sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2yat | EEU | Estrogen receptor |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2yat | EEU | Estrogen receptor | / | 1.000 | |
| 2p15 | EZT | Estrogen receptor | / | 0.577 | |
| 1zky | 689 | Estrogen receptor | / | 0.536 | |
| 1gwr | EST | Estrogen receptor | / | 0.527 | |
| 5hyr | EST | Estrogen receptor | / | 0.525 | |
| 3oll | EST | Estrogen receptor beta | / | 0.524 | |
| 2fai | 459 | Estrogen receptor | / | 0.523 | |
| 3l03 | 4OH | Estrogen receptor | / | 0.522 | |
| 2pnu | ENM | Androgen receptor | / | 0.520 | |
| 3q95 | ESL | Estrogen receptor | / | 0.517 | |
| 2b1z | 17M | Estrogen receptor | / | 0.516 | |
| 3uud | EST | Estrogen receptor | / | 0.515 | |
| 1g50 | EST | Estrogen receptor | / | 0.513 | |
| 5dxg | EST | Estrogen receptor | / | 0.511 | |
| 2g44 | T3O | Estrogen receptor | / | 0.509 | |
| 4j24 | EST | Estrogen receptor beta | / | 0.509 | |
| 1l2j | ETC | Estrogen receptor beta | / | 0.507 | |
| 2pog | WST | Estrogen receptor | / | 0.506 | |
| 1x7j | GEN | Estrogen receptor beta | / | 0.505 | |
| 1l2i | ETC | Estrogen receptor | / | 0.504 | |
| 2j7y | E3O | Estrogen receptor beta | / | 0.504 | |
| 1x7r | GEN | Estrogen receptor | / | 0.501 | |
| 4j26 | EST | Estrogen receptor beta | / | 0.501 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.500 | |
| 4iw8 | KN3 | Estrogen receptor | / | 0.500 | |
| 4lsj | LSJ | Glucocorticoid receptor | / | 0.500 | |
| 2bla | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.499 | |
| 3kjs | DQ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.498 | |
| 4kbn | 25U | Dihydrofolate reductase | 1.5.1.3 | 0.498 | |
| 1og5 | SWF | Cytochrome P450 2C9 | / | 0.497 | |
| 2xvv | 9DN | Serum albumin | / | 0.497 | |
| 3um5 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.497 | |
| 3um6 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.497 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.495 | |
| 4pxm | EST | Estrogen receptor | / | 0.495 | |
| 5dx3 | EST | Estrogen receptor | / | 0.495 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.494 | |
| 1x7e | 244 | Estrogen receptor | / | 0.493 | |
| 2q70 | DC8 | Estrogen receptor | / | 0.493 | |
| 4iv2 | 1GR | Estrogen receptor | / | 0.493 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.493 | |
| 1j3j | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.492 | |
| 3ols | EST | Estrogen receptor beta | / | 0.492 | |
| 1j3k | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.491 | |
| 3eon | 341 | Glutaryl-CoA dehydrogenase | / | 0.491 | |
| 4bhw | 01K | Histone acetyltransferase p300 | / | 0.491 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.490 | |
| 2jj3 | JJ3 | Estrogen receptor beta | / | 0.490 | |
| 2w3a | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.490 | |
| 3qg2 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.490 | |
| 4kak | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.490 | |
| 3qak | UKA | Adenosine receptor A2a | / | 0.490 | |
| 4y1b | NAP | AntE | / | 0.489 | |
| 1vj3 | TAB | Dihydrofolate reductase | 1.5.1.3 | 0.488 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.488 | |
| 2yja | EST | Estrogen receptor | / | 0.487 | |
| 3nxv | D2F | Dihydrofolate reductase | 1.5.1.3 | 0.487 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.486 | |
| 1gwq | ZTW | Estrogen receptor | / | 0.485 | |
| 1xp9 | AIJ | Estrogen receptor | / | 0.485 | |
| 3qgt | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.485 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.485 | |
| 4dsb | A8S | Abscisic acid receptor PYL3 | / | 0.485 | |
| 4std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.485 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.484 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.484 | |
| 1daj | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.483 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.483 | |
| 3iro | 2CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.483 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.483 | |
| 4ixc | 1JD | Glucokinase | 2.7.1.2 | 0.483 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.482 | |
| 2vss | ACO | Hydroxycinnamoyl-CoA hydratase-lyase | 4.1.2.41 | 0.482 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.482 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.482 | |
| 3reo | EUG | (Iso)eugenol O-methyltransferase | 2.1.1.146 | 0.482 | |
| 4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.482 | |
| 5ify | UMP | Glucose-1-phosphate thymidylyltransferase | / | 0.482 | |
| 1lhu | EST | Sex hormone-binding globulin | / | 0.481 | |
| 1zaf | 789 | Estrogen receptor beta | / | 0.481 | |
| 2nv7 | 555 | Estrogen receptor beta | / | 0.481 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.481 | |
| 4iwv | 1J9 | Glucokinase | 2.7.1.2 | 0.481 | |
| 5ai5 | BSU | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.481 | |
| 2qa8 | GEN | Estrogen receptor | / | 0.480 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.480 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.480 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.480 | |
| 4a2j | AS0 | Progesterone receptor | / | 0.480 | |
| 4zn7 | DES | Estrogen receptor | / | 0.480 | |
| 1x78 | 244 | Estrogen receptor beta | / | 0.479 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.479 | |
| 4pp6 | STL | Estrogen receptor | / | 0.479 | |
| 5cc9 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.479 | |
| 1aoe | GW3 | Dihydrofolate reductase | 1.5.1.3 | 0.478 | |
| 1t13 | INI | 6,7-dimethyl-8-ribityllumazine synthase 2 | / | 0.478 | |
| 2ban | 357 | Gag-Pol polyprotein | 2.7.7.49 | 0.478 | |
| 3tky | N7I | (Iso)eugenol O-methyltransferase | 2.1.1.146 | 0.478 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.478 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.478 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.478 | |
| 4ivy | 1GT | Estrogen receptor | / | 0.478 | |
| 4mv1 | ADP | Biotin carboxylase | 6.3.4.14 | 0.478 | |
| 4yfy | 1YJ | VioF | / | 0.478 | |
| 1qkm | GEN | Estrogen receptor beta | / | 0.477 | |
| 1ro9 | 8BR | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.477 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.477 | |
| 1u9e | 397 | Estrogen receptor beta | / | 0.477 | |
| 2bxq | IMN | Serum albumin | / | 0.477 | |
| 2oax | SNL | Mineralocorticoid receptor | / | 0.477 | |
| 2p1u | 4TN | Retinoic acid receptor RXR-alpha | / | 0.477 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.477 | |
| 3hf6 | LX0 | Tryptophan 5-hydroxylase 1 | 1.14.16.4 | 0.477 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.477 | |
