sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4x24 | TDI | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4x24 | TDI | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | / | 1.000 | |
| 1zos | MTM | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | / | 0.628 | |
| 3eei | MTM | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | / | 0.628 | |
| 1y6q | TDI | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | 3.2.2.9 | 0.607 | |
| 4wkb | TDI | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | / | 0.592 | |
| 1y6r | MTM | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | 3.2.2.9 | 0.591 | |
| 3dp9 | BIG | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | / | 0.583 | |
| 4bmz | MTA | Aminodeoxyfutalosine nucleosidase | / | 0.547 | |
| 1nc1 | MTH | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | 3.2.2.9 | 0.524 | |
| 2bf7 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.519 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.509 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.499 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.499 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.497 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.496 | |
| 1e92 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.492 | |
| 3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.491 | |
| 4ajf | F03 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.491 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.489 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.488 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.487 | |
| 2c94 | TSF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.487 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.487 | |
| 3h4v | DVP | Pteridine reductase 1 | 1.5.1.33 | 0.487 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.486 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.486 | |
| 3ds6 | A17 | Mitogen-activated protein kinase 14 | / | 0.484 | |
| 1mbz | IOT | Carboxyethyl-arginine beta-lactam-synthase | 6.3.3.4 | 0.483 | |
| 2bfp | H4B | Pteridine reductase 1 | 1.5.1.33 | 0.483 | |
| 3ghv | GHC | Dihydrofolate reductase | 1.5.1.3 | 0.483 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.482 | |
| 3sl6 | JN8 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.482 | |
| 4h7z | GUN | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.482 | |
| 4htx | 19F | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.482 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.481 | |
| 2xk3 | XK3 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.481 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.481 | |
| 4kxn | 6K6 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | / | 0.481 | |
| 3d7z | GK5 | Mitogen-activated protein kinase 14 | / | 0.479 | |
| 4az3 | S35 | Lysosomal protective protein | 3.4.16.5 | 0.479 | |
| 4kd7 | 9DR | Dihydrofolate reductase | 1.5.1.3 | 0.479 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.478 | |
| 1trk | TPP | Transketolase 1 | 2.2.1.1 | 0.478 | |
| 2ydv | NEC | Adenosine receptor A2a | / | 0.478 | |
| 3qh2 | 3NM | Thiazole tautomerase | / | 0.478 | |
| 4ajm | 3A6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.478 | |
| 5fuw | THM | Thymidine kinase, putative | / | 0.478 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.477 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.477 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.477 | |
| 1equ | EQI | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.476 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.476 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.476 | |
| 4pah | LNR | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.476 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.475 | |
| 2h94 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.475 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.475 | |
| 3kr6 | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.475 | |
| 4eh8 | IRG | Mitogen-activated protein kinase 14 | / | 0.475 | |
| 7cat | NDP | Catalase | 1.11.1.6 | 0.475 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.474 | |
| 2gvc | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.474 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.474 | |
| 3i1y | 33N | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.474 | |
| 3rix | 923 | Luciferin 4-monooxygenase | 1.13.12.7 | 0.474 | |
| 3tky | N7I | (Iso)eugenol O-methyltransferase | 2.1.1.146 | 0.474 | |
