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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1j8qFMNFlavodoxin

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
1j8qFMNFlavodoxin/1.000
2fx2FMNFlavodoxin/0.646
1fx1FMNFlavodoxin/0.636
1wsbFMNFlavodoxin/0.629
1akwFMNFlavodoxin/0.605
1azlFMNFlavodoxin/0.604
1akuFMNFlavodoxin/0.603
5fx2FMNFlavodoxin/0.593
1j9gFMNFlavodoxin/0.583
1akrFMNFlavodoxin/0.576
5tgzFMNCannabinoid receptor 1/0.552
4fx2FMNFlavodoxin/0.547
3f6sFMNFlavodoxin/0.546
1xyvFMNFlavodoxin/0.538
3nytULPUDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase2.6.1.980.530
4y7cFMNNADPH--cytochrome P450 reductase/0.529
3f6rFMNFlavodoxin/0.525
5xraFMNCannabinoid receptor 1/0.525
3kaqFMNFlavodoxin/0.524
3kapFMNFlavodoxin/0.515
4oxxFMNCindoxin/0.508
1ahnFMNFlavodoxin 1/0.507
1c7fFMNFlavodoxin/0.507
4bfzZVZPantothenate kinase2.7.1.330.496
3f90FMNFlavodoxin/0.494
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.492
4xnw2IDP2Y purinoceptor 1/0.492
2mokFMNFlavodoxin 1/0.491
1bu5RBFFlavodoxin/0.489
2pzjNADPutative nucleotide sugar epimerase/ dehydratase/0.487
1rsgFADPolyamine oxidase FMS1/0.486
1ykgFMNSulfite reductase [NADPH] flavoprotein alpha-component/0.486
4r81FMNPredicted NADH dehydrogenase/0.486
1cznFMNFlavodoxin/0.483
2ejzSAHDiphthine synthase/0.483
2gbyBRNHTH-type transcriptional regulator QacR/0.483
3ojxFMNNADPH--cytochrome P450 reductase/0.483
3w2fNADNADH-cytochrome b5 reductase 31.6.2.20.483
4jtqNAPAldo-keto reductase family 1 member C2/0.483
1kyxCRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.482
1xyyFMNFlavodoxin/0.482
2fcrFMNFlavodoxin/0.481
3sn6P0GBeta-2 adrenergic receptor/0.480
1votHUPAcetylcholinesterase3.1.1.70.479
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.479
3sqzCOAPutative hydroxymethylglutaryl-CoA synthase/0.479
4bj9UHBTankyrase-22.4.2.300.479
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.479
3esyFMNFlavodoxin/0.478
4b4vL34Bifunctional protein FolD/0.478
5xr8FMNCannabinoid receptor 1/0.478
1pq944BOxysterols receptor LXR-beta/0.477
3e34ED1Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.477
3e34ED1Protein farnesyltransferase subunit beta2.5.1.580.477
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.477
2r8pT6FTransketolase 1/0.476
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.476
4bb3KKAIsopenicillin N synthase1.21.3.10.476
2j3qTFLAcetylcholinesterase3.1.1.70.475
3dopNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.475
3h3qH13Collagen type IV alpha-3-binding protein/0.475
4x9dU5PUncharacterized protein MJ1435/0.475
2v5uFMNFlavodoxin/0.474
3mauPLRPutative sphingosine-1-phosphate lyase/0.474
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.474
4twnB96Ephrin type-A receptor 32.7.10.10.474
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.474
1q84TZ4Acetylcholinesterase3.1.1.70.473
3c3xNAPEugenol synthase 11.1.1.3180.473
3fpkFADFerredoxin-NADP reductase/0.473
3kjgADPCO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC/0.473
4a959MTGlycylpeptide N-tetradecanoyltransferase/0.473
