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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4rzuADPProbable thymidylate kinase2.7.4.9

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
4rzuADPProbable thymidylate kinase2.7.4.91.000
2henADPEphrin type-B receptor 22.7.10.10.528
3w8rACPUridine kinase/0.524
3td7FADProbable FAD-linked sulfhydryl oxidase R5961.8.3.20.509
3o15IFPThiamine-phosphate synthase/0.507
2qocANPEphrin type-A receptor 32.7.10.10.502
4ivgANPTNF receptor-associated protein 1/0.501
3h23B54Dihydropteroate synthase/0.499
2zshGA3Gibberellin receptor GID1A30.498
4ffrATPUncharacterized protein/0.497
2qo7ANPEphrin type-A receptor 32.7.10.10.496
4fryNADPutative signal-transduction protein with CBS domains/0.496
3eblGA4Gibberellin receptor GID1/0.493
4gp6ADPMetallophosphoesterase/0.493
5djuFMNNPH1-2/0.492
2q0cCTPPoly(A) polymerase, putative/0.491
2w02ATPAcsD/0.491
2z52H23Geranylgeranyl pyrophosphate synthase/0.491
3allFAD2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase/0.491
4m2aUPGUDP-glucose pyrophosphorylase/0.489
1p7cT5AThymidine kinase/0.488
5k5zANPUncharacterized protein/0.488
3ef5DGTProbable pyrophosphohydrolase/0.487
2w03ADNAcsD/0.486
2w2lNADD-mandelate dehydrogenase/0.486
4yp12BAStimulator of interferon genes protein/0.485
1ih8APCNH(3)-dependent NAD(+) synthetase6.3.1.50.484
3qttANPPantothenate synthetase/0.483
4o6mC5PUncharacterized protein/0.483
5k2bZMAAdenosine receptor A2a/0.483
1esvLARActin, alpha skeletal muscle/0.482
1kvtUPGUDP-glucose 4-epimerase5.1.3.20.482
2xrwANPMitogen-activated protein kinase 82.7.11.240.482
4ipeANPTNF receptor-associated protein 1/0.482
4xj3GTPCyclic GMP-AMP synthase/0.482
1lrjUD1UDP-glucose 4-epimerase5.1.3.20.480
1zaoATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.480
2wvjTTPThymidine kinase, cytosolic2.7.1.210.479
2x3jATPAcsD/0.479
1jpaANPEphrin type-B receptor 22.7.10.10.478
3ed1GA3Gibberellin receptor GID1/0.478
4zrnUPGUDP-glucose 4-epimerase, putative/0.478
1ci7UMPThymidylate synthase2.1.1.450.477
1z7eUGABifunctional polymyxin resistance protein ArnA/0.476
2xdoFADTetX family tetracycline inactivation enzyme/0.476
4dqwATPInosine-5'-monophosphate dehydrogenase/0.476
1zotEMABifunctional hemolysin/adenylate cyclase4.6.1.10.475
1drtPCVClavaminate synthase 11.14.11.210.474
1i7lATPSynapsin-2/0.474
2p2fCOAAcetyl-coenzyme A synthetase/0.474
5fkoTDCTetracycline repressor protein class D/0.474
5idwNAPShort-chain dehydrogenase/reductase SDR/0.474
1dxyNADD-2-hydroxyisocaproate dehydrogenase1.1.10.473
3ryhGTPTubulin alpha chain/0.473
4jdaA9SAbscisic acid receptor PYL3/0.473
4xsrUPGAlr3699 protein/0.473
1hpuA12Protein UshA3.1.3.50.472
3i0aDBHNeutrophil gelatinase-associated lipocalin/0.472
3r6c17NAnthranilate phosphoribosyltransferase/0.472
3uwqU5POrotidine 5'-phosphate decarboxylase/0.472
4dh5ADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.472
5a65TPPThiamine-triphosphatase3.6.1.280.472
3lgxATPD-alanine--poly(phosphoribitol) ligase subunit 1/0.471
3tdwGDPGentamicin resistance protein/0.471
4iazADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.471
4loh1SYStimulator of interferon genes protein/0.471
4qbfAP5Adenylate kinase/0.471
5c8yACPTubulin tyrosine ligase/0.471
2pz8APCNH(3)-dependent NAD(+) synthetase/0.470
3s1aATPCircadian clock protein kinase KaiC2.7.11.10.470
