sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2q46 | NAP | Uncharacterized protein At5g02240 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2q46 | NAP | Uncharacterized protein At5g02240 | / | 1.000 | |
| 1ybm | NAP | Uncharacterized protein At5g02240 | / | 0.598 | |
| 2q4b | NAP | Uncharacterized protein At5g02240 | / | 0.586 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.515 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.506 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.504 | |
| 4fnc | HMU | G/T mismatch-specific thymine DNA glycosylase | 3.2.2.29 | 0.502 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.498 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.493 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.492 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.490 | |
| 3sdk | P3N | Proteasome subunit beta type-5 | 3.4.25.1 | 0.489 | |
| 3sdk | P3N | Proteasome subunit beta type-6 | 3.4.25.1 | 0.489 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.489 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.487 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.485 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.484 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.484 | |
| 2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.484 | |
| 3oev | 3OE | Proteasome subunit beta type-5 | 3.4.25.1 | 0.484 | |
| 3oev | 3OE | Proteasome subunit beta type-6 | 3.4.25.1 | 0.484 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.483 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.482 | |
| 3wrj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.481 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.481 | |
| 4jic | FMN | GTN Reductase | / | 0.481 | |
| 5ein | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.480 | |
| 1pjk | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.479 | |
| 2x0r | NAD | Malate dehydrogenase | / | 0.479 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.479 | |
| 4gyz | D5M | Tyrosyl-DNA phosphodiesterase 2 | 3.1.4 | 0.479 | |
| 4k5s | PM0 | Oxygenase | / | 0.479 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.478 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.478 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.478 | |
| 4l4x | NDP | AmphI | / | 0.478 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.477 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.477 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.477 | |
| 3gon | ANP | Phosphomevalonate kinase | / | 0.477 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.477 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.477 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.477 | |
| 1bxo | PP7 | Penicillopepsin-1 | 3.4.23.20 | 0.476 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.476 | |
| 5cyo | GDP | Septin-9 | / | 0.476 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.475 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.474 | |
| 1yrc | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.474 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.474 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.474 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.473 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.472 | |
| 1juv | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.471 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.471 | |
| 3h86 | AP5 | Adenylate kinase | / | 0.471 | |
| 4jin | 1L7 | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.471 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.471 | |
| 1jn0 | NDP | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.470 | |
| 1kvs | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.470 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.470 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.470 | |
| 2y1t | DUD | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.470 | |
| 3u9e | COA | Lmo1369 protein | / | 0.470 | |
| 4k28 | NAD | Shikimate dehydrogenase family protein | / | 0.470 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.470 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.469 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.469 | |
| 3e8x | NAP | BH1520 protein | / | 0.469 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.469 | |
| 3ljt | LA3 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.469 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.469 | |
| 5e8j | SAH | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.469 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.468 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.468 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.468 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.468 | |
| 1hyg | NAP | L-2-hydroxycarboxylate dehydrogenase (NAD(P)(+)) | / | 0.467 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.467 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.467 | |
| 2zsb | ADP | Pantothenate kinase | 2.7.1.33 | 0.467 | |
| 3cls | FAD | Electron transfer flavoprotein subunit alpha | / | 0.467 | |
| 3mvq | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.467 | |
| 4nmd | FDA | Bifunctional protein PutA | / | 0.467 | |
| 1jqi | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | / | 0.466 | |
