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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3a62STURibosomal protein S6 kinase beta-12.7.11.1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3a62STURibosomal protein S6 kinase beta-12.7.11.11.000
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.604
2hog710Serine/threonine-protein kinase Chk12.7.11.10.580
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.580
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.564
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.563
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.559
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.558
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.557
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.556
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.556
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.555
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.554
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.553
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.552
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.551
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.548
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.547
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.547
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.545
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.545
4ftq4HKSerine/threonine-protein kinase Chk12.7.11.10.542
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.542
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.541
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.541
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.541
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.539
1wvxBD4Death-associated protein kinase 12.7.11.10.538
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.538
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.538
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.537
4fsmHK1Serine/threonine-protein kinase Chk12.7.11.10.536
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.535
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.535
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.535
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.535
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.534
2wmrZYRSerine/threonine-protein kinase Chk12.7.11.10.533
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.533
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.532
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.531
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.531
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.531
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.531
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.530
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.529
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.529
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.529
2pe039Z3-phosphoinositide-dependent protein kinase 12.7.11.10.528
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.528
4fsyHK7Serine/threonine-protein kinase Chk12.7.11.10.528
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.527
3qd03Q43-phosphoinositide-dependent protein kinase 12.7.11.10.526
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.524
4ftjH8KSerine/threonine-protein kinase Chk12.7.11.10.524
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.524
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.523
4bdfH3RSerine/threonine-protein kinase Chk22.7.11.10.522
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.521
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.521
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.521
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.521
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.520
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.520
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.519
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.518
3t8oATPRhodopsin kinase/0.518
4bdiHAUSerine/threonine-protein kinase Chk22.7.11.10.518
2qhn582Serine/threonine-protein kinase Chk12.7.11.10.517
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.516
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.516
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.516
