sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3o8a | O8A | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3o8a | O8A | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 1.000 | |
| 3qtr | X36 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.495 | |
| 2qpy | DHT | Androgen receptor | / | 0.493 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.492 | |
| 2ylo | TES | Androgen receptor | / | 0.491 | |
| 2pir | DHT | Androgen receptor | / | 0.490 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.490 | |
| 2ij7 | TPF | Mycocyclosin synthase | 1.14.21.9 | 0.489 | |
| 2bak | AQZ | Mitogen-activated protein kinase 14 | / | 0.488 | |
| 3i6r | J5Z | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.488 | |
| 4a9y | AQZ | Mitogen-activated protein kinase 14 | / | 0.488 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.487 | |
| 3d90 | NOG | Progesterone receptor | / | 0.487 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.486 | |
| 3vhu | SNL | Mineralocorticoid receptor | / | 0.486 | |
| 2piw | DHT | Androgen receptor | / | 0.485 | |
| 2acl | REA | Retinoic acid receptor RXR-alpha | / | 0.484 | |
| 3eel | 53T | Uncharacterized protein | / | 0.484 | |
| 4acm | 7YG | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.484 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.483 | |
| 2aax | PDN | Mineralocorticoid receptor | / | 0.483 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.483 | |
| 4f0e | 0RU | Poly [ADP-ribose] polymerase 15 | 2.4.2.30 | 0.483 | |
| 3uza | T4G | Adenosine receptor A2a | / | 0.483 | |
| 1e3k | R18 | Progesterone receptor | / | 0.481 | |
| 2pix | DHT | Androgen receptor | / | 0.481 | |
| 2ydi | YDI | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.480 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.480 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.480 | |
| 2pip | DHT | Androgen receptor | / | 0.479 | |
| 3qts | X46 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.479 | |
| 2oax | SNL | Mineralocorticoid receptor | / | 0.478 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.478 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.477 | |
| 1y9r | 1CA | Mineralocorticoid receptor | / | 0.477 | |
| 1ya3 | STR | Mineralocorticoid receptor | / | 0.477 | |
| 2wip | P49 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.477 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.477 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.477 | |
| 3sw4 | 18K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.477 | |
| 4xuh | SFI | Peroxisome proliferator-activated receptor gamma | / | 0.477 | |
| 4oea | DHT | Androgen receptor | / | 0.476 | |
| 4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.476 | |
| 2xgo | ZKD | Uncharacterized protein | / | 0.475 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 3d74 | NBB | Pheromone-binding protein ASP1 | / | 0.474 | |
| 4jlk | 1NO | Deoxycytidine kinase | 2.7.1.74 | 0.474 | |
| 4lsj | LSJ | Glucocorticoid receptor | / | 0.474 | |
| 1h1r | 6CP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.473 | |
| 1osv | CHC | Bile acid receptor | / | 0.473 | |
| 2piv | DHT | Androgen receptor | / | 0.473 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.473 | |
| 3b9l | AZZ | Serum albumin | / | 0.473 | |
| 3ua5 | 06X | Cytochrome P450 2B6 | 1.14.13 | 0.473 | |
| 3uli | 1N3 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.473 | |
| 3uxh | UXH | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.473 | |
| 4apu | OR8 | Progesterone receptor | / | 0.473 | |
| 4r3a | ANP | Blue-light-activated histidine kinase 2 | 2.7.13.3 | 0.473 | |
| 1xow | R18 | Androgen receptor | / | 0.472 | |
| 3d75 | NBB | Pheromone-binding protein ASP1 | / | 0.472 | |
| 3qly | 55V | Uncharacterized protein | / | 0.472 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 1qay | MEV | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.471 | |
| 2aqi | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.471 | |
| 2ejz | SAH | Diphthine synthase | / | 0.471 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.471 | |
| 3r8u | Z31 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.471 | |
| 4ftt | 6HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.471 | |
| 4gii | 0X6 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.471 | |
| 2ama | DHT | Androgen receptor | / | 0.470 | |
| 2ol4 | JPN | Enoyl-ACP reductase | / | 0.470 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.470 | |
| 3fnh | JPJ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.470 | |
| 3oia | A31 | Camphor 5-monooxygenase | 1.14.15.1 | 0.470 | |
| 3up0 | D7S | aceDAF-12 | / | 0.470 | |
| 4hyh | 1AM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.470 | |
| 1jtu | LYB | Thymidylate synthase | / | 0.469 | |
| 1ly4 | COQ | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 2op1 | 8PC | Enoyl-ACP reductase | / | 0.469 | |
| 3gcq | 1BU | Mitogen-activated protein kinase 14 | / | 0.469 | |
| 3o73 | O73 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.469 | |
| 4b8l | A0P | Aurora kinase B-A | 2.7.11.1 | 0.469 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.469 | |
| 1pox | FAD | Pyruvate oxidase | 1.2.3.3 | 0.468 | |
| 2aa5 | STR | Mineralocorticoid receptor | / | 0.468 | |
| 2amb | 17H | Androgen receptor | / | 0.468 | |
| 3cx5 | SMA | Cytochrome b | / | 0.468 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.468 | |
