sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3dh9 | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 3dh9 | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 1.387 | |
| 2nvk | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 1.291 | |
| 3dgh | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 1.222 | |
| 3dk8 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.129 | |
| 2x8h | FAD | Thioredoxin glutathione reductase | / | 1.106 | |
| 3dk4 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.095 | |
| 1gsn | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.083 | |
| 3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.081 | |
| 1ges | FAD | Glutathione reductase | 1.8.1.7 | 1.075 | |
| 2gh5 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.073 | |
| 2x8g | FAD | Thioredoxin glutathione reductase | / | 1.071 | |
| 3dk9 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.071 | |
| 1ger | FAD | Glutathione reductase | 1.8.1.7 | 1.065 | |
| 2hqm | FAD | Glutathione reductase | 1.8.1.7 | 1.062 | |
| 1grb | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.055 | |
| 1geu | FAD | Glutathione reductase | 1.8.1.7 | 1.053 | |
| 1zk7 | FAD | Mercuric reductase | 1.16.1.1 | 1.052 | |
| 3djg | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.052 | |
| 1dnc | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.048 | |
| 1bwc | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.044 | |
| 1zx9 | FAD | Mercuric reductase | 1.16.1.1 | 1.044 | |
| 1gre | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.042 | |
| 2v6o | FAD | Thioredoxin glutathione reductase | / | 1.041 | |
| 3ean | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 1.036 | |
| 3qfa | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 1.034 | |
| 1grh | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.029 | |
| 4j57 | FAD | Thioredoxin reductase 2 | 1.8.1.9 | 1.020 | |
| 3dgz | FAD | Thioredoxin reductase 2, mitochondrial | 1.8.1.9 | 1.017 | |
| 3grs | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.015 | |
| 4la1 | FAD | Thioredoxin glutathione reductase | / | 1.010 | |
| 2eq7 | FAD | Dihydrolipoyl dehydrogenase | / | 1.008 | |
| 2r9z | FAD | Glutathione amide reductase | / | 1.008 | |
| 1get | FAD | Glutathione reductase | 1.8.1.7 | 1.005 | |
| 2zzc | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 1.003 | |
| 1grg | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 1.000 | |
| 1gra | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.988 | |
| 1k4q | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.979 | |
| 2wow | FAD | Trypanothione reductase | / | 0.976 | |
| 2rab | FAD | Glutathione amide reductase | / | 0.971 | |
| 3sqp | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.971 | |
| 4kpr | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.963 | |
| 2wba | FAD | Trypanothione reductase | 1.8.1.12 | 0.958 | |
| 2eq6 | FAD | Dihydrolipoyl dehydrogenase | / | 0.952 | |
| 2tpr | FAD | Trypanothione reductase | 1.8.1.12 | 0.950 | |
| 2cfy | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.946 | |
| 2eq8 | FAD | Dihydrolipoyl dehydrogenase | / | 0.938 | |
| 2wp5 | FAD | Trypanothione reductase | / | 0.938 | |
| 3rnm | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.933 | |
| 1v59 | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.928 | |
| 4b1b | FAD | Thioredoxin reductase | 1.8.1.9 | 0.923 | |
| 1fec | FAD | Trypanothione reductase | 1.8.1.12 | 0.919 | |