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.515
1ny3ADPMAP kinase-activated protein kinase 22.7.11.10.514
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.514
1zrzBI1Protein kinase C iota type2.7.11.130.514
3qd33Q53-phosphoinositide-dependent protein kinase 12.7.11.10.514
4yhjAN2G protein-coupled receptor kinase 42.7.11.160.514
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.513
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.512
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.512
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.511
3we45FIRibosomal protein S6 kinase beta-12.7.11.10.511
4ftaH5KSerine/threonine-protein kinase Chk12.7.11.10.511
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.511
3nuuJOZ3-phosphoinositide-dependent protein kinase 12.7.11.10.510
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.510
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.509
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.509
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.509
3amaSKEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.509
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.509
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.509
2wtiWTISerine/threonine-protein kinase Chk22.7.11.10.508
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.508
3sheI85MAP kinase-activated protein kinase 32.7.11.10.508
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.508
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.508
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.507
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.507
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.507
3zh8C58Protein kinase C iota type2.7.11.130.507
4bdgP3JSerine/threonine-protein kinase Chk22.7.11.10.507
4wboANWRhodopsin kinase/0.507
4jik1KOSerine/threonine-protein kinase Chk12.7.11.10.506
4bcmT7ZCyclin-dependent kinase 22.7.11.220.505
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.505
1q5kTMUGlycogen synthase kinase-3 beta2.7.11.260.504
2wmtZYTSerine/threonine-protein kinase Chk12.7.11.10.504
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.504
4bdhWVISerine/threonine-protein kinase Chk22.7.11.10.504
2ckeIQUDeath-associated protein kinase 2/0.503
5auwQUEDeath-associated protein kinase 12.7.11.10.503
3gubGUBDeath-associated protein kinase 12.7.11.10.502
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.502
3nuyJPZ3-phosphoinositide-dependent protein kinase 12.7.11.10.502
4fob0USALK tyrosine kinase receptor2.7.10.10.502
4ftn2HKSerine/threonine-protein kinase Chk12.7.11.10.502
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.502
2ym3YM3Serine/threonine-protein kinase Chk12.7.11.10.501
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.501
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.500
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.500
3kn5ANPRibosomal protein S6 kinase alpha-52.7.11.10.500
3krwBA1Beta-adrenergic receptor kinase 12.7.11.150.499
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.499
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.498
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.498
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.497
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.497
4ft3H1KSerine/threonine-protein kinase Chk12.7.11.10.497
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.497
2j0m4STFocal adhesion kinase 12.7.10.20.496
3igoANPCalmodulin-domain protein kinase 1, putative/0.496
4c62XWWTyrosine-protein kinase JAK2/0.496
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.496
4ct2ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.496
5av4GENDeath-associated protein kinase 12.7.11.10.496
3c4xATPRhodopsin kinase/0.495
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.494
3bqr4RBDeath-associated protein kinase 3/0.494
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.494
3v8t477Tyrosine-protein kinase ITK/TSK2.7.10.20.494
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.494
1uv5BRWGlycogen synthase kinase-3 beta2.7.11.260.493
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.493
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.493
3eb0DRKUncharacterized protein/0.493
4hvh19RTyrosine-protein kinase JAK32.7.10.20.493
4rqvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.493
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.492
