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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4x8oAP5Adenylate kinase

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
4x8oAP5Adenylate kinase/1.000
3hpqAP5Adenylate kinase/0.647
3dkvAP5Adenylate kinase/0.626
1akeAP5Adenylate kinase/0.622
1ankANPAdenylate kinase/0.620
2eckADPAdenylate kinase/0.615
4nu0AP5Adenylate kinase/0.610
4qbiAP5Adenylate kinase/0.605
2oo7AP5Adenylate kinase/0.593
1p3jAP5Adenylate kinase/0.571
1e4yAP5Adenylate kinase/0.564
2akyAP5Adenylate kinase/0.559
4qbhAP5Adenylate kinase/0.553
4x8lAP5Adenylate kinase/0.547
4cf7ADPAdenylate kinase/0.543
4jl6ADPAdenylate kinase/0.542
2rgxAP5Adenylate kinase/0.534
1esvLARActin, alpha skeletal muscle/0.522
2olrATPPhosphoenolpyruvate carboxykinase (ATP)/0.522
2py7ATPPhosphoenolpyruvate carboxykinase (ATP)/0.511
2iypA2P6-phosphogluconate dehydrogenase, decarboxylating1.1.1.440.496
1y57MPZProto-oncogene tyrosine-protein kinase Src2.7.10.20.495
4mkhAP5Adenylate kinase/0.495
4yp12BAStimulator of interferon genes protein/0.494
3lovFADProtoporphyrinogen oxidase/0.493
4paoGSPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.492
1kvsUPGUDP-glucose 4-epimerase5.1.3.20.490
3fql79ZGenome polyprotein2.7.7.480.490
4z17PEPEnolase/0.489
2vcmM11Isopenicillin N synthase1.21.3.10.488
2yx6ADPUncharacterized protein/0.487
5dbyNPSSerum albumin/0.487
1qjfACSIsopenicillin N synthase1.21.3.10.485
2x0rNADMalate dehydrogenase/0.485
2yvfNADFerredoxin reductase/0.485
3ed1GA3Gibberellin receptor GID1/0.485
4kq21S3Glycogen [starch] synthase isoform 22.4.1.110.484
4zohFADPutative oxidoreductase FAD-binding subunit/0.484
4dpwAGSMevalonate diphosphate decarboxylase/0.483
2cgpCMPcAMP-activated global transcriptional regulator CRP/0.482
4fv7E94Mitogen-activated protein kinase 12.7.11.240.482
4mkfAP5Adenylate kinase/0.482
1sd1FMCS-methyl-5'-thioadenosine phosphorylase/0.481
2gmvPEPPhosphoenolpyruvate carboxykinase, cytosolic [GTP]4.1.1.320.481
4kq2U5PGlycogen [starch] synthase isoform 22.4.1.110.481
2v3aFADRubredoxin-NAD(+) reductase1.18.1.10.479
4hj4FMNLOV protein/0.478
1f9aATPNicotinamide-nucleotide adenylyltransferase/0.477
1z5cADPType 2 DNA topoisomerase 6 subunit B/0.477
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.477
3hadNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.477
4qms1N1Serine/threonine-protein kinase 242.7.11.10.477
1ytmATPPhosphoenolpyruvate carboxykinase (ATP)/0.476
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.476
4x30T44Thyroxine-binding globulin/0.476
1g9cBABBotulinum neurotoxin type B3.4.24.690.475
2g78REACellular retinoic acid-binding protein 2/0.475
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.475
4wucANPDNA gyrase subunit B/0.475
1pn3TYDdTDP-epi-vancosaminyltransferase2.4.1.3110.474
2b69NADUDP-glucuronic acid decarboxylase 14.1.1.350.474
4v02ATPSite-determining protein/0.474
5kghACOPredicted acetyltransferase/0.474
2qtvGNPSmall COPII coat GTPase SAR13.6.50.473
4loh1SYStimulator of interferon genes protein/0.473
2zbaZBATrichothecene 3-O-acetyltransferase/0.472
4ho4THMGlucose-1-phosphate thymidylyltransferase/0.472
2z6cFMNPhototropin-12.7.11.10.471
3bv2P38Mitogen-activated protein kinase 14/0.471
4hnbFMNLOV protein/0.471
4u0mGTPCyclic GMP-AMP synthase/0.471
5kgpACOPredicted acetyltransferase/0.471
1dliUDXUDP-glucose 6-dehydrogenase/0.470
3umsGDPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.470
4i8x6P3L-lactate dehydrogenase A chain1.1.1.270.470
2bunFADAppA protein/0.469
4ztvTA7Anthranilate phosphoribosyltransferase/0.469
1v9aSAHUncharacterized protein/0.468
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.468
4du82P0Mevalonate diphosphate decarboxylase/0.468
4f5dC2EStimulator of interferon genes protein/0.468
4h0yLARActin, alpha skeletal muscle/0.468
3fgoACPSarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.467
3t58FADSulfhydryl oxidase 11.8.3.20.467
3vhxGTPADP-ribosylation factor 6/0.467
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.467
4h2nFAD2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase/0.467
4xey1N1Tyrosine-protein kinase ABL12.7.10.20.467
4xgxADPFAD:protein FMN transferase/0.467
1d7aAIRN5-carboxyaminoimidazole ribonucleotide mutase/0.466
1xelUPGUDP-glucose 4-epimerase5.1.3.20.466
3nl6TPSUncharacterized protein/0.466
4e07ACPPlasmid partitioning protein ParF/0.466
4jkyADPAdenylate kinase/0.466
4prxADPDNA gyrase subunit B/0.466
1fm7DFVChalcone--flavonone isomerase 15.5.1.60.465
1v59NADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.465
1xq6NAPUncharacterized protein At5g02240/0.465
3gfeP37Mitogen-activated protein kinase 14/0.465
3ibqATPPyridoxal kinase/0.465
3q5kD1UHeat shock protein 83-1/0.465
4jldADPAdenylate kinase/0.465
5fknTDCTetracycline repressor protein class D/0.465
1ju9NADAlcohol dehydrogenase E chain1.1.1.10.464
1zd9GDPADP-ribosylation factor-like protein 8A/0.464
2ddoATPPyridoxine/pyridoxal/pyridoxamine kinase/0.464
3cluFADElectron transfer flavoprotein subunit alpha/0.464
3r0tFU9Casein kinase II subunit alpha2.7.11.10.464
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.464
4hy6FJ1Heat shock protein HSP 90-alpha/0.464
4kukRBFPutative blue-light photoreceptor/0.464
4xyeNADFormate dehydrogenase/0.464
5cnsCDPRibonucleoside-diphosphate reductase 1 subunit alpha1.17.4.10.464
1i2cUPGUDP-sulfoquinovose synthase, chloroplastic3.13.1.10.463
1tqf32PBeta-secretase 13.4.23.460.463
2ag1TPPBenzaldehyde lyase/0.463
2bueCOAAAC(6')-Ib/0.463
2imkGTXAGAP009194-PA/0.463
3dv3MEKDual specificity mitogen-activated protein kinase kinase 12.7.12.20.463
4e09ACPPlasmid partitioning protein ParF/0.463
4m4922YL-lactate dehydrogenase A chain1.1.1.270.463
1ia1NDPDihydrofolate reductase1.5.1.30.462
1l7eNAINAD(P) transhydrogenase subunit alpha part 11.6.1.20.462
1rc1KT3Trifunctional purine biosynthetic protein adenosine-32.1.2.20.462
3clyACPFibroblast growth factor receptor 2/0.462
3u11CMPPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4/0.462
4cnzADPNitrogen regulatory protein P-II 1/0.462
4eesFMNPhototropin-22.7.11.10.462
4jloADPAdenylate kinase/0.462
5kczNAJAlcohol dehydrogenase E chain1.1.1.10.462
1k27MTMS-methyl-5'-thioadenosine phosphorylase/0.461
1nhhANPDNA mismatch repair protein MutL/0.461
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.461
1x2hLPALipoate-protein ligase A6.3.1.200.461
1zrzBI1Protein kinase C iota type2.7.11.130.461
2emuSAHDiphthine synthase/0.461
2vbpVB1Isopenicillin N synthase1.21.3.10.461
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
3oibFDAPutative acyl-CoA dehydrogenase/0.461
4r38RBFBlue-light-activated histidine kinase 22.7.13.30.461
4z69DIFSerum albumin/0.461
1cg6MTAS-methyl-5'-thioadenosine phosphorylase/0.460
1gq2NAPNADP-dependent malic enzyme1.1.1.400.460