| 1zp4 | C2F | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.473 | |
| 2og8 | 1N8 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.473 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.472 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.472 | |
| 1uae | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.472 | |
| 4dsc | A8S | Abscisic acid receptor PYL3 | / | 0.472 | |
| 4phl | PIL | Phosphodiesterase | / | 0.472 | |
| 1fkw | PUR | Adenosine deaminase | 3.5.4.4 | 0.471 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.471 | |
| 1swt | BTN | Streptavidin | / | 0.471 | |
| 2cy2 | ACO | Probable acetyltransferase | / | 0.471 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.471 | |
| 4hqv | QEI | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.471 | |
| 4pl9 | ADP | Ethylene receptor 1 | / | 0.471 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.470 | |
| 3e92 | G6A | Mitogen-activated protein kinase 14 | / | 0.470 | |
| 3qri | 919 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.470 | |
| 3s41 | S41 | Glucokinase | 2.7.1.2 | 0.470 | |
| 3cwk | REA | Cellular retinoic acid-binding protein 2 | / | 0.469 | |
| 3p2o | NAD | Bifunctional protein FolD | / | 0.469 | |
| 3t5i | SER_SER_CMT_FAR | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.469 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.469 | |
| 5pah | LDP | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.469 | |
| 1eji | THF | Serine hydroxymethyltransferase, cytosolic | / | 0.468 | |
| 1gpu | THD | Transketolase 1 | 2.2.1.1 | 0.468 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.468 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.468 | |
| 2jj2 | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.468 | |
| 2jj2 | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.468 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.468 | |
| 2x2r | ADP | Kinesin-like protein KIF11 | / | 0.468 | |
| 3bi6 | 396 | Wee1-like protein kinase | 2.7.10.2 | 0.468 | |
| 4b1i | A8P | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.468 | |
| 4dhy | S41 | Glucokinase | 2.7.1.2 | 0.468 | |
| 4nbl | 2J6 | Caspase-6 | 3.4.22.59 | 0.468 | |
| 1sd1 | FMC | S-methyl-5'-thioadenosine phosphorylase | / | 0.467 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.467 | |
| 3up3 | XCA | aceDAF-12 | / | 0.467 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.467 | |
| 4guk | P2G | Neuronal calcium sensor 1 | / | 0.467 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.467 | |
| 2ibw | COA | Acetyl-CoA acetyltransferase, mitochondrial | 2.3.1.9 | 0.466 | |
| 2jib | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.466 | |
| 2oh4 | GIG | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.466 | |
| 2ydo | ADN | Adenosine receptor A2a | / | 0.466 | |
| 1fdw | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.465 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.465 | |
| 2fzj | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 2r0p | K2C | Putative FAD-monooxygenase | / | 0.465 | |
| 2xtb | KRM | Adenosine kinase, putative | / | 0.465 | |
| 2yvw | EPU | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.465 | |
| 2zsc | BTN | Tamavidin2 | / | 0.465 | |
| 3hub | 469 | Mitogen-activated protein kinase 14 | / | 0.465 | |
| 4eh2 | IRG | Mitogen-activated protein kinase 14 | / | 0.465 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.465 | |
| 4g8b | HL6 | Alpha/beta hydrolase fold protein | / | 0.465 | |
| 4jv4 | 1OR | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.465 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.465 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.465 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 1lco | PPY | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.464 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 2jc6 | QPP | Calcium/calmodulin-dependent protein kinase type 1D | 2.7.11.17 | 0.464 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.464 | |
| 3ojg | HL4 | Phosphotriesterase | / | 0.464 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.464 | |
| 3wzn | BTN | Streptavidin | / | 0.464 | |
| 4jln | 18V | Deoxycytidine kinase | 2.7.1.74 | 0.464 | |
| 1h36 | R88 | Squalene--hopene cyclase | 4.2.1.129 | 0.463 | |
| 1kce | CB3 | Thymidylate synthase | / | 0.463 | |
| 1wxy | FRK | Adenosine deaminase | 3.5.4.4 | 0.463 | |
| 2wks | CB6 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.463 | |
| 2xkd | T3M | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.463 | |
