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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1b8oIMHPurine nucleoside phosphorylase2.4.2.1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
1b8oIMHPurine nucleoside phosphorylase2.4.2.11.000
1a9p9DIPurine nucleoside phosphorylase2.4.2.10.708
1fxuGU7Purine nucleoside phosphorylase2.4.2.10.651
1b8nIMGPurine nucleoside phosphorylase2.4.2.10.635
1a9sNOSPurine nucleoside phosphorylase2.4.2.10.623
1rt9IMHPurine nucleoside phosphorylase2.4.2.10.620
1rszDIHPurine nucleoside phosphorylase2.4.2.10.574
3bgsDIHPurine nucleoside phosphorylase2.4.2.10.551
1rr6IMHPurine nucleoside phosphorylase2.4.2.10.543
4eph0RKCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.522
1yryMSGPurine nucleoside phosphorylase2.4.2.10.521
1v453DGPurine nucleoside phosphorylase2.4.2.10.519
2a0wDIHPurine nucleoside phosphorylase2.4.2.10.513
2zevIPEGeranylgeranyl pyrophosphate synthase/0.512
1v3q2DIPurine nucleoside phosphorylase2.4.2.10.511
4earIM5Purine nucleoside phosphorylase2.4.2.10.506
1pwyAC2Purine nucleoside phosphorylase2.4.2.10.503
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.503
4bfuZVUPantothenate kinase2.7.1.330.495
1rfgGMPPurine nucleoside phosphorylase2.4.2.10.494
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.493
2cekN8TAcetylcholinesterase3.1.1.70.492
4bfvZVVPantothenate kinase2.7.1.330.492
2rehFADNitroalkane oxidase1.7.3.10.491
3k8o229Purine nucleoside phosphorylase2.4.2.10.488
3zv7NHGAcetylcholinesterase3.1.1.70.488
2oc4IMHPurine nucleoside phosphorylase2.4.2.10.486
4arbC57Acetylcholinesterase3.1.1.70.486
4b68NAPL-ornithine N(5)-monooxygenase/0.486
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.486
1fmjRTLRetinol dehydratase/0.485
2tplHPPTyrosine phenol-lyase4.1.99.20.485
3ekuCY9Actin-5C/0.485
1k27MTMS-methyl-5'-thioadenosine phosphorylase/0.484
1q83TZ5Acetylcholinesterase3.1.1.70.484
3h3qH13Collagen type IV alpha-3-binding protein/0.482
1rctNOSPurine nucleoside phosphorylase2.4.2.10.481
2g5w8PG12-oxophytodienoate reductase 31.3.1.420.481
3jypNADQuinate/shikimate dehydrogenase (NAD(+))/0.481
4oztP1AEcdysone receptor, putative/0.481
3px3T3QdTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase2.1.1.2350.480
2p4sDIHAGAP005945-PA/0.479
1umaIN2Prothrombin3.4.21.50.478
1gpnHUBAcetylcholinesterase3.1.1.70.477
1gw2FERPeroxidase C1A1.11.1.70.477
1kw6BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.477
4bv9NDPKetimine reductase mu-crystallin1.5.1.250.477
2bb3SAHCobalamin biosynthesis precorrin-6Y methylase (CbiE)/0.475
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.475
2rqfJH3Hemolymph juvenile hormone binding protein/0.474
2xufTZ4Acetylcholinesterase3.1.1.70.474
3dvaTPWPyruvate dehydrogenase E1 component subunit alpha1.2.4.10.474
3dvaTPWPyruvate dehydrogenase E1 component subunit beta1.2.4.10.474
3f03FMNPentaerythritol tetranitrate reductase/0.474
3jsxCC2NAD(P)H dehydrogenase [quinone] 11.6.5.20.474
3p74FMNPentaerythritol tetranitrate reductase/0.474
1bwkFMNNADPH dehydrogenase 11.6.99.10.473
1e66HUXAcetylcholinesterase3.1.1.70.473
1xddAAYIntegrin alpha-L/0.473
2fxuBIDActin, alpha skeletal muscle/0.473
3p8iFMNPentaerythritol tetranitrate reductase/0.473
3tjlFMNNADPH dehydrogenase/0.473
1eiiRTLRetinol-binding protein 2/0.472
1i7pFADNADH-cytochrome b5 reductase 31.6.2.20.472
1trgCB3Thymidylate synthase/0.472
1a9cGTPGTP cyclohydrolase 13.5.4.160.471
1vi2NADQuinate/shikimate dehydrogenase/0.471