1oonFMNOxygen-insensitive NAD(P)H nitroreductase/0.460
1z0dGDPRas-related protein Rab-5C/0.460
2briANPUridylate kinase2.7.4.220.460
2jlbUDMUncharacterized protein/0.460
2w9hTOPDihydrofolate reductase1.5.1.30.460
3lfa1N1Mitogen-activated protein kinase 14/0.460
4bqpNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.460
4d5gFADCyclohexane-1,2-dione hydrolase3.7.1.110.460
1iayAVG1-aminocyclopropane-1-carboxylate synthase 24.4.1.140.459
2bfrADP[Protein ADP-ribosylglutamate] hydrolase AF_15213.2.20.459
3lmgANPReceptor tyrosine-protein kinase erbB-32.7.10.10.459
3n8nN883-dehydroquinate dehydratase4.2.1.100.459
3oafOAGDihydrofolate reductase1.5.1.30.459
4f6w0SSCyclin-dependent kinase 82.7.11.220.459
2oz6CMPCyclic AMP receptor-like protein/0.458
2qo9ANPEphrin type-A receptor 32.7.10.10.458
3pvwQRXBeta-adrenergic receptor kinase 12.7.11.150.458
3vaqADNPutative adenosine kinase/0.458
4fvqATPTyrosine-protein kinase JAK2/0.458
4lb2DM5Serum albumin/0.458
5a8aFMNRiboflavin biosynthesis protein RibF2.7.1.260.458
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.457
2itwITQEpidermal growth factor receptor2.7.10.10.457
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.457
2q4bNAPUncharacterized protein At5g02240/0.457
2x0iNAIMalate dehydrogenase/0.457
3pcnDHYProtocatechuate 3,4-dioxygenase alpha chain1.13.11.30.457
3pcnDHYProtocatechuate 3,4-dioxygenase beta chain1.13.11.30.457
4fxy0W2Neurolysin, mitochondrial3.4.24.160.457
4iacACPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.457
4n57ADPAPH(2'')-Id/0.457
4o1bDGBNicotinamide phosphoribosyltransferase2.4.2.120.457
4u0oMTALipoyl synthase 2/0.457
1ykdCMPAdenylate cyclase/0.456
2c31TZDOxalyl-CoA decarboxylase4.1.1.80.456
2cbsR13Cellular retinoic acid-binding protein 2/0.456
2ch6ADPN-acetyl-D-glucosamine kinase2.7.1.590.456
2ydxNAPMethionine adenosyltransferase 2 subunit beta/0.456
3b9lAZZSerum albumin/0.456
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.456
3itzP66Mitogen-activated protein kinase 14/0.456
3oq6NAJAlcohol dehydrogenase E chain1.1.1.10.456
3otfCMPPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4/0.456
3pghFLPProstaglandin G/H synthase 21.14.99.10.456
3td7FADProbable FAD-linked sulfhydryl oxidase R5961.8.3.20.456
4gyzD5MTyrosyl-DNA phosphodiesterase 23.1.40.456
4ku2MYA3-oxoacyl-[ACP] synthase III/0.456
4panGDPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.456
4uocNCNCinA-like protein/0.456
1il0NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.455
1lsjNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.455
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.455
2f02ATPTagatose-6-phosphate kinase/0.455
2nomDUTPoly(A) polymerase, putative/0.455
2ooyATP5'-AMP-activated protein kinase subunit gamma/0.455
2owkSAHDiphthine synthase/0.455
3ac2KSETyrosine-protein kinase Lck2.7.10.20.455
3kjiADPCO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC/0.455
3qt62P0Mevalonate diphosphate decarboxylase/0.455
3sxnCOAN-acetyltransferase Eis/0.455
4c72TLG3-oxoacyl-ACP synthase/0.455
4d04NAPPhenylacetone monooxygenase1.14.13.920.455
4h4wNAPBiphenyl dioxygenase ferredoxin reductase subunit/0.455
4ho6UTPGlucose-1-phosphate thymidylyltransferase/0.455
4r1lADPPhenylacetate-coenzyme A ligase/0.455
1dbvNADGlyceraldehyde-3-phosphate dehydrogenase/0.454
1pjcNADAlanine dehydrogenase/0.454
1wuuANPGalactokinase2.7.1.60.454
