sc-PDB

List of CHEMBLId :

This value allows a number of roughly comparable measures of half-maximal response concentration/potency/affinity to be compared on a negative logarithmic scale (e.g., an IC50 measurement of 1nM would have a pChEMBL value of 9).

Uniprot Annotation

Name:	RNA-directed RNA polymerase lambda-3
ID:	RDRP_REOVD
AC:	P0CK31
Organism:	Reovirus type 3
Reign:	Viruses
TaxID:	10886
EC Number:	2.7.7.48

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Chains:

Chain Name:	Percentage of Residues within binding site
A	100 %

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Ligand binding site composition:

B-Factor:	27.880
Number of residues:	30
Including
Standard Amino Acids:	27
Non Standard Amino Acids:	2
Water Molecules:	1
Cofactors:
Metals:	MN MN

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Cavity properties

Ligandability	Volume (Å3)
0.594	1613.250

% Hydrophobic	% Polar
26.57	73.43
According to VolSite

HET Code:	U3H
Formula:	C9H14N2O14P3
Molecular weight:	467.134 g/mol
DrugBank ID:	-
Buried Surface Area:	37.49 %
Polar Surface area:	283.79 Å2

Number of
H-Bond Acceptors:	14
H-Bond Donors:	4
Rings:	2
Aromatic rings:	0
Anionic atoms:	4
Cationic atoms:	1
Rule of Five Violation:	1
Rotatable Bonds:	8

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Mass center Coordinates

X	Y	Z
-7.8875	93.7069	17.0717

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