| 3p9t | TCL | Repressor | / | 0.468 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.468 | |
| 4ddr | MMV | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 4oha | HFT | Androgen receptor | / | 0.468 | |
| 1fdw | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.467 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.467 | |
| 1nbu | PH2 | Dihydroneopterin aldolase | / | 0.467 | |
| 1nhw | TCC | Enoyl-ACP reductase | / | 0.467 | |
| 1opb | RET | Retinol-binding protein 2 | / | 0.467 | |
| 3biz | 61E | Wee1-like protein kinase | 2.7.10.2 | 0.467 | |
| 3d5f | L41 | Peroxisome proliferator-activated receptor delta | / | 0.467 | |
| 3djf | BC3 | Purine nucleoside phosphorylase | / | 0.467 | |
| 3qtz | X42 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.467 | |
| 3vso | EK1 | Peroxisome proliferator-activated receptor gamma | / | 0.467 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.467 | |
| 5jad | FB2 | Platelet-activating factor acetylhydrolase | 3.1.1.47 | 0.467 | |
| 1nhg | TCL | Enoyl-ACP reductase | / | 0.466 | |
| 2brb | PFQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.466 | |
| 2xk4 | OL2 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.466 | |
| 3vqx | BLK | Pyrrolysine--tRNA ligase | / | 0.466 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.466 | |
| 4n3c | UD1 | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.466 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.466 | |
| 2qe4 | JJ3 | Estrogen receptor | / | 0.465 | |
| 2ylp | TES | Androgen receptor | / | 0.465 | |
| 3c6t | M14 | Gag-Pol polyprotein | 2.7.7.49 | 0.465 | |
| 3zra | ORB | Progesterone receptor | / | 0.465 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.465 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 2ayp | 43A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.464 | |
| 2w8y | NDR | Progesterone receptor | / | 0.464 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.464 | |
| 3ral | 04Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.464 | |
| 3uic | 09T | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.464 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.463 | |
| 2abi | 1CA | Mineralocorticoid receptor | / | 0.463 | |
| 2b52 | D42 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.463 | |
| 2cch | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.463 | |
| 2zb8 | IMN | Prostaglandin reductase 2 | 1.3.1.48 | 0.463 | |
| 3r9o | Z71 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.463 | |
| 4dit | 0KD | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.463 | |
| 4g20 | 484 | Vitamin D3 receptor A | / | 0.463 | |
| 4ogh | HFT | Androgen receptor | / | 0.463 | |
| 4zm6 | ACO | N-acetyl-beta-D glucosaminidase | / | 0.463 | |
| 5flj | QUE | Quercetinase QueD | / | 0.463 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.463 | |
| 1crb | RTL | Retinol-binding protein 1 | / | 0.462 | |
| 1daj | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 1wsv | THH | Aminomethyltransferase, mitochondrial | / | 0.462 | |
| 2bxm | IMN | Serum albumin | / | 0.462 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.462 | |
| 2ovh | AS0 | Progesterone receptor | / | 0.462 | |
| 2pkl | DHT | Androgen receptor | / | 0.462 | |
| 3zqt | TES | Androgen receptor | / | 0.462 | |
| 3zrb | ORC | Progesterone receptor | / | 0.462 | |
| 4xe6 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 1di8 | DTQ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.461 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1t7m | DHT | Androgen receptor | / | 0.461 | |
| 2i40 | BLZ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.461 | |
| 2ieb | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.461 | |
| 2tsc | CB3 | Thymidylate synthase | / | 0.461 | |
| 3cd2 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 3fc6 | REA | Retinoic acid receptor RXR-alpha | / | 0.461 | |
| 3iw1 | ASD | Steroid C26-monooxygenase | 1.14.13.141 | 0.461 | |
| 3oez | STI | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.461 | |
| 3rmf | 20Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.461 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.461 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.461 | |
| 4gih | 0X5 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.461 | |
| 4h4m | 494 | Gag-Pol polyprotein | 2.7.7.49 | 0.461 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.461 | |
| 1e3v | DXC | Steroid Delta-isomerase | 5.3.3.1 | 0.460 | |
| 1e7a | PFL | Serum albumin | / | 0.460 | |
| 1f4f | TP3 | Thymidylate synthase | / | 0.460 | |
| 1jg0 | DDT | Thymidylate synthase | / | 0.460 | |
| 1lwl | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 1p16 | GTP | mRNA-capping enzyme subunit alpha | 2.7.7.50 | 0.460 | |
| 1p93 | DEX | Glucocorticoid receptor | / | 0.460 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.460 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.460 | |
| 2i4z | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.460 | |
| 3qtw | X3A | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.460 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.460 | |
| 4eos | 1RO | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.460 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.459 | |
| 1eii | RTL | Retinol-binding protein 2 | / | 0.459 | |
| 2hko | FAD | Lysine-specific histone demethylase 1A | 1 | 0.459 | |