2wmsZYSSerine/threonine-protein kinase Chk12.7.11.10.492
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.492
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.492
4b99R4LMitogen-activated protein kinase 72.7.11.240.492
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.492
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.492
5auvAGIDeath-associated protein kinase 12.7.11.10.492
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.491
4fg9ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.491
1g5sI17Cyclin-dependent kinase 22.7.11.220.490
2vd5BI8Myotonin-protein kinase2.7.11.10.489
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.489
2wxvWXVCyclin-dependent kinase 22.7.11.220.488
3bhy7CPDeath-associated protein kinase 3/0.488
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.488
5av2KMPDeath-associated protein kinase 12.7.11.10.488
5dr9SKEAurora kinase A2.7.11.10.488
1fvv107Cyclin-dependent kinase 22.7.11.220.487
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.487
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.487
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.487
3gu6ADPDeath-associated protein kinase 12.7.11.10.487
4fv6E57Mitogen-activated protein kinase 12.7.11.240.487
2wmvZYVSerine/threonine-protein kinase Chk12.7.11.10.486
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.486
4cd0AWJALK tyrosine kinase receptor2.7.10.10.486
4fto3HKSerine/threonine-protein kinase Chk12.7.11.10.486
4gk2L66Ephrin type-A receptor 32.7.10.10.486
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.485
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.485
2ydjYDJSerine/threonine-protein kinase Chk12.7.11.10.485
3nlb5BESerine/threonine-protein kinase Chk12.7.11.10.485
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.485
4hvg19QTyrosine-protein kinase JAK32.7.10.20.485
1q3wATUGlycogen synthase kinase-3 beta2.7.11.260.484
1z5mLI83-phosphoinositide-dependent protein kinase 12.7.11.10.484
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.484
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.484
4fv1EK4Mitogen-activated protein kinase 12.7.11.240.484
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.484
4yuqKS1Calmodulin-like domain protein kinase/0.484
1xjdSTUProtein kinase C theta type2.7.11.130.483
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.483
3ezrEZRCyclin-dependent kinase 22.7.11.220.483
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.483
4fv9E71Mitogen-activated protein kinase 12.7.11.240.483
5auxKMPDeath-associated protein kinase 12.7.11.10.483
1nxkSTUMAP kinase-activated protein kinase 22.7.11.10.482
1zys199Serine/threonine-protein kinase Chk12.7.11.10.482
3lltANPProtein serine/threonine kinase-1/0.482
3pvwQRXBeta-adrenergic receptor kinase 12.7.11.150.482
3zewSTUEphrin type-B receptor 42.7.10.10.482
4fstHK4Serine/threonine-protein kinase Chk12.7.11.10.482
1uu3LY43-phosphoinositide-dependent protein kinase 12.7.11.10.481
2x6dX6DAurora kinase A2.7.11.10.481
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.481
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.480
3wi6YRZMAP kinase-activated protein kinase 22.7.11.10.480
4k8aK8AFocal adhesion kinase 12.7.10.20.480
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.479
2x1nX1NCyclin-dependent kinase 22.7.11.220.479
2xf04UBSerine/threonine-protein kinase Chk12.7.11.10.479
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.479
2yexYEXSerine/threonine-protein kinase Chk12.7.11.10.479
4erkOLOMitogen-activated protein kinase 12.7.11.240.479
4eutBX7Serine/threonine-protein kinase TBK12.7.11.10.479
4l3l5FIRibosomal protein S6 kinase beta-12.7.11.10.479
4qnaX11Serine/threonine-protein kinase 242.7.11.10.479
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.479
5aaaVGHALK tyrosine kinase receptor2.7.10.10.479
2ijmADPFocal adhesion kinase 12.7.10.20.478
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.478
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.478
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.478
1q8uH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.477
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.477
1wvySTUDeath-associated protein kinase 12.7.11.10.477
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.477
4foc0UUALK tyrosine kinase receptor2.7.10.10.477
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.477