3zoiM2WIsopenicillin N synthase1.21.3.10.471
1tkaN3TTransketolase 12.2.1.10.470
3fktSIIBeta-secretase 13.4.23.460.470
4m0f1YKAcetylcholinesterase3.1.1.70.470
1h61PDNPentaerythritol tetranitrate reductase/0.469
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.469
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.469
1x8lOXRRetinol dehydratase/0.468
2uxpCLMHTH-type transcriptional regulator TtgR/0.468
3fr5I4AFatty acid-binding protein, adipocyte/0.468
3wqmB29Diterpene synthase3.1.7.80.468
4a802ANMajor pollen allergen Bet v 1-A/0.468
4a81DXCMajor pollen allergen Bet v 1-A/0.468
4lh71X8DNA ligase/0.468
1fmlRTLRetinol dehydratase/0.467
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.467
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.467
1bk0ACVIsopenicillin N synthase1.21.3.10.466
1itzTPPTransketolase, chloroplastic2.2.1.10.466
1pf7IMHPurine nucleoside phosphorylase2.4.2.10.466
2j9fTHV2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial1.2.4.40.466
2j9fTHV2-oxoisovalerate dehydrogenase subunit beta, mitochondrial1.2.4.40.466
3gncQQQGlutaryl-CoA dehydrogenase/0.466
3nzpPLPArginine decarboxylase/0.466
3tqxPLP2-amino-3-ketobutyrate coenzyme A ligase/0.466
4bb3KKAIsopenicillin N synthase1.21.3.10.466
4hh4SAHCcbJ/0.466
4kp71UQ1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic1.1.1.2670.466
1h69ARHNAD(P)H dehydrogenase [quinone] 11.6.5.20.465
1w4lGL8Acetylcholinesterase3.1.1.70.465
2gyuHI6Acetylcholinesterase3.1.1.70.465
3nmpPYVAbscisic acid receptor PYL2/0.465
4ey6GNTAcetylcholinesterase3.1.1.70.465
4lxk1YTBeta-secretase 13.4.23.460.465
4twrNADNAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase/0.465
1votHUPAcetylcholinesterase3.1.1.70.464
2dshSAHDiphthine synthase/0.464
2xuoTZ4Acetylcholinesterase3.1.1.70.464
3dzkNMNADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.464
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.464
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.464
1nj6A5AProline--tRNA ligase/0.463
1obnASVIsopenicillin N synthase1.21.3.10.463
2h3wHC5Carnitine O-acetyltransferase2.3.1.70.463
3imgBZ2Pantothenate synthetase6.3.2.10.463
3jyoNADQuinate/shikimate dehydrogenase (NAD(+))/0.463
3qeoLLTDeoxycytidine kinase2.7.1.740.463
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.463
4zqcF6FTryptophan synthase alpha chain/0.463
5er0FADUncharacterized NAD(FAD)-dependent dehydrogenase/0.463
1h22E10Acetylcholinesterase3.1.1.70.462
1h50FMNPentaerythritol tetranitrate reductase/0.462
1hb1OCVIsopenicillin N synthase1.21.3.10.462
1npdNADQuinate/shikimate dehydrogenase/0.462
1paxDHQPoly [ADP-ribose] polymerase 12.4.2.300.462
2c20NADUDP-glucose 4-epimerase/0.462
3veu0GOBeta-secretase 13.4.23.460.462
4fweFADLysine-specific histone demethylase 1B10.462
4m5pFMNNADPH dehydrogenase/0.462
1vgqCAOFormyl-CoA:oxalate CoA-transferase/0.461
2hpvFMNFMN-dependent NADH-azoreductase1.70.461
2i65NADADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.461
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.461
2xiq5ADMethylmalonyl-CoA mutase, mitochondrial/0.461
4gutFADLysine-specific histone demethylase 1B10.461
4jtqNAPAldo-keto reductase family 1 member C2/0.461
5bnw12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.461
1ex75GPGuanylate kinase2.7.4.80.460
1h63FMNPentaerythritol tetranitrate reductase/0.460
1u65CP0Acetylcholinesterase3.1.1.70.460
1v2hGUNPurine nucleoside phosphorylase2.4.2.10.460