2q46NAPUncharacterized protein At5g02240/0.454
2qhn582Serine/threonine-protein kinase Chk12.7.11.10.454
3s1dZIRCytokinin dehydrogenase 11.5.99.120.454
3stxBKAMethylketone synthase I/0.454
3zcxNADGlyceraldehyde-3-phosphate dehydrogenase/0.454
4n49MGTCap-specific mRNA (nucleoside-2'-O-)-methyltransferase 12.1.1.570.454
1jnkANPMitogen-activated protein kinase 102.7.11.240.453
2p5cSAHDiphthine synthase/0.453
2p6iSAHDiphthine synthase/0.453
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.453
3e8xNAPBH1520 protein/0.453
3elm24FCollagenase 33.4.240.453
3gfzFMNUncharacterized protein/0.453
3qlrNDPDihydrofolate reductase1.5.1.30.453
4ajj88RL-lactate dehydrogenase A chain1.1.1.270.453
4bdfH3RSerine/threonine-protein kinase Chk22.7.11.10.453
4dpy2P0Mevalonate diphosphate decarboxylase/0.453
4dqwATPInosine-5'-monophosphate dehydrogenase/0.453
4eo3FMNBacterioferritin comigratory protein/NADH dehydrogenase/0.453
4h03LARActin, alpha skeletal muscle/0.453
4i0s1B5Tyrosine-protein kinase SYK2.7.10.20.453
4riyADPEpidermal growth factor receptor2.7.10.10.453
5c03AGSNon-receptor tyrosine-protein kinase TYK22.7.10.20.453
1fm4DXCMajor pollen allergen Bet v 1-L/0.452
1m78NDPDihydrofolate reductase1.5.1.30.452
1mf0GDPAdenylosuccinate synthetase isozyme 1/0.452
2bxmIMNSerum albumin/0.452
2isjFMN5,6-dimethylbenzimidazole synthase1.13.11.790.452
2ix5FADAcyl-coenzyme A oxidase 4, peroxisomal1.3.3.60.452
2pd8FADVivid PAS protein VVD/0.452
3bsyACOUDP-N-acetylbacillosamine N-acetyltransferase2.3.1.2030.452
3ef5DGTProbable pyrophosphohydrolase/0.452
3fkqATPNtrC-like two-domain protein/0.452
3pce3HPProtocatechuate 3,4-dioxygenase alpha chain1.13.11.30.452
3pce3HPProtocatechuate 3,4-dioxygenase beta chain1.13.11.30.452
3vcyUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.452
1kfbIGPTryptophan synthase alpha chain/0.451
1nzdUPGDNA beta-glucosyltransferase/0.451
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.451
2dbvNDPGlyceraldehyde-3-phosphate dehydrogenase/0.451
2nv4SAMS-adenosyl-L-methionine-binding protein AF_0241/0.451
2zazGK1Mitogen-activated protein kinase 14/0.451
2zfaFMNLactate oxidase/0.451
3drcMTXDihydrofolate reductase1.5.1.30.451
3gcq1BUMitogen-activated protein kinase 14/0.451
3lf0ATPNitrogen regulatory protein P-II/0.451
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.451
3rj9NADAlcohol dehydrogenase1.1.1.10.451
4boyNADGlyceraldehyde-3-phosphate dehydrogenase/0.451
4eetFMNPhototropin-22.7.11.10.451
4fwfFADLysine-specific histone demethylase 1B10.451
4ho9UTPGlucose-1-phosphate thymidylyltransferase/0.451
4kuoRBFPutative blue-light photoreceptor/0.451
1n6lGTPRas-related protein Rab-5A/0.450
1pjkANPCasein kinase II subunit alpha2.7.11.10.450
1q43CMPPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2/0.450
1rz0FADPhenol 2-hydroxylase component B/0.450
1x31FMNSubunit alpha of sarocosine oxidase/0.450
1x31FMNSubunit beta of sarcosine oxidase/0.450
1xmvADPProtein RecA/0.450
2bxqIMNSerum albumin/0.450
3a4lANPL-seryl-tRNA(Sec) kinase2.7.1.1640.450
3nuyJPZ3-phosphoinositide-dependent protein kinase 12.7.11.10.450
3pcrGTPADP-ribosylation factor 6/0.450
3r9xGNPGTPase Era/0.450
3zh8C58Protein kinase C iota type2.7.11.130.450
4cidANPEH domain-containing protein 2/0.450
4dxd9PCCell division protein FtsZ/0.450
4fuyEK2Mitogen-activated protein kinase 12.7.11.240.450
4loi1YCStimulator of interferon genes protein/0.450