| 4ap1 | NAP | Steroid monooxygenase | / | 0.477 | |
| 4dsc | A8S | Abscisic acid receptor PYL3 | / | 0.477 | |
| 4lg5 | A1O | Abscisic acid receptor PYL2 | / | 0.477 | |
| 4qbh | AP5 | Adenylate kinase | / | 0.477 | |
| 5d7p | AR6 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.477 | |
| 1nhz | 486 | Glucocorticoid receptor | / | 0.476 | |
| 2b01 | TUD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.476 | |
| 2ocf | EST | Estrogen receptor | / | 0.476 | |
| 3cd2 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
| 3k47 | D09 | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
| 4yfy | 0FX | VioF | / | 0.476 | |
| 1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.475 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.475 | |
| 2bl9 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.475 | |
| 2fzj | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.475 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.475 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.475 | |
| 4kfj | 1R0 | Dihydrofolate reductase | 1.5.1.3 | 0.475 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.475 | |
| 1fdw | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.474 | |
| 1sd1 | FMC | S-methyl-5'-thioadenosine phosphorylase | / | 0.474 | |
| 3bfb | 9OD | Pheromone-binding protein ASP1 | / | 0.474 | |
| 3erd | DES | Estrogen receptor | / | 0.474 | |
| 3ngl | NAP | Bifunctional protein FolD | / | 0.474 | |
| 4ixf | IXF | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 4kd7 | 9DR | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 4o71 | CPB | Bromodomain-containing protein 4 | / | 0.474 | |
| 4zhi | ADP | Kinesin-like protein KIF11 | / | 0.474 | |
| 1ia1 | TQ3 | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.473 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.473 | |
| 2a4x | BLM | Mitomycin-binding protein | / | 0.473 | |
| 2b03 | TUD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.473 | |
| 2bf7 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.473 | |
| 3irn | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.473 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.473 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.473 | |
| 3s41 | S41 | Glucokinase | 2.7.1.2 | 0.473 | |
| 4egn | TWO | Cytochrome P450 | / | 0.473 | |
| 4h96 | 14Q | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 4m6l | 21V | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 1e26 | GPB | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 1jf2 | CZH | Obelin | / | 0.472 | |
| 1s3v | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 2blb | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.472 | |
| 2j7x | EST | Estrogen receptor beta | / | 0.472 | |
| 3nxy | D2H | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.472 | |
| 1yy4 | 4NA | Estrogen receptor beta | / | 0.471 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.471 | |
| 3koo | 24D | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.471 | |
| 3qly | 55V | Uncharacterized protein | / | 0.471 | |
| 5kf9 | ACO | Predicted acetyltransferase | / | 0.471 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 1eii | RTL | Retinol-binding protein 2 | / | 0.470 | |
| 1j3i | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.470 | |
| 1pq6 | 965 | Oxysterols receptor LXR-beta | / | 0.470 | |
| 1xpc | AIT | Estrogen receptor | / | 0.470 | |
| 2imk | GTX | AGAP009194-PA | / | 0.470 | |
| 3clb | TMQ | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.470 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.470 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.470 | |
| 1wxy | FRK | Adenosine deaminase | 3.5.4.4 | 0.469 | |
| 2amb | 17H | Androgen receptor | / | 0.469 | |
| 2blc | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.469 | |
| 3ozc | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.469 | |
| 4jda | A9S | Abscisic acid receptor PYL3 | / | 0.469 | |
| 4k6i | 9RA | Retinoic acid receptor RXR-alpha | / | 0.469 | |
| 1k74 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.468 | |
| 1lhw | ESM | Sex hormone-binding globulin | / | 0.468 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.468 | |
| 1rf9 | DBR | Camphor 5-monooxygenase | 1.14.15.1 | 0.468 | |
| 2ylo | TES | Androgen receptor | / | 0.468 | |
| 3htj | ET | EbrA repressor | / | 0.468 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.468 | |
| 4ag7 | COA | Glucosamine 6-phosphate N-acetyltransferase | / | 0.468 | |
| 4dma | 0L8 | Estrogen receptor | / | 0.468 | |
| 4ib4 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.468 | |
| 4ixe | IXE | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.468 | |
| 4jq3 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.468 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.468 | |
| 1olm | VTQ | SEC14-like protein 2 | / | 0.467 | |
| 2p1v | 5TN | Retinoic acid receptor RXR-alpha | / | 0.467 | |
| 3v1m | HPK | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase | 3.7.1.8 | 0.467 | |
| 4gi2 | NAP | Crotonyl-CoA carboxylase/reductase | / | 0.467 | |
| 4h1j | 0YH | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.467 | |
| 4h97 | 53S | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.467 | |
| 4je5 | PLP | Aromatic/aminoadipate aminotransferase 1 | 2.6.1.39 | 0.467 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.466 | |
| 1e3k | R18 | Progesterone receptor | / | 0.466 | |
| 1ej3 | CZH | Aequorin-2 | / | 0.466 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.466 | |
| 1kdm | DHT | Sex hormone-binding globulin | / | 0.466 | |
| 1pz1 | NAP | General stress protein 69 | / | 0.466 | |
| 1q6t | 600 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.466 | |
| 1rdt | L79 | Retinoic acid receptor RXR-alpha | / | 0.466 | |
| 1yye | 196 | Estrogen receptor beta | / | 0.466 | |
| 2b00 | GCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.466 | |
| 2w8y | 486 | Progesterone receptor | / | 0.466 | |
| 3gcq | 1BU | Mitogen-activated protein kinase 14 | / | 0.466 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.466 | |
| 3nmh | PYV | Abscisic acid receptor PYL2 | / | 0.466 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.466 | |
| 4bqu | CLR | Japanin | / | 0.466 | |
| 4bri | UNP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.466 | |
| 4qii | 2NE | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.466 | |
| 5kf8 | ACO | Predicted acetyltransferase | / | 0.466 | |
| 1equ | EQI | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.465 | |
| 1uhh | CZP | Aequorin-2 | / | 0.465 | |
| 1xdu | SFG | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.465 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.465 | |