1gpuTHDTransketolase 12.2.1.10.472
2ii6C5PAlpha-2,3/2,6-sialyltransferase/sialidase/0.472
2nmtMIMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.472
3ggs2FDPurine nucleoside phosphorylase2.4.2.10.472
3pftFMNFlavin reductase/0.472
4b1hAR6Poly(ADP-ribose) glycohydrolase3.2.1.1430.472
2a2cADPN-acetylgalactosamine kinase2.7.1.1570.471
2cekN8TAcetylcholinesterase3.1.1.70.471
4bfvZVVPantothenate kinase2.7.1.330.471
4epq0RRPoly(ADP-ribose) glycohydrolase/0.471
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.471
4bfxZVXPantothenate kinase2.7.1.330.470
1icpFMN12-oxophytodienoate reductase 11.3.1.420.469
1w6rGNTAcetylcholinesterase3.1.1.70.469
1zsbAZMCarbonic anhydrase 24.2.1.10.469
2a58RBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.469
2hpvFMNFMN-dependent NADH-azoreductase1.70.469
3ae4N1MSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial1.3.5.10.469
3ae4N1MSuccinate dehydrogenase cytochrome b560 subunit, mitochondrial/0.469
3hr4FMNNitric oxide synthase, inducible1.14.13.390.469
4b63NAPL-ornithine N(5)-monooxygenase/0.469
1j9zFADNADPH--cytochrome P450 reductase/0.468
4e2dFMNDehydrogenase/0.468
4rh10TTSpore photoproduct lyase/0.468
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.467
1i7pFADNADH-cytochrome b5 reductase 31.6.2.20.467
1kw8BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.467
2c9zQUEAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.467
2wwjY28Lysine-specific demethylase 4A/0.467
3biy01KHistone acetyltransferase p300/0.467
3fhxPLPPyridoxal kinase2.7.1.350.467
3gfbNADL-threonine 3-dehydrogenase/0.467
3v2uATPProtein GAL3/0.467
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.466
2x06NADL-sulfolactate dehydrogenase/0.466
3dvaTPWPyruvate dehydrogenase E1 component subunit alpha1.2.4.10.466
3dvaTPWPyruvate dehydrogenase E1 component subunit beta1.2.4.10.466
3e23SAMUncharacterized protein/0.466
4a322CDGlycylpeptide N-tetradecanoyltransferase/0.466
1j9zFMNNADPH--cytochrome P450 reductase/0.465
1ofvFMNFlavodoxin/0.465
2c20NADUDP-glucose 4-epimerase/0.465
2r8oT5XTransketolase 1/0.465
2wu4HBPAcetylcholinesterase3.1.1.70.465
2xuhTZ4Acetylcholinesterase3.1.1.70.465
3exfTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.465
3exfTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.465
3i6qNDPPutative leucoanthocyanidin reductase 1/0.465
3imxB84Glucokinase2.7.1.20.465
4drjRAPSerine/threonine-protein kinase mTOR2.7.11.10.465
4drjRAPPeptidyl-prolyl cis-trans isomerase FKBP45.2.1.80.465
4hfr14MCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.465
4relKMPGlycosyltransferase/0.465
4z0pNDPNAD-dependent dehydrogenase/0.465
1q5mNDPProstaglandin-E(2) 9-reductase1.1.1.1890.464
1tl7ONMAdenylate cyclase type 2/0.464
1tl7ONMAdenylate cyclase type 5/0.464
1uxyEPUUDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.464
1vgqCAOFormyl-CoA:oxalate CoA-transferase/0.464
3gncQQQGlutaryl-CoA dehydrogenase/0.464
1gpnHUBAcetylcholinesterase3.1.1.70.463
2a2dANPN-acetylgalactosamine kinase2.7.1.1570.463
2q7oIMHPurine nucleoside phosphorylase2.4.2.10.463
