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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3qd33Q53-phosphoinositide-dependent protein kinase 12.7.11.1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3qd33Q53-phosphoinositide-dependent protein kinase 12.7.11.11.000
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.736
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.722
3qd03Q43-phosphoinositide-dependent protein kinase 12.7.11.10.717
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.703
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.679
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.630
3qcx3Q23-phosphoinositide-dependent protein kinase 12.7.11.10.600
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.589
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.582
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.575
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.570
3nuuJOZ3-phosphoinositide-dependent protein kinase 12.7.11.10.566
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.563
1uu3LY43-phosphoinositide-dependent protein kinase 12.7.11.10.561
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.560
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.560
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.559
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.558
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.557
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.556
2hog710Serine/threonine-protein kinase Chk12.7.11.10.554
4rqvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.552
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.550
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.550
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.548
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.546
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.546
3nuyJPZ3-phosphoinositide-dependent protein kinase 12.7.11.10.546
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.545
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.544
5av4GENDeath-associated protein kinase 12.7.11.10.544
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.541
3t8oATPRhodopsin kinase/0.540
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.540
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.538
2biyATP3-phosphoinositide-dependent protein kinase 12.7.11.10.538
1z5mLI83-phosphoinositide-dependent protein kinase 12.7.11.10.535
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.534
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.534
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.533
4ct2ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.532
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.531
2pe039Z3-phosphoinositide-dependent protein kinase 12.7.11.10.531
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.530
4fkv61KCyclin-dependent kinase 22.7.11.220.529
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.528
3zh8C58Protein kinase C iota type2.7.11.130.528
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.526
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.526
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.525
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.524
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.524
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.522
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.522
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.521
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.519
3gubGUBDeath-associated protein kinase 12.7.11.10.518
4bdgP3JSerine/threonine-protein kinase Chk22.7.11.10.518
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.518
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.517
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.516
3orzBI43-phosphoinositide-dependent protein kinase 12.7.11.10.516