| 2fzh | DH1 | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 3cyz | 9OD | Pheromone-binding protein ASP1 | / | 0.465 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.465 | |
| 3lfc | Z86 | Mitogen-activated protein kinase 14 | / | 0.465 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.465 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.465 | |
| 4eil | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.465 | |
| 4g8z | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 4iui | 1GQ | Estrogen receptor | / | 0.465 | |
| 4iwf | 15Q | Estrogen receptor | / | 0.465 | |
| 5kgp | ACO | Predicted acetyltransferase | / | 0.465 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 1ly4 | COQ | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 1n71 | COA | Aac(6')-Ii protein | / | 0.464 | |
| 2bel | CBO | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.464 | |
| 2pui | ADP | Methylthioribose kinase | 2.7.1.100 | 0.464 | |
| 2x1z | PID | Peridinin-chlorophyll a-binding protein 1, chloroplastic | / | 0.464 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.464 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.464 | |
| 3um8 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.464 | |
| 3wd9 | QPC | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.464 | |
| 4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.464 | |
| 4hqv | QEI | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.464 | |
| 4l23 | X6K | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | / | 0.464 | |
| 1boz | PRD | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 2g5o | DRQ | Estrogen receptor | / | 0.463 | |
| 2oci | TYC | Valacyclovir hydrolase | 3.1 | 0.463 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.463 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.463 | |
| 3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.463 | |
| 3jsu | KA5 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.463 | |
| 3l3r | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 3nef | PYV | Abscisic acid receptor PYL1 | / | 0.463 | |
| 3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.463 | |
| 3sl6 | JN8 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.463 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.463 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.463 | |
| 4pzt | SOP | Histone acetyltransferase p300 | / | 0.463 | |
| 4qij | 1HA | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.463 | |
| 1dtn | APG | Mandelate racemase | / | 0.462 | |
| 1klk | PMD | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.462 | |
| 1x7b | 041 | Estrogen receptor beta | / | 0.462 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.462 | |
| 3dr1 | C5D | Vitamin D3 receptor A | / | 0.462 | |
| 3nxo | D2B | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 3vjh | J35 | Peroxisome proliferator-activated receptor gamma | / | 0.462 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.462 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.462 | |
| 4j7x | SAS | Sepiapterin reductase | 1.1.1.153 | 0.462 | |
| 4jx1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.462 | |
| 4tmc | FMN | Old yellow enzyme | / | 0.462 | |
| 5d7q | 4I5 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.462 | |
| 1cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.461 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.461 | |
| 2azy | CHD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.461 | |
| 2i1v | ADP | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 | 2.7.1.105 | 0.461 | |
| 2imf | TOM | 2-hydroxychromene-2-carboxylate isomerase | 5.99.1.4 | 0.461 | |
| 2on6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.461 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.461 | |
| 3qfx | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.461 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.461 | |
| 3zhq | TPP | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.461 | |
| 4bfy | ZVY | Pantothenate kinase | 2.7.1.33 | 0.461 | |
| 4c3y | ANB | 3-ketosteroid dehydrogenase | / | 0.461 | |
| 4ds8 | A8S | Abscisic acid receptor PYL3 | / | 0.461 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.461 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.461 | |
| 5ccc | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1crb | RTL | Retinol-binding protein 1 | / | 0.460 | |
| 1e7a | PFL | Serum albumin | / | 0.460 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.460 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 1qv1 | CZH | Obelin | / | 0.460 | |
| 1sr7 | MOF | Progesterone receptor | / | 0.460 | |
| 1v35 | NAI | Enoyl-ACP reductase | / | 0.460 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.460 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.460 | |
| 2fb8 | 215 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.460 | |
| 2pkl | DHT | Androgen receptor | / | 0.460 | |
| 2wue | KEK | 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase | 3.7.1.17 | 0.460 | |
| 2y46 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.460 | |
| 2z7g | EH9 | Adenosine deaminase | 3.5.4.4 | 0.460 | |
| 3ans | S38 | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.460 | |
| 3dhb | C6L | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.460 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.460 | |
| 4e0u | 0MV | Cyclic dipeptide N-prenyltransferase | / | 0.460 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.460 | |
| 4nhy | PD2 | Prolyl 3-hydroxylase OGFOD1 | 1.14.11 | 0.460 | |
| 4nqg | CZH | Mitrocomin | / | 0.460 | |
| 5ab7 | MLC | Nonspecific lipid-transfer protein, putative | / | 0.460 | |
| 1a4i | NDP | C-1-tetrahydrofolate synthase, cytoplasmic | 1.5.1.5 | 0.459 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.459 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.459 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.459 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.459 | |
| 1x76 | 697 | Estrogen receptor beta | / | 0.459 | |
| 2xw7 | NDP | Dihydrofolate reductase | / | 0.459 | |
| 3d5f | L41 | Peroxisome proliferator-activated receptor delta | / | 0.459 | |
| 3dha | C6L | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.459 | |
| 3p9t | TCL | Repressor | / | 0.459 | |
| 4ejh | 0QA | Cytochrome P450 2A13 | 1.14.14.1 | 0.459 | |
| 4hy6 | FJ1 | Heat shock protein HSP 90-alpha | / | 0.459 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.459 | |
| 4olf | HFG | Proline--tRNA ligase | 6.1.1.15 | 0.459 | |
| 5aaj | HSC | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.459 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 1sqp | MYX | Cytochrome b | / | 0.458 | |