3h3r14HCollagen type IV alpha-3-binding protein/0.463
4bmpFMNProtein NrdI/0.463
4eqsCOACoenzyme A disulfide reductase/0.463
4n82FMNRibonucleotide reductase (NrdI family protein), putative/0.463
1icqOPD12-oxophytodienoate reductase 11.3.1.420.462
1ulbGUNPurine nucleoside phosphorylase2.4.2.10.462
1yciNDFHypoxia-inducible factor 1-alpha inhibitor1.14.11.300.462
2pncCLUPrimary amine oxidase, liver isozyme/0.462
1e66HUXAcetylcholinesterase3.1.1.70.461
1h42FADFerredoxin--NADP reductase1.18.1.20.461
1w19T5P6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.461
1yqzCOACoenzyme A disulfide reductase/0.461
2b5oFADFerredoxin--NADP reductase1.18.1.20.461
2clmF6FTryptophan synthase alpha chain/0.461
3jyoNADQuinate/shikimate dehydrogenase (NAD(+))/0.461
3zj7C1KStrictosidine-O-beta-D-glucosidase3.2.1.1050.461
4gz612VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.461
4zqcF6FTryptophan synthase alpha chain/0.461
1rkwPNTHTH-type transcriptional regulator QacR/0.460
1zgbA1EAcetylcholinesterase3.1.1.70.460
2qimZEAClass 10 plant pathogenesis-related protein/0.460
2rdn1PL1-deoxypentalenic acid 11-beta-hydroxylase1.14.11.350.460
2xugTZ4Acetylcholinesterase3.1.1.70.460
3c1kT15Prothrombin3.4.21.50.460
3ivcFG4Pantothenate synthetase6.3.2.10.460
3q7fED2Uncharacterized protein/0.460
3uylTYDProbable NDP-rhamnosyltransferase/0.460
4eu9COASuccinyl-CoA:acetate CoA-transferase/0.460
4imfSI3N-acetylneuraminate lyase/0.460
4mr72BVGamma-aminobutyric acid type B receptor subunit 1/0.460
1g63FMNEpidermin decarboxylase4.1.10.459
1gky5GPGuanylate kinase2.7.4.80.459
1h22E10Acetylcholinesterase3.1.1.70.459
1mxfMTXPutative pteridine reductase 2/0.459
2dshSAHDiphthine synthase/0.459
3ai0PNWBeta-glucosidase/0.459
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.459
3dzkNMNADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.459
4eywL0RCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.459
1hb1OCVIsopenicillin N synthase1.21.3.10.458
1icsFMN12-oxophytodienoate reductase 11.3.1.420.458
1ix1BB2Peptide deformylase/0.458
1qtiGNTAcetylcholinesterase3.1.1.70.458
2iviACWIsopenicillin N synthase1.21.3.10.458
2o3uNGDADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.458
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.458
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.458
4mlp2CXCryptochrome-2/0.458
4u140HKMuscarinic acetylcholine receptor M3/0.458
1ndhFADNADH-cytochrome b5 reductase 31.6.2.20.457
1odcA8BAcetylcholinesterase3.1.1.70.457
1rt9IMHPurine nucleoside phosphorylase2.4.2.10.457
1z6tADPApoptotic protease-activating factor 1/0.457
2bb3SAHCobalamin biosynthesis precorrin-6Y methylase (CbiE)/0.457
2bu9HFVIsopenicillin N synthase1.21.3.10.457
2ed3SAHDiphthine synthase/0.457
2h3wHC5Carnitine O-acetyltransferase2.3.1.70.457
2v2zCDM4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.457
3klbFMNUncharacterized protein/0.457
3nz2ACOHexapeptide-repeat containing-acetyltransferase/0.457
4tvj09LPoly [ADP-ribose] polymerase 22.4.2.300.457
5dp2NAPCurF/0.457
1xf0ASDAldo-keto reductase family 1 member C3/0.456