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.470
4jlpADPAdenylate kinase/0.470
4k10NI9Farnesyl pyrophosphate synthase/0.470
5eowFAD6-hydroxynicotinate 3-monooxygenase1.14.13.1140.470
2ptfFMNUncharacterized protein MTH_863/0.469
4xw5ATPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.469
1ht2ADPATP-dependent protease ATPase subunit HslU/0.468
1jedADPSulfate adenylyltransferase/0.468
1xmvADPProtein RecA/0.468
2p9kATPActin-related protein 2/0.468
2q7hYLYPyrrolysine--tRNA ligase/0.468
3iahNAPPutative oxoacyl-(Acyl carrier protein) reductase/0.468
3u9eCOALmo1369 protein/0.468
4a4zANPAntiviral helicase SKI23.6.4.130.468
4pl4ADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.468
5ayzNCNNicotinate-nucleotide pyrophosphorylase [carboxylating]2.4.2.190.468
5c3aURMHisto-blood group ABO system transferase/0.468
5cwa0GAAnthranilate synthase component 14.1.3.270.468
5iw5NMNNADH pyrophosphatase/0.468
1in5ADPHolliday junction ATP-dependent DNA helicase RuvB/0.467
2qoqANPEphrin type-A receptor 32.7.10.10.467
3wb2YGPUncharacterized protein MJ0488/0.467
4en4ATPPyridoxal kinase2.7.1.350.467
5c03AGSNon-receptor tyrosine-protein kinase TYK22.7.10.20.467
1equEQIEstradiol 17-beta-dehydrogenase 11.1.1.620.466
2z4zSC0Geranylgeranyl pyrophosphate synthase/0.466
3elbC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.466
3w2wATPCRISPR system Cmr subunit Cmr2/0.466
5cnsCDPRibonucleoside-diphosphate reductase 1 subunit alpha1.17.4.10.466
5iqeGNPBifunctional AAC/APH2.3.10.466
1cozCTPGlycerol-3-phosphate cytidylyltransferase2.7.7.390.465
1j39UPGDNA beta-glucosyltransferase/0.465
2olqATPPhosphoenolpyruvate carboxykinase (ATP)/0.465
3c4wATPRhodopsin kinase/0.465
1q3qANPThermosome subunit alpha/0.464
1vzbUMPThymidylate synthase/0.464
4b3aTACTetracycline repressor protein class D/0.464
4giu636Anthranilate phosphoribosyltransferase/0.464
1n38U3HRNA-directed RNA polymerase lambda-32.7.7.480.463
1udcUFMUDP-glucose 4-epimerase5.1.3.20.463
1v3sATPSignaling protein/0.463
2pb2PLPAcetylornithine/succinyldiaminopimelate aminotransferase2.6.1.110.463
3mx2TTPNucleoprotein/0.463
3rv9RVDSalicylate synthase/0.463
4ho9UTPGlucose-1-phosphate thymidylyltransferase/0.463
4lj9ACPChaperone protein ClpB/0.463
4wouGDPPhosphoenolpyruvate carboxykinase [GTP]/0.463
5cnsDATRibonucleoside-diphosphate reductase 1 subunit alpha1.17.4.10.463
5eoxADPType 4 fimbrial biogenesis protein PilM/0.463
1wc1TATAdenylate cyclase/0.462
2i14PCPNicotinate-nucleotide pyrophosphorylase/0.462
2xauADPPre-mRNA-splicing factor ATP-dependent RNA helicase PRP433.6.4.130.462
3c14GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short/0.462
3fjqATPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.462
3h5nATPMccB protein/0.462
3meyATPAmino acid--[acyl-carrier-protein] ligase 16.2.1.n20.462
4jlbADPAdenylate kinase/0.462
4r2lATPUniversal stress protein F/0.462
1h7wFMNDihydropyrimidine dehydrogenase [NADP(+)]1.3.1.20.461
2ft9CHDFatty acid-binding protein 2, liver/0.461
2qenADPWalker-Type ATPase/0.461
2rl1UD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.461
2xpvMIYTetracycline repressor protein class D/0.461
3apwDP0Alpha-1-acid glycoprotein 2/0.461
3lcmFADPutative oxidoreductase/0.461
3o153NMThiamine-phosphate synthase/0.461
4own5RGAnthranilate phosphoribosyltransferase/0.461
4qm6GTPMetallophosphoesterase/0.461
4zolGTPTubulin alpha-1B chain/0.461
