sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3f47 | I2C | 5,10-methenyltetrahydromethanopterin hydrogenase | 1.12.98.2 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3f47 | I2C | 5,10-methenyltetrahydromethanopterin hydrogenase | 1.12.98.2 | 1.000 | |
| 3f46 | I2C | 5,10-methenyltetrahydromethanopterin hydrogenase | 1.12.98.2 | 0.808 | |
| 3daf | FEG | 5,10-methenyltetrahydromethanopterin hydrogenase | 1.12.98.2 | 0.708 | |
| 3dag | FEG | 5,10-methenyltetrahydromethanopterin hydrogenase | 1.12.98.2 | 0.688 | |
| 3h65 | I2C | 5,10-methenyltetrahydromethanopterin hydrogenase | 1.12.98.2 | 0.677 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.518 | |
| 4gkv | NAD | Alcohol dehydrogenase, propanol-preferring | 1.1.1.1 | 0.511 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.501 | |
| 3ajr | NAD | NDP-sugar epimerase | / | 0.500 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.497 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.497 | |
| 4zir | ANP | Energy-coupling factor transporter ATP-binding protein EcfA2 | 3.6.3 | 0.494 | |
| 4zir | ANP | Energy-coupling factor transporter ATP-binding protein EcfA1 | / | 0.494 | |
| 2wsb | NAD | Galactitol dehydrogenase | / | 0.493 | |
| 4wji | NAP | Putative cyclohexadienyl dehydrogenase and ADH prephenate dehydrogenase | / | 0.488 | |
| 3hdy | FAD | UDP-galactopyranose mutase | / | 0.485 | |
| 3r3s | NAD | Putative oxidoreductase | / | 0.485 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.484 | |
| 3unk | 0BY | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.484 | |
| 4a6b | QG8 | Gag-Pol polyprotein | 3.4.23.16 | 0.484 | |
| 5e8j | SAH | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.484 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.483 | |
| 1di8 | DTQ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.482 | |
| 3iqe | F42 | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.482 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.482 | |
| 1c70 | L75 | Protease | / | 0.481 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.481 | |
| 4k28 | NAD | Shikimate dehydrogenase family protein | / | 0.481 | |
| 4lcg | 1WM | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.480 | |
| 1civ | NAP | Malate dehydrogenase [NADP], chloroplastic | 1.1.1.82 | 0.479 | |
| 2ylr | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.478 | |
| 3iqf | E4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.478 | |
| 3ma3 | 01I | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.478 | |
| 3tz3 | B36 | Acetyl-CoA carboxylase | / | 0.478 | |
| 1ppj | ANY | Cytochrome b | / | 0.477 | |
| 2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.477 | |
| 2npx | NAD | NADH peroxidase | 1.11.1.1 | 0.477 | |
| 2voj | NAD | Alanine dehydrogenase | 1.4.1.1 | 0.477 | |
| 3tea | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.477 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.477 | |
| 1tdu | DUR | Thymidylate synthase | / | 0.476 | |
| 2d8a | NAD | L-threonine 3-dehydrogenase | / | 0.476 | |
| 1v0j | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.475 | |
| 3uhm | RFN | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.475 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.475 | |
| 1fpq | SAM | Isoliquiritigenin 2'-O-methyltransferase | / | 0.474 | |
| 3kyt | HC2 | Nuclear receptor ROR-gamma | / | 0.474 | |
| 1hdz | NAD | Alcohol dehydrogenase 1B | 1.1.1.1 | 0.473 | |
| 3a9w | NAD | NDP-sugar epimerase | / | 0.473 | |
| 4bid | IE8 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.473 | |
| 5lc1 | NAD | L-threonine 3-dehydrogenase | / | 0.473 | |
| 2eph | ASP_TRP_ASN | Fructose-bisphosphate aldolase | 4.1.2.13 | 0.472 | |
| 2znp | K55 | Peroxisome proliferator-activated receptor delta | / | 0.472 | |
| 3iaf | TPP | Benzaldehyde lyase | / | 0.472 | |
| 3t1t | GDP | Probable gliding protein mglA | / | 0.472 | |
| 2fto | CB3 | Thymidylate synthase | / | 0.471 | |
| 2iw9 | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.471 | |
| 3iqz | H4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.471 | |
| 3tqa | NDP | Dihydrofolate reductase | / | 0.471 | |
| 4h4y | NAP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.471 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.470 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 0.470 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.470 | |
| 1fbm | RTL | Cartilage oligomeric matrix protein | / | 0.469 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.469 | |
| 2bpw | 1IN | Gag-Pol polyprotein | 3.4.23.16 | 0.469 | |
| 2qa2 | FAD | Polyketide oxygenase CabE | / | 0.469 | |
| 2vhw | NAI | Alanine dehydrogenase | 1.4.1.1 | 0.469 | |
| 3ict | ADP | Coenzyme A disulfide reductase | / | 0.469 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.469 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.468 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.468 | |
| 2iw8 | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.467 | |
| 3anl | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.467 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.467 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.466 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.466 | |