4o1gAGSAdenosine kinase2.7.1.200.450
4yswFADXanthine dehydrogenase/oxidase/0.450
5bylGCPBifunctional AAC/APH2.3.10.450
5cyoGDPSeptin-9/0.450
1g4sTPSThiamine-phosphate synthase/0.449
1os1ATPPhosphoenolpyruvate carboxykinase (ATP)/0.449
1pq944BOxysterols receptor LXR-beta/0.449
1xnjADPBifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 12.7.1.250.449
2dxxSAHDiphthine synthase/0.449
2j9gADPBiotin carboxylase6.3.4.140.449
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.449
2xvw9NRSerum albumin/0.449
2xyuQ9GEphrin type-A receptor 42.7.10.10.449
2ylxFADPhenylacetone monooxygenase1.14.13.920.449
3gbuATPUncharacterized sugar kinase PH14592.7.10.449
3s87ADPRibonucleoside-diphosphate reductase large chain 11.17.4.10.449
3t1tGDPProbable gliding protein mglA/0.449
3tdwGDPGentamicin resistance protein/0.449
4e2bFMNDehydrogenase/0.449
4ikeADPAdenylate kinase/0.449
4in44IDKelch-like ECH-associated protein 1/0.449
4oztP1AEcdysone receptor, putative/0.449
5d3fFSC14-3-3 protein zeta/delta/0.449
1culFOKAdenylate cyclase type 2/0.448
1culFOKAdenylate cyclase type 5/0.448
1h51FMNPentaerythritol tetranitrate reductase/0.448
1t2aNDPGDP-mannose 4,6 dehydratase4.2.1.470.448
1udaUFGUDP-glucose 4-epimerase5.1.3.20.448
2egsSAHDiphthine synthase/0.448
2mwgFMNBlue-light photoreceptor/0.448
2nnkROCProtease/0.448
2rqfJH3Hemolymph juvenile hormone binding protein/0.448
2xj2985Serine/threonine-protein kinase pim-12.7.11.10.448
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.448
3clsFADElectron transfer flavoprotein subunit alpha/0.448
3dj4UD1Bifunctional protein GlmU/0.448
3gg0FMNUncharacterized protein/0.448
3h3fNAIL-lactate dehydrogenase A chain1.1.1.270.448
3hk1B64Fatty acid-binding protein, adipocyte/0.448
3i0aDBHNeutrophil gelatinase-associated lipocalin/0.448
3iahNAPPutative oxoacyl-(Acyl carrier protein) reductase/0.448
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.448
3raiX85Cyclin-dependent kinase 22.7.11.220.448
3sjhLARActin, alpha skeletal muscle/0.448
3upkUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.448
4f1yCNIGlutamate receptor 3/0.448
4xvuATPATPase GET3/0.448
1p4aPCPPur operon repressor/0.447
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
2c27ACOMycothiol acetyltransferase2.3.1.1890.447
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.447
2eudGCQRibonucleoside-diphosphate reductase large chain 11.17.4.10.447
2gmjFADElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial1.5.5.10.447
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.447
2islFNR5,6-dimethylbenzimidazole synthase1.13.11.790.447
2w6nOA2Biotin carboxylase6.3.4.140.447
2wmvZYVSerine/threonine-protein kinase Chk12.7.11.10.447
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.447
3cx6GDPGuanine nucleotide-binding protein subunit alpha-13/0.447
3mjrAC2Deoxycytidine kinase2.7.1.740.447
3mk6ACOPantothenate kinase 32.7.1.330.447
3mpt1GKMitogen-activated protein kinase 14/0.447
3nd1SAHPrecorrin-6A synthase (Deacetylating)/0.447
3sptUD1Bifunctional protein GlmU/0.447
3uqdADPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.447
4fvrATPTyrosine-protein kinase JAK2/0.447
4h0tLARActin, alpha skeletal muscle/0.447
4kuhCAA3-hydroxybutyryl-CoA dehydrogenase/0.447
4rkfGNPRas-related protein Rab-3/0.447
4yswNAIXanthine dehydrogenase/oxidase/0.447
5iqhGNPBifunctional AAC/APH2.3.10.447
