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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1dmyAZMCarbonic anhydrase 5A, mitochondrial4.2.1.1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
1dmyAZMCarbonic anhydrase 5A, mitochondrial4.2.1.11.000
1h50FMNPentaerythritol tetranitrate reductase/0.521
3mdzEZLCarbonic anhydrase 74.2.1.10.516
2g1n1IGRenin3.4.23.150.504
3in6FMNUncharacterized protein/0.501
3ziuLSSLeucyl-tRNA synthetase/0.498
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.495
4itoMPXCarbonic anhydrase 24.2.1.10.495
7stdCRPScytalone dehydratase4.2.1.940.495
3s1dZIRCytokinin dehydrogenase 11.5.99.120.494
3qykIE2Carbonic anhydrase 24.2.1.10.492
1icqFMN12-oxophytodienoate reductase 11.3.1.420.490
1n4pCYS_VAL_ILE_LEU_GERGeranylgeranyl transferase type-1 subunit beta2.5.1.590.490
1zsbAZMCarbonic anhydrase 24.2.1.10.488
3gkaFMNN-ethylmaleimide reductase/0.486
3oysOYSCarbonic anhydrase 24.2.1.10.486
4k13ETSCarbonic anhydrase 24.2.1.10.486
5dw60T1Succinyl-CoA:acetate CoA-transferase/0.484
4k0tD9ZCarbonic anhydrase 24.2.1.10.483
3kigDA4Carbonic anhydrase 24.2.1.10.482
3p67FMNPentaerythritol tetranitrate reductase/0.482
1x1bSAHC-20 methyltransferase/0.481
3k8q22APurine nucleoside phosphorylase2.4.2.10.481
3mnaDWHCarbonic anhydrase 24.2.1.10.481
4f1l0RYPoly [ADP-ribose] polymerase 142.4.2.300.481
4itp1GDCarbonic anhydrase 24.2.1.10.481
1if4FBSCarbonic anhydrase 24.2.1.10.479
3rz8RZ8Carbonic anhydrase 24.2.1.10.479
5fltVJJCarbonic anhydrase 24.2.1.10.479
1bn1AL5Carbonic anhydrase 24.2.1.10.478
3n0nP9BCarbonic anhydrase 24.2.1.10.478
4jicFMNGTN Reductase/0.478
2abbFMNPentaerythritol tetranitrate reductase/0.477
2c20NADUDP-glucose 4-epimerase/0.477
4bf19FKCarbonic anhydrase 24.2.1.10.477
1h51FMNPentaerythritol tetranitrate reductase/0.476
1jd0AZMCarbonic anhydrase 124.2.1.10.476
1rzuADPGlycogen synthase 12.4.1.210.476
4iwz1GOCarbonic anhydrase 24.2.1.10.476
4kap1QVCarbonic anhydrase 24.2.1.10.476
1kbo340NAD(P)H dehydrogenase [quinone] 11.6.5.20.475
1xe65FPPlasmepsin-23.4.23.390.475
3mzcS6ICarbonic anhydrase 24.2.1.10.475
4kxjP34Nucleoprotein/0.475
1kkq471Peroxisome proliferator-activated receptor alpha/0.474
2wejFB2Carbonic anhydrase 24.2.1.10.474
3atzFMNProstaglandin F2a synthase/0.474
3fhxPLPPyridoxal kinase2.7.1.350.474
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.474
3oimVZ5Carbonic anhydrase 24.2.1.10.474
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.473
1g54FFBCarbonic anhydrase 24.2.1.10.472
1oknSTBCarbonic anhydrase 24.2.1.10.472
3r96ACOMccE protein/0.472
3s3vTOPDihydrofolate reductase1.5.1.30.472
1o9bNAIQuinate/shikimate dehydrogenase/0.471
1udaUFGUDP-glucose 4-epimerase5.1.3.20.471
2g8yNADHydroxycarboxylate dehydrogenase B/0.471
3m2nJ74Carbonic anhydrase 24.2.1.10.471
3m5eJDRCarbonic anhydrase 24.2.1.10.471
3mhiJ90Carbonic anhydrase 24.2.1.10.471
3mmfD9HCarbonic anhydrase 24.2.1.10.471
3rpeFADPutative modulator of drug activity/0.471
3w5hFADNADH-cytochrome b5 reductase 31.6.2.20.471
4ilx1EZCarbonic anhydrase 24.2.1.10.471
