sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3um8 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3um8 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 1.000 | |
| 2bla | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.637 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.619 | |
| 2blb | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.608 | |
| 3um5 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.606 | |
| 4ixe | IXE | Dihydrofolate reductase | 1.5.1.3 | 0.605 | |
| 1klk | PMD | Dihydrofolate reductase | 1.5.1.3 | 0.596 | |
| 3qg2 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.593 | |
| 3qly | 55V | Uncharacterized protein | / | 0.591 | |
| 3iro | 2CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.590 | |
| 1m78 | CLZ | Dihydrofolate reductase | 1.5.1.3 | 0.581 | |
| 3dga | RJ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.581 | |
| 1aoe | GW3 | Dihydrofolate reductase | 1.5.1.3 | 0.578 | |
| 4m6l | 21V | Dihydrofolate reductase | 1.5.1.3 | 0.577 | |
| 3irn | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.576 | |
| 3qlr | QLR | Dihydrofolate reductase | 1.5.1.3 | 0.576 | |
| 3um6 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.575 | |
| 3qfx | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.572 | |
| 1dg5 | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.571 | |
| 4h96 | 14Q | Dihydrofolate reductase | 1.5.1.3 | 0.569 | |
| 1j3j | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.567 | |
| 1boz | PRD | Dihydrofolate reductase | 1.5.1.3 | 0.566 | |
| 1e26 | GPB | Dihydrofolate reductase | 1.5.1.3 | 0.564 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.564 | |
| 3inv | C50 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.564 | |
| 3qls | 55V | Dihydrofolate reductase | 1.5.1.3 | 0.564 | |
| 3dg8 | RJ6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.560 | |
| 3qgt | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.559 | |
| 4dph | P65 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.559 | |
| 1cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.557 | |
| 1qzf | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.557 | |
| 4keb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.557 | |
| 1hfp | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.556 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.555 | |
| 3jsu | KA5 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.552 | |
| 1j3k | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.551 | |
| 2blc | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.550 | |
| 2zza | FOL | Dihydrofolate reductase | / | 0.547 | |
| 2cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.546 | |
| 3kjs | DQ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.546 | |
| 1vj3 | TAB | Dihydrofolate reductase | 1.5.1.3 | 0.545 | |
| 1ia1 | TQ3 | Dihydrofolate reductase | 1.5.1.3 | 0.544 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.544 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.541 | |
| 2fzh | DH1 | Dihydrofolate reductase | 1.5.1.3 | 0.539 | |
| 2bl9 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.536 | |
| 3s3v | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.535 | |
| 4dp3 | MMV | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.535 | |
| 3qlx | QLR | Uncharacterized protein | / | 0.534 | |
| 7dfr | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.534 | |
| 1ia2 | TQ4 | Dihydrofolate reductase | 1.5.1.3 | 0.532 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.532 | |
| 1m7a | MQU | Dihydrofolate reductase | 1.5.1.3 | 0.531 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.530 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.530 | |
| 3eek | 53S | Uncharacterized protein | / | 0.529 | |
| 4x5f | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.529 | |
| 1bzf | TMQ | Dihydrofolate reductase | 1.5.1.3 | 0.527 | |
| 1j3i | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.525 | |
| 3cse | N22 | Uncharacterized protein | / | 0.524 | |
| 3l3r | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.523 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.522 | |
| 3nxo | D2B | Dihydrofolate reductase | 1.5.1.3 | 0.522 | |
| 4g8z | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.522 | |
| 4nx6 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.522 | |
| 4kbn | 25U | Dihydrofolate reductase | 1.5.1.3 | 0.521 | |
| 4m2x | TMQ | Dihydrofolate reductase | 1.5.1.3 | 0.521 | |
| 1ohj | COP | Dihydrofolate reductase | 1.5.1.3 | 0.520 | |
| 2w3a | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.520 | |
| 2w3m | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.519 | |
| 5ccc | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.518 | |
| 3qlz | QLZ | Uncharacterized protein | / | 0.517 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.517 | |
| 1daj | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.516 | |
| 3rg9 | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.516 | |
| 1ddr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.514 | |
| 4kd7 | 9DR | Dihydrofolate reductase | 1.5.1.3 | 0.514 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.513 | |
| 3clb | TMQ | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.513 | |