| 2yix | YIX | Mitogen-activated protein kinase 14 | / | 0.463 | |
| 3ele | PLP | Aminotransferase | / | 0.463 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.463 | |
| 3rin | I2O | Mitogen-activated protein kinase 14 | / | 0.463 | |
| 4d9e | LCS | D-cysteine desulfhydrase | / | 0.463 | |
| 4oma | LCS | Methionine gamma-lyase | / | 0.463 | |
| 1efz | PRF | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.462 | |
| 2cbq | TH2 | Neocarzinostatin | / | 0.462 | |
| 4a4o | 664 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.462 | |
| 4bhw | 01K | Histone acetyltransferase p300 | / | 0.462 | |
| 4dvi | 2IW | Tankyrase-1 | 2.4.2.30 | 0.462 | |
| 4fps | 0UX | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.462 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.462 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1w19 | T1P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.461 | |
| 2c31 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.461 | |
| 2cvz | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.461 | |
| 2xk6 | EQH | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.461 | |
| 3eon | 341 | Glutaryl-CoA dehydrogenase | / | 0.461 | |
| 3qfx | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.461 | |
| 3stu | DK3 | Methylketone synthase I | / | 0.461 | |
| 4b6s | 2HN | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.461 | |
| 4i6f | 1C7 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.461 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.461 | |
| 4pzt | SOP | Histone acetyltransferase p300 | / | 0.461 | |
| 5kf9 | ACO | Predicted acetyltransferase | / | 0.461 | |
| 1mab | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.460 | |
| 1tgv | 5UD | Uridine phosphorylase | 2.4.2.3 | 0.460 | |
| 1xf0 | ASD | Aldo-keto reductase family 1 member C3 | / | 0.460 | |
| 2c42 | TPP | Pyruvate synthase | / | 0.460 | |
| 2pam | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.460 | |
| 2xkf | BX1 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.460 | |
| 3aiq | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic | 3.2.1.182 | 0.460 | |
| 3tub | FPU | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.460 | |
| 3up0 | D7S | aceDAF-12 | / | 0.460 | |
| 3upk | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.460 | |
| 4az0 | S61 | Lysosomal protective protein | 3.4.16.5 | 0.460 | |
| 4dbs | 0HV | Aldo-keto reductase family 1 member C3 | / | 0.460 | |
| 4l5b | 1UX | Deoxycytidine kinase | 2.7.1.74 | 0.460 | |
| 1dis | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 1rzy | 5AS | Histidine triad nucleotide-binding protein 1 | 3 | 0.459 | |
| 1t4v | 14A | Prothrombin | 3.4.21.5 | 0.459 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.459 | |
| 2bfm | TOP | Pteridine reductase 1 | 1.5.1.33 | 0.459 | |
| 2pa7 | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.459 | |
| 2z2w | 770 | Wee1-like protein kinase | 2.7.10.2 | 0.459 | |
| 3hvk | 719 | Catechol O-methyltransferase | 2.1.1.6 | 0.459 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.459 | |
| 4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.459 | |
| 5kf8 | ACO | Predicted acetyltransferase | / | 0.459 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.458 | |
| 2fzd | TOL | Aldose reductase | 1.1.1.21 | 0.458 | |
| 2hzi | JIN | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.458 | |
| 2ovv | PFH | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.458 | |
| 3arv | SAU | Chitinase A | / | 0.458 | |
| 3dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 4ezl | 0SE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.458 | |
| 5g53 | NEC | Adenosine receptor A2a | / | 0.458 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 1nbm | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.457 | |
| 1ryw | EPU | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.457 | |
| 1uml | FR4 | Adenosine deaminase | 3.5.4.4 | 0.457 | |
| 2bxo | OPB | Serum albumin | / | 0.457 | |
| 2jh0 | 701 | Prothrombin | 3.4.21.5 | 0.457 | |
| 2pda | TPP | Pyruvate synthase | / | 0.457 | |
| 2x20 | PID | Peridinin-chlorophyll a-binding protein 1, chloroplastic | / | 0.457 | |
| 3e5a | VX6 | Aurora kinase A | 2.7.11.1 | 0.457 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.457 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.457 | |
| 4dsb | A8S | Abscisic acid receptor PYL3 | / | 0.457 | |
| 5iua | 6DX | Adenosine receptor A2a | / | 0.457 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.456 | |