1wvxBD4Death-associated protein kinase 12.7.11.10.515
3rmf20ZCyclin-dependent kinase 22.7.11.220.515
2w17I19Cyclin-dependent kinase 22.7.11.220.514
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.514
4ftq4HKSerine/threonine-protein kinase Chk12.7.11.10.514
5auvAGIDeath-associated protein kinase 12.7.11.10.514
3rak03ZCyclin-dependent kinase 22.7.11.220.513
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.513
5auwQUEDeath-associated protein kinase 12.7.11.10.513
1uu7BI23-phosphoinositide-dependent protein kinase 12.7.11.10.512
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.512
2in6839Wee1-like protein kinase2.7.10.20.512
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.512
4ftjH8KSerine/threonine-protein kinase Chk12.7.11.10.512
1oiyN41Cyclin-dependent kinase 22.7.11.220.511
4bdfH3RSerine/threonine-protein kinase Chk22.7.11.10.511
3gu5ANPDeath-associated protein kinase 12.7.11.10.510
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.509
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.509
3amaSKEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.508
3rpy27ZCyclin-dependent kinase 22.7.11.220.507
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.506
3ral04ZCyclin-dependent kinase 22.7.11.220.506
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.506
3gu6ADPDeath-associated protein kinase 12.7.11.10.505
4eutBX7Serine/threonine-protein kinase TBK12.7.11.10.505
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.504
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.504
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.504
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.503
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.503
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.502
2vv9IM9Cyclin-dependent kinase 22.7.11.220.502
2wmrZYRSerine/threonine-protein kinase Chk12.7.11.10.502
3a62STURibosomal protein S6 kinase beta-12.7.11.10.502
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.502
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.502
3s1h56ZCyclin-dependent kinase 22.7.11.220.501
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.501
2wmtZYTSerine/threonine-protein kinase Chk12.7.11.10.500
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.500
2wmvZYVSerine/threonine-protein kinase Chk12.7.11.10.500
4qmpDKISerine/threonine-protein kinase 242.7.11.10.500
5av047XDeath-associated protein kinase 12.7.11.10.500
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.499
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.499
4fsyHK7Serine/threonine-protein kinase Chk12.7.11.10.499
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.499
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.498
2iw84SPCyclin-dependent kinase 22.7.11.220.498
2qhn582Serine/threonine-protein kinase Chk12.7.11.10.498
4acm7YGCyclin-dependent kinase 22.7.11.220.498
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.498
4ftaH5KSerine/threonine-protein kinase Chk12.7.11.10.498
4fx360KCyclin-dependent kinase 22.7.11.220.498
1bygSTUTyrosine-protein kinase CSK/0.497
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.497
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.497
1e9hINRCyclin-dependent kinase 22.7.11.220.496
1fvv107Cyclin-dependent kinase 22.7.11.220.496
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.495
3v8t477Tyrosine-protein kinase ITK/TSK2.7.10.20.495
3zep1NXTyrosine-protein kinase JAK32.7.10.20.495
4enyJ19Serine/threonine-protein kinase pim-12.7.11.10.495
1oi9N20Cyclin-dependent kinase 22.7.11.220.494
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.494
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.494
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.494
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.494
2z2w770Wee1-like protein kinase2.7.10.20.494
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.494
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.493