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.476
3nynSGVG protein-coupled receptor kinase 62.7.11.160.476
3qcx3Q23-phosphoinositide-dependent protein kinase 12.7.11.10.476
4bddZ0OSerine/threonine-protein kinase Chk22.7.11.10.476
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.476
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.476
2vv9IM9Cyclin-dependent kinase 22.7.11.220.475
2xb7GUIALK tyrosine kinase receptor2.7.10.10.475
3cjgKIMVascular endothelial growth factor receptor 22.7.10.10.475
3tnwF18Cyclin-dependent kinase 22.7.11.220.475
2wmxZY6Serine/threonine-protein kinase Chk12.7.11.10.474
3i60E86Mitogen-activated protein kinase 12.7.11.240.474
1pkdUCNCyclin-dependent kinase 22.7.11.220.473
1u54ACPActivated CDC42 kinase 1/0.473
1uu8BI13-phosphoinositide-dependent protein kinase 12.7.11.10.473
2acxANPG protein-coupled receptor kinase 62.7.11.160.473
2in6839Wee1-like protein kinase2.7.10.20.473
3eyhIZATyrosine-protein kinase JAK1/0.473
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.473
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.473
4c61LMMTyrosine-protein kinase JAK2/0.473
1eh4IC1Casein kinase I homolog 12.7.11.10.472
1m2rMNYCasein kinase II subunit alpha2.7.11.10.472
1uu7BI23-phosphoinositide-dependent protein kinase 12.7.11.10.472
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.472
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.472
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.472
2j0lANPFocal adhesion kinase 12.7.10.20.472
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.472
2yn8STUEphrin type-B receptor 42.7.10.10.472
3s2pPMUCyclin-dependent kinase 22.7.11.220.472
4bgh3I6Cyclin-dependent kinase 22.7.11.220.472
4f640S8Fibroblast growth factor receptor 1/0.472
4ftlH0KSerine/threonine-protein kinase Chk12.7.11.10.472
4o0sADNAurora kinase A2.7.11.10.472
1rekB8LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.471
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.471
2ydkYDKSerine/threonine-protein kinase Chk12.7.11.10.471
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.471
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.471
4o0wADNAurora kinase A2.7.11.10.471
1h1r6CPCyclin-dependent kinase 22.7.11.220.470
1yvj4STTyrosine-protein kinase JAK32.7.10.20.470
2i40BLZCyclin-dependent kinase 22.7.11.220.470
2ojj82AMitogen-activated protein kinase 12.7.11.240.470
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.470
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.470
3oogYTPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.470
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.470
4dk50KOPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.470
4jajXU1Aurora kinase A2.7.11.10.470
5dt0SKEAurora kinase A2.7.11.10.470
1ke6LS2Cyclin-dependent kinase 22.7.11.220.469
2izuP01Casein kinase I isoform gamma-32.7.11.10.469
2pwlACPFibroblast growth factor receptor 2/0.469
3dfcANPDeath-associated protein kinase 12.7.11.10.469
3lcdBDYMacrophage colony-stimulating factor 1 receptor2.7.10.10.469
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.469
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.469
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.469
5e8xSTUTGF-beta receptor type-12.7.11.300.469
1oiyN41Cyclin-dependent kinase 22.7.11.220.468
2ycfYCFSerine/threonine-protein kinase Chk22.7.11.10.468
3sqq99ZCyclin-dependent kinase 22.7.11.220.468
4fx360KCyclin-dependent kinase 22.7.11.220.468
4hvi19STyrosine-protein kinase JAK32.7.10.20.468
1e9hINRCyclin-dependent kinase 22.7.11.220.467
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.467
2x9fX9FEphrin type-B receptor 42.7.10.10.467
2yaaATPDeath-associated protein kinase 2/0.467
2yac937Serine/threonine-protein kinase PLK12.7.11.210.467
3orzBI43-phosphoinositide-dependent protein kinase 12.7.11.10.467
4mf129YTyrosine-protein kinase ITK/TSK2.7.10.20.467
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.467
1gih1PUCyclin-dependent kinase 22.7.11.220.466
4bcqTJFCyclin-dependent kinase 22.7.11.220.466
2itpAEEEpidermal growth factor receptor2.7.10.10.465
3qc9ADPRhodopsin kinase/0.465
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.465
5aacVGHALK tyrosine kinase receptor2.7.10.10.465
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.464
2bkzSBCCyclin-dependent kinase 22.7.11.220.464
2etm7PYFocal adhesion kinase 12.7.10.20.464