1gj5130Prothrombin3.4.21.50.470
1kwqSG1Carbonic anhydrase 24.2.1.10.470
1w6hTITPlasmepsin-23.4.23.390.470
2gv8NDPThiol-specific monooxygenase1.14.130.470
2i65NADADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.470
2zvcSAHPrecorrin-3 C17-methyltransferase/0.470
3dzkNMNADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.470
3h3qH13Collagen type IV alpha-3-binding protein/0.470
3ixp834Ecdysone receptor/0.470
3lqfNADGalactitol dehydrogenase/0.470
3t82SG4Carbonic anhydrase 24.2.1.10.470
4a99FADTetX family tetracycline inactivation enzyme/0.470
4zj8SUVOrexin receptor type 1/0.470
1j49NADD-lactate dehydrogenase1.1.1.280.469
1qyw5SDEstradiol 17-beta-dehydrogenase 11.1.1.620.469
1vi2NADQuinate/shikimate dehydrogenase/0.469
2a94AP0L-lactate dehydrogenase1.1.1.270.469
2iyfERYOleandomycin glycosyltransferase2.4.10.469
2qimZEAClass 10 plant pathogenesis-related protein/0.469
3f03FMNPentaerythritol tetranitrate reductase/0.469
4ke11R6Beta-secretase 13.4.23.460.469
4mr92BXGamma-aminobutyric acid type B receptor subunit 1/0.469
2g1s4IGRenin3.4.23.150.468
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.468
3p62FMNPentaerythritol tetranitrate reductase/0.468
4dz7D02Carbonic anhydrase 24.2.1.10.468
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.468
4knjE1FCarbonic anhydrase 24.2.1.10.468
3dcwEZLCarbonic anhydrase 24.2.1.10.467
3g70A5TRenin3.4.23.150.467
3hgoFMN12-oxophytodienoate reductase 31.3.1.420.467
3mhoJ43Carbonic anhydrase 24.2.1.10.467
1beuIPLTryptophan synthase alpha chain/0.466
1bntAL2Carbonic anhydrase 24.2.1.10.466
1bwsNDPGDP-L-fucose synthase/0.466
1p0pBCHCholinesterase3.1.1.80.466
1x1aSAMC-20 methyltransferase/0.466
2g1o2IGRenin3.4.23.150.466
3jyoNADQuinate/shikimate dehydrogenase (NAD(+))/0.466
3m98E02Carbonic anhydrase 24.2.1.10.466
3tjzGNPADP-ribosylation factor 1/0.466
4m2vBZ1Carbonic anhydrase 24.2.1.10.466
1a9yUPGUDP-glucose 4-epimerase5.1.3.20.465
1h36R88Squalene--hopene cyclase4.2.1.1290.465
1h62ANBPentaerythritol tetranitrate reductase/0.465
1jdtMTAPurine nucleoside phosphorylase/0.465
3dc3AZMCarbonic anhydrase 24.2.1.10.465
3i8p8403-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.465
3p74FMNPentaerythritol tetranitrate reductase/0.465
3sbhE65Carbonic anhydrase 24.2.1.10.465
4tmcFMNOld yellow enzyme/0.465
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.464
3otwCOAPhosphopantetheine adenylyltransferase/0.464
3qt62P0Mevalonate diphosphate decarboxylase/0.464
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.464
1bn3AL6Carbonic anhydrase 24.2.1.10.463
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.463
1cnfFADNitrate reductase [NADH]1.7.1.10.463
1o2g696Prothrombin3.4.21.50.463
2dftADPShikimate kinase2.7.1.710.463
2q3rFMN12-oxophytodienoate reductase 11.3.1.420.463
2rlcCHDCholoylglycine hydrolase3.5.1.240.463
2z3lPHE_ARG_TYR_LEU_GLYLeucyl/phenylalanyl-tRNA--protein transferase2.3.2.60.463
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.463
4eagATP5'-AMP-activated protein kinase subunit gamma-1/0.463