2aouCQAHistamine N-methyltransferase2.1.1.80.456
2ffqGSPRas-related protein Rab-6B/0.456
2ok8FADFerredoxin--NADP reductase, apicoplast/0.456
2y60M8FIsopenicillin N synthase1.21.3.10.456
3jypNADQuinate/shikimate dehydrogenase (NAD(+))/0.456
3k4s0MOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.456
3u57DH8Raucaffricine-O-beta-D-glucosidase3.2.1.1250.456
3zoiM2WIsopenicillin N synthase1.21.3.10.456
4bcaFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.456
4briUNPEctonucleoside triphosphate diphosphohydrolase I/0.456
5c1d12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.456
1cjkFOKAdenylate cyclase type 2/0.455
1cjkFOKAdenylate cyclase type 5/0.455
1dx6GNTAcetylcholinesterase3.1.1.70.455
1rzuADPGlycogen synthase 12.4.1.210.455
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.455
2r5nTPPTransketolase 1/0.455
2vbpVB1Isopenicillin N synthase1.21.3.10.455
2xjeU5PCytosolic purine 5'-nucleotidase3.1.3.50.455
3bxoUPPdTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose/0.455
3ddw055Glycogen phosphorylase, liver form2.4.1.10.455
3mhpFADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.455
4gv7MEWPoly [ADP-ribose] polymerase 12.4.2.300.455
4hb9FADUncharacterized protein/0.455
4nv10FXFormyl transferase/0.455
4q0kGA3Phytohormone-binding protein/0.455
1a9cGTPGTP cyclohydrolase 13.5.4.160.454
1fdrFADFerredoxin--NADP reductase1.18.1.20.454
2c12FADNitroalkane oxidase1.7.3.10.454
2vq7NAPPutative flavin-containing monooxygenase/0.454
2xukTZ5Acetylcholinesterase3.1.1.70.454
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.454
3sqxANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.454
3zv7NHGAcetylcholinesterase3.1.1.70.454
1svlADPLarge T antigen3.6.40.453
1tllFMNNitric oxide synthase, brain1.14.13.390.453
1vbiNADMalate/L-lactate dehydrogenase family protein/0.453
2cmfF11Acetylcholinesterase3.1.1.70.453
2vd7PD2Lysine-specific demethylase 4A1.14.110.453
2xuiTZ5Acetylcholinesterase3.1.1.70.453
3bi6396Wee1-like protein kinase2.7.10.20.453
3jqrFADFerredoxin--NADP reductase, apicoplast/0.453
3junAJDPhenazine biosynthesis protein A/B/0.453
3ksqZ96Protein farnesyltransferase subunit beta2.5.1.580.453
4af7FADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.453
4gi5FADPutative NAD(P)H dehydrogenase (Quinone)/0.453
4y17LAETranscriptional regulator of ftsQAZ gene cluster/0.453
4yfy1YJVioF/0.453
5stdUNNScytalone dehydratase4.2.1.940.453
1nhkCMPNucleoside diphosphate kinase2.7.4.60.452
1ygjRMCPyridoxal kinase2.7.1.350.452
2bt4CA23-dehydroquinate dehydratase4.2.1.100.452
2poqISDTrans-1,2-dihydrobenzene-1,2-diol dehydrogenase1.3.1.200.452
3dzjNMNADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.452
3fr5I4AFatty acid-binding protein, adipocyte/0.452
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.452
3ou2SAHSAM-dependent methyltransferase/0.452
3ukfGDUUDP-galactopyranose mutase/0.452
3zc3FADFerredoxin--NADP reductase1.18.1.20.452
4araC56Acetylcholinesterase3.1.1.70.452
4arbC57Acetylcholinesterase3.1.1.70.452
4b65NDPL-ornithine N(5)-monooxygenase/0.452