| 4gr1 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.919 | |
| 4jq9 | FAD | Dihydrolipoyl dehydrogenase | / | 0.914 | |
| 1feb | FAD | Trypanothione reductase | 1.8.1.12 | 0.913 | |
| 2zz0 | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.908 | |
| 1f8w | FAD | NADH peroxidase | 1.11.1.1 | 0.907 | |
| 1gxf | FAD | Trypanothione reductase | 1.8.1.12 | 0.901 | |
| 1zmd | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.899 | |
| 3qfb | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.894 | |
| 2eq9 | FAD | Dihydrolipoyl dehydrogenase | / | 0.885 | |
| 1h6v | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.884 | |
| 2jk6 | FAD | Trypanothione reductase | / | 0.884 | |
| 2f5z | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.883 | |
| 1npx | FAD | NADH peroxidase | 1.11.1.1 | 0.879 | |
| 1nhp | FAD | NADH peroxidase | 1.11.1.1 | 0.873 | |
| 1ebd | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.871 | |
| 2c3c | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.869 | |
| 4fwf | FAD | Lysine-specific histone demethylase 1B | 1 | 0.868 | |
| 4jdr | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.867 | |
| 4nev | FAD | Trypanothione reductase | / | 0.867 | |
| 2npx | FAD | NADH peroxidase | 1.11.1.1 | 0.866 | |
| 1onf | FAD | Glutathione reductase | 1.8.1.7 | 0.863 | |
| 3lad | FAD | Dihydrolipoyl dehydrogenase | / | 0.862 | |
| 1nhr | FAD | NADH peroxidase | 1.11.1.1 | 0.858 | |
| 1bzl | FAD | Trypanothione reductase | 1.8.1.12 | 0.855 | |
| 1nhs | FAD | NADH peroxidase | 1.11.1.1 | 0.855 | |
| 4j56 | FAD | Thioredoxin reductase 2 | 1.8.1.9 | 0.854 | |
| 3ic9 | FAD | Putative dihydrolipoamide dehydrogenase | / | 0.852 | |
| 4opi | FDA | Conserved Archaeal protein | / | 0.852 | |
| 1lpf | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.850 | |
| 2qae | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.846 | |
| 2yqu | FAD | Dihydrolipoyl dehydrogenase | / | 0.846 | |
| 1fea | FAD | Trypanothione reductase | 1.8.1.12 | 0.845 | |
| 2w0h | FAD | Trypanothione reductase | / | 0.843 | |
| 3nta | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.841 | |
| 1nhq | FAD | NADH peroxidase | 1.11.1.1 | 0.840 | |
| 3ef6 | FAD | Toluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component | 1.18.1.3 | 0.838 | |
| 3urh | FAD | Dihydrolipoyl dehydrogenase | / | 0.838 | |
| 1mok | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.836 | |
| 5fs8 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.836 | |
| 1zmc | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.834 | |
| 4j36 | FAD | Kynurenine 3-monooxygenase | / | 0.834 | |
| 3lzw | FAD | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.833 | |
| 2c3d | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.832 | |
| 4dna | FAD | Probable glutathione reductase | / | 0.831 | |
| 1jeh | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.829 | |
| 4bjz | FAD | Probable salicylate monooxygenase | / | 0.828 | |
| 4j31 | FAD | Kynurenine 3-monooxygenase | / | 0.826 | |
| 3atq | FDA | Conserved Archaeal protein | / | 0.824 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.823 | |
| 3ab1 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.819 | |
| 4j34 | FAD | Kynurenine 3-monooxygenase | / | 0.819 | |
| 1typ | FAD | Trypanothione reductase | 1.8.1.12 | 0.818 | |
| 2a8x | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.817 | |
| 3oz2 | FAD | Digeranylgeranylglycerophospholipid reductase | / | 0.817 | |
| 3oc4 | FAD | Oxidoreductase, pyridine nucleotide-disulfide family | / | 0.816 | |