1fnnADPORC1-type DNA replication protein/0.460
1t09NAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.460
2acxANPG protein-coupled receptor kinase 62.7.11.160.460
2q6bHR23-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.340.460
3attATPPutative aminoglycoside phosphotransferase2.7.10.460
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.460
3pjuC2EDiguanylate cyclase/phosphodiesterase/0.460
3qc9ADPRhodopsin kinase/0.460
3rv4ADPBiotin carboxylase6.3.4.140.460
3t2vKKJPeptidoglycan recognition protein 1/0.460
4h2nFAD2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase/0.460
4i9aNCNNicotinate-nucleotide pyrophosphorylase [carboxylating]/0.460
1k9sFM1Purine nucleoside phosphorylase DeoD-type/0.459
2r7pANPNon-structural protein 23.6.40.459
2vp4DCPDeoxynucleoside kinase/0.459
3vglANPGlucokinase/0.459
4h9tHL4Phosphotriesterase/0.459
4jsyGTPMetallophosphoesterase/0.459
4l7f1V5Mitogen-activated protein kinase 82.7.11.240.459
4nhyPD2Prolyl 3-hydroxylase OGFOD11.14.110.459
1h62ANBPentaerythritol tetranitrate reductase/0.458
1j7uANPAminoglycoside 3'-phosphotransferase2.7.1.950.458
1nzdUPGDNA beta-glucosyltransferase/0.458
1o01NADAldehyde dehydrogenase, mitochondrial1.2.1.30.458
1w5tADPORC1-type DNA replication protein 2/0.458
2hw1ANPKetohexokinase/0.458
2vaxCSCAcetyl-CoA--deacetylcephalosporin C acetyltransferase2.3.1.1750.458
3g6xDGTDNA polymerase iota2.7.7.70.458
3qw4U5POrotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative/0.458
3ty3GGGHomoisocitrate dehydrogenase1.1.1.870.458
5esoISC2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.458
1auxAGSSynapsin-1/0.457
1gzuNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.457
1m0wANPGlutathione synthetase6.3.2.30.457
1towCRZFatty acid-binding protein, adipocyte/0.457
2yx6ADPUncharacterized protein/0.457
3r9iADPSeptum site-determining protein MinD/0.457
3ta0ATPNitrogen regulatory protein P-II (GlnB-3)/0.457
4e03ADPPlasmid partitioning protein ParF/0.457
4fxfATPPyruvate kinase PKM2.7.1.400.457
4mkgAP5Adenylate kinase/0.457
4v02ATPSite-determining protein/0.457
5eoyADPType 4 fimbrial biogenesis protein PilM/0.457
5ftcADPTPR domain protein/0.457
5kj6NAJAlcohol dehydrogenase E chain1.1.1.10.457
1nb6UTPGenome polyprotein2.7.7.480.456
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.456
1szgFNSCytochrome b2, mitochondrial1.1.2.30.456
2bi4NADLactaldehyde reductase1.1.1.770.456
2zt5B4PGlycine--tRNA ligase/0.456
3af0GDPPantothenate kinase2.7.1.330.456
3kmwATPIntegrin-linked protein kinase2.7.11.10.456
3wygGTPGTP-binding nuclear protein GSP1/CNR1/0.456
4hmvWUBPhenazine biosynthesis protein PhzG1.40.456
4u03GTPCyclic GMP-AMP synthase/0.456
4xb2NDP319aa long hypothetical homoserine dehydrogenase/0.456
5d2eNAPMlnE/0.456
1e4yAP5Adenylate kinase/0.455
1l7eNAINAD(P) transhydrogenase subunit alpha part 11.6.1.20.455
1w5sADPORC1-type DNA replication protein 2/0.455
2yvfNADFerredoxin reductase/0.455
3ortAGSSerine/threonine protein kinase/0.455
3s3tATPUniversal stress protein/0.455
4fx9COACoenzyme A disulfide reductase1.8.1.140.455
4nzoANPInositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2/0.455
4uofDATNucleoside diphosphate kinase/0.455
5c8rUPGHisto-blood group ABO system transferase/0.455
5uviZMAAdenosine receptor A2a/0.455
1fyfSSAThreonine--tRNA ligase6.1.1.30.454
1ju9NADAlcohol dehydrogenase E chain1.1.1.10.454