| 1u3r | 338 | Estrogen receptor beta | / | 0.458 | |
| 1ya3 | STR | Mineralocorticoid receptor | / | 0.458 | |
| 2azz | TCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.458 | |
| 2ovh | AS0 | Progesterone receptor | / | 0.458 | |
| 2w6o | OA3 | Biotin carboxylase | 6.3.4.14 | 0.458 | |
| 2wpw | ACO | Orf14 | / | 0.458 | |
| 3dg8 | RJ6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.458 | |
| 3dho | B2M | Streptogramin A acetyltransferase | 2.3.1 | 0.458 | |
| 4zqc | F6F | Tryptophan synthase alpha chain | / | 0.458 | |
| 1dkf | BMS | Retinoic acid receptor alpha | / | 0.457 | |
| 1nqu | RDL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.457 | |
| 1phe | PIY | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.457 | |
| 2g0g | SP0 | Peroxisome proliferator-activated receptor gamma | / | 0.457 | |
| 2k5t | COA | PanD regulatory factor | / | 0.457 | |
| 2y98 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.457 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.457 | |
| 3b9l | AZZ | Serum albumin | / | 0.457 | |
| 3bsy | ACO | UDP-N-acetylbacillosamine N-acetyltransferase | 2.3.1.203 | 0.457 | |
| 3e5a | VX6 | Aurora kinase A | 2.7.11.1 | 0.457 | |
| 3l71 | AZO | Cytochrome b | / | 0.457 | |
| 4dhy | S41 | Glucokinase | 2.7.1.2 | 0.457 | |
| 4mbs | MRV | C-C chemokine receptor type 5 | / | 0.457 | |
| 4p66 | MTX | Dihydrofolate reductase | / | 0.457 | |
| 4p6w | MOF | Glucocorticoid receptor | / | 0.457 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.457 | |
| 1fby | REA | Retinoic acid receptor RXR-alpha | / | 0.456 | |
| 1q20 | PLO | Sulfotransferase family cytosolic 2B member 1 | 2.8.2.2 | 0.456 | |
| 1s3y | TQT | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1tdu | DUR | Thymidylate synthase | / | 0.456 | |
| 1u2r | SO1 | Elongation factor 2 | / | 0.456 | |
| 2fzi | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 2pit | DHT | Androgen receptor | / | 0.456 | |
| 3elm | 24F | Collagenase 3 | 3.4.24 | 0.456 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.456 | |
| 3lfe | Z84 | Mitogen-activated protein kinase 14 | / | 0.456 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.456 | |
| 3znr | NU9 | Histone deacetylase 7 | 3.5.1.98 | 0.456 | |
| 3zvu | A8S | Abscisic acid receptor PYR1 | / | 0.456 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.456 | |
| 4a9o | A9O | Bromodomain-containing protein 2 | / | 0.456 | |
| 4hni | 16W | Casein kinase I isoform epsilon | 2.7.11.1 | 0.456 | |
| 1e1q | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.455 | |
| 1ia2 | TQ4 | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1sm2 | STU | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.455 | |
| 1uml | FR4 | Adenosine deaminase | 3.5.4.4 | 0.455 | |
| 2ao6 | R18 | Androgen receptor | / | 0.455 | |
| 2w3w | VG9 | Dihydrofolate reductase | / | 0.455 | |
| 2xvw | 9NR | Serum albumin | / | 0.455 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.455 | |
| 3ar5 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.455 | |
| 3dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 3el7 | PD3 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.455 | |
| 3ipq | 965 | Oxysterols receptor LXR-alpha | / | 0.455 | |
| 3jpu | TY4 | Transcriptional activator protein LasR | / | 0.455 | |
| 3kyt | HC2 | Nuclear receptor ROR-gamma | / | 0.455 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.455 | |
| 3p2h | NOO | Acyl-homoserine-lactone synthase | / | 0.455 | |
| 3qlw | N22 | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 3qlz | QLZ | Uncharacterized protein | / | 0.455 | |
| 4ddr | MMV | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 4f9m | FCM | Peroxisome proliferator-activated receptor gamma | / | 0.455 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.455 | |
| 4kln | AGS | Transitional endoplasmic reticulum ATPase | 3.6.4.6 | 0.455 | |
| 4s0v | SUV | Orexin receptor type 2 | / | 0.455 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.454 | |
| 1h35 | R01 | Squalene--hopene cyclase | 4.2.1.129 | 0.454 | |
| 1o5r | FR9 | Adenosine deaminase | 3.5.4.4 | 0.454 | |
| 1ohk | COP | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1pd8 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1q5d | EPB | Epothilone C/D epoxidase | 1.14 | 0.454 | |
| 1qxl | FR8 | Adenosine deaminase | 3.5.4.4 | 0.454 | |
| 1s9q | OHT | Estrogen-related receptor gamma | / | 0.454 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.454 | |
| 2h42 | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.454 | |
| 2mm3 | CHO | Gastrotropin | / | 0.454 | |
| 2psj | CEI | Renilla-luciferin 2-monooxygenase | 1.13.12.5 | 0.454 | |
| 2q7g | CCL | Pyrrolysine--tRNA ligase | / | 0.454 | |
| 2ze2 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.454 | |
| 3bfa | 9OD | Odorant binding protein ASP1 | / | 0.454 | |
| 3q0g | BCO | Probable enoyl-CoA hydratase echA8 | 4.2.1.17 | 0.454 | |
| 3qls | 55V | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 3t37 | FAD | Pyridoxine 4-oxidase | / | 0.454 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.454 | |
| 4a9m | P9M | Bromodomain-containing protein 2 | / | 0.454 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.454 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.454 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.454 | |
| 4jlk | 1NO | Deoxycytidine kinase | 2.7.1.74 | 0.454 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.454 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.454 | |
| 5bt4 | 2LO | Bromodomain-containing protein 4 | / | 0.454 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.454 | |
| 5jad | FB2 | Platelet-activating factor acetylhydrolase | 3.1.1.47 | 0.454 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.453 | |
| 1it7 | GUN | tRNA-guanine(15) transglycosylase | 2.4.2.48 | 0.453 | |
| 1p44 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.453 | |
| 1u1d | 181 | Uridine phosphorylase | 2.4.2.3 | 0.453 | |
| 1xiu | REA | Retinoic acid receptor RXR | / | 0.453 | |
| 1xuo | LA1 | Integrin alpha-L | / | 0.453 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.453 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.453 | |
| 2j0v | GDP | Rac-like GTP-binding protein ARAC7 | / | 0.453 | |
| 2q5o | TPW | Indole-3-pyruvate decarboxylase | 4.1.1.74 | 0.453 | |
| 2q5o | PPY | Indole-3-pyruvate decarboxylase | 4.1.1.74 | 0.453 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.453 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.453 | |
| 3d80 | Q22 | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 3ey4 | 352 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.453 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.453 | |
