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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4o29SAHProtein-L-isoaspartate O-methyltransferase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4o29SAHProtein-L-isoaspartate O-methyltransferase/1.000
3lbfSAHProtein-L-isoaspartate O-methyltransferase2.1.1.770.573
1kr5SAHProtein-L-isoaspartate(D-aspartate) O-methyltransferase2.1.1.770.513
4tuvCPZCytochrome P450 1191.140.505
3cjtSAHRibosomal protein L11 methyltransferase2.1.10.503
1qaoSAMrRNA adenine N-6-methyltransferase2.1.1.1840.501
3b6zCO7Enoyl reductase LovC10.500
3pt6SAHDNA (cytosine-5)-methyltransferase 12.1.1.370.500
1sg9SAMRelease factor glutamine methyltransferase2.1.1.2970.499
1fwkADPHomoserine kinase2.7.1.390.493
4xcvNDPProbable hydroxyacid dehydrogenase protein/0.493
1eh4IC1Casein kinase I homolog 12.7.11.10.489
1h74AGSHomoserine kinase2.7.1.390.488
3mdmFJZCholesterol 24-hydroxylase/0.487
4c04SFGProtein arginine N-methyltransferase 6/0.487
3zh8C58Protein kinase C iota type2.7.11.130.482
5cwa0GAAnthranilate synthase component 14.1.3.270.482
1qanSAHrRNA adenine N-6-methyltransferase2.1.1.1840.481
1w1rZEACytokinin dehydrogenase 11.5.99.120.481
5bqfNAPProbable hydroxyacid dehydrogenase protein/0.481
5ifiPRXAcetyl-coenzyme A synthetase/0.481
3dmhSAMProbable ribosomal RNA small subunit methyltransferase/0.479
3sf6FDAGlutaryl-CoA dehydrogenase/0.479
2plwSAMRibosomal RNA methyltransferase, putative/0.478
2w2lNADD-mandelate dehydrogenase/0.478
1bsvNDPGDP-L-fucose synthase/0.477
2ph5NADHomospermidine synthase/0.477
4h8nNDPNADPH-dependent conjugated polyketone reductase C2/0.477
2givACOHistone acetyltransferase KAT8/0.475
2vprTDCTetracycline repressor protein class H/0.475
4yv2S4MSpermidine synthase, putative/0.475
5dstSAHProtein arginine N-methyltransferase 82.1.10.475
1f4fTP3Thymidylate synthase/0.474
5epeSAHUncharacterized protein/0.474
2fhyA37Fructose-1,6-bisphosphatase 13.1.3.110.473
2ivnANPtRNA N6-adenosine threonylcarbamoyltransferase/0.473
3c1y2BADNA integrity scanning protein DisA/0.473
3oibFDAPutative acyl-CoA dehydrogenase/0.473
4xiwAZMCarbonic anhydrase, alpha type/0.473
1fxsNAPGDP-L-fucose synthase/0.472
1xddAAYIntegrin alpha-L/0.472
2bgjFADNADPH:ferredoxin reductase/0.471
4bcaFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.471
4f9mFCMPeroxisome proliferator-activated receptor gamma/0.471
1rbyKEUTrifunctional purine biosynthetic protein adenosine-32.1.2.20.470
2wbdRO5Fructose-1,6-bisphosphatase 13.1.3.110.470
2x7hPFNProstaglandin reductase 310.470
3ekp478Gag-Pol polyprotein3.4.23.160.470
3f1kNAPUncharacterized oxidoreductase YciK10.470
3iaeD7KBenzaldehyde lyase/0.470
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.469
2jfgUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.469
4qi5FADCellobiose dehydrogenase/0.469
1h72ANPHomoserine kinase2.7.1.390.468
3ow3SMYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.468
3pb3SAH16S rRNA (adenine(1408)-N(1))-methyltransferase2.1.1.1800.468
3wmxNADNAD dependent epimerase/dehydratase/0.468
4jxrACOAcetyltransferase/0.468
4u7tSAHDNA (cytosine-5)-methyltransferase 3A2.1.1.370.468
4uyf73BBromodomain-containing protein 2/0.468
1h2bNAJNAD-dependent alcohol dehydrogenase/0.467
1yonA2R2-dehydropantoate 2-reductase1.1.1.1690.467
2wotZZGTGF-beta receptor type-12.7.11.300.467
3qd33Q53-phosphoinositide-dependent protein kinase 12.7.11.10.467
3zuyTCHTransporter/0.467
4oal245Cytokinin dehydrogenase 4/0.467
5bxySAHPutative RNA methylase family UPF0020/0.467
1bmfANPATP synthase subunit alpha, mitochondrial/0.466
1bmfANPATP synthase subunit beta, mitochondrial3.6.3.140.466
2ww4ADP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase2.7.1.1480.466
3bwjARXcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.466
3p2eSAH16S rRNA (adenine(1408)-N(1))-methyltransferase2.1.1.1800.466
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.466
4kbyC2EStimulator of interferon genes protein/0.466
4mxeACON-acetyltransferase ESCO12.3.10.466
1c1dNAIPhenylalanine dehydrogenase/0.465
1tj1FADBifunctional protein PutA1.5.5.20.465
1uyePU9Heat shock protein HSP 90-alpha/0.465
1v9nNDPMalate dehydrogenase1.1.1.370.465
1xe55FEPlasmepsin-23.4.23.390.465
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.465