4m0cFMNFMN-dependent NADH-azoreductase 1/0.452
1if8SBSCarbonic anhydrase 24.2.1.10.451
1jnrFADAdenylylsulfate reductase, subunit A (AprA)/0.451
1pwyAC2Purine nucleoside phosphorylase2.4.2.10.451
1u71MXADihydrofolate reductase1.5.1.30.451
2ha6SCKAcetylcholinesterase3.1.1.70.451
3copADPGlycogen synthase2.4.1.210.451
3p0fBAUUridine phosphorylase 22.4.2.30.451
3slkNDPPolyketide synthase extender module 2/0.451
3voiRCBGlucanase/0.451
4b1iA8PPoly(ADP-ribose) glycohydrolase3.2.1.1430.451
4br0AU1Ectonucleoside triphosphate diphosphohydrolase 2/0.451
4fapARDPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.451
4fapARDSerine/threonine-protein kinase mTOR2.7.11.10.451
4ms1381Gamma-aminobutyric acid type B receptor subunit 1/0.451
1d0lBLGMembrane-bound lytic murein transglycosylase B4.2.2.n10.450
1h69ARHNAD(P)H dehydrogenase [quinone] 11.6.5.20.450
1paxDHQPoly [ADP-ribose] polymerase 12.4.2.300.450
1tj0FADBifunctional protein PutA1.5.5.20.450
2aclL05Oxysterols receptor LXR-alpha/0.450
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.450
2xuoTZ4Acetylcholinesterase3.1.1.70.450
2xvhFADPutative flavin-containing monooxygenase/0.450
3f8sPF2Dipeptidyl peptidase 4/0.450
3ojxFADNADPH--cytochrome P450 reductase/0.450
3qi4IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.450
3to3ATPPetrobactin biosynthesis protein AsbB/0.450
3u5ySCGRaucaffricine-O-beta-D-glucosidase3.2.1.1250.450
3wagTYDGlycosyltransferase/0.450
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.450
4bis8HQLysine-specific demethylase 4A1.14.110.450
4yfy0FXVioF/0.450
1b8oIMHPurine nucleoside phosphorylase2.4.2.10.449
1piwNAPNADP-dependent alcohol dehydrogenase 61.1.1.20.449
1t3zCAOFormyl-CoA:oxalate CoA-transferase/0.449
2pbwDOQGlutamate receptor ionotropic, kainate 1/0.449
3exhTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.449
3exhTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.449
3h2sNDPPutative NADH-flavin reductase/0.449
3ntrNADInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase1.1.1.180.449
3nx2FERFerulic acid decarboxylase/0.449
3rvhHQ2Lysine-specific demethylase 4A1.14.110.449
3wquATPCell division protein FtsA/0.449
4gv4MEJPoly [ADP-ribose] polymerase 32.4.2.300.449
4qaiFMNNADPH dehydrogenase/0.449
4uugPXGBranched-chain amino acid aminotransferase, putative/0.449
5fe112QHistone acetyltransferase KAT2B2.3.1.480.449
1a26CNAPoly [ADP-ribose] polymerase 12.4.2.300.448
1amoFADNADPH--cytochrome P450 reductase/0.448
1ni4TPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.448
1ni4TPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.448
1r5hAO2Methionine aminopeptidase 2/0.448
1sd1FMCS-methyl-5'-thioadenosine phosphorylase/0.448
1yplRA8Prothrombin3.4.21.50.448
2daaDCSD-alanine aminotransferase2.6.1.210.448
2xi4AFTAcetylcholinesterase3.1.1.70.448
2xlpFADPutative flavin-containing monooxygenase/0.448
2zrxFMNIsopentenyl-diphosphate delta-isomerase/0.448
3oetNADErythronate-4-phosphate dehydrogenase/0.448
3qftFADNADPH--cytochrome P450 reductase/0.448
3qgi33FGenome polyprotein2.7.7.480.448