| 1xls | REA | Retinoic acid receptor RXR-alpha | / | 0.456 | |
| 2ji9 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.456 | |
| 2pak | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.456 | |
| 3caq | NDP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.456 | |
| 4b6u | M7G | Eukaryotic translation initiation factor 4E type 3 | / | 0.456 | |
| 4bcs | BTN | Avidin-related protein 4/5 | / | 0.456 | |
| 4ku5 | DCC | 3-oxoacyl-[ACP] synthase III | / | 0.456 | |
| 4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.456 | |
| 5agy | GTB | Tau class glutathione S-transferase | / | 0.456 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.455 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.455 | |
| 2aqb | TL6 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.455 | |
| 2ij7 | TPF | Mycocyclosin synthase | 1.14.21.9 | 0.455 | |
| 2oci | TYC | Valacyclovir hydrolase | 3.1 | 0.455 | |
| 2xke | WI2 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.455 | |
| 3bsy | ACO | UDP-N-acetylbacillosamine N-acetyltransferase | 2.3.1.203 | 0.455 | |
| 3f0a | ACO | Spermidine N(1)-acetyltransferase | / | 0.455 | |
| 3qp8 | HL0 | Transcriptional activator, LuxR/UhpA family of regulators | / | 0.455 | |
| 3reo | EUG | (Iso)eugenol O-methyltransferase | 2.1.1.146 | 0.455 | |
| 3tvx | PNX | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 3.1.4.53 | 0.455 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.455 | |
| 4d6q | PD2 | Lysine-specific demethylase 4D | 1.14.11 | 0.455 | |
| 4i6h | 1C8 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.455 | |
| 4iwv | 1J9 | Glucokinase | 2.7.1.2 | 0.455 | |
| 4o9c | COA | Acetyl-CoA acetyltransferase | 2.3.1.9 | 0.455 | |
| 4s0v | SUV | Orexin receptor type 2 | / | 0.455 | |
| 1ej3 | CZH | Aequorin-2 | / | 0.454 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.454 | |
| 1ne6 | SP1 | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.454 | |
| 1v08 | NTZ | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic | 3.2.1.182 | 0.454 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.454 | |
| 2vd7 | PD2 | Lysine-specific demethylase 4A | 1.14.11 | 0.454 | |
| 3htj | ET | EbrA repressor | / | 0.454 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.454 | |
| 4biw | ANP | Sensor histidine kinase CpxA | / | 0.454 | |
| 4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.454 | |
| 4fqs | LYA | Thymidylate synthase ThyA | / | 0.454 | |
| 4g1n | NZT | Pyruvate kinase PKM | 2.7.1.40 | 0.454 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.454 | |
| 4ubt | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.454 | |
| 3qak | UKA | Adenosine receptor A2a | / | 0.454 | |
| 1ndy | FR3 | Adenosine deaminase | 3.5.4.4 | 0.453 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.453 | |
| 2flh | ZEA | Cytokinin-specific binding protein | / | 0.453 | |
| 2xk4 | OL2 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.453 | |
| 2yjx | YJX | Heat shock protein HSP 90-alpha | / | 0.453 | |
| 4fev | PP1 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.453 | |
| 4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.453 | |
| 1e7w | MTX | Pteridine reductase 1 | 1.5.1.33 | 0.452 | |
| 1fdt | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.452 | |
| 1fkx | PRH | Adenosine deaminase | 3.5.4.4 | 0.452 | |
| 1h35 | R01 | Squalene--hopene cyclase | 4.2.1.129 | 0.452 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.452 | |
| 1n3s | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.452 | |
| 1nqm | BTN | Streptavidin | / | 0.452 | |
| 1wuu | ANP | Galactokinase | 2.7.1.6 | 0.452 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.452 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.452 | |
| 2q28 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.452 | |
| 2zhw | 12U | Prothrombin | 3.4.21.5 | 0.452 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.452 | |
| 3ndj | JHZ | Methyltransferase | / | 0.452 | |
| 3tl1 | JRO | Putative polyketide cyclase | / | 0.452 | |
| 4pyo | SAH | Catechol O-methyltransferase | 2.1.1.6 | 0.452 | |
| 1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.451 | |
| 1gjr | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.451 | |
| 1lhu | EST | Sex hormone-binding globulin | / | 0.451 | |
| 1p33 | MTX | Pteridine reductase 1 | 1.5.1.33 | 0.451 | |
| 1rd4 | L08 | Integrin alpha-L | / | 0.451 | |
| 1s9d | AFB | Cytohesin-2 | / | 0.451 | |