1t4u81AProthrombin3.4.21.50.462
1z2iNADPutative malate dehydrogenase/0.462
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.462
3d9zD9ZCarbonic anhydrase 24.2.1.10.462
4bfzZVZPantothenate kinase2.7.1.330.462
4ycpFMNtRNA-dihydrouridine(16) synthase/0.462
1oq5CELCarbonic anhydrase 24.2.1.10.461
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.461
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.461
3e6eDCSAlanine racemase/0.461
4ef9FMNDihydroorotate dehydrogenase (fumarate)/0.461
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.461
4mrm2BYGamma-aminobutyric acid type B receptor subunit 1/0.461
1umaIN2Prothrombin3.4.21.50.460
2wehFB1Carbonic anhydrase 24.2.1.10.460
2weoFBWCarbonic anhydrase 24.2.1.10.460
3c1kT15Prothrombin3.4.21.50.460
3eu5GBOProtein farnesyltransferase subunit beta2.5.1.580.460
4e2dFMNDehydrogenase/0.460
1bil0IURenin3.4.23.150.459
1bnnAL1Carbonic anhydrase 24.2.1.10.459
1g52F2BCarbonic anhydrase 24.2.1.10.459
1nm6L86Prothrombin3.4.21.50.459
2i4qUA4Renin3.4.23.150.459
2q1wNADPutative nucleotide sugar epimerase/ dehydratase/0.459
3n4bWWZCarbonic anhydrase 24.2.1.10.459
3nl6TPSUncharacterized protein/0.459
3vydVYDRenin3.4.23.150.459
4bb3KKAIsopenicillin N synthase1.21.3.10.459
4bf6X0QCarbonic anhydrase 24.2.1.10.459
4hmz18TdTDP-4-dehydro-6-deoxyglucose 3-epimerase5.1.3.270.459
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.458
1q5mNDPProstaglandin-E(2) 9-reductase1.1.1.1890.458
1rj6AZMCarbonic anhydrase 144.2.1.10.458
1rszDIHPurine nucleoside phosphorylase2.4.2.10.458
2g1r3IGRenin3.4.23.150.458
2hs8FMN12-oxophytodienoate reductase 31.3.1.420.458
2rqfJH3Hemolymph juvenile hormone binding protein/0.458
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.458
3iqhTYR_ASP_ILECysteine synthase2.5.1.470.458
4kbyC2EStimulator of interferon genes protein/0.458
1b8vNADMalate dehydrogenase/0.457
1icpFMN12-oxophytodienoate reductase 11.3.1.420.457
1rfuADPPyridoxal kinase2.7.1.350.457
1tcoFK5Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.457
1tcoFK5Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform3.1.3.160.457
2d8aNADL-threonine 3-dehydrogenase/0.457
2g247IGRenin3.4.23.150.457
2h15B19Carbonic anhydrase 24.2.1.10.457
2he5NDPAldo-keto reductase family 1 member C211.1.10.457
2ikuLIYRenin3.4.23.150.457
2wegFBVCarbonic anhydrase 24.2.1.10.457
3dbuD8WCarbonic anhydrase 24.2.1.10.457
3eft3BSCarbonic anhydrase 24.2.1.10.457
3own3OWRenin3.4.23.150.457
4ddhMS0Pantothenate synthetase6.3.2.10.457
4gdcNDPUDP-galactopyranose mutase/0.457
4gv4MEJPoly [ADP-ribose] polymerase 32.4.2.300.457
4hfr14MCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.457
4q71FADBifunctional protein PutA/0.457
4rvdSAMD-mycarose 3-C-methyltransferase/0.457
6stdMS2Scytalone dehydratase4.2.1.940.457
2zvbSAHPrecorrin-3 C17-methyltransferase/0.456
3a0tADPSensor histidine kinase/0.456
3b6zCO7Enoyl reductase LovC10.456
3mhlJ71Carbonic anhydrase 24.2.1.10.456
3po6DT9Carbonic anhydrase 24.2.1.10.456
3t85SG7Carbonic anhydrase 24.2.1.10.456