3uelA1RPoly(ADP-ribose) glycohydrolase3.2.1.1430.448
3vilSA0Beta-glucosidase/0.448
3wqmB29Diterpene synthase3.1.7.80.448
4b1e6T6Beta-secretase 13.4.23.460.448
4bjcRPBTankyrase-22.4.2.300.448
4eu4COASuccinyl-CoA:acetate CoA-transferase/0.448
4m0f1YKAcetylcholinesterase3.1.1.70.448
4na4A1RPoly(ADP-ribose) glycohydrolase3.2.1.1430.448
7stdCRPScytalone dehydratase4.2.1.940.448
1ejiTHFSerine hydroxymethyltransferase, cytosolic/0.447
1ja1FMNNADPH--cytochrome P450 reductase/0.447
1nj6A5AProline--tRNA ligase/0.447
1obnASVIsopenicillin N synthase1.21.3.10.447
1q0zAKAAclacinomycin methylesterase RdmC3.1.1.950.447
1w4lGL8Acetylcholinesterase3.1.1.70.447
1ygkRRCPyridoxal kinase2.7.1.350.447
1zxmANPDNA topoisomerase 2-alpha5.99.1.30.447
2e8uIPEGeranylgeranyl pyrophosphate synthase/0.447
2jgsBTNAvidin/0.447
2uuk897Prothrombin3.4.21.50.447
2xdaJPS3-dehydroquinate dehydratase4.2.1.100.447
2zs8ADPPantothenate kinase2.7.1.330.447
3q9bB3NAcetylpolyamine amidohydrolase/0.447
4bfwZVWPantothenate kinase2.7.1.330.447
4kp71UQ1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic1.1.1.2670.447
4l1fCOSAcyl-CoA dehydrogenase domain protein/0.447
4odoFK5Peptidyl-prolyl cis-trans isomerase/0.447
1rxjBNIStreptavidin/0.446
1x2eATXProline iminopeptidase3.4.11.50.446
2b3dFADModulator of drug activity B/0.446
2gmuPDGPutative pyridoxamine 5-phosphate-dependent dehydrase/0.446
3arvSAUChitinase A/0.446
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
3g0bT22Dipeptidyl peptidase 4/0.446
3koyZ97D-ornithine 4,5-aminomutase subunit beta/0.446
4ge90L0Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.446
4lzwTHMUridine phosphorylase/0.446
5dw50T1Succinyl-CoA:acetate CoA-transferase/0.446
1a59COA2-methylcitrate synthase/0.445
1b8nIMGPurine nucleoside phosphorylase2.4.2.10.445
1cnfFADNitrate reductase [NADH]1.7.1.10.445
1j0xNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.445
1m4iCOAAminoglycoside 2'-N-acetyltransferase2.3.10.445
1nzq162Prothrombin3.4.21.50.445
1rr6IMHPurine nucleoside phosphorylase2.4.2.10.445
1tkaN3TTransketolase 12.2.1.10.445
1xp8AGSProtein RecA/0.445
2hk9NAPShikimate dehydrogenase (NADP(+))/0.445
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.445
3gr8FMNNADPH dehydrogenase/0.445
3i0aDBHNeutrophil gelatinase-associated lipocalin/0.445
3r43ID8Aldo-keto reductase family 1 member C3/0.445
3v0p4GWHisto-blood group ABO system transferase/0.445
4c73TLH3-oxoacyl-ACP synthase/0.445
4fpy0V8Sialidase B3.2.1.180.445
4hrqAZGCytidine and deoxycytidylate deaminase zinc-binding region/0.445
4jt81NRNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.445
4qtnNNRNicotinamide riboside transporter PnuC/0.445
4rphGDUUDP-galactopyranose mutase5.4.99.90.445
1v453DGPurine nucleoside phosphorylase2.4.2.10.444
1w35FADFerredoxin--NADP reductase1.18.1.20.444
1x1bSAHC-20 methyltransferase/0.444
2aj4ANPGalactokinase2.7.1.60.444
2c1zKMPAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.444
2fm0M98cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.444
2jb4A14Isopenicillin N synthase1.21.3.10.444