2uzbC75Cyclin-dependent kinase 22.7.11.220.493
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.493
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.493
5dt0SKEAurora kinase A2.7.11.10.493
2x1nX1NCyclin-dependent kinase 22.7.11.220.492
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.492
4fg9ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.492
2yexYEXSerine/threonine-protein kinase Chk12.7.11.10.491
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.491
4jqeANPCasein kinase II subunit alpha2.7.11.10.491
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.490
1rekB8LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.490
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.490
3iok1P6Tyrosine-protein kinase JAK2/0.490
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.490
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.489
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.488
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.488
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.488
1uu8BI13-phosphoinositide-dependent protein kinase 12.7.11.10.487
2izt23DCasein kinase I isoform gamma-32.7.11.10.487
2wtiWTISerine/threonine-protein kinase Chk22.7.11.10.487
3bqr4RBDeath-associated protein kinase 3/0.487
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.487
4fsmHK1Serine/threonine-protein kinase Chk12.7.11.10.487
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.487
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.486
2x6dX6DAurora kinase A2.7.11.10.486
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.486
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.486
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.486
1pkdUCNCyclin-dependent kinase 22.7.11.220.485
1uu9BI33-phosphoinositide-dependent protein kinase 12.7.11.10.485
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.485
3ezvEZVCyclin-dependent kinase 22.7.11.220.485
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.485
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.485
4dgo0JWCasein kinase II subunit alpha2.7.11.10.485
4l3l5FIRibosomal protein S6 kinase beta-12.7.11.10.485
2btsU32Cyclin-dependent kinase 22.7.11.220.484
2w06FRVCyclin-dependent kinase 22.7.11.220.484
3c4xATPRhodopsin kinase/0.484
4bdaVFBSerine/threonine-protein kinase Chk22.7.11.10.484
4yhjAN2G protein-coupled receptor kinase 42.7.11.160.484
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.483
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.483
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.483
4k33ACPFibroblast growth factor receptor 32.7.10.10.483
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.482
3r9dX6BCyclin-dependent kinase 22.7.11.220.481
3we45FIRibosomal protein S6 kinase beta-12.7.11.10.481
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.481
4hvh19RTyrosine-protein kinase JAK32.7.10.20.481
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.480
2xikJ60Serine/threonine-protein kinase 252.7.11.10.480
4bdiHAUSerine/threonine-protein kinase Chk22.7.11.10.480
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.480
4mf129YTyrosine-protein kinase ITK/TSK2.7.10.20.480
3qc9ADPRhodopsin kinase/0.479
3uli1N3Cyclin-dependent kinase 22.7.11.220.479
2wtjWTJSerine/threonine-protein kinase Chk22.7.11.10.478
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.478
4qmzB49Serine/threonine-protein kinase 242.7.11.10.478
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.477
4ft3H1KSerine/threonine-protein kinase Chk12.7.11.10.477
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.477
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.477
1ke5LS1Cyclin-dependent kinase 22.7.11.220.476
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.475
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.475
3ggfGVDSerine/threonine-protein kinase 26/0.475
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.475