| 1rek | B8L | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.466 | |
| 2ahr | NAP | Pyrroline-5-carboxylate reductase | / | 0.466 | |
| 2gst | GPS | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.466 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.466 | |
| 3u9e | COA | Lmo1369 protein | / | 0.466 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.466 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.466 | |
| 4qgi | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.466 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.465 | |
| 1tdu | CB3 | Thymidylate synthase | / | 0.465 | |
| 2vhx | NAD | Alanine dehydrogenase | 1.4.1.1 | 0.465 | |
| 3a28 | NAD | L-2,3-butanediol dehydrogenase | 1.1.1.76 | 0.465 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.465 | |
| 3wv7 | ADP | Hmd co-occurring protein HcgE | / | 0.465 | |
| 4m11 | MXM | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.465 | |
| 5bp9 | SAH | Putative methyltransferase protein | / | 0.465 | |
| 5itz | LOC | Tubulin beta-2B chain | / | 0.465 | |
| 1fwk | ADP | Homoserine kinase | 2.7.1.39 | 0.464 | |
| 2fgj | ATP | Alpha-hemolysin translocation ATP-binding protein HlyB | / | 0.464 | |
| 3v9v | 21L | Peroxisome proliferator-activated receptor gamma | / | 0.464 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.464 | |
| 4ez8 | DHF | Thymidylate synthase | 2.1.1.45 | 0.464 | |
| 5emh | NAP | Iridoid synthase | 1.3.1.99 | 0.464 | |
| 5jyd | NAD | Short chain dehydrogenase | / | 0.464 | |
| 2oxi | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.463 | |
| 2yy7 | NAD | L-threonine dehydrogenase | / | 0.463 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.463 | |
| 3tqh | NDP | Quinone oxidoreductase | / | 0.463 | |
| 3ule | C69 | Actin-related protein 3 | / | 0.463 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.463 | |
| 4hjf | C2E | GGDEF family protein | / | 0.463 | |
| 4l42 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.463 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.463 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.462 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.462 | |
| 3a99 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.462 | |
| 4d0l | 093 | Phosphatidylinositol 4-kinase beta | 2.7.1.67 | 0.462 | |
| 4eny | J19 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.462 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.461 | |
| 1iy8 | NAD | Levodione reductase | / | 0.461 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.461 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.461 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.461 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.461 | |
| 3nga | 3NG | Casein kinase II subunit alpha | 2.7.11.1 | 0.461 | |
| 3qtz | X42 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.461 | |
| 3r3b | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.461 | |
| 3ral | 04Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.461 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.461 | |
| 4jaz | STL | Peroxisome proliferator-activated receptor gamma | / | 0.461 | |
| 1chw | HXC | Chalcone synthase 2 | 2.3.1.74 | 0.460 | |
| 1iyz | NDP | Probable quinone oxidoreductase | / | 0.460 | |
| 1nff | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.460 | |
| 1rkx | NAD | CDP-D-glucose-4,6-dehydratase | / | 0.460 | |
| 2ge3 | ACO | Probable acetyltransferase | / | 0.460 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.460 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.460 | |
| 3i59 | N6S | CRP-like cAMP-activated global transcriptional regulator | / | 0.460 | |
| 3ngu | ADP | Nucleoside diphosphate kinase | / | 0.460 | |
| 3nwy | GTP | Uridylate kinase | / | 0.460 | |
| 3pgq | GY3 | Acetyl-CoA carboxylase | / | 0.460 | |
| 3rmf | 20Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.460 | |
| 3wrl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.460 | |
| 4ryv | ZEA | Protein LlR18A | / | 0.460 | |
| 1mgo | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.459 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.459 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.459 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.459 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.459 | |
| 2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 | 0.459 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.459 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 3ggp | NAD | Prephenate dehydrogenase | / | 0.459 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.459 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.459 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.459 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.459 | |
| 4hnc | 0UT | Mandelate racemase | / | 0.459 | |
| 4k2x | FAD | Polyketide oxygenase/hydroxylase | / | 0.459 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.459 | |
| 4yt5 | H4M | H(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ1338 | / | 0.459 | |