2ym8YM8Serine/threonine-protein kinase Chk12.7.11.10.464
3mfrANPPeripheral plasma membrane protein CASK2.7.11.10.464
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.464
1ke5LS1Cyclin-dependent kinase 22.7.11.220.463
2c5nCK8Cyclin-dependent kinase 22.7.11.220.463
2uzvSS5cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.463
2xngA0HAurora kinase A2.7.11.10.463
4dgo0JWCasein kinase II subunit alpha2.7.11.10.463
4fod0UVALK tyrosine kinase receptor2.7.10.10.463
4gii0X6Non-receptor tyrosine-protein kinase TYK22.7.10.20.463
4jia1K3Tyrosine-protein kinase JAK2/0.463
4ks7X4ZSerine/threonine-protein kinase PAK 62.7.11.10.463
4l9i8PRRhodopsin kinase/0.463
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.462
1phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.462
2btrU73Cyclin-dependent kinase 22.7.11.220.462
2f7e2EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.462
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.462
2xikJ60Serine/threonine-protein kinase 252.7.11.10.462
4acdGR9Glycogen synthase kinase-3 beta2.7.11.260.462
4bdbODOSerine/threonine-protein kinase Chk22.7.11.10.462
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.462
4im2BX7Serine/threonine-protein kinase TBK12.7.11.10.462
4ivc1J6Tyrosine-protein kinase JAK1/0.462
2biyATP3-phosphoinositide-dependent protein kinase 12.7.11.10.461
2cn8DBQSerine/threonine-protein kinase Chk22.7.11.10.461
3e8eG98cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.461
3ral04ZCyclin-dependent kinase 22.7.11.220.461
3vetADPnebramycin 5' synthase6.1.2.20.461
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
4jbqVX6Aurora kinase A2.7.11.10.461
2p2h994Vascular endothelial growth factor receptor 22.7.10.10.460
3s4qNK0Mitogen-activated protein kinase 14/0.460
4a4l939Serine/threonine-protein kinase PLK12.7.11.210.460
4ic7ANPMitogen-activated protein kinase 72.7.11.240.460
4jqeANPCasein kinase II subunit alpha2.7.11.10.460
4l445FIRibosomal protein S6 kinase beta-12.7.11.10.460
4ysjADPCalmodulin-like domain protein kinase/0.460
5aabVGHALK tyrosine kinase receptor2.7.10.10.460
5av3KMPDeath-associated protein kinase 12.7.11.10.460
1oguST8Cyclin-dependent kinase 22.7.11.220.459
1snuSTUTyrosine-protein kinase ITK/TSK2.7.10.20.459
2vgoAD5Aurora kinase B-A2.7.11.10.459
4erwSTUCyclin-dependent kinase 22.7.11.220.459
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.459
4gk3L87Ephrin type-A receptor 32.7.10.10.459
2w1fL0FAurora kinase A2.7.11.10.458
3a8wATPProtein kinase C iota type2.7.11.130.458
3h3cP1EProtein-tyrosine kinase 2-beta2.7.10.20.458
3kc3MK2MAP kinase-activated protein kinase 22.7.11.10.458
3m42HGFMAP kinase-activated protein kinase 22.7.11.10.458
4brxKGWFocal adhesion kinase 12.7.10.20.458
4i22IREEpidermal growth factor receptor2.7.10.10.458
5auzGENDeath-associated protein kinase 12.7.11.10.458
2c4g514Cyclin-dependent kinase 22.7.11.220.457
2itqITQEpidermal growth factor receptor2.7.10.10.457
2j0k4STFocal adhesion kinase 12.7.10.20.457
2wmwZYWSerine/threonine-protein kinase Chk12.7.11.10.457
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.457
3vf9477Tyrosine-protein kinase SYK2.7.10.20.457
4b8lA0PAurora kinase B-A2.7.11.10.457
4wkqIREEpidermal growth factor receptor2.7.10.10.457
1dq8COA3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.340.456
1p4fDRGDeath-associated protein kinase 12.7.11.10.456
2cmwOLPCasein kinase I isoform gamma-12.7.11.10.456
2uw0GVKcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.456
3bhh5CPCalcium/calmodulin-dependent protein kinase type II subunit beta2.7.11.170.456
3pvuQRWBeta-adrenergic receptor kinase 12.7.11.150.456
3rkb12ZCyclin-dependent kinase 22.7.11.220.456
3rvg17PTyrosine-protein kinase JAK2/0.456
3zep1NXTyrosine-protein kinase JAK32.7.10.20.456
4f1sF1SPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
4mf029ZTyrosine-protein kinase ITK/TSK2.7.10.20.456
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.456
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.456
2cchATPCyclin-dependent kinase 22.7.11.220.455
2gu8796cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.455
2j9mPY8Cyclin-dependent kinase 22.7.11.220.455
2xneASHAurora kinase A2.7.11.10.455
2xp2VGHALK tyrosine kinase receptor2.7.10.10.455
4enyJ19Serine/threonine-protein kinase pim-12.7.11.10.455
4ix6ADPUncharacterized protein/0.455
4j97ACPFibroblast growth factor receptor 2/0.455
4jboWPHAurora kinase A2.7.11.10.455