| 1s9d | AFB | ADP-ribosylation factor 1 | / | 0.451 | |
| 1sri | DMB | Streptavidin | / | 0.451 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.451 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.451 | |
| 2c92 | TP6 | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.451 | |
| 2mm3 | CHO | Gastrotropin | / | 0.451 | |
| 2yki | YKI | Heat shock protein HSP 90-alpha | / | 0.451 | |
| 3bhr | THG | Thymidylate synthase | / | 0.451 | |
| 3dhc | CYK | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.451 | |
| 3dhk | 23U | Prothrombin | 3.4.21.5 | 0.451 | |
| 3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.451 | |
| 3vo2 | FAD | Ferredoxin--NADP reductase | / | 0.451 | |
| 3vwe | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.451 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.451 | |
| 4c2w | ANP | Aurora kinase B-A | 2.7.11.1 | 0.451 | |
| 4hvx | QEI | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.451 | |
| 4jva | 1OR | cAMP-dependent protein kinase type II-beta regulatory subunit | / | 0.451 | |
| 4n1g | CEI | Obelin | / | 0.451 | |
| 4zth | GG5 | Mitogen-activated protein kinase 14 | / | 0.451 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.451 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.450 | |
| 1jwt | BLI | Prothrombin | 3.4.21.5 | 0.450 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.450 | |
| 2fai | 459 | Estrogen receptor | / | 0.450 | |
| 2hp2 | KE4 | Glutamate-1-semialdehyde 2,1-aminomutase | 5.4.3.8 | 0.450 | |
| 2o1x | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.450 | |
| 2vqb | FAD | Putative flavin-containing monooxygenase | / | 0.450 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.450 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.450 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.450 | |
| 3gcq | 1BU | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.450 | |
| 3lfc | Z86 | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 3nwb | 659 | Catechol O-methyltransferase | 2.1.1.6 | 0.450 | |
| 3vo3 | 0KF | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.450 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.450 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.450 | |
| 4eil | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.450 | |
| 4gcx | PRF | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.450 | |
| 4y6n | UPG | Glucosyl-3-phosphoglycerate synthase | 2.4.1.266 | 0.450 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.449 | |
| 1j8u | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.449 | |
| 1jje | BYS | Beta-lactamase | / | 0.449 | |
| 1wnz | 2VA | Isoleucine--tRNA ligase | 6.1.1.5 | 0.449 | |
| 1wp4 | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.449 | |
| 2hq9 | FAD | Mll6688 protein | / | 0.449 | |
| 2obx | INI | 6,7-dimethyl-8-ribityllumazine synthase 2 | 2.5.1.78 | 0.449 | |
| 2rti | GLL | Streptavidin | / | 0.449 | |
| 2wd9 | IBP | Acyl-coenzyme A synthetase ACSM2A, mitochondrial | 6.2.1.2 | 0.449 | |
| 3aiv | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic | 3.2.1.182 | 0.449 | |
| 3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.449 | |
| 3hmv | HBT | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.449 | |
| 3nxy | D2H | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 3ozc | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.449 | |
| 3ppk | FNI | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.449 | |
| 3qpg | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.449 | |
| 3qpp | PFW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.449 | |
| 3sh2 | 5DR | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 3wd9 | QPC | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.449 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.449 | |
| 4ap1 | NAP | Steroid monooxygenase | / | 0.449 | |
| 4er7 | AW3 | Histone-lysine N-methyltransferase, H3 lysine-79 specific | 2.1.1.43 | 0.449 | |
| 4fcd | 0T6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.449 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.449 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.449 | |
| 4kf1 | HT5 | Aryldialkylphosphatase | 3.1.8.1 | 0.449 | |
| 4x7w | MVI | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.449 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1r00 | SAH | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.448 | |
| 1r8q | AFB | Cytohesin-2 | / | 0.448 | |
| 1r8q | AFB | ADP-ribosylation factor 1 | / | 0.448 | |