2j3qTFLAcetylcholinesterase3.1.1.70.460
3af1GDPPantothenate kinase2.7.1.330.460
3eksCY9Actin-5C/0.460
3p80P80Pentaerythritol tetranitrate reductase/0.460
3rbqGLY_ALA_GLY_ALA_DAOProtein unc-119 homolog A/0.460
3uxvGUNNADPH-dependent 7-cyano-7-deazaguanine reductase/0.460
4a3uFMNNADH:flavin oxidoreductase/NADH oxidase/0.460
1jdzFMBPurine nucleoside phosphorylase/0.459
1qtiGNTAcetylcholinesterase3.1.1.70.459
1sd1FMCS-methyl-5'-thioadenosine phosphorylase/0.459
2gfxPMN3-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.459
2jl1NAPTriphenylmethane reductase/0.459
4a862ANMajor pollen allergen Bet v 1-A/0.459
4a87NARMajor pollen allergen Bet v 1-A/0.459
1gc5ADPADP-dependent glucokinase2.7.1.1470.458
1kw8BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.458
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.458
1rz0FADPhenol 2-hydroxylase component B/0.458
2dxdANPNucleoside diphosphate kinase2.7.4.60.458
2ejzSAHDiphthine synthase/0.458
2g0bNLTLong-chain N-acyl amino acid synthase/0.458
2gjlFMNNitronate monooxygenase1.13.12.160.458
2qtaTDPPyruvate dehydrogenase E1 component1.2.4.10.458
2yp0OVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.458
3jyqNADQuinate/shikimate dehydrogenase (NAD(+))/0.458
4dpi0N1Beta-secretase 13.4.23.460.458
4l1xNAPAldo-keto reductase family 1 member C2/0.458
4y17LAETranscriptional regulator of ftsQAZ gene cluster/0.458
1eirBPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.457
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.457
2g25TDKPyruvate dehydrogenase E1 component1.2.4.10.457
2iviACWIsopenicillin N synthase1.21.3.10.457
2xuiTZ5Acetylcholinesterase3.1.1.70.457
3zkyWT4Isopenicillin N synthase1.21.3.10.457
4b4vL34Bifunctional protein FolD/0.457
4b67NAPL-ornithine N(5)-monooxygenase/0.457
4b7zQ4QAcetylcholinesterase3.1.1.70.457
4cjx9L9C-1-tetrahydrofolate synthase, cytoplasmic, putative/0.457
4tlaADPCircadian clock protein kinase KaiC2.7.11.10.457
4tlcAGSCircadian clock protein kinase KaiC2.7.11.10.457
7stdCRPScytalone dehydratase4.2.1.940.457
1h36R88Squalene--hopene cyclase4.2.1.1290.456
1h66RH1NAD(P)H dehydrogenase [quinone] 11.6.5.20.456
1rzuADPGlycogen synthase 12.4.1.210.456
2gv8NDPThiol-specific monooxygenase1.14.130.456
2npiATPmRNA cleavage and polyadenylation factor CLP1/0.456
3cmfPDN3-oxo-5-beta-steroid 4-dehydrogenase/0.456
3ske054Genome polyprotein2.7.7.480.456
3sqwANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.456
4a86H35Major pollen allergen Bet v 1-A/0.456
4c49HCYCorticosteroid-binding globulin/0.456
4i0h1BLBeta-secretase 13.4.23.460.456
4uugPXGBranched-chain amino acid aminotransferase, putative/0.456
1oj4CDM4-diphosphocytidyl-2-C-methyl-D-erythritol kinase2.7.1.1480.455
1qorNDPQuinone oxidoreductase 1/0.455
2e8uIPEGeranylgeranyl pyrophosphate synthase/0.455
2gs9SAHUncharacterized protein/0.455
2r8pT6FTransketolase 1/0.455
2wezZYEBeta-secretase 13.4.23.460.455
2xlpFADPutative flavin-containing monooxygenase/0.455
2z4y252Geranylgeranyl pyrophosphate synthase/0.455
3cid318Beta-secretase 13.4.23.460.455
4bfxZVXPantothenate kinase2.7.1.330.455
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.455
4geb0LDKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.455
4wdb2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.455
5c1d12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.455
1cnfFADNitrate reductase [NADH]1.7.1.10.454
1k7fIAVTryptophan synthase alpha chain/0.454