| 1osv | CHC | Bile acid receptor | / | 0.466 | |
| 1szj | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.466 | |
| 2bxm | IMN | Serum albumin | / | 0.466 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.466 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.466 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.466 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.466 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.466 | |
| 1esv | LAR | Actin, alpha skeletal muscle | / | 0.465 | |
| 1gpd | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.465 | |
| 1men | GAR | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.465 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.465 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.465 | |
| 2npa | MMB | Peroxisome proliferator-activated receptor alpha | / | 0.465 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.465 | |
| 1hdg | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.464 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 1pjc | NAD | Alanine dehydrogenase | / | 0.464 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 1qmf | KEF | Penicillin-binding protein 2x | / | 0.464 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.464 | |
| 2gmj | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.464 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.464 | |
| 3kga | LX9 | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.464 | |
| 3wfj | NAD | 2-dehydropantoate 2-reductase | / | 0.464 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.464 | |
| 4ew2 | DXY | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.464 | |
| 4h4v | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.464 | |
| 4qxq | 1YE | Stimulator of interferon genes protein | / | 0.464 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.463 | |
| 1npv | L27 | Gag-Pol polyprotein | 3.4.23.16 | 0.463 | |
| 2b4t | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.463 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.463 | |
| 4lht | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.463 | |
| 5bsg | NAP | Pyrroline-5-carboxylate reductase | / | 0.463 | |
| 1c2t | NHS | Phosphoribosylglycinamide formyltransferase | / | 0.462 | |
| 2ahr | NAP | Pyrroline-5-carboxylate reductase | / | 0.462 | |
| 2bri | ANP | Uridylate kinase | 2.7.4.22 | 0.462 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 3ndc | SAH | Precorrin-4 C(11)-methyltransferase | 2.1.1.133 | 0.462 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.462 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.462 | |
| 4xgx | ADP | FAD:protein FMN transferase | / | 0.462 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.462 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.462 | |
| 1aj8 | COA | Citrate synthase | / | 0.461 | |
| 1cjk | FOK | Adenylate cyclase type 2 | / | 0.461 | |
| 1cjk | FOK | Adenylate cyclase type 5 | / | 0.461 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.461 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.461 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1f0y | CAA | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.461 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.461 | |
| 1p9w | ANP | Type II secretion system protein E | / | 0.461 | |
| 1xel | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.461 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.461 | |
| 2hma | SAM | tRNA-specific 2-thiouridylase MnmA | / | 0.461 | |
| 3d7k | D7K | Benzaldehyde lyase | / | 0.461 | |
| 3p0h | FSE | Putative tyrosyl-tRNA synthetase | / | 0.461 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.461 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.461 | |
| 4z0g | 5GP | Inosine-5'-monophosphate dehydrogenase | / | 0.461 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 1kc1 | NDP | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.460 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.460 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.460 | |
| 1xq6 | NAP | Uncharacterized protein At5g02240 | / | 0.460 | |
| 2hs8 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.460 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.460 | |
| 3umv | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.460 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.460 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.460 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.460 | |
| 1ihy | APR | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.459 | |
| 1kvk | ATP | Mevalonate kinase | 2.7.1.36 | 0.459 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 1vc2 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.459 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.459 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.459 | |
| 4guk | P2G | Neuronal calcium sensor 1 | / | 0.459 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.458 | |
| 2ath | 3EA | Peroxisome proliferator-activated receptor gamma | / | 0.458 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.458 | |
| 2rkv | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.458 | |
| 2yxu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.458 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.458 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.458 | |