| 1tlc | F89 | Thymidylate synthase | / | 0.458 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.458 | |
| 1ydt | IQB | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.458 | |
| 1ykr | 628 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
| 2hqp | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 2udp | UPP | UDP-glucose 4-epimerase | 5.1.3.2 | 0.458 | |
| 2uxu | NAR | HTH-type transcriptional regulator TtgR | / | 0.458 | |
| 2vrb | NAP | Triphenylmethane reductase | / | 0.458 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.458 | |
| 3iqe | H4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.458 | |
| 4l8u | 9AZ | Serum albumin | / | 0.458 | |
| 1ib0 | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.457 | |
| 1o0s | NAI | NAD-dependent malic enzyme, mitochondrial | 1.1.1.38 | 0.457 | |
| 1ppm | 0P1 | Penicillopepsin-1 | 3.4.23.20 | 0.457 | |
| 1rdw | LAR | Actin, alpha skeletal muscle | / | 0.457 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.457 | |
| 2fto | TMP | Thymidylate synthase | / | 0.457 | |
| 2fxe | DR7 | Gag-Pol polyprotein | 3.4.23.16 | 0.457 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.457 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.457 | |
| 2ylx | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.457 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.457 | |
| 3czr | 3CZ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.457 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 3hv5 | R24 | Mitogen-activated protein kinase 14 | / | 0.457 | |
| 3ict | FAD | Coenzyme A disulfide reductase | / | 0.457 | |
| 3img | BZ3 | Pantothenate synthetase | 6.3.2.1 | 0.457 | |
| 3rk7 | 08Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.457 | |
| 3rwp | ABQ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.457 | |
| 3zhq | TPP | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.457 | |
| 4j3d | 1JS | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.457 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.456 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.456 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.456 | |
| 1uum | AFI | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.456 | |
| 2hfu | MEV | Mevalonate kinase | / | 0.456 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.456 | |
| 2ym2 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.456 | |
| 3i59 | N6R | CRP-like cAMP-activated global transcriptional regulator | / | 0.456 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.456 | |
| 3rj5 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.456 | |
| 3unj | 0BX | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 4eu5 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.456 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.456 | |
| 4ft0 | HK9 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.456 | |
| 4fzv | SAM | 5-methylcytosine rRNA methyltransferase NSUN4 | 2.1.1 | 0.456 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.456 | |
| 4xxv | NAD | 3-isopropylmalate dehydrogenase | / | 0.456 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.455 | |
| 1jvs | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.455 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.455 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.455 | |
| 2yy8 | MTA | tRNA (cytidine(56)-2'-O)-methyltransferase | / | 0.455 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.455 | |
| 3r9o | Z71 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
| 4jbo | WPH | Aurora kinase A | 2.7.11.1 | 0.455 | |
| 4kuh | CAA | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.455 | |
| 1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 1npa | 3NH | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 1npw | LGZ | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 1sn5 | T3 | Transthyretin | / | 0.454 | |
| 2a1u | FAD | Electron transfer flavoprotein subunit alpha, mitochondrial | / | 0.454 | |
| 2btr | U73 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.454 | |
| 2p2l | GDP | Ras-related C3 botulinum toxin substrate 1 | / | 0.454 | |
| 2uuv | FAD | Alkyldihydroxyacetonephosphate synthase | 2.5.1.26 | 0.454 | |
| 2uxh | QUE | HTH-type transcriptional regulator TtgR | / | 0.454 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.454 | |
| 2ycf | YCF | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.454 | |
| 3dxm | N24 | Actin-related protein 3 | / | 0.454 | |
| 3fri | SAH | 16S rRNA methylase | / | 0.454 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.454 | |
| 3pt6 | SAH | DNA (cytosine-5)-methyltransferase 1 | 2.1.1.37 | 0.454 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.454 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.454 | |
| 4jlk | 1NO | Deoxycytidine kinase | 2.7.1.74 | 0.454 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.454 | |
| 6gsw | GPS | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.454 | |
| 1nlv | ATP | Major actin | / | 0.453 | |
| 1osv | CHC | Bile acid receptor | / | 0.453 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.453 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.453 | |