| 2bif | ANP | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 | 2.7.1.105 | 0.448 | |
| 2c3o | TPP | Pyruvate synthase | / | 0.448 | |
| 2ji7 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.448 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 3thr | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.448 | |
| 3ule | C69 | Actin-related protein 3 | / | 0.448 | |
| 3w5u | FAD | Ferredoxin | / | 0.448 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 4dbc | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.448 | |
| 4epq | 0RR | Poly(ADP-ribose) glycohydrolase | / | 0.448 | |
| 4ixd | 1HV | Integrin alpha-L | / | 0.448 | |
| 4mxe | ACO | N-acetyltransferase ESCO1 | 2.3.1 | 0.448 | |
| 5iu4 | ZMA | Adenosine receptor A2a | / | 0.448 | |
| 1nbu | PH2 | Dihydroneopterin aldolase | / | 0.447 | |
| 1olm | VTQ | SEC14-like protein 2 | / | 0.447 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.447 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.447 | |
| 2w3m | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 3ac1 | KZI | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.447 | |
| 3bx5 | 304 | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 3iej | 599 | Cathepsin S | 3.4.22.27 | 0.447 | |
| 3new | 3NE | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 3qp6 | HL6 | Transcriptional activator, LuxR/UhpA family of regulators | / | 0.447 | |
| 3qpn | PFK | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 3um6 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.447 | |
| 4af7 | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.447 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.447 | |
| 4rqu | NAD | Alcohol dehydrogenase class-P | / | 0.447 | |
| 5ai5 | BSU | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.447 | |
| 1e79 | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.446 | |
| 1e79 | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.446 | |
| 1qxl | FR8 | Adenosine deaminase | 3.5.4.4 | 0.446 | |
| 1typ | NAP | Trypanothione reductase | 1.8.1.12 | 0.446 | |
| 1u1c | BAU | Uridine phosphorylase | 2.4.2.3 | 0.446 | |
| 1xg5 | NAP | Dehydrogenase/reductase SDR family member 11 | / | 0.446 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.446 | |
| 2vmy | FFO | Serine hydroxymethyltransferase | / | 0.446 | |
| 2zb1 | GK4 | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 3ix8 | TX3 | Transcriptional activator protein LasR | / | 0.446 | |
| 3mcy | ZH1 | FimH | / | 0.446 | |
| 3rf7 | NAD | Iron-containing alcohol dehydrogenase | / | 0.446 | |
| 3sso | SAH | Mycinamicin VI 2''-O-methyltransferase | / | 0.446 | |
| 4gts | 7TP | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.446 | |
| 4hfp | 15U | Prothrombin | 3.4.21.5 | 0.446 | |
| 4hne | ADP | Phosphatidylinositol 4-kinase type 2-alpha | / | 0.446 | |
| 4zzj | CNA | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.446 | |
| 1a4l | DCF | Adenosine deaminase | 3.5.4.4 | 0.445 | |
| 1b48 | HAG | Glutathione S-transferase A4 | 2.5.1.18 | 0.445 | |
| 1fcx | 184 | Retinoic acid receptor gamma | / | 0.445 | |
| 1fpq | SAM | Isoliquiritigenin 2'-O-methyltransferase | / | 0.445 | |
| 1kdm | DHT | Sex hormone-binding globulin | / | 0.445 | |
| 1ne4 | RP1 | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.445 | |
| 1o1v | TCH | Gastrotropin | / | 0.445 | |
| 1srf | MTB | Streptavidin | / | 0.445 | |
| 1ybg | TAV | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.445 | |
| 2izh | BTN | Streptavidin | / | 0.445 | |
| 2xvv | 9DN | Serum albumin | / | 0.445 | |
| 2xvw | 9NR | Serum albumin | / | 0.445 | |
| 3hxe | BD8 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.445 | |
| 3ipt | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.445 | |
| 3mb7 | 14I | Casein kinase II subunit alpha | 2.7.11.1 | 0.445 | |
| 3pg3 | DG7 | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 3zc3 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.445 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.445 | |
| 4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.445 | |
| 4m8h | R4M | Retinoic acid receptor RXR-alpha | / | 0.445 | |
| 4y7c | FMN | NADPH--cytochrome P450 reductase | / | 0.445 | |
| 4ykf | NAI | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.445 | |
| 5akk | 1P8 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.445 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.445 | |
| 1e7q | NAP | GDP-L-fucose synthase | / | 0.444 | |
| 1m67 | BOA | Glycerol-3-phosphate dehydrogenase [NAD(+)], glycosomal | 1.1.1.8 | 0.444 | |