| 4ji9 | 1M3 | Tyrosine-protein kinase JAK2 | / | 0.458 | |
| 4l4f | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.458 | |
| 4wuc | ANP | DNA gyrase subunit B | / | 0.458 | |
| 1bzf | TMQ | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 1cs4 | FOK | Adenylate cyclase type 2 | / | 0.457 | |
| 1cs4 | FOK | Adenylate cyclase type 5 | / | 0.457 | |
| 1dbv | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.457 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 1hdo | NAP | Flavin reductase (NADPH) | / | 0.457 | |
| 1in5 | ADP | Holliday junction ATP-dependent DNA helicase RuvB | / | 0.457 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.457 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.457 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.457 | |
| 2ijg | FAD | Cryptochrome DASH, chloroplastic/mitochondrial | / | 0.457 | |
| 3cyz | 9OD | Pheromone-binding protein ASP1 | / | 0.457 | |
| 3dog | NNN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.457 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.457 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.457 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.457 | |
| 4cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.457 | |
| 4o63 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.457 | |
| 4yco | FMN | tRNA-dihydrouridine(16) synthase | / | 0.457 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.457 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.456 | |
| 1mei | XMP | Inosine-5'-monophosphate dehydrogenase | / | 0.456 | |
| 1ng4 | FAD | Glycine oxidase | 1.4.3.19 | 0.456 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.456 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.456 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.456 | |
| 3n7u | NAD | Formate dehydrogenase, chloroplastic/mitochondrial | / | 0.456 | |
| 3r83 | Z14 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 4dbv | NDP | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.456 | |
| 4ew3 | DXZ | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.456 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.456 | |
| 4kip | 1R9 | Mitogen-activated protein kinase 14 | / | 0.456 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.456 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 2d8a | NAD | L-threonine 3-dehydrogenase | / | 0.455 | |
| 2gqw | FAD | Ferredoxin reductase | / | 0.455 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.455 | |
| 2z4y | 252 | Geranylgeranyl pyrophosphate synthase | / | 0.455 | |
| 3dt1 | P40 | Mitogen-activated protein kinase 14 | / | 0.455 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.455 | |
| 3inm | NDP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.455 | |
| 3kji | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.455 | |
| 3maa | FKP | Adenylate cyclase type 2 | / | 0.455 | |
| 3maa | FKP | Adenylate cyclase type 5 | / | 0.455 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.455 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.455 | |
| 3ssm | SAH | Mycinamicin VI 2''-O-methyltransferase | / | 0.455 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.455 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.455 | |
| 4f6w | 0SS | Cyclin-dependent kinase 8 | 2.7.11.22 | 0.455 | |
| 4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.455 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.455 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.455 | |
| 4gte | MEF | Flavin-dependent thymidylate synthase | 2.1.1.148 | 0.455 | |
| 4kzo | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.455 | |
| 4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.455 | |
| 1fwk | ADP | Homoserine kinase | 2.7.1.39 | 0.454 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.454 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.454 | |
| 2brb | PFQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.454 | |
| 2f3r | G5P | Guanylate kinase | 2.7.4.8 | 0.454 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 2xyu | Q9G | Ephrin type-A receptor 4 | 2.7.10.1 | 0.454 | |
| 3b2s | B2S | Trichothecene 3-O-acetyltransferase | / | 0.454 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.454 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.454 | |
| 4l6g | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.454 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.454 | |
| 4zoh | FAD | Putative oxidoreductase FAD-binding subunit | / | 0.454 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1esq | TZP | Hydroxyethylthiazole kinase | / | 0.453 | |
| 1g4t | FTP | Thiamine-phosphate synthase | / | 0.453 | |
| 1i7g | AZ2 | Peroxisome proliferator-activated receptor alpha | / | 0.453 | |
| 1k6v | XN2 | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 1mei | MOA | Inosine-5'-monophosphate dehydrogenase | / | 0.453 | |
| 1pmn | 984 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.453 | |
| 1qy5 | NEC | Endoplasmin | / | 0.453 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.453 | |
| 2g2z | COZ | Malonyl CoA-acyl carrier protein transacylase | 2.3.1.39 | 0.453 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.453 | |
| 2xtn | GTP | GTPase IMAP family member 2 | / | 0.453 | |
| 3ele | PLP | Aminotransferase | / | 0.453 | |
| 3gob | HXX | DdmC | / | 0.453 | |