2cchATPCyclin-dependent kinase 22.7.11.220.474
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.474
2wxvWXVCyclin-dependent kinase 22.7.11.220.474
3tnwF18Cyclin-dependent kinase 22.7.11.220.474
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.473
2uzlC94Cyclin-dependent kinase 22.7.11.220.473
3a7hATPSerine/threonine-protein kinase 242.7.11.10.473
3gxlQIGTGF-beta receptor type-12.7.11.300.473
4fv9E71Mitogen-activated protein kinase 12.7.11.240.473
5av2KMPDeath-associated protein kinase 12.7.11.10.473
1urwI1PCyclin-dependent kinase 22.7.11.220.472
1vjy460TGF-beta receptor type-12.7.11.300.472
2izuP01Casein kinase I isoform gamma-32.7.11.10.472
4gmy0X5Tyrosine-protein kinase JAK2/0.472
4jia1K3Tyrosine-protein kinase JAK2/0.472
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.472
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.471
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.471
2c6tDT5Cyclin-dependent kinase 22.7.11.220.471
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.471
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.471
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.471
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.471
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.471
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.471
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.471
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.471
4fko20KCyclin-dependent kinase 22.7.11.220.471
4o0sADNAurora kinase A2.7.11.10.471
4qnaX11Serine/threonine-protein kinase 242.7.11.10.471
5auzGENDeath-associated protein kinase 12.7.11.10.471
5c7oNADGlyceraldehyde-3-phosphate dehydrogenase, testis-specific1.2.1.120.471
1yolS03Proto-oncogene tyrosine-protein kinase Src2.7.10.20.470
2vd5BI8Myotonin-protein kinase2.7.11.10.470
2xf04UBSerine/threonine-protein kinase Chk12.7.11.10.470
3a7jADPSerine/threonine-protein kinase 242.7.11.10.470
3c4wATPRhodopsin kinase/0.470
3kn5ANPRibosomal protein S6 kinase alpha-52.7.11.10.470
3sw418KCyclin-dependent kinase 22.7.11.220.470
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.470
4fto3HKSerine/threonine-protein kinase Chk12.7.11.10.470
4l3j5FIRibosomal protein S6 kinase beta-12.7.11.10.470
1jkkANPDeath-associated protein kinase 12.7.11.10.469
2ym3YM3Serine/threonine-protein kinase Chk12.7.11.10.469
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.469
3i60E86Mitogen-activated protein kinase 12.7.11.240.469
3s2pPMUCyclin-dependent kinase 22.7.11.220.469
3unk0BYCyclin-dependent kinase 22.7.11.220.469
4fv8E63Mitogen-activated protein kinase 12.7.11.240.469
5auxKMPDeath-associated protein kinase 12.7.11.10.469
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.468
2b7aIZATyrosine-protein kinase JAK2/0.468
2vttLZDCyclin-dependent kinase 22.7.11.220.468
2ycfYCFSerine/threonine-protein kinase Chk22.7.11.10.468
4bdhWVISerine/threonine-protein kinase Chk22.7.11.10.468
4jr7GNPCasein kinase II subunit alpha2.7.11.10.468
2c4g514Cyclin-dependent kinase 22.7.11.220.467
2j0m4STFocal adhesion kinase 12.7.10.20.467
2w05FRTCyclin-dependent kinase 22.7.11.220.467
3dfcANPDeath-associated protein kinase 12.7.11.10.467
4bgh3I6Cyclin-dependent kinase 22.7.11.220.467
4c4f7CEDual specificity protein kinase TTK2.7.12.10.467
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.467
4qmlANPSerine/threonine-protein kinase 242.7.11.10.467
1y91CT9Cyclin-dependent kinase 22.7.11.220.466
3rni21ZCyclin-dependent kinase 22.7.11.220.466
4brxKGWFocal adhesion kinase 12.7.10.20.466
4fg8ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.466
4j97ACPFibroblast growth factor receptor 2/0.466
2i40BLZCyclin-dependent kinase 22.7.11.220.465
2j0k4STFocal adhesion kinase 12.7.10.20.465
3bhy7CPDeath-associated protein kinase 3/0.465
3bu5ATPInsulin receptor2.7.10.10.465
4g170VNCasein kinase I isoform gamma-32.7.11.10.465
4im2BX7Serine/threonine-protein kinase TBK12.7.11.10.465