1eq2ADQADP-L-glycero-D-manno-heptose-6-epimerase/0.446
1n9nFMNPutative blue light receptor/0.446
1uyhPU0Heat shock protein HSP 90-alpha/0.446
1vcfFMNIsopentenyl-diphosphate delta-isomerase/0.446
1vfrFMNMajor NAD(P)H-flavin oxidoreductase1.6.990.446
1y3aGDPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.446
1y7uCOAAcyl-CoA hydrolase/0.446
1ybaNADD-3-phosphoglycerate dehydrogenase1.1.1.950.446
2vwx7X4Ephrin type-B receptor 42.7.10.10.446
2y3sTIRTamL/0.446
2yvgNADFerredoxin reductase/0.446
3acjKSSTyrosine-protein kinase Lck2.7.10.20.446
3bbfGDPNucleoside diphosphate kinase B2.7.4.60.446
3lsiFADPyranose 2-oxidase/0.446
3nga3NGCasein kinase II subunit alpha2.7.11.10.446
3tw6ADPPyruvate carboxylase/0.446
4bdiHAUSerine/threonine-protein kinase Chk22.7.11.10.446
4cukNAID-lactate dehydrogenase/0.446
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.446
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.446
4ng5NAJAlcohol dehydrogenase E chain1.1.1.10.446
4obuPLPPyridoxal-dependent decarboxylase domain protein/0.446
5e6yACX1,4-alpha-glucan branching enzyme GlgB/0.446
1drhNAPDihydrofolate reductase1.5.1.30.445
1in5ADPHolliday junction ATP-dependent DNA helicase RuvB/0.445
1omoNADAlanine dehydrogenase/0.445
1u3dFADCryptochrome-1/0.445
1v3sATPSignaling protein/0.445
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.445
2eh5SAHDiphthine synthase/0.445
2eleSAHDiphthine synthase/0.445
2q3fGNPRas-related GTP-binding protein D/0.445
2ylzFADPhenylacetone monooxygenase1.14.13.920.445
3ac3KSHTyrosine-protein kinase Lck2.7.10.20.445
3c15GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short/0.445
3fwyADPLight-independent protochlorophyllide reductase iron-sulfur ATP-binding protein/0.445
3m2vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.445
3p0fBAUUridine phosphorylase 22.4.2.30.445
3r5yF42Uncharacterized protein/0.445
3rv9RVDSalicylate synthase/0.445
3v2uATPProtein GAL3/0.445
4bcrWY1Peroxisome proliferator-activated receptor alpha/0.445
4dbvNDPGlyceraldehyde-3-phosphate dehydrogenase/0.445
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.445
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.445
4gt8ADPSensor protein VraS2.7.13.30.445
4h8nNDPNADPH-dependent conjugated polyketone reductase C2/0.445
5ckuNAPL-ornithine N(5)-monooxygenase/0.445
1aylATPPhosphoenolpyruvate carboxykinase (ATP)/0.444
1crbRTLRetinol-binding protein 1/0.444
1diuBDMDihydrofolate reductase1.5.1.30.444
1f17NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.444
1f20NAPNitric oxide synthase, brain1.14.13.390.444
1lqaNDPProtein tas/0.444
2dv5SAHDiphthine synthase/0.444
2gfsPQBMitogen-activated protein kinase 14/0.444
2pckSAHDiphthine synthase/0.444
2rc6NAPFerredoxin--NADP reductase/0.444
2xf04UBSerine/threonine-protein kinase Chk12.7.11.10.444
2xpwOTCTetracycline repressor protein class D/0.444
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.444
2z4y252Geranylgeranyl pyrophosphate synthase/0.444
3cgbCOACoenzyme A disulfide reductase/0.444
3da1FADGlycerol-3-phosphate dehydrogenase/0.444
3p7nFMNLight-activated DNA-binding protein EL222/0.444
3pehIBDEndoplasmin homolog, putative/0.444
3q5lKX2Heat shock protein 83-1/0.444
4eepFMNPhototropin-22.7.11.10.444
4i22IREEpidermal growth factor receptor2.7.10.10.444
4riyANPReceptor tyrosine-protein kinase erbB-32.7.10.10.444
4rww2BALmo2692 protein/0.444
5k2cZMAAdenosine receptor A2a/0.444