| 3k31 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.453 | |
| 3rgz | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.453 | |
| 4a4x | JUP | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.453 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 4gyz | D5M | Tyrosyl-DNA phosphodiesterase 2 | 3.1.4 | 0.453 | |
| 4h38 | 0YX | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.453 | |
| 4lvg | 20O | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.453 | |
| 4pv5 | CBW | Lactoylglutathione lyase | 4.4.1.5 | 0.453 | |
| 5kf2 | COA | Predicted acetyltransferase | / | 0.453 | |
| 5kgj | ACO | Predicted acetyltransferase | / | 0.453 | |
| 5g53 | NEC | Adenosine receptor A2a | / | 0.453 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1lhn | AON | Sex hormone-binding globulin | / | 0.452 | |
| 1mzn | BM6 | Retinoic acid receptor RXR-alpha | / | 0.452 | |
| 1nbm | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.452 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 1tl7 | FOK | Adenylate cyclase type 2 | / | 0.452 | |
| 1tl7 | FOK | Adenylate cyclase type 5 | / | 0.452 | |
| 1xls | REA | Retinoic acid receptor RXR-alpha | / | 0.452 | |
| 1yim | CM4 | Estrogen receptor | / | 0.452 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.452 | |
| 2ilt | NN1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.452 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.452 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 2x21 | PID | Peridinin-chlorophyll a-binding protein 1, chloroplastic | / | 0.452 | |
| 2zza | FOL | Dihydrofolate reductase | / | 0.452 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.452 | |
| 3c14 | FOK | Adenylate cyclase type 2 | / | 0.452 | |
| 3c14 | FOK | Adenylate cyclase type 5 | / | 0.452 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.452 | |
| 3k45 | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 3p2o | NAD | Bifunctional protein FolD | / | 0.452 | |
| 3qiz | QI2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.452 | |
| 3v49 | PK0 | Androgen receptor | / | 0.452 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.452 | |
| 3w1w | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.452 | |
| 4dp3 | MMV | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.452 | |
| 4ez8 | DHF | Thymidylate synthase | 2.1.1.45 | 0.452 | |
| 4g1n | NZT | Pyruvate kinase PKM | 2.7.1.40 | 0.452 | |
| 4hsh | QEI | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.452 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.451 | |
| 1icq | OPD | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.451 | |
| 1ly3 | COG | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1ohj | COP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1qzz | SAM | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.451 | |
| 1uwh | BAX | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.451 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.451 | |
| 2b37 | 8PS | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 2ij7 | TPF | Mycocyclosin synthase | 1.14.21.9 | 0.451 | |
| 2qd5 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.451 | |
| 2vr1 | ATF | Biotin carboxylase | 6.3.4.14 | 0.451 | |
| 3csd | EMO | Putative ketoacyl reductase | 1.3.1 | 0.451 | |
| 3cse | N22 | Uncharacterized protein | / | 0.451 | |
| 3cz0 | 9OD | Pheromone-binding protein ASP1 | / | 0.451 | |
| 3f0r | TSN | Histone deacetylase 8 | 3.5.1.98 | 0.451 | |
| 3hbb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.451 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.451 | |
| 3td8 | D2R | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.451 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.451 | |
| 4keb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.451 | |
| 4ea3 | 0NN | Nociceptin receptor | / | 0.451 | |
| 1fm6 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.450 | |
| 1k27 | MTM | S-methyl-5'-thioadenosine phosphorylase | / | 0.450 | |
| 1ove | 358 | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 1ppj | ANY | Cytochrome b | / | 0.450 | |
| 1t7f | DHT | Androgen receptor | / | 0.450 | |
| 1v7a | FRC | Adenosine deaminase | 3.5.4.4 | 0.450 | |
| 2agv | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.450 | |
| 2pun | ACP | Methylthioribose kinase | 2.7.1.100 | 0.450 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.450 | |
| 2vqj | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.450 | |
| 3ar7 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.450 | |
| 3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.450 | |
| 3inv | C50 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.450 | |
| 3std | MQ0 | Scytalone dehydratase | 4.2.1.94 | 0.450 | |
| 3t3q | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.450 | |
| 3ue4 | DB8 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.450 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.450 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 4at3 | LTI | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.450 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.450 | |
| 4d1o | H4B | Nitric oxide synthase, endothelial | 1.14.13.39 | 0.450 | |
| 4fdp | FAD | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.450 | |
| 4inb | 1F6 | Gag protein | / | 0.450 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.450 | |
| 4jv6 | 18F | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.450 | |
| 4jv8 | 1M1 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.450 | |
| 4l1x | NAP | Aldo-keto reductase family 1 member C2 | / | 0.450 | |
| 4lxd | 1XV | Apoptosis regulator Bcl-2 | / | 0.450 | |
| 4n1f | CZH | Obelin | / | 0.450 | |
| 4tjy | 3GN | Tankyrase-2 | 2.4.2.30 | 0.450 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.450 | |
| 4uyg | 73B | Bromodomain-containing protein 2 | / | 0.450 | |
| 5akk | 1P8 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.450 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1e1n | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.449 | |
| 1fkw | PUR | Adenosine deaminase | 3.5.4.4 | 0.449 | |
| 1fml | RTL | Retinol dehydratase | / | 0.449 | |
| 1g3m | PCQ | Estrogen sulfotransferase | 2.8.2.4 | 0.449 | |
| 1r00 | SAH | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.449 | |
| 1sqb | AZO | Cytochrome b | / | 0.449 | |
| 1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.449 | |
| 2fdy | D4G | Cytochrome P450 2A6 | 1.14.13 | 0.449 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 2uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.449 | |