3uzzASD3-oxo-5-beta-steroid 4-dehydrogenase/0.456
4i13FOLDihydrofolate reductase1.5.1.30.456
4kp5E1FCarbonic anhydrase 124.2.1.10.456
1fmlRTLRetinol dehydratase/0.455
1i7pFADNADH-cytochrome b5 reductase 31.6.2.20.455
1if5FBTCarbonic anhydrase 24.2.1.10.455
1rkwPNTHTH-type transcriptional regulator QacR/0.455
2a0xDIHPurine nucleoside phosphorylase2.4.2.10.455
2g1y5IGRenin3.4.23.150.455
2stdCRPScytalone dehydratase4.2.1.940.455
3dazMZMCarbonic anhydrase 24.2.1.10.455
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.455
3ffpLC1Carbonic anhydrase 24.2.1.10.455
3ld6BCDLanosterol 14-alpha demethylase1.14.13.700.455
3nmpPYVAbscisic acid receptor PYL2/0.455
4g2rH1LProbable propionyl-CoA carboxylase beta chain 66.4.1.30.455
4gv08MEPoly [ADP-ribose] polymerase 32.4.2.300.455
4k28NADShikimate dehydrogenase family protein/0.455
1d0lBLGMembrane-bound lytic murein transglycosylase B4.2.2.n10.454
1h6cNDPGlucose--fructose oxidoreductase1.1.99.280.454
1if6FBUCarbonic anhydrase 24.2.1.10.454
1pd9CO4Dihydrofolate reductase1.5.1.30.454
1sq5ADPPantothenate kinase2.7.1.330.454
2ggsNDPdTDP-4-dehydrorhamnose reductase/0.454
2xviFADPutative flavin-containing monooxygenase/0.454
3fr5I4AFatty acid-binding protein, adipocyte/0.454
3isjA8DPantothenate synthetase6.3.2.10.454
3jypNADQuinate/shikimate dehydrogenase (NAD(+))/0.454
3m96E38Carbonic anhydrase 24.2.1.10.454
3t84SG6Carbonic anhydrase 24.2.1.10.454
3zbsOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.454
4rnuFMNNADPH dehydrogenase 11.6.99.10.454
4x5sAZMCarbonic anhydrase (Carbonate dehydratase)/0.454
1gw2FERPeroxidase C1A1.11.1.70.453
1h74AGSHomoserine kinase2.7.1.390.453
1j9zFADNADPH--cytochrome P450 reductase/0.453
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.453
1xe55FEPlasmepsin-23.4.23.390.453
2g226IGRenin3.4.23.150.453
2pobGW4Peroxisome proliferator-activated receptor gamma/0.453
3gfbNADL-threonine 3-dehydrogenase/0.453
3h3r14HCollagen type IV alpha-3-binding protein/0.453
3hatGLY_VAL_ARG_RNGProthrombin3.4.21.50.453
3lqsPSZD-alanine aminotransferase2.6.1.210.453
3mpjFADGlutaryl-CoA dehydrogenase1.3.99.320.453
3ni5C1HCarbonic anhydrase 24.2.1.10.453
3vyfVYFRenin3.4.23.150.453
3wqmB29Diterpene synthase3.1.7.80.453
4a862ANMajor pollen allergen Bet v 1-A/0.453
4b68NAPL-ornithine N(5)-monooxygenase/0.453
4eu4COASuccinyl-CoA:acetate CoA-transferase/0.453
4jnkZHKL-lactate dehydrogenase A chain1.1.1.270.453
4m2rBZ1Carbonic anhydrase 24.2.1.10.453
1cnyEG3Carbonic anhydrase 24.2.1.10.452
1qx4FADNADH-cytochrome b5 reductase 31.6.2.20.452
1u1gBBBUridine phosphorylase2.4.2.30.452
1zji2PG2-dehydro-3-deoxyphosphooctonate aldolase2.5.1.550.452
2q1uNADPutative nucleotide sugar epimerase/ dehydratase/0.452
2r5nTPPTransketolase 1/0.452
3e8xNAPBH1520 protein/0.452
3m40J45Carbonic anhydrase 24.2.1.10.452
4cr8NADN-acylmannosamine 1-dehydrogenase1.1.1.2330.452
4ge90L0Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.452
1d3pBT3Prothrombin3.4.21.50.451
1h63FMNPentaerythritol tetranitrate reductase/0.451