| 4opl | FDA | Conserved Archaeal protein | / | 0.815 | |
| 5buk | FAD | FADH2-dependent halogenase | / | 0.815 | |
| 4opd | FDA | Conserved Archaeal protein | / | 0.814 | |
| 4fx9 | FAD | Coenzyme A disulfide reductase | 1.8.1.14 | 0.812 | |
| 4opc | FDA | Conserved Archaeal protein | / | 0.812 | |
| 1lvl | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.811 | |
| 4hb9 | FAD | Uncharacterized protein | / | 0.811 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.811 | |
| 3lzx | FAD | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.810 | |
| 3all | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.804 | |
| 4bk2 | FAD | Probable salicylate monooxygenase | / | 0.804 | |
| 2q0k | FAD | Thioredoxin reductase | 1.8.1.9 | 0.803 | |
| 2j3n | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.801 | |
| 3cgc | FAD | Coenzyme A disulfide reductase | / | 0.801 | |
| 3ntd | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.800 | |
| 4j33 | FAD | Kynurenine 3-monooxygenase | / | 0.800 | |
| 1trb | FAD | Thioredoxin reductase | 1.8.1.9 | 0.798 | |
| 4eqx | FAD | Coenzyme A disulfide reductase | / | 0.798 | |
| 4gcm | FAD | Thioredoxin reductase | 1.8.1.9 | 0.796 | |
| 5fs9 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.796 | |
| 1tyt | FAD | Trypanothione reductase | 1.8.1.12 | 0.794 | |
| 2i0z | FAD | NAD(FAD)-utilizing dehydrogenases | / | 0.793 | |
| 2qa1 | FAD | PgaE | / | 0.793 | |
| 4m52 | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.793 | |
| 4cnk | FAD | L-amino acid oxidase | / | 0.792 | |
| 3cty | FAD | Probable thioredoxin reductase | / | 0.791 | |
| 4ocg | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.791 | |
| 4em3 | FAD | Coenzyme A disulfide reductase | / | 0.790 | |
| 5fs7 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.789 | |
| 3ict | FAD | Coenzyme A disulfide reductase | / | 0.787 | |
| 4fwj | FAD | Lysine-specific histone demethylase 1B | 1 | 0.787 | |
| 1mo9 | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.786 | |
| 5g3s | FDA | Flavin-dependent L-tryptophan oxidase VioA | / | 0.786 | |
| 4opu | FDA | Conserved Archaeal protein | / | 0.782 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.780 | |
| 4em4 | FAD | Coenzyme A disulfide reductase | / | 0.780 | |
| 4lii | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.780 | |
| 3f8d | FAD | NADH oxidase/thioredoxin reductase | / | 0.779 | |
| 4eqw | FAD | Coenzyme A disulfide reductase | / | 0.779 | |
| 4g6h | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.777 | |
| 4nte | FAD | DepH | / | 0.776 | |
| 4rsl | FAD | Fructosyl peptide oxidase | / | 0.775 | |
| 1tde | FAD | Thioredoxin reductase | 1.8.1.9 | 0.774 | |
| 2q7v | FAD | Thioredoxin reductase | / | 0.773 | |
| 4k5r | FAD | Oxygenase | / | 0.772 | |
| 1joa | FAD | NADH peroxidase | 1.11.1.1 | 0.771 | |
| 1yqz | FAD | Coenzyme A disulfide reductase | / | 0.767 | |
| 4bv6 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.767 | |
| 4o5u | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.765 | |
| 3atr | FDA | Conserved Archaeal protein | / | 0.764 | |
| 4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.764 | |
| 4eqr | FAD | Coenzyme A disulfide reductase | / | 0.763 | |
| 4k2x | FAD | Polyketide oxygenase/hydroxylase | / | 0.763 | |
| 3fbs | FAD | Oxidoreductase | / | 0.762 | |
| 1ojt | FAD | Dihydrolipoyl dehydrogenase | / | 0.761 | |
| 1tdf | FAD | Thioredoxin reductase | 1.8.1.9 | 0.760 | |