| 3ijd | C2F | Methylenetetrahydrofolate reductase | / | 0.453 | |
| 3mje | NDP | AmphB | / | 0.453 | |
| 3tr0 | 5GP | Guanylate kinase | / | 0.453 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.453 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 4juf | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.453 | |
| 1c2t | GAR | Phosphoribosylglycinamide formyltransferase | / | 0.452 | |
| 1e5q | NDP | Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] | 1.5.1.10 | 0.452 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.452 | |
| 1jkx | 138 | Phosphoribosylglycinamide formyltransferase | / | 0.452 | |
| 1rdw | LAR | Actin, alpha skeletal muscle | / | 0.452 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.452 | |
| 1vik | BAY | Gag-Pol polyprotein | / | 0.452 | |
| 2bgl | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.452 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.452 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 2lfo | GCH | Fatty acid-binding protein, liver | / | 0.452 | |
| 2pb4 | SAH | Diphthine synthase | / | 0.452 | |
| 2q0l | FAD | Thioredoxin reductase | 1.8.1.9 | 0.452 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.452 | |
| 2zui | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 3gnq | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.452 | |
| 3i59 | N6R | CRP-like cAMP-activated global transcriptional regulator | / | 0.452 | |
| 3ieu | GDP | GTPase Era | / | 0.452 | |
| 3kb1 | ADP | Iron-sulfur cluster carrier protein | / | 0.452 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 3sc1 | 3S1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.452 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.452 | |
| 4iae | 1DX | Alr2278 protein | / | 0.452 | |
| 4m49 | 22Y | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.452 | |
| 4yek | THM | Thymidine phosphorylase | / | 0.452 | |
| 1g67 | TZP | Thiamine-phosphate synthase | / | 0.451 | |
| 1m75 | CAA | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.451 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.451 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 2j5x | GSP | ADP-ribosylation factor 6 | / | 0.451 | |
| 2pau | D5M | 5'-deoxynucleotidase YfbR | / | 0.451 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.451 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.451 | |
| 3td7 | FAD | Probable FAD-linked sulfhydryl oxidase R596 | 1.8.3.2 | 0.451 | |
| 3tnl | NAD | Shikimate dehydrogenase (NADP(+)) | / | 0.451 | |
| 4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.451 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 4bva | T3 | Ketimine reductase mu-crystallin | 1.5.1.25 | 0.451 | |
| 4h4q | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.451 | |
| 4ips | 1G4 | Mycocyclosin synthase | 1.14.21.9 | 0.451 | |
| 4ku2 | MYA | 3-oxoacyl-[ACP] synthase III | / | 0.451 | |
| 4l49 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 4l7f | 1V5 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.451 | |
| 4xg1 | LLP | Diaminopimelate decarboxylase | / | 0.451 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.450 | |
| 2dv3 | SAH | Diphthine synthase | / | 0.450 | |
| 2dwb | ANP | Aurora kinase A | 2.7.11.1 | 0.450 | |
| 2ev9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.450 | |
| 2ix5 | FAD | Acyl-coenzyme A oxidase 4, peroxisomal | 1.3.3.6 | 0.450 | |
| 2qfx | NDP | Isocitrate dehydrogenase [NADP], mitochondrial | 1.1.1.42 | 0.450 | |
| 3cjf | SAV | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.450 | |
| 3lj3 | WYE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.450 | |
| 3vcy | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.450 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.450 | |
| 3zon | IK1 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.450 | |
| 4h1m | 0YJ | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.450 | |
| 4l3j | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.450 | |
| 4mkh | AP5 | Adenylate kinase | / | 0.450 | |
| 4tyq | AP5 | Adenylate kinase | / | 0.450 | |
| 5a3c | NAD | SIR2 family protein | / | 0.450 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.450 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.449 | |
| 1geb | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.449 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 1ppm | 0P1 | Penicillopepsin-1 | 3.4.23.20 | 0.449 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 1zio | AP5 | Adenylate kinase | / | 0.449 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.449 | |
| 2ep7 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.449 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.449 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.449 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.449 | |
| 2qw0 | 34Z | 4-chlorobenzoyl CoA ligase | / | 0.449 | |
| 2xfs | J01 | Uncharacterized protein | / | 0.449 | |
| 3ceh | AVE | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.449 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.449 | |
| 3hrf | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.449 | |
| 3phj | DHK | Shikimate dehydrogenase (NADP(+)) | / | 0.449 | |
| 4a61 | ANP | Plasmid segregation protein ParM | / | 0.449 | |
| 4boy | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.449 | |