2j7t274Serine/threonine-protein kinase 102.7.11.10.454
2vu3LZECyclin-dependent kinase 22.7.11.220.454
2wipP49Cyclin-dependent kinase 22.7.11.220.454
3lctADPALK tyrosine kinase receptor2.7.10.10.454
3q92XNBKetohexokinase/0.454
3vjoANPEpidermal growth factor receptor2.7.10.10.454
1pxmCK5Cyclin-dependent kinase 22.7.11.220.453
1q8tY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.453
1w0xOLOCyclin-dependent kinase 22.7.11.220.453
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
2gdo12CSerine/threonine-protein kinase Chk12.7.11.10.453
3c4zADPRhodopsin kinase/0.453
3gb2G3BGlycogen synthase kinase-3 beta2.7.11.260.453
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.453
4gmy0X5Tyrosine-protein kinase JAK2/0.453
5dr6SKEAurora kinase A2.7.11.10.453
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
3c50ADPRhodopsin kinase/0.452
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.452
3pxkPXKFocal adhesion kinase 12.7.10.20.452
4deeADPAurora kinase A2.7.11.10.452
4ez50RSCyclin-dependent kinase 62.7.11.220.452
4fuxE75Mitogen-activated protein kinase 12.7.11.240.452
2btsU32Cyclin-dependent kinase 22.7.11.220.451
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
2eufLQQCyclin-dependent kinase 62.7.11.220.451
2uzeC95Cyclin-dependent kinase 22.7.11.220.451
2x2lX2LProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.451
2xa4AZ5Tyrosine-protein kinase JAK2/0.451
2yfxVGHALK tyrosine kinase receptor2.7.10.10.451
3ag9A02cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.451
3f7z34OGlycogen synthase kinase-3 beta2.7.11.260.451
4afjSJJGlycogen synthase kinase-3 beta2.7.11.260.451
4dgnLU2Casein kinase II subunit alpha2.7.11.10.451
4ekl0RFRAC-alpha serine/threonine-protein kinase2.7.11.10.451
4jhz1KVBeta-glucuronidase3.2.1.310.451
4qgiROCGag-Pol polyprotein3.4.23.160.451
5dpvSKEAurora kinase A2.7.11.10.451
5drdATPAurora kinase A2.7.11.10.451
1finATPCyclin-dependent kinase 22.7.11.220.450
1oecAA2Fibroblast growth factor receptor 2/0.450
1xl2189Gag-Pol polyprotein3.4.23.160.450
2h96893Mitogen-activated protein kinase 82.7.11.240.450
2pvnP63Casein kinase II subunit alpha2.7.11.10.450
2qo9ANPEphrin type-A receptor 32.7.10.10.450
2uzlC94Cyclin-dependent kinase 22.7.11.220.450
2w06FRVCyclin-dependent kinase 22.7.11.220.450
3jy0LYGSerine/threonine-protein kinase pim-12.7.11.10.450
3k5uPFQAurora kinase A2.7.11.10.450
3q3b55EGlycogen synthase kinase-3 beta2.7.11.260.450
4anmWULCasein kinase II subunit alpha2.7.11.10.450
4ccbOFGALK tyrosine kinase receptor2.7.10.10.450
4mvfSTUCalcium-dependent protein kinase 22.7.11.10.450
4wsqKSAAP2-associated protein kinase 12.7.11.10.450
2izt23DCasein kinase I isoform gamma-32.7.11.10.449
2jkqVG8Focal adhesion kinase 12.7.10.20.449
2y7jB49Phosphorylase b kinase gamma catalytic chain, liver/testis isoform2.7.11.190.449
3c4wATPRhodopsin kinase/0.449
3emg685Tyrosine-protein kinase SYK2.7.10.20.449
3rni21ZCyclin-dependent kinase 22.7.11.220.449
4nks2M2Fibroblast growth factor receptor 1/0.449
2dwbANPAurora kinase A2.7.11.10.448
2e9p77ASerine/threonine-protein kinase Chk12.7.11.10.448
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.448
2iw84SPCyclin-dependent kinase 22.7.11.220.448
2j0j4STFocal adhesion kinase 12.7.10.20.448
2r64740Cyclin-dependent kinase 22.7.11.220.448
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.448
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.448
2yerTQ1Serine/threonine-protein kinase Chk12.7.11.10.448
3cy3JN5Serine/threonine-protein kinase pim-12.7.11.10.448
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.448
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.448
4c02TAKActivin receptor type-12.7.11.300.448
4ezj0SCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
4l435FIRibosomal protein S6 kinase beta-12.7.11.10.448
1mruAGSSerine/threonine-protein kinase PknB2.7.11.10.447
1unlRRCCyclin-dependent-like kinase 52.7.11.10.447
1vjy460TGF-beta receptor type-12.7.11.300.447
1vyzN5BCyclin-dependent kinase 22.7.11.220.447
2vrx447Aurora kinase B-A2.7.11.10.447
3ddpRC8Cyclin-dependent kinase 22.7.11.220.447
3pe2E1BCasein kinase II subunit alpha2.7.11.10.447
4e93GUITyrosine-protein kinase Fes/Fps2.7.10.20.447
4ek610KCyclin-dependent kinase 22.7.11.220.447
4f650S9Fibroblast growth factor receptor 1/0.447
4fjyFJYPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.446
1ke9LS5Cyclin-dependent kinase 22.7.11.220.446