1gih1PUCyclin-dependent kinase 22.7.11.220.464
1m2rMNYCasein kinase II subunit alpha2.7.11.10.464
2izrBRKCasein kinase I isoform gamma-32.7.11.10.464
2uzdC85Cyclin-dependent kinase 22.7.11.220.464
2wihP48Cyclin-dependent kinase 22.7.11.220.464
3otuBI43-phosphoinositide-dependent protein kinase 12.7.11.10.464
3qtzX42Cyclin-dependent kinase 22.7.11.220.464
1aq1STUCyclin-dependent kinase 22.7.11.220.463
1q5kTMUGlycogen synthase kinase-3 beta2.7.11.260.463
1x8b824Wee1-like protein kinase2.7.10.20.463
1yvj4STTyrosine-protein kinase JAK32.7.10.20.463
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.463
2yaaATPDeath-associated protein kinase 2/0.463
3umw596Serine/threonine-protein kinase pim-12.7.11.10.463
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.463
4bddZ0OSerine/threonine-protein kinase Chk22.7.11.10.463
5dpvSKEAurora kinase A2.7.11.10.463
1pkgADPMast/stem cell growth factor receptor Kit2.7.10.10.462
1zys199Serine/threonine-protein kinase Chk12.7.11.10.462
2eufLQQCyclin-dependent kinase 62.7.11.220.462
2j0j4STFocal adhesion kinase 12.7.10.20.462
4dgnLU2Casein kinase II subunit alpha2.7.11.10.462
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.462
4o0wADNAurora kinase A2.7.11.10.462
4ysjADPCalmodulin-like domain protein kinase/0.462
1u54ACPActivated CDC42 kinase 1/0.461
1v0oINRCell division control protein 2 homolog2.7.11.220.461
2gjlFMNNitronate monooxygenase1.13.12.160.461
2yn8STUEphrin type-B receptor 42.7.10.10.461
3a8wATPProtein kinase C iota type2.7.11.130.461
3sw719KCyclin-dependent kinase 22.7.11.220.461
4c58824Cyclin-G-associated kinase2.7.11.10.461
4fks46KCyclin-dependent kinase 22.7.11.220.461
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.461
1jpaANPEphrin type-B receptor 22.7.10.10.460
1xjdSTUProtein kinase C theta type2.7.11.130.460
2cmwOLPCasein kinase I isoform gamma-12.7.11.10.460
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.460
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.460
4jik1KOSerine/threonine-protein kinase Chk12.7.11.10.460
4qpmADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.460
2b9jADPMitogen-activated protein kinase FUS32.7.11.240.459
3at4CCKCasein kinase II subunit alpha2.7.11.10.459
3qu0X40Cyclin-dependent kinase 22.7.11.220.459
3zewSTUEphrin type-B receptor 42.7.10.10.459
4a9uA9USerine/threonine-protein kinase Chk22.7.11.10.459
4g160VMCasein kinase I isoform gamma-32.7.11.10.459
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.459
5dr9SKEAurora kinase A2.7.11.10.459
1oguST8Cyclin-dependent kinase 22.7.11.220.458
2pvnP63Casein kinase II subunit alpha2.7.11.10.458
4fkr45KCyclin-dependent kinase 22.7.11.220.458
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.457
2b9iADPMitogen-activated protein kinase FUS32.7.11.240.457
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.457
2ckeIQUDeath-associated protein kinase 2/0.457
2dwbANPAurora kinase A2.7.11.10.457
2ydkYDKSerine/threonine-protein kinase Chk12.7.11.10.457
3be9P04Casein kinase II subunit alpha2.7.11.10.457
3bi6396Wee1-like protein kinase2.7.10.20.457
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
4hvg19QTyrosine-protein kinase JAK32.7.10.20.457
4lopSB4Mitogen-activated protein kinase 14/0.457
2etm7PYFocal adhesion kinase 12.7.10.20.456
3q9xEMOCasein kinase II subunit alpha2.7.11.10.456
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.456
4ajfF03cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.456
4im01FVSerine/threonine-protein kinase TBK12.7.11.10.456
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.456
2acxANPG protein-coupled receptor kinase 62.7.11.160.455
3my5RFZCyclin-dependent kinase 22.7.11.220.455
3nynSGVG protein-coupled receptor kinase 62.7.11.160.455
3r1qX75Cyclin-dependent kinase 22.7.11.220.455
4fob0USALK tyrosine kinase receptor2.7.10.10.455
1cdeGARPhosphoribosylglycinamide formyltransferase/0.454
1wvySTUDeath-associated protein kinase 12.7.11.10.454