| 4c9o | CAM | Cytochrome P450 | / | 0.449 | |
| 4emt | C2E | Stimulator of interferon genes protein | / | 0.449 | |
| 4fv1 | EK4 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.449 | |
| 4gkm | 683 | Anthranilate phosphoribosyltransferase | / | 0.449 | |
| 4rww | 2BA | Lmo2692 protein | / | 0.449 | |
| 1c9k | 5GP | Bifunctional adenosylcobalamin biosynthesis protein CobU | / | 0.448 | |
| 1dg8 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1u3c | FAD | Cryptochrome-1 | / | 0.448 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.448 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 2owk | SAH | Diphthine synthase | / | 0.448 | |
| 2rl2 | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.448 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.448 | |
| 3a14 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.448 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 3flz | FLZ | Mitogen-activated protein kinase 14 | / | 0.448 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.448 | |
| 3hbb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.448 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.448 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 4dzz | ADP | Plasmid partitioning protein ParF | / | 0.448 | |
| 4lxh | C1E | Alpha/beta hydrolase fold | / | 0.448 | |
| 5a3b | APR | SIR2 family protein | / | 0.448 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.447 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.447 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.447 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.447 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 1zc3 | GNP | Ras-related protein Ral-A | / | 0.447 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 2pch | SAH | Diphthine synthase | / | 0.447 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 2wec | PP5 | Penicillopepsin-1 | 3.4.23.20 | 0.447 | |
| 2y3s | TIR | TamL | / | 0.447 | |
| 3dds | 26B | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.447 | |
| 3gol | XND | Genome polyprotein | 2.7.7.48 | 0.447 | |
| 3i6r | J5Z | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.447 | |
| 3ii4 | 3II | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.447 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.447 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.447 | |
| 3lxi | CAM | Cytochrome P450 | / | 0.447 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 3s87 | ADP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.447 | |
| 3t3q | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.447 | |
| 3v1y | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1, cytosolic | 1.2.1.12 | 0.447 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.447 | |
| 4h4z | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.447 | |
| 4y9q | C2E | Uncharacterized protein | / | 0.447 | |
| 5fko | TDC | Tetracycline repressor protein class D | / | 0.447 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.446 | |
| 1ju9 | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.446 | |
| 1nhh | ANP | DNA mismatch repair protein MutL | / | 0.446 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.446 | |
| 2ab8 | ACP | Adenosine kinase | 2.7.1.20 | 0.446 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.446 | |
| 2hsd | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.446 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.446 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.446 | |
| 3f63 | GTX | Glutathione transferase GST1-4 | / | 0.446 | |
| 3k6l | 2BB | Peptide deformylase | 3.5.1.88 | 0.446 | |
| 3l0d | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.446 | |
| 3s3v | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3sz0 | FAD | Sulfide-quinone reductase | / | 0.446 | |
| 3vx4 | ATP | Putative ABC transporter, ATP-binding protein ComA | / | 0.446 | |
| 4die | C5P | Cytidylate kinase | / | 0.446 | |
| 4ejg | NCT | Cytochrome P450 2A13 | 1.14.14.1 | 0.446 | |
| 4ejh | 0QA | Cytochrome P450 2A13 | 1.14.14.1 | 0.446 | |
| 4g3r | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 4l4c | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 4wa9 | AXI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.446 | |
| 5a88 | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.446 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.446 | |
| 5hws | NAP | 2-dehydropantoate 2-reductase | / | 0.446 | |
| 4z35 | ON9 | Lysophosphatidic acid receptor 1 | / | 0.446 | |
| 1a4i | NDP | C-1-tetrahydrofolate synthase, cytoplasmic | 1.5.1.5 | 0.445 | |
| 1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.445 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.445 | |
| 1c3e | NHR | Phosphoribosylglycinamide formyltransferase | / | 0.445 | |
| 1ep1 | FMN | Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit | 1.3.1.14 | 0.445 | |
| 1ihx | SND | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.445 | |
| 1jol | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 1rm5 | NDP | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.445 | |
| 2brm | DFZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 2eud | GCQ | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.445 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 3c14 | FOK | Adenylate cyclase type 2 | / | 0.445 | |
| 3c14 | FOK | Adenylate cyclase type 5 | / | 0.445 | |