2y05NAPProstaglandin reductase 1/0.465
3pt9SAHDNA (cytosine-5)-methyltransferase 12.1.1.370.465
3sdi3SDProteasome subunit beta type-53.4.25.10.465
3sdi3SDProteasome subunit beta type-63.4.25.10.465
3sw418KCyclin-dependent kinase 22.7.11.220.465
3t7sSAMUncharacterized protein/0.465
4b99R4LMitogen-activated protein kinase 72.7.11.240.465
4o701QKBromodomain-containing protein 4/0.465
5dbvCOAAldehyde Dehydrogenase/0.465
1u3dFADCryptochrome-1/0.464
1vq1SAMRelease factor glutamine methyltransferase2.1.1.2970.464
2gqpPA7Endoplasmin/0.464
2oz6CMPCyclic AMP receptor-like protein/0.464
2vd5BI8Myotonin-protein kinase2.7.11.10.464
3b895GP16S rRNA methylase/0.464
4o95245Cytokinin dehydrogenase 4/0.464
5hwqCAAHydroxymethylglutaryl-CoA synthase/0.464
1g63FMNEpidermin decarboxylase4.1.10.463
2xgs44PUncharacterized protein/0.463
3k2hLYABifunctional dihydrofolate reductase-thymidylate synthase/0.463
3lu8IQXSerum albumin/0.463
3mnrSD1Heat shock protein HSP 90-alpha/0.463
3sdkP3NProteasome subunit beta type-53.4.25.10.463
3sdkP3NProteasome subunit beta type-63.4.25.10.463
4jwpACOGCN5-related N-acetyltransferase/0.463
4mdhNADMalate dehydrogenase, cytoplasmic1.1.1.370.463
1nv8SAMRelease factor glutamine methyltransferase2.1.1.2970.462
1xkkFMMEpidermal growth factor receptor2.7.10.10.462
1zq9SAMProbable dimethyladenosine transferase/0.462
2f4bEHAPeroxisome proliferator-activated receptor gamma/0.462
2pg0FADAcyl-CoA dehydrogenase/0.462
3a1nNADNDP-sugar epimerase/0.462
3b70NAPEnoyl reductase LovC10.462
3d7kD7KBenzaldehyde lyase/0.462
3egvSAHRibosomal protein L11 methyltransferase2.1.10.462
3o6o94MHeat shock protein 83/0.462
3uagUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.462
3we45FIRibosomal protein S6 kinase beta-12.7.11.10.462
4bcrWY1Peroxisome proliferator-activated receptor alpha/0.462
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.462
4ure1PSCyclohexanol dehydrogenase/0.462
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.461
1ipeNDPTropinone reductase 21.1.1.2360.461
1k6pXN3Gag-Pol polyprotein3.4.23.160.461
1rx1NAPDihydrofolate reductase1.5.1.30.461
2o7pNAPRiboflavin biosynthesis protein RibD/0.461
3fpjSAMUncharacterized protein/0.461
3m6iNADL-arabinitol 4-dehydrogenase1.1.1.120.461
3qihNI7Gag-Pol polyprotein3.4.23.160.461
3qtsX46Cyclin-dependent kinase 22.7.11.220.461
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.461
3tm5SFGUncharacterized protein/0.461
3vglANPGlucokinase/0.461
4fc7NAPPeroxisomal 2,4-dienoyl-CoA reductase1.3.1.340.461
4l435FIRibosomal protein S6 kinase beta-12.7.11.10.461
4nxvGDPMitochondrial dynamics protein MID51/0.461
4z3dNDPCarbonyl reductase [NADPH] 11.1.1.1840.461
5fs7FADApoptosis-inducing factor 1, mitochondrial1.1.10.461
1k6tXN1Gag-Pol polyprotein3.4.23.160.460
1phhFADp-hydroxybenzoate hydroxylase/0.460
3ft8MOJHeat shock protein HSP 90-alpha/0.460
3i59N6RCRP-like cAMP-activated global transcriptional regulator/0.460
3kgaLX9MAP kinase-activated protein kinase 22.7.11.10.460
3kybFADUDP-galactopyranose mutase5.4.99.90.460
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.460
3stw2TDMethylketone synthase I/0.460
4e5nNADPhosphonate dehydrogenase1.20.1.10.460
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.460
4h3qANPMitogen-activated protein kinase 12.7.11.240.460
4nmdFDABifunctional protein PutA/0.460
5bp9SAHPutative methyltransferase protein/0.460
5br7FADUDP-galactopyranose mutase/0.460
1uaeUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.459
3i0pNADMalate dehydrogenase, putative/0.459
3mvm39PMitogen-activated protein kinase 14/0.459
3r6sCMPCRP-like cAMP-activated global transcriptional regulator/0.459
4kvzSAHPtnL protein/0.459
1rc4DDFDihydrofolate reductase1.5.1.30.458
1w2xRCPAcetyl-CoA carboxylase/0.458
1wvgAPRCDP-glucose 4,6-dehydratase4.2.1.450.458
2a94AP0L-lactate dehydrogenase1.1.1.270.458
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.458
2ibzUQ6Cytochrome b/0.458
2p2bPRXAcetyl-coenzyme A synthetase/0.458
2x4f16XMyosin light chain kinase family member 42.7.11.10.458
3clsFADElectron transfer flavoprotein subunit alpha/0.458
3gc8B45Mitogen-activated protein kinase 112.7.11.240.458
3nwxKVSGag-Pol polyprotein3.4.23.160.458