1k4mNADNicotinate-nucleotide adenylyltransferase2.7.7.180.451
1pq944BOxysterols receptor LXR-beta/0.451
1qpl587Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.451
1t4cCOAFormyl-CoA:oxalate CoA-transferase/0.451
1tllFMNNitric oxide synthase, brain1.14.13.390.451
1udbUFGUDP-glucose 4-epimerase5.1.3.20.451
1vyrFMNPentaerythritol tetranitrate reductase/0.451
1w34FADFerredoxin--NADP reductase1.18.1.20.451
1wngSAHDiphthine synthase/0.451
2a58RBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.451
3ekuCY9Actin-5C/0.451
3elbC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.451
3f4xKLTCarbonic anhydrase 24.2.1.10.451
3i0aDBHNeutrophil gelatinase-associated lipocalin/0.451
3m2yBE0Carbonic anhydrase 24.2.1.10.451
3s8xE59Carbonic anhydrase 24.2.1.10.451
4m83ERYOleandomycin glycosyltransferase2.4.10.451
4rlh0WEEnoyl-[acyl-carrier-protein] reductase [NADH]/0.451
4xrbNDPPossible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc/0.451
5einNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.451
1cnwEG1Carbonic anhydrase 24.2.1.10.450
1d2hSAHGlycine N-methyltransferase2.1.1.200.450
1ta6177Prothrombin3.4.21.50.450
1towCRZFatty acid-binding protein, adipocyte/0.450
1x1cSAHC-20 methyltransferase/0.450
1xq04TRCarbonic anhydrase 24.2.1.10.450
2cv2GSUGlutamate--tRNA ligase6.1.1.170.450
2f3rG5PGuanylate kinase2.7.4.80.450
2gd6ACOProbable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase )/0.450
2hs6FMN12-oxophytodienoate reductase 31.3.1.420.450
2x7uWZACarbonic anhydrase 24.2.1.10.450
2ylrNAPPhenylacetone monooxygenase1.14.13.920.450
3eksCY9Actin-5C/0.450
3h2sNDPPutative NADH-flavin reductase/0.450
3i0pNADMalate dehydrogenase, putative/0.450
3otbDGTProbable tRNA(His) guanylyltransferase2.7.7.790.450
3zncBZ1Carbonic anhydrase 44.2.1.10.450
4cjx9L9C-1-tetrahydrofolate synthase, cytoplasmic, putative/0.450
4gddNAIUDP-galactopyranose mutase/0.450
1g1dFSBCarbonic anhydrase 24.2.1.10.449
1hkuNADC-terminal-binding protein 11.1.10.449
1i59ANPChemotaxis protein CheA2.7.13.30.449
1kh3ANPArgininosuccinate synthase/0.449
1kt8ILPBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.449
1t2cNAIL-lactate dehydrogenase1.1.1.270.449
1tkaN3TTransketolase 12.2.1.10.449
1toiHCIAspartate aminotransferase2.6.1.10.449
1x2hLPALipoate-protein ligase A6.3.1.200.449
2cy0NAPShikimate dehydrogenase (NADP(+))/0.449
2eu3FF3Carbonic anhydrase 24.2.1.10.449
2q28ADPOxalyl-CoA decarboxylase4.1.1.80.449
2q7oIMHPurine nucleoside phosphorylase2.4.2.10.449
2y3sTIRTamL/0.449
2zc922UProthrombin3.4.21.50.449
3d91REMRenin3.4.23.150.449
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.449
3m2vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.449
3nb5R21Carbonic anhydrase 24.2.1.10.449
3t4hMD5Alpha-ketoglutarate-dependent dioxygenase AlkB1.14.11.330.449
3uoxFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.449
4a83DXCMajor pollen allergen Bet v 1-A/0.449
4dan2FAPurine nucleoside phosphorylase DeoD-type2.4.2.10.449
4eb5PLPCysteine desulfurase IscS 2/0.449
4k0zMZMCarbonic anhydrase 24.2.1.10.449