| 3ghw | GHW | Dihydrofolate reductase | 1.5.1.3 | 0.512 | |
| 3nxr | D2D | Dihydrofolate reductase | 1.5.1.3 | 0.512 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.511 | |
| 3eej | 53R | Uncharacterized protein | / | 0.511 | |
| 3nxt | D2E | Dihydrofolate reductase | 1.5.1.3 | 0.511 | |
| 3nxv | D2F | Dihydrofolate reductase | 1.5.1.3 | 0.511 | |
| 3eem | 53V | Uncharacterized protein | / | 0.510 | |
| 1dg7 | WRB | Dihydrofolate reductase | 1.5.1.3 | 0.509 | |
| 3cd2 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.509 | |
| 4kak | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.509 | |
| 3ql3 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.508 | |
| 3tqb | FOL | Dihydrofolate reductase | / | 0.508 | |
| 3ntz | 3TZ | Dihydrofolate reductase | 1.5.1.3 | 0.507 | |
| 1re7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.506 | |
| 4p66 | MTX | Dihydrofolate reductase | / | 0.505 | |
| 1dyr | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.504 | |
| 3nxy | D2H | Dihydrofolate reductase | 1.5.1.3 | 0.504 | |
| 3lfc | Z86 | Mitogen-activated protein kinase 14 | / | 0.503 | |
| 1r00 | SAH | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.502 | |
| 4ixf | IXF | Dihydrofolate reductase | 1.5.1.3 | 0.502 | |
| 2w3w | VG9 | Dihydrofolate reductase | / | 0.501 | |
| 4ixg | IXG | Dihydrofolate reductase | 1.5.1.3 | 0.501 | |
| 1rx3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.500 | |
| 1s3y | TQT | Dihydrofolate reductase | 1.5.1.3 | 0.500 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.499 | |
| 1dds | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.498 | |
| 1rc4 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.498 | |
| 1rx6 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.498 | |
| 3dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.497 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.497 | |
| 4p68 | MTX | Dihydrofolate reductase | / | 0.497 | |
| 4x5g | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.497 | |
| 1ly3 | COG | Dihydrofolate reductase | 1.5.1.3 | 0.496 | |
| 3och | 2MX | Dihydrofolate reductase | 1.5.1.3 | 0.496 | |
| 4ej1 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.496 | |
| 3gi2 | GHW | Dihydrofolate reductase | 1.5.1.3 | 0.495 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.495 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.494 | |
| 1hfr | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.494 | |
| 1rf7 | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.494 | |
| 4kfj | 1R0 | Dihydrofolate reductase | 1.5.1.3 | 0.494 | |
| 1kms | LIH | Dihydrofolate reductase | 1.5.1.3 | 0.492 | |
| 1rb3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.492 | |
| 3tq9 | MTX | Dihydrofolate reductase | / | 0.492 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.492 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.491 | |
| 4eil | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.491 | |
| 4h98 | 14Q | Uncharacterized protein | / | 0.490 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.489 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.489 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.489 | |
| 2w3v | TOP | Dihydrofolate reductase | / | 0.489 | |
| 3gyf | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.489 | |
| 3r33 | 6ME | Dihydrofolate reductase | 1.5.1.3 | 0.489 | |
| 3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.489 | |
| 3w6h | AZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.489 | |
| 4lb2 | DM5 | Serum albumin | / | 0.489 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.488 | |
| 1dre | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.487 | |
| 1kmv | LII | Dihydrofolate reductase | 1.5.1.3 | 0.487 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.487 | |
| 2p15 | EZT | Estrogen receptor | / | 0.487 | |
| 4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.487 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.487 | |
| 1ao8 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.486 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.486 | |
| 3l8s | BFF | Mitogen-activated protein kinase 14 | / | 0.486 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.486 | |
| 3tq8 | TOP | Dihydrofolate reductase | / | 0.486 | |
| 4x5j | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.486 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.485 | |
| 1s3w | TQT | Dihydrofolate reductase | 1.5.1.3 | 0.485 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.485 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.484 | |
| 3iqz | H4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.483 | |
| 4kjj | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.483 | |
| 3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.482 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.482 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.482 | |
| 1s7g | NAD | NAD-dependent protein deacylase 2 | / | 0.481 | |
| 3gcq | 1BU | Mitogen-activated protein kinase 14 | / | 0.480 | |
| 3k47 | D09 | Dihydrofolate reductase | 1.5.1.3 | 0.480 | |
| 3srs | M23 | Dihydrofolate reductase | 1.5.1.3 | 0.480 | |
| 3up0 | D7S | aceDAF-12 | / | 0.480 | |
| 4e0u | 0MV | Cyclic dipeptide N-prenyltransferase | / | 0.480 | |
| 1rx7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.479 | |