3pkpDTPGlucose-1-phosphate thymidylyltransferase2.7.7.240.458
3rf7NADIron-containing alcohol dehydrogenase/0.458
4dpwAGSMevalonate diphosphate decarboxylase/0.458
4h1m0YJProtein-tyrosine kinase 2-beta2.7.10.20.458
4ryvZEAProtein LlR18A/0.458
5ahsCOAAcyl-CoA dehydrogenase/0.458
5hwsNAP2-dehydropantoate 2-reductase/0.458
1crbRTLRetinol-binding protein 1/0.457
1nboNADGlyceraldehyde-3-phosphate dehydrogenase A, chloroplastic1.2.1.130.457
1tj2FADBifunctional protein PutA1.5.5.20.457
1xq6NAPUncharacterized protein At5g02240/0.457
2henADPEphrin type-B receptor 22.7.10.10.457
2j5xGSPADP-ribosylation factor 6/0.457
2xhd7T9Glutamate receptor 2/0.457
3i6oGR6Gag-Pol polyprotein3.4.23.160.457
3ntaFADFAD-dependent pyridine nucleotide-disulphide oxidoreductase/0.457
3qp0NI8Gag-Pol polyprotein3.4.23.160.457
3u78E67Lysine-specific demethylase 7A1.14.110.457
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.457
4geb0LDKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.457
4nwzFADFAD-dependent pyridine nucleotide-disulfide oxidoreductase/0.457
5dozNDPJamJ/0.457
5hsaFASAlcohol oxidase 11.1.3.130.457
1mg5NAIAlcohol dehydrogenase1.1.1.10.456
1q97ATPSerine/threonine-protein kinase SKY12.7.11.10.456
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.456
2xzwATPNitrogen regulatory protein P-II/0.456
3dmgSAHProbable ribosomal RNA small subunit methyltransferase/0.456
3ndvAICBeta-peptidyl aminopeptidase BapA/0.456
3p3zP3ZPutative cytochrome P450/0.456
3w0qANPHygromycin-B 4-O-kinase2.7.1.1630.456
4e5mNAPPhosphonate dehydrogenase1.20.1.10.456
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.456
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.456
4gllNADUDP-glucuronic acid decarboxylase 14.1.1.350.456
4jazSTLPeroxisome proliferator-activated receptor gamma/0.456
4nxwADPMitochondrial dynamics protein MID51/0.456
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.456
5e8jSAHmRNA cap guanine-N7 methyltransferase2.1.1.560.456
5e8wSTUTGF-beta receptor type-12.7.11.300.456
5hwrCOAHydroxymethylglutaryl-CoA synthase/0.456
1adcPADAlcohol dehydrogenase E chain1.1.1.10.455
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.455
1l3iSAHProbable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating)/0.455
1ojtFADDihydrolipoyl dehydrogenase/0.455
1pdhFASp-hydroxybenzoate hydroxylase/0.455
1ruoCMPcAMP-activated global transcriptional regulator CRP/0.455
2aa3AP0L-lactate dehydrogenase/0.455
2fy4COACholine O-acetyltransferase2.3.1.60.455
2fzwNADAlcohol dehydrogenase class-31.1.1.10.455
2hfpNSIPeroxisome proliferator-activated receptor gamma/0.455
2y8qADP5'-AMP-activated protein kinase subunit gamma-1/0.455
3cjqSAHRibosomal protein L11 methyltransferase2.1.10.455
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.455
3vrtYS2Vitamin D3 receptor/0.455
3zbnCOA3-ketoacyl-CoA thiolase-like protein/0.455
4a9e3PFBromodomain-containing protein 2/0.455
4e4qRRHPeroxisome proliferator-activated receptor gamma/0.455
5koiNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.455
6adhNADAlcohol dehydrogenase E chain1.1.1.10.455
1h74ADPHomoserine kinase2.7.1.390.454
1rf7DHFDihydrofolate reductase1.5.1.30.454
2cgpCMPcAMP-activated global transcriptional regulator CRP/0.454
2qo9ANPEphrin type-A receptor 32.7.10.10.454
2r43G3GGag-Pol polyprotein3.4.23.160.454
2zwvSAHProbable ribosomal RNA small subunit methyltransferase/0.454
3a4vNADNDP-sugar epimerase/0.454
3s1dZIRCytokinin dehydrogenase 11.5.99.120.454
3tm4SAMUncharacterized protein/0.454
3uj7SAMPhosphoethanolamine N-methyltransferase/0.454
3wbbNAPMeso-diaminopimelate D-dehydrogenase/0.454
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.454
4kcfAKMFAD-dependent oxidoreductase/0.454
4ng5PFBAlcohol dehydrogenase E chain1.1.1.10.454
4qmpDKISerine/threonine-protein kinase 242.7.11.10.454
4y95746Tyrosine-protein kinase/0.454
1dq8COA3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.340.453
1e3eNAIAlcohol dehydrogenase 41.1.1.10.453
1gqtACPRibokinase/0.453
1gufNDPEnoyl-[acyl-carrier-protein] reductase 1, mitochondrial1.3.1.100.453
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.453
1hb3SCVIsopenicillin N synthase1.21.3.10.453
1ia1NDPDihydrofolate reductase1.5.1.30.453
1iidNHMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.453