4rrrA3TThreonine--tRNA ligase6.1.1.30.449
4yaiNAIC alpha-dehydrogenase/0.449
5hi6MTXDihydrofolate reductase/0.449
1bn4AL9Carbonic anhydrase 24.2.1.10.448
1lf3EH5Plasmepsin-23.4.23.390.448
1u1f183Uridine phosphorylase2.4.2.30.448
1ypeUIPProthrombin3.4.21.50.448
2dc1NADProbable L-aspartate dehydrogenase/0.448
2dhfDZFDihydrofolate reductase1.5.1.30.448
2ejkSAHDiphthine synthase/0.448
2fxv5GPXanthine phosphoribosyltransferase2.4.2.220.448
2g5w8PG12-oxophytodienoate reductase 31.3.1.420.448
2rcyNAPPyrroline-5-carboxylate reductase/0.448
3b1dPLSBetaC-S lyase/0.448
3myqE27Carbonic anhydrase 24.2.1.10.448
3zeiAWHO-acetylserine sulfhydrylase/0.448
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.448
4g95OAGDihydrofolate reductase1.5.1.30.448
1c3x8IGPurine nucleoside phosphorylase2.4.2.10.447
1jdvADNPurine nucleoside phosphorylase/0.447
1kwrSG2Carbonic anhydrase 24.2.1.10.447
1t4v14AProthrombin3.4.21.50.447
1zxnADPDNA topoisomerase 2-alpha5.99.1.30.447
2lfoGCHFatty acid-binding protein, liver/0.447
2ohvNHLGlutamate racemase/0.447
2vbdV10Isopenicillin N synthase1.21.3.10.447
2y4gTIRTamL/0.447
2zsaADPPantothenate kinase2.7.1.330.447
3btsNADGalactose/lactose metabolism regulatory protein GAL80/0.447
3dcsMZMCarbonic anhydrase 24.2.1.10.447
3e34ED1Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.447
3e34ED1Protein farnesyltransferase subunit beta2.5.1.580.447
3jusBCDLanosterol 14-alpha demethylase1.14.13.700.447
3rtnRTNBeta-secretase 13.4.23.460.447
3sbiE90Carbonic anhydrase 24.2.1.10.447
3t4eNADQuinate/shikimate dehydrogenase/0.447
3zoiM2WIsopenicillin N synthase1.21.3.10.447
4a8v2ANMajor pollen allergen Bet v 1-J/0.447
4bfwZVWPantothenate kinase2.7.1.330.447
4r81FMNPredicted NADH dehydrogenase/0.447
4x7zZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.447
4y3jHICEndothiapepsin3.4.23.220.447
1drhNAPDihydrofolate reductase1.5.1.30.446
1g4tFTPThiamine-phosphate synthase/0.446
1h74ADPHomoserine kinase2.7.1.390.446
1hb3SCVIsopenicillin N synthase1.21.3.10.446
1kp2ATPArgininosuccinate synthase6.3.4.50.446
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.446
1qiqACCIsopenicillin N synthase1.21.3.10.446
1qlhNADAlcohol dehydrogenase E chain1.1.1.10.446
1rfgGMPPurine nucleoside phosphorylase2.4.2.10.446
1xddAAYIntegrin alpha-L/0.446
2qw034Z4-chlorobenzoyl CoA ligase/0.446
2r2mI50Prothrombin3.4.21.50.446
2vyqFADFerredoxin--NADP reductase1.18.1.20.446
2xupTZ5Acetylcholinesterase3.1.1.70.446
3betCTFCarbonic anhydrase 24.2.1.10.446
3d8wD8WCarbonic anhydrase 24.2.1.10.446
3gqvNAPEnoyl reductase LovC10.446
3hgrFMN12-oxophytodienoate reductase 11.3.1.420.446
3iqgASN_TRP_ASN_ILECysteine synthase2.5.1.470.446
3kjm245Cytokinin dehydrogenase 11.5.99.120.446
3t4nADP5'-AMP-activated protein kinase subunit gamma/0.446
4cfaWOPIntegrase/0.446
4i6gFADCryptochrome-2/0.446
4kgkGTPUncharacterized protein/0.446
4na4A1RPoly(ADP-ribose) glycohydrolase3.2.1.1430.446
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.446
1d3dBZTProthrombin3.4.21.50.445
1i90INMCarbonic anhydrase 24.2.1.10.445