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.444
2qbuSAHPrecorrin-2 methyltransferase/0.444
2vf3GVS4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.444
2wzySQXSoluble acetylcholine receptor/0.444
2xviFADPutative flavin-containing monooxygenase/0.444
2z4y252Geranylgeranyl pyrophosphate synthase/0.444
3cotSTR3-oxo-5-beta-steroid 4-dehydrogenase/0.444
3go4SAHUncharacterized protein/0.444
3nu03TUDihydrofolate reductase1.5.1.30.444
3otbDGTProbable tRNA(His) guanylyltransferase2.7.7.790.444
3rpeFADPutative modulator of drug activity/0.444
3uzxAOM3-oxo-5-beta-steroid 4-dehydrogenase/0.444
3ziuLSSLeucyl-tRNA synthetase/0.444
4adcPLPSuccinylornithine transaminase2.6.1.810.444
4h0vNADIota toxin component Ia/0.444
4js1CTNBeta-galactoside alpha-2,6-sialyltransferase 12.4.99.10.444
4oew5IOcGMP-specific 3',5'-cyclic phosphodiesterase/0.444
4p9dTMPDeoxycytidylate deaminase/0.444
5fd8A5APutative carboxypeptidase yocD/0.444
5fm7ADPRuvB-like helicase/0.444
1ex75GPGuanylate kinase2.7.4.80.443
1h6cNDPGlucose--fructose oxidoreductase1.1.99.280.443
1mrkFMCRibosome-inactivating protein alpha-trichosanthin3.2.2.220.443
1pr1FMBPurine nucleoside phosphorylase DeoD-type/0.443
1yw8A75Methionine aminopeptidase 2/0.443
1z71L17Prothrombin3.4.21.50.443
1zgv501Prothrombin3.4.21.50.443
2gmsP0PPutative pyridoxamine 5-phosphate-dependent dehydrase/0.443
2msdGNPMHC class I alpha chain/0.443
2x1eX1EAcyl-coenzyme A:6-aminopenicillanic-acid-acyltransferase 40 kDa form2.3.1.1640.443
2xb9XNW3-dehydroquinate dehydratase4.2.1.100.443
2xujTZ5Acetylcholinesterase3.1.1.70.443
3b4yF42F420-dependent glucose-6-phosphate dehydrogenase/0.443
3ce0P34Poly [ADP-ribose] polymerase 32.4.2.300.443
3uptTPPTransketolase/0.443
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.443
4b1jA1RPoly(ADP-ribose) glycohydrolase3.2.1.1430.443
4c2z646Glycylpeptide N-tetradecanoyltransferase 1/0.443
4eb5PLPCysteine desulfurase IscS 2/0.443
4ffw715Dipeptidyl peptidase 4/0.443
1a9p9DIPurine nucleoside phosphorylase2.4.2.10.442
1bk0ACVIsopenicillin N synthase1.21.3.10.442
1blzACVIsopenicillin N synthase1.21.3.10.442
1cdoNADAlcohol dehydrogenase 11.1.1.10.442
1h60STRPentaerythritol tetranitrate reductase/0.442
1n4pCYS_VAL_ILE_LEU_GERGeranylgeranyl transferase type-1 subunit beta2.5.1.590.442
1pqc444Oxysterols receptor LXR-beta/0.442
1yhjR6CPyridoxal kinase2.7.1.350.442
2a1hGBNBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.442
2ea2F77Methionine aminopeptidase 2/0.442
2fb35ADGTP 3',8-cyclase4.1.99.180.442
2fhnBNIAvidin-related protein 4/5/0.442
2qtaTDPPyruvate dehydrogenase E1 component1.2.4.10.442
2w6pOA4Biotin carboxylase6.3.4.140.442
2wjoQUDBeta-secretase 13.4.23.460.442
3dr4G4MGDP-perosamine synthase/0.442
3gb4D3MDdmC/0.442
3iktNADRedox-sensing transcriptional repressor Rex/0.442
3lzwNAPFerredoxin--NADP reductase 21.18.1.20.442
3ndjJHZMethyltransferase/0.442
3s8xE59Carbonic anhydrase 24.2.1.10.442
4e2yJHZMethyltransferase/0.442
4ey6GNTAcetylcholinesterase3.1.1.70.442
4gts7TPGeranylgeranyl transferase type-2 subunit beta2.5.1.600.442