| 2wue | KEK | 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase | 3.7.1.17 | 0.453 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 3cxw | 7CP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.453 | |
| 3eql | MXP | DNA-directed RNA polymerase subunit beta | / | 0.453 | |
| 3eql | MXP | DNA-directed RNA polymerase subunit beta' | / | 0.453 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.453 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.453 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.453 | |
| 4afj | SJJ | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.453 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.453 | |
| 4qmp | DKI | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.453 | |
| 1fwm | CB3 | Thymidylate synthase | / | 0.452 | |
| 1i8t | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.452 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.452 | |
| 1mb9 | ATP | Carboxyethyl-arginine beta-lactam-synthase | 6.3.3.4 | 0.452 | |
| 1rj6 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.452 | |
| 1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1udb | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.452 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 2j5x | GSP | ADP-ribosylation factor 6 | / | 0.452 | |
| 2j9l | ATP | H(+)/Cl(-) exchange transporter 5 | / | 0.452 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 3haz | FAD | Bifunctional protein PutA | / | 0.452 | |
| 3i0p | NAD | Malate dehydrogenase, putative | / | 0.452 | |
| 3py0 | SU9 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 3q8u | ADP | Nucleoside diphosphate kinase | / | 0.452 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.452 | |
| 3u33 | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.452 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.452 | |
| 4aic | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.452 | |
| 4dwv | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.452 | |
| 4eub | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.452 | |
| 4jz7 | ANP | Carbamate kinase | / | 0.452 | |
| 4qys | PLR | Tryptophan synthase beta chain 2 | 4.2.1.20 | 0.452 | |
| 4xyb | NDP | Formate dehydrogenase | / | 0.452 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.452 | |
| 5bsf | NAD | Pyrroline-5-carboxylate reductase | / | 0.452 | |
| 5fm7 | ADP | RuvB-like helicase | / | 0.452 | |
| 1j39 | UPG | DNA beta-glucosyltransferase | / | 0.451 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.451 | |
| 2a0c | CK9 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 2cdz | 23D | Serine/threonine-protein kinase PAK 4 | 2.7.11.1 | 0.451 | |
| 2g0n | GDP | Ras-related C3 botulinum toxin substrate 3 | / | 0.451 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.451 | |
| 2p5f | SAH | Diphthine synthase | / | 0.451 | |
| 2pv7 | NAD | T-protein | 1.3.1.12 | 0.451 | |
| 2vhz | NAI | Alanine dehydrogenase | 1.4.1.1 | 0.451 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.451 | |
| 3hll | I45 | Mitogen-activated protein kinase 14 | / | 0.451 | |
| 3sp6 | IL2 | Peroxisome proliferator-activated receptor alpha | / | 0.451 | |
| 3stv | 3HO | Methylketone synthase I | / | 0.451 | |
| 3tiz | 3TI | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 3we4 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.451 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.451 | |
| 4dgn | LU2 | Casein kinase II subunit alpha | 2.7.11.1 | 0.451 | |
| 4fv7 | E94 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.451 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.451 | |
| 4hfm | NAP | 2-alkenal reductase (NADP(+)-dependent) | / | 0.451 | |
| 4xgx | ADP | FAD:protein FMN transferase | / | 0.451 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.451 | |
| 5kjc | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.451 | |
| 1c6x | 3IN | Protease | / | 0.450 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 1f28 | UMP | Thymidylate synthase | 2.1.1.45 | 0.450 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.450 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 1kvt | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.450 | |
| 1oiy | N41 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 1pmn | 984 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.450 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 2fna | ADP | Uncharacterized protein | / | 0.450 | |
| 2h3w | COA | Carnitine O-acetyltransferase | 2.3.1.7 | 0.450 | |
| 2hve | ADP | Nucleoside diphosphate kinase A | 2.7.4.6 | 0.450 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.450 | |
| 3cf0 | ADP | Transitional endoplasmic reticulum ATPase | 3.6.4.6 | 0.450 | |
| 3g70 | A5T | Renin | 3.4.23.15 | 0.450 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.450 | |
| 3oxv | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 3w0p | ADP | Hygromycin-B 4-O-kinase | 2.7.1.163 | 0.450 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 4cpd | NAD | Alcohol dehydrogenase | / | 0.450 | |
| 4jc5 | 1K5 | Stimulator of interferon genes protein | / | 0.450 | |
| 4jvf | 17X | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.450 | |