| 2i0z | FAD | NAD(FAD)-utilizing dehydrogenases | / | 0.459 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.459 | |
| 2ibz | SMA | Cytochrome b | / | 0.459 | |
| 2l98 | STL | Troponin C, slow skeletal and cardiac muscles | / | 0.459 | |
| 2oli | IOP | Basic phospholipase A2 VRV-PL-VIIIa | 3.1.1.4 | 0.459 | |
| 2ydo | ADN | Adenosine receptor A2a | / | 0.459 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.459 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.459 | |
| 3lkh | LT6 | Genome polyprotein | 2.7.7.48 | 0.459 | |
| 3lt2 | FT3 | Enoyl-ACP reductase | / | 0.459 | |
| 3owu | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.459 | |
| 3rai | X85 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.459 | |
| 3zew | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.459 | |
| 4fkr | 45K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.459 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.459 | |
| 4mf0 | 29Z | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.459 | |
| 4uda | DEX | Mineralocorticoid receptor | / | 0.459 | |
| 4yp7 | NAP | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.459 | |
| 5coq | TCU | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.459 | |
| 1ke5 | LS1 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.458 | |
| 1t73 | DHT | Androgen receptor | / | 0.458 | |
| 2ab2 | SNL | Mineralocorticoid receptor | / | 0.458 | |
| 2cgx | 3D3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.458 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.458 | |
| 2rc6 | NAP | Ferredoxin--NADP reductase | / | 0.458 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.458 | |
| 2w8y | 486 | Progesterone receptor | / | 0.458 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.458 | |
| 3dd1 | 25D | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.458 | |
| 4a2j | AS0 | Progesterone receptor | / | 0.458 | |
| 4ejh | 0QA | Cytochrome P450 2A13 | 1.14.14.1 | 0.458 | |
| 4eoi | 1RO | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.458 | |
| 1pd8 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 1uuo | BRF | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.457 | |
| 1x7r | GEN | Estrogen receptor | / | 0.457 | |
| 2b55 | D31 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.457 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.457 | |
| 2vss | ACO | Hydroxycinnamoyl-CoA hydratase-lyase | 4.1.2.41 | 0.457 | |
| 3cd3 | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.457 | |
| 3d77 | NBB | Pheromone-binding protein ASP1 | / | 0.457 | |
| 3fr0 | AJB | Glucokinase | 2.7.1.2 | 0.457 | |
| 4g67 | SAH | Uncharacterized ACR, COG1565 superfamily | / | 0.457 | |
| 4ise | 1FW | Glucokinase | 2.7.1.2 | 0.457 | |
| 4k7a | DHT | Androgen receptor | / | 0.457 | |
| 4nmd | FDA | Bifunctional protein PutA | / | 0.457 | |
| 4qzu | RTL | Retinol-binding protein 2 | / | 0.457 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.456 | |
| 1ly3 | COG | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1nde | MON | Estrogen receptor beta | / | 0.456 | |
| 1t63 | DHT | Androgen receptor | / | 0.456 | |
| 1xuo | LA1 | Integrin alpha-L | / | 0.456 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.456 | |
| 2bfa | CB3 | Pteridine reductase 1 | 1.5.1.33 | 0.456 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.456 | |
| 3gb4 | D3M | DdmC | / | 0.456 | |
| 3tjs | D0R | Cytochrome P450 3A4 | / | 0.456 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.456 | |
| 4da6 | GA2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.456 | |
| 4eqw | COA | Coenzyme A disulfide reductase | / | 0.456 | |
| 4h97 | 53S | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.456 | |
| 4mf1 | 29Y | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.456 | |
| 1dkf | BMS | Retinoic acid receptor alpha | / | 0.455 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 1s0x | C3S | Nuclear receptor ROR-alpha | / | 0.455 | |
| 1til | ATP | Anti-sigma F factor | / | 0.455 | |
| 1uh5 | TCL | Enoyl-ACP reductase | / | 0.455 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.455 | |
| 1vru | AAP | Gag-Pol polyprotein | 2.7.7.49 | 0.455 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.455 | |
| 2jj8 | AZZ | Deoxynucleoside kinase | / | 0.455 | |
| 2x6d | X6D | Aurora kinase A | 2.7.11.1 | 0.455 | |
| 2yhd | TES | Androgen receptor | / | 0.455 | |
| 3bqd | DAY | Glucocorticoid receptor | / | 0.455 | |
| 3ew2 | BTN | Hypothetical conserved protein | / | 0.455 | |
| 3pm1 | ET | HTH-type transcriptional regulator QacR | / | 0.455 | |
| 3saz | 043 | Malate synthase G | / | 0.455 | |
| 3td8 | D2R | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 3vru | YS3 | Vitamin D3 receptor | / | 0.455 | |
| 4eqs | COA | Coenzyme A disulfide reductase | / | 0.455 | |
| 4gh2 | HK0 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.455 | |
| 4jxx | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.455 | |
| 4okx | 198 | Androgen receptor | / | 0.455 | |
| 4qmp | DKI | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.455 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1ppj | ANY | Cytochrome b | / | 0.454 | |
| 1w0x | OLO | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 2dw4 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.454 | |
| 2pe2 | 464 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.454 | |
| 2piq | DHT | Androgen receptor | / | 0.454 | |
| 2vo7 | M05 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.454 | |