| 3eel | 53T | Uncharacterized protein | / | 0.479 | |
| 3sa1 | 6DR | Dihydrofolate reductase | / | 0.479 | |
| 3ue4 | DB8 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.479 | |
| 2fzj | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.478 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.478 | |
| 4nx7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.478 | |
| 1df7 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.477 | |
| 1jom | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.477 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.477 | |
| 4dvq | 1CA | Cytochrome P450 11B2, mitochondrial | 1.14.15.4 | 0.476 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.475 | |
| 2ovv | PFH | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.475 | |
| 3dau | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.475 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.475 | |
| 3jwc | EKB | Dihydrofolate reductase | / | 0.475 | |
| 3td8 | D2R | Dihydrofolate reductase | 1.5.1.3 | 0.475 | |
| 3vuf | ADP | Granule-bound starch synthase 1, chloroplastic/amyloplastic | 2.4.1.242 | 0.475 | |
| 4j7x | SAS | Sepiapterin reductase | 1.1.1.153 | 0.475 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.474 | |
| 2g44 | T3O | Estrogen receptor | / | 0.474 | |
| 4i6h | 1C8 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.474 | |
| 4x5h | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 1rh3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.473 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.473 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.472 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.472 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.472 | |
| 4m7v | RAR | Dihydrofolate reductase | / | 0.472 | |
| 2y46 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.471 | |
| 3sgy | 06W | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 1rd7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 3sqy | Q11 | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 4m6k | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 4xoq | F42 | Coenzyme F420:L-glutamate ligase | / | 0.469 | |
| 1ra2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.468 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.468 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.468 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.468 | |
| 4j24 | EST | Estrogen receptor beta | / | 0.468 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.468 | |
| 1rx2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 1xpc | AIT | Estrogen receptor | / | 0.467 | |
| 2oax | SNL | Mineralocorticoid receptor | / | 0.467 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.467 | |
| 3ml8 | ML8 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.467 | |
| 4fev | PP1 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.467 | |
| 5d7q | 4I5 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.467 | |
| 1dgf | NDP | Catalase | 1.11.1.6 | 0.465 | |
| 1og5 | SWF | Cytochrome P450 2C9 | / | 0.465 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.465 | |
| 3d80 | Q22 | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.465 | |
| 4gki | 0JN | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.465 | |
| 4gyz | D5M | Tyrosyl-DNA phosphodiesterase 2 | 3.1.4 | 0.465 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.465 | |
| 1dr4 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 2c94 | TSF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.464 | |
| 3oji | PYV | Abscisic acid receptor PYL3 | / | 0.464 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.464 | |
| 2o8h | 227 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.463 | |
| 3ikt | NAD | Redox-sensing transcriptional repressor Rex | / | 0.463 | |
| 3o56 | ZG1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.463 | |
| 3pre | 3RE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.463 | |
| 3zbn | COA | 3-ketoacyl-CoA thiolase-like protein | / | 0.463 | |
| 4kne | 1CY | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 2obx | INI | 6,7-dimethyl-8-ribityllumazine synthase 2 | 2.5.1.78 | 0.462 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.462 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.462 | |
| 4ddr | MMV | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 1dra | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1o5r | FR9 | Adenosine deaminase | 3.5.4.4 | 0.461 | |
| 1yc2 | NAD | NAD-dependent protein deacylase 2 | / | 0.461 | |
| 4iv2 | 1GR | Estrogen receptor | / | 0.461 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.461 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 1dli | UDX | UDP-glucose 6-dehydrogenase | / | 0.460 | |
| 1nhz | 486 | Glucocorticoid receptor | / | 0.460 | |
| 2azz | TCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.460 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 2p1u | 4TN | Retinoic acid receptor RXR-alpha | / | 0.460 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.460 | |
| 3sr5 | Q12 | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 3zia | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.460 | |
| 4czt | CPS | CBL-interacting serine/threonine-protein kinase 23 | 2.7.11.1 | 0.460 | |