1kzjCB3Thymidylate synthase/0.453
1rbmKT5Trifunctional purine biosynthetic protein adenosine-32.1.2.20.453
1uy6PU3Heat shock protein HSP 90-alpha/0.453
1zmdNAIDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.453
2ath3EAPeroxisome proliferator-activated receptor gamma/0.453
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.453
2pmdGNPTranslation initiation factor 2 subunit gamma/0.453
2pr2DG1Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.453
2vkeTACTetracycline repressor protein class D/0.453
2xikJ60Serine/threonine-protein kinase 252.7.11.10.453
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.453
3grySAMProbable ribosomal RNA small subunit methyltransferase A/0.453
3ictCOACoenzyme A disulfide reductase/0.453
3qlsNDPDihydrofolate reductase1.5.1.30.453
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.453
3w0c6DSVitamin D3 receptor/0.453
4h3c0YZDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.453
4wuoNAD3-isopropylmalate dehydrogenase1.1.1.850.453
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.453
5br4NADLactaldehyde reductase1.1.1.770.453
5dqrFAD7-hydroxymethyl chlorophyll a reductase, chloroplastic1.17.7.20.453
5kjcPFBAlcohol dehydrogenase E chain1.1.1.10.453
1dg8NDPDihydrofolate reductase1.5.1.30.452
1ffuFADCarbon monoxide dehydrogenase medium chain/0.452
1hdrNADDihydropteridine reductase1.5.1.340.452
1qbu846Gag-Pol polyprotein3.4.23.160.452
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.452
2pkrNDPGlyceraldehyde-3-phosphate dehydrogenase A, chloroplastic1.2.1.130.452
2vo6M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.452
2ydxNAPMethionine adenosyltransferase 2 subunit beta/0.452
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.452
3anlNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.452
3p4tFAOPutative acyl-CoA dehydrogenase/0.452
3qlrNDPDihydrofolate reductase1.5.1.30.452
3r1sX73Cyclin-dependent kinase 22.7.11.220.452
3vspEK8Peroxisome proliferator-activated receptor gamma/0.452
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.452
4da4SAHDNA (cytosine-5)-methyltransferase 12.1.1.370.452
4is3NAD3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 21.17.98.10.452
1e5qNDPSaccharopine dehydrogenase [NADP(+), L-glutamate-forming]1.5.1.100.451
1ih8APCNH(3)-dependent NAD(+) synthetase6.3.1.50.451
1rdt570Peroxisome proliferator-activated receptor gamma/0.451
1rw8580TGF-beta receptor type-12.7.11.300.451
1vjy460TGF-beta receptor type-12.7.11.300.451
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.451
2he5NDPAldo-keto reductase family 1 member C211.1.10.451
2ix5FADAcyl-coenzyme A oxidase 4, peroxisomal1.3.3.60.451
2q29ACOOxalyl-CoA decarboxylase4.1.1.80.451
2vo7M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.451
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.451
3rpeFADPutative modulator of drug activity/0.451
3stxBKAMethylketone synthase I/0.451
3t4nADP5'-AMP-activated protein kinase subunit gamma/0.451
3uqdATPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.451
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.451
4bbyFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.451
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.451
4jx1CAHCamphor 5-monooxygenase1.14.15.10.451
4kin1M8Mitogen-activated protein kinase 14/0.451
4ly91YYGlucokinase regulatory protein/0.451
4n9wGDPPhosphatidyl-myo-inositol mannosyltransferase2.4.1.570.451
4o8aFADBifunctional protein PutA1.2.1.880.451
4yuzS4MSpermidine synthase, putative/0.451
1ke5LS1Cyclin-dependent kinase 22.7.11.220.450
1qf4RPDAdenylosuccinate synthetase/0.450
1qnfFADDeoxyribodipyrimidine photo-lyase4.1.99.30.450
1r2jFADFkbI/0.450
1rbyGARTrifunctional purine biosynthetic protein adenosine-32.1.2.20.450
1t7i017Gag-Pol polyprotein3.4.23.160.450
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.450
2qnqQN3Gag-Pol polyprotein3.4.23.160.450
2zb3NDPProstaglandin reductase 21.3.1.480.450
3drcMTXDihydrofolate reductase1.5.1.30.450
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.450
4awo99BHeat shock protein HSP 90-alpha/0.450
4ezj0SCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
4l2iFADElectron transfer flavoprotein alpha/beta-subunit/0.450
4rqvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.450
4u03GTPCyclic GMP-AMP synthase/0.450
4xqcNADHomospermidine synthase2.5.1.440.450
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.450
5eypLOCTubulin beta chain/0.450
5k2aZMAAdenosine receptor A2a/0.450
1ajvNMBGag-Pol polyprotein3.4.23.160.449
1kkq471Peroxisome proliferator-activated receptor alpha/0.449
1m2gAPRNAD-dependent protein deacylase 1/0.449
1menGARTrifunctional purine biosynthetic protein adenosine-32.1.2.20.449
2pv7NADT-protein1.3.1.120.449
2vv9IM9Cyclin-dependent kinase 22.7.11.220.449
2znpK55Peroxisome proliferator-activated receptor delta/0.449
3docNADGlyceraldehyde-3-phosphate dehydrogenase/0.449
3e8eG98cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
3gggNADPrephenate dehydrogenase/0.449
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
3n7uNADFormate dehydrogenase, chloroplastic/mitochondrial/0.449
3s1sSAHRestriction endonuclease BpuSI/0.449
3t14FADSulfide-quinone reductase/0.449
4cax646Glycylpeptide N-tetradecanoyltransferase2.3.1.970.449
4g6nEK0Mitogen-activated protein kinase 12.7.11.240.449
4jhz1KVBeta-glucuronidase3.2.1.310.449
4mwhATPCasein kinase II subunit alpha2.7.11.10.449
5hes032Mitogen-activated protein kinase kinase kinase 202.7.11.250.449
5itzLOCTubulin beta-2B chain/0.449
1bifAGS6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 42.7.1.1050.448
1hihC20Gag-Pol polyprotein/0.448
1hvsA77Gag-Pol polyprotein/0.448
1phePIYCamphor 5-monooxygenase1.14.15.10.448
1qvnFRIInterleukin-2/0.448
1rkxNADCDP-D-glucose-4,6-dehydratase/0.448
1tj0FADBifunctional protein PutA1.5.5.20.448
1ty8ADPProbable ADP-ribose 1''-phosphate phosphatase YML087W3.1.3.840.448
1wn3HXCPhenylacetic acid degradation protein PaaI/0.448
2du8FADD-amino-acid oxidase1.4.3.30.448
2fzmFADBifunctional protein PutA1.5.5.20.448
2gs9SAHUncharacterized protein/0.448
2tctCTCTetracycline repressor protein class D/0.448
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.448
2y8lADP5'-AMP-activated protein kinase subunit gamma-1/0.448
3bc3OPTCathepsin L13.4.22.150.448
3deyDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.448
3el4ROCGag-Pol polyprotein3.4.23.160.448
3friSAH16S rRNA methylase/0.448
3keuATPPyridoxal kinase2.7.1.350.448
3klmDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.448
3och2MXDihydrofolate reductase1.5.1.30.448
3t2zFADSulfide-quinone reductase/0.448
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.448
4c58824Cyclin-G-associated kinase2.7.11.10.448
4fcr0TMHeat shock protein HSP 90-alpha/0.448
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.448
4g6hNAIRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.448
4i6gFADCryptochrome-2/0.448
4nxuADPMitochondrial dynamics protein MID51/0.448
5ca1NZOTubulin beta-2 chain/0.448
5hs1VORLanosterol 14-alpha demethylase/0.448
1adfTADAlcohol dehydrogenase E chain1.1.1.10.447
1bwsNDPGDP-L-fucose synthase/0.447
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.447
1izhQ50Protease/0.447
1nv9SAHRelease factor glutamine methyltransferase2.1.1.2970.447
1oc1ASVIsopenicillin N synthase1.21.3.10.447
1pg3PRXAcetyl-coenzyme A synthetase/0.447
2bifANP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 42.7.1.1050.447
2g5cNADPrephenate dehydrogenase/0.447
2h55DZ8Heat shock protein HSP 90-alpha/0.447
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.447
2ijmATPFocal adhesion kinase 12.7.10.20.447
2np7NEAModification methylase TaqI2.1.1.720.447
3bgcLJHGag-Pol polyprotein3.4.23.160.447
3cgeCOACoenzyme A disulfide reductase/0.447
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.447
3kb6NADD-lactate dehydrogenase/0.447
3nwq2NCGag-Pol polyprotein3.4.23.160.447
3oqkS52Renin3.4.23.150.447
3tvuB37Acetyl-CoA carboxylase/0.447
3w8eNAD3-hydroxybutyrate dehydrogenase/0.447
3zkyWT4Isopenicillin N synthase1.21.3.10.447
4d0l093Phosphatidylinositol 4-kinase beta2.7.1.670.447
4i13FOLDihydrofolate reductase1.5.1.30.447
4kioG5KTyrosine-protein kinase ITK/TSK2.7.10.20.447
4rupH97Vitamin D3 receptor A/0.447
4xgxADPFAD:protein FMN transferase/0.447
5a3cNADSIR2 family protein/0.447
5fa8SAMRibosomal protein L11 methyltransferase, putative/0.447
5dhhDGWNociceptin receptor/0.447
1db1VDXVitamin D3 receptor/0.446
1dhrNADDihydropteridine reductase1.5.1.340.446