1g4pFQPThiamine-phosphate synthase/0.443
1gilGSPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.443
1sbyNADAlcohol dehydrogenase1.1.1.10.443
1vc2NADGlyceraldehyde-3-phosphate dehydrogenase/0.443
1y7lASN_LEU_ASN_ILECysteine synthase2.5.1.470.443
1yjqNAP2-dehydropantoate 2-reductase1.1.1.1690.443
2cduFADNADH oxidase/0.443
2cig1DGDihydrofolate reductase1.5.1.30.443
2dv7SAHDiphthine synthase/0.443
2dxvSAHDiphthine synthase/0.443
2wotZZGTGF-beta receptor type-12.7.11.300.443
2y6o1N1Ephrin type-A receptor 42.7.10.10.443
2zshGA3Gibberellin receptor GID1A30.443
3aosJH2Hemolymph juvenile hormone binding protein/0.443
3bv3P39Mitogen-activated protein kinase 14/0.443
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.443
3e8nVRADual specificity mitogen-activated protein kinase kinase 12.7.12.20.443
3frqERYErythromycin resistance repressor protein/0.443
3iphG11Mitogen-activated protein kinase 14/0.443
3qw4U5POrotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative/0.443
3s79ASDAromatase1.14.14.140.443
3vs2VSBTyrosine-protein kinase HCK2.7.10.20.443
3wv9FEGHmd co-occurring protein HcgE/0.443
4a8v2ANMajor pollen allergen Bet v 1-J/0.443
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.443
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.443
4eiyZMAAdenosine receptor A2a/0.443
4esoNAPPutative oxidoreductase/0.443
4fflADPUncharacterized protein/0.443
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.443
4ftq4HKSerine/threonine-protein kinase Chk12.7.11.10.443
4i1iNADMalate dehydrogenase/0.443
4kcfAKMFAD-dependent oxidoreductase/0.443
4m11MXMProstaglandin G/H synthase 21.14.99.10.443
4qysPLRTryptophan synthase beta chain 24.2.1.200.443
5c3zACPRibokinase/0.443
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.443
5cdsNAJAlcohol dehydrogenase E chain1.1.1.10.443
1c0kFADD-amino-acid oxidase1.4.3.30.442
1ebuNDAHomoserine dehydrogenase1.1.1.30.442
1g0rTHMGlucose-1-phosphate thymidylyltransferase/0.442
1gjrNAPFerredoxin--NADP reductase1.18.1.20.442
1h65GDPTranslocase of chloroplast 343.6.50.442
1i2lDCSAminodeoxychorismate lyase4.1.3.380.442
1mezGDPAdenylosuccinate synthetase isozyme 1/0.442
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.442
1qf4RPDAdenylosuccinate synthetase/0.442
1rkdADPRibokinase/0.442
1rx8NAPDihydrofolate reductase1.5.1.30.442
1s4eADPGalactokinase/0.442
1u7tNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.442
1xddAAYIntegrin alpha-L/0.442
1zky689Estrogen receptor/0.442
2hah3TLPOL protein/0.442
2hog710Serine/threonine-protein kinase Chk12.7.11.10.442
2j9lATPH(+)/Cl(-) exchange transporter 5/0.442
2oxiNADAlcohol dehydrogenase E chain1.1.1.10.442
2vhxNADAlanine dehydrogenase1.4.1.10.442
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.442
2y3pSM8DNA gyrase subunit A/0.442
2yeiXQIHeat shock protein HSP 90-alpha/0.442
3dafFEG5,10-methenyltetrahydromethanopterin hydrogenase1.12.98.20.442
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
3n4mCMPcAMP-activated global transcriptional regulator CRP/0.442
3q5dGDPAtlastin-13.6.50.442
3rgaILDEpoxide hydrolase LasB5.5.10.442
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.442
3w9rA8SAbscisic acid receptor PYL9/0.442
3zkbANPDNA gyrase subunit B/0.442
3zs7ATPPyridoxine/pyridoxal/pyridoxamine kinase/0.442
4jb1FADUDP-N-acetylenolpyruvoylglucosamine reductase/0.442
4r3aRBFBlue-light-activated histidine kinase 22.7.13.30.442