| 2wd9 | IBP | Acyl-coenzyme A synthetase ACSM2A, mitochondrial | 6.2.1.2 | 0.454 | |
| 2wpx | ACO | Orf14 | / | 0.454 | |
| 2xkf | BX1 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.454 | |
| 2yjx | YJX | Heat shock protein HSP 90-alpha | / | 0.454 | |
| 3hv3 | R49 | Mitogen-activated protein kinase 14 | / | 0.454 | |
| 3unj | 0BX | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.454 | |
| 3w8q | AGS | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.454 | |
| 4hyf | 1AK | Tankyrase-2 | 2.4.2.30 | 0.454 | |
| 4jd3 | COA | Alpha-pyrone synthesis polyketide synthase-like Pks11 | 2.3.1 | 0.454 | |
| 4ofu | DHT | Androgen receptor | / | 0.454 | |
| 5ex0 | SAH | Histone-lysine N-methyltransferase SMYD3 | 2.1.1.43 | 0.454 | |
| 1h1p | CMG | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 1j3k | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.453 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.453 | |
| 1zw1 | TN5 | Enoyl-ACP reductase | / | 0.453 | |
| 2aa7 | 1CA | Mineralocorticoid receptor | / | 0.453 | |
| 2ahv | COA | Acetate CoA-transferase YdiF | 2.8.3.8 | 0.453 | |
| 2ban | 357 | Gag-Pol polyprotein | 2.7.7.49 | 0.453 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.453 | |
| 2jds | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.453 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 3ang | DCC | Transcriptional repressor, TetR family | / | 0.453 | |
| 3h0a | 9RA | Retinoic acid receptor RXR-alpha | / | 0.453 | |
| 3ox3 | 4X4 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.453 | |
| 3q0g | BCO | Probable enoyl-CoA hydratase echA8 | 4.2.1.17 | 0.453 | |
| 3t2s | AGS | Heat shock protein HSP 90-alpha | / | 0.453 | |
| 4l9y | 1VU | L-malyl-CoA/beta-methylmalyl-CoA lyase | 4.1.3.24 | 0.453 | |
| 4rqk | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.453 | |
| 3vw7 | VPX | Proteinase-activated receptor 1 | / | 0.453 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.452 | |
| 1mvc | BM6 | Retinoic acid receptor RXR-alpha | / | 0.452 | |
| 1n4h | REA | Nuclear receptor ROR-beta | / | 0.452 | |
| 1pxx | DIF | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.452 | |
| 1uxj | NAD | Malate dehydrogenase | / | 0.452 | |
| 1zaf | 789 | Estrogen receptor beta | / | 0.452 | |
| 2dt5 | NAD | Redox-sensing transcriptional repressor Rex | / | 0.452 | |
| 2ivu | ZD6 | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.452 | |
| 2x1n | X1N | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.452 | |
| 3be2 | RAJ | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.452 | |
| 3gwn | FAD | Probable FAD-linked sulfhydryl oxidase R596 | 1.8.3.2 | 0.452 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.452 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.452 | |
| 3qlx | QLR | Uncharacterized protein | / | 0.452 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.452 | |
| 4ffl | ADP | Uncharacterized protein | / | 0.452 | |
| 4xwr | FAD | Cholesterol oxidase | 1.1.3.6 | 0.452 | |
| 4xx9 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.452 | |
| 5kf8 | ACO | Predicted acetyltransferase | / | 0.452 | |
| 1n4v | FAD | Cholesterol oxidase | 1.1.3.6 | 0.451 | |
| 1nhz | 486 | Glucocorticoid receptor | / | 0.451 | |
| 1q23 | FUA | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.451 | |
| 1t79 | DHT | Androgen receptor | / | 0.451 | |
| 1yqz | COA | Coenzyme A disulfide reductase | / | 0.451 | |
| 2fsz | OHT | Estrogen receptor beta | / | 0.451 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.451 | |
| 2hy8 | 1ST | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.451 | |
| 2pvn | P63 | Casein kinase II subunit alpha | 2.7.11.1 | 0.451 | |
| 2ykb | YKB | Heat shock protein HSP 90-alpha | / | 0.451 | |
| 3bfa | 9OD | Odorant binding protein ASP1 | / | 0.451 | |
| 3hbb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.451 | |
| 3i28 | 34N | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.451 | |
| 3ihg | VAK | Aklavinone 12-hydroxylase RdmE | / | 0.451 | |
| 3p6o | ETG | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.451 | |
| 4ftc | H6K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.451 | |
| 4fvr | ATP | Tyrosine-protein kinase JAK2 | / | 0.451 | |
| 4p6w | MOF | Glucocorticoid receptor | / | 0.451 | |
| 4qa2 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.451 | |
| 5akk | 1P8 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.451 | |
| 5koi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.451 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1hdr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.450 | |
| 1hpz | AAP | Gag-Pol polyprotein | 2.7.7.49 | 0.450 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 1y56 | FMN | Uncharacterized protein | / | 0.450 | |
| 1y56 | FMN | 382aa long hypothetical sarcosine oxidase | / | 0.450 | |
| 2brg | DFY | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.450 | |
| 2foi | JPA | Enoyl-acyl carrier reductase | / | 0.450 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 2xnm | WGZ | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.450 | |
| 3clb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.450 | |
| 3gi3 | B10 | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.450 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.450 | |
| 3iok | 1P6 | Tyrosine-protein kinase JAK2 | / | 0.450 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.450 | |