1drbMTXDihydrofolate reductase1.5.1.30.446
1honGNHAdenylosuccinate synthetase/0.446
1jehFADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.446
1lf3EH5Plasmepsin-23.4.23.390.446
1o8cNDPProbable acrylyl-CoA reductase AcuI1.3.1.840.446
1oi9N20Cyclin-dependent kinase 22.7.11.220.446
1pjkANPCasein kinase II subunit alpha2.7.11.10.446
1qrpHH0Pepsin A-43.4.23.10.446
1tezFADDeoxyribodipyrimidine photo-lyase4.1.99.30.446
1xp6AIUEstrogen receptor/0.446
2dbqNAPGlyoxylate reductase1.1.1.260.446
2fy5SOPCholine O-acetyltransferase2.3.1.60.446
2gmhFADElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial1.5.5.10.446
2h3wCOACarnitine O-acetyltransferase2.3.1.70.446
2i0y5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.446
2jd0NDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.446
2q61SF1Peroxisome proliferator-activated receptor gamma/0.446
2vbdV10Isopenicillin N synthase1.21.3.10.446
3cukFADD-amino-acid oxidase1.4.3.30.446
3grrSAHProbable ribosomal RNA small subunit methyltransferase A/0.446
3hz5Z64Heat shock protein HSP 90-alpha/0.446
3iok1P6Tyrosine-protein kinase JAK2/0.446
3pgqGY3Acetyl-CoA carboxylase/0.446
3rnnRNNGlutamate receptor 2/0.446
3tz3B36Acetyl-CoA carboxylase/0.446
3w0yDS4Vitamin D3 receptor/0.446
4a9mP9MBromodomain-containing protein 2/0.446
4ead0NPThymidine phosphorylase2.4.2.40.446
4ejmNAPPutative zinc-binding dehydrogenase/0.446
4fdnFADDecaprenylphosphoryl-beta-D-ribose oxidase/0.446
4fkr45KCyclin-dependent kinase 22.7.11.220.446
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.446
4mwzSAMPhosphoethanolamine N-methyltransferase, putative/0.446
4q73FADBifunctional protein PutA/0.446
4qnuGEKtRNA U34 carboxymethyltransferase/0.446
4xyeNADFormate dehydrogenase/0.446
4y93746Tyrosine-protein kinase/0.446
4yuqKS1Calmodulin-like domain protein kinase/0.446
5a28MYAGlycylpeptide N-tetradecanoyltransferase/0.446
5f8eSAHPossible transcriptional regulatory protein/0.446
1djnADPTrimethylamine dehydrogenase1.5.8.20.445
1e7qNAPGDP-L-fucose synthase/0.445
1g38NEAModification methylase TaqI2.1.1.720.445
1g67TZPThiamine-phosphate synthase/0.445
1gthFADDihydropyrimidine dehydrogenase [NADP(+)]1.3.1.20.445
1q8yADPSerine/threonine-protein kinase SKY12.7.11.10.445
1u4dDBQActivated CDC42 kinase 1/0.445
1vijBAYGag-Pol polyprotein/0.445
1xhaR68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
2c54NADGDP-mannose 3,5-epimerase5.1.3.180.445
2gu8796cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
2hydADPPutative multidrug export ATP-binding/permease protein SAV18663.6.30.445
2iko7IGRenin3.4.23.150.445
2v9jATP5'-AMP-activated protein kinase subunit gamma-1/0.445
2wepADPATP-dependent molecular chaperone HSP82/0.445
3d7zGK5Mitogen-activated protein kinase 14/0.445
3e8cG96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
3g49NAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.445
3gbuATPUncharacterized sugar kinase PH14592.7.10.445
3ii43IIDihydrolipoyl dehydrogenase1.8.1.40.445
3lzu017Gag-Pol polyprotein3.4.23.160.445
4fcwADPChaperone protein ClpB/0.445
4hy6FJ1Heat shock protein HSP 90-alpha/0.445
4i02CMPcAMP-activated global transcriptional regulator CRP/0.445
4kip1R9Mitogen-activated protein kinase 14/0.445
4ktoFADPutative isovaleryl-CoA dehydrogenase protein/0.445
4lj6ACPChaperone protein ClpB/0.445
4mv8ACPBiotin carboxylase6.3.4.140.445
4nd3NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.445
4qppSAHProtein arginine N-methyltransferase 6/0.445
4s26SAHPhosphomethylpyrimidine synthase, chloroplastic4.1.99.170.445
4xumIMNPeroxisome proliferator-activated receptor gamma/0.445
5a3bAPRSIR2 family protein/0.445
5kl9COAAcyl-CoA thioester hydrolase YbgC3.1.20.445
1c6zROCProtease/0.444
1dbvNADGlyceraldehyde-3-phosphate dehydrogenase/0.444
1g4tFTPThiamine-phosphate synthase/0.444
1lsjNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.444
1m2hAPRNAD-dependent protein deacylase 1/0.444
1n2sNAIdTDP-4-dehydrorhamnose reductase1.1.1.1330.444
2cx8SAHRibosomal RNA small subunit methyltransferase E/0.444
2gcgNDPGlyoxylate reductase/hydroxypyruvate reductase1.1.1.790.444
2ou2ACOHistone acetyltransferase KAT5/0.444
2q4wFADCytokinin dehydrogenase 71.5.99.120.444
2qn7HBZGlycogen phosphorylase, muscle form2.4.1.10.444