1i91INQCarbonic anhydrase 24.2.1.10.445
1kc1NDPdTDP-4-dehydrorhamnose reductase1.1.1.1330.445
1pqc444Oxysterols receptor LXR-beta/0.445
1rneC60Renin3.4.23.150.445
1rt9IMHPurine nucleoside phosphorylase2.4.2.10.445
1x8lOXRRetinol dehydratase/0.445
2briANPUridylate kinase2.7.4.220.445
2g20L1ARenin3.4.23.150.445
2ga2A19Methionine aminopeptidase 2/0.445
2wzwNDPNitroreductase NfnB/0.445
2z4sADPChromosomal replication initiator protein DnaA/0.445
3oyqOYQCarbonic anhydrase 24.2.1.10.445
3saxE50Carbonic anhydrase 24.2.1.10.445
3u9fCLMChloramphenicol acetyltransferase2.3.1.280.445
3up4FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.445
4ax9N5NProthrombin3.4.21.50.445
4bftZVTPantothenate kinase2.7.1.330.445
4c36ZO9cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
4g8jTHMUridine phosphorylase/0.445
4p9dTMPDeoxycytidylate deaminase/0.445
4x7wMVIMycinamicin III 3''-O-methyltransferase2.1.1.2370.445
4y1bNAPAntE/0.445
4ycoFMNtRNA-dihydrouridine(16) synthase/0.445
1a9zUPGUDP-glucose 4-epimerase5.1.3.20.444
1n95HFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.444
1n95HFPProtein farnesyltransferase subunit beta2.5.1.580.444
1sa5BMVProtein farnesyltransferase subunit beta2.5.1.580.444
1xvaSAMGlycine N-methyltransferase2.1.1.200.444
2a0wDIHPurine nucleoside phosphorylase2.4.2.10.444
2dfvNADL-threonine 3-dehydrogenase/0.444
2ewvADPTwitching motility protein PilT/0.444
2v16C47Renin3.4.23.150.444
2xlpFADPutative flavin-containing monooxygenase/0.444
2zbaZBATrichothecene 3-O-acetyltransferase/0.444
3dccD9ZCarbonic anhydrase 24.2.1.10.444
3dziRGTADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.444
3lzxFADFerredoxin--NADP reductase 21.18.1.20.444
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.444
3phiNDPShikimate dehydrogenase (NADP(+))/0.444
3s5wFADL-ornithine N(5)-monooxygenase/0.444
4an4DUDPutative glycosyl transferase/0.444
4b67FADL-ornithine N(5)-monooxygenase/0.444
4dbc3QPAspartate aminotransferase2.6.1.10.444
4mr72BVGamma-aminobutyric acid type B receptor subunit 1/0.444
4nd2A3DLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.444
4wuoNAD3-isopropylmalate dehydrogenase1.1.1.850.444
1me6IVSPlasmepsin-23.4.23.390.443
1oklMNSCarbonic anhydrase 24.2.1.10.443
1v5z2HCMajor NAD(P)H-flavin oxidoreductase1.6.990.443
2aa3AP0L-lactate dehydrogenase/0.443
2hfuMEVMevalonate kinase/0.443
2iviACWIsopenicillin N synthase1.21.3.10.443
2p8hMY9Beta-secretase 13.4.23.460.443
3dgqEAAGlutathione S-transferase P2.5.1.180.443
3mhcARZCarbonic anhydrase 24.2.1.10.443
3qizQI2Botulinum neurotoxin type A3.4.24.690.443
3tozNADShikimate dehydrogenase (NADP(+))/0.443
4br0AU1Ectonucleoside triphosphate diphosphohydrolase 2/0.443
4eph0RKCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.443
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.443
4ho6UTPGlucose-1-phosphate thymidylyltransferase/0.443
4i1nFOLDihydrofolate reductase1.5.1.30.443
4yqfGDPSeptin-9/0.443
1bxkNADdTDP-glucose 4,6-dehydratase 2/0.442
1ld8U49Protein farnesyltransferase subunit beta2.5.1.580.442