| 1zy8 | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.760 | |
| 2bab | FAD | Putative aminooxidase | / | 0.760 | |
| 4fwe | FAD | Lysine-specific histone demethylase 1B | 1 | 0.758 | |
| 2v3a | FAD | Rubredoxin-NAD(+) reductase | 1.18.1.1 | 0.757 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.757 | |
| 4x4j | FAD | Putative oxygenase | / | 0.757 | |
| 5eow | FAD | 6-hydroxynicotinate 3-monooxygenase | 1.14.13.114 | 0.757 | |
| 1xdi | FAD | NAD(P)H dehydrogenase (quinone) | / | 0.756 | |
| 1tdk | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.754 | |
| 3cgb | FAD | Coenzyme A disulfide reductase | / | 0.754 | |
| 4gut | FAD | Lysine-specific histone demethylase 1B | 1 | 0.752 | |
| 4hsu | FAD | Lysine-specific histone demethylase 1B | 1 | 0.752 | |
| 1d7l | RFL | p-hydroxybenzoate hydroxylase | / | 0.751 | |
| 1tdn | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.751 | |
| 3rha | FDA | Putrescine oxidase | / | 0.751 | |
| 3ad9 | FAD | Subunit beta of sarcosine oxidase | / | 0.750 | |
| 1yy5 | FAD | Polyamine oxidase FMS1 | / | 0.748 | |
| 4eqs | FAD | Coenzyme A disulfide reductase | / | 0.748 | |
| 4jy2 | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.747 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.746 | |
| 2vou | FAD | 2,6-dihydroxypyridine 3-monooxygenase | 1.14.13.10 | 0.745 | |
| 3ish | FAD | Thioredoxin reductase | 1.8.1.9 | 0.745 | |
| 4dsh | FDA | Uncharacterized protein | / | 0.745 | |
| 2yg4 | FAD | Putrescine oxidase | / | 0.744 | |
| 4a5l | FAD | Thioredoxin reductase | / | 0.744 | |
| 4cbq | FAD | Thioredoxin reductase | / | 0.744 | |
| 4j2w | FAD | Kynurenine 3-monooxygenase | / | 0.744 | |
| 4ntd | FAD | Thioredoxin reductase | / | 0.744 | |
| 2zbw | FAD | Ferredoxin--NADP reductase | / | 0.743 | |
| 2qa2 | FAD | Polyketide oxygenase CabE | / | 0.742 | |
| 4jn9 | FAD | DepH | / | 0.742 | |
| 4xwz | FAD | Fructosyl amine:oxygen oxidoreductase | / | 0.742 | |
| 1reo | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.740 | |
| 3axb | FAD | Putative oxidoreductase | / | 0.740 | |
| 2dw4 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.739 | |
| 4ccq | FAD | Thioredoxin reductase | / | 0.739 | |
| 4up3 | FAD | Thioredoxin reductase | / | 0.739 | |
| 1tdo | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.738 | |
| 4u2t | FAD | Cholesterol oxidase | 1.1.3.6 | 0.737 | |
| 1gv4 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.736 | |
| 2jb1 | FAD | L-amino acid oxidase | / | 0.736 | |
| 2xdo | FAD | TetX family tetracycline inactivation enzyme | / | 0.736 | |
| 3cnt | FAD | Polyamine oxidase FMS1 | / | 0.736 | |
| 3k7m | FAD | 6-hydroxy-L-nicotine oxidase | / | 0.736 | |
| 4bur | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.736 | |
| 2bac | FAD | Putative aminooxidase | / | 0.733 | |
| 3cge | FAD | Coenzyme A disulfide reductase | / | 0.731 | |
| 3gmb | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.731 | |
| 3rp8 | FAD | FAD-dependent urate hydroxylase | / | 0.731 | |
| 2gr3 | FAD | Ferredoxin reductase | / | 0.730 | |
| 3bi5 | FAD | Polyamine oxidase FMS1 | / | 0.730 | |
| 4bk3 | FAD | Probable salicylate monooxygenase | / | 0.730 | |
| 4rek | FAD | Cholesterol oxidase | 1.1.3.6 | 0.730 | |
| 4ynt | FDA | Glucose oxidase, putative | / | 0.730 | |
| 5dbj | FAD | FADH2-dependent halogenase PltA | / | 0.729 | |
| 1d7y | FAD | Ferredoxin reductase | / | 0.728 | |
| 3qvr | FAD | Glucose oxidase | 1.1.3.4 | 0.728 | |
| 4h2n | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.728 | |