2uw5GVNcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
2zgzGNPPlasmid segregation protein ParM/0.444
3a1l2CCCytochrome P450/0.444
3be9P04Casein kinase II subunit alpha2.7.11.10.444
3fnlSHALactoperoxidase/0.444
3gc9B45Mitogen-activated protein kinase 112.7.11.240.444
3hwrNDP2-dehydropantoate 2-reductase/0.444
3inwJZBHeat shock protein HSP 90-alpha/0.444
3jskAHZThiamine thiazole synthase/0.444
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.444
3nhkVAPRibosyldihydronicotinamide dehydrogenase [quinone]/0.444
3q87SAMN6 ADENINE SPECIFIC DNA METHYLASE (METHYLTRANSFERASE SUPERFAMILY)/0.444
3tljSAHUncharacterized protein/0.444
4a4vYFDPeroxisome proliferator-activated receptor gamma/0.444
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.444
4j2wFADKynurenine 3-monooxygenase/0.444
4l9kEHFSerum albumin/0.444
4lj7MNTChaperone protein ClpB/0.444
4qi4FADCellobiose dehydrogenase/0.444
4v12POGMaoC like domain protein/0.444
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.444
1eupASD6-deoxyerythronolide B hydroxylase/0.443
1f4gTP4Thymidylate synthase/0.443
1m17AQ4Epidermal growth factor receptor2.7.10.10.443
1m2rMNYCasein kinase II subunit alpha2.7.11.10.443
1pmn984Mitogen-activated protein kinase 102.7.11.240.443
1thnADPAnti-sigma F factor/0.443
2cibCM6Lanosterol 14-alpha demethylase1.14.13.700.443
2cig1DGDihydrofolate reductase1.5.1.30.443
2daaDCSD-alanine aminotransferase2.6.1.210.443
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.443
2ebaFADPutative glutaryl-CoA dehydrogenase/0.443
2fxv5GPXanthine phosphoribosyltransferase2.4.2.220.443
2i4zDRHPeroxisome proliferator-activated receptor gamma/0.443
2ien017Gag-Pol polyprotein3.4.23.160.443
2nv6ZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
2q3kMUWGag-Pol polyprotein/0.443
2r3wG3GGag-Pol polyprotein3.4.23.160.443
3ac3KSHTyrosine-protein kinase Lck2.7.10.20.443
3etdNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.443
3hub469Mitogen-activated protein kinase 14/0.443
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.443
3inxJZCHeat shock protein HSP 90-alpha/0.443
3mzhCMPCRP-like cAMP-activated global transcriptional regulator/0.443
3oom507Activin receptor type-12.7.11.300.443
3poz03PEpidermal growth factor receptor2.7.10.10.443
3q43D66M1 family aminopeptidase3.4.110.443
3qqlX03Cyclin-dependent kinase 22.7.11.220.443
3qwbNDPProbable quinone oxidoreductase1.6.5.50.443
3rpv26ZCyclin-dependent kinase 22.7.11.220.443
3sz0FADSulfide-quinone reductase/0.443
3t2kFADSulfide-quinone reductase/0.443
3t7tSAHUncharacterized protein/0.443
4bcoT6QCyclin-dependent kinase 22.7.11.220.443
4c05SAHProtein arginine N-methyltransferase 6/0.443
4f7iNAD3-isopropylmalate dehydrogenase1.1.1.850.443
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.443
4hgl0YOCasein kinase I isoform gamma-32.7.11.10.443
4i3wNADAldehyde dehydrogenase (NAD+)/0.443
4kfn1QRNicotinamide phosphoribosyltransferase2.4.2.120.443
4m4922YL-lactate dehydrogenase A chain1.1.1.270.443
4qq3XMPInosine-5'-monophosphate dehydrogenase/0.443
4u0mGTPCyclic GMP-AMP synthase/0.443
1ebk0Q4Gag-Pol polyprotein3.4.23.160.442
1heuNADAlcohol dehydrogenase E chain1.1.1.10.442
1j39UPGDNA beta-glucosyltransferase/0.442
1jolFFODihydrofolate reductase1.5.1.30.442
1kvkATPMevalonate kinase2.7.1.360.442
1p0hACOMycothiol acetyltransferase2.3.1.1890.442
2aquDR7Gag-Pol polyprotein3.4.23.160.442
2c29NAPDihydroflavonol 4-reductase/0.442
2ca0PXICytochrome P450 monooxygenase PikC/0.442
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.442
2uw0GVKcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.442
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.442
3ezvEZVCyclin-dependent kinase 22.7.11.220.442
3mws017Pol protein/0.442
3nduROCGag-Pol polyprotein3.4.23.160.442
3qv1NADGlyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic1.2.1.130.442
3t8wDGZM17 leucyl aminopeptidase/0.442
3tk3CPZCytochrome P450 2B41.14.14.10.442
3w0rANPHygromycin-B 4-O-kinase2.7.1.1630.442
3wdlATP4-phosphopantoate--beta-alanine ligase6.3.2.360.442
4fd2ADPChaperone protein ClpB/0.442
4fv8E63Mitogen-activated protein kinase 12.7.11.240.442
5il2SAHN6-adenosine-methyltransferase 70 kDa subunit/0.442
1aiqCB3Thymidylate synthase/0.441