| 5br7 | FAD | UDP-galactopyranose mutase | / | 0.450 | |
| 5hes | 032 | Mitogen-activated protein kinase kinase kinase 20 | 2.7.11.25 | 0.450 | |
| 1hnc | GDN | Glutathione S-transferase Mu 2 | 2.5.1.18 | 0.449 | |
| 1kgj | FL8 | Transthyretin | / | 0.449 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.449 | |
| 1u28 | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.449 | |
| 1v9a | SAH | Uncharacterized protein | / | 0.449 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.449 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.449 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.449 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 4fic | 0UL | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.449 | |
| 4njv | RIT | Protease | / | 0.449 | |
| 4qmn | DB8 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.449 | |
| 4xx0 | COA | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial | 6.2.1.4 | 0.449 | |
| 5ack | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.449 | |
| 1cbq | RE9 | Cellular retinoic acid-binding protein 2 | / | 0.448 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 1i5b | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.448 | |
| 1mp0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.448 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.448 | |
| 1wn3 | HXC | Phenylacetic acid degradation protein PaaI | / | 0.448 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.448 | |
| 2zb3 | NDP | Prostaglandin reductase 2 | 1.3.1.48 | 0.448 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.448 | |
| 3gds | VAL_TYR_TYR_PHE | Serine endoprotease DegS | 3.4.21.107 | 0.448 | |
| 3kb1 | ADP | Iron-sulfur cluster carrier protein | / | 0.448 | |
| 3kxw | 1ZZ | Saframycin Mx1 synthetase B | / | 0.448 | |
| 3oro | AGS | Serine/threonine protein kinase | / | 0.448 | |
| 3pcr | GTP | ADP-ribosylation factor 6 | / | 0.448 | |
| 3uxy | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.448 | |
| 3w4y | FAD | Mitochondrial FAD-linked sulfhydryl oxidase ERV1 | 1.8.3.2 | 0.448 | |
| 3wfj | NAD | 2-dehydropantoate 2-reductase | / | 0.448 | |
| 4ach | KDI | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.448 | |
| 4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.448 | |
| 4geb | 0LD | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.448 | |
| 4j16 | NAD | NAD/NADP transhydrogenase alpha subunit 1 | / | 0.448 | |
| 4kqw | NAP | Ketol-acid reductoisomerase (NADP(+)) | / | 0.448 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.448 | |
| 4xnh | ACO | N-terminal acetyltransferase A complex subunit NAT5 | 2.3.1 | 0.448 | |
| 5cds | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.448 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1efv | FAD | Electron transfer flavoprotein subunit alpha, mitochondrial | / | 0.447 | |
| 1esv | LAR | Actin, alpha skeletal muscle | / | 0.447 | |
| 1lny | IMO | Adenylosuccinate synthetase isozyme 1 | / | 0.447 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 1r78 | FMD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 2bxm | IMN | Serum albumin | / | 0.447 | |
| 2gqw | FAD | Ferredoxin reductase | / | 0.447 | |
| 2owu | SAH | Diphthine synthase | / | 0.447 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.447 | |
| 2z1m | NDP | GDP-mannose 4,6-dehydratase | / | 0.447 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.447 | |
| 2zui | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 3cgo | JNO | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.447 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 3etd | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.447 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.447 | |
| 3ioc | A5D | Pantothenate synthetase | 6.3.2.1 | 0.447 | |
| 3n7u | NAD | Formate dehydrogenase, chloroplastic/mitochondrial | / | 0.447 | |
| 3nfa | CBJ | Gag-Pol polyprotein | / | 0.447 | |
| 3rpv | 26Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 3sgx | 0FW | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.447 | |
| 3vth | AP2 | Carbamoyltransferase | / | 0.447 | |
| 4dsg | FAD | Uncharacterized protein | / | 0.447 | |
| 4enx | Z20 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.447 | |
| 4fhh | 0U3 | Vitamin D3 receptor A | / | 0.447 | |
| 4h4u | NDP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.447 | |
| 4h4w | NAP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.447 | |
| 4isk | UMP | Thymidylate synthase | / | 0.447 | |
| 4j1r | I5R | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.447 | |
| 4k11 | 0J9 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.447 | |
| 4l0q | NAD | Alcohol dehydrogenase class-3 | / | 0.447 | |
| 4ng5 | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.447 | |
| 4wlo | NAI | Malate dehydrogenase, mitochondrial | 1.1.1.37 | 0.447 | |
| 4xgi | NAD | Glutamate dehydrogenase | / | 0.447 | |
| 4ydu | ADP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.447 | |
| 1c1d | NAI | Phenylalanine dehydrogenase | / | 0.446 | |
| 1ke8 | LS4 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 1s7g | NAD | NAD-dependent protein deacylase 2 | / | 0.446 | |