| 3clb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.445 | |
| 3dj4 | UD1 | Bifunctional protein GlmU | / | 0.445 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.445 | |
| 3pm0 | BHF | Cytochrome P450 1B1 | / | 0.445 | |
| 3u8k | 09P | Acetylcholine-binding protein | / | 0.445 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.445 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.445 | |
| 4dpl | NAP | Malonyl-CoA reductase | 1.2.1.75 | 0.445 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.445 | |
| 4fmx | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.445 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.445 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.445 | |
| 4ien | COA | Putative acyl-CoA hydrolase | / | 0.445 | |
| 4lk3 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.445 | |
| 4rnu | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.445 | |
| 4rpg | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.445 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.445 | |
| 4zj8 | SUV | Orexin receptor type 1 | / | 0.445 | |
| 1j0x | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.444 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1owl | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.444 | |
| 1phh | FAD | p-hydroxybenzoate hydroxylase | / | 0.444 | |
| 1qo8 | FAD | Fumarate reductase flavoprotein subunit | / | 0.444 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.444 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 2iyp | NAP | 6-phosphogluconate dehydrogenase, decarboxylating | 1.1.1.44 | 0.444 | |
| 2p33 | J07 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.444 | |
| 2vz6 | FEF | Calcium/calmodulin-dependent protein kinase type II subunit alpha | 2.7.11.17 | 0.444 | |
| 2zev | B71 | Geranylgeranyl pyrophosphate synthase | / | 0.444 | |
| 3dtt | NAP | NADP oxidoreductase, coenzyme F420-dependent | / | 0.444 | |
| 3lfm | 3DT | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.444 | |
| 3nuu | JOZ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.444 | |
| 3nwq | 2NC | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 3qw4 | U5P | Orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative | / | 0.444 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.444 | |
| 4chq | CWU | Integrase | / | 0.444 | |
| 4kne | 1CY | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 4kpr | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.444 | |
| 4ktk | KTK | Cytochrome P450 | / | 0.444 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.444 | |
| 4qys | PLR | Tryptophan synthase beta chain 2 | 4.2.1.20 | 0.444 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.444 | |
| 4z5w | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.444 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.443 | |
| 1jed | ADP | Sulfate adenylyltransferase | / | 0.443 | |
| 1nfr | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.443 | |
| 1wng | SAH | Diphthine synthase | / | 0.443 | |
| 2b7a | IZA | Tyrosine-protein kinase JAK2 | / | 0.443 | |
| 2e16 | SAH | Diphthine synthase | / | 0.443 | |
| 2r26 | CMC | Citrate synthase | 2.3.3.16 | 0.443 | |
| 2ym2 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.443 | |
| 3ijo | B4D | Glutamate receptor 2 | / | 0.443 | |
| 3qc9 | ADP | Rhodopsin kinase | / | 0.443 | |
| 3sp6 | IL2 | Peroxisome proliferator-activated receptor alpha | / | 0.443 | |
| 3tjs | D0R | Cytochrome P450 3A4 | / | 0.443 | |
| 3tqh | NDP | Quinone oxidoreductase | / | 0.443 | |
| 3tvu | B37 | Acetyl-CoA carboxylase | / | 0.443 | |
| 3uce | NDP | Dehydrogenase | / | 0.443 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 4k81 | GTP | GTPase HRas | / | 0.443 | |
| 4l3l | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.443 | |
| 5cwa | 0GA | Anthranilate synthase component 1 | 4.1.3.27 | 0.443 | |
| 5kjf | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.443 | |
| 1bdl | IM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 1beu | IPL | Tryptophan synthase alpha chain | / | 0.442 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.442 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.442 | |
| 1hku | NAD | C-terminal-binding protein 1 | 1.1.1 | 0.442 | |
| 1kfb | IGP | Tryptophan synthase alpha chain | / | 0.442 | |
| 1me7 | RVP | Inosine-5'-monophosphate dehydrogenase | / | 0.442 | |
| 1qr6 | NAD | NAD-dependent malic enzyme, mitochondrial | 1.1.1.38 | 0.442 | |
| 1uxj | NAD | Malate dehydrogenase | / | 0.442 | |
| 1uyh | PU0 | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 2ceo | T44 | Thyroxine-binding globulin | / | 0.442 | |
| 2dbv | NDP | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.442 | |
| 2dfv | NAD | L-threonine 3-dehydrogenase | / | 0.442 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.442 | |
| 2pck | SAH | Diphthine synthase | / | 0.442 | |
| 2pmo | HMD | Protein kinase 7 | / | 0.442 | |
| 2qoc | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.442 | |
| 2zpa | ADP | tRNA(Met) cytidine acetyltransferase TmcA | / | 0.442 | |
| 3au8 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.442 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.442 | |
| 3mpt | 1GK | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 3nl6 | TPS | Uncharacterized protein | / | 0.442 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.442 | |