2qo9ANPEphrin type-A receptor 32.7.10.10.454
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.454
3rpv26ZCyclin-dependent kinase 22.7.11.220.454
3rvg17PTyrosine-protein kinase JAK2/0.454
3u8w09JMitogen-activated protein kinase 14/0.454
3wowANPCasein kinase II subunit alpha2.7.11.10.454
4nka2K7Fibroblast growth factor receptor 1/0.454
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.454
5dosATPAurora kinase A2.7.11.10.454
1gii1PUCyclin-dependent kinase 22.7.11.220.453
1h5rTHMGlucose-1-phosphate thymidylyltransferase 1/0.453
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.453
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.453
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.453
2vr1ATFBiotin carboxylase6.3.4.140.453
2wmxZY6Serine/threonine-protein kinase Chk12.7.11.10.453
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.453
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.453
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.453
3lltANPProtein serine/threonine kinase-1/0.453
3nlb5BESerine/threonine-protein kinase Chk12.7.11.10.453
3qtuX44Cyclin-dependent kinase 22.7.11.220.453
3qtxX43Cyclin-dependent kinase 22.7.11.220.453
4c61LMMTyrosine-protein kinase JAK2/0.453
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.453
4qmySTUSerine/threonine-protein kinase 242.7.11.10.453
4r8qADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.453
1f17NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.452
1lsoNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.452
1p4fDRGDeath-associated protein kinase 12.7.11.10.452
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.452
2x9fX9FEphrin type-B receptor 42.7.10.10.452
3l8p0CEAngiopoietin-1 receptor2.7.10.10.452
4bcmT7ZCyclin-dependent kinase 22.7.11.220.452
4c62XWWTyrosine-protein kinase JAK2/0.452
4ek610KCyclin-dependent kinase 22.7.11.220.452
4eomATPCyclin-dependent kinase 22.7.11.220.452
4eooATPCyclin-dependent kinase 22.7.11.220.452
4wboANWRhodopsin kinase/0.452
1q3wATUGlycogen synthase kinase-3 beta2.7.11.260.451
2hmaSAMtRNA-specific 2-thiouridylase MnmA/0.451
2j0lANPFocal adhesion kinase 12.7.10.20.451
3rk708ZCyclin-dependent kinase 22.7.11.220.451
3ttiKBIMitogen-activated protein kinase 102.7.11.240.451
4c4iX20Dual specificity protein kinase TTK2.7.12.10.451
4iaq2GM5-hydroxytryptamine receptor 1B/0.451
4qo9627Serine/threonine-protein kinase 242.7.11.10.451
5dmzADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.451
5e8wSTUTGF-beta receptor type-12.7.11.300.451
1uv5BRWGlycogen synthase kinase-3 beta2.7.11.260.450
1ywgNADGlyceraldehyde-3-phosphate dehydrogenase/0.450
2c475IDCasein kinase I isoform gamma-2/0.450
2c6lDT4Cyclin-dependent kinase 22.7.11.220.450
2izsBRQCasein kinase I isoform gamma-32.7.11.10.450
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.450
4bdbODOSerine/threonine-protein kinase Chk22.7.11.10.450
4bi0Z0WDual specificity protein kinase TTK2.7.12.10.450
4c4g7RODual specificity protein kinase TTK2.7.12.10.450
4f640S8Fibroblast growth factor receptor 1/0.450
4fki09KCyclin-dependent kinase 22.7.11.220.450
4qq3XMPInosine-5'-monophosphate dehydrogenase/0.450
4xgxADPFAD:protein FMN transferase/0.450
5c8wPCGcGMP-dependent protein kinase 22.7.11.120.450
5e92ANPTGF-beta receptor type-22.7.11.300.450
1j1bANPGlycogen synthase kinase-3 beta2.7.11.260.449
2c5nCK8Cyclin-dependent kinase 22.7.11.220.449
2dbvNDPGlyceraldehyde-3-phosphate dehydrogenase/0.449
2pmlANPUncharacterized protein/0.449
2wipP49Cyclin-dependent kinase 22.7.11.220.449
2wmsZYSSerine/threonine-protein kinase Chk12.7.11.10.449
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.449
3lcdBDYMacrophage colony-stimulating factor 1 receptor2.7.10.10.449
3qlsNDPDihydrofolate reductase1.5.1.30.449
3r9oZ71Cyclin-dependent kinase 22.7.11.220.449
3w33W19Epidermal growth factor receptor2.7.10.10.449
4aguD15Cyclin-dependent kinase-like 1/0.449
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.449