1cydNDPCarbonyl reductase [NADPH] 21.1.1.1840.441
1ivhCOSIsovaleryl-CoA dehydrogenase, mitochondrial1.3.8.40.441
1k6cMK1Gag-Pol polyprotein3.4.23.160.441
1lwiNAP3-alpha-hydroxysteroid dehydrogenase1.1.1.500.441
1mawATPTryptophan--tRNA ligase6.1.1.20.441
1poxFADPyruvate oxidase1.2.3.30.441
1ppjANYCytochrome b/0.441
1v59FADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.441
1x14NADNAD(P) transhydrogenase subunit alpha1.6.1.20.441
1xh6R94cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
2b9wFADPutative aminooxidase/0.441
2bb9AKCGag-Pol polyprotein3.4.23.160.441
2bbbHH1Gag-Pol polyprotein3.4.23.160.441
2c27ACOMycothiol acetyltransferase2.3.1.1890.441
2c59NADGDP-mannose 3,5-epimerase5.1.3.180.441
2duv371Cyclin-dependent kinase 22.7.11.220.441
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.441
2iviACWIsopenicillin N synthase1.21.3.10.441
2p20PRXAcetyl-coenzyme A synthetase/0.441
2qtcTDKPyruvate dehydrogenase E1 component1.2.4.10.441
2xaaNADSecondary alcohol dehydrogenase/0.441
3adaNADSubunit alpha of sarocosine oxidase/0.441
3b20NADGlyceraldehyde-3-phosphate dehydrogenase/0.441
3g7jGTXGlutathione transferase GST1-4/0.441
3gobHXXDdmC/0.441
3od0PCGcGMP-dependent protein kinase 12.7.11.120.441
3ruqADPChaperonin/0.441
3u4cNDPNADPH-dependent reductase BacG/0.441
4enhFVXCholesterol 24-hydroxylase/0.441
4f9c0SXCell division cycle 7-related protein kinase2.7.11.10.441
4ge40KEKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.441
4ge70K5Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.441
4gyy12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.441
4hjoAQ4Epidermal growth factor receptor2.7.10.10.441
4hmz18TdTDP-4-dehydro-6-deoxyglucose 3-epimerase5.1.3.270.441
4jx1CAMCamphor 5-monooxygenase1.14.15.10.441
4nu5NADPhosphonate dehydrogenase1.20.1.10.441
4o2bLOCTubulin beta-2B chain/0.441
4uwmFMN3,6-diketocamphane 1,6 monooxygenase1.14.130.441
4xguADPPutative pachytene checkpoint protein 2/0.441
5dr9SKEAurora kinase A2.7.11.10.441
1c6yMK1Protease/0.440
1dgfNDPCatalase1.11.1.60.440
1dgmADNAdenosine kinase2.7.1.200.440
1hf3NADAlcohol dehydrogenase E chain1.1.1.10.440
1ivq0PXGag-Pol polyprotein/0.440
1mokFAD2-oxopropyl-CoM reductase, carboxylating1.8.1.50.440
1psdNADD-3-phosphoglycerate dehydrogenase1.1.1.950.440
1qiqACCIsopenicillin N synthase1.21.3.10.440
2b7aIZATyrosine-protein kinase JAK2/0.440
2bdjHETProto-oncogene tyrosine-protein kinase Src2.7.10.20.440
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.440
2g9uG27Glycogen phosphorylase, muscle form2.4.1.10.440
2gjlFMNNitronate monooxygenase1.13.12.160.440
2hk9NAPShikimate dehydrogenase (NADP(+))/0.440
2hog710Serine/threonine-protein kinase Chk12.7.11.10.440
2izt23DCasein kinase I isoform gamma-32.7.11.10.440
2jn3JN3Fatty acid-binding protein, liver/0.440
2npxNADNADH peroxidase1.11.1.10.440
2pvlP55Casein kinase II subunit alpha2.7.11.10.440
2qa1FADPgaE/0.440
2r9kSGIBeta-galactoside-specific lectin 1/0.440
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.440
2xyeCXGGag-Pol polyprotein/0.440
2y0mACOHistone acetyltransferase KAT8/0.440
2y37A54Nitric oxide synthase, inducible1.14.13.390.440
3cyw017Gag-Pol polyprotein3.4.23.160.440
3ggpNADPrephenate dehydrogenase/0.440
3ha5SFGHydroxymycolate synthase MmaA42.1.10.440
3i8p8403-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.440
3l0lHC3Nuclear receptor ROR-gamma/0.440
3to6LYS_CMCHistone acetyltransferase ESA1/0.440
3w0nANPHygromycin-B 4-O-kinase2.7.1.1630.440
3zuxTCHTransporter/0.440
4aqc88ATyrosine-protein kinase JAK2/0.440
4az3S35Lysosomal protective protein3.4.16.50.440
4bgiI4IEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
4c3yANB3-ketosteroid dehydrogenase/0.440
4ekeD1IGlycogen phosphorylase, muscle form2.4.1.10.440
4ge90L0Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.440
4ktc1X3Genome polyprotein3.4.21.980.440
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.440
4wjiNAPPutative cyclohexadienyl dehydrogenase and ADH prephenate dehydrogenase/0.440
4xq9NADHomospermidine synthase2.5.1.440.440
4ylfFADDihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit homolog/0.440
4z24FADPutative GMC-type oxidoreductase R13510.440
5cdtPFBAlcohol dehydrogenase E chain1.1.1.10.440
5d4uSAMUncharacterized protein MJ0489/0.440