| 4few | PP2 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.460 | |
| 4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.460 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.459 | |
| 1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.459 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.459 | |
| 4gkh | 0J9 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.459 | |
| 2drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.458 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.458 | |
| 3oad | LPO | Renin | 3.4.23.15 | 0.458 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.458 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.458 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 2c9d | PHR | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.457 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.457 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.457 | |
| 3frf | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.457 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.456 | |
| 1jtu | LYB | Thymidylate synthase | / | 0.456 | |
| 2b37 | 8PS | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.456 | |
| 2chw | 039 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.456 | |
| 2jed | LG8 | Protein kinase C theta type | 2.7.11.13 | 0.456 | |
| 2q7g | CCL | Pyrrolysine--tRNA ligase | / | 0.456 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.456 | |
| 4fcd | 0T6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.456 | |
| 4feu | 537 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.456 | |
| 4fhb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 4hw3 | 19G | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.456 | |
| 4i13 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1fm6 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.455 | |
| 1k27 | MTM | S-methyl-5'-thioadenosine phosphorylase | / | 0.455 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.455 | |
| 2ph5 | NAD | Homospermidine synthase | / | 0.455 | |
| 3cv9 | VDX | Vitamin D3 dihydroxylase | / | 0.455 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.455 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.455 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.455 | |
| 4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1dgh | NDP | Catalase | 1.11.1.6 | 0.454 | |
| 1ly4 | COQ | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1u71 | MXA | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.454 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 3qyo | Q24 | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 4py6 | R78 | Bromodomain protein, putative | / | 0.454 | |
| 1kl2 | FON | Serine hydroxymethyltransferase | / | 0.453 | |
| 1n8w | COA | Malate synthase G | / | 0.453 | |
| 1s3v | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 2wd8 | VGF | Pteridine reductase | / | 0.453 | |
| 2ykb | YKB | Heat shock protein HSP 90-alpha | / | 0.453 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.453 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.453 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.453 | |
| 3pz2 | 3PZ | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.453 | |
| 3qj5 | 022 | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.453 | |
| 3zsh | 469 | Mitogen-activated protein kinase 14 | / | 0.453 | |
| 4alh | A9P | Bromodomain-containing protein 2 | / | 0.453 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
| 4g09 | 0VD | Histidinol dehydrogenase | / | 0.453 | |
| 4hni | 16W | Casein kinase I isoform epsilon | 2.7.11.1 | 0.453 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.453 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.453 | |
| 4mv1 | ADP | Biotin carboxylase | 6.3.4.14 | 0.453 | |
| 5cc9 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1nbm | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.452 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 1qxl | FR8 | Adenosine deaminase | 3.5.4.4 | 0.452 | |
| 1rf9 | DBR | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 1t13 | INI | 6,7-dimethyl-8-ribityllumazine synthase 2 | / | 0.452 | |
| 1tdr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1uym | PU3 | Heat shock protein HSP 90-beta | / | 0.452 | |
| 1yry | MSG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.452 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.452 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.452 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.452 | |
| 3k45 | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1l2i | ETC | Estrogen receptor | / | 0.451 | |
| 1rx5 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.451 | |
| 2g5o | DRQ | Estrogen receptor | / | 0.451 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.451 | |
| 3csd | EMO | Putative ketoacyl reductase | 1.3.1 | 0.451 | |
| 3ezp | B3N | Histone deacetylase 8 | 3.5.1.98 | 0.451 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.451 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.451 | |