| 2xtb | KRM | Adenosine kinase, putative | / | 0.449 | |
| 2yee | 2EC | Heat shock protein HSP 90-alpha | / | 0.449 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.449 | |
| 3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 3h18 | PMS | Esterase/lipase | / | 0.449 | |
| 3hk1 | B64 | Fatty acid-binding protein, adipocyte | / | 0.449 | |
| 3qlx | QLR | Uncharacterized protein | / | 0.449 | |
| 3tgu | WF3 | Cytochrome b | / | 0.449 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.449 | |
| 3ujl | A8S | Abscisic acid receptor PYL2 | / | 0.449 | |
| 3wiy | LC6 | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.449 | |
| 4a51 | DQ8 | Kinesin-like protein KIF11 | / | 0.449 | |
| 4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.449 | |
| 4bgi | I4I | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 4dch | 4DC | Glucokinase | 2.7.1.2 | 0.449 | |
| 4dph | P65 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.449 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.449 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.449 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.449 | |
| 4iyg | 1HU | Strictosidine synthase | 4.3.3.2 | 0.449 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.449 | |
| 5ab6 | CAA | Nonspecific lipid-transfer protein, putative | / | 0.449 | |
| 1al8 | DHP | Peroxisomal (S)-2-hydroxy-acid oxidase | 1.1.3.15 | 0.448 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.448 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.448 | |
| 1rx7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
| 1xu9 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.448 | |
| 2aa2 | AS4 | Mineralocorticoid receptor | / | 0.448 | |
| 2b36 | 5PP | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.448 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.448 | |
| 2obx | INI | 6,7-dimethyl-8-ribityllumazine synthase 2 | 2.5.1.78 | 0.448 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.448 | |
| 2x20 | PID | Peridinin-chlorophyll a-binding protein 1, chloroplastic | / | 0.448 | |
| 2xvq | 9DS | Serum albumin | / | 0.448 | |
| 2yjx | YJX | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 3ar6 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.448 | |
| 3c1o | NAP | Eugenol synthase | / | 0.448 | |
| 3exf | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.448 | |
| 3exf | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.448 | |
| 3gyf | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 3l8s | BFF | Mitogen-activated protein kinase 14 | / | 0.448 | |
| 3qlh | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.448 | |
| 3qlr | QLR | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 3s7a | 684 | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.448 | |
| 4bb6 | HD1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.448 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.448 | |
| 4hfr | 14M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.448 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.448 | |
| 4l49 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 1gt5 | BZQ | Odorant-binding protein | / | 0.447 | |
| 1jf0 | CZH | Obelin | / | 0.447 | |
| 1kce | CB3 | Thymidylate synthase | / | 0.447 | |
| 1kdk | DHT | Sex hormone-binding globulin | / | 0.447 | |
| 1kt3 | RTL | Retinol-binding protein 4 | / | 0.447 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.447 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.447 | |
| 1rjk | VDZ | Vitamin D3 receptor | / | 0.447 | |
| 1uhl | MEI | Retinoic acid receptor RXR-beta | / | 0.447 | |
| 1xg5 | NAP | Dehydrogenase/reductase SDR family member 11 | / | 0.447 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.447 | |
| 2bif | ANP | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 | 2.7.1.105 | 0.447 | |
| 2bkt | RPF | Renin | 3.4.23.15 | 0.447 | |
| 2e98 | B29 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.447 | |
| 2fsz | OHT | Estrogen receptor beta | / | 0.447 | |
| 2hl0 | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.447 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.447 | |
| 3czr | 3CZ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.447 | |
| 3dtt | NAP | NADP oxidoreductase, coenzyme F420-dependent | / | 0.447 | |
| 3eek | 53S | Uncharacterized protein | / | 0.447 | |
| 3iex | GMP | Purine nucleoside phosphorylase | / | 0.447 | |
| 3o73 | O73 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.447 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.447 | |
| 4a7b | 3W5 | Collagenase 3 | 3.4.24 | 0.447 | |
| 4eh8 | IRG | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 4eiy | ZMA | Adenosine receptor A2a | / | 0.447 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.447 | |
| 4i6h | 1C8 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.447 | |
| 4qa2 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.447 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.447 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 1d3p | BT3 | Prothrombin | 3.4.21.5 | 0.446 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1hfp | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1j3j | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.446 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.446 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 2ouz | C3D | Estrogen receptor | / | 0.446 | |
| 2pix | DHT | Androgen receptor | / | 0.446 | |
| 2pup | ADP | Methylthioribose kinase | 2.7.1.100 | 0.446 | |
| 2qqf | A1R | NAD-dependent protein deacetylase HST2 | 3.5.1 | 0.446 | |
| 2qw8 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.446 | |
| 3g4k | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.446 | |
| 3gbk | 2PQ | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 3gph | OID | Cytochrome P450 2E1 | 1.14.13 | 0.446 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 3oji | PYV | Abscisic acid receptor PYL3 | / | 0.446 | |
| 3qj5 | 022 | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.446 | |
| 3w0u | HPW | Lactoylglutathione lyase | 4.4.1.5 | 0.446 | |
| 3wav | DWV | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | 3.1.4.39 | 0.446 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 3zrb | OR8 | Progesterone receptor | / | 0.446 | |
| 4aos | NAP | Steroid monooxygenase | / | 0.446 | |
| 4dli | IRG | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 4iv4 | 1GS | Estrogen receptor | / | 0.446 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.446 | |
| 4ky4 | 04J | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.446 | |
| 4li6 | 1XO | Tankyrase-1 | 2.4.2.30 | 0.446 | |
| 4o4f | ATP | Kinase | / | 0.446 | |
| 4u8i | FDA | UDP-galactopyranose mutase | / | 0.446 | |