| 1ohk | COP | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 2ada | HPR | Adenosine deaminase | 3.5.4.4 | 0.444 | |
| 2g2h | P16 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.444 | |
| 2gou | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.444 | |
| 2nmt | MIM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.444 | |
| 2r9k | SGI | Beta-galactoside-specific lectin 1 | / | 0.444 | |
| 2wqo | VGK | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.444 | |
| 2x7g | PVB | SRSF protein kinase 2 | 2.7.11.1 | 0.444 | |
| 3dh7 | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.444 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.444 | |
| 4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 4eiy | ZMA | Adenosine receptor A2a | / | 0.444 | |
| 4hut | ATP | Cob(I)yrinic acid a,c-diamide adenosyltransferase | 2.5.1.17 | 0.444 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.444 | |
| 4qpz | TPP | Benzaldehyde lyase | / | 0.444 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.444 | |
| 4ykl | GMP | Aprataxin-like protein | 3 | 0.444 | |
| 1bif | AGS | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 | 2.7.1.105 | 0.443 | |
| 1d2s | DHT | Sex hormone-binding globulin | / | 0.443 | |
| 1map | KET | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.443 | |
| 1nce | CB3 | Thymidylate synthase | / | 0.443 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.443 | |
| 1rxh | BNI | Streptavidin | / | 0.443 | |
| 2bfa | CB3 | Pteridine reductase 1 | 1.5.1.33 | 0.443 | |
| 2blb | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 2wba | FAD | Trypanothione reductase | 1.8.1.12 | 0.443 | |
| 2yhu | WHF | Pteridine reductase | / | 0.443 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.443 | |
| 3elm | 24F | Collagenase 3 | 3.4.24 | 0.443 | |
| 3k3i | I46 | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 3kud | GDP | GTPase HRas | / | 0.443 | |
| 3myk | ANP | Myosin-2 heavy chain | / | 0.443 | |
| 3zrr | PXG | Serine-pyruvate aminotransferase (AgxT) | / | 0.443 | |
| 4b5n | FMN | NAD(P)H:flavin oxidoreductase Sye4 | / | 0.443 | |
| 4bj9 | UHB | Tankyrase-2 | 2.4.2.30 | 0.443 | |
| 4dm6 | TTB | Retinoic acid receptor beta | / | 0.443 | |
| 4g67 | SAH | Uncharacterized ACR, COG1565 superfamily | / | 0.443 | |
| 4hvs | 647 | Mast/stem cell growth factor receptor Kit | 2.7.10.1 | 0.443 | |
| 4kak | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 4u0z | APC | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.443 | |
| 5iub | CLR | Adenosine receptor A2a | / | 0.443 | |
| 5jad | FB2 | Platelet-activating factor acetylhydrolase | 3.1.1.47 | 0.443 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.443 | |
| 1bu5 | RBF | Flavodoxin | / | 0.442 | |
| 1cjv | DAD | Adenylate cyclase type 2 | / | 0.442 | |
| 1cjv | DAD | Adenylate cyclase type 5 | / | 0.442 | |
| 1dr4 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1jtq | LY3 | Thymidylate synthase | / | 0.442 | |
| 1oj4 | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.442 | |
| 1q6n | P90 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.442 | |
| 1sre | HAB | Streptavidin | / | 0.442 | |
| 1stp | BTN | Streptavidin | / | 0.442 | |
| 1tka | N3T | Transketolase 1 | 2.2.1.1 | 0.442 | |
| 1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 2aax | PDN | Mineralocorticoid receptor | / | 0.442 | |
| 2in6 | 839 | Wee1-like protein kinase | 2.7.10.2 | 0.442 | |
| 2izf | BTN | Streptavidin | / | 0.442 | |
| 2z7g | EH9 | Adenosine deaminase | 3.5.4.4 | 0.442 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.442 | |
| 3cr0 | 809 | Wee1-like protein kinase | 2.7.10.2 | 0.442 | |
| 3itz | P66 | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 3lq2 | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.442 | |
| 3lth | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.442 | |
| 3mhp | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.442 | |
| 3pah | XDE | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.442 | |
| 3pz2 | 3PZ | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.442 | |
| 4ckr | DI1 | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.442 | |
| 4kzl | 20D | Tankyrase-2 | 2.4.2.30 | 0.442 | |
| 4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.442 | |
| 4qzu | RTL | Retinol-binding protein 2 | / | 0.442 | |
| 1akb | PPD | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.441 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1e8x | ATP | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 1g9c | BAB | Botulinum neurotoxin type B | 3.4.24.69 | 0.441 | |