| 1urw | I1P | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 1wwk | NAD | 307aa long hypothetical phosphoglycerate dehydrogenase | / | 0.446 | |
| 2acw | UPG | Glycosyltransferase | / | 0.446 | |
| 2eka | SAH | Diphthine synthase | / | 0.446 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.446 | |
| 2nmt | NHM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.446 | |
| 2q3k | MUW | Gag-Pol polyprotein | / | 0.446 | |
| 2yj5 | ATP | Copper-transporting ATPase | / | 0.446 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.446 | |
| 3cbs | R12 | Cellular retinoic acid-binding protein 2 | / | 0.446 | |
| 3ggj | 25H | Hypoxanthine-guanine phosphoribosyltransferase | 2.4.2.8 | 0.446 | |
| 3giy | FMN | (S)-mandelate dehydrogenase | 1.1.99.31 | 0.446 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.446 | |
| 3iw1 | ASD | Steroid C26-monooxygenase | 1.14.13.141 | 0.446 | |
| 3l9h | EMQ | Kinesin-like protein KIF11 | / | 0.446 | |
| 3sgt | P09 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | / | 0.446 | |
| 3uwl | FOZ | Thymidylate synthase | / | 0.446 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.446 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.446 | |
| 3zpt | M8Y | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 4a6c | QG9 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 4bkq | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.446 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.446 | |
| 4cql | NAD | Estradiol 17-beta-dehydrogenase 8 | 1.1.1.62 | 0.446 | |
| 4cy8 | FDA | 2-hydroxybiphenyl-3-monooxygenase | / | 0.446 | |
| 4e2b | FMN | Dehydrogenase | / | 0.446 | |
| 4fny | I3K | ALK tyrosine kinase receptor | 2.7.10.1 | 0.446 | |
| 4gyi | ADP | Uncharacterized protein | / | 0.446 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.446 | |
| 4jbq | VX6 | Aurora kinase A | 2.7.11.1 | 0.446 | |
| 4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.446 | |
| 4pgh | SAM | Caffeic acid O-methyltransferase | / | 0.446 | |
| 4r8q | ADP | Mitotic checkpoint serine/threonine-protein kinase BUB1 | 2.7.11.1 | 0.446 | |
| 4rqk | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.446 | |
| 5br4 | NAD | Lactaldehyde reductase | 1.1.1.77 | 0.446 | |
| 3pwh | ZMA | Adenosine receptor A2a | / | 0.446 | |
| 1dhj | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1dyj | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1hld | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.445 | |
| 1m78 | CLZ | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.445 | |
| 1p31 | EPU | UDP-N-acetylmuramate--L-alanine ligase | 6.3.2.8 | 0.445 | |
| 1pag | FMP | Antiviral protein I | 3.2.2.22 | 0.445 | |
| 1qvn | FRI | Interleukin-2 | / | 0.445 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 2dfv | NAD | L-threonine 3-dehydrogenase | / | 0.445 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.445 | |
| 2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.445 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.445 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.445 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.445 | |
| 3bgx | TMP | Thymidylate synthase | / | 0.445 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.445 | |
| 3ggo | NAI | Prephenate dehydrogenase | / | 0.445 | |
| 3gst | GPR | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.445 | |
| 3kyb | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.445 | |
| 3tsc | NAD | Uncharacterized protein | / | 0.445 | |
| 3v9y | 24L | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.445 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 4h4r | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.445 | |
| 4h50 | NAP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.445 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.445 | |
| 4yek | THM | Thymidine phosphorylase | / | 0.445 | |
| 1bdl | IM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 1g4t | FTP | Thiamine-phosphate synthase | / | 0.444 | |
| 1gij | 2PU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.444 | |
| 1nq7 | ARL | Nuclear receptor ROR-beta | / | 0.444 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 1o8c | NDP | Probable acrylyl-CoA reductase AcuI | 1.3.1.84 | 0.444 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.444 | |
| 1tj1 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.444 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.444 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.444 | |
| 2fzw | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.444 | |
| 2j7p | GNP | Signal recognition particle protein | / | 0.444 | |
| 2j7p | GNP | Signal recognition particle receptor FtsY | / | 0.444 | |
| 2jam | J60 | Calcium/calmodulin-dependent protein kinase type 1G | 2.7.11.17 | 0.444 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.444 | |
| 2ohx | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.444 | |
| 2pwu | GUN | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.444 | |
| 2q61 | SF1 | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 2rf2 | MRX | Gag-Pol polyprotein | 2.7.7.49 | 0.444 | |
| 2vhv | NAI | Alanine dehydrogenase | 1.4.1.1 | 0.444 | |