| 4ykf | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.728 | |
| 5g3t | FDA | Flavin-dependent L-tryptophan oxidase VioA | / | 0.728 | |
| 1gte | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.727 | |
| 1gth | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.727 | |
| 1h7w | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.727 | |
| 3itj | FAD | Thioredoxin reductase 1 | 1.8.1.9 | 0.727 | |
| 4o5q | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.726 | |
| 5j60 | FAD | Thioredoxin reductase | / | 0.726 | |
| 1n4u | FAE | Cholesterol oxidase | 1.1.3.6 | 0.725 | |
| 3cgd | FAD | Coenzyme A disulfide reductase | / | 0.723 | |
| 3m12 | FAD | Monomeric sarcosine oxidase | 1.5.3.1 | 0.723 | |
| 5l3d | FAD | Lysine-specific histone demethylase 1A | 1 | 0.723 | |
| 1k0j | FAD | p-hydroxybenzoate hydroxylase | / | 0.722 | |
| 1m6i | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.722 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.722 | |
| 4gus | FAD | Lysine-specific histone demethylase 1B | 1 | 0.722 | |
| 3t37 | FAD | Pyridoxine 4-oxidase | / | 0.721 | |
| 2jae | FAD | L-amino acid oxidase | / | 0.720 | |
| 4ykg | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.720 | |
| 2c4c | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.719 | |
| 3gyi | FAD | Cholesterol oxidase | 1.1.3.6 | 0.719 | |
| 3gyj | FAD | Cholesterol oxidase | 1.1.3.6 | 0.719 | |
| 4emj | FAD | Toluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component | 1.18.1.3 | 0.719 | |
| 1b4v | FAD | Cholesterol oxidase | 1.1.3.6 | 0.718 | |
| 2b9y | FAD | Putative aminooxidase | / | 0.718 | |
| 4ntc | FAD | Thioredoxin reductase gliT | / | 0.718 | |
| 2b9x | FAD | Putative aminooxidase | / | 0.717 | |
| 2yg7 | FAD | Putrescine oxidase | / | 0.716 | |
| 4cy8 | FDA | 2-hydroxybiphenyl-3-monooxygenase | / | 0.716 | |
| 4h2p | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.716 | |
| 1v0j | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.715 | |
| 3sgl | FAD | tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC | / | 0.715 | |
| 4c5o | FAD | Putative monooxygenase | / | 0.715 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.714 | |
| 2gew | FAD | Cholesterol oxidase | 1.1.3.6 | 0.714 | |
| 3alj | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.714 | |
| 3klj | FAD | NADH-rubredoxin oxidoreductase | 1.18.1.1 | 0.714 | |
| 4a65 | FAD | Thioredoxin reductase | / | 0.714 | |
| 4xwr | FAD | Cholesterol oxidase | 1.1.3.6 | 0.711 | |
| 1jnr | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.710 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.710 | |
| 3m13 | FAD | Monomeric sarcosine oxidase | 1.5.3.1 | 0.709 | |
| 3pl8 | FAD | Pyranose 2-oxidase | / | 0.709 | |
| 3vqr | FAD | Putative oxidoreductase | / | 0.709 | |
| 2whd | FAD | Thioredoxin reductase | / | 0.708 | |
| 3alm | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.708 | |
| 3bg7 | FAD | Pyranose 2-oxidase | / | 0.708 | |
| 3ept | FDA | Putative FAD-monooxygenase | / | 0.708 | |
| 4gur | FAD | Lysine-specific histone demethylase 1B | 1 | 0.708 | |
| 2e1m | FAD | L-glutamate oxidase | / | 0.707 | |
| 4ccr | FAD | Thioredoxin reductase | / | 0.707 | |
| 1ng4 | FAD | Glycine oxidase | 1.4.3.19 | 0.706 | |
| 2ign | FAD | Pyranose 2-oxidase | / | 0.706 | |
| 1rsg | FAD | Polyamine oxidase FMS1 | / | 0.705 | |
| 1y56 | FAD | 382aa long hypothetical sarcosine oxidase | / | 0.705 | |
| 1z6l | FAD | Polyamine oxidase FMS1 | / | 0.705 | |