| 4fj2 | QSO | 17beta-hydroxysteroid dehydrogenase | / | 0.451 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.450 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 1ove | 358 | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 1pd8 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1ra8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1rb2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1sd1 | FMC | S-methyl-5'-thioadenosine phosphorylase | / | 0.450 | |
| 1v3q | 2DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.450 | |
| 2jc6 | QPP | Calcium/calmodulin-dependent protein kinase type 1D | 2.7.11.17 | 0.450 | |
| 2pnu | ENM | Androgen receptor | / | 0.450 | |
| 2zce | PYL | Pyrrolysine--tRNA ligase | / | 0.450 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.450 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.450 | |
| 3lak | KR1 | Gag-Pol polyprotein | 2.7.7.49 | 0.450 | |
| 1dhj | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1q5d | EPB | Epothilone C/D epoxidase | 1.14 | 0.449 | |
| 1u72 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 3hcr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.449 | |
| 4bgi | I4I | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 4bwa | N0B | Pyrrolysine--tRNA ligase | / | 0.449 | |
| 4ele | 31I | Dihydrofolate reductase | / | 0.449 | |
| 5dc5 | B3N | Histone deacetylase 8 | 3.5.1.98 | 0.449 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.449 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.448 | |
| 1dyi | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1fml | RTL | Retinol dehydratase | / | 0.448 | |
| 1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.448 | |
| 1uy6 | PU3 | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 2nr4 | FMN | Conserved protein | / | 0.448 | |
| 2qgt | EED | Estrogen receptor | / | 0.448 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 3iqf | E4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.448 | |
| 3s7a | 684 | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 3sh2 | 5DR | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 4fex | 0TO | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.448 | |
| 4iw8 | KN3 | Estrogen receptor | / | 0.448 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.448 | |
| 1al8 | DHP | Peroxisomal (S)-2-hydroxy-acid oxidase | 1.1.3.15 | 0.447 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.447 | |
| 1e90 | MYC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
| 1zky | 689 | Estrogen receptor | / | 0.447 | |
| 2ocf | EST | Estrogen receptor | / | 0.447 | |
| 2on6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.447 | |
| 2ovh | AS0 | Progesterone receptor | / | 0.447 | |
| 2ovm | AS0 | Progesterone receptor | / | 0.447 | |
| 3bqd | DAY | Glucocorticoid receptor | / | 0.447 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.447 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.447 | |
| 3p99 | LNP | Lanosterol 14-alpha-demethylase | / | 0.447 | |
| 3rue | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.447 | |
| 3zrb | OR8 | Progesterone receptor | / | 0.447 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.447 | |
| 4j4v | SVR | Nucleocapsid protein | / | 0.447 | |
| 4k39 | SAM | Anaerobic sulfatase-maturating enzyme | 1.8.98 | 0.447 | |
| 4k9y | K9Y | Focal adhesion kinase 1 | 2.7.10.2 | 0.447 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 4lht | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.447 | |
| 4lsj | LSJ | Glucocorticoid receptor | / | 0.447 | |
| 4mv4 | ACP | Biotin carboxylase | 6.3.4.14 | 0.447 | |
| 4ri1 | ACO | UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase | 2.3.1.202 | 0.447 | |
| 4uda | DEX | Mineralocorticoid receptor | / | 0.447 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 1uy7 | PU4 | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 2a3i | C0R | Mineralocorticoid receptor | / | 0.446 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.446 | |
| 2y98 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.446 | |
| 2zjw | REF | Casein kinase II subunit alpha | 2.7.11.1 | 0.446 | |
| 3fr2 | 8CA | Fatty acid-binding protein, adipocyte | / | 0.446 | |
| 3gxo | MQA | Mitomycin biosynthesis 6-O-methyltransferase | / | 0.446 | |
| 3h4v | DVP | Pteridine reductase 1 | 1.5.1.33 | 0.446 | |
| 3jwm | 5WB | Dihydrofolate reductase | / | 0.446 | |
| 3o73 | O73 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.446 | |
| 3sls | 77D | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.446 | |
| 3sru | Q26 | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 4lrr | CF9 | Thymidylate synthase | / | 0.446 | |
| 4m52 | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.446 | |
| 1rg7 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1uhl | MEI | Retinoic acid receptor RXR-beta | / | 0.445 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 1xuo | LA1 | Integrin alpha-L | / | 0.445 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.445 | |
| 2b00 | GCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.445 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.445 | |
| 3a26 | MTA | tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase | / | 0.445 | |
| 3ut5 | LOC | Tubulin beta chain | / | 0.445 | |
| 3vjc | ZGA | Squalene synthase | 2.5.1.21 | 0.445 | |
| 4at3 | LTI | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.445 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.445 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.445 | |