1npdNADQuinate/shikimate dehydrogenase/0.442
1qoqIGPTryptophan synthase alpha chain/0.442
1ra8FOLDihydrofolate reductase1.5.1.30.442
1tqf32PBeta-secretase 13.4.23.460.442
2cndFADNitrate reductase [NADH]1.7.1.10.442
2j2pSC2Ficolin-2/0.442
2ojtUBAGlutamate receptor ionotropic, kainate 1/0.442
2q85973UDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.442
2x06NADL-sulfolactate dehydrogenase/0.442
2x7tWZBCarbonic anhydrase 24.2.1.10.442
3cotSTR3-oxo-5-beta-steroid 4-dehydrogenase/0.442
3h06VBPGlutamate receptor 2/0.442
3hlwCE3Beta-lactamase/0.442
3kpbSAMUncharacterized protein MJ0100/0.442
3m2uCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.442
3own3OXRenin3.4.23.150.442
3p80P80Pentaerythritol tetranitrate reductase/0.442
3r7kFDAProbable acyl CoA dehydrogenase/0.442
3tqxPLP2-amino-3-ketobutyrate coenzyme A ligase/0.442
4fuj1U9Urokinase-type plasminogen activator3.4.21.730.442
4lxb7R9Prothrombin3.4.21.50.442
4ms1381Gamma-aminobutyric acid type B receptor subunit 1/0.442
4v2gITCTetracycline repressor protein class D/0.442
4yagNAIC alpha-dehydrogenase/0.442
1ezvUQ6Cytochrome b/0.441
1hb1OCVIsopenicillin N synthase1.21.3.10.441
1ia1NDPDihydrofolate reductase1.5.1.30.441
1ndhFADNADH-cytochrome b5 reductase 31.6.2.20.441
1zxmANPDNA topoisomerase 2-alpha5.99.1.30.441
2abaSTRPentaerythritol tetranitrate reductase/0.441
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.441
2el0SAHDiphthine synthase/0.441
2ewmNAD(S)-1-Phenylethanol dehydrogenase1.1.1.3110.441
2gz7D3FOrf1a polyprotein/0.441
2jgsBTNAvidin/0.441
3igpDT7Carbonic anhydrase 24.2.1.10.441
3jyqNADQuinate/shikimate dehydrogenase (NAD(+))/0.441
4c0bATPmRNA cleavage and polyadenylation factor CLP1/0.441
4df2FMNNADPH dehydrogenase/0.441
4e2bFMNDehydrogenase/0.441
4ejmNAPPutative zinc-binding dehydrogenase/0.441
4eywL0RCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.441
4req5ADMethylmalonyl-CoA mutase large subunit5.4.99.20.441
1dyiFOLDihydrofolate reductase1.5.1.30.440
1g6kNADGlucose 1-dehydrogenase1.1.1.470.440
1ib0NADNADH-cytochrome b5 reductase 31.6.2.20.440
1nvtNAPShikimate dehydrogenase (NADP(+))/0.440
1nzdUPGDNA beta-glucosyltransferase/0.440
1obnASVIsopenicillin N synthase1.21.3.10.440
1sa4JANProtein farnesyltransferase subunit beta2.5.1.580.440
1ttm667Carbonic anhydrase 24.2.1.10.440
2dvlFADAcyl-CoA dehydrogenase/0.440
2emrSAHDiphthine synthase/0.440
2il2LIXRenin3.4.23.150.440
2qtaTDPPyruvate dehydrogenase E1 component1.2.4.10.440
2xfyACXBeta-amylase3.2.1.20.440
2z3nPHE_ARG_TYR_LEU_GLYLeucyl/phenylalanyl-tRNA--protein transferase2.3.2.60.440
3a3gDLZLumazine protein/0.440
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
3e23SAMUncharacterized protein/0.440
3gwdNAPCyclohexanone monooxygenase/0.440
3hl0NADMaleylacetate reductase/0.440
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
4ccqFADThioredoxin reductase/0.440
4hyvPEPPyruvate kinase 12.7.1.400.440
4q0kGA3Phytohormone-binding protein/0.440
4xguADPPutative pachytene checkpoint protein 2/0.440
5choFADFlavin reductase/0.440