| 3k4c | FAD | Pyranose 2-oxidase | / | 0.705 | |
| 3sm8 | FNK | FAD-dependent catabolic D-arginine dehydrogenase DauA | / | 0.705 | |
| 4h4z | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.705 | |
| 2gr0 | FAD | Ferredoxin reductase | / | 0.704 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.704 | |
| 4opt | FDA | Conserved Archaeal protein | / | 0.704 | |
| 2cdu | FAD | NADH oxidase | / | 0.703 | |
| 3fmw | FAD | Oxygenase | / | 0.703 | |
| 4g9k | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.703 | |
| 1fl2 | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.702 | |
| 3zdn | FAD | Monoamine oxidase N | 1.4.3.4 | 0.702 | |
| 4g74 | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.702 | |
| 2b9w | FAD | Putative aminooxidase | / | 0.701 | |
| 2yg6 | FAD | Putrescine oxidase | / | 0.701 | |
| 3mj4 | FAD | UDP-galactopyranose mutase | / | 0.701 | |
| 4cnj | FAD | L-amino acid oxidase | / | 0.701 | |
| 1cc2 | FAD | Cholesterol oxidase | 1.1.3.6 | 0.699 | |
| 1ps9 | FAD | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.699 | |
| 3fg2 | FAD | Putative rubredoxin reductase | / | 0.699 | |
| 3lsh | FAD | Pyranose 2-oxidase | / | 0.699 | |
| 4h4t | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.699 | |
| 4u8k | FDA | UDP-galactopyranose mutase | / | 0.699 | |
| 4wct | FAD | Fructosyl amine:oxygen oxidoreductase | / | 0.698 | |
| 4yjd | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.698 | |
| 1b8s | FAD | Cholesterol oxidase | 1.1.3.6 | 0.697 | |
| 1vdc | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.697 | |
| 2yvf | FAD | Ferredoxin reductase | / | 0.697 | |
| 3m0o | FAD | Monomeric sarcosine oxidase | 1.5.3.1 | 0.697 | |
| 1wam | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.696 | |
| 5fs6 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.696 | |
| 1f3p | FAD | Ferredoxin reductase | / | 0.695 | |
| 2fjd | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.695 | |
| 3cnj | FAD | Cholesterol oxidase | 1.1.3.6 | 0.695 | |
| 3lb8 | FAD | Putidaredoxin reductase | 1.18.1.5 | 0.695 | |
| 3nt6 | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.695 | |
| 5eb5 | FAD | (R)-mandelonitrile lyase 1 | 4.1.2.10 | 0.695 | |
| 1e1k | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.693 | |
| 4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.693 | |
| 1n4v | FAD | Cholesterol oxidase | 1.1.3.6 | 0.692 | |
| 2gqw | FAD | Ferredoxin reductase | / | 0.692 | |
| 3lxd | FAD | FAD-dependent pyridine nucleotide-disulfide oxidoreductase | / | 0.692 | |
| 1kif | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.691 | |
| 3ka7 | FAD | Putative oxidoreductase | / | 0.691 | |
| 4gap | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.691 | |
| 3kve | FAD | L-amino-acid oxidase | / | 0.690 | |
| 4h4r | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.690 | |
| 4h4v | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.690 | |
| 4h4x | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.690 | |
| 4i58 | FAD | Cyclohexylamine Oxidase | / | 0.690 | |
| 4h4p | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.689 | |
| 1ijh | FAD | Cholesterol oxidase | 1.1.3.6 | 0.688 | |
| 1lqu | FAD | NADPH-ferredoxin reductase FprA | 1.18.1.2 | 0.688 | |
| 2yg3 | FAD | Putrescine oxidase | / | 0.688 | |
| 2bi8 | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.687 | |
| 3ukf | FDA | UDP-galactopyranose mutase | / | 0.687 | |
| 4dsg | FAD | Uncharacterized protein | / | 0.687 | |