| 3l9n | L9N | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.450 | |
| 3lsy | FT0 | Enoyl-ACP reductase | / | 0.450 | |
| 3mne | DEX | Glucocorticoid receptor | / | 0.450 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3up3 | XCA | aceDAF-12 | / | 0.450 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 4i6f | 1C7 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.450 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.450 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 4oey | DHT | Androgen receptor | / | 0.450 | |
| 4ofr | DHT | Androgen receptor | / | 0.450 | |
| 4yfy | 1YJ | VioF | / | 0.450 | |
| 3pwh | ZMA | Adenosine receptor A2a | / | 0.450 | |
| 1jom | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1kyo | SMA | Cytochrome b | / | 0.449 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 2d3u | CCT | Polyprotein | / | 0.449 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 2o2s | TCL | Enoyl-acyl carrier reductase | / | 0.449 | |
| 2pit | DHT | Androgen receptor | / | 0.449 | |
| 2q2q | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.449 | |
| 2r3j | SCJ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.449 | |
| 2uzw | SS4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.449 | |
| 2wya | HMG | Hydroxymethylglutaryl-CoA synthase, mitochondrial | 2.3.3.10 | 0.449 | |
| 3elm | 24F | Collagenase 3 | 3.4.24 | 0.449 | |
| 3fnf | JPM | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 3ghv | GHC | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 3h6k | 33T | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.449 | |
| 3ix4 | TX1 | Transcriptional activator protein LasR | / | 0.449 | |
| 3mb6 | 01I | Casein kinase II subunit alpha | 2.7.11.1 | 0.449 | |
| 3p0f | BAU | Uridine phosphorylase 2 | 2.4.2.3 | 0.449 | |
| 3v49 | PK0 | Androgen receptor | / | 0.449 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.449 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.449 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.449 | |
| 4a4v | YFD | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 4a9e | 3PF | Bromodomain-containing protein 2 | / | 0.449 | |
| 4fhh | 0U3 | Vitamin D3 receptor A | / | 0.449 | |
| 4ft0 | HK9 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.449 | |
| 4u2s | FDA | Cholesterol oxidase | 1.1.3.6 | 0.449 | |
| 3rey | XAC | Adenosine receptor A2a | / | 0.449 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 1eet | BFU | Gag-Pol polyprotein | 2.7.7.49 | 0.448 | |
| 1ezv | SMA | Cytochrome b | / | 0.448 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.448 | |
| 1nv9 | SAH | Release factor glutamine methyltransferase | 2.1.1.297 | 0.448 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.448 | |
| 1sr7 | MOF | Progesterone receptor | / | 0.448 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 1xls | REA | Retinoic acid receptor RXR-alpha | / | 0.448 | |
| 2acl | L05 | Oxysterols receptor LXR-alpha | / | 0.448 | |
| 2cdz | 23D | Serine/threonine-protein kinase PAK 4 | 2.7.11.1 | 0.448 | |
| 2ic3 | HBY | Gag-Pol polyprotein | 2.7.7.49 | 0.448 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.448 | |
| 2nsd | 4PI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 2oh4 | GIG | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.448 | |
| 2ops | HBQ | Gag-Pol polyprotein | 2.7.7.49 | 0.448 | |
| 2p1v | 5TN | Retinoic acid receptor RXR-alpha | / | 0.448 | |
| 2vv9 | IM9 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 2xch | CKG | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.448 | |
| 2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 | 0.448 | |
| 3bpt | QUE | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial | 3.1.2.4 | 0.448 | |
| 3l9m | L9M | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.448 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.448 | |
| 3nrc | TCL | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.448 | |
| 3pgh | FLP | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.448 | |
| 3tkh | 07S | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
| 3zrb | OR8 | Progesterone receptor | / | 0.448 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.448 | |
| 4b1f | KRH | Glutamate racemase | / | 0.448 | |
| 4b5n | FMN | NAD(P)H:flavin oxidoreductase Sye4 | / | 0.448 | |
| 4c9p | CAM | Cytochrome P450 | / | 0.448 | |
| 4dm6 | TTB | Retinoic acid receptor beta | / | 0.448 | |
| 4f08 | 1RS | Tyrosine-protein kinase JAK2 | / | 0.448 | |
| 4hy6 | FJ1 | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 4wa9 | AXI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.448 | |
| 4z1f | H71 | Heat shock protein 75 kDa, mitochondrial | / | 0.448 | |
| 5kf1 | ACO | Predicted acetyltransferase | / | 0.448 | |
| 1cs4 | FOK | Adenylate cyclase type 2 | / | 0.447 | |
| 1cs4 | FOK | Adenylate cyclase type 5 | / | 0.447 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.447 | |
| 1sg9 | SAM | Release factor glutamine methyltransferase | 2.1.1.297 | 0.447 | |
| 2a3i | C0R | Mineralocorticoid receptor | / | 0.447 | |
| 2g2f | AGS | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.447 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.447 | |
| 2kce | D16 | Thymidylate synthase | / | 0.447 | |
| 2nmt | NHM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.447 | |
| 2ojf | 4PY | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.447 | |
| 2vq5 | LDP | S-norcoclaurine synthase | / | 0.447 | |