| 2wed | PP6 | Penicillopepsin-1 | 3.4.23.20 | 0.444 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 3ad9 | NAD | Subunit alpha of sarocosine oxidase | / | 0.444 | |
| 3clb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.444 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.444 | |
| 3mfs | ANP | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.444 | |
| 3rpy | 27Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.444 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.444 | |
| 4fgg | 0U5 | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 4g6g | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.444 | |
| 4kig | ENO | Phenylpyruvate C(3)-methyltransferase | 2.1.1.281 | 0.444 | |
| 4lb2 | DM5 | Serum albumin | / | 0.444 | |
| 4nc3 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.444 | |
| 4wa9 | AXI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.444 | |
| 4wuo | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.444 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.444 | |
| 1iid | NHM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.443 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.443 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.443 | |
| 1tz8 | DES | Transthyretin | / | 0.443 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.443 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.443 | |
| 1wyg | FAD | Xanthine dehydrogenase/oxidase | / | 0.443 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.443 | |
| 1zdw | FLV | Prenyltransferase | / | 0.443 | |
| 2ev9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.443 | |
| 2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.443 | |
| 2qd5 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.443 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.443 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.443 | |
| 2ylz | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.443 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 3fow | IMH | Purine nucleoside phosphorylase | / | 0.443 | |
| 3icr | COA | Coenzyme A disulfide reductase | / | 0.443 | |
| 3inv | C50 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 3lfq | A28 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 3ncg | BK1 | Calmodulin-domain protein kinase 1, putative | / | 0.443 | |
| 3pgh | FLP | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.443 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.443 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.443 | |
| 4b7s | QLE | Cytochrome P450 monooxygenase PikC | / | 0.443 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.443 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.443 | |
| 4g47 | TZF | Mycocyclosin synthase | 1.14.21.9 | 0.443 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.443 | |
| 4iq7 | 1G9 | Mycocyclosin synthase | 1.14.21.9 | 0.443 | |
| 4kl9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 4lch | 1WN | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.443 | |
| 4qpm | ADP | Mitotic checkpoint serine/threonine-protein kinase BUB1 | 2.7.11.1 | 0.443 | |
| 4rpg | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.443 | |
| 4ytn | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.443 | |
| 5f8e | SAH | Possible transcriptional regulatory protein | / | 0.443 | |
| 1b15 | NAE | Alcohol dehydrogenase | 1.1.1.1 | 0.442 | |
| 1bvg | DMP | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 1bwf | ATF | Glycerol kinase | / | 0.442 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 1eio | GCH | Gastrotropin | / | 0.442 | |
| 1hsz | NAD | Alcohol dehydrogenase 1B | 1.1.1.1 | 0.442 | |
| 1n4h | REA | Nuclear receptor ROR-beta | / | 0.442 | |
| 1oi9 | N20 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 1rx5 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1wuu | ANP | Galactokinase | 2.7.1.6 | 0.442 | |
| 2gew | FAD | Cholesterol oxidase | 1.1.3.6 | 0.442 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.442 | |
| 2od7 | A1R | NAD-dependent protein deacetylase HST2 | 3.5.1 | 0.442 | |
| 2ozu | ACO | Histone acetyltransferase KAT6A | / | 0.442 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.442 | |
| 2vxo | XMP | GMP synthase [glutamine-hydrolyzing] | 6.3.5.2 | 0.442 | |
| 3bqd | DAY | Glucocorticoid receptor | / | 0.442 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.442 | |
| 3r3f | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.442 | |
| 3vsp | EK8 | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 3w33 | W19 | Epidermal growth factor receptor | 2.7.10.1 | 0.442 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.442 | |
| 4d03 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.442 | |
| 4da8 | BG2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.442 | |
| 4e5n | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.442 | |
| 4iah | 1DX | Alr2278 protein | / | 0.442 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.442 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.442 | |
| 4wlv | NAD | Malate dehydrogenase, mitochondrial | 1.1.1.37 | 0.442 | |
| 4ykf | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.442 | |