1korANPArgininosuccinate synthase/0.454
1p9wANPType II secretion system protein E/0.454
2nliFMNLactate oxidase/0.454
2vkvTDCTetracycline repressor protein class D/0.454
3gueUPGUTP-glucose-1-phosphate uridylyltransferase 2, putative/0.454
3jszUPGUncharacterized protein/0.454
3tr05GPGuanylate kinase/0.454
4c77N01Phenylacetone monooxygenase1.14.13.920.454
1b5dDCMDeoxycytidylate 5-hydroxymethyltransferase2.1.2.80.453
1f20NAPNitric oxide synthase, brain1.14.13.390.453
1h47C5P2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase4.6.1.120.453
1n95HFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.453
1n95HFPProtein farnesyltransferase subunit beta2.5.1.580.453
1njfAGSDNA polymerase III subunit tau2.7.7.70.453
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
2vbdV10Isopenicillin N synthase1.21.3.10.453
2z4sADPChromosomal replication initiator protein DnaA/0.453
3chwATPMajor actin/0.453
3h86AP5Adenylate kinase/0.453
3rucUD2UDP-N-acetylglucosamine 4-epimerase/0.453
3swqEPUUDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.453
3uu114BAnthranilate phosphoribosyltransferase/0.453
4f5dC2EStimulator of interferon genes protein/0.453
4orkGDPBifunctional AAC/APH2.3.10.453
4rdiATPtRNA threonylcarbamoyladenosine dehydratase6.10.453
5agaANPDNA polymerase theta/0.453
1e79ATPATP synthase subunit alpha, mitochondrial/0.452
1e79ATPATP synthase subunit beta, mitochondrial3.6.3.140.452
1ffuFADCarbon monoxide dehydrogenase medium chain/0.452
1kqcFMNOxygen-insensitive NAD(P)H nitroreductase/0.452
1njfADPDNA polymerase III subunit tau2.7.7.70.452
1qapNTMNicotinate-nucleotide pyrophosphorylase [carboxylating]2.4.2.190.452
2gqrADPPhosphoribosylaminoimidazole-succinocarboxamide synthase6.3.2.60.452
2p9cNAID-3-phosphoglycerate dehydrogenase1.1.1.950.452
2xfsJ01Uncharacterized protein/0.452
3af1GDPPantothenate kinase2.7.1.330.452
3cisATPUniversal stress protein Rv2623/0.452
3fhxPLPPyridoxal kinase2.7.1.350.452
3fzfATPHeat shock cognate 71 kDa protein/0.452
3nlwH4BNitric oxide synthase, brain1.14.13.390.452
3ruhUD6UDP-N-acetylglucosamine 4-epimerase/0.452
5iqiGNPBifunctional AAC/APH2.3.10.452
1oaaNAPSepiapterin reductase1.1.1.1530.451
1reoFADL-amino-acid oxidase1.4.3.20.451
1zgdNAPChalcone reductase/0.451
2x0rNADMalate dehydrogenase/0.451
2xb5I7TTetracycline repressor protein class D/0.451
2z7qACPRibosomal protein S6 kinase alpha-12.7.11.10.451
3g8dADPBiotin carboxylase6.3.4.140.451
5cpmFNRNADH:flavin oxidoreductase/0.451
5fklTDCTetracycline repressor protein class D/0.451
5iqhGNPBifunctional AAC/APH2.3.10.451
1a5uATPPyruvate kinase PKM2.7.1.400.450
1nm1ATPMajor actin/0.450
1y8qATPSUMO-activating enzyme subunit 26.3.20.450
1zp9ATPRIO-type serine/threonine-protein kinase Rio12.7.11.10.450
3hk1B64Fatty acid-binding protein, adipocyte/0.450
3otwCOAPhosphopantetheine adenylyltransferase/0.450
4ttaFMCPurine nucleoside phosphorylase DeoD-type/0.450
4xjxATPType I restriction enzyme EcoR124II R protein3.1.21.30.450
1be4PCGNucleoside diphosphate kinase A 22.7.4.60.449
1n2eAPCPantothenate synthetase6.3.2.10.449
1rj9GCPSignal recognition particle receptor FtsY/0.449
1taeNADDNA ligase/0.449
1tysTMPThymidylate synthase/0.449
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.449
2rghFADAlpha-Glycerophosphate Oxidase/0.449
2rl2UD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.449
2wzgUPGUncharacterized protein/0.449