| 2w1h | L0F | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 3bfb | 9OD | Pheromone-binding protein ASP1 | / | 0.447 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.447 | |
| 3dol | GWI | Pol protein | / | 0.447 | |
| 3mtl | FEF | Cyclin-dependent kinase 16 | 2.7.11.22 | 0.447 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.447 | |
| 3qtu | X44 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.447 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.447 | |
| 4aoi | 4K0 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.447 | |
| 4bcp | T3C | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 4cax | MYA | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.447 | |
| 4egn | TWO | Cytochrome P450 | / | 0.447 | |
| 4fkt | 48K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 4ftr | 5HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 4fvq | ATP | Tyrosine-protein kinase JAK2 | / | 0.447 | |
| 4kko | 1RE | Gag-Pol polyprotein | 2.7.7.49 | 0.447 | |
| 4u9a | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.447 | |
| 1eny | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 1xj7 | DHT | Androgen receptor | / | 0.446 | |
| 1xp6 | AIU | Estrogen receptor | / | 0.446 | |
| 2aa6 | STR | Mineralocorticoid receptor | / | 0.446 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.446 | |
| 2pui | ADP | Methylthioribose kinase | 2.7.1.100 | 0.446 | |
| 2vzm | NRB | Cytochrome P450 monooxygenase PikC | / | 0.446 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.446 | |
| 2x7g | PVB | SRSF protein kinase 2 | 2.7.11.1 | 0.446 | |
| 3cse | N22 | Uncharacterized protein | / | 0.446 | |
| 3dr1 | C5D | Vitamin D3 receptor A | / | 0.446 | |
| 3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3f4b | TCL | Enoyl-acyl carrier protein reductase | / | 0.446 | |
| 3ft8 | MOJ | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 3gds | VAL_TYR_TYR_PHE | Serine endoprotease DegS | 3.4.21.107 | 0.446 | |
| 3irn | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.446 | |
| 3qpv | ADP | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 | 2.7.1.105 | 0.446 | |
| 3qqk | X02 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 3r8v | Z62 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 3t19 | 5MA | Gag-Pol polyprotein | 2.7.7.49 | 0.446 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.446 | |
| 4apu | A2K | Progesterone receptor | / | 0.446 | |
| 4e37 | NDP | Catalase | 1.11.1.6 | 0.446 | |
| 4fkw | 62K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 4fsw | HK6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.446 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.446 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.446 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.446 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 4uaj | FAD | Na(+)-translocating NADH-quinone reductase subunit F | / | 0.446 | |
| 5fsx | ADP | Uncharacterized protein | / | 0.446 | |
| 5htx | ADP | Putative xylulose kinase | / | 0.446 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.446 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.446 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 1dub | CAA | Enoyl-CoA hydratase, mitochondrial | 4.2.1.17 | 0.445 | |
| 1s9q | OHT | Estrogen-related receptor gamma | / | 0.445 | |
| 1v1k | 3FP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 1z5a | ADP | Type 2 DNA topoisomerase 6 subunit B | / | 0.445 | |
| 1ztq | 033 | Collagenase 3 | 3.4.24 | 0.445 | |
| 2bxq | IMN | Serum albumin | / | 0.445 | |
| 2cgu | 3A3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 2fb8 | 215 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.445 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.445 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.445 | |
| 2p2h | 994 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.445 | |
| 2vdv | SAM | tRNA (guanine-N(7)-)-methyltransferase | / | 0.445 | |
| 2x2k | X2K | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.445 | |
| 2z4b | DC8 | Estrogen receptor beta | / | 0.445 | |
| 2zce | PYL | Pyrrolysine--tRNA ligase | / | 0.445 | |
| 3d73 | NBB | Pheromone-binding protein ASP1 | / | 0.445 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.445 | |
| 3er9 | 3AT | Poly(A) polymerase catalytic subunit | 2.7.7.19 | 0.445 | |
| 3ezv | EZV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 3ha7 | B32 | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.445 | |
| 3hcr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.445 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.445 | |
| 3nhy | A7B | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.445 | |
| 3tnw | F18 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 3v1m | HPK | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase | 3.7.1.8 | 0.445 | |
| 3v8t | 477 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.445 | |
| 3w5q | 3KL | Vitamin D3 receptor | / | 0.445 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 4dvi | 2IW | Tankyrase-1 | 2.4.2.30 | 0.445 | |
| 4iwq | 1FV | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.445 | |
| 4oil | HFT | Androgen receptor | / | 0.445 | |
| 4rqu | NAD | Alcohol dehydrogenase class-P | / | 0.445 | |
| 1cbq | RE9 | Cellular retinoic acid-binding protein 2 | / | 0.444 | |
| 1hnv | TBO | Gag-Pol polyprotein | 2.7.7.49 | 0.444 | |