| 4u9v | ACO | N-alpha-acetyltransferase 40 | 2.3.1 | 0.446 | |
| 5bn3 | ADP | V-type ATP synthase alpha chain | / | 0.446 | |
| 5bn3 | ADP | NEQ263 | / | 0.446 | |
| 5kf2 | ACO | Predicted acetyltransferase | / | 0.446 | |
| 1bmf | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.445 | |
| 1bmf | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.445 | |
| 1dna | CB3 | Thymidylate synthase | / | 0.445 | |
| 1kmv | LII | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.445 | |
| 1s7g | NAD | NAD-dependent protein deacylase 2 | / | 0.445 | |
| 1sqq | OST | Cytochrome b | / | 0.445 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.445 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.445 | |
| 1u0h | FOK | Adenylate cyclase type 2 | / | 0.445 | |
| 1u0h | FOK | Adenylate cyclase type 5 | / | 0.445 | |
| 2jbs | FMN | p-hydroxyphenylacetate 3-hydroxylase, oxygenase component | / | 0.445 | |
| 2zb8 | IMN | Prostaglandin reductase 2 | 1.3.1.48 | 0.445 | |
| 3ant | S82 | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.445 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.445 | |
| 3hwx | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.445 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.445 | |
| 3njo | P2M | Abscisic acid receptor PYR1 | / | 0.445 | |
| 3ntz | 3TZ | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3sgy | 06W | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3sh2 | 5DR | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.445 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.445 | |
| 4g21 | 0VP | Vitamin D3 receptor A | / | 0.445 | |
| 4ktk | KTK | Cytochrome P450 | / | 0.445 | |
| 4pzr | COA | Histone acetyltransferase p300 | / | 0.445 | |
| 5d7p | OCZ | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.445 | |
| 5ej9 | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.445 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1m7a | MQU | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1n4h | REA | Nuclear receptor ROR-beta | / | 0.444 | |
| 1n8w | COA | Malate synthase G | / | 0.444 | |
| 1t4v | 14A | Prothrombin | 3.4.21.5 | 0.444 | |
| 1t65 | DHT | Androgen receptor | / | 0.444 | |
| 1y6q | TDI | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | 3.2.2.9 | 0.444 | |
| 1yrc | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 2acw | UPG | Glycosyltransferase | / | 0.444 | |
| 2bx8 | AZQ | Serum albumin | / | 0.444 | |
| 2cbq | TH2 | Neocarzinostatin | / | 0.444 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 2dwp | ACP | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 | 2.7.1.105 | 0.444 | |
| 2gpv | OHT | Estrogen-related receptor gamma | / | 0.444 | |
| 2oth | NIM | Basic phospholipase A2 VRV-PL-VIIIa | 3.1.1.4 | 0.444 | |
| 2pg0 | FAD | Acyl-CoA dehydrogenase | / | 0.444 | |
| 2yek | EAM | Bromodomain-containing protein 2 | / | 0.444 | |
| 3biy | 01K | Histone acetyltransferase p300 | / | 0.444 | |
| 3c3d | FO1 | 2-phospho-L-lactate transferase | / | 0.444 | |
| 3d77 | NBB | Pheromone-binding protein ASP1 | / | 0.444 | |
| 3eei | MTM | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | / | 0.444 | |
| 3ghv | GHC | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.444 | |
| 3nxr | D2D | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 3p6p | A6B | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 3pft | FMN | Flavin reductase | / | 0.444 | |
| 3qdz | PRO_ALA_PRO_ARG | Prothrombin | 3.4.21.5 | 0.444 | |
| 3t8x | T8X | T-cell surface glycoprotein CD1b | / | 0.444 | |
| 3vrt | YS2 | Vitamin D3 receptor | / | 0.444 | |
| 3zec | ANP | Adenosine monophosphate-protein transferase SoFic | 2.7.7.n1 | 0.444 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 4h98 | 14Q | Uncharacterized protein | / | 0.444 | |
| 4i9i | 1DY | Tankyrase-1 | 2.4.2.30 | 0.444 | |
| 4jq4 | IMN | Aldo-keto reductase family 1 member C2 | / | 0.444 | |
| 4lb2 | DM5 | Serum albumin | / | 0.444 | |
| 4lsa | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.444 | |
| 4muw | 2F4 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 4rgs | V55 | Repressor protein | / | 0.444 | |
| 4x5g | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 5gcn | COA | HAT A1 | / | 0.444 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.444 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.443 | |
| 1gwc | GTX | Glutathione S-transferase 1 | / | 0.443 | |
| 1q9m | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 1rd4 | L08 | Integrin alpha-L | / | 0.443 | |
| 1uof | PNN | Deacetoxycephalosporin C synthase | 1.14.20.1 | 0.443 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 2ab8 | MTP | Adenosine kinase | 2.7.1.20 | 0.443 | |
| 2c9e | PID | Peridinin-chlorophyll a protein, high-salt form | / | 0.443 | |
| 2g2h | P16 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.443 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.443 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.443 | |
| 2p7z | OHT | Estrogen-related receptor gamma | / | 0.443 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2w3v | TOP | Dihydrofolate reductase | / | 0.443 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.443 | |
| 2ydw | WSH | Bromodomain-containing protein 2 | / | 0.443 | |
| 3ar4 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.443 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.443 | |
| 3d2d | REN | Reticuline oxidase | 1.21.3.3 | 0.443 | |
| 3d78 | NBB | Pheromone-binding protein ASP1 | / | 0.443 | |
| 3eks | CY9 | Actin-5C | / | 0.443 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.443 | |
| 3m2v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.443 | |
| 3rg9 | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 3uvv | REA | Retinoic acid receptor RXR-alpha | / | 0.443 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.443 | |
| 3zra | ORB | Progesterone receptor | / | 0.443 | |
| 4ajm | 3A6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
| 4fhf | 0TT | Spore photoproduct lyase | / | 0.443 | |
| 4g47 | TZF | Mycocyclosin synthase | 1.14.21.9 | 0.443 | |
| 4hkf | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.443 | |
| 4n1g | CEI | Obelin | / | 0.443 | |
| 4nc3 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.443 | |
| 4ruj | VDX | Vitamin D3 receptor A | / | 0.443 | |
| 4ug2 | NGI | Adenosine receptor A2a | / | 0.443 | |
| 1axw | MTX | Thymidylate synthase | / | 0.442 | |
| 1db5 | 6IN | Phospholipase A2, membrane associated | / | 0.442 | |
| 1dtp | APU | Diphtheria toxin | / | 0.442 | |
| 1e90 | MYC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 1f5f | DHT | Sex hormone-binding globulin | / | 0.442 | |