4ezj0SCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
4ftn2HKSerine/threonine-protein kinase Chk12.7.11.10.449
4i6aHMG3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.449
4ienCOAPutative acyl-CoA hydrolase/0.449
5aacVGHALK tyrosine kinase receptor2.7.10.10.449
5drdATPAurora kinase A2.7.11.10.449
5dt3ATPAurora kinase A2.7.11.10.449
1y8yCT7Cyclin-dependent kinase 22.7.11.220.448
1zrzBI1Protein kinase C iota type2.7.11.130.448
2nmxM25Carbonic anhydrase 14.2.1.10.448
2r3lSCWCyclin-dependent kinase 22.7.11.220.448
2xmyCDKCyclin-dependent kinase 22.7.11.220.448
3rk507ZCyclin-dependent kinase 22.7.11.220.448
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.448
4ctaATPCinA-like protein/0.448
4eor4SPCyclin-dependent kinase 22.7.11.220.448
4fkw62KCyclin-dependent kinase 22.7.11.220.448
4fmqANPMitogen-activated protein kinase 12.7.11.240.448
4fv1EK4Mitogen-activated protein kinase 12.7.11.240.448
4grb0XGCasein kinase II subunit alpha2.7.11.10.448
4hvi19STyrosine-protein kinase JAK32.7.10.20.448
4w9wYDJBMP-2-inducible protein kinase2.7.11.10.448
1g5sI17Cyclin-dependent kinase 22.7.11.220.447
2a4zBYMPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
2obyNAPQuinone oxidoreductase PIG310.447
2yiqYIQSerine/threonine-protein kinase Chk22.7.11.10.447
3axwTIDCasein kinase II subunit alpha2.7.11.10.447
3c50ADPRhodopsin kinase/0.447
3fwjCAMCamphor 5-monooxygenase1.14.15.10.447
3icrCOACoenzyme A disulfide reductase/0.447
3pxkPXKFocal adhesion kinase 12.7.10.20.447
3s4qNK0Mitogen-activated protein kinase 14/0.447
4hgs15GCasein kinase I isoform gamma-32.7.11.10.447
1vyzN5BCyclin-dependent kinase 22.7.11.220.446
2ijmATPFocal adhesion kinase 12.7.10.20.446
2uzeC95Cyclin-dependent kinase 22.7.11.220.446
2zb3NDPProstaglandin reductase 21.3.1.480.446
3m42HGFMAP kinase-activated protein kinase 22.7.11.10.446
3prsRITEndothiapepsin3.4.23.220.446
4gk2L66Ephrin type-A receptor 32.7.10.10.446
4gk3L87Ephrin type-A receptor 32.7.10.10.446
4gvjADPNon-receptor tyrosine-protein kinase TYK22.7.10.20.446
4krcAGSCyclin-dependent protein kinase PHO852.7.11.220.446
4l4cCAMCamphor 5-monooxygenase1.14.15.10.446
4mcb21WtRNA (guanine-N(1)-)-methyltransferase2.1.1.2280.446
4oj4DIFPeroxisome proliferator-activated receptor gamma/0.446
1di8DTQCyclin-dependent kinase 22.7.11.220.445
1oiuN76Cyclin-dependent kinase 22.7.11.220.445
1qnfFADDeoxyribodipyrimidine photo-lyase4.1.99.30.445
1w0xOLOCyclin-dependent kinase 22.7.11.220.445
2i51FMNPyridoxamine 5'-phosphate oxidase-related, FMN-binding/0.445
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.445
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.445
3kc3MK2MAP kinase-activated protein kinase 22.7.11.10.445
3lctADPALK tyrosine kinase receptor2.7.10.10.445
3mfrANPPeripheral plasma membrane protein CASK2.7.11.10.445
3ztxZTXAurora kinase B-A2.7.11.10.445
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
4d0l093Phosphatidylinositol 4-kinase beta2.7.1.670.445
4fkj11KCyclin-dependent kinase 22.7.11.220.445
4fv5EK9Mitogen-activated protein kinase 12.7.11.240.445
4n57ADPAPH(2'')-Id/0.445
4nifANPMitogen-activated protein kinase 12.7.11.240.445
5e8ySTUTGF-beta receptor type-22.7.11.300.445
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
1ppm0P1Penicillopepsin-13.4.23.200.444
1xr1ANPSerine/threonine-protein kinase pim-12.7.11.10.444
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.444
2csnCKICasein kinase I homolog 12.7.11.10.444
2vrx447Aurora kinase B-A2.7.11.10.444
2vuw5IDSerine/threonine-protein kinase haspin2.7.11.10.444
3elySAHMethyltransferase/0.444
3krwBA1Beta-adrenergic receptor kinase 12.7.11.150.444
3nux3NVCyclin-dependent kinase 62.7.11.220.444
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
4ek816KCyclin-dependent kinase 22.7.11.220.444
4ez30S0Cyclin-dependent kinase 22.7.11.220.444
4fstHK4Serine/threonine-protein kinase Chk12.7.11.10.444
4g3rCAMCamphor 5-monooxygenase1.14.15.10.444