1ppm0P1Penicillopepsin-13.4.23.200.446
1xr1ANPSerine/threonine-protein kinase pim-12.7.11.10.446
2xru400Aurora kinase A2.7.11.10.446
3bu5ATPInsulin receptor2.7.10.10.446
3dpd41APhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
3nux3NVCyclin-dependent kinase 62.7.11.220.446
4fkpLS5Cyclin-dependent kinase 22.7.11.220.446
4fv2EK5Mitogen-activated protein kinase 12.7.11.240.446
4gk4L90Ephrin type-A receptor 32.7.10.10.446
5dt3ATPAurora kinase A2.7.11.10.446
1bxoPP7Penicillopepsin-13.4.23.200.445
1oitHDTCyclin-dependent kinase 22.7.11.220.445
1v1k3FPCyclin-dependent kinase 22.7.11.220.445
2bfyH1NAurora kinase B-A2.7.11.10.445
2uztSS3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
3dndLL2cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
3et7349Protein-tyrosine kinase 2-beta2.7.10.20.445
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.445
3hx4ANPCalmodulin-domain protein kinase 1/0.445
3iok1P6Tyrosine-protein kinase JAK2/0.445
3nc9TR3Ketohexokinase/0.445
3rk507ZCyclin-dependent kinase 22.7.11.220.445
3ztxZTXAurora kinase B-A2.7.11.10.445
4fkv61KCyclin-dependent kinase 22.7.11.220.445
4i0r1B4Tyrosine-protein kinase SYK2.7.10.20.445
4j1rI5RGlycogen synthase kinase-3 beta2.7.11.260.445
4y93746Tyrosine-protein kinase/0.445
5e8ySTUTGF-beta receptor type-22.7.11.300.445
1oi9N20Cyclin-dependent kinase 22.7.11.220.444
2uzbC75Cyclin-dependent kinase 22.7.11.220.444
3hztJ60Calmodulin-like domain protein kinase isoform 3/0.444
3qlg1N1Proto-oncogene tyrosine-protein kinase Src2.7.10.20.444
3w33W19Epidermal growth factor receptor2.7.10.10.444
3zvvXAZPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.444
4anqVGHALK tyrosine kinase receptor2.7.10.10.444
4c58824Cyclin-G-associated kinase2.7.11.10.444
4dtaADNAPH(2'')-Id/0.444
4gu94GUFocal adhesion kinase 12.7.10.20.444
4i4e1BQFocal adhesion kinase 12.7.10.20.444
5auuLU2Death-associated protein kinase 12.7.11.10.444
1py5PY1TGF-beta receptor type-12.7.11.300.443
1yolS03Proto-oncogene tyrosine-protein kinase Src2.7.10.20.443
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.443
2xszATPRuvB-like 23.6.4.120.443
2yiqYIQSerine/threonine-protein kinase Chk22.7.11.10.443
3umw596Serine/threonine-protein kinase pim-12.7.11.10.443
3v5j0F2Tyrosine-protein kinase ITK/TSK2.7.10.20.443
3zrkZRKGlycogen synthase kinase-3 beta2.7.11.260.443
4a4o664Serine/threonine-protein kinase PLK12.7.11.210.443
4anwO92Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4fad0TBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4hvb19PPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.443
4qmpDKISerine/threonine-protein kinase 242.7.11.10.443
5dosATPAurora kinase A2.7.11.10.443
1q8wM77cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.442
2itnANPEpidermal growth factor receptor2.7.10.10.442
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.442
2w17I19Cyclin-dependent kinase 22.7.11.220.442
3ml9ML9Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
3my5RFZCyclin-dependent kinase 22.7.11.220.442
3r8lZ30Cyclin-dependent kinase 22.7.11.220.442
3raiX85Cyclin-dependent kinase 22.7.11.220.442
4aacAAVMitogen-activated protein kinase 14/0.442
4eor4SPCyclin-dependent kinase 22.7.11.220.442
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.442
2ittAEEEpidermal growth factor receptor2.7.10.10.441
2owb626Serine/threonine-protein kinase PLK12.7.11.210.441
2wtjWTJSerine/threonine-protein kinase Chk22.7.11.10.441
3d7tSTUTyrosine-protein kinase CSK/0.441
3lfqA28Cyclin-dependent kinase 22.7.11.220.441
3uo50BXAurora kinase A2.7.11.10.441
4a9uA9USerine/threonine-protein kinase Chk22.7.11.10.441
4bdaVFBSerine/threonine-protein kinase Chk22.7.11.10.441
4fkt48KCyclin-dependent kinase 22.7.11.220.441
4fmqANPMitogen-activated protein kinase 12.7.11.240.441
4fnzNZFALK tyrosine kinase receptor2.7.10.10.441
4ivd15TTyrosine-protein kinase JAK1/0.441
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.441
5dt4ATPAurora kinase A2.7.11.10.441
1meiXMPInosine-5'-monophosphate dehydrogenase/0.440
2w1gL0GAurora kinase A2.7.11.10.440
3qaiXNNKetohexokinase/0.440
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.440
4dgmAGICasein kinase II subunit alpha2.7.11.10.440
4ek816KCyclin-dependent kinase 22.7.11.220.440
4g170VNCasein kinase I isoform gamma-32.7.11.10.440
4grb0XGCasein kinase II subunit alpha2.7.11.10.440
4qmySTUSerine/threonine-protein kinase 242.7.11.10.440