3ivgFG5Pantothenate synthetase6.3.2.10.449
3o7lANPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
4loi1YCStimulator of interferon genes protein/0.449
4oi2ADPProtein clpf-1/0.449
4xgxADPFAD:protein FMN transferase/0.449
5ca0ACPTubulin tyrosine ligase/0.449
4z35ON9Lysophosphatidic acid receptor 1/0.449
1j21ATPArgininosuccinate synthase/0.448
2dqmBESAminopeptidase N3.4.11.20.448
2e2qADPATP-dependent hexokinase/0.448
2e91ZOLGeranylgeranyl pyrophosphate synthase/0.448
2oapANPType II secretion system protein (GspE-2)/0.448
2r2nKYNKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.448
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
2zs8ADPPantothenate kinase2.7.1.330.448
3bgxTMPThymidylate synthase/0.448
3cluFADElectron transfer flavoprotein subunit alpha/0.448
3froNHFGlgA glycogen synthase/0.448
3jq3ADPLombricine kinase/0.448
3lu1UD2UDP-N-acetylglucosamine 4-epimerase/0.448
3rv7RVBSalicylate synthase/0.448
4nu0AP5Adenylate kinase/0.448
4oviN01Phenylacetone monooxygenase1.14.13.920.448
4r1lADPPhenylacetate-coenzyme A ligase/0.448
5i4nATPTyrosine-protein kinase JAK2/0.448
1osfKOSHeat shock protein HSP 90-alpha/0.447
1vzaUMPThymidylate synthase/0.447
1xbtTTPThymidine kinase, cytosolic2.7.1.210.447
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.447
2j7t274Serine/threonine-protein kinase 102.7.11.10.447
2zu9GDPMannosyl-3-phosphoglycerate synthase2.4.1.2170.447
3c9sACPThiamine-monophosphate kinase/0.447
3fr5I4AFatty acid-binding protein, adipocyte/0.447
3keuATPPyridoxal kinase2.7.1.350.447
3lpfZ77Beta-glucuronidase3.2.1.310.447
3ntdCOAFAD-dependent pyridine nucleotide-disulphide oxidoreductase/0.447
3tlxADPAdenylate kinase 2/0.447
3vs2VSBTyrosine-protein kinase HCK2.7.10.20.447
3vtkADPThymidine kinase/0.447
4dyn0MRNucleoprotein/0.447
4ev0CMPCyclic AMP receptor protein/0.447
4fflADPUncharacterized protein/0.447
4fj0NAP17beta-hydroxysteroid dehydrogenase/0.447
4h2pFAD2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase/0.447
4iawLIZNeutrophil gelatinase-associated lipocalin/0.447
4jy2FAD2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase/0.447
4y9uNAPNADPH--cytochrome P450 reductase/0.447
5ccyTMPPolymerase acidic protein/0.447
1c80GTP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 13.1.3.460.446
1d7yFADFerredoxin reductase/0.446
1gjvAGS[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial2.7.11.40.446
1gwcGTXGlutathione S-transferase 1/0.446
1kp8AGS60 kDa chaperonin/0.446
1lrlUPGUDP-glucose 4-epimerase5.1.3.20.446
1n1dC2GGlycerol-3-phosphate cytidylyltransferase2.7.7.390.446
1ptjSNDNAD(P) transhydrogenase subunit alpha part 11.6.1.20.446
1sb8UD2WbpP/0.446
1w5tANPORC1-type DNA replication protein 2/0.446
1ytmATPPhosphoenolpyruvate carboxykinase (ATP)/0.446
2h2aDNDProbable nicotinate-nucleotide adenylyltransferase/0.446
2q3rFMN12-oxophytodienoate reductase 11.3.1.420.446
2qrdADP5'-AMP-activated protein kinase subunit gamma/0.446
2r8fAGSNon-structural protein 23.6.40.446
2vutNADNitrogen metabolite repression protein nmrA/0.446
2xvu9DNSerum albumin/0.446
2z50028Geranylgeranyl pyrophosphate synthase/0.446
2zseACPPantothenate kinase2.7.1.330.446
3crlANP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial2.7.11.20.446
3junAKDPhenazine biosynthesis protein A/B/0.446
3n82NADAldehyde dehydrogenase, mitochondrial1.2.1.30.446