| 3rai | X85 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 4a31 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.442 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.442 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.442 | |
| 4l4a | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 4nvk | 2NY | Peroxidase | / | 0.442 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.442 | |
| 5fwn | NAP | Putative dehydrogenase | / | 0.442 | |
| 1cju | FOK | Adenylate cyclase type 2 | / | 0.441 | |
| 1cju | FOK | Adenylate cyclase type 5 | / | 0.441 | |
| 1cjv | DAD | Adenylate cyclase type 2 | / | 0.441 | |
| 1cjv | DAD | Adenylate cyclase type 5 | / | 0.441 | |
| 1g41 | ADP | ATP-dependent protease ATPase subunit HslU | / | 0.441 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.441 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 1z3c | SA8 | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.441 | |
| 1z7y | AA5 | Cysteine synthase 1 | 2.5.1.47 | 0.441 | |
| 2an9 | GDP | Guanylate kinase | 2.7.4.8 | 0.441 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 2hck | QUE | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.441 | |
| 2p54 | 735 | Peroxisome proliferator-activated receptor alpha | / | 0.441 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.441 | |
| 2qtv | GNP | Small COPII coat GTPase SAR1 | 3.6.5 | 0.441 | |
| 2y3p | SM8 | DNA gyrase subunit A | / | 0.441 | |
| 2yvw | EPU | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.441 | |
| 3a9w | NAD | NDP-sugar epimerase | / | 0.441 | |
| 3b2e | ADP | ATPase GET3 | / | 0.441 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 3ics | ADP | Coenzyme A disulfide reductase | / | 0.441 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.441 | |
| 3sdi | 3SD | Proteasome subunit beta type-5 | 3.4.25.1 | 0.441 | |
| 3sdi | 3SD | Proteasome subunit beta type-6 | 3.4.25.1 | 0.441 | |
| 3ska | 053 | Genome polyprotein | 2.7.7.48 | 0.441 | |
| 4a9r | RU5 | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.441 | |
| 4b3a | TAC | Tetracycline repressor protein class D | / | 0.441 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.441 | |
| 4h4y | NAP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.441 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.441 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.441 | |
| 4kky | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 4kwi | 1TJ | Reductase homolog | / | 0.441 | |
| 4pan | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.441 | |
| 4pzs | ACO | Histone acetyltransferase p300 | / | 0.441 | |
| 4r1l | ADP | Phenylacetate-coenzyme A ligase | / | 0.441 | |
| 4uz6 | SCR | Palmitoleoyl-protein carboxylesterase NOTUM | / | 0.441 | |
| 1coz | CTP | Glycerol-3-phosphate cytidylyltransferase | 2.7.7.39 | 0.440 | |
| 1equ | EQI | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 1j1c | ADP | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.440 | |
| 1k8y | 13P | Tryptophan synthase alpha chain | / | 0.440 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 1msm | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 1nvq | UCN | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 1os1 | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.440 | |
| 1u3d | FAD | Cryptochrome-1 | / | 0.440 | |
| 1u4o | NDD | L-lactate dehydrogenase | 1.1.1.27 | 0.440 | |
| 2a87 | FAD | Thioredoxin reductase | 1.8.1.9 | 0.440 | |
| 2ci0 | 1CM | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.440 | |
| 2dxv | SAH | Diphthine synthase | / | 0.440 | |
| 2q61 | SF1 | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 2xvd | AS6 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.440 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.440 | |
| 3acj | KSS | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.440 | |
| 3doc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.440 | |
| 3dv3 | MEK | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.440 | |
| 3f46 | I2C | 5,10-methenyltetrahydromethanopterin hydrogenase | 1.12.98.2 | 0.440 | |
| 3ge1 | ADP | Glycerol kinase | / | 0.440 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.440 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.440 | |
| 3nd1 | SAH | Precorrin-6A synthase (Deacetylating) | / | 0.440 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.440 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.440 | |
| 3tqa | NDP | Dihydrofolate reductase | / | 0.440 | |
| 4ajb | TAP | Isocitrate dehydrogenase [NADP] | 1.1.1.42 | 0.440 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.440 | |
| 4ehz | JAK | Tyrosine-protein kinase JAK1 | / | 0.440 | |
| 4gj3 | 0XP | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.440 | |
| 4iqg | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.440 | |
| 4jbo | WPH | Aurora kinase A | 2.7.11.1 | 0.440 | |
| 4jnk | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.440 | |
| 4loh | 1SY | Stimulator of interferon genes protein | / | 0.440 | |
| 4prv | ADP | DNA gyrase subunit B | / | 0.440 | |
| 4qe6 | JN3 | Bile acid receptor | / | 0.440 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.440 | |
| 4yqf | GDP | Septin-9 | / | 0.440 | |
| 5c8w | PCG | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.440 |