| 4geb | 0LD | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.445 | |
| 4gev | CB3 | Thymidylate synthase | / | 0.445 | |
| 4l4f | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 1d2s | DHT | Sex hormone-binding globulin | / | 0.444 | |
| 1dlj | UGA | UDP-glucose 6-dehydrogenase | / | 0.444 | |
| 1l2j | ETC | Estrogen receptor beta | / | 0.444 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.444 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.444 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 2e99 | B08 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.444 | |
| 2ejz | SAH | Diphthine synthase | / | 0.444 | |
| 2fm0 | M98 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.444 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.444 | |
| 2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 3fc6 | REA | Retinoic acid receptor RXR-alpha | / | 0.444 | |
| 3zra | ORB | Progesterone receptor | / | 0.444 | |
| 4d7e | FAD | Putative lysine-N-oxygenase | / | 0.444 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.444 | |
| 4xe6 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 4xwt | U5P | Ribonuclease J | / | 0.444 | |
| 1a4i | NDP | C-1-tetrahydrofolate synthase, cytoplasmic | 1.5.1.5 | 0.443 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.443 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.443 | |
| 2cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 2fai | 459 | Estrogen receptor | / | 0.443 | |
| 2ykj | YKJ | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 3huc | G97 | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 3sqx | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.443 | |
| 3v94 | WYQ | Phosphodiesterase | / | 0.443 | |
| 3wsb | RWZ | Farnesyltransferase, putative | / | 0.443 | |
| 4bmp | FMN | Protein NrdI | / | 0.443 | |
| 4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
| 4g1n | NZT | Pyruvate kinase PKM | 2.7.1.40 | 0.443 | |
| 1e1n | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.442 | |
| 1jol | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1l8q | ADP | Chromosomal replication initiator protein DnaA | / | 0.442 | |
| 1pq6 | 965 | Oxysterols receptor LXR-beta | / | 0.442 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1wc0 | APC | Adenylate cyclase | / | 0.442 | |
| 2fs4 | PZ1 | Renin | 3.4.23.15 | 0.442 | |
| 2g28 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.442 | |
| 2h55 | DZ8 | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 2ntv | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.442 | |
| 2ojg | 19A | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.442 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.442 | |
| 3el8 | PD5 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.442 | |
| 3fal | REA | Retinoic acid receptor RXR-alpha | / | 0.442 | |
| 3ghv | GHC | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.442 | |
| 3h18 | PMS | Esterase/lipase | / | 0.442 | |
| 3iw8 | HIZ | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.442 | |
| 4iq7 | 1G9 | Mycocyclosin synthase | 1.14.21.9 | 0.442 | |
| 4qa2 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.442 | |
| 4u7w | NDP | MxaA | / | 0.442 | |
| 4x5i | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 5akk | 1P8 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.442 | |
| 5d1b | TSN | Histone deacetylase 8 | 3.5.1.98 | 0.442 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.441 | |
| 1qkn | RAL | Estrogen receptor beta | / | 0.441 | |
| 1rv1 | IMZ | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.441 | |
| 1vzd | CB3 | Thymidylate synthase | / | 0.441 | |
| 1yqj | 6NP | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 2d0k | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.441 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.441 | |
| 3l03 | 4OH | Estrogen receptor | / | 0.441 | |
| 3nks | ACJ | Protoporphyrinogen oxidase | 1.3.3.4 | 0.441 | |
| 3p6n | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.441 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.441 | |
| 5c8w | PCG | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.441 | |
| 1drf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1e7v | LY2 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.440 | |
| 1ro9 | 8BR | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.440 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.440 | |
| 1thz | 326 | Bifunctional purine biosynthesis protein PURH | 2.1.2.3 | 0.440 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.440 | |
| 1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.440 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.440 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.440 | |
| 3itz | P66 | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 3thr | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.440 | |
| 4iui | 1GQ | Estrogen receptor | / | 0.440 | |
| 4ivy | 1GT | Estrogen receptor | / | 0.440 | |
| 4l4c | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 4qjc | IXE | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 4qmx | H8H | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.440 | |
| 4u0o | MTA | Lipoyl synthase 2 | / | 0.440 | |
| 4y9u | NAP | NADPH--cytochrome P450 reductase | / | 0.440 |