| 1uy9 | PU6 | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 1vrw | NAI | Enoyl-ACP reductase | / | 0.444 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2c3l | IDZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 2iws | NP4 | ATP-dependent molecular chaperone HSP82 | / | 0.444 | |
| 2pio | DHT | Androgen receptor | / | 0.444 | |
| 2rbe | ZMG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.444 | |
| 2rm2 | W43 | Genome polyprotein | / | 0.444 | |
| 2ynh | EUR | Gag-Pol polyprotein | 2.7.7.49 | 0.444 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.444 | |
| 3jpu | TY4 | Transcriptional activator protein LasR | / | 0.444 | |
| 3lak | KR1 | Gag-Pol polyprotein | 2.7.7.49 | 0.444 | |
| 3lfm | 3DT | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.444 | |
| 3vrv | YSD | Vitamin D3 receptor | / | 0.444 | |
| 4a9m | P9M | Bromodomain-containing protein 2 | / | 0.444 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 4h6z | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.444 | |
| 4ivb | 1J5 | Tyrosine-protein kinase JAK1 | / | 0.444 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.444 | |
| 4nbb | 9CA | Terminal oxygenase component of carbazole | / | 0.444 | |
| 4zzj | CNA | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.444 | |
| 5dp2 | NAP | CurF | / | 0.444 | |
| 5e8x | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.444 | |
| 5h86 | BCO | Histone acetyltransferase KAT2A | 2.3.1.48 | 0.444 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.444 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.444 | |
| 1cjk | FOK | Adenylate cyclase type 2 | / | 0.443 | |
| 1cjk | FOK | Adenylate cyclase type 5 | / | 0.443 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 1j9z | FAD | NADPH--cytochrome P450 reductase | / | 0.443 | |
| 1r0e | DFN | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.443 | |
| 1uhh | CZP | Aequorin-2 | / | 0.443 | |
| 2e9o | A58 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.443 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.443 | |
| 2r6h | FAD | Na(+)-translocating NADH-quinone reductase subunit F | / | 0.443 | |
| 2r7b | 253 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.443 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.443 | |
| 3cbs | R12 | Cellular retinoic acid-binding protein 2 | / | 0.443 | |
| 3q0z | 23E | Genome polyprotein | 2.7.7.48 | 0.443 | |
| 3qtx | X43 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 3w0i | O11 | Vitamin D3 receptor | / | 0.443 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.443 | |
| 4a95 | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.443 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 4dgo | 0JW | Casein kinase II subunit alpha | 2.7.11.1 | 0.443 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.443 | |
| 4juf | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.443 | |
| 4lb2 | DM5 | Serum albumin | / | 0.443 | |
| 4oew | 5IO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.443 | |
| 4okb | 198 | Androgen receptor | / | 0.443 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.443 | |
| 4qa0 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.443 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.443 | |
| 5cb3 | APR | O-acetyl-ADP-ribose deacetylase | / | 0.443 | |
| 5cp8 | TCU | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 5hbs | RTL | Retinol-binding protein 1 | / | 0.443 | |
| 5hes | 032 | Mitogen-activated protein kinase kinase kinase 20 | 2.7.11.25 | 0.443 | |
| 5l7d | CLR | Smoothened homolog | / | 0.443 | |
| 1a80 | NDP | 2,5-diketo-D-gluconic acid reductase A | 1.1.1.346 | 0.442 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1ci7 | CB3 | Thymidylate synthase | 2.1.1.45 | 0.442 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 1ek2 | CDU | Bifunctional epoxide hydrolase 2 | / | 0.442 | |
| 1k6m | AGS | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 | 2.7.1.105 | 0.442 | |
| 1kqw | RTL | Cellular retinol-binding protein type II | / | 0.442 | |
| 1nvq | UCN | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.442 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.442 | |
| 1uog | P1C | Deacetoxycephalosporin C synthase | 1.14.20.1 | 0.442 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.442 | |
| 2eft | COA | 3-oxoacyl-[acyl-carrier-protein] synthase 3 | / | 0.442 | |
| 2flh | ZEA | Cytokinin-specific binding protein | / | 0.442 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.442 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.442 | |
| 2ix5 | FAD | Acyl-coenzyme A oxidase 4, peroxisomal | 1.3.3.6 | 0.442 | |
| 2o4j | VD4 | Vitamin D3 receptor | / | 0.442 | |
| 2q7l | TES | Androgen receptor | / | 0.442 | |
| 2qmz | LDP | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.442 | |
| 2z4y | 252 | Geranylgeranyl pyrophosphate synthase | / | 0.442 | |
| 3anx | MTA | Polyamine aminopropyltransferase | / | 0.442 | |
| 3dnd | LL2 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.442 | |
| 3eej | 53R | Uncharacterized protein | / | 0.442 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.442 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.442 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 3zk6 | H1I | Bcl-2-like protein 1 | / | 0.442 | |
| 4agu | D15 | Cyclin-dependent kinase-like 1 | / | 0.442 | |
| 4dz5 | NAP | Aldo-keto reductase family 1 member C3 | / | 0.442 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 4kug | NAD | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.442 | |