2gmuPDGPutative pyridoxamine 5-phosphate-dependent dehydrase/0.454
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.454
3eu5GBOProtein farnesyltransferase subunit beta2.5.1.580.454
3fhxPLPPyridoxal kinase2.7.1.350.454
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.454
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.454
3sff0DIHistone deacetylase 83.5.1.980.454
4cf6CBDNAD(P)H dehydrogenase [quinone] 11.6.5.20.454
4e2dFMNDehydrogenase/0.454
4g8jTHMUridine phosphorylase/0.454
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.454
5e5h0T1Succinyl-CoA:acetate CoA-transferase/0.454
1gky5GPGuanylate kinase2.7.4.80.453
1hb3SCVIsopenicillin N synthase1.21.3.10.453
1odcA8BAcetylcholinesterase3.1.1.70.453
1q84TZ4Acetylcholinesterase3.1.1.70.453
1r5hAO2Methionine aminopeptidase 2/0.453
1rkwPNTHTH-type transcriptional regulator QacR/0.453
1zgcA2EAcetylcholinesterase3.1.1.70.453
2a58RBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.453
2a59LMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.453
2bu9HFVIsopenicillin N synthase1.21.3.10.453
2jf0HBPAcetylcholinesterase3.1.1.70.453
2ji9TPWOxalyl-CoA decarboxylase4.1.1.80.453
2r5nTPPTransketolase 1/0.453
2wvlGDDMannosyl-3-phosphogylcerate synthase/0.453
2xukTZ5Acetylcholinesterase3.1.1.70.453
3fun798Leukotriene A-4 hydrolase3.3.2.60.453
3g1rFIT3-oxo-5-beta-steroid 4-dehydrogenase/0.453
3h3r14HCollagen type IV alpha-3-binding protein/0.453
3uzxAOM3-oxo-5-beta-steroid 4-dehydrogenase/0.453
4fqsLYAThymidylate synthase ThyA/0.453
4qaiFMNNADPH dehydrogenase/0.453
4rvnCOAPhenylacetate-coenzyme A ligase/0.453
1dmyAZMCarbonic anhydrase 5A, mitochondrial4.2.1.10.452
1gaxVAAValine--tRNA ligase6.1.1.90.452
1tilATPAnti-sigma F factor/0.452
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.452
2qimZEAClass 10 plant pathogenesis-related protein/0.452
2weyEV1cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.452
2xuhTZ4Acetylcholinesterase3.1.1.70.452
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.452
3k8q22APurine nucleoside phosphorylase2.4.2.10.452
3r1kCOAN-acetyltransferase Eis/0.452
4a6rTA8Probable aminotransferase/0.452
4rr7A3SProbable threonine--tRNA ligase 26.1.1.30.452
4x28FDAAcyl-CoA dehydrogenase FadE26/0.452
4x28FDAAcyl-CoA dehydrogenase FadE27/0.452
1w6rGNTAcetylcholinesterase3.1.1.70.451
2e0nSAHPrecorrin-2 C20-methyltransferase/0.451
2hxzH7JCathepsin S3.4.22.270.451
2jn3JN3Fatty acid-binding protein, liver/0.451
2vn1FK5Peptidylprolyl isomerase/0.451
2xi4AFTAcetylcholinesterase3.1.1.70.451
3b1dPLSBetaC-S lyase/0.451
3gxfIFMGlucosylceramidase3.2.1.450.451
4b4w9L9Bifunctional protein FolD/0.451
4cdmFO1Deoxyribodipyrimidine photolyase/0.451
1mrqSTRAldo-keto reductase family 1 member C1/0.450
1pqc444Oxysterols receptor LXR-beta/0.450
1ygjRMCPyridoxal kinase2.7.1.350.450
2a2cADPN-acetylgalactosamine kinase2.7.1.1570.450
2ea4F79Methionine aminopeptidase 2/0.450
2g28TDKPyruvate dehydrogenase E1 component1.2.4.10.450
2v0uFMNNPH1-1/0.450
3ey9TDPPyruvate dehydrogenase [ubiquinone]1.2.5.10.450
3fazNOSPurine nucleoside phosphorylase/0.450
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.450
3ntrNADInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase1.1.1.180.450
3pzcGAPAmino acid--[acyl-carrier-protein] ligase 16.2.1.n20.450
3q9bB3NAcetylpolyamine amidohydrolase/0.450
4awsFMNNADH:flavin oxidoreductase Sye1/0.450
1f8gNADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.449