4gv08MEPoly [ADP-ribose] polymerase 32.4.2.300.442
4lxlPD2Lysine-specific demethylase 4B1.14.110.442
3uonQNBMuscarinic acetylcholine receptor M2/0.442
1bn3AL6Carbonic anhydrase 24.2.1.10.441
1fmjRTLRetinol dehydratase/0.441
1so2666cGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.441
2fj1CTCTetracycline repressor protein class D/0.441
2futH1SHeparin and heparin-sulfate lyase/0.441
2g1n1IGRenin3.4.23.150.441
2ieaTDPPyruvate dehydrogenase E1 component1.2.4.10.441
2re8GSUGlutamine--tRNA ligase6.1.1.180.441
2x93X93Angiotensin-converting enzyme3.4.15.10.441
2y6fM9FIsopenicillin N synthase1.21.3.10.441
3fazNOSPurine nucleoside phosphorylase/0.441
3geyP34Poly [ADP-ribose] polymerase 152.4.2.300.441
3hl0NADMaleylacetate reductase/0.441
3i8p8403-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.441
3jq6DX1Pteridine reductase, putative/0.441
3lq2TDPPyruvate dehydrogenase E1 component1.2.4.10.441
4a5lNDPThioredoxin reductase/0.441
4d2dALA_ALA_ALADi-or tripeptide:H+ symporter/0.441
4gsuDWZL,D-transpeptidase 22.3.20.441
4ikzAFSDi-tripeptide ABC transporter (Permease)/0.441
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.441
4mrm2BYGamma-aminobutyric acid type B receptor subunit 1/0.441
4stdBFSScytalone dehydratase4.2.1.940.441
1a4wQWEProthrombin3.4.21.50.440
1aiqCB3Thymidylate synthase/0.440
1cjvFOKAdenylate cyclase type 2/0.440
1cjvFOKAdenylate cyclase type 5/0.440
1d6w00RProthrombin3.4.21.50.440
1h66RH1NAD(P)H dehydrogenase [quinone] 11.6.5.20.440
1kt7RTLRetinol-binding protein 4/0.440
1lkeDOGBilin-binding protein/0.440
1szgFNSCytochrome b2, mitochondrial1.1.2.30.440
1t7o152Carnitine O-acetyltransferase2.3.1.70.440
1tilATPAnti-sigma F factor/0.440
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.440
1ycfFMNNitric oxide reductase10.440
2a59LMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.440
2ckmAA7Acetylcholinesterase3.1.1.70.440
2cndFADNitrate reductase [NADH]1.7.1.10.440
2gfxPMN3-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.440
2gyuHI6Acetylcholinesterase3.1.1.70.440
2iu8UD1UDP-3-O-acylglucosamine N-acyltransferase2.3.10.440
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.440
2p8uCOAHydroxymethylglutaryl-CoA synthase, cytoplasmic2.3.3.100.440
2vcmM11Isopenicillin N synthase1.21.3.10.440
2vqbFADPutative flavin-containing monooxygenase/0.440
2w6zL21Biotin carboxylase6.3.4.140.440
2xupTZ5Acetylcholinesterase3.1.1.70.440
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
3h7rNAPAldo-keto reductase family 4 member C8/0.440
3i6iNDPPutative leucoanthocyanidin reductase 1/0.440
4an4DUDPutative glycosyl transferase/0.440
4awsFMNNADH:flavin oxidoreductase Sye1/0.440
4bjbP34Tankyrase-22.4.2.300.440
4dk70KSOxysterols receptor LXR-beta/0.440
4eph0RKCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.440
4eqrCOACoenzyme A disulfide reductase/0.440
4u3jGTPTubulin beta chain/0.440
4u9zCOAAlpha-tubulin N-acetyltransferase 1/0.440
4zirANPEnergy-coupling factor transporter ATP-binding protein EcfA23.6.30.440
4zirANPEnergy-coupling factor transporter ATP-binding protein EcfA1/0.440