3opxU5PSuppressor of disruption of TFIIS/0.446
3r1rATPRibonucleoside-diphosphate reductase 1 subunit alpha1.17.4.10.446
3sptUD1Bifunctional protein GlmU/0.446
3tdvGDPGentamicin resistance protein/0.446
4bzqADPBifunctional enzyme CysN/CysC2.7.1.250.446
4dya0MFNucleoprotein/0.446
4f48C2EUncharacterized protein/0.446
4gteFADFlavin-dependent thymidylate synthase2.1.1.1480.446
4j7gTRHPCZA361.3/0.446
1kh2ATPArgininosuccinate synthase/0.445
2dpxGDPGTP-binding protein RAD/0.445
2q3oFMN12-oxophytodienoate reductase 31.3.1.420.445
2qr1ADP5'-AMP-activated protein kinase subunit gamma/0.445
3almFAD2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase/0.445
3h9jAPCMccB protein/0.445
3jvhHHV2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase/0.445
3tlkEB4Ferrienterobactin-binding periplasmic protein/0.445
3tyeXTZDihydropteroate synthase/0.445
4a99FADTetX family tetracycline inactivation enzyme/0.445
4f6w0SSCyclin-dependent kinase 82.7.11.220.445
4fduIHSPutative multiple inositol polyphosphate histidine phosphatase 1/0.445
4je7BB2Peptide deformylase 1A, chloroplastic/mitochondrial3.5.1.880.445
4nauAGSPhosphopantetheine adenylyltransferase/0.445
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.445
4u07ATPAdenosine monophosphate-protein transferase FICD2.7.7.n10.445
4yvz3ATDNA integrity scanning protein DisA/0.445
1b5eDCMDeoxycytidylate 5-hydroxymethyltransferase2.1.2.80.444
1dliUDXUDP-glucose 6-dehydrogenase/0.444
1lolXMPOrotidine 5'-phosphate decarboxylase4.1.1.230.444
1px2ATPSynapsin-1/0.444
1yp4ADQGlucose-1-phosphate adenylyltransferase small subunit, chloroplastic/amyloplastic2.7.7.270.444
2i4n5CAProline--tRNA ligase6.1.1.150.444
2rkgAB1Pol protein/0.444
3fhyATPPyridoxal kinase2.7.1.350.444
3ogxH1SPeptidoglycan recognition protein 1/0.444
3q8xUD1Toxin zeta/0.444
3umpATPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.444
4kq2U5PGlycogen [starch] synthase isoform 22.4.1.110.444
4m69ANPReceptor-interacting serine/threonine-protein kinase 32.7.11.10.444
4mzuTYDWxcM-like protein/0.444
4oadCLMUncharacterized protein/0.444
4yp05IQHistidyl-tRNA synthetase, putative/0.444
5c1hGDUHisto-blood group ABO system transferase/0.444
1i3lGDUUDP-glucose 4-epimerase/0.443
1okkGCPSignal recognition particle protein/0.443
1okkGCPSignal recognition particle receptor FtsY/0.443
1ykiFMNOxygen-insensitive NAD(P)H nitroreductase/0.443
2e8wIPEGeranylgeranyl pyrophosphate synthase/0.443
2g8aUMPThymidylate synthase/0.443
2hu4G39Neuraminidase/0.443
2wvlGDDMannosyl-3-phosphogylcerate synthase/0.443
2x0iNAIMalate dehydrogenase/0.443
2x60GTPMannose-1-phosphate guanylyltransferase/0.443
3aljFAD2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase/0.443
3bosCDPRegulatory inactivation of DnaA Hda protein/0.443
3ekuATPActin-5C/0.443
3fccATPD-alanine--poly(phosphoribitol) ligase subunit 1/0.443
3g6wGTPUracil phosphoribosyltransferase2.4.2.90.443
3iocA5DPantothenate synthetase6.3.2.10.443
3ormAGSSerine/threonine protein kinase/0.443
3umoATPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.443
4dyp0MSNucleoprotein/0.443
4hys1BJMitogen-activated protein kinase 82.7.11.240.443
4ku2MYA3-oxoacyl-[ACP] synthase III/0.443
4nesUD1UDP-N-acetylglucosamine 2-epimerase5.1.3.140.443
4nl4ADPPrimosomal protein N'/0.443
4wrkDUPDUTPase/0.443
4y9xUPGGlucosyl-3-phosphoglycerate synthase2.4.1.2660.443
5d3fFSC14-3-3 protein zeta/delta/0.443