1h60STRPentaerythritol tetranitrate reductase/0.449
1icsFMN12-oxophytodienoate reductase 11.3.1.420.449
1q20PLOSulfotransferase family cytosolic 2B member 12.8.2.20.449
1r2jFADFkbI/0.449
1y2bDEEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.449
2b58COADiamine acetyltransferase 1/0.449
2jgsBTNAvidin/0.449
2rd2QSIGlutamine--tRNA ligase6.1.1.180.449
2vb8TLM3-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.449
2w6cBM4Acetylcholinesterase3.1.1.70.449
3c3xNAPEugenol synthase 11.1.1.3180.449
3hbfMYCFlavonoid 3-O-glucosyltransferase2.4.10.449
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.449
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.449
4acuQN7Beta-secretase 13.4.23.460.449
4awtFMNNADH:flavin oxidoreductase Sye1/0.449
4bfwZVWPantothenate kinase2.7.1.330.449
4ge90L0Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.449
4j0v1H7Beta-secretase 13.4.23.460.449
4wecNADShort chain dehydrogenase/0.449
4zzi1NSNAD-dependent protein deacetylase sirtuin-13.5.10.449
1oklMNSCarbonic anhydrase 24.2.1.10.448
1qbqHFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.448
1qbqHFPProtein farnesyltransferase subunit beta2.5.1.580.448
1r5gAO1Methionine aminopeptidase 2/0.448
1xtrGNPGTP-binding protein Rheb/0.448
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.448
2f99AKVAklanonic acid methyl ester cyclase AcmA5.5.1.230.448
2gouFMNNADH:flavin oxidoreductase Sye1/0.448
2hr8SAHDiphthine synthase/0.448
2yphQQY2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.448
3buvNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.448
3kej3EJCollagenase 33.4.240.448
3pkeY10Methionine aminopeptidase 2/0.448
4bftZVTPantothenate kinase2.7.1.330.448
4df2FMNNADPH dehydrogenase/0.448
4e32DWNMethyltransferase/0.448
4gg1TZDBenzoylformate decarboxylase4.1.1.70.448
4phlPILPhosphodiesterase/0.448
1eveE20Acetylcholinesterase3.1.1.70.447
1rsgFADPolyamine oxidase FMS1/0.447
1ve3SAMUncharacterized protein/0.447
2a0xDIHPurine nucleoside phosphorylase2.4.2.10.447
2a2sGSNGlutathione S-transferase P2.5.1.180.447
2c9zQUEAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.447
2emuSAHDiphthine synthase/0.447
2gywOBIAcetylcholinesterase3.1.1.70.447
2q92B23Methionine aminopeptidase/0.447
2vqqTFGHistone deacetylase 43.5.1.980.447
2wnbC5PCMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 12.4.99.40.447
2zshGA3Gibberellin receptor GID1A30.447
2zsiGA4Gibberellin receptor GID1A30.447
3aezGDPPantothenate kinase2.7.1.330.447
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.447
3exhTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.447
3exhTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.447
3i0pNADMalate dehydrogenase, putative/0.447
3o76GTBGlutathione S-transferase P 12.5.1.180.447
3p62FMNPentaerythritol tetranitrate reductase/0.447
3uzxAOX3-oxo-5-beta-steroid 4-dehydrogenase/0.447
4exg916Beta-secretase 13.4.23.460.447
4j7hTRHPCZA361.3/0.447
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.447
1ahgTYR_PLPAspartate aminotransferase2.6.1.10.446
1j78VDYVitamin D-binding protein/0.446
1mrkFMCRibosome-inactivating protein alpha-trichosanthin3.2.2.220.446
1t8xPEP2-dehydro-3-deoxyphosphooctonate aldolase2.5.1.550.446
1ulbGUNPurine nucleoside phosphorylase2.4.2.10.446
1umkFADNADH-cytochrome b5 reductase 31.6.2.20.446
2dsgSAHDiphthine synthase/0.446
2hdjNDPAldo-keto reductase family 1 member C2/0.446
2igqSAHHistone-lysine N-methyltransferase EHMT1/0.446
2nmtMIMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.446
2uxoTACHTH-type transcriptional regulator TtgR/0.446
3af0GDPPantothenate kinase2.7.1.330.446
3c1oNAPEugenol synthase/0.446
3g1rNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.446
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.446
3p84FMNPentaerythritol tetranitrate reductase/0.446
3v2uATPProtein GAL3/0.446
3vri1KXHLA class I histocompatibility antigen, B-57 alpha chain/0.446
4jicFMNGTN Reductase/0.446
4n4v2GYTankyrase-12.4.2.300.446
4tjy3GNTankyrase-22.4.2.300.446
4tlbAGSCircadian clock protein kinase KaiC2.7.11.10.446
1dx6GNTAcetylcholinesterase3.1.1.70.445
1nw4IMHPurine nucleoside phosphorylase/0.445
1u1f183Uridine phosphorylase2.4.2.30.445
1yw7A41Methionine aminopeptidase 2/0.445
1zgbA1EAcetylcholinesterase3.1.1.70.445
2abaSTRPentaerythritol tetranitrate reductase/0.445
2oz57XYUncharacterized protein/0.445
2p99YE6Methionine aminopeptidase/0.445
2rlcCHDCholoylglycine hydrolase3.5.1.240.445
2zdv37UProthrombin3.4.21.50.445
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.445
3nx2FERFerulic acid decarboxylase/0.445
3qgi33FGenome polyprotein2.7.7.480.445
3vjkM51Dipeptidyl peptidase 4/0.445
4b64NAPL-ornithine N(5)-monooxygenase/0.445
5dp2NAPCurF/0.445
1b2lNDCAlcohol dehydrogenase1.1.1.10.444
1icqOPD12-oxophytodienoate reductase 11.3.1.420.444
1mczRMNBenzoylformate decarboxylase4.1.1.70.444
2ckmAA7Acetylcholinesterase3.1.1.70.444
2iyaZIOOleandomycin glycosyltransferase/0.444
2v16C47Renin3.4.23.150.444
2vijC44Beta-secretase 13.4.23.460.444
2xupTZ5Acetylcholinesterase3.1.1.70.444
3atyFMNProstaglandin F2a synthase/0.444
3cic316Beta-secretase 13.4.23.460.444
3h3t16HCollagen type IV alpha-3-binding protein/0.444
3in6FMNUncharacterized protein/0.444
3ou2SAHSAM-dependent methyltransferase/0.444
3vg10GTBeta-secretase 13.4.23.460.444
4briUNPEctonucleoside triphosphate diphosphohydrolase I/0.444
4q0kGA3Phytohormone-binding protein/0.444
4qfyDCPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.444
4twnB96Ephrin type-A receptor 32.7.10.10.444
4x7uZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.444
1h51FMNPentaerythritol tetranitrate reductase/0.443
1icpFMN12-oxophytodienoate reductase 11.3.1.420.443
1je1GMPPurine nucleoside phosphorylase/0.443
1jf0CZHObelin/0.443
1m9hNAD2,5-diketo-D-gluconic acid reductase A1.1.1.3460.443
1nj5P5AProline--tRNA ligase/0.443
1qx4FADNADH-cytochrome b5 reductase 31.6.2.20.443
1txtCAAHMG-CoA synthase/0.443
1zisINI6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.443
2cbrA80Cellular retinoic acid-binding protein 1/0.443
2dg9RAPPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.443
2fj1CTCTetracycline repressor protein class D/0.443
2geuCOKPantothenate kinase2.7.1.330.443
2o6hINI6,7-dimethyl-8-ribityllumazine synthase 12.5.1.780.443
2oegUPGUDP-glucose pyrophosphorylase/0.443
2stdCRPScytalone dehydratase4.2.1.940.443
2y8lADP5'-AMP-activated protein kinase subunit gamma-1/0.443
3b9lAZZSerum albumin/0.443
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.443
3ggs2FDPurine nucleoside phosphorylase2.4.2.10.443
3lqsPSZD-alanine aminotransferase2.6.1.210.443
3opxU5PSuppressor of disruption of TFIIS/0.443
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.443
3sxjSAMPutative methyltransferase/0.443
4dbc3QPAspartate aminotransferase2.6.1.10.443
4fm80UQBeta-secretase 13.4.23.460.443
4j531J4Serine/threonine-protein kinase PLK12.7.11.210.443