| 4kuh | CAA | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.442 | |
| 4pkl | 1GH | Uncharacterized protein | / | 0.442 | |
| 4rqv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.442 | |
| 5iub | CLR | Adenosine receptor A2a | / | 0.442 | |
| 5kf2 | ACO | Predicted acetyltransferase | / | 0.442 | |
| 5kgp | ACO | Predicted acetyltransferase | / | 0.442 | |
| 1gs4 | ZK5 | Androgen receptor | / | 0.441 | |
| 1ikw | EFZ | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 1jla | TNK | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 1mab | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.441 | |
| 1ml6 | GBX | Glutathione S-transferase A2 | 2.5.1.18 | 0.441 | |
| 1mxt | FAE | Cholesterol oxidase | 1.1.3.6 | 0.441 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.441 | |
| 1s4d | SAH | Uroporphyrinogen-III C-methyltransferase | 2.1.1.107 | 0.441 | |
| 1t7r | DHT | Androgen receptor | / | 0.441 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.441 | |
| 1u3s | 797 | Estrogen receptor beta | / | 0.441 | |
| 1v79 | FR7 | Adenosine deaminase | 3.5.4.4 | 0.441 | |
| 1z95 | 198 | Androgen receptor | / | 0.441 | |
| 2bbq | PFG | Thymidylate synthase | / | 0.441 | |
| 2gpj | FAD | Siderophore-interacting protein | / | 0.441 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.441 | |
| 2pog | WST | Estrogen receptor | / | 0.441 | |
| 2q5o | PPY | Indole-3-pyruvate decarboxylase | 4.1.1.74 | 0.441 | |
| 2q61 | SF1 | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 2rki | TT1 | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 2x8i | X8I | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 3i1y | 33N | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.441 | |
| 3ipt | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.441 | |
| 3nxv | D2F | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 3ox2 | 79X | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.441 | |
| 3rvg | 17P | Tyrosine-protein kinase JAK2 | / | 0.441 | |
| 3s1h | 56Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3zc5 | W9Z | Hepatocyte growth factor receptor | 2.7.10.1 | 0.441 | |
| 4a31 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.441 | |
| 4eh9 | IRG | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 4eil | UMP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.441 | |
| 4isf | 1FX | Glucokinase | 2.7.1.2 | 0.441 | |
| 4rrg | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.441 | |
| 5fwn | NAP | Putative dehydrogenase | / | 0.441 | |
| 1b48 | HAG | Glutathione S-transferase A4 | 2.5.1.18 | 0.440 | |
| 1cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1e3g | R18 | Androgen receptor | / | 0.440 | |
| 1gs3 | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.440 | |
| 1i2l | DCS | Aminodeoxychorismate lyase | 4.1.3.38 | 0.440 | |
| 1juv | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1ke9 | LS5 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 1l2j | ETC | Estrogen receptor beta | / | 0.440 | |
| 1pkd | UCN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 1tkz | H16 | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 1trg | CB3 | Thymidylate synthase | / | 0.440 | |
| 1x7j | GEN | Estrogen receptor beta | / | 0.440 | |
| 2am9 | TES | Androgen receptor | / | 0.440 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.440 | |
| 2c6o | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 2ovm | AS0 | Progesterone receptor | / | 0.440 | |
| 2owb | 626 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.440 | |
| 2p1o | NLA | Protein TRANSPORT INHIBITOR RESPONSE 1 | / | 0.440 | |
| 2r4u | ADP | Glycogen synthase | 2.4.1.21 | 0.440 | |
| 2wms | ZYS | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 2xk6 | EQH | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.440 | |
| 2ym6 | YM6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 2z50 | 028 | Geranylgeranyl pyrophosphate synthase | / | 0.440 | |
| 3d78 | NBB | Pheromone-binding protein ASP1 | / | 0.440 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.440 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.440 | |
| 3kyt | HC2 | Nuclear receptor ROR-gamma | / | 0.440 | |
| 3ox4 | NAD | Alcohol dehydrogenase 2 | 1.1.1.1 | 0.440 | |
| 3qwi | CUE | 17beta-hydroxysteroid dehydrogenase | / | 0.440 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.440 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.440 | |
| 3u8k | 09P | Acetylcholine-binding protein | / | 0.440 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.440 | |
| 3zvm | ADP | Bifunctional polynucleotide phosphatase/kinase | 2.7.1.78 | 0.440 | |
| 4a33 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.440 | |
| 4au8 | Z3R | Cyclin-dependent-like kinase 5 | 2.7.11.1 | 0.440 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.440 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 4bjx | 73B | Bromodomain-containing protein 4 | / | 0.440 | |
| 4c62 | XWW | Tyrosine-protein kinase JAK2 | / | 0.440 | |
| 4ck2 | NVU | Integrase | / | 0.440 | |
| 4da8 | BG2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.440 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 4fsr | HKC | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 4iv4 | 1GS | Estrogen receptor | / | 0.440 | |
| 5aab | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.440 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.440 |