| 1jom | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1jtu | LYB | Thymidylate synthase | / | 0.441 | |
| 1qrs | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.441 | |
| 1ro6 | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.441 | |
| 1sl9 | CZH | Obelin | / | 0.441 | |
| 1t13 | INI | 6,7-dimethyl-8-ribityllumazine synthase 2 | / | 0.441 | |
| 1t48 | BB3 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.441 | |
| 1tg2 | H2B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.441 | |
| 1w78 | PD8 | Dihydrofolate synthase/folylpolyglutamate synthase | 6.3.2.12 | 0.441 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.441 | |
| 2c9b | PUG | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.441 | |
| 2dw4 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.441 | |
| 2ewa | SB2 | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 2ofv | 242 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.441 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 2r8p | T6F | Transketolase 1 | / | 0.441 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.441 | |
| 2w6q | OA5 | Biotin carboxylase | 6.3.4.14 | 0.441 | |
| 2wwj | Y28 | Lysine-specific demethylase 4A | / | 0.441 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 3mje | NDP | AmphB | / | 0.441 | |
| 3pdq | KC6 | Lysine-specific demethylase 4A | 1.14.11 | 0.441 | |
| 3rg9 | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.441 | |
| 3t4h | MD5 | Alpha-ketoglutarate-dependent dioxygenase AlkB | 1.14.11.33 | 0.441 | |
| 3x2f | NAI | Adenosylhomocysteinase | / | 0.441 | |
| 4ag7 | COA | Glucosamine 6-phosphate N-acetyltransferase | / | 0.441 | |
| 4asj | N6A | Glucose-1-phosphate thymidylyltransferase | / | 0.441 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 4gtv | 7TR | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.441 | |
| 4i5i | 4I5 | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.441 | |
| 4mv4 | ACP | Biotin carboxylase | 6.3.4.14 | 0.441 | |
| 5d7q | AR6 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.441 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.441 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.441 | |
| 1e90 | MYC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 1h42 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.440 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 1ltz | HBI | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.440 | |
| 1nhk | CMP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.440 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 1t4c | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.440 | |
| 1y5x | E89 | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.440 | |
| 2c4c | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.440 | |
| 2d2g | DZZ | Phosphotriesterase | / | 0.440 | |
| 2gcg | NDP | Glyoxylate reductase/hydroxypyruvate reductase | 1.1.1.79 | 0.440 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.440 | |
| 2yat | EEU | Estrogen receptor | / | 0.440 | |
| 3biy | 01K | Histone acetyltransferase p300 | / | 0.440 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3fow | IMH | Purine nucleoside phosphorylase | / | 0.440 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.440 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.440 | |
| 3v4t | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.440 | |
| 4a9e | 3PF | Bromodomain-containing protein 2 | / | 0.440 | |
| 4aoa | IK2 | Beta-phenylalanine transaminase | 2.6.1 | 0.440 | |
| 4eh7 | IRG | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 4eh9 | IRG | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 4g31 | 0WH | Eukaryotic translation initiation factor 2-alpha kinase 3 | 2.7.11.1 | 0.440 | |
| 4hkf | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.440 | |
| 4kbn | 25U | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 4kfj | 1R0 | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 4l4x | NDP | AmphI | / | 0.440 | |
| 4muw | 2F4 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 4nbn | 2J7 | Caspase-6 | 3.4.22.59 | 0.440 | |
| 4was | COO | Enoyl-[acyl-carrier-protein] reductase 1, mitochondrial | 1.3.1.10 | 0.440 | |
| 5dst | SAH | Protein arginine N-methyltransferase 8 | 2.1.1 | 0.440 | |
| 5hbs | RTL | Retinol-binding protein 1 | / | 0.440 | |
| 5il2 | SAH | N6-adenosine-methyltransferase 70 kDa subunit | / | 0.440 |