4psbGA3Cytokinin-specific binding protein/0.443
4qzuRTLRetinol-binding protein 2/0.443
4tmcFMNOld yellow enzyme/0.443
1ay0TPPTransketolase 12.2.1.10.442
1bx1FADFerredoxin--NADP reductase, chloroplastic1.18.1.20.442
1me6IVSPlasmepsin-23.4.23.390.442
1ndhFADNADH-cytochrome b5 reductase 31.6.2.20.442
1o6qR17Squalene--hopene cyclase4.2.1.1290.442
1oycFMNNADPH dehydrogenase 11.6.99.10.442
1pq944BOxysterols receptor LXR-beta/0.442
1y2k7DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.442
2a57CRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.442
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.442
2v59LZKBiotin carboxylase6.3.4.140.442
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
3ibqATPPyridoxal kinase/0.442
3lpiZ74Beta-secretase 13.4.23.460.442
3uptTPPTransketolase/0.442
4b66NAPL-ornithine N(5)-monooxygenase/0.442
4c72TLG3-oxoacyl-ACP synthase/0.442
4drkI63Peptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.442
4esoNAPPutative oxidoreductase/0.442
4eywL0RCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.442
4k28NADShikimate dehydrogenase family protein/0.442
4m9aFDAAcyl-CoA dehydrogenase/0.442
4oe4NADDelta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial1.2.1.880.442
4tmbFMNOld yellow enzyme/0.442
4yj2GTPTubulin alpha-1B chain/0.442
1cg6MTAS-methyl-5'-thioadenosine phosphorylase/0.441
1gg5E09NAD(P)H dehydrogenase [quinone] 11.6.5.20.441
1nqvLMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.441
1w19T5P6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.441
2a0yDIHPurine nucleoside phosphorylase2.4.2.10.441
2b3vACODiamine acetyltransferase 1/0.441
2bktRPFRenin3.4.23.150.441
2ct8MSPMethionine--tRNA ligase6.1.1.100.441
2gqg1N1Tyrosine-protein kinase ABL12.7.10.20.441
2p9cNAID-3-phosphoglycerate dehydrogenase1.1.1.950.441
2q3rFMN12-oxophytodienoate reductase 11.3.1.420.441
3apwDP0Alpha-1-acid glycoprotein 2/0.441
3gkaFMNN-ethylmaleimide reductase/0.441
3h06VBPGlutamate receptor 2/0.441
3mjrAC2Deoxycytidine kinase2.7.1.740.441
4a2zVIQGlycylpeptide N-tetradecanoyltransferase/0.441
4a8v2ANMajor pollen allergen Bet v 1-J/0.441
4araC56Acetylcholinesterase3.1.1.70.441
4c36ZO9cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
4k4eK4ETankyrase-12.4.2.300.441
4nbwNADShort-chain dehydrogenase/reductase SDR/0.441
4rnvFMNNADPH dehydrogenase 11.6.99.10.441
4uy6SAHHistidine N-alpha-methyltransferase/0.441
4wfr2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.441
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.441
1cjwCOTSerotonin N-acetyltransferase/0.440
1kt8ILPBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.440
1x1cSAHC-20 methyltransferase/0.440
2emrSAHDiphthine synthase/0.440
2gjnFMNNitronate monooxygenase1.13.12.160.440
2pnjCHDFerrochelatase, mitochondrial4.99.1.10.440
3dopNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.440
3hgoFMN12-oxophytodienoate reductase 31.3.1.420.440
3ho9N3A3-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.440
3ko8NADNAD-dependent epimerase/dehydratase/0.440
3n71SFGHistone-lysine N-methyltransferase Smyd1/0.440
3pvcFADtRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC/0.440
3vyfVYFRenin3.4.23.150.440
4do30LAFatty-acid amide hydrolase 13.5.1.990.440
4fhd0TTSpore photoproduct lyase/0.440
4gdcNDPUDP-galactopyranose mutase/0.440
4imfSI3N-acetylneuraminate lyase/0.440
4l5aTBNS-methyl-5'-thioadenosine phosphorylase/0.440
4ms1381Gamma-aminobutyric acid type B receptor subunit 1/0.440