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.442
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
1fcbFMNCytochrome b2, mitochondrial1.1.2.30.441
1hkuNADC-terminal-binding protein 11.1.10.441
1hygNAPL-2-hydroxycarboxylate dehydrogenase (NAD(P)(+))/0.441
1pj2NAINAD-dependent malic enzyme, mitochondrial1.1.1.380.441
1sxjAGSReplication factor C subunit 1/0.441
1uyiPUZHeat shock protein HSP 90-alpha/0.441
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.441
2dsiSAHDiphthine synthase/0.441
2rg6287Mitogen-activated protein kinase 14/0.441
3am3TCLEnoyl-ACP reductase/0.441
3m1vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.441
3m1vCOMMethyl-coenzyme M reductase I subunit beta2.8.4.10.441
3owj1ELCasein kinase II subunit alpha2.7.11.10.441
3pcfFHBProtocatechuate 3,4-dioxygenase beta chain1.13.11.30.441
3swqEPUUDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.441
4ai8DZAHypoxia-inducible factor 1-alpha inhibitor1.14.11.300.441
4b3aTACTetracycline repressor protein class D/0.441
4c717RD3-oxoacyl-ACP synthase/0.441
4dx7DM2Multidrug efflux pump subunit AcrB/0.441
4egnTWOCytochrome P450/0.441
4hxyNDPPlm1/0.441
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.441
4nvk2NYPeroxidase/0.441
4s26SAHPhosphomethylpyrimidine synthase, chloroplastic4.1.99.170.441
5ayzNCNNicotinate-nucleotide pyrophosphorylase [carboxylating]2.4.2.190.441
5iqeGNPBifunctional AAC/APH2.3.10.441
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
1dj3GDPAdenylosuccinate synthetase, chloroplastic/0.440
1dr3TAPDihydrofolate reductase1.5.1.30.440
1icuFMNOxygen-insensitive NAD(P)H nitroreductase/0.440
1k8y13PTryptophan synthase alpha chain/0.440
1qvnFRIInterleukin-2/0.440
1rszDIHPurine nucleoside phosphorylase2.4.2.10.440
1u3vNADAlcohol dehydrogenase 1B1.1.1.10.440
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.440
2dxwSAHDiphthine synthase/0.440
2eudANPRibonucleoside-diphosphate reductase large chain 11.17.4.10.440
2gr0FADFerredoxin reductase/0.440
2ituITQEpidermal growth factor receptor2.7.10.10.440
2ivvPP1Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.440
2rehFADNitroalkane oxidase1.7.3.10.440
2vnmCM8Beta-secretase 13.4.23.460.440
2wo7ASVIsopenicillin N synthase1.21.3.10.440
3c16GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short/0.440
3c6p2S3Protein TRANSPORT INHIBITOR RESPONSE 1/0.440
3clbNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.440
3dmgSAHProbable ribosomal RNA small subunit methyltransferase/0.440
3dt1P40Mitogen-activated protein kinase 14/0.440
3gurBYGGlutathione S-transferase Mu 22.5.1.180.440
3i1fGCPTranslation initiation factor 2 subunit gamma/0.440
3nbvANPKetohexokinase/0.440
3ndcSAHPrecorrin-4 C(11)-methyltransferase2.1.1.1330.440
3pj8404Cyclin-dependent kinase 22.7.11.220.440
3tjzGNPADP-ribosylation factor 1/0.440
3vnhFUUKelch-like ECH-associated protein 1/0.440
4c77N01Phenylacetone monooxygenase1.14.13.920.440
4fsmHK1Serine/threonine-protein kinase Chk12.7.11.10.440
4geb0LDKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.440
4jc51K5Stimulator of interferon genes protein/0.440
4jq7KJQEpidermal growth factor receptor2.7.10.10.440
4q71FADBifunctional protein PutA/0.440
5a0yCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.440
5a0yCOMMethyl-coenzyme M reductase I subunit beta2.8.4.10.440
5dr2ATPAurora kinase A2.7.11.10.440