1je1GMPPurine nucleoside phosphorylase/0.442
1ny3ADPMAP kinase-activated protein kinase 22.7.11.10.442
2anb5GPGuanylate kinase2.7.4.80.442
2isc223Purine nucleoside phosphorylase, putative/0.442
2qc8ADPGlutamine synthetase6.3.1.20.442
2xszATPRuvB-like 23.6.4.120.442
3epoMP5Phosphomethylpyrimidine synthase/0.442
3h8gBESCytosol aminopeptidase3.4.11.10.442
3lliFADSulfhydryl oxidase 11.8.3.20.442
3lmgANPReceptor tyrosine-protein kinase erbB-32.7.10.10.442
3mw9NAIGlutamate dehydrogenase 1, mitochondrial1.4.1.30.442
4bjzFADProbable salicylate monooxygenase/0.442
4d7mTDCTetracycline repressor protein class D/0.442
4g2fC07Ephrin type-A receptor 32.7.10.10.442
4tl8AGSCircadian clock protein kinase KaiC2.7.11.10.442
4xhgADPUncharacterized protein/0.442
5k2aZMAAdenosine receptor A2a/0.442
1f3bGBXGlutathione S-transferase A12.5.1.180.441
1g9dBABBotulinum neurotoxin type B3.4.24.690.441
1i44ACPInsulin receptor2.7.10.10.441
1jdbADPCarbamoyl-phosphate synthase large chain/0.441
1kolNADGlutathione-independent formaldehyde dehydrogenase/0.441
1nlmUD1UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase/0.441
1nzfUPGDNA beta-glucosyltransferase/0.441
1qlhNADAlcohol dehydrogenase E chain1.1.1.10.441
1s3gAP5Adenylate kinase/0.441
1tsvUMPThymidylate synthase/0.441
1x31FMNSubunit alpha of sarocosine oxidase/0.441
1x31FMNSubunit beta of sarcosine oxidase/0.441
2c0oL2GTyrosine-protein kinase HCK2.7.10.20.441
2hmaSAMtRNA-specific 2-thiouridylase MnmA/0.441
2xyuQ9GEphrin type-A receptor 42.7.10.10.441
2zdyADP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial2.7.11.20.441
3b2eADPATPase GET3/0.441
3dm5GDPSignal recognition particle 54 kDa protein/0.441
3ndvAICBeta-peptidyl aminopeptidase BapA/0.441
3qs817DAnthranilate phosphoribosyltransferase/0.441
3uk6ADPRuvB-like 23.6.4.120.441
3v4tUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.441
4dyb0MHNucleoprotein/0.441
4fl3ANPTyrosine-protein kinase SYK2.7.10.20.441
4in44IDKelch-like ECH-associated protein 1/0.441
4ix5ANPUncharacterized protein/0.441
4j7uNAPSepiapterin reductase1.1.1.1530.441
4k33ACPFibroblast growth factor receptor 32.7.10.10.441
4k36SAMAnaerobic sulfatase-maturating enzyme1.8.980.441
4nm7ADPGlycogen synthase kinase-3 beta2.7.11.260.441
4p2lFADSulfhydryl oxidase 11.8.3.20.441
5fkmTDCTetracycline repressor protein class D/0.441
5iqdGNPBifunctional AAC/APH2.3.10.441
5l3rGCPCell division protein FtsY homolog, chloroplastic/0.441
1e8zSTUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
1orrCDPCDP-paratose 2-epimerase/0.440
1tw4CHDFatty acid-binding protein, liver/0.440
2rdn1PL1-deoxypentalenic acid 11-beta-hydroxylase1.14.11.350.440
2trtTACTetracycline repressor protein class D/0.440
2xtzGSPGuanine nucleotide-binding protein alpha-1 subunit/0.440
3cx6GDPGuanine nucleotide-binding protein subunit alpha-13/0.440
3ge1ADPGlycerol kinase/0.440
3qsaTA7Anthranilate phosphoribosyltransferase/0.440
4cpdNADAlcohol dehydrogenase/0.440
4eagATP5'-AMP-activated protein kinase subunit gamma-1/0.440
4fv3EK6Mitogen-activated protein kinase 12.7.11.240.440
4gapFADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.440
4j98ACPFibroblast growth factor receptor 2/0.440
4l03NAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.440
4qxr1YEStimulator of interferon genes protein/0.440
4x7wMVIMycinamicin III 3''-O-methyltransferase2.1.1.2370.440