2.7.10.20.440
3zep1NXTyrosine-protein kinase JAK32.7.10.20.440
4bcqTJFCyclin-dependent kinase 22.7.11.220.440
4bdgP3JSerine/threonine-protein kinase Chk22.7.11.10.440
4bqh9VUUDP-N-acetylglucosamine pyrophosphorylase, putative/0.440
4fhj0TZPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
4fkr45KCyclin-dependent kinase 22.7.11.220.440
4mf129YTyrosine-protein kinase ITK/TSK2.7.10.20.440
4wujFMNGlycoside hydrolase family 15, cellulose signaling associated protein envoy/0.440
4y93746Tyrosine-protein kinase/0.440
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.440
5cwa0GAAnthranilate synthase component 14.1.3.270.440
5drdATPAurora kinase A2.7.11.10.440