| 4z69 | DIF | Serum albumin | / | 0.442 | |
| 1c6z | ROC | Protease | / | 0.441 | |
| 1ke6 | LS2 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 1kqo | DND | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.441 | |
| 1p91 | SAM | 23S rRNA (guanine(745)-N(1))-methyltransferase | / | 0.441 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 1u2g | APR | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.441 | |
| 1v59 | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.441 | |
| 1x8v | ESL | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.441 | |
| 1xef | ATP | Alpha-hemolysin translocation ATP-binding protein HlyB | / | 0.441 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.441 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.441 | |
| 2exc | JNK | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.441 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.441 | |
| 2gmv | PEP | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | 4.1.1.32 | 0.441 | |
| 2itp | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.441 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.441 | |
| 2j3k | NAP | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.441 | |
| 3a7r | LAQ | Lipoate-protein ligase A | 6.3.1.20 | 0.441 | |
| 3ac3 | KSH | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.441 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.441 | |
| 3flw | FLW | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.441 | |
| 3il1 | B5D | Glutamate receptor 2 | / | 0.441 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.441 | |
| 3nbv | ANP | Ketohexokinase | / | 0.441 | |
| 3opd | HIE | Heat shock protein 83 | / | 0.441 | |
| 3uku | C69 | Actin-related protein 3 | / | 0.441 | |
| 3vey | 0H5 | Glucokinase | 2.7.1.2 | 0.441 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.441 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.441 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.441 | |
| 4acg | 6LQ | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.441 | |
| 4c2y | MYA | Glycylpeptide N-tetradecanoyltransferase 1 | / | 0.441 | |
| 4c4g | 7RO | Dual specificity protein kinase TTK | 2.7.12.1 | 0.441 | |
| 4dlb | NAD | S-(hydroxymethyl)glutathione dehydrogenase | / | 0.441 | |
| 4ehy | ADP | Tetraacyldisaccharide 4'-kinase | / | 0.441 | |
| 4el5 | D1M | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.441 | |
| 4g73 | NAI | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.441 | |
| 4hfr | 14M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 4kz0 | 1UJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 4oj4 | DIF | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.441 | |
| 4u9a | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.441 | |
| 4x7u | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.441 | |
| 4x9n | FAD | Uncharacterized protein MG039 homolog | / | 0.441 | |
| 4xey | 1N1 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.441 | |
| 5a3c | NAD | SIR2 family protein | / | 0.441 | |
| 5bsg | NAP | Pyrroline-5-carboxylate reductase | / | 0.441 | |
| 5dn3 | ATP | Aurora kinase A | 2.7.11.1 | 0.441 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.441 | |
| 1k3l | GTX | Glutathione S-transferase A1 | 2.5.1.18 | 0.440 | |
| 1ke9 | LS5 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 1rd4 | L08 | Integrin alpha-L | / | 0.440 | |
| 1tys | TMP | Thymidylate synthase | / | 0.440 | |
| 1vza | UMP | Thymidylate synthase | / | 0.440 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.440 | |
| 1yt9 | OIS | Gag-Pol polyprotein | / | 0.440 | |
| 2bx8 | AZQ | Serum albumin | / | 0.440 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.440 | |
| 2cvj | FAD | Thioredoxin reductase related protein | / | 0.440 | |
| 2egs | SAH | Diphthine synthase | / | 0.440 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.440 | |
| 2hqm | FAD | Glutathione reductase | 1.8.1.7 | 0.440 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 2qfx | NDP | Isocitrate dehydrogenase [NADP], mitochondrial | 1.1.1.42 | 0.440 | |
| 3aid | ARQ | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 3bhe | BZN | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 3fpz | AHZ | Thiamine thiazole synthase | / | 0.440 | |
| 3g72 | A6T | Renin | 3.4.23.15 | 0.440 | |
| 3rk9 | 09Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 4a33 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.440 | |
| 4aw0 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 | |
| 4b1b | FAD | Thioredoxin reductase | 1.8.1.9 | 0.440 | |
| 4da6 | GA2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.440 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.440 | |
| 4ez7 | 2AN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 4l04 | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.440 | |
| 4l4f | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 4qe6 | JN3 | Bile acid receptor | / | 0.440 | |
| 4yzc | STU | Serine/threonine-protein kinase/endoribonuclease IRE1 | 2.7.11.1 | 0.440 | |
| 5eyp | LOC | Tubulin beta chain | / | 0.440 | |
| 5ify | UMP | Glucose-1-phosphate thymidylyltransferase | / | 0.440 |