4i4e1BQFocal adhesion kinase 12.7.10.20.444
4iqlFMNEnoyl-(Acyl-carrier-protein) reductase II/0.444
5ap7SVEDual specificity protein kinase TTK2.7.12.10.444
6cp4CAMCamphor 5-monooxygenase1.14.15.10.444
1k6tXN1Gag-Pol polyprotein3.4.23.160.443
1mp8ADPFocal adhesion kinase 12.7.10.20.443
1om1IQACasein kinase II subunit alpha2.7.11.10.443
1qvnFRIInterleukin-2/0.443
1xkkFMMEpidermal growth factor receptor2.7.10.10.443
2cppCAMCamphor 5-monooxygenase1.14.15.10.443
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.443
2uxoTACHTH-type transcriptional regulator TtgR/0.443
3py0SU9Cyclin-dependent kinase 22.7.11.220.443
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.443
3zlx5EZDual specificity mitogen-activated protein kinase kinase 12.7.12.20.443
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.443
4bbhYBNGlycylpeptide N-tetradecanoyltransferase/0.443
4btjATPTau-tubulin kinase 12.7.11.10.443
4ivb1J5Tyrosine-protein kinase JAK1/0.443
1orrNADCDP-paratose 2-epimerase/0.442
1py5PY1TGF-beta receptor type-12.7.11.300.442
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.442
2cx8SAHRibosomal RNA small subunit methyltransferase E/0.442
2gjnFMNNitronate monooxygenase1.13.12.160.442
2ijmADPFocal adhesion kinase 12.7.10.20.442
2yerTQ1Serine/threonine-protein kinase Chk12.7.11.10.442
3wi6YRZMAP kinase-activated protein kinase 22.7.11.10.442
3zk5Z18Cytochrome P450 monooxygenase PikC/0.442
4btjADPTau-tubulin kinase 12.7.11.10.442
4fv6E57Mitogen-activated protein kinase 12.7.11.240.442
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.442
4k771Q4Tyrosine-protein kinase JAK1/0.442
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.442
1finATPCyclin-dependent kinase 22.7.11.220.441
1ol5ADPAurora kinase A2.7.11.10.441
1phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.441
1wbpADPSRSF protein kinase 12.7.11.10.441
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
2cn8DBQSerine/threonine-protein kinase Chk22.7.11.10.441
2gdo12CSerine/threonine-protein kinase Chk12.7.11.10.441
2x4f16XMyosin light chain kinase family member 42.7.11.10.441
2z97CAMCamphor 5-monooxygenase1.14.15.10.441
2zv2609Calcium/calmodulin-dependent protein kinase kinase 22.7.11.170.441
3bhh5CPCalcium/calmodulin-dependent protein kinase type II subunit beta2.7.11.170.441
3bhtMFRCyclin-dependent kinase 22.7.11.220.441
3kpkFADSulfide-quinone reductase/0.441
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.441
3sqq99ZCyclin-dependent kinase 22.7.11.220.441
4anmWULCasein kinase II subunit alpha2.7.11.10.441
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
4b99R4LMitogen-activated protein kinase 72.7.11.240.441
4c57FEFCyclin-G-associated kinase2.7.11.10.441
4hgt15GCasein kinase I isoform delta2.7.11.10.441
4iarERM5-hydroxytryptamine receptor 1B/0.441
5bpfADPD-alanine--D-alanine ligase/0.441
1oitHDTCyclin-dependent kinase 22.7.11.220.440
1szjNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.440
2nnpROCProtease/0.440
2pywADPMethylthioribose kinase2.7.1.1000.440
2w1fL0FAurora kinase A2.7.11.10.440
2y7jB49Phosphorylase b kinase gamma catalytic chain, liver/testis isoform2.7.11.190.440
3cr0809Wee1-like protein kinase2.7.10.20.440
3d84NDPDihydrofolate reductase1.5.1.30.440
3eyhIZATyrosine-protein kinase JAK1/0.440
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.440
3qlg1N1Proto-oncogene tyrosine-protein kinase Src2.7.10.20.440
3qtrX36Cyclin-dependent kinase 22.7.11.220.440
3r1sX73Cyclin-dependent kinase 22.7.11.220.440
3sheI85MAP kinase-activated protein kinase 32.7.11.10.440
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.440
4fkt48KCyclin-dependent kinase 22.7.11.220.440
4fv2EK5Mitogen-activated protein kinase 12.7.11.240.440
4g1wG1WMitogen-activated protein kinase 82.7.11.240.440
4utdACPAurora kinase A2.7.11.10.440
4v2gITCTetracycline repressor protein class D/0.440
4wsqKSAAP2-associated protein kinase 12.7.11.10.440
5dt4ATPAurora kinase A2.7.11.10.440