| 1fcx | 184 | Retinoic acid receptor gamma | / | 0.442 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1iyz | NDP | Probable quinone oxidoreductase | / | 0.442 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.442 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.442 | |
| 2acl | REA | Retinoic acid receptor RXR-alpha | / | 0.442 | |
| 2gvc | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.442 | |
| 2reh | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.442 | |
| 2yki | YKI | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 3ggs | 2FD | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
| 3i1y | 33N | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.442 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 3kdi | A8S | Abscisic acid receptor PYL2 | / | 0.442 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.442 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.442 | |
| 3o56 | ZG1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.442 | |
| 3oap | REA | Retinoic acid receptor RXR-alpha | / | 0.442 | |
| 3ql3 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 3zbn | COA | 3-ketoacyl-CoA thiolase-like protein | / | 0.442 | |
| 4agw | NG7 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.442 | |
| 4ajf | F03 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
| 4azw | ATP | O-antigen chain terminator bifunctional methyltransferase/kinase WbdD | / | 0.442 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.442 | |
| 4nx7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4paa | THG | Dimethylglycine dehydrogenase, mitochondrial | 1.5.8.4 | 0.442 | |
| 4x5f | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1iid | NHM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.441 | |
| 1m8e | H4B | Nitric oxide synthase, inducible | 1.14.13.39 | 0.441 | |
| 1mvc | BM6 | Retinoic acid receptor RXR-alpha | / | 0.441 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 1piw | NAP | NADP-dependent alcohol dehydrogenase 6 | 1.1.1.2 | 0.441 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.441 | |
| 1sqn | NDR | Progesterone receptor | / | 0.441 | |
| 2aa5 | STR | Mineralocorticoid receptor | / | 0.441 | |
| 2e99 | B08 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.441 | |
| 2hm9 | TRR | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 2k62 | ITL | Fatty acid-binding protein, liver | / | 0.441 | |
| 2m56 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 2ovv | PFH | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 2vd0 | D27 | Hematopoietic prostaglandin D synthase | / | 0.441 | |
| 2x9v | TMQ | Pteridine reductase | / | 0.441 | |
| 2xkc | 4VQ | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.441 | |
| 3dds | 26B | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.441 | |
| 3djf | BC3 | Purine nucleoside phosphorylase | / | 0.441 | |
| 3ghw | GHW | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.441 | |
| 3nmn | PYV | Abscisic acid receptor PYL1 | / | 0.441 | |
| 3o9l | LPN | Renin | 3.4.23.15 | 0.441 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 3up0 | D7S | aceDAF-12 | / | 0.441 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.441 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.441 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.441 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.441 | |
| 4g8j | THM | Uridine phosphorylase | / | 0.441 | |
| 4hut | ATP | Cob(I)yrinic acid a,c-diamide adenosyltransferase | 2.5.1.17 | 0.441 | |
| 4hw3 | 19G | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.441 | |
| 4i2p | G73 | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 4jva | 1OR | cAMP-dependent protein kinase type II-beta regulatory subunit | / | 0.441 | |
| 4oal | 245 | Cytokinin dehydrogenase 4 | / | 0.441 | |
| 4py6 | R78 | Bromodomain protein, putative | / | 0.441 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.440 | |
| 1dgf | NDP | Catalase | 1.11.1.6 | 0.440 | |
| 1fx9 | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.440 | |
| 1jut | LYD | Thymidylate synthase | / | 0.440 | |
| 1kb9 | SMA | Cytochrome b | / | 0.440 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.440 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1r9o | FLP | Cytochrome P450 2C9 | / | 0.440 | |
| 1re9 | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 1rx6 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.440 | |
| 1uio | HPR | Adenosine deaminase | 3.5.4.4 | 0.440 | |
| 1xng | DND | NH(3)-dependent NAD(+) synthetase | 6.3.1.5 | 0.440 | |
| 1xq3 | R18 | Androgen receptor | / | 0.440 | |
| 1z0z | NAD | NAD kinase | / | 0.440 | |
| 2ati | IHU | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.440 | |
| 2bbq | PFG | Thymidylate synthase | / | 0.440 | |
| 2bn4 | FAD | NADPH--cytochrome P450 reductase | / | 0.440 | |
| 2c3p | 1TP | Pyruvate synthase | / | 0.440 | |
| 2cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 2gpu | OHT | Estrogen-related receptor gamma | / | 0.440 | |
| 2hko | FAD | Lysine-specific histone demethylase 1A | 1 | 0.440 | |
| 2ob0 | ACO | N-alpha-acetyltransferase 50 | / | 0.440 | |
| 2p8u | COA | Hydroxymethylglutaryl-CoA synthase, cytoplasmic | 2.3.3.10 | 0.440 | |
| 2pir | DHT | Androgen receptor | / | 0.440 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.440 | |
| 2w71 | L23 | Biotin carboxylase | 6.3.4.14 | 0.440 | |
| 2wnb | C5P | CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 | 2.4.99.4 | 0.440 | |
| 2zce | PYL | Pyrrolysine--tRNA ligase | / | 0.440 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3fnu | 006 | HAP protein | / | 0.440 | |
| 3fu9 | KIB | Laccase-1 | 1.10.3.2 | 0.440 | |
| 3hbf | MYC | Flavonoid 3-O-glucosyltransferase | 2.4.1 | 0.440 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3nwl | NDP | Catalase | 1.11.1.6 | 0.440 | |
| 3p6n | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 3pm9 | FAD | Putative oxidoreductase | / | 0.440 | |
| 3vru | YS3 | Vitamin D3 receptor | / | 0.440 | |
| 4a9h | TVP | Bromodomain-containing protein 2 | / | 0.440 | |
| 4eh9 | 0OQ | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 4gi4 | 0EX | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.440 | |
| 4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 4iw6 | 1GU | Estrogen receptor | / | 0.440 | |
| 4jvl | EST | Estrogen sulfotransferase | 2.8.2.4 | 0.440 | |
| 4k4j | 1O8 | Retinoic acid receptor RXR-alpha | / | 0.440 | |
| 4uda | DEX | Mineralocorticoid receptor | / | 0.440 | |
| 5d1b | TSN | Histone deacetylase 8 | 3.5.1.98 | 0.440 | |
| 5epe | SAH | Uncharacterized protein | / | 0.440 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.440 |