| 2cvj | FAD | Thioredoxin reductase related protein | / | 0.686 | |
| 3ad9 | NAD | Subunit alpha of sarocosine oxidase | / | 0.686 | |
| 3f8r | NAP | NADH oxidase/thioredoxin reductase | / | 0.686 | |
| 3lsi | FAD | Pyranose 2-oxidase | / | 0.686 | |
| 4z2t | FAD | 2-hydroxybiphenyl-3-monooxygenase | / | 0.686 | |
| 1q1w | FAD | Putidaredoxin reductase | 1.18.1.5 | 0.685 | |
| 2pr5 | FMN | Blue-light photoreceptor | / | 0.685 | |
| 3lsm | SFD | Pyranose 2-oxidase | / | 0.685 | |
| 1cl0 | FAD | Thioredoxin reductase | 1.8.1.9 | 0.684 | |
| 2iid | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.684 | |
| 2vvl | FAD | Monoamine oxidase N | 1.4.3.4 | 0.683 | |
| 3int | FDA | UDP-galactopyranose mutase | 5.4.99.9 | 0.683 | |
| 1d4d | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.682 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.682 | |
| 3nix | FAD | Flavoprotein/dehydrogenase | / | 0.681 | |
| 4usr | FAD | Monooxygenase | / | 0.681 | |
| 4xxg | FAD | Cholesterol oxidase | 1.1.3.6 | 0.681 | |
| 2rgh | FAD | Alpha-Glycerophosphate Oxidase | / | 0.680 | |
| 3cox | FAD | Cholesterol oxidase | 1.1.3.6 | 0.679 | |
| 3hdy | FAD | UDP-galactopyranose mutase | / | 0.679 | |
| 3kyb | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.679 | |
| 3p9u | FAD | TetX family tetracycline inactivation enzyme | / | 0.679 | |
| 2yg5 | FAD | Putrescine oxidase | / | 0.678 | |
| 5hxw | FAD | L-amino acid deaminase | / | 0.678 | |
| 2fje | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.677 | |
| 1n1p | FAD | Cholesterol oxidase | 1.1.3.6 | 0.676 | |
| 1n4w | FAD | Cholesterol oxidase | 1.1.3.6 | 0.676 | |
| 1phh | FAD | p-hydroxybenzoate hydroxylase | / | 0.676 | |
| 2fjb | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.676 | |
| 2jb2 | FAD | L-amino acid oxidase | / | 0.675 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.675 | |
| 3c4a | FAD | Protodeoxyviolaceinate monooxygenase | 1 | 0.675 | |
| 4gde | FDA | UDP-galactopyranose mutase | / | 0.675 | |
| 4u8j | FDA | UDP-galactopyranose mutase | / | 0.675 | |
| 2ywl | FAD | Thioredoxin reductase related protein | / | 0.674 | |
| 3qj4 | FAD | Renalase | / | 0.674 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.674 | |
| 4gav | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.674 | |
| 4mok | FAD | Pyranose 2-oxidase | / | 0.674 | |
| 3d8x | FAD | Thioredoxin reductase 1 | 1.8.1.9 | 0.673 | |
| 4gdp | FAD | Polyamine oxidase FMS1 | / | 0.673 | |
| 4u8l | FDA | UDP-galactopyranose mutase | / | 0.673 | |
| 4a6n | FAD | TetX family tetracycline inactivation enzyme | / | 0.672 | |
| 4jnq | FDA | Thioredoxin reductase | / | 0.672 | |
| 1e1m | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.671 | |
| 3cnd | FAD | Polyamine oxidase FMS1 | / | 0.671 | |
| 4eep | FMN | Phototropin-2 | 2.7.11.1 | 0.671 | |
| 4guv | FAD | TetX family tetracycline inactivation enzyme | / | 0.671 | |
| 1q1r | FAD | Putidaredoxin reductase | 1.18.1.5 | 0.670 | |
| 3k4n | FAD | Pyranose 2-oxidase | / | 0.670 | |
| 3uth | FDA | UDP-galactopyranose mutase | / | 0.670 | |
| 4icy | FAD | PgaE | / | 0.670 | |
| 4yxd | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.670 | |
| 3nyc | FAD | FAD-dependent catabolic D-arginine dehydrogenase DauA | / | 0.669 | |
| 3utf | FDA | UDP-galactopyranose mutase | / | 0.668 | |
| 4hia | FMN | LOV protein | / | 0.668 | |
| 4x9m | FAD | Uncharacterized protein MG039 homolog | / | 0.668 | |
| 5i39 | FAD | L-amino acid deaminase | / | 0.668 | |
| 3lov | FAD | Protoporphyrinogen oxidase | / | 0.667 | |
| 5br7 | FAD | UDP-galactopyranose mutase | / | 0.667 | |
| 4u8i | FDA | UDP-galactopyranose mutase | / | 0.666 | |
| 1k0l | FAD | p-hydroxybenzoate hydroxylase | / | 0.665 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.665 | |
| 5ez7 | FAD | Probable FAD-dependent oxidoreductase PA4991 | / | 0.665 | |
| 1gal | FAD | Glucose oxidase | 1.1.3.4 | 0.664 | |
| 2q0l | FAD | Thioredoxin reductase | 1.8.1.9 | 0.664 | |
| 2uxx | FAJ | Lysine-specific histone demethylase 1A | 1 | 0.664 | |
| 3kpf | FAD | Polyamine oxidase | 1.5.3.14 | 0.664 | |
| 5er0 | FAD | Uncharacterized NAD(FAD)-dependent dehydrogenase | / | 0.664 | |
| 1ep3 | FAD | Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit | / | 0.663 | |
| 1jnz | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.663 | |
| 3pvc | FAD | tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC | / | 0.663 | |
| 4g6g | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.663 | |
| 2xyo | FAD | TetX family tetracycline inactivation enzyme | / | 0.662 | |
| 3nn6 | FB0 | 6-hydroxy-L-nicotine oxidase | / | 0.662 | |
| 1kf6 | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.660 | |
| 2yr5 | FAD | Phenylalanine 2-monooxygenase precursor | 1.13.12.9 | 0.660 | |
| 3dme | FAD | Putative conserved exported protein | / | 0.660 | |
| 4h4u | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.660 | |
| 1cbo | FAD | Cholesterol oxidase | 1.1.3.6 | 0.659 | |
| 3l8k | ADP | Dihydrolipoamide dehydrogenase (PdhD-3) | / | 0.659 | |
| 3s5w | FAD | L-ornithine N(5)-monooxygenase | / | 0.659 | |
| 4c3y | FAD | 3-ketosteroid dehydrogenase | / | 0.659 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.659 | |
| 4u8p | FDA | UDP-galactopyranose mutase | / | 0.659 | |
| 5c3j | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.659 | |
| 3k30 | ADP | Histamine dehydrogenase | / | 0.658 | |
| 4aox | FAD | Steroid monooxygenase | / | 0.658 | |
| 3gsi | FAD | Dimethylglycine oxidase | 1.5.3.10 | 0.657 | |
| 4udr | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.657 | |
| 4wx1 | FDA | UDP-galactopyranose mutase | / | 0.657 | |
| 1ve9 | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.656 | |
| 2iw5 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.656 | |
| 3q9t | FAY | Uncharacterized protein | / | 0.656 | |
| 3sfe | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.656 | |
| 4tm3 | FAD | KtzI | / | 0.656 | |
| 1mxt | FAE | Cholesterol oxidase | 1.1.3.6 | 0.655 | |
| 3he3 | FAD | UDP-galactopyranose mutase | / | 0.655 | |
| 3k7t | FAD | 6-hydroxy-L-nicotine oxidase | / | 0.655 | |
| 2gv8 | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.654 | |
| 3b6d | FAE | Cholesterol oxidase | 1.1.3.6 | 0.654 | |
| 3f8p | NAD | NADH oxidase/thioredoxin reductase | / | 0.654 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.654 | |
| 1f8s | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.653 | |
| 3if9 | FAD | Glycine oxidase | 1.4.3.19 | 0.653 | |
| 4rpg | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.653 | |
| 4u8m | FDA | UDP-galactopyranose mutase | / | 0.653 | |
| 2fja | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.651 | |
| 3sz0 | FAD | Sulfide-quinone reductase | / | 0.651 | |
| 1djn | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.650 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.650 | |
| 2tmd | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.650 